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https://www.readbyqxmd.com/read/28991332/visual-performance-with-bifocal-and-trifocal-diffractive-intraocular-lenses-a-prospective-three-armed-randomized-multicenter-clinical-trial
#1
Hakan Kaymak, Detlev Breyer, Jorge L Alió, Beatrice Cochener
PURPOSE: To evaluate and compare quality of vision and reading performance outcomes after implantation of bifocal refractive-diffractive, bifocal apodized diffractive, or trifocal diffractive-refractive intraocular lenses (IOLs). METHODS: This randomized, prospective, three-armed multicenter (Spain, Germany, and France) trial included 104 eyes of 52 patients (mean age: 63.2 ± 7.7 years). Patients underwent cataract surgery with bilateral implantation of either AT LISA 809M (Carl Zeiss Meditec, Jena, Germany: AT LISA group, 38 eyes), AT LISA tri 839MP (Carl Zeiss Meditec: AT LISA tri group, 32 eyes), or ReSTOR SN6AD1 (Alcon Laboratories, Inc...
October 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28981414/design-and-optimization-of-shf-composite-fbar-resonators
#2
Gayathri Pillai, Anurag A Zope, Julius Ming-Lin Tsai, Sheng-Shian Li
We propose an apodization technique based composite thin Film Bulk Acoustic wave Resonator (c-FBAR) design to enable the displacement and strain energy confinement at the central section of the resonator while in operation at the resonance mode. Sinc-shaped AlN on SOI apodized c-FBARs are designed to attain close to 90% energy localization. In this work, single crystal silicon as the mechanical layer and AlN piezoelectric material as the transducer layer of the resonator implemented by InvenSense Inc.'s AlN MEMS-CMOS platform renders an asymmetric feature to the traditional FBAR resonator...
October 5, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28967072/visual-outcomes-after-progressive-apodized-diffractive-intraocular-lens-implantation
#3
Javier García-Bella, Néstor Ventura-Abreu, Laura Morales-Fernández, Paula Talavero-González, Jesús Carballo-Álvarez, Juan Carlos Sanz-Fernández, José M Vázquez-Moliní, José M Martínez-de-la-Casa
PURPOSE: To assess photopic and mesopic vision in patients implanted with the Bi-Flex® M 677 MY bifocal intraocular lens (IOL). METHODS: In this prospective clinical study, 25 patients with cataract in both eyes were subjected to cataract surgery and bilateral implantation of the Bi-Flex® M 677MY (Medicontur, Hungary) IOL. Three months after surgery, high-contrast photopic uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA) were determined...
September 11, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28957310/single-focus-spiral-zone-plates
#4
Yonghao Liang, Enliang Wang, Yilei Hua, Changqing Xie, Tianchun Ye
We extend the concept of spiral zone plates along the optical axis and define a specific single optical element, termed as single-focus spiral zone plates (SFSZPs), for the generation of a single-focus vortex beam. The key idea is to make the transmittance of the spiral zone plates sinusoidal in the azimuthal direction. Furthermore, a two-parameter modified sinusoidal apodization window is introduced to modulate the transmittance function. Theoretical analysis reveals that the third-order diffraction light intensity of the SFSZPs could be reduced by more than three orders of magnitude compared to a conventional spiral zone plate...
July 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28957285/unidirectional-waveguide-grating-antennas-with-uniform-emission-for-optical-phased-arrays
#5
Manan Raval, Christopher V Poulton, Michael R Watts
We demonstrate millimeter-scale optical waveguide grating antennas with unidirectional emission for integrated optical phased arrays. Unidirectional emission eliminates the fundamental problem of blind spots in the element factor of a phased array caused by reflections of antenna radiation within the substrate. Over 90% directionality is demonstrated using a design consisting of two silicon nitride layers. Furthermore, the perturbation strength along the antenna is apodized to achieve uniform emission for the first time, to the best of our knowledge, on a millimeter scale...
July 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28914903/experimental-demonstration-of-an-apodized-imaging-chip-fiber-grating-coupler-for-si3n4-waveguides
#6
Yang Chen, Thalia Domínguez Bucio, Ali Z Khokhar, Mehdi Banakar, Katarzyna Grabska, Frederic Y Gardes, Robert Halir, Íñigo Molina-Fernández, Pavel Cheben, Jian-Jun He
A silicon nitride waveguide is a promising platform for integrated photonics, particularly due to its low propagation loss compared to other complementary metal-oxide-semiconductor compatible waveguides, including silicon-on-insulator. Input/output coupling in such thin optical waveguides is a key issue for practical implementations. Fiber-to-chip grating couplers in silicon nitride usually exhibit low coupling efficiency because the moderate index contrast leads to weak radiation strengths and poor directionality...
September 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28913938/application-of-craft-complete-reduction-to-amplitude-frequency-table-in-nonuniformly-sampled-nus-2d-nmr-data-processing
#7
Krish Krishnamurthy, Natarajan Hari
The recently published CRAFT (complete reduction to amplitude frequency table) technique converts the raw FID data (i.e., time domain data) into a table of frequencies, amplitudes, decay rate constants, and phases. It offers an alternate approach to decimate time-domain data, with minimal preprocessing step. It has been shown that application of CRAFT technique to process the t1 dimension of the 2D data significantly improved the detectable resolution by its ability to analyze without the use of ubiquitous apodization of extensively zero-filled data...
September 15, 2017: Magnetic Resonance in Chemistry: MRC
https://www.readbyqxmd.com/read/28842423/activation-of-liver-x-receptor-suppresses-angiogenesis-via-induction-of-apod
#8
Chih-Jen Lai, Hsu-Chen Cheng, Ching-Yu Lin, Shih-Han Huang, Ting-Huan Chen, Chi-Jung Chung, Chung-Ho Chang, Horng-Dar Wang, Chih-Pin Chuu
Liver X receptors (LXRs) are important sensors and regulators for cholesterol, fatty acid, and glucose. LXRs play essential roles in the development and progression of cardiovascular diseases. We examined the effects of T0901317, a potent LXR agonist, on angiogenesis of human umbilical vein endothelial cells (HUVECs). Treatment with T0901317 inhibited the tube formation and migration of HUVECs as well as reduced the in vivo angiogenesis determined by chorioallantoic membrane assay. T0901317 stimulated gene and protein expression of LXR target gene apolipoprotein D (ApoD)...
August 21, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28790805/bilateral-implantation-of-3-0-d-multifocal-toric-intraocular-lenses-results-of-a-us-food-and-drug-administration-clinical-trial
#9
Robert Lehmann, Satish Modi, Bret Fisher, Magda Michna, Michael Snyder
PURPOSE: The purpose of this study was to evaluate the clinical outcomes of apodized diffractive +3.0 D multifocal toric intraocular lens (IOL) implantations in subjects with preoperative corneal astigmatism. PATIENTS AND METHODS: This was a prospective cohort study conducted at 21 US sites. The study population consisted of 574 subjects, aged ≥21 years, with preoperative astigmatism 0.75-2.82 D, and potential postoperative visual acuity (VA) ≥0.2 logMAR, undergoing bilateral cataract removal by phacoemulsification...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28695482/role-of-apolipoproteins-and-%C3%AE-synuclein-in-parkinson-s-disease
#10
REVIEW
Fatemeh Nouri Emamzadeh
Parkinson's disease (PD) is a progressive brain disorder that interferes with activities of normal life. The main pathological feature of this disease is the loss of more than 80% of dopamine-producing neurons in the substantia nigra (SN). Dopaminergic neuronal cell death occurs when intraneuronal, insoluble, aggregated proteins start to form Lewy bodies (LBs), the most important component of which is a protein called α-synuclein (α-syn). α-Syn structurally contains hexameric repeats of 11 amino acids, which are characteristic of apolipoproteins and thus α-syn can also be considered an apolipoprotein...
August 2017: Journal of Molecular Neuroscience: MN
https://www.readbyqxmd.com/read/28636792/mtf-and-dqe-enhancement-using-an-apodized-aperture-x-ray-detector-design
#11
Tomi F Nano, Terenz Escartin, Elina Ismailova, Karim S Karim, Jan Lindström, Ho Kyung Kim, Ian A Cunningham
PURPOSE: Acquisition of high-quality x-ray images using low patient exposures requires detectors with high detective quantum efficiency (DQE). We describe a novel apodized-aperture pixel (AAP) design that increases high-frequency modulation transfer function (MTF) and DQE values. The AAP design makes a separation of physical sensor elements from image pixels by using very small sensor elements (e.g., 0.010-0.025 mm) to synthesize desired larger image pixels (e.g., 0.1-0.2 mm). METHODS: A cascaded systems model of signal and noise propagation is developed to describe the benefits of the AAP approach in terms of the MTF, Wiener noise power spectrum (NPS), and DQE...
June 21, 2017: Medical Physics
https://www.readbyqxmd.com/read/28626289/comparison-of-high-resolution-x-ray-detectors-with-conventional-fpds-using-experimental-mtfs-and-apodized-aperture-pixel-design-for-reduced-aliasing
#12
A Shankar, M Russ, S Vijayan, D R Bednarek, S Rudin
Apodized Aperture Pixel (AAP) design, proposed by Ismailova et. al, is an alternative to the conventional pixel design(1). The advantages of AAP processing with a sinc filter in comparison with using other filters include non-degradation of MTF values and elimination of signal and noise aliasing, resulting in an increased performance at higher frequencies, approaching the Nyquist frequency(3). If high resolution small field-of-view (FOV) detectors with small pixels used during critical stages of Endovascular Image Guided Interventions (EIGIs) could also be extended to cover a full field-of-view typical of flat panel detectors (FPDs) and made to have larger effective pixels, then methods must be used to preserve the MTF over the frequency range up to the Nyquist frequency of the FPD while minimizing aliasing...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28599255/research-on-two-port-network-of-wavelet-transform-processor-using-surface-acoustic-wavelet-devices-and-its-application
#13
Shoubing Liu, Wenke Lu, Changchun Zhu
The goal of this research is to study two-port network of wavelet transform processor (WTP) using surface acoustic wave (SAW) devices and its application. The motive was prompted by the inconvenience of the long research and design cycle and the huge research funding involved with traditional method in this field, which were caused by the lack of the simulation and emulation method of WTP using SAW devices. For this reason, we introduce the two-port network analysis tool, which has been widely used in the design and analysis of SAW devices with uniform interdigital transducers (IDTs)...
November 2017: Ultrasonics
https://www.readbyqxmd.com/read/28505094/antigiardial-activity-of-podophyllotoxin-type-lignans-from-bursera-fagaroides-var-fagaroides
#14
Filiberto Gutiérrez-Gutiérrez, Ana María Puebla-Pérez, Sirenia González-Pozos, José Manuel Hernández-Hernández, Armando Pérez-Rangel, Laura Patricia Alvarez, Gabriela Tapia-Pastrana, Araceli Castillo-Romero
Giardiasis, a diarrheal disease, is highly prevalent in developing countries. Several drugs are available for the treatment of this parasitosis; unfortunately, all of them have variable efficacies and adverse effects. Bursera fagaroides has been known for its anti-inflammatory and antidiarrheal properties in Mexican traditional medicine. We investigated the in vitro anti-giardial activities of four podophyllotoxin-type lignans from Bursera fagaroides var. fagaroides, namely, 5'-desmethoxy-β-peltatin-A-methylether (5-DES), acetylpodophyllotoxin (APOD), burseranin (BUR), and podophyllotoxin (POD)...
May 13, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28485374/serum-glycopattern-and-maackia-amurensis-lectin-ii-binding-glycoproteins-in-autism-spectrum-disorder
#15
Yannan Qin, Yanni Chen, Juan Yang, Fei Wu, Lingyu Zhao, Fuquan Yang, Peng Xue, Zhuoyue Shi, Tusheng Song, Chen Huang
The pathophysiology of autistic spectrum disorder (ASD) is not fully understood and there are no diagnostic or predictive biomarkers. Glycosylation modified as many as 70% of all human proteins can sensitively reflect various pathological changes. However, little is known about the alterations of glycosylation and glycoproteins in ASD. In this study, serum glycopattern and the maackia amurensis lectin-II binding glycoproteins (MBGs) in 65 children with ASD and 65 age-matched typically developing (TD) children were compared by using lectin microarrays and lectin-magnetic particle conjugate-assisted LC-MS/MS analyses...
May 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28463340/relating-wavefront-error-apodization-and-the-optical-transfer-function-general-case
#16
Jim Schwiegerling
In a previous paper, a technique was developed for decomposing the incoherent optical transfer function (OTF) into a linear combination of basis functions [J. Opt. Soc. Am. A31, 2476 (2014)JOAOD60740-323210.1364/JOSAA.31.002476]. The expansion coefficients for the OTF are directly related to wavefront error coefficients and apodization factors. This earlier work assumed rotational symmetry, so that only the on-axis wavefront error components, defocus and various orders of spherical aberration, and rotationally symmetric apodization were handled...
May 1, 2017: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/28452749/fresnel-zone-plate-with-apodized-aperture-for-hard-x-ray-gaussian-beam-optics
#17
Akihisa Takeuchi, Kentaro Uesugi, Yoshio Suzuki, Seiichi Itabashi, Masatoshi Oda
Fresnel zone plates with apodized apertures [apodization FZPs (A-FZPs)] have been developed to realise Gaussian beam optics in the hard X-ray region. The designed zone depth of A-FZPs gradually decreases from the center to peripheral regions. Such a zone structure forms a Gaussian-like smooth-shouldered aperture function which optically behaves as an apodization filter and produces a Gaussian-like focusing spot profile. Optical properties of two types of A-FZP, i.e. a circular type and a one-dimensional type, have been evaluated by using a microbeam knife-edge scan test, and have been carefully compared with those of normal FZP optics...
May 1, 2017: Journal of Synchrotron Radiation
https://www.readbyqxmd.com/read/28410681/simulation-of-scanner-and-patient-specific-low-dose-ct-imaging-from-existing-ct-images
#18
Robiël E Naziroglu, Vincent F van Ravesteijn, Lucas J van Vliet, Geert J Streekstra, Frans M Vos
PURPOSE: Simulating low-dose Computed Tomography (CT) facilitates in-silico studies into the required dose for a diagnostic task. Conventionally, low-dose CT images are created by adding noise to the projection data. However, in practice the raw data is often simply not available. This paper presents a new method for simulating patient-specific, low-dose CT images without the need of the original projection data. METHODS: The low-dose CT simulation method included the following: (1) computation of a virtual sinogram from a high dose CT image through a radon transform; (2) simulation of a 'reduced'-dose sinogram with appropriate amounts of noise; (3) subtraction of the high-dose virtual sinogram from the reduced-dose sinogram; (4) reconstruction of a noise volume via filtered back-projection; (5) addition of the noise image to the original high-dose image...
April 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28410283/postoperative-evaluation-of-bilateral-reading-performance-with-two-intraocular-lenses-twelve-month-results
#19
Semra Akkaya Turhan, Ebru Toker
PURPOSE: The aim of this study was to compare the bilateral reading performances within the first 12 months after the implantation of two intraocular lens (IOL) models. METHODS: The patients involved in this research had bilateral phacoemulsification and implantation of the Acriva Reviol MFM 613 IOL (group 1) or AcrySof ReSTOR SN6AD1 apodized multifocal IOL (group 2). The bilateral reading performance was evaluated preoperatively and postoperatively using the MNREAD acuity charts...
April 12, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28380916/simply-integrated-dual-comb-spectrometer-via-tunable-repetition-rates-and-avoiding-self-referencing
#20
Honglei Yang, Haoyun Wei, Kun Chen, Shengkang Zhang, Yan Li
Dual-comb system with simplified integration acts a crucial role in the next stage of field-deployable application. Here we demonstrate a home-made dual-comb spectrometer that meets this requirement based on optically stabilized erbium-fiber frequency combs. The simplified integration and operability are highlighted by the embedded large motion-span automatic optical delay line that resulted in 1.7 MHz of continuous repetition rate tuning range and avoid multiple fiber cutbacks. This relaxes the second similar frequency comb duplication, therefore simplifies dual-comb system integration...
April 3, 2017: Optics Express
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