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https://www.readbyqxmd.com/read/28092504/wall-shear-rate-measurement-validation-of-a-new-method-through-multiphysics-simulations
#1
Stefano Ricci, Abigail Swillens, Alessandro Ramalli, Patrick Segers, Piero Tortoli
Wall shear stress is known to affect the vessel endothelial function and to be related to important pathologies like the development of atherosclerosis. It is defined as the product of the blood viscosity by the blood velocity gradient at the wall position, i.e., the wall shear rate (WSR). The WSR measurement is particularly challenging in important cardiovascular sites, like the carotid bifurcation, because of the related complex flow configurations characterized by high spatial and temporal gradients, wall movement, and clutter noise...
January 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28089839/maxillary-artery-to-middle-cerebral-artery-bypass-a-novel-technique-for-exposure-of-the-maxillary-artery
#2
Kaan Yagmurlu, M Yashar S Kalani, Nikolay L Martirosyan, Sam Safavi-Abbasi, Evgenii Belykh, Avra S Laarakker, Peter Nakaji, Joseph M Zabramski, Mark C Preul, Robert F Spetzler
OBJECTIVES: Define the maxillary artery (MaxA) anatomy and present a novel technique for exposing and preparing this vessel as a bypass donor. METHODS: Cadaveric and radiological studies were used to define the MaxA anatomy and illustrate a novel method for harvesting and preparing it for extracranial-to-intracranial bypass. RESULTS: The MaxA runs parallel to the frontal branch of the superficial temporal artery (STA) and is located on average 24...
January 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28088803/small-versus-large-ruptured-intracranial-aneurysm-concerns-with-the-site-of-aneurysm
#3
Bum Joon Kim, Hyun Goo Kang, Byeong-Duk Kwun, Jae-Sung Ahn, Jisung Lee, Sung Ho Lee, Dong-Wha Kang, Jong S Kim, Sun U Kwon
BACKGROUND: Although size is one of the strongest predictors, small aneurysms often rupture. We compared the characteristics of small and large ruptured intracranial aneurysms (RIAs) according to their location to find the factors associated with small RIAs in each location. METHODS: Patients with subarachnoid hemorrhage due to saccular RIAs were consecutively enrolled. The sizes were dichotomized as small (<5 mm) or large, and the location was classified as paraclinoid-distal internal carotid artery, sidewalls of anterior or middle cerebral artery (MCA; sidewall), MCA-bifurcation, anterior or posterior communicating artery (Acom or Pcom, respectively), and posterior circulation RIAs...
January 14, 2017: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/28088146/photoinduced-c-i-bond-homolysis-of-5-iodouracil-a-singlet-predissociation-pathway
#4
Xiaojuan Dai, Di Song, Kunhui Liu, Hongmei Su
5-Iodouracil (5-IU) can be integrated into DNA and acts as a UV sensitive chromophore suitable for probing DNA structure and DNA-protein interactions based on the photochemical reactions of 5-IU. Here, we perform joint studies of time-resolved Fourier transform infrared (TR-FTIR) spectroscopy and ab initio calculations to examine the state-specific photochemical reaction mechanisms of the 5-IU. The fact that uracil (U) is observed in TR-FTIR spectra after 266 nm irradiation of 5-IU in acetonitrile and ascribed to the product of hydrogen abstraction by the uracil-5-yl radical (U·) provides experimental evidence for the C-I bond homolysis of 5-IU...
January 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28087633/the-abl-pathway-bifurcates-to-balance-enabled-and-rac-signaling-in-axon-patterning-in-drosophila
#5
Ramakrishnan Kannan, Jeong-Kuen Song, Tatiana Karpova, Akanni Clarke, Madhuri Shivalkar, Benjamin Wang, Lyudmila Kotlyanskaya, Irina Kuzina, Qun Gu, Edward Giniger
The Abl tyrosine kinase signaling network controls cell migration, epithelial organization, axon patterning and other aspects of development. While individual components are known, the relationships among them remain mysterious. We now use FRET measurements of pathway activity, analysis of protein localization and genetic epistasis to dissect the structure of this network in Drosophila We find that the adaptor protein Disabled stimulates Abl kinase activity. Abl suppresses the actin regulatory factor Enabled, and we find that Abl also acts through the GEF Trio to stimulate the signaling activity of Rac GTPase: Abl gates the activity of the spectrin repeats of Trio, allowing them to relieve intramolecular repression of Trio GEF activity by the Trio N-terminal domain...
January 13, 2017: Development
https://www.readbyqxmd.com/read/28087184/clinical-characteristics-of-ruptured-distal-middle-cerebral-artery-aneurysms-review-of-the-literature
#6
REVIEW
Keiji Tsutsumi, Tetsuyoshi Horiuchi, Alhusain Nagm, Yasuyuki Toba, Kazuhiro Hongo
Middle cerebral artery (MCA) aneurysms usually arise at the primary MCA bifurcation or trifurcation. Distal MCA aneurysms are rarely considered as sources of aneurysmal subarachnoid hemorrhage (SAH). It has been reported that ruptured distal MCA aneurysms are associated with head trauma, neoplastic emboli, arterial dissection, or bacterial infection. We experienced five cases of ruptured distal MCA aneurysms and evaluated their clinical characteristics. Retrospective analysis of aneurysmal SAH at Kobayashi Neurosurgical Neurological Hospital was performed from January, 2004 to December, 2014...
January 10, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28081099/high-order-external-cavity-modes-and-restabilization-of-a-laser-diode-subject-to-a-phase-conjugate-feedback
#7
Émeric Mercier, Lionel Weicker, Delphine Wolfersberger, Deborah M Kane, Marc Sciamanna
We experimentally report the sequence of bifurcations destabilizing and restabilizing a laser diode with phase-conjugate feedback when the feedback rate is increased. Specifically, we successively observe the initial steady state, undamped relaxation oscillations, quasi-periodicity, chaos, and oscillating solutions at harmonics up to 13 times the external cavity frequency but also the restabilization to a steady state. The experimental results are qualitatively well reproduced by a model that accounts for the time the light takes to penetrate the phase-conjugate mirror...
January 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28079613/centripetal-movement-of-the-capillaries-in-the-central-macular-region-after-internal-limiting-membrane-peeling
#8
Kazuyuki Kumagai, Masanori Hangai, Mariko Furukawa, Tetsuyuki Suetsugu, Nobuchika Ogino
PURPOSE: To report a case that showed centripetal movements of the capillaries in the central macular region after vitrectomy with internal limiting membrane peeling. METHODS: A 57-year-old pseudophakic woman underwent successful vitrectomy with internal limiting membrane peeling and air tamponade for a vitreomacular traction. Optical coherence tomography angiographic images of the 3 mm × 3 mm inner retinal vascular plexus were examined preoperatively and at 3 months postoperatively...
January 11, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28077003/influence-of-extrinsic-inputs-and-synaptic-gains-on-dynamics-of-wendling-s-neural-mass-model-a-bifurcation-analysis
#9
Shujuan Geng, Weidong Zhou
We analyze the neurodynamics attributed by a model proposed by Wendling and co-workers (2002) [Wendling, F., Bartolomei, F., Bellanger, J.J. & Chauvel, P. (2002) Epileptic fast activity can be explained by a model of impaired GABAergic dendritic inhibition. Eur. J. Neurosci., 15, 1499.] to explain several different types of electroencephalographic activities. We could find three principal types of steady states when the system parameters change slowly: (i) the model produce a constant output when it is under a state of stable equilibrium point with a constant input...
January 11, 2017: Journal of Integrative Neuroscience
https://www.readbyqxmd.com/read/28076961/total-arch-replacement-through-a-median-sternotomy-for-kommerell-s-diverticulum
#10
Yoshihiro Goto, Yutaka Koyama, Soh Hosoba, Shinji Ogawa, Shunsuke Fukaya, Yasuhide Okawa
Kommerell's diverticulum with a right aortic arch and aberrant left subclavian artery is a rare anomaly, and the optimal operative strategy has not yet been established. In particular, the approach to the diverticulum is controversial, with the greatest concern being whether or not to add a right thoracotomy to the median sternotomy for distal anastomosis. We successfully performed total arch replacement through a median sternotomy only, by referring to preoperative computed tomography. We think that if the aneurysm is in a shallow position from the tracheal bifurcation, total arch replacement is possible with a midline incision only...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/28074030/working-model-of-the-deep-relationships-of-diverse-modern-human-genetic-lineages-outside-of-africa
#11
Mark Lipson, David Reich
A major topic of interest in human prehistory is how the large-scale genetic structure of modern populations outside of Africa was established. Demographic models have been developed that capture the relationships among small numbers of populations or within particular geographical regions, but constructing a phylogenetic tree with gene flow events for a wide diversity of non-Africans remains a difficult problem. Here, we report a model that provides a good statistical fit to allele-frequency correlation patterns among East Asians, Australasians, Native Americans, and ancient western and northern Eurasians, together with archaic human groups...
January 10, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28072714/optical-coherence-tomography-assessment-of-a-complex-bifurcation-lesion-treated-with-double-kissing-crush-technique-a-case-report
#12
Jin-Zan Cai, Yao-Jun Zhang, Tian Xu, Yong-Xiang Zhu, Chen-Yu Mao, Christos V Bourantas, Tom Crake, Shao-Liang Chen
The DEFINITION (Impact of the complexity of bifurcation lesions treated with drug-eluting stents) study has provided a novel classification to evaluate the complexity of coronary bifurcation lesion according to coronary angiography, but angiographic imaging due to its low resolution and inherited limitation may result in an inaccurate adjudication.We used optical coherence tomography (OCT) to further evaluate the coronary characteristics in a patient with "simple" bifurcation lesion which was classified by the DEFINITION criteria...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28071947/presacral-abscess-as-a-rare-complication-of-sacral-nerve-stimulator-implantation
#13
A Gumber, S Ayyar, H Varia, S Pettit
A 50-year-old man with intractable anal pain attributed to proctalgia fugax underwent insertion of a sacral nerve stimulator via the right S3 vertebral foramen for pain control with good symptomatic relief. Thirteen months later, he presented with signs of sepsis. Computed tomography (CT) and magnetic resonance imaging (MRI) showed a large presacral abscess. MRI demonstrated increased enhancement along the pathway of the stimulator electrode, indicating that the abscess was caused by infection introduced at the time of sacral nerve stimulator placement...
January 10, 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28070902/a-modified-lvad-technique-to-augment-caval-and-pulmonary-arterial-blood-flow-in-the-failing-fontan-circulation
#14
Michael F Swartz, Louis DiVincenti, Karen Smith, Robin Westcott, Kevin Belmont, William Harris, Francisco Gensini, George M Alfieris
BACKGROUND: There are minimal circulatory support options for patients with a failing Fontan. The Heartmate II (HMII) left ventricular assist device (Thoratec, Bedford, MA) in its packaged state cannot augment caval/pulmonary arterial blood flow. AIM: We hypothesized that a modified HMII pump could augment caval and pulmonary arterial blood flow. METHODS: A bifurcated ringed Gore-Tex graft (W. L. Gore & Associates, Flagstaff, AZ) was sewn to the HMII inflow, and the outflow graft transected and tapered from 16 mm to 8 mm in diameter...
January 9, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28067200/quantitative-angiography-methods-for-bifurcation-lesions-a-consensus-statement-update-from-the-european-bifurcation-group
#15
Carlos Collet, Yoshinobu Onuma, Rafael Cavalcante, Maik Grundeken, Philippe Généreux, Jeffrey Popma, Ricardo Costa, Goran Stankovic, Shengxian Tu, Johan H C Reiber, Jean-Paul Aben, Jens Flensted Lassen, Yves Louvard, Alexandra Lansky, Patrick W Serruys
Bifurcation lesions represent one of the most challenging lesions subset in interventional cardiology. The European Bifurcation Club (EBC) is an academic consortium whose goal has been to assess and recommend the appropriate strategies to manage bifurcation lesions. The quantitative coronary angiography (QCA) methods for the evaluation of bifurcation lesions has been subject to extensive research. Single vessel quantitative coronary angiography (QCA) has shown to be inaccurate to assess bifurcation lesions dimensions...
January 10, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28065691/difference-in-vascular-response-between-sirolimus-eluting-and-everolimus-eluting-stents-in-ostial-left-circumflex-artery-after-unprotected-left-main-as-observed-by-optical-coherence-tomography
#16
Yusuke Fujino, Guilherme F Attizzani, Satoko Tahara, Toru Naganuma, Kensuke Takagi, Hiroto Yabushita, Wei Wang, Kentaro Tanaka, Takahiro Matsumoto, Hiroyoshi Kawamoto, Yuya Yamada, Shinnosuke Amano, Yusuke Watanabe, Takayuki Warisawa, Tomohiko Sato, Satoru Mitomo, Naoyuki Kurita, Hisaaki Ishiguro, Koji Hozawa, Takahiro Tsukahara, Masahiro Motosuke, Hiram G Bezerra, Shotaro Nakamura, Sunao Nakamura
BACKGROUND: Kissing-balloon technique (KBT) is commonly performed during percutaneous coronary intervention of distal unprotected left main coronary artery (ULM) aiming at obtaining optimal opening of the side branch (left circumflex artery; LCX) ostium. Nonetheless, detailed evaluation of vascular response to stents in LCX ostium is lacking. We therefore evaluated the vascular response to different drug-eluting stents (DES) in ostial LCX after ULM by means of optical coherence tomography (OCT)...
December 23, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28063427/hydrogen-bond-breaking-dynamics-in-the-water-pentamer-terahertz-vrt-spectroscopy-of-a-20-%C3%AE-m-libration
#17
William T S Cole, Raymond S Fellers, Mark R Viant, Richard J Saykally
Hydrogen bonds in solid and liquid water are formed and broken via librational vibrations, hence characterizing the details of these motions is vital to understanding these important dynamics. Here we report the measurement and assignment of 875 transitions comprising 6 subbands originating from out-of-plane librational transitions of the water pentamer-d10 near 512 cm(-1). The precisely measured (ca. 1 ppm) transitions reveal bifurcation splittings of ∼1884 MHz, a ∼4000× enhancement over ground state splittings and 100× greater than predicted by theory...
January 7, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28062986/the-psilostomidae-looss-1900-sensu-stricto-digenea-echinostomatoidea-description-of-three-new-genera-and-a-key-to-the-genera-of-the-family
#18
Olena Kudlai, Aneta Kostadinova, Eric E Pulis, Vasyl V Tkach
Three new psilostomid genera, Byrdtrema n. g., Longisaccus n. g. and Macracetabulum n. g., each with a single species, are described from ducks, Aix sponsa (L.) and Bucephala albeola (L.) in North America. Byrdtrema n. g. and Macracetabulum n. g. possess a bipartite seminal vesicle and share this character with four psilostomid genera, Grysoma Byrd, Bogitsh & Maples, 1961, Neopsilotrema Kudlai, Pulis, Kostadinova & Tkach, 2016, Psilostomum Looss, 1899 and Psilotornus Byrd & Prestwood, 1969. Byrdtrema n. g. differs from Macracetabulum n...
January 2017: Systematic Parasitology
https://www.readbyqxmd.com/read/28062892/a-bifurcation-theorem-for-evolutionary-matrix-models-with-multiple-traits
#19
J M Cushing, F Martins, A A Pinto, Amy Veprauskas
One fundamental question in biology is population extinction and persistence, i.e., stability/instability of the extinction equilibrium and of non-extinction equilibria. In the case of nonlinear matrix models for structured populations, a bifurcation theorem answers this question when the projection matrix is primitive by showing the existence of a continuum of positive equilibria that bifurcates from the extinction equilibrium as the inherent population growth rate passes through 1. This theorem also characterizes the stability properties of the bifurcating equilibria by relating them to the direction of bifurcation, which is forward (backward) if, near the bifurcation point, the positive equilibria exist for inherent growth rates greater (less) than 1...
January 6, 2017: Journal of Mathematical Biology
https://www.readbyqxmd.com/read/28061486/superficial-temporal-artery-sparing-mini-pterional-approach-for-cerebral-aneurysm-surgery
#20
Jun-Young Ahn, Sung-Tae Kim, Ki-Chang Yi, Won-Hee Lee, Sung Hwa Paeng, Young-Gyun Jeong
OBJECTIVE: The purposes of this study were to introduce a superficial temporal artery (STA)-sparing mini-pterional approach for the treatment of cerebral aneurysms and review the surgical results of this approach. METHODS: Between June 2010 and December 2015, we performed the STA-sparing mini-pterional approach for 117 patients with 141 unruptured intracranial aneurysms. We analyzed demographic, radiologic, and clinical variables including age, sex, craniotomy size, aneurysm location, height of STA bifurcation, and postoperative complications...
January 1, 2017: Journal of Korean Neurosurgical Society
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