keyword
MENU ▼
Read by QxMD icon Read
search

Grid Cell

keyword
https://www.readbyqxmd.com/read/28212563/progression-of-motor-deficits-in-glioma-bearing-mice-impact-of-cnf1-therapy-at-symptomatic-stages
#1
Eleonora Vannini, Federica Maltese, Francesco Olimpico, Alessia Fabbri, Mario Costa, Matteo Caleo, Laura Baroncelli
Glioblastoma (GBM) is the most aggressive type of brain tumor. In this context, animal models represent excellent tools for the early detection and longitudinal mapping of neuronal dysfunction, that are critical in the preclinical validation of new therapeutic strategies. In a mouse glioma model, we developed sensitive behavioral readouts that allow early recognizing and following neurological symptoms. We injected GL261 cells into the primary motor cortex of syngenic mice and we used a battery of behavioral tests to longitudinally monitor the dysfunction induced by tumor growth...
February 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28199875/examining-the-impacts-of-increased-corn-production-on-groundwater-quality-using-a-coupled-modeling-system
#2
Valerie Garcia, Ellen Cooter, James Crooks, Brian Hinckley, Mark Murphy, Xiangnan Xing
This study demonstrates the value of a coupled chemical transport modeling system for investigating groundwater nitrate contamination responses associated with nitrogen (N) fertilizer application and increased corn production. The coupled Community Multiscale Air Quality Bidirectional and Environmental Policy Integrated Climate modeling system incorporates agricultural management practices and N exchange processes between the soil and atmosphere to estimate levels of N that may volatilize into the atmosphere, re-deposit, and seep or flow into surface and groundwater...
February 12, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28185453/modification-of-the-highly-conductive-pedot-pss-layer-for-use-in-silver-nanogrid-electrodes-for-flexible-inverted-polymer-solar-cells
#3
Jie Wang, Fei Fei, Qun Luo, Shuhong Nie, Na Wu, Xiaolian Chen, Wenming Su, Yuanjie Li, Chang-Qi Ma
Silver nano-grid based flexible transparent electrode is recognized as the most promising alternative to ITO electrode for organic electronics, owing to its low production cost and excellent flexibility. Typically, high conductive thin film coating layer, such as high conductive PEDOT:PSS (HC-PEDOT:PSS) is usually deposited onto the Ag-grid electrode to smooth the surface and to minimize the sheet resistance. In this paper, we found that inverted flexible polymer solar cells with structure of Ag-grid/HC-PEDOT:PSS/ZnO/photoactive layer/MoO3/Al generally exhibits strong S-shaped J-V curves, which could be eliminated by light-soaking treatment...
February 10, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28185275/surface-markers-for-guiding-cylindrical-diffuser-fiber-insertion-in-interstitial-photodynamic-therapy-of-head-and-neck-cancer
#4
Emily Oakley, David A Bellnier, Alan Hutson, Brian Wrazen, Hassan Arshad, Harry Quon, Gal Shafirstein
BACKGROUND AND OBJECTIVES: Image-based treatment planning can be used to compute the delivered light dose during interstitial photodynamic therapy (I-PDT) of locally advanced head and neck squamous cell carcinoma (LA-HNSCC). The objectives of this work were to evaluate the use of surface fiducial markers and flexible adhesive grids in guiding interstitial placement of laser fibers, and to quantify the impact of discrepancies in fiber location on the expected light dose volume histograms (DVHs)...
February 10, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28178279/snow-leopard-and-himalayan-wolf-food-habits-and-prey-selection-in-the-central-himalayas-nepal
#5
Madhu Chetri, Morten Odden, Per Wegge
Top carnivores play an important role in maintaining energy flow and functioning of the ecosystem, and a clear understanding of their diets and foraging strategies is essential for developing effective conservation strategies. In this paper, we compared diets and prey selection of snow leopards and wolves based on analyses of genotyped scats (snow leopards n = 182, wolves n = 57), collected within 26 sampling grid cells (5×5 km) that were distributed across a vast landscape of ca 5000 km2 in the Central Himalayas, Nepal...
2017: PloS One
https://www.readbyqxmd.com/read/28177578/feasibility-of-a-supporting-salt-free-non-aqueous-redox-flow-battery-utilizing-ionic-active-materials
#6
Jarrod Milshtein, Sydney Fisher, Tanya Breault, Levi Thompson, Fikile Brushett
Non-aqueous redox flow batteries (NAqRFBs) are promising devices for grid-scale energy storage, however, high projected prices could limit commercial prospects. One price reduction route is to minimize or eliminate the expensive supporting salts typically employed in NAqRFBs. We demonstrate the feasibility of a flow cell operating in the absence of supporting salt, utilizing ionic active species. These ionic species possess high conductivities in acetonitrile (12 - 19 mS cm-1), and cycle at 20 mA cm-2 with energy efficiencies (> 75%) comparable to state-of-the-art NAqRFBs employing high concentrations of supporting salt...
February 8, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28173628/designing-ecological-climate-change-impact-assessments-to-reflect-key-climatic-drivers
#7
Helen R Sofaer, Joseph J Barsugli, Catherine S Jarnevich, John T Abatzoglou, Marian K Talbert, Brian W Miller, Jeffrey T Morisette
Identifying the climatic drivers of an ecological system is a key step in assessing its vulnerability to climate change. The climatic dimensions to which a species or system is most sensitive - such as means or extremes - can guide methodological decisions for projections of ecological impacts and vulnerabilities. However, scientific workflows for combining climate projections with ecological models have received little explicit attention. We review Global Climate Model (GCM) performance along different dimensions of change and compare frameworks for integrating GCM output into ecological models...
February 7, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28165079/a-review-of-high-temperature-co-electrolysis-of-h2o-and-co2-to-produce-sustainable-fuels-using-solid-oxide-electrolysis-cells-soecs-advanced-materials-and-technology
#8
REVIEW
Yun Zheng, Jianchen Wang, Bo Yu, Wenqiang Zhang, Jing Chen, Jinli Qiao, Jiujun Zhang
High-temperature solid oxide electrolysis cells (SOECs) are advanced electrochemical energy storage and conversion devices with high conversion/energy efficiencies. They offer attractive high-temperature co-electrolysis routes that reduce extra CO2 emissions, enable large-scale energy storage/conversion and facilitate the integration of renewable energies into the electric grid. Exciting new research has focused on CO2 electrochemical activation/conversion through a co-electrolysis process based on the assumption that difficult C[double bond, length as m-dash]O double bonds can be activated effectively through this electrochemical method...
February 6, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/28161726/medial-entorhinal-cortex-and-medial-septum-contribute-to-self-motion-based-linear-distance-estimation
#9
Pierre-Yves Jacob, Marta Gordillo-Salas, Justine Facchini, Bruno Poucet, Etienne Save, Francesca Sargolini
Path integration is a navigation strategy that requires animals to integrate self-movements during exploration to determine their position in space. The medial entorhinal cortex (MEC) has been suggested to play a pivotal role in this process. Grid cells, head-direction cells, border cells as well as speed cells within the MEC collectively provide a dynamic representation of the animal position in space based on the integration of self-movements. All these cells are strongly modulated by theta oscillations, thus suggesting that theta rhythmicity in the MEC may be essential for integrating and coordinating self-movement information during navigation...
February 4, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28157163/transmission-electron-microscopy-of-xdr-mycobacterium-tuberculosis-isolates-grown-on-high-dose-of-o%C3%AF-oxacin
#10
Mohammad Arjomandzadegan, Maryam Sadrnia, Leonid Titov, Larissa Surkova, Hossein Sarmadian, Reza Ghasemikhah, Hossein Hosseiny
The aim of the study was to investigate behavior of resistant Mycobacterium tuberculosis (MTB) isolates under a high dose of ofloxacin and its morphological changes. 19 extensively drug resistant (XDR) clinical isolates of MTB were grown on Löwenstein-Jensen medium containing progressively increasing concentrations of ofloxacin (2, 4, 8, 16, 32 mg/L). Ultra-structure analyses of resistant isolates grown on ofloxacin were conducted by transmission electron microscopy (TEM). Fixation was carried out by 4% glutaraldehyde in 0...
February 2, 2017: Scientia Pharmaceutica
https://www.readbyqxmd.com/read/28147560/experiments-on-the-low-frequency-barrier-characteristics-of-cellular-metamaterial-panels-in-a-diffuse-sound-field
#11
Srinivas Varanasi, J Stuart Bolton, Thomas Siegmund
The metamaterial under investigation here consists of a periodic arrangement of unit plates in a grid-like frame such that there is a contrast in the local areal mass between cell interior and cell wall. In the low frequency range and under normal incidence this metamaterial panel exhibits a sound transmission loss significantly larger than the transmission loss of an unstructured panel with the same homogeneous mass per unit area. However, when the incident sound field is diffuse, the relative advantage of the metamaterial barrier is reduced or eliminated...
January 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28142317/inventing-atomic-resolution-scanning-dielectric-microscopy-to-see-a-single-protein-complex-operation-live-at-resonance-in-a-neuron-without-touching-or-adulterating-the-cell
#12
Lokesh Agrawal, Satyajit Sahu, Subrata Ghosh, Takashi Shiga, Daisuke Fujita, Anirban Bandyopadhyay
A substantial ion flow in a normally wet protein masks any other forms of signal transmission. We use hysteresis and linear conduction (both are artifacts) as a marker to precisely wet a protein, which restricts the ionic conduction (hysteresis disappears), and at the same time, it is not denatured (quantized conductance and Raman spectra are intact). Pure electric visualization of proteins at work by eliminating the screening of ions, electrons, would change the way we study biology. Here we discuss the technical challenges resolved for imaging a protein or live cell using nonlinear dielectric response (spatial distribution of conductance, capacitance and phase, GCP trio)...
January 31, 2017: Journal of Integrative Neuroscience
https://www.readbyqxmd.com/read/28142123/plasmonic-nanocarrier-grid-enhanced-raman-sensor-for-studies-of-anticancer-drug-delivery
#13
Katarzyna Kurzątkowska, Ty Santiago, Maria Hepel
Targeted drug delivery systems using nanoparticle nanocarriers offer remarkable promise for cancer therapy by discriminating against devastating cytotoxicity of chemotherapeutic drugs to healthy cells. To aid in the development of new drug nanocarriers, we propose a novel plasmonic nanocarrier grid-enhanced Raman sensor which can be applied for studies and testing of drug loading onto the nanocarriers, attachment of targeting ligands, dynamics of drug release, assessment of nanocarrier stability in biological environment, and general capabilities of the nanocarrier...
January 24, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28129162/memory-efficient-on-the-fly-voxelization-and-rendering-of-particle-data
#14
Tobias Zirr, Carsten Dachsbacher
In this paper we present a novel GPU-friendly real-time voxelization technique for rendering homogeneous media that is defined by particles, e.g. fluids obtained from particle-based simulations such as Smoothed Particle Hydrodynamics (SPH). Our method computes view-adaptive binary voxelizations with on-the-fly compression of a tiled perspective voxel grid, achieving higher resolutions than previous approaches. It allows for interactive generation of realistic images, enabling advanced rendering techniques such as ray casting-based refraction and reflection, light scattering and absorption, and ambient occlusion...
January 23, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28122050/research-on-grid-size-suitability-of-gridded-population-distribution-in-urban-area-a-case-study-in-urban-area-of-xuanzhou-district-china
#15
Nan Dong, Xiaohuan Yang, Hongyan Cai, Fengjiao Xu
The research on the grid size suitability is important to provide improvement in accuracies of gridded population distribution. It contributes to reveal the actual spatial distribution of population. However, currently little research has been done in this area. Many well-modeled gridded population dataset are basically built at a single grid scale. If the grid cell size is not appropriate, it will result in spatial information loss or data redundancy. Therefore, in order to capture the desired spatial variation of population within the area of interest, it is necessary to conduct research on grid size suitability...
2017: PloS One
https://www.readbyqxmd.com/read/28113769/a-combined-eulerian-lagrangian-data-representation-for-large-scale-applications
#16
Franz Sauer, Jinrong Xie, Kwan-Liu Ma
The Eulerian and Lagrangian reference frames each provide a unique perspective when studying and visualizing results from scientific systems. As a result, many large-scale simulations produce data in both formats, and analysis tasks that simultaneously utilize information from both representations are becoming increasingly popular. However, due to their fundamentally different nature, drawing correlations between these data formats is a computationally difficult task, especially in a large-scale setting. In this work, we present a new data representation which combines both reference frames into a joint Eulerian-Lagrangian format...
October 25, 2016: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28112408/mammographic-evidence-of-microenvironment-changes-in-tumorous-breasts
#17
Zach Marin, Kendra A Batchelder, Brian C Toner, Lyne Guimond, Evgeniya Gerasimova-Chechkina, Amy R Harrow, Alain Arneodo, Andre Khalil
PURPOSE: The microenvironment of breast tumors plays a critical role in tumorigenesis. As long as the structural integrity of the microenvironment is upheld, the tumor is suppressed. If tissue structure is lost through disruptions in the normal cell cycle, the microenvironment may act as a tumor promoter. Therefore, the properties that distinguish between healthy and tumorous tissue may not be solely in the tumor characteristics but rather in surrounding non-tumor tissue. The goal of this paper is to show preliminary evidence that tissue disruption and loss of homeostasis in breast tissue microenvironment and breast bilateral asymmetry can be quantitatively and objectively assessed from mammography via a localized, wavelet-based analysis of the whole breast...
January 23, 2017: Medical Physics
https://www.readbyqxmd.com/read/28111080/tau-pathology-induces-excitatory-neuron-loss-grid-cell-dysfunction-and-spatial-memory-deficits-reminiscent-of-early-alzheimer-s-disease
#18
Hongjun Fu, Gustavo A Rodriguez, Mathieu Herman, Sheina Emrani, Eden Nahmani, Geoffrey Barrett, Helen Y Figueroa, Eliana Goldberg, S Abid Hussaini, Karen E Duff
The earliest stages of Alzheimer's disease (AD) are characterized by the formation of mature tangles in the entorhinal cortex and disorientation and confusion when navigating familiar places. The medial entorhinal cortex (MEC) contains specialized neurons called grid cells that form part of the spatial navigation system. Here we show in a transgenic mouse model expressing mutant human tau predominantly in the EC that the formation of mature tangles in old mice was associated with excitatory cell loss and deficits in grid cell function, including destabilized grid fields and reduced firing rates, as well as altered network activity...
February 8, 2017: Neuron
https://www.readbyqxmd.com/read/28096653/applicability-of-automatic-spectral-domain-optical-coherence-tomography-for-glaucoma-mass-screening
#19
Tadashi Nakano, Takeshi Hayashi, Toru Nakagawa, Toru Honda, Satoshi Owada, Hitoshi Endo, Masayuki Tatemichi
PURPOSE: To perform a preliminary evaluation of the applicability of automatic spectral domain optical coherence tomography (ASD-OCT) for glaucoma mass screening in a population-based setting. METHODS: Information using ASD-OCT (thicknesses of the macular retinal nerve fiber layer [mRNFL], disc retinal nerve fiber layer [dRNFL], ganglion cell layer [GCL] + inner plexiform layer [IPL]; GCL+, and ganglion cell complex [GCL + IPL + RNFL; GCL++]) was obtained from 245 eyes of 123 glaucomatous subjects and 1,454 eyes of 727 normal subjects...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28077334/the-neuroprotective-compound-p7c3-a20-promotes-neurogenesis-and-improves-cognitive-function-after-ischemic-stroke
#20
Zachary B Loris, Andrew A Pieper, W Dalton Dietrich
Ischemic stroke is a devastating condition with few therapeutic interventions available. The neuroprotective compound P7C3-A20 inhibits mature neuronal cell death while also increasing the net magnitude of postnatal neurogenesis in models of neurodegeneration and acute injury. P7C3 compounds enhance flux of nicotinamide adenine dinucleotide (NAD) in mammalian cells, a proposed therapeutic approach to treating cerebral ischemia. The effectiveness of P7C3-A20 treatment on chronic histopathological and behavioral outcomes and neurogenesis after ischemic stroke has not previously been established...
January 8, 2017: Experimental Neurology
keyword
keyword
71545
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"