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https://www.readbyqxmd.com/read/27789587/expression-of-mir-18a-and-mir-210-in-normal-breast-tissue-as-candidate-biomarkers-of-breast-cancer-risk
#1
Ali Shidfar, Fabricio F Costa, Denise M Scholtens, Jared M Bischof, Megan E Sullivan, David Ivancic, Elio F Vanin, Marcelo B Soares, Jun Wang, Seema A Khan
miRNAs are non-coding RNAs with abnormal expression in breast cancer (BC); their expression in high-risk benign breast tissue may relate to BC risk. We examined miRNA profiles in contralateral unaffected breasts (CUBs) of BC patients and validated resulting candidates in two additional sample sets. Expression profiles of 754 mature miRNAs were examined using TaqMan Low Density Arrays in 30 BC samples (15 ER-positive and 15 ER-negative) and paired CUBs; and 15 reduction mammoplasty (RM) controls. Pairwise comparisons identified miRNAs with significantly differential expression...
October 27, 2016: Cancer Prevention Research
https://www.readbyqxmd.com/read/27658592/antiplasmodial-and-cytotoxic-activities-of-toad-venoms-from-southern-amazon-brazil
#2
Felipe Finger Banfi, Karla de Sena Guedes, Carla Regina Andrighetti, Ana Carolina Aguiar, Bryan Wender Debiasi, Janaina da Costa Noronha, Domingos de Jesus Rodrigues, Gerardo Magela Vieira Júnior, Bruno Antonio Marinho Sanchez
The drug-resistance of malaria parasites is the main problem in the disease control. The huge Brazilian biodiversity promotes the search for new compounds, where the animal kingdom is proving to be a promising source of bioactive compounds. The main objective of this study was to evaluate the antiplasmodial and cytotoxic activity of the compounds obtained from the toad venoms of Brazilian Amazon. Toad venoms were collected from the secretion of Rhinella marina and Rhaebo guttatus in Mato Grosso State, Brazil...
August 2016: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/27462729/biofilm-formation-and-disinfectant-susceptibility-of-persistent-and-nonpersistent-listeria-monocytogenes-isolates-from-gorgonzola-cheese-processing-plants
#3
Annalisa Costa, Luigi Bertolotti, Luisa Brito, Tiziana Civera
The aim of this study was to investigate whether the biofilm-forming ability and/or the disinfectant susceptibility accounted for the persistence of Listeria monocytogenes in Gorgonzola cheese processing plants. For this purpose, a set of 16 L. monocytogenes isolates collected in the 2004-2007 period was analyzed, including 11 persistent isolates collected in different years, within the collection period, and displaying identical or highly correlated pulsotypes. The evaluation of biofilm-forming ability was assessed using crystal violet (CV) staining and the enumeration of viable cells on stainless steel coupons (SSC)...
July 27, 2016: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/27449842/periodontitis-may-be-associated-with-gestational-diabetes-mellitus-but-not-affirmatively
#4
Hong Jiang, Xu Xiong
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Association Between Periodontitis and Gestational Diabetes Mellitus: Systematic Review and Meta-Analysis. Esteves Lima RP, es Cyrino RM, Dutra BC, da Silveira JO, Martins CC, Cota LOM, Costa FO. J Periodontol 2016;87(1):48-57. SOURCE OF FUNDING: The research was supported by the Coordination for the Improvement of Higher Education Personnel (CAPES, Brazil), the Minas Gerais State Research Foundation (FAPEMIG, Brazil), the National Council of Scientific and Technological Development (CNPq, Brazil), and the Dean of Research from the Federal University of Minas Gerais (PRPq/UFMG, Brazil) TYPE OF STUDY/DESIGN: Systematic review with meta-analysis...
June 2016: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/27206999/push-out-bond-strength-of-glass-fiber-posts-cemented-in-weakened-roots-with-different-luting-agents
#5
Daniele M da Silveira-Pedrosa, Luis Rm Martins, Mário Ac Sinhoreti, Lourenço Correr-Sobrinho, Manoel D Sousa-Neto, Edson D Costa, Celso de F Pedrosa-Filho, Jacy Ribeiro de Carvalho
AIM: To evaluate the push-out bond strength (BS) of direct anatomic posts (DAPs) and conventional fiber posts (CFPs) cemented with different luting agents in different thirds of flared root canals. MATERIALS AND METHODS: A total of 60 human single-rooted canine teeth were transversally sectioned 16 mm from the radicular apex. After endodontic treatment, canals were flared with diamond burs. Samples were divided into six groups according to post type and luting agent: DAP and RelyX U100 (RXU); DAP and RelyX ARC (RXA); DAP and RelyX Luting 2 (RXL); CFP and RXU; CFP and RXA; CFP and RXL...
2016: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/26529399/anthocyanin-extraction-from-plant-tissues-a-review
#6
S Silva, Em Costa, C Calhau, Rm Morais, Me Pintado
Anthocyanins have gathered the attention of the scientific community mostly due to their vast range of possible applications. They have been the center point of the research in many different fields, among which is food development, where their innate coloring, antioxidant capacity and biological potential open interesting venues to the development of new food additives and functional foodstuffs. As the range of application grows, so does the necessity to obtain these compounds and since they are naturally occurring, the most common way to obtain anthocyanins is to extract them from different plant sources, such as fruits and flowers...
November 3, 2015: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/25982537/impact-of-physical-resistance-training-on-the-sexual-function-of-women-with-polycystic-ovary-syndrome
#7
Lúcia Alves Silva Lara, Fabiene Karine Piccki Ramos, Gislaine Satiko Kogure, Rafael Silva Costa, Marcos Felipe Silva de Sá, Rui Alberto Ferriani, Rosana Maria dos Reis
INTRODUCTION: There is a need for specific measures to address overall care in women with polycystic ovary syndrome (PCOS). Physical resistance training (PRT) has been shown to improve certain body parameters. However, the effect of PRT on the sexual function of PCOS women has not been evaluated. AIM: The study aimed to assess sexual function and emotional status of PCOS women after 16 weeks of PRT. METHODS: This case-control study involved 43 women with PCOS and 51 control ovulatory women, aged 18-37 years...
July 2015: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/25964821/acute-effects-of-different-stretching-techniques-on-the-number-of-repetitions-in-a-single-lower-body-resistance-training-session
#8
Marcos A Sá, Gabriel R Neto, Pablo B Costa, Thiago M Gomes, Cláudio M Bentes, Amanda F Brown, Jefferson S Novaes
This study aimed to investigate the acute effects of passive static and ballistic stretching on maximal repetition performance during a resistance training session (RTS). Nine male subjects underwent three experimental conditions: ballistic stretching (BS); passive static stretching (PSS); and a specific warm-up (SW). The RTS was composed of three sets of 12RM for the following exercises: leg press 45 (LP), leg extension (LE), leg curl (LC), and plantar flexors (PF). Performance of six sessions was assessed 48 hours apart...
March 29, 2015: Journal of Human Kinetics
https://www.readbyqxmd.com/read/25794044/high-volume-resistance-training-reduces-postprandial-lipaemia-in-postmenopausal-women
#9
Cleiton Silva Correa, Bruno Costa Teixeira, Roberto Carlos Rebolledo Cobos, Rodrigo Cauduro Oliveira Macedo, Renata Lopes Kruger, Randall Bruce Kreismann Carteri, Régis Radaelli, Julia Silveira Gross, Ronei Silveira Pinto, Álvaro Reischak-Oliveira
The aim of this study was to compare the effects of 11 weeks of low-volume resistance training (LVRT) and high-volume resistance training (HVRT) on muscle strength, muscle thickness (MT), and postprandial lipaemia (PPL) in postmenopausal women. Thirty-six healthy and untrained postmenopausal women (age, 58.9 ± 5.8 years; 68.6 ± 10.3 kg; and BMI, 26.9 ± 4.8 kg · m(-2)) participated in resistance training 3× per week for 11 weeks (HVRT = 12; LVRT = 13; and control group = 11). Biochemical variables, both pretraining and post-training, were evaluated 16 h after the administration of an oral fat tolerance test (OFTT) and metabolic variable during [energy expenditure (EE)] and after training session [excess postexercise oxygen consumption (EPOC)]...
2015: Journal of Sports Sciences
https://www.readbyqxmd.com/read/25430509/women-with-polycystic-ovary-syndrome-have-greater-muscle-strength-irrespective-of-body-composition
#10
Gislaine Satyko Kogure, Rafael Costa Silva, Fabiene K Picchi Ramos, Cristiana Libardi Miranda-Furtado, Lucia Alves da Silva Lara, Rui Alberto Ferriani, Rosana Maria Dos Reis
The aim of this study was to compare metabolic parameters, body composition (BC) and muscle strength of women with and without polycystic ovary syndrome (PCOS). This was a case-control study that evaluated 40 women with PCOS and 40 controls. Androgens and insulin resistance were measured. BC was based on dual-energy X-ray absorptiometry. Isometric handgrip and maximal dynamic muscle strength (1-RM) strength tests were performed. Median total testosterone (p < 0.01), free androgen index (p < 0...
March 2015: Gynecological Endocrinology
https://www.readbyqxmd.com/read/25374813/prostatic-surgery-associated-acute-kidney-injury
#11
REVIEW
Elerson Carlos Costalonga, Verônica Torres Costa E Silva, Renato Caires, James Hung, Luis Yu, Emmanuel A Burdmann
Acute kidney injury (AKI) is associated with extended hospital stays, high risks of in-hospital and long-term mortality, and increased risk of incident and progressive chronic kidney disease. Patients with urological diseases are a high-risk group for AKI owing to the coexistence of obstructive uropathy, older age, and preexistent chronic kidney disease. Nonetheless, precise data on the incidence and outcomes of postoperative AKI in urological procedures are lacking. Benign prostatic hyperplasia and prostate cancer are common diagnoses in older men and are frequently treated with surgical procedures...
November 6, 2014: World Journal of Nephrology
https://www.readbyqxmd.com/read/24518317/development-of-an-orange-juice-in-house-reference-material-and-its-application-to-guarantee-the-quality-of-vitamin-c-determination-in-fruits-juices-and-fruit-pulps
#12
A Valente, A Sanches-Silva, T G Albuquerque, H S Costa
Reference materials are useful for the quality control of analytical procedures and to evaluate the performance of laboratories. There are few and expensive certified reference materials commercially available for vitamin C or ascorbic acid analysis in food matrices. In this study, the preparation and the suitability assessment of an orange juice in-house reference material (RM) for vitamin C analysis in fruits, juices and in fruit pulps is described. This RM was used for the development and full validation of an HPLC method...
July 1, 2014: Food Chemistry
https://www.readbyqxmd.com/read/24256097/amlodipine-reduces-blood-pressure-during-dynamic-resistance-exercise-in-hypertensive-patients
#13
RANDOMIZED CONTROLLED TRIAL
D R Souza, R S Gomides, L A R Costa, A C C Queiroz, S Barros, K C Ortega, D Mion, T Tinucci, C L M Forjaz
This study investigated the effect of the dihydropyridine calcium channel antagonist, amlodipine, on blood pressure (BP) during resistance exercise performed at different intensities in hypertensives. Eleven hypertensives underwent 4 weeks of placebo and amlodipine (random double-blinded crossover design). In each phase, they performed knee extension exercise until exhaustion following three protocols: one set at 100% of 1 RM (repetition maximum), three sets at 80% of 1 RM, and three sets at 40% of 1 RM. Intraarterial BP was measured before and during exercise...
February 2015: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/23965236/the-monitoring-resynchronization-devices-and-cardiac-patients-more-care-randomized-controlled-trial-phase-1-results-on-dynamics-of-early-intervention-with-remote-monitoring
#14
RANDOMIZED CONTROLLED TRIAL
Giuseppe Boriani, Antoine Da Costa, Renato Pietro Ricci, Aurelio Quesada, Stefano Favale, Saverio Iacopino, Francesco Romeo, Arnaldo Risi, Lorenza Mangoni di S Stefano, Xavier Navarro, Mauro Biffi, Massimo Santini, Haran Burri
BACKGROUND: Remote monitoring (RM) in patients with advanced heart failure and cardiac resynchronization therapy defibrillators (CRT-D) may reduce delays in clinical decisions by transmitting automatic alerts. However, this strategy has never been tested specifically in this patient population, with alerts for lung fluid overload, and in a European setting. OBJECTIVE: The main objective of Phase 1 (presented here) is to evaluate if RM strategy is able to reduce time from device-detected events to clinical decisions...
August 21, 2013: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/23528424/oxidovanadium-iv-and-dioxidovanadium-v-complexes-of-tridentate-salicylaldehyde-semicarbazones-searching-for-prospective-antitrypanosomal-agents
#15
Mariana Fernández, Lorena Becco, Isabel Correia, Julio Benítez, Oscar E Piro, Gustavo A Echeverria, Andrea Medeiros, Marcelo Comini, María Laura Lavaggi, Mercedes González, Hugo Cerecetto, Virtudes Moreno, Joao Costa Pessoa, Beatriz Garat, Dinorah Gambino
As a contribution to the identification of the relevant species for biological activity and the understanding of structure-activity relationships of [V(IV)O(L-2H)(NN)] antitrypanosomal complexes (NN is a bidentate polypyridyl DNA intercalator; L is a tridentate salicylaldehyde semicarbazone derivative), new [V(V)O2(L-2H)] complexes and [V(IV)O(L-2H)(NN)] complexes including bipy or dppz (dipyrido[3,2-a: 2',3'-c]phenazine) co-ligands are prepared and characterized in the solid state and in solution. Their activity is evaluated on Trypanosoma cruzi...
October 2013: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/23481303/toxicity-and-sublethal-effects-of-seven-insecticides-to-eggs-of-the-flower-bug-orius-insidiosus-say-hemiptera-anthocoridae
#16
Valéria Fonseca Moscardini, Pablo da Costa Gontijo, Geraldo Andrade Carvalho, Rodrigo Lopes de Oliveira, Jader Braga Maia, Fernanda Fonseca e Silva
The predatory bug Orius insidiosus is an important biological control agent of several insect pests, and is one of the most commonly used species in biological control programs worldwide. This study assessed the lethal and sublethal effects of insecticides on this species through life table, and classified the insecticides according to the definitions of toxicity given by the International Organization for Biological and Integrated Control of Noxious Animals and Plants (IOBC). A bioassay was carried out using a completely randomized design with eight treatments and 40 replicates...
July 2013: Chemosphere
https://www.readbyqxmd.com/read/23306223/influence-of-alloy-microstructure-on-the-microshear-bond-strength-of-basic-alloys-to-a-resin-luting-cement
#17
José Bauer, José Ferreira Costa, Ceci Nunes Carvalho, Douglas Nesadal de Souza, Alessandro Dourado Loguercio, Rosa Helena Miranda Grande
The aim of this study was to evaluate the influence of microstructure and composition of basic alloys on their microshear bond strength (µSBS) to resin luting cement. The alloys used were: Supreme Cast-V (SC), Tilite Star (TS), Wiron 99 (W9), VeraBond II (VBII), VeraBond (VB), Remanium (RM) and IPS d.SIGN 30 (IPS). Five wax patterns (13 mm in diameter and 4mm height) were invested, and cast in a centrifugal casting machine for each basic alloy. The specimens were embedded in resin, polished with a SiC paper and sandblasted...
2012: Brazilian Dental Journal
https://www.readbyqxmd.com/read/23175179/cardiac-work-remains-high-after-strength-exercise-in-elderly
#18
RANDOMIZED CONTROLLED TRIAL
A C C Queiroz, H Kanegusuku, M R Chehuen, L A R Costa, L F Wallerstein, V J Dias da Silva, M T Mello, C Ugrinowitsch, C L M Forjaz
Moderate- to high-intensity strength training is recommended for healthy adults. In young subjects, a single session of strength training decreases blood pressure, while heart rate and cardiac work remain elevated afterwards. However, these effects have not been clearly demonstrated in elderly subjects. To investigate this issue, 16 elderly subjects each underwent a Control and an Exercise (3 sets, 8 RM, 9 exercises) session conducted in random order. Haemodynamic variables and heart rate variability were measured before and after the interventions...
May 2013: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/22987612/responsiveness-of-hepatic-and-cerebral-cytochrome-p450-in-rat-offspring-prenatally-and-lactationally-exposed-to-a-reconstituted-pcb-mixture
#19
Patrizia Bonfanti, Francesca Comelli, Laura Assi, Lavinia Casati, Alessandra Colciago, Sara Villa, Angela Santagostino, Barbara Costa, Anita Colombo
Perinatal polychlorinated biphenyl (PCB) exposures still remain a serious health concern because offspring receive PCB burden from mother during vulnerable processes of development. Since cytochrome P450 (CYP) represents a toxicological endpoint, in the present study, representing an extended investigation of a previous multitasked one, we explored the long-term responsiveness of CYP1A and CYP2B isoforms by Western blot analysis in liver and whole brain of lactating (PN12), weaning (PN21), and adult offspring (PN60) rats prenatally and lactationally exposed to a reconstituted PCB mixture (RM) of noncoplanar PCB138, 153, 180, and coplanar PCB126 congeners...
August 2014: Environmental Toxicology
https://www.readbyqxmd.com/read/22801513/effects-of-strength-and-flexibility-training-on-functional-performance-of-healthy-older-people
#20
Rafaella R Locks, Tatiana C Costa, Soraia Koppe, Anelize M Yamaguti, Maurício C Garcia, Anna R S Gomes
OBJECTIVE: To evaluate the effects of stretching and/or resistive exercise, followed by detraining, on the functional status of older people. METHODS: Forty-five subjects were divided into four groups: control (CG; n=13; 66±6 years), stretching (SG; n=10; 69±6 years), resistive exercise (RG; n=13; 69±5 years), and resistive exercise and stretching (RSG; n=9; 66±5 years). The CG did not perform any exercise. The SG, RG, and RSG had warm-up sessions prior to performing lower-body exercises twice a week...
June 2012: Revista Brasileira de Fisioterapia
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