keyword
https://read.qxmd.com/read/33833697/therapy-processes-associated-with-sudden-gains-in-cognitive-therapy-for-depression-exploring-therapeutic-changes-in-the-sessions-surrounding-the-gains
#21
JOURNAL ARTICLE
Lotte H J M Lemmens, Robert J DeRubeis, Tony Z Tang, Julia C C Schulte-Strathaus, Marcus J H Huibers
Background: The frequency and clinical impact of Sudden Gains -large symptom improvements during a single between-session interval-in psychotherapy for depression have been well established. However, there have been relatively few efforts to identify the processes that lead to sudden gains. Aim: To explore therapy processes associated with sudden gains in cognitive therapy for depression by examining changes in the sessions surrounding the gains, and the session preceding the gain in particular. Methods: Using ratings of video-recordings ( n = 36), we assessed the content, frequency and magnitude of within-session cognitive-, behavioral-, and interpersonal change, as well as the quality of the therapeutic alliance in the session prior to the gain (pre-gain session), the session after the gain (post-gain session) and a control session...
2021: Frontiers in Psychiatry
https://read.qxmd.com/read/33716864/commonly-reported-problems-and-coping-strategies-during-the-covid-19-crisis-a-survey-of-graduate-and-professional-students
#22
JOURNAL ARTICLE
Akash R Wasil, Rose E Franzen, Sarah Gillespie, Joshua S Steinberg, Tanvi Malhotra, Robert J DeRubeis
Background: The COVID-19 crisis has introduced a variety of stressors, while simultaneously decreasing the availability of strategies to cope with stress. In this context, it could be useful to understand issues that people find most concerning and ways in which they cope with stress. In this study, we explored these questions with a sample of graduate and professional students. Method: Using open-ended assessments, we asked participants ( n = 305) to identify their biggest challenge or concern ("top problem"), their most effective way of handling stress ("effective strategy"), and their most common way of handling stress ("common strategy")...
2021: Frontiers in Psychology
https://read.qxmd.com/read/33581481/the-relation-between-therapy-quality-therapy-processes-and-outcomes-and-identifying-for-whom-therapy-quality-matters-in-cbt-and-ipt-for-depression
#23
JOURNAL ARTICLE
Sanne J E Bruijniks, Robert J DeRubeis, Lotte H J M Lemmens, Frenk P M L Peeters, Pim Cuijpers, Marcus J H Huibers
BACKGROUND: Research on which therapy processes are crucial for whom is necessary to optimize treatment outcomes for major depressive disorder (MDD) but may be impeded by a lack of variation in therapy quality and because of individual differences in therapy response. The present study used a dataset with large variation in therapy quality to investigate the impact of therapy quality on change in therapy processes and outcome. Machine-learning techniques were used to explore individual differences in these relationships...
January 28, 2021: Behaviour Research and Therapy
https://read.qxmd.com/read/33534176/smartphone-apps-for-eating-disorders-a-systematic-review-of-evidence-based-content-and-application-of-user-adjusted-analyses
#24
JOURNAL ARTICLE
Akash R Wasil, Raveena Patel, Jin Young Cho, Rebecca M Shingleton, John R Weisz, Robert J DeRubeis
OBJECTIVE: To examine the frequency of evidence-based treatment elements in popular smartphone apps for eating disorders (EDs), and to characterize the extent to which real-world users encounter different elements. METHOD: We searched the Apple App Store and Google Play Store for apps offering treatment or support to individuals with EDs. Then, we created a codebook of 47 elements found in evidence-based treatments for EDs. We examined the presence or absence of each element within each ED app...
May 2021: International Journal of Eating Disorders
https://read.qxmd.com/read/33326891/adding-cognitive-therapy-to-antidepressant-medications-decreases-ssuicidal-ideation
#25
JOURNAL ARTICLE
Gabriela K Khazanov, Colin Xu, Steven D Hollon, Robert J DeRubeis, Michael E Thase
BACKGROUND: Psychotherapy for depression and antidepressant medications have both been associated with decreases in suicidal ideation. Studies have not examined whether adding psychotherapy to antidepressant medications further reduces suicidal ideation relative to medications alone in adults. METHODS: Participants (N = 452) were randomized to 7 months of treatment with antidepressant medications or combined treatment with both medications and cognitive therapy for depression...
December 8, 2020: Journal of Affective Disorders
https://read.qxmd.com/read/32964809/cross-trial-prediction-in-psychotherapy-external-validation-of-the-personalized-advantage-index-using-machine-learning-in-two-dutch-randomized-trials-comparing-cbt-versus-ipt-for-depression
#26
JOURNAL ARTICLE
Suzanne C Van Bronswijk, Sanne J E Bruijniks, Lorenzo Lorenzo-Luaces, Robert J Derubeis, Lotte H J M Lemmens, Frenk P M L Peeters, Marcus J H Huibers
Abstract Objective: Optimizing treatment selection may improve treatment outcomes in depression. A promising approach is the Personalized Advantage Index (PAI), which predicts the optimal treatment for a given individual. To determine the generalizability of the PAI, models needs to be externally validated, which has rarely been done. Method: PAI models were developed within each of two independent trials, with substantial between-study differences, that both compared CBT and IPT for depression (STEPd: n  = 151 and FreqMech: n  = 200)...
September 23, 2020: Psychotherapy Research: Journal of the Society for Psychotherapy Research
https://read.qxmd.com/read/32881542/reassessing-evidence-based-content-in-popular-smartphone-apps-for-depression-and-anxiety-developing-and-applying-user-adjusted-analyses
#27
JOURNAL ARTICLE
Akash R Wasil, Sarah Gillespie, Raveena Patel, Annemarie Petre, Katherine E Venturo-Conerly, Rebecca M Shingleton, John R Weisz, Robert J DeRubeis
OBJECTIVE: To assess the dissemination of evidence-based content within smartphone apps for depression and anxiety by developing and applying user-adjusted analysis -a method for weighting app content based on each app's number of active users. METHOD: We searched the Apple App Store and Google Play Store and identified 27 apps within the top search hits, which real-world users are most likely to encounter. We developed a codebook of evidence-based treatment elements by reviewing past research on empirically supported treatments...
November 2020: Journal of Consulting and Clinical Psychology
https://read.qxmd.com/read/32276239/outcomes-skill-acquisition-and-the-alliance-similarities-and-differences-between-clinical-trial-and-student-therapists
#28
JOURNAL ARTICLE
Lizabeth A Goldstein, Abby D Adler Mandel, Robert J DeRubeis, Daniel R Strunk
Considerable evidence from clinical trials supports the efficacy of cognitive therapy (CT) of depression. Less is known about outcomes when provided in other contexts, such as when provided by student therapists. We conducted a non-randomized comparison of student therapists vs. clinical trial therapists on change in depressive symptoms, dropout, change in CT skills, and therapeutic alliance among 100 clients with moderate to severe depression. Treatment manual and duration were the same. Clients treated by student therapists had largely comparable outcomes on depressive symptom change, therapeutic alliance, and CT skills...
March 24, 2020: Behaviour Research and Therapy
https://read.qxmd.com/read/32204742/treatment-selection-in-borderline-personality-disorder-between-dialectical-behavior-therapy-and-psychodynamic-psychiatric-management
#29
JOURNAL ARTICLE
John R Keefe, Thomas T Kim, Robert J DeRubeis, David L Streiner, Paul S Links, Shelley F McMain
BACKGROUND: No evidence-based therapy for borderline personality disorder (BPD) exhibits a clear superiority. However, BPD is highly heterogeneous, and different patients may specifically benefit from the interventions of a particular treatment. METHODS: From a randomized trial comparing a year of dialectical behavior therapy (DBT) to general psychiatric management (GPM) for BPD, long-term (2-year-post) outcome data and patient baseline variables (n = 156) were used to examine individual and combined patient-level moderators of differential treatment response...
August 2021: Psychological Medicine
https://read.qxmd.com/read/32146337/harnessing-single-session-interventions-to-improve-adolescent-mental-health-and-well-being-in-india-development-adaptation-and-pilot-testing-of-online-single-session-interventions-in-indian-secondary-schools
#30
JOURNAL ARTICLE
Akash R Wasil, Suh Jung Park, Sarah Gillespie, Rebecca Shingleton, Sachin Shinde, Sadhana Natu, John R Weisz, Steven D Hollon, Robert J DeRubeis
BACKGROUND: Many evidence-based prevention and intervention approaches for youth mental health exist, but most are time-consuming and expensive to deliver. Innovative approaches are needed to develop and disseminate scalable mental health interventions, especially for youth in low- and middle-income countries. Computerized single-session interventions (SSIs) may be able to overcome many of these implementation barriers, especially if deployed in school settings. METHODS: Guided by this logic, we designed three computerized SSIs (based on behavioral activation, gratitude, and growth mindset exercises) for delivery in Indian high schools...
February 26, 2020: Asian Journal of Psychiatry
https://read.qxmd.com/read/32122161/interpersonal-psychotherapy-versus-cognitive-therapy-for-depression-how-they-work-how-long-and-for-whom-key-findings-from-an-rct
#31
RANDOMIZED CONTROLLED TRIAL
Lotte H J M Lemmens, Suzanne C van Bronswijk, Frenk P M L Peeters, Arnoud Arntz, Anne Roefs, Steven D Hollon, Robert J DeRubeis, Marcus J H Huibers
OBJECTIVE: Although the effectiveness of interpersonal psychotherapy (IPT) and cognitive therapy (CT) for major depression has been established, little is known about how and for whom they work and how they compare in the long term. The latter is especially relevant for IPT because research on its long-term effects has been limited. This overview paper summarizes findings from a Dutch randomized controlled trial on the effects and mechanisms of change of IPT versus CT for major depression...
March 1, 2020: American Journal of Psychotherapy
https://read.qxmd.com/read/31896529/distress-and-anhedonia-as-predictors-of-depression-treatment-outcome-a-secondary-analysis-of-a-randomized-clinical-trial
#32
JOURNAL ARTICLE
Gabriela K Khazanov, Colin Xu, Barnaby D Dunn, Zachary D Cohen, Robert J DeRubeis, Steven D Hollon
Two core features of depression include depressed mood (heightened distress) and anhedonia (reduced pleasure). Despite their centrality to depression, studies have not examined their contribution to treatment outcomes in a randomized clinical trial providing mainstream treatments like antidepressant medications (ADM) and cognitive therapy (CT). We used baseline distress and anhedonia derived from a factor analysis of the Mood and Anxiety Symptom Questionnaire to predict remission and recovery in 433 individuals with recurrent/chronic major depressive disorder...
October 31, 2019: Behaviour Research and Therapy
https://read.qxmd.com/read/31815189/what-factors-indicate-prognosis-for-adults-with-depression-in-primary-care-a-protocol-for-meta-analyses-of-individual-patient-data-using-the-dep-gp-database
#33
JOURNAL ARTICLE
Joshua E J Buckman, Rob Saunders, Zachary D Cohen, Katherine Clarke, Gareth Ambler, Robert J DeRubeis, Simon Gilbody, Steven D Hollon, Tony Kendrick, Edward Watkins, Ian R White, Glyn Lewis, Stephen Pilling
Background : Pre-treatment severity is a key indicator of prognosis for those with depression. Knowledge is limited on how best to encompass severity of disorders. A number of non-severity related factors such as social support and life events are also indicators of prognosis. It is not clear whether this holds true after adjusting for pre-treatment severity as a) a depressive symptom scale score, and b) a broader construct encompassing symptom severity and related indicators: "disorder severity"...
2019: Wellcome Open Research
https://read.qxmd.com/read/31799993/prevention-of-recurrence-after-recovery-from-a-major-depressive-episode-with-antidepressant-medication-alone-or-in-combination-with-cognitive-behavioral-therapy-a-phase-2-randomized-clinical-trial
#34
JOURNAL ARTICLE
Robert J DeRubeis, John Zajecka, Richard C Shelton, Jay D Amsterdam, Jan Fawcett, Colin Xu, Paula R Young, Robert Gallop, Steven D Hollon
Importance: Antidepressant medication treatment is associated with the prevention of depressive recurrence in patients with major depressive disorder (MDD), but whether cognitive behavioral therapy (CBT) treatment is associated with recurrence prevention remains unclear. Objective: To determine the effects of combining CBT with antidepressant medications on the prevention of depressive recurrence when antidepressant medications are withdrawn or maintained after recovery in patients with MDD...
December 4, 2019: JAMA Psychiatry
https://read.qxmd.com/read/31753043/precision-medicine-for-long-term-depression-outcomes-using-the-personalized-advantage-index-approach-cognitive-therapy-or-interpersonal-psychotherapy
#35
JOURNAL ARTICLE
Suzanne C van Bronswijk, Robert J DeRubeis, Lotte H J M Lemmens, Frenk P M L Peeters, John R Keefe, Zachary D Cohen, Marcus J H Huibers
BACKGROUND: Psychotherapies for depression are equally effective on average, but individual responses vary widely. Outcomes can be improved by optimizing treatment selection using multivariate prediction models. A promising approach is the Personalized Advantage Index (PAI) that predicts the optimal treatment for a given individual and the magnitude of the advantage. The current study aimed to extend the PAI to long-term depression outcomes after acute-phase psychotherapy. METHODS: Data come from a randomized trial comparing cognitive therapy (CT, n = 76) and interpersonal psychotherapy (IPT, n = 75) for major depressive disorder (MDD)...
November 22, 2019: Psychological Medicine
https://read.qxmd.com/read/31706160/the-history-current-status-and-possible-future-of-precision-mental-health
#36
JOURNAL ARTICLE
Robert J DeRubeis
In evidence-based mental health practice, decisions must often be made for which there is little or no empirical basis. A common example of this is when there are multiple empirically supported interventions for a person with a given diagnosis, where the aim is to recommend the treatment most likely to be effective for that person. Data obtained from randomized clinical trials allow for the identification of patient characteristics that could be used to match patients to treatments. Historically, researchers have focused on individual moderators, single variables that interact statistically with treatment type, but these have rarely proved powerful enough to inform treatment decisions...
December 2019: Behaviour Research and Therapy
https://read.qxmd.com/read/31395363/predicting-optimal-interventions-for-clinical-depression-moderators-of-outcomes-in-a-positive-psychological-intervention-vs-cognitive-behavioral-therapy
#37
JOURNAL ARTICLE
Irene Lopez-Gomez, Lorenzo Lorenzo-Luaces, Covadonga Chaves, Gonzalo Hervas, Robert J DeRubeis, Carmelo Vazquez
Identifying differences in the clinical response to specific interventions is an important challenge in the field of Clinical Psychology. This is especially true in the treatment of depression where many treatments appear to have comparable outcomes. In a controlled trial, we compared a positive psychology group intervention, the Integrative Positive Psychological Intervention for Depression (IPPI-D; n = 62) to a cognitive-behavioral therapy group intervention (CBT; n = 66) for depression. No statistically or clinically-significant differences between the treatments were found, but a slight advantage was observed, on average, for IPPI-D...
July 9, 2019: General Hospital Psychiatry
https://read.qxmd.com/read/31059603/the-symptom-specific-efficacy-of-antidepressant-medication-vs-cognitive-behavioral-therapy-in-the-treatment-of-depression-results-from-an-individual-patient-data-meta-analysis
#38
JOURNAL ARTICLE
Lynn Boschloo, Ella Bekhuis, Erica S Weitz, Mirjam Reijnders, Robert J DeRubeis, Sona Dimidjian, David L Dunner, Boadie W Dunlop, Ulrich Hegerl, Steven D Hollon, Robin B Jarrett, Sidney H Kennedy, Jeanne Miranda, David C Mohr, Anne D Simons, Gordon Parker, Frank Petrak, Stephan Herpertz, Lena C Quilty, A John Rush, Zindel V Segal, Jeffrey R Vittengl, Robert A Schoevers, Pim Cuijpers
A recent individual patient data meta-analysis showed that antidepressant medication is slightly more efficacious than cognitive behavioral therapy (CBT) in reducing overall depression severity in patients with a DSM-defined depressive disorder. We used an update of that dataset, based on seventeen randomized clinical trials, to examine the comparative efficacy of antidepressant medication vs. CBT in more detail by focusing on individual depressive symptoms as assessed with the 17-item Hamilton Rating Scale for Depression...
June 2019: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
https://read.qxmd.com/read/30869969/in-session-emotional-expression-predicts-symptomatic-and-panic-specific-reflective-functioning-improvements-in-panic-focused-psychodynamic-psychotherapy
#39
JOURNAL ARTICLE
John R Keefe, Zeeshan M Huque, Robert J DeRubeis, Jacques P Barber, Barbara L Milrod, Dianne L Chambless
In panic-focused psychodynamic psychotherapy (PFPP), exploration and interpretation of avoided and conflicted emotions and fantasies surrounding anxiety are thought to promote panic-specific reflective functioning (PSRF), which drives panic disorder improvements. Patient emotional expression within a session may be a marker of engaged processing and experiencing of affectively charged material. Degree of in-session expressed emotion, indicating both verbal and nonverbal emotions, was examined across three early therapy sessions for prediction of subsequent outcomes...
March 14, 2019: Psychotherapy
https://read.qxmd.com/read/30867082/translating-the-bdi-and-bdi-ii-into-the-hamd-and-vice-versa-with-equipercentile-linking
#40
JOURNAL ARTICLE
Toshi A Furukawa, Mirjam Reijnders, Sanae Kishimoto, Masatsugu Sakata, Robert J DeRubeis, Sona Dimidjian, David J A Dozois, Ulrich Hegerl, Steven D Hollon, Robin B Jarrett, François Lespérance, Zindel V Segal, David C Mohr, Anne D Simons, Lena C Quilty, Charles F Reynolds, Claudio Gentili, Stefan Leucht, Rolf R Engel, Pim Cuijpers
AimsThe Hamilton Depression Rating Scale (HAMD) and the Beck Depression Inventory (BDI) are the most frequently used observer-rated and self-report scales of depression, respectively. It is important to know what a given total score or a change score from baseline on one scale means in relation to the other scale. METHODS: We obtained individual participant data from the randomised controlled trials of psychological and pharmacological treatments for major depressive disorders. We then identified corresponding scores of the HAMD and the BDI (369 patients from seven trials) or the BDI-II (683 patients from another seven trials) using the equipercentile linking method...
March 14, 2019: Epidemiology and Psychiatric Sciences
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