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https://www.readbyqxmd.com/read/28224732/pathways-into-psychopathology-modeling-the-effects-of-trait-emotional-intelligence-mindfulness-and-irrational-beliefs-in-a-clinical-sample
#1
K V Petrides, María G Gómez, Juan-Carlos Pérez-González
: We investigated possible pathways into mental illness via the combined effects of trait emotional intelligence (trait EI), mindfulness, and irrational beliefs. The sample comprised 121 psychiatric outpatients (64.5% males, mean age = 38.8 years) with a variety of formal clinical diagnoses. Psychopathology was operationalized by means of 3 distinct indicators from the Millon Clinical Multi-Axial Inventory (mild pathology, severe pathology, and clinical symptomatology). A structural equation model confirmed significant direct trait EI and mindfulness effects on irrational beliefs and psychopathology...
February 21, 2017: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/28214436/impact-of-child-maltreatment-on-meaning-in-life-in-psychiatric-patients
#2
Sébastien Weibel, Sonia Vidal, Emilie Olié, Roland Hasler, Catherine Torriani, Paco Prada, Philippe Courtet, Sébastien Guillaume, Nader Perroud, Philippe Huguelet
Child maltreatment (CM) worsens prognosis and quality of life in several psychiatric conditions. Meaning in life is a construct which relates to the sense of purpose that one can perceive in life, and is a key aspect of recovery in psychiatric patients. The lasting impact of CM on meaning in life and its mediating variables have not been studied in patients with chronic persistent psychiatric conditions. One hundred and sixty-six patients with bipolar disorder (N=35), psychotic disorder (N=73), anorexia nervosa (N=30) or borderline personality disorder (N=28) were assessed for meaning in life (revised version of the Life Regard Index (LRI-R)), for CM (Childhood Trauma Questionnaire (CTQ)) and for internalized/externalized psychopathology...
February 13, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28186637/perceived-burdensomeness-thwarted-belongingness-and-fearlessness-about-death-associations-with-suicidal-ideation-among-female-veterans-exposed-to-military-sexual-trauma
#3
Lindsey L Monteith, Nazanin H Bahraini, Deleene S Menefee
OBJECTIVE: Military sexual trauma (MST) is prevalent among female Veterans and is associated with increased risk for suicidal self-directed violence. Yet research examining processes which contribute to suicidal ideation and attempts among MST survivors has been sparse, focusing primarily on psychiatric symptoms or diagnoses, rather than employing a theory-driven approach. The interpersonal-psychological theory (Joiner, 2005) is a leading theory of suicide that may be particularly relevant for understanding suicidal ideation among female Veterans who have experienced MST...
February 10, 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28182138/construct-validity-of-the-depression-and-somatic-symptoms-scale-evaluation-by-mokken-scale-analysis
#4
Ya-Hsin Chou, Chin-Pang Lee, Chia-Yih Liu, Ching-I Hung
OBJECTIVE: Previous studies of the Depression and Somatic Symptoms Scale (DSSS), a free scale, have been based on the classical test theory, and the construct validity and dimensionality of the DSSS are as yet uncertain. The aim of this study was to use Mokken scale analysis (MSA) to assess the dimensionality of the DSSS. METHODS: A sample of 214 psychiatric outpatients with mood and anxiety disorders were enrolled at a medical center in Taiwan (age: mean [SD] =38...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28167616/towards-trans-diagnostic-mechanisms-in-psychiatry-neurobehavioral-profile-of-rats-with-a-loss-of-function-point-mutation-in-the-dopamine-transporter-gene
#5
Valentina Vengeliene, Anton Bespalov, Martin Roßmanith, Sandra Horschitz, Stefan Berger, Ana L Relo, Hamid R Noori, Peggy Schneider, Thomas Enkel, Dusan Bartsch, Miriam Schneider, Berthold Behl, Anita C Hansson, Patrick Schloss, Rainer Spanagel
The Research Domain Criteria (RDoC) matrix has been developed to reorient psychiatric research towards measurable behavioral dimensions and underlying mechanisms. Here we used a new genetic rat model with a loss of function point mutation in the dopamine transporter (DAT) gene (Slc6a3_N157K) to systematically study the RDoC matrix (www.nimh.nih.gov/research-priorities/rdoc/constructs/rdoc-matrix.shtml). First, we examined the impact of the Slc6a3_N157K mutation on monoaminergic signaling. We then performed behavioral tests representing each of the five RDoC domains - negative and positive valence systems, cognitive, social, and in arousal/regulatory systems...
February 6, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/28167349/proportional-thresholding-in-resting-state-fmri-functional-connectivity-networks-and-consequences-for-patient-control-connectome-studies-issues-and-recommendations
#6
Martijn van den Heuvel, Siemon de Lange, Andrew Zalesky, Caio Seguin, Thomas Yeo, Ruben Schmidt
Graph theoretical analysis has become an important tool in the examination of brain dysconnectivity in neurological and psychiatric brain disorders. A common analysis step in the construction of the functional graph or network involves "thresholding" of the connectivity matrix, selecting the set of edges that together form the graph on which network organization is evaluated. To avoid systematic differences in absolute number of edges, studies have argued against the use of an "absolute threshold" in case-control studies and have proposed the use of "proportional thresholding" instead, in which a pre-defined number of strongest connections are selected as network edges, ensuring equal network density across datasets...
February 3, 2017: NeuroImage
https://www.readbyqxmd.com/read/28163498/psychometric-properties-and-correlates-of-the-beck-hopelessness-scale-in-family-caregivers-of-nigerian-patients-with-psychiatric-disorders-in-southwestern-nigeria
#7
Olutayo Aloba, Olayinka Ajao, Taiwo Alimi, Olufemi Esan
OBJECTIVES: To examine the construct and correlates of hopelessness among family caregivers of Nigerian psychiatric patients. MATERIALS AND METHODS: This is a cross-sectional, descriptive study involving 264 family caregiver-patients' dyads recruited from two university teaching hospitals psychiatric clinics in Southwestern Nigeria. RESULTS: Exploratory factor analysis revealed a two-factor 9-item model of the Beck Hopelessness Scale (BHS) among the family caregivers...
December 2016: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28159590/pharmacogenetics-of-antidepressant-response-a-polygenic-approach
#8
Judit García-González, Katherine E Tansey, Joanna Hauser, Neven Henigsberg, Wolfgang Maier, Ole Mors, Anna Placentino, Marcella Rietschel, Daniel Souery, Tina Žagar, Piotr M Czerski, Borut Jerman, Henriette N Buttenschøn, Thomas G Schulze, Astrid Zobel, Anne Farmer, Katherine J Aitchison, Ian Craig, Peter McGuffin, Michel Giupponi, Nader Perroud, Guido Bondolfi, David Evans, Michael O'Donovan, Tim J Peters, Jens R Wendland, Glyn Lewis, Shitij Kapur, Roy Perlis, Volker Arolt, Katharina Domschke, Gerome Breen, Charles Curtis, Lee Sang-Hyuk, Carol Kan, Stephen Newhouse, Hamel Patel, Bernhard T Baune, Rudolf Uher, Cathryn M Lewis, Chiara Fabbri
BACKGROUND: Major depressive disorder (MDD) has a high personal and socio-economic burden and >60% of patients fail to achieve remission with the first antidepressant. The biological mechanisms behind antidepressant response are only partially known but genetic factors play a relevant role. A combined predictor across genetic variants may be useful to investigate this complex trait. METHODS: Polygenic risk scores (PRS) were used to estimate multi-allelic contribution to: 1) antidepressant efficacy; 2) its overlap with MDD and schizophrenia...
January 31, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28156468/assessment-tools-for-palliative-care
#9
Rebecca Aslakson, Sydney Morss Dy, Renee Wilson, Julie Waldfogel, Allen Zhang, Alex B Blair, Karen Robinson
: 66 Background: Recent reviews have not comprehensively addressed palliative care (PC) assessment tools. This project summarizes the extent of evidence about PC assessment tools for patients and families, and how tools have been used for clinical care, quality indicators, and evaluation of interventions. METHODS: We searched MEDLINE, CINAHL, and Cochrane Database of Systematic Reviews for systematic reviews of assessment tools for PC, from January 2007 to March 2016...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28154892/differential-effects-of-antipsychotic-and-propsychotic-drugs-on-prepulse-inhibition-and-locomotor-activity-in-roman-high-rha-and-low-avoidance-rla-rats
#10
Ignasi Oliveras, Ana Sánchez-González, Daniel Sampedro-Viana, Maria Antonietta Piludu, Cristóbal Río-Alamos, Osvaldo Giorgi, Maria G Corda, Susana Aznar, Javier González-Maeso, Cristina Gerbolés, Gloria Blázquez, Toni Cañete, Adolf Tobeña, Alberto Fernández-Teruel
RATIONALE: Animal models with predictive and construct validity are necessary for developing novel and efficient therapeutics for psychiatric disorders. OBJECTIVES: We have carried out a pharmacological characterization of the Roman high- (RHA-I) and low-avoidance (RLA-I) rat strains with different acutely administered propsychotic (DOI, MK-801) and antipsychotic drugs (haloperidol, clozapine), as well as apomorphine, on prepulse inhibition (PPI) of startle and locomotor activity (activity cages)...
February 2, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28154566/histological-architecture-underlying-brain-immune-cell-cell-interactions-and-the-cerebral-response-to-systemic-inflammation
#11
Atsuyoshi Shimada, Sanae Hasegawa-Ishii
Although the brain is now known to actively interact with the immune system under non-inflammatory conditions, the site of cell-cell interactions between brain parenchymal cells and immune cells has been an open question until recently. Studies by our and other groups have indicated that brain structures such as the leptomeninges, choroid plexus stroma and epithelium, attachments of choroid plexus, vascular endothelial cells, cells of the perivascular space, circumventricular organs, and astrocytic endfeet construct the histological architecture that provides a location for intercellular interactions between bone marrow-derived myeloid lineage cells and brain parenchymal cells under non-inflammatory conditions...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28150091/reliability-and-validity-of-the-short-version-of-udvalg-for-kliniske-undersogelser-in-antipsychotic-treatment
#12
Kun-Po Chen, For-Wey Lung
The aim of this study was to develop a reliable and valid short version of the Udvalg for Kliniske Undersogelser (UKU) to efficiently evaluate the side effects of antipsychotics in patients with schizophrenia. This multi-site study included 10 hospitals, which included 331 inpatients and outpatients diagnosed with schizophrenia. UKU, Clinical Global Impression-Severity (CGI-S), Personal and Social Performance (PSP) and dosage of paliperidone were collected. The predictive validity of the UKU-short version, as well as that of the CGI-S, PSP and paliperidone dosages, was analyzed using structural equation modeling (SEM), latent growth models (LGM), and confirmatory factor analysis to test its content and construct validity...
February 1, 2017: Psychiatric Quarterly
https://www.readbyqxmd.com/read/28146615/incorporation-of-mobile-application-app-measures-into-the-diagnosis-of-smartphone-addiction
#13
Yu-Hsuan Lin, Po-Hsien Lin, Chih-Lin Chiang, Yang-Han Lee, Cheryl C H Yang, Terry B J Kuo, Sheng-Hsuan Liln
OBJECTIVE: Global smartphone expansion has brought about unprecedented addictive behaviors. The current diagnosis of smartphone addiction is based solely on information from clinical interview. This study aimed to incorporate application (app)-recorded data into psychiatric criteria for the diagnosis of smartphone addiction and to examine the predictive ability of the app-recorded data for the diagnosis of smartphone addiction. METHODS: Smartphone use data of 79 college students were recorded by a newly developed app for 1 month between December 1, 2013, and May 31, 2014...
31, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28145043/objective-measures-of-sleep-duration-and-continuity-in-major-depressive-disorder-with-comorbid-hypersomnolence-a-primary-investigation-with-contiguous-systematic-review-and-meta-analysis
#14
REVIEW
David T Plante, Jesse D Cook, Michael R Goldstein
Hypersomnolence plays an important role in the presentation, treatment and course of mood disorders. However, there has been relatively little research that examines objective measures of sleep duration and continuity in patients with depression and hypersomnolence, despite the use of these factors in sleep medicine nosological systems. This study compared total sleep time and efficiency measured by naturalistic actigraphic recordings followed by ad libitum polysomnography (PSG; without prescribed wake time) in 22 patients with major depressive disorder and co-occurring hypersomnolence against age- and sex-matched healthy sleeper controls...
February 1, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28135997/exposure-to-suicidal-behaviors-a-common-suicide-risk-factor-or-a-personal-negative-life-event
#15
Keith M Harris, Silvana Bettiol
BACKGROUND: Numerous suicide risk factors have been proposed but not adequately validated for epidemiology, treatment and prevention efforts. AIMS: Exposures to suicidal behaviors (ESB), from family and friend suicide attempts and completions, were tested for validity as a suicidal risk factor and also for measurement and construct adequacy. METHODS: An anonymous online survey yielded 713 participants (aged 18-71), who reported ESB, completed the Suicidal Affect-Behavior-Cognition Scale (SABCS), and comprised a broad spectrum on those variables...
February 2017: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/28135757/-validation-of-the-german-translation-of-the-revised-trauma-symptom-inventory-tsi-2-to-assess-complex-posttraumatic-stress-symptoms
#16
Sandy Krammer, Heidi Grossenbacher, Nathalie Goldstein, Carole Kaufmann, Alesia Schwenzel, Michael Soyka
The study aimed to validate the German version of the revised Trauma Symptom Inventory (TSI-2) by John Briere. TSI-2 assesses complex posttraumatic stress symptoms. In order to validate it, further instruments were applied, namely the Adverse Childhood Experience Scale, the CIDI list, the revised Impact of Event-Scale, the interview for complex posttraumatic stress disorder, the revised symptom checklist 90, the dissociative experiences scale, the inventory for interpersonal problems, and the self-efficacy questionnaire...
January 30, 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/28120251/shyness-trajectories-across-the-first-four-decades-predict-mental-health-outcomes
#17
Alva Tang, Ryan J Van Lieshout, Ayelet Lahat, Eric Duku, Michael H Boyle, Saroj Saigal, Louis A Schmidt
Although childhood shyness is presumed to predict mental health problems in adulthood, no prospective studies have examined these outcomes beyond emerging adulthood. As well, existing studies have been limited by retrospective and cross-sectional designs and/or have examined shyness as a dichotomous construct. The present prospective longitudinal study (N = 160; 55 males, 105 females) examined shyness trajectories from childhood to the fourth decade of life and mental health outcomes. Shyness was assessed using parent- and self-rated measures from childhood to adulthood, once every decade at ages 8, 12-16, 22-26, and 30-35...
January 25, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28118266/one-hundred-years-of-psychiatry-at-johns-hopkins-a-story-of-meyer-to-mchugh
#18
J Raymond DePaulo
This article describes a history of clinical methods and constructs that guide Psychiatry at Johns Hopkins Phipps Clinic today. The contributions of Adolf Meyer and Paul McHugh are central and closely connected. Both emphasize the clinical examination as the central practice of psychiatry as a specialty within medicine. Meyer's comprehensive examination of the patient became the centerpiece of his approach and was the standard for psychiatrists in the English-speaking world. McHugh, with Phillip Slavney, developed a pluralistic and practical framework for interpreting that history and examination...
January 23, 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/28112810/perceived-criticism-in-the-treatment-of-a-high-risk-adolescent
#19
Jill M Hooley, David J Miklowitz
Perceived criticism (PC) is a construct that plays a key role in family relationships of persons with psychiatric disorders. It can be assessed in a brief and simple way using the Perceived Criticism Measure. PC ratings made by patients about their caregivers predict adverse clinical outcomes including increases in symptoms and relapse across a broad range of psychiatric diagnoses. Although research supports the concurrent and predictive validity of PC, the measure is not widely used in clinical practice. Here, we describe the construct of PC and review evidence supporting its clinical utility...
January 23, 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28110111/applying-a-novel-statistical-method-to-advance-the-personalized-treatment-of-anxiety-disorders-a-composite-moderator-of-comparative-drop-out-from-cbt-and-act
#20
Andrea N Niles, Kate B Wolitzky-Taylor, Joanna J Arch, Michelle G Craske
BACKGROUND: No prior studies have examined moderators of dropout between distinct treatments for anxiety disorders. This study applied a novel statistical approach for examining moderators of dropout from traditional cognitive behavioral therapy (CBT) and acceptance and commitment therapy (ACT). METHOD: We combined data from two randomized controlled trials (N = 208) comparing CBT and ACT for patients with DSM-IV anxiety disorders. Adapting Kraemer's method for constructing and evaluating composite moderators (2013), 26 variables were examined for individual effect sizes...
January 4, 2017: Behaviour Research and Therapy
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