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Canser Yilmaz Demir
BACKGROUND The aim of this study was to investigate the effects of various ratios of hemodilution on the survival of McFarlane's skin flaps. MATERIAL AND METHODS An experimental study was performed on 42 adult male Wistar rats (weighing 260 to 305 g) allocated to a control group without any volume loss and to 6 study groups with hemodilution ratios of 5%, 10%, 15%, 20%, 25%, and 30%. In all subjects, random-pattern McFarlane's skin flaps were uniformly elevated and re-sutured to the donor sites. The amount of necrosis was evaluated on the 7th day postoperatively and compared among the groups...
March 9, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Canser Yilmaz Demir, Nureddin Yuzkat
BACKGROUND: Emergence agitation (EA), defined as restlessness, disorientation, excitation, and/or inconsolable crying, is a common phenomenon during early recovery from general anesthesia. In this study, we aimed to determine the (1) EA incidence after rhinoplasty operations in adults; (2) the effects of ketamine administered at sub-anesthetic doses just 20 min before the end of the surgery in rhinoplasty operations on agitation level, postoperative pain, side effects, and complications; and (3) to determine the risk factors for EA in adults after rhinoplasty...
February 20, 2018: Aesthetic Plastic Surgery
Canser Yilmaz Demir, Muhammet Eren Ersoz, Remzi Erten, Omer Faruk Kocak, Yilmaz Sultanoglu, Yildiray Basbugan
BACKGROUND: The purpose of this study was to compare the effects of oral enalapril, an angiotensin-converting enzyme inhibitor (ACE-I), oral candesartan, an angiotensin receptor blocker (ARB), and intralesional corticosteroid treatments in reducing scar formation. METHODS: Twenty male rabbits were divided into five study groups: A (sham), B (control), C (ACE-I), D (ARB) and E (intralesional corticosteroid). The rabbit ear hypertrophic scar model was used. The hypertrophic scars were photographed and analyzed with the program ImageJ quantitatively to determine the degree of collagen fibers...
April 2018: Aesthetic Plastic Surgery
Canser Yilmaz Demir, Omer Faruk Kocak, Nazim Bozan, Muhammet Eren Ersoz, Halit Demir
PURPOSE: Data on the role of oxidative stress in temporomandibular joint (TMJ) disorders are limited. This study compared serum levels of oxidative stress indicators and antioxidant enzymes in patients with TMJ disorders. PATIENTS AND METHODS: In this prospective study, patients with TMJ disorders and healthy controls were compared for descriptive characteristics (age and gender) and serum levels of malondialdehyde (MDA), an oxidative stress marker, and antioxidant enzymes catalase (CAT), glutathione (GSH), and superoxide dismutase (SOD)...
March 2018: Journal of Oral and Maxillofacial Surgery
Nazim Bozan, Ömer Faruk Kocak, Mehmet Emre Dinc, Canser Yilmaz Demir, Mahfuz Turan, Ahmet Faruk Kiroglu
OBJECTIVE: Carotid body tumors (CBTs) are rare hypervascular benign tumors that originate from the paraganglia at the carotid bifurcation. The red cell distribution width (RDW), neutrophil-to-lymphocyte ratio (NLR), and mean platelet volume (MPV) may serve as markers in inflammatory, cardiovascular, and neoplastic diseases. However, their prognostic value in CBTs is unknown. The purpose of this study was to assess the leukocyte count, MPV, RDW, and NLR before and after surgery in patients with CBTs...
October 2017: Journal of Craniofacial Surgery
Canser Yilmaz Demir, Yılmaz Sultanoglu, Omer Faruk Kocak, Muhammet Eren Ersoz
OBJECTIVE: To compare the perioperative findings of inferior pedicle reduction mammoplasty (IPRM) performed with or without a tourniquet. METHODS: This study was carried out in the plastic and reconstructive surgery department at a tertiary care center on a total of 42 consecutive women scheduled for IPRM. Patients in Group I (n = 21) underwent surgery using a tourniquet, whereas patients in Group II (n = 21) were operated on without a tourniquet. Levels of hemoglobin (Hb), hematocrit (Hct), Hct/Hb ratio, and platelet counts were noted preoperatively and on postoperative 24th and 48th h...
October 2017: Aesthetic Plastic Surgery
Omer Faruk Kocak, Canser Yilmaz Demir
BACKGROUND: Dorsal intercostal artery perforator (DICAP) flap is an ideal flap to be used for posterior trunk defects since it leads to lower donor-site morbidity and shorter operative times, offers easy surgical planning, and uses a reliable and easily identifiable artery. MATERIALS AND METHODS: The study retrospectively reviewed 52 patients with meningomyelocele defects that were closed with DICAP flap between January 2007 and May 2015. SURGICAL TECHNIQUE: Each of the 4th to 12th posterior intercostal arteries can be used as dorsal perforators...
November 2016: Journal of Craniofacial Surgery
Omer Faruk Kocak, Canser Yilmaz Demir
BACKGROUND: Dorsal intercostal artery perforator (DICAP) flap is an ideal flap to be used for posterior trunk defects since it leads to lower donor-site morbidity and shorter operative times, offers easy surgical planning, and uses a reliable and easily identifiable artery. MATERIALS AND METHODS: The study retrospectively reviewed 52 patients with meningomyelocele defects that were closed with DICAP flap between January 2007 and May 2015. SURGICAL TECHNIQUE: Each of the 4th to 12th posterior intercostal arteries can be used as dorsal perforators...
August 24, 2016: Journal of Craniofacial Surgery
Kerem Taken, Mehmet Resit Oncu, Muslum Ergun, Recep Eryilmaz, Canser Yilmaz Demir, Murat Demir, Mustafa Gunes
OBJECTIVE: To report our experience with Fournier's Gangrene (FG) over the past eight years and evaluate the predisposing factors which affect the mortality. METHODS: Sixty-five patients who were admitted to emergency surgical unit of our institution presenting with FG between January 2006 and August 2014 were included. The anatomical site of infective gangrene, predisposing factors, etiological factors, and outcomes were retrospectively reviewed. RESULTS: Our cases included 8 women and 57 men...
May 2016: Pakistan Journal of Medical Sciences Quarterly
Omer Faruk Kocak, Nazim Bozan, Mustafa Oksuz, Serdar Yuce, Canser Yılmaz Demir, Gulay Bulut, Murat Cetin Ragbetli
Thymoquinone (TQ) is a plant extract that has been shown to have antioxidant, anti-inflammatory, angiogenic, antimicrobial, and anticarcinogenic effects. The aim of this study is to research how the use of TQ affects flap viability. 42 rats were placed into 6 groups, with 7 rats in each. A 3 × 10 cm McFarlane flap model was used on the test animals. The sham group had used neither surgical nor TQ treatment. The control group had surgery but no treatment afterwards. The preoperative TQ group was given oral doses of 2 mg/kg...
August 2016: Journal of Membrane Biology
Ş Güniz Küçükgüzel, Göknil P Coşkun
Cancer is known as abnormal cell division and consisting of a group of diseases on various organ tissues. Many therapies are available in cancer treatment such as chemotherapy, radiotherapy etc. Without damaging normal tissue, there is a huge need for specified anticancer drugs which have effect only on abnormal cancer cells. Therefore, advances in anticancer drug discovery in treating cancer in the recent years, directed towards to the macromolecular targets. Heterocyclic molecules, such as fluconazole, acetazolamide, etc...
2016: Anti-cancer Agents in Medicinal Chemistry
Atay Uludokumaci, Sule Canberk, Bilge Baskir Elcin, Nesrin Uygun, Canser Cakalir, Mehmet Canberk
No abstract text is available yet for this article.
2014: CytoJournal
P M De-Rufino Rivas, O Antolín Guerra, I Casuso Ruiz, C Mico Diaz, T Amigo Lanza, M J Noriega Borge, A Santamaría Pablos, S Sobaler Castañeda, P Jaen Canser, M Carrasco Martinez, R Salcines Medrano, L A Rivero Benito, C Redondo Figuero
OBJECTIVE: To analyse nutritional risk, by age and sex, among primary and secondary education adolescents from Cantabria. METHODOLOGY: a cross-sectional study was carried out, analysing a sample of 1101 adolescents: 568 (51.6%) were men and 533 (48.4%) were women, aged 12 to 17, attending 16 different primary and secondary education centres in Cantabria, by means of a Krece Plus questionnaire. RESULTS: A high percentage of adolescents with a high nutritional risk (35%) can be observed...
2014: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Enrique Canser, Blanca Martínez-Serrano, Azahara Sancho, Alberto Alonso-Babarro, Yolanda Vilches, Eduardo Alonso-Yanci, Elena Gredilla, Fernando Gilsanz
UNLABELLED: To achieve a successful pain control, interventional techniques are required in approximately 15% of the patients admitted to the Palliative Care Service (PCS). OBJECTIVES: To evaluate the frequency and effectiveness of the invasive procedures performed in the PCS of our health area. Other matters studied included complications associated with these procedures, the effects on morphine consumption, and functional status, survival rate, as well as the type and location of pain...
September 2014: Pain Practice: the Official Journal of World Institute of Pain
M Iu Kabanov, A A Gaĭdash, N V Rukhliada, I A Solov'ev, R V Titov, A P Utochkin, S I Smirnov, N V Smolin, M V Tiurin
The article is devoted to the aspects of a current state of surgical service in the Navy, prospects of development of professianl training for navy surgeons, formation of modern training comlex, united electronic library, containig the issues about combat surgical trauma, software technologies, realizing of the application methodology during the process of training and practical activity for the development of the training system for surgeons of Navy and improvement of effectiveness. Formation of normative technical documents, regulating activity of navy surgians is also among the expectations...
June 2013: Voenno-medit︠s︡inskiĭ Zhurnal
Sule Canberk, Atay Uludokumaci, Ceyda Sonmez, Canser Cakalir, Fatih Gulsen, Gulsen Ozbay
BACKGROUND: Hepatocellular carcinoma (HCC) accounts for approximately 80% of all the primary malignant tumors of the liver. Hepatoblastoma (HBL) is the most common primary malignant neoplasm of the liver in childhood, and extremely rare in adults. To the best of our knowledge, this is the first report of an adult case with cytopathologic description of a combined HCC and HBL, occurring in a noncirrhotic liver. CASE: A 24-year-old male was admitted to the hospital with right-sided abdominal pain...
2013: Acta Cytologica
Blanca Martínez, Enrique Canser, Elena Gredilla, Eduardo Alonso, Fernando Gilsanz
The literature contains numerous studies on the diagnosis, pathogenesis, atypical locations, and clinical (hormonal) and surgical management of the disorder. However, no information is available on the management of endometriosis involving pain refractory to the usual treatment from the perspective of a pain unit. Our hospital has a pain unit specifically dedicated to pain in gynecology and obstetrics. The unit has been functioning since December 2005, and 52% of the attended patients have CPP of different origins...
January 2013: Pain Practice: the Official Journal of World Institute of Pain
Pen-Yuan Chu, Yen-Bin Hsu, Tsung-Lun Lee, Sherry Fu, Li-Mei Wang, Ya-Chung Kao
BACKGROUND: We proposed a modified type III cordectomy for the treatment of early glottic cancer that removed the upper part of the vocalis muscle to improve glottic closure and voice outcomes. METHODS: Twenty-two patients with early glottic cancer underwent type III cordectomy, including 9 classical (proposed by European Laryngological Society) and 13 modified resections. Multidimensional voice evaluations were performed. RESULTS: Voice parameters including GRBAS (overall grade [G], roughness of the voice [R], breathiness [B], asthenicity [A], and strain [S]), jitter, shimmer, noise-to-harmonic ratio, maximum phonation time, voice handicap index-functional, physical, and total scores were better in modified resection...
October 2012: Head & Neck
Tülin Öztürk, Özlem Timirci Kahraman, Bahar Toptaş, Halil İbrahim Kisakesen, Canser Çakalir, Levent Verim, Oğuz Öztürk, Turgay İsbir
BACKGROUND: The aim of this study was to investigate a possible association of the CYP1A1 Ile462Val and GSTM1 null polymorphisms with the risk of developing bladder cancer in a Turkish population. PATIENTS AND METHODS: The study constituted 176 patients with bladder cancer and 97 healthy individuals. Evaluation of CYP1A1 Ile462Val gene polymorphism was performed by polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP). GSTM1 null gene polymorphism was exclusively determined by PCR...
July 2011: In Vivo
E Alonso Yanci, F Gilsanz Rodríguez, E Gredilla Díaz, B Martínez Serrano, E Canser Cuenca
Despite the theoretical advantages of continuous anesthesia in obstetric patients (good-quality blockade at low doses, good hemodynamic stability, rapid onset of effect, and no risk of toxicity), little has been published on this technique and its use in pregnancy. Moreover, few descriptive studies or comparative trials have evaluated the efficacy and safety of continuous spinal anesthesia, probably because of concerns about potential adverse effects-principally neurologic complications and postdural puncture headache...
March 2011: Revista Española de Anestesiología y Reanimación
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