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https://www.readbyqxmd.com/read/29777801/computer-simulation-of-neutral-drift-among-limbal-epithelial-stem-cells-of-mosaic-mice
#1
John D West, Richard L Mort, Robert E Hill, Steven D Morley, J Martin Collinson
The use of mice that are mosaic for reporter gene expression underlies many lineage-tracing studies in stem cell biology. For example, using mosaic LacZ reporter mice, it was shown that limbal epithelial stem cells (LESCs) around the periphery of the cornea maintain radial sectors of the corneal epithelium and that radial stripe numbers declined with age. Originally, the corneal results were interpreted as progressive, age-related loss or irreversible inactivation of some LESC clones. In this study we used computer simulations to show that these results could also be explained by stochastic replacement of LESCs by neighbouring LESCs, leading to neutral drift of LESC populations...
May 13, 2018: Stem Cell Research
https://www.readbyqxmd.com/read/29777778/anterior-approach-in-humeral-plating-osteosynthesis
#2
Daniel Handy Eone, Prudence Christelle Danielle Ngono, Marie Josée Essi, Gaël Leckpa, Kennedy Olivier Muluem, Farikou Ibrahima, Maurice Aurélien Sosso
CONTEXT: Humeral plating osteosynthesis is controversial, particularly regarding the choice between anterior and lateral approach, data for which in the context of a low-income country are lacking. HYPOTHESIS: The anterior approach is an easy surgical technique, allowing good anatomic reconstruction. We hypothesize that the anterior approach is associated with fewer neurovascular lesions and functional sequelae than the lateral approach. MATERIALS AND METHODS: A retrospective study with assessment update was carried out over a period of 6 years 4 months from January 2010 to June 2016, with consecutive recruitment in the city of Yaoundé, Cameroon...
May 16, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29777260/flexor-carpi-radialis-brevis-case-report-of-a-symptomatic-tear
#3
Anthony M Kordahi, Kara L Sarrel, Sameer B Shah, Eric Y Chang
Anatomical variants of muscle are commonly encountered by surgeons and radiologists. The flexor carpi radialis brevis (FCRB) is an anomalous muscle in the distal forearm with an estimated prevalence of 2-8%. In the literature, there are a few case reports of symptomatic FCRB tenosynovitis without a concomitant tear, and treatment methods described include both conservative and surgical management. We present a case of one patient with radial sided wrist pain and a partial FCRB tear, which to our knowledge is the first case report of a symptomatic FCRB tear...
May 18, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29777180/radial-artery-versus-saphenous-vein-grafts
#4
Alexandra Le Bras
No abstract text is available yet for this article.
May 17, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29777035/septin-dependent-remodeling-of-cortical-microtubule-drives-cell-reshaping-during-epithelial-wound-healing
#5
Asako Shindo, Anastasia Audrey, Maki Takagishi, Masahide Takahashi, John B Wallingford, Makoto Kinoshita
Wounds in embryos heal rapidly through the contraction of the wound edges. Despite well-recognized significance of the actomyosin purse-string for wound closure, roles for other cytoskeletal components are largely unknown. Here, we report that the septin cytoskeleton cooperates with actomyosin and microtubules to coordinate circumferential contraction of the wound margin and concentric elongation of wound-proximal cells in Xenopus laevis embryos. Microtubules reoriented radially, forming bundles along lateral cell cortices in elongating wound-proximal cells...
May 18, 2018: Journal of Cell Science
https://www.readbyqxmd.com/read/29776470/clinical-outcomes-of-anconeus-interposition-arthroplasty-after-radial-head-resection-in-native-and-prosthetic-radial-heads
#6
Hithem Rahmi, Julie A Neumann, Christopher Klein, Carola F van Eck, Brian K Lee, John Itamura
BACKGROUND: Radiocapitellar pathology after traumatic injury to the elbow can be challenging to treat. The anconeus interposition arthroplasty has been proposed to treat radiocapitellar or proximal radioulnar joint dysfunction and pain, or both. This study evaluated whether radial head excision (native or prosthetic), followed by an anconeus interposition arthroplasty, relieves pain and improves subjective and objective elbow function in patients with post-traumatic radiocapitellar pathology...
June 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29776180/sensitivity-of-electrospray-molecular-dynamics-simulations-to-long-range-coulomb-interaction-models
#7
Neil A Mehta, Deborah A Levin
Molecular dynamics (MD) electrospray simulations of 1-ethyl-3-methylimidazolium tetrafluoroborate (EMIM-BF_{4}) ion liquid were performed with the goal of evaluating the influence of long-range Coulomb models on ion emission characteristics. The direct Coulomb (DC), shifted force Coulomb sum (SFCS), and particle-particle particle-mesh (PPPM) long-range Coulomb models were considered in this work. The DC method with a sufficiently large cutoff radius was found to be the most accurate approach for modeling electrosprays, but, it is computationally expensive...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29776152/analytical-method-for-analysis-of-electromagnetic-scattering-from-inhomogeneous-spherical-structures-using-duality-principles
#8
M Kiani, A Abdolali, M Safari
In this article, an analytical approach is presented for the analysis of electromagnetic (EM) scattering from radially inhomogeneous spherical structures (RISSs) based on the duality principle. According to the spherical symmetry, similar angular dependencies in all the regions are considered using spherical harmonics. To extract the radial dependency, the system of differential equations of wave propagation toward the inhomogeneity direction is equated with the dual planar ones. A general duality between electromagnetic fields and parameters and scattering parameters of the two structures is introduced...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29776046/radial-restricted-solid-on-solid-and-etching-interface-growth-models
#9
Sidiney G Alves
An approach to generate radial interfaces is presented. A radial network recursively obtained is used to implement discrete model rules designed originally for the investigation in flat substrates. I used the restricted solid-on-solid and etching models as to test the proposed scheme. The results indicate the Kardar, Parisi, and Zhang conjecture is completely verified leading to a good agreement between the interface radius fluctuation distribution and the Gaussian unitary ensemble. The evolution of the radius agrees well with the generalized conjecture, and the two-point correlation function exhibits also a good agreement with the covariance of the Airy_{2} process...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29775983/classification-and-microvascular-flap-selection-for-anterior-cranial-fossa-reconstruction
#10
James D Vargo, Wojciech Przylecki, Paul J Camarata, Brian T Andrews
BACKGROUND:  Microvascular reconstruction of the anterior cranial fossa (ACF) creates difficult challenges. Reconstructive goals and flap selection vary based on the defect location within the ACF. This study evaluates the feasibility and reliability of free tissue transfer for salvage reconstruction of low, middle, and high ACF defects. METHODS:  A retrospective review was performed. Reconstructions were anatomically classified as low (anterior skull base), middle (frontal bar/sinus), and high (frontal bone/soft tissue)...
May 18, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29774952/plant-roots-redesign-the-rhizosphere-to-alter-the-three-dimensional-physical-architecture-and-water-dynamics
#11
Sheikh M F Rabbi, Matthew K Tighe, Richard J Flavel, Brent N Kaiser, Chris N Guppy, Xiaoxian Zhang, Iain M Young
The mechanisms controlling the genesis of rhizosheaths are not well understood, despite their importance in controlling the flux of nutrients and water from soil to root. Here, we examine the development of rhizosheaths from drought-tolerant and drought-sensitive chickpea varieties; focusing on the three-dimensional characterization of the pore volume (> 16 μm voxel spatial resolution) obtained from X-ray microtomography, along with the characterization of mucilage and root hairs, and water sorption. We observe that drought-tolerant plants generate a larger diameter root, and a greater and more porous mass of rhizosheath, which also has a significantly increased water sorptivity, as compared with bulk soil...
May 18, 2018: New Phytologist
https://www.readbyqxmd.com/read/29774884/-application-of-radial-arterial-puncture-cannulation-under-ultrasonic-guidance-in-patients-with-critical-diseases
#12
Lan Cao, Lina Zhang, Meilin Ai, Li Li, Dun Tian, Yang Sun, Luxi Deng
To explore the clinicaleffect of radial arterial puncture cannulationunder ultrasonic guidance in patients with critical diseases.
 Methods: From December 2016 to May 2017, 120 patients under critical conditions in Department ofIntensive Care Unit, Xiangya Hospital, Central South University, who received arterial cannulation, were randomly divided into 2 groups: a control group (traditional blind puncture method) and an observation group (ultrasound-guided radial arterial cannulation) (60 cases in each group)...
April 28, 2018: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/29773973/comprehensive-investigation-of-white-matter-tracts-in-professional-chess-players-and-relation-to-expertise-region-of-interest-and-dmri-connectometry
#13
Mahsa Mayeli, Farzaneh Rahmani, Mohammad Hadi Aarabi
Purpose: Expertise is the product of training. Few studies have used functional connectivity or conventional diffusometric methods to identify neural underpinnings of chess expertise. Diffusometric variables of white matter might reflect these adaptive changes, along with changes in structural connectivity, which is a sensitive measure of microstructural changes. Method: Diffusometric variables of 29 professional chess players and 29 age-sex matched controls were extracted for white matter regions based on John Hopkin's Mori white matter atlas and partially correlated against professional training time and level of chess proficiency...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29773754/a-critical-neurodevelopmental-role-for-l-type-voltage-gated-calcium-channels-in-neurite-extension-and-radial-migration
#14
Satoshi Kamijo, Yuichiro Ishii, Shin-Ichiro Horigane, Kanzo Suzuki, Masamichi Ohkura, Junichi Nakai, Hajime Fujii, Sayaka Takemoto-Kimura, Haruhiko Bito
In spite of many association studies linking gene polymorphisms and mutations of L-type Voltage-Gated Ca2+ Channels (VGCC) in neurodevelopmental disorders, such as autism and schizophrenia, specific L-type VGCC roles during brain development remain unclear. Yet, calcium signaling has been shown to be essential for neurodevelopmental processes such as sculpting of neurites, functional wiring and fine tuning of growing networks. To bridge this gap, we performed submembraneous calcium imaging using a membrane-tethered genetically-encoded calcium indicator (GECI) Lck-G-CaMP7...
May 17, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29773240/perioperative-risk-factors-that-predict-complications-of-radial-forearm-free-flaps-in-oral-and-maxillofacial-reconstruction
#15
C Wang, G Fu, F Liu, L Liu, M Cao
The aim of the study was to find out what perioperative risk factors predicted complications in patients having reconstructions with radial forearm free flaps (RFFF). We organised a retrospective study of 169 patients (mean (range) age 54 (22-86) years, 100 of whom were female) who had oral and maxillofacial tumours resected, and reconstructed with RFFF, from January 2011-December 2016. We recorded predictive variables, subdivided into: personal and clinical (sex, age, weight, coexisting conditions, history of smoking, radiotherapy, and primary lesions); haemodynamic (perioperative concentrations of haemoglobin and albumin, blood loss, blood transfusion, urinary output (ml), and rate (ml/kg/hour), and infusion rates for crystalloids and colloids (ml/kg/hour, and volumes given intraoperatively and postoperatively for 24hours); and anaesthetic and surgical (American Society of Anesthesiologists(ASA) grade, visual analogue pain score (VAS), and duration of tourniquet and operation)...
May 14, 2018: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29772874/spatial-electromagnetic-field-intensity-modelling-of-global-system-for-mobile-communication-base-stations-in-the-istanbul-technical-university-ayazaga-campus-area
#16
Kubra Boz, Hayri Hakan Denli
The rapid development of the global system for mobile communication services and the consequent increased electromagnetic field (EMF) exposure to the human body have generated debate on the potential danger with respect to human health. The many research studies focused on this subject have, however, not provided any certain evidence about harmful consequences due to mobile communication systems. On the other hand, there are still views suggesting such exposure might affect the human body in different ways...
May 7, 2018: Geospatial Health
https://www.readbyqxmd.com/read/29771934/multilevel-analysis-of-dendroclimatic-series-with-the-r-package-biodry
#17
Wilson Lara, Stella Bogino, Felipe Bravo
The R-package BIOdry allows to model and compare fluctuations of Tree-ring Width (TRW) and climate, or dendroclimatic fluctuations, while accounting for source variability. The package eases multilevel modeling and multivariate comparison in dendroclimatic analysis using the nlme and ecodist packages, respectively. For implementing such libraries, the in-package algorithms transform the dendroclimatic fluctuations into Multilevel Dendroclimatic Data Series and maintain categorical variables and time units in the outputs...
2018: PloS One
https://www.readbyqxmd.com/read/29771857/erratum-to-what-injury-mechanism-and-patterns-of-ligament-status-are-associated-with-isolated-coronoid-isolated-radial-head-and-combined-fractures
#18
Ji-Ho Lee
No abstract text is available yet for this article.
June 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29771398/a-cadaveric-study-of-the-mean-distance-of-the-radial-artery-during-the-approach-to-the-first-carpometacarpal-joint
#19
Baris Yildirim, Daniel E Hess, Jesse B Seamon, Matthew L Lyons, A Rashard Dacus
Multiple surgical procedures have been described to treat first carpometacarpal (CMC) arthritis. Although the superiority of one procedure over the others continues to be a controversial topic, they all approach the trapezium and require careful attention to the surrounding structures. One potential complication is injury to the radial artery, which lies in close proximity to the trapezium and is often encountered during surgical approach. Using cadaveric specimens, the authors dissected to identify and isolate the radial artery as it travels in the forearm, wrist, and hand while being careful not to disturb its native course...
May 16, 2018: Orthopedics
https://www.readbyqxmd.com/read/29771366/linking-stem-growth-respiration-to-the-seasonal-course-of-stem-growth-and-gpp-of-scots-pine
#20
Tommy Chan, Frank Berninger, Pasi Kolari, Eero Nikinmaa, Teemu Hölttä
Current methods to study relations between stem respiration and stem growth have been hampered by problems in quantifying stem growth from dendrometer measurements, particularly on a daily time scale. This is mainly due to the water-related influences within these measurements that mask growth. A previously published model was used to remove water-related influences from measured radial stem variations to reveal a daily radial growth signal (ΔˆGm). We analysed the intra- and inter-annual relations between ΔˆGm and estimated growth respiration rates (Rg) on a daily scale for 5 years...
May 16, 2018: Tree Physiology
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