keyword
MENU ▼
Read by QxMD icon Read
search

packing hepatic

keyword
https://www.readbyqxmd.com/read/29345438/evaluation-of-hepatic-glycogen-content-some-haematological-and-biochemical-parameters-of-alloxan-induced-diabetic-rats-treated-with-combinations-of-glibenclamide-and-g-latifolium-extract
#1
Patrick E Aba
Background Diabetes is associated with both biochemical and haematological complications. Combination therapy has been advocated to mitigate some of these complications. Aim This study was designed to investigate the effects of glibenclamide and Gongronema latifolium (GL) on hepatic glycogen content and haemato-biochemical parameters. Methods Thirty male Wistar rats were assigned into five groups of six rats each. Groups 2-5 rats received intraperitoneally, 160 mg/kg of alloxan monohydrate while group 1 rats served as normal control...
May 4, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/29316006/extubation-in-the-operating-room-after-pediatric-liver-transplant-a-retrospective-cohort-study
#2
Harshad G Gurnaney, Scott D Cook-Sather, Abraham Shaked, Kim M Olthoff, Elizabeth B Rand, Arul M Lingappan, Mohamed A Rehman
BACKGROUND: Early extubation immediately following liver transplantation is increasingly common in adult practice. Some pediatric institutions have begun to adopt this strategy. Careful patient selection is essential in minimizing risk. METHODS: This retrospective cohort study evaluated infants and children who underwent liver transplantation between July 2011 and December 2014. Our primary objective was to determine early extubation rate. Secondary objectives were to identify clinical factors associated with successful early extubation compared with delayed extubation and to examine significant postoperative complications, intensive care unit length of stay, and hospital length of stay...
January 8, 2018: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/29310928/sofosbuvir-and-velpatasvir-for-hepatitis-c-virus-infection-in-people-with-recent-injection-drug-use-simplify-an-open-label-single-arm-phase-4-multicentre-trial
#3
Jason Grebely, Olav Dalgard, Brian Conway, Evan B Cunningham, Philip Bruggmann, Behzad Hajarizadeh, Janaki Amin, Julie Bruneau, Margaret Hellard, Alain H Litwin, Philippa Marks, Sophie Quiene, Sharmila Siriragavan, Tanya L Applegate, Tracy Swan, Jude Byrne, Melanie Lacalamita, Adrian Dunlop, Gail V Matthews, Jeff Powis, David Shaw, Maria Christine Thurnheer, Martin Weltman, Ian Kronborg, Curtis Cooper, Jordan J Feld, Chris Fraser, John F Dillon, Phillip Read, Ed Gane, Gregory J Dore
BACKGROUND: Despite revised guidelines that no longer exclude people who inject drugs (PWID) from treatment for hepatitis C virus (HCV) infection, many clinicians are reluctant to treat recent PWID. This study aimed to evaluate the efficacy of sofosbuvir and velpatasvir therapy in people with chronic HCV infection and recent injection drug use. METHODS: In this open-label, single-arm phase 4 trial (SIMPLIFY), we recruited participants with recent injection drug use (past 6 months) and chronic HCV genotype 1-6 infection from seven countries (19 sites)...
January 5, 2018: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29297968/comparison-between-core-shell-and-totally-porous-particle-stationary-phases-for-fast-and-green-lc-determination-of-five-hepatitis-c-antiviral-drugs
#4
Adel Ehab Ibrahim, Hisham Hashem, Magda Elhenawee, Hanaa Saleh
The performances of core-shell 2.7 μm and fully porous sub-2 μm particles packed in narrow diameter columns were compared under the same chromatographic conditions. The stationary phases were compared for fast separation and determination of five new antiviral drugs; daclatasvir, sofosbuvir, velpatasvir, simeprevir and ledipasvir. The gradient elution was done using ethanol as green organic modifier which is more environmentally friendly. Although both columns provided very good resolution of the five drugs, core-shell particles had proven to be of better efficiency...
January 3, 2018: Journal of Separation Science
https://www.readbyqxmd.com/read/29273372/preischemic-transfusion-of-old-packed-rbcs-exacerbates-early-phase-warm-hepatic-ischemia-reperfusion-injury-in-rats
#5
Eun Kyung Choi, Jongyoon Baek, Sangyoung Park, Suk Hwan Baek, Joon-Hyuk Choi, Chae Hoon Lee, Eon-Gi Sung, Daelim Jee
BACKGROUND: Hepatic innate immune cells are considered to play a central role in the early phase of hepatic ischemia reperfusion (IR) injury. Transfusion of old red blood cells (RBCs) is known to prime immune cells, and transfusion before IR may exacerbate liver injury because of the expected hyperresponsiveness of immune cells. MATERIALS AND METHODS: Twenty-four Sprague-Dawley rats were divided into four groups: sham operation (Sham); hepatic IR only (IR Control); and two transfusion groups, preischemic (Pre-T) and postischemic (Post-T), in which allogeneic RBCs stored for 2 weeks were transfused before hepatic IR or after reperfusion, respectively...
February 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29216924/dengue-hemorrhagic-fever-complicated-with-acute-liver-failure-a-case-report
#6
Chamara Dalugama, Indika Bandara Gawarammana
BACKGROUND: Dengue is a common arboviral infection with a clinically diverse spectrum of presentations. Although hepatic dysfunction is commonly identified in patients will dengue illness, acute liver failure is rare. The etiopathogenesis of hepatic dysfunction is multifactorial and related to direct viral invasion of hepatocytes, immunological factors and hypoxia particularly in cases of shock in dengue hemorrhagic fever. Ideal management of dengue-related hepatic dysfunction and acute liver failure is still debated...
December 8, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29193051/interaction-between-tobacco-smoking-and-hepatitis-b-virus-infection-on-the-risk-of-liver-cancer-in-a-chinese-population
#7
Xing Liu, Aileen Baecker, Ming Wu, Jin-Yi Zhou, Jie Yang, Ren-Qiang Han, Pei-Hua Wang, Zi-Yi Jin, Ai-Min Liu, Xiaoping Gu, Xiao-Feng Zhang, Xu-Shan Wang, Ming Su, Xu Hu, Zheng Sun, Gang Li, Lina Mu, Na He, Liming Li, Jin-Kou Zhao, Zuo-Feng Zhang
Although tobacco smoking has been reported as a risk factor for liver cancer, few studies have specifically explored the association among Chinese females and the potential interaction between smoking and other risk factors. A population-based case-control study was conducted and 2,011 liver cancer cases and 7,933 healthy controls were enrolled in Jiangsu, China from 2003 to 2010. Epidemiological data were collected, and serum HBsAg and anti-HCV antibody were measured. Unconditional logistic regression was used to examine association and potential interaction, while semi-Bayes method was employed to make estimates more conservative...
November 28, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29128360/golga2-loss-causes-fibrosis-with-autophagy-in-the-mouse-lung-and-liver
#8
Sungjin Park, Sanghwa Kim, Minjung Kim, Youngeun Hong, Ah Young Lee, Hyunji Lee, Quangdon Tran, Minhee Kim, Hyeonjeong Cho, Jisoo Park, Kwang Pyo Kim, Jongsun Park, Myung-Haing Cho
Autophagy is a biological recycling process via the self-digestion of organelles, proteins, and lipids for energy-consuming differentiation and homeostasis. The Golgi serves as a donor of the double-membraned phagophore for autophagosome assembly. In addition, recent studies have demonstrated that pulmonary and hepatic fibrosis is accompanied by autophagy. However, the relationships among Golgi function, autophagy, and fibrosis are unclear. Here, we show that the deletion of GOLGA2, encoding a cis-Golgi protein, induces autophagy with Golgi disruption...
November 8, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29125712/lipid-metabolism-and-functional-assessment-of-discarded-human-livers-with-steatosis-undergoing-24-hours-normothermic-machine-perfusion
#9
Qiang Liu, Ahmed Nassar, Laura Buccini, Giuseppe Iuppa, Basem Soliman, Daniele Pezzati, Ahmed Hassan, Matthew Blum, William Baldwin, Ana Bennett, Kenneth Chavin, Toshihiro Okamoto, Teresa Diago Uso, John Fung, Kareem Abu-Elmagd, Charles Miller, Cristiano Quintini
Normothermic machine perfusion (NMP) is an emerging technology to preserve liver allografts more effectively than cold storage (CS). However, little is known about the effect of NMP on steatosis, and the markers indicative of hepatic quality during NMP. To address these points we perfused 10 discarded human livers with oxygenated NMP for 24 hours after 4-6 hours of CS. All livers had variable degree of steatosisat at baseline. The perfusate consisted of packed red blood cells and fresh frozen plasma. Perfusate analysis showed an increase in triglyceride levels from the 1st hour (median 127 mg/dL; interquartile range 95-149) to 24th hour of perfusion (203;171-304) (p=0...
November 10, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29075518/usefulness-of-ultrasonography-in-the-diagnosis-of-hematoma-after-primary-hip-arthroplasty
#10
Jerzy Białecki, Paweł Bartosz, Wojciech Marczyński, Jan Zając
INTRODUCTION: To date, suction drainage has been routinely used after hip joint replacement. Currently, the validity of this practice is questioned in the literature. Hematoma is a risk factor of periprosthetic infection. Post-operative ultrasonography enables precise assessment of hip joint hematoma. AIM: The aim of the study was to evaluate the usefulness of hip joint ultrasonography with respect to the validity of using suction drainage after primary hip arthroplasty...
September 2017: Journal of Ultrasonography
https://www.readbyqxmd.com/read/29048838/-simultaneous-determination-of-plasma-indole-and-skatole-in-pregnant-women-with-hepatitis-b-virus-infection-by-high-performance-liquid-chromatography
#11
Linlin Deng, Qianna Zhen, Jieying Gao, Mingchao Jin, Min Ding, Biao Xu
A high performance liquid chromatographic (HPLC) method with fluorescence detection (FD) was established to simultaneously determine plasma indole and skatole. Plasma samples were pretreated by liquid-liquid extraction. Chromatographic separation was accomplished on a Shim-Pack VP-ODS column (150 mm×4. 6 mm, 4.6 μ m) using an isocratic mixture of 15 mmol/L sodium dihydrogen phosphate solution and methanol (40:60, v/v). The fluorescence excitation and emission wavelengths were 274 nm and 340 nm, respectively...
July 8, 2017: Se Pu, Chinese Journal of Chromatography
https://www.readbyqxmd.com/read/28983163/angioleiomyoma-of-uterus-masquerading-as-malignant-ovarian-tumor
#12
Sweta Singh, Monalisha Naik, Narbadyswari Deep Bag, Susama Patra
Uterine angioleiomyoma is rare. A 40-year-old nulliparous woman presented with heavy menstrual bleeding (HMB) for the past 2 years and mass per abdomen with severe dysmenorrhea for three cycles. She had received 8 units of packed cell transfusion outside. Clinical examination revealed a huge 32-week-sized abdominopelvic mass with irregular margins. Ultrasonography (USG) of the abdomen and pelvis showed a large solid cystic mass on the right side of the abdomen with a well-defined hypoechoeic rounded lesion of size 5...
July 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28982041/-affording-new-approaches-to-couples-who-inject-drugs-a-novel-fitpack-design-for-hepatitis-c-prevention
#13
Suzanne Fraser, Carla Treloar, Sandra Gendera, Jake Rance
BACKGROUND: In the West, hepatitis C is predominantly transmitted via the sharing of contaminated drug-injecting equipment. Although the majority of this sharing occurs between sexual partners, the responsibility for avoiding transmission has long been conceived as an individual responsibility, with prevention measures such as the distribution of sterile injecting equipment such as injecting packs ('fitpacks') aimed at individuals without regard for the social contexts of injecting. In this article we draw on the work of Bruno Latour to reconceptualise the fitpack...
October 2, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28981535/predictors-of-transitions-in-frailty-severity-and-mortality-among-people-aging-with-hiv
#14
Thomas D Brothers, Susan Kirkland, Olga Theou, Stefano Zona, Andrea Malagoli, Lindsay M K Wallace, Chiara Stentarelli, Cristina Mussini, Julian Falutz, Giovanni Guaraldi, Kenneth Rockwood
BACKGROUND: People aging with HIV show variable health trajectories. Our objective was to identify longitudinal predictors of frailty severity and mortality among a group aging with HIV. METHODS: Exploratory analyses employing a multistate transition model, with data from the prospective Modena HIV Metabolic Clinic Cohort Study, based in Northern Italy, begun in 2004. Participants were followed over four years from their first available visit. We included all 963 participants (mean age 46...
2017: PloS One
https://www.readbyqxmd.com/read/28971606/methionine-and-vitamin-b-complex-ameliorate-antitubercular-drugs-induced-toxicity-in-exposed-patients
#15
Kennedy I Amagon, Olufunsho Awodele, Abidemi J Akindele
Tuberculosis therapy utilizes drugs that while effective cause treatment-related toxicity. Modulation of antitubercular drugs-induced toxicity by methionine and vitamin B-complex in patients was evaluated. 285 treatment-naïve tuberculosis patients at the Chest Clinics of Infectious Diseases Hospital, Yaba and General Hospital, Lagos in Lagos, Nigeria was prospectively recruited and allotted into test (antitubercular medicines, methionine and vitamin B-complex) and control groups (antitubercular medicines)...
October 2017: Pharmacology Research & Perspectives
https://www.readbyqxmd.com/read/28970702/generic-direct-acting-antivirals-in-treatment-of-chronic-hepatitis-c-infection-in-patients-of-thalassemia-major
#16
Aabha Nagral, Smita Sawant, Nishtha Nagral, Pathik Parikh, Priya Malde, Rashid Merchant
BACKGROUND: There is no published data of treating hepatitis C in thalassemia major patients with any sofosbuvir based direct acting antivirals (DAAs). This study was performed to determine the efficacy and safety of these regimes using generic drugs in the thalassemia major population. METHODS: In this observational study, 902 patients of thalassemia major from five transfusion centres in Mumbai were screened for HCV antibody. Of the 120 positive patients, HCV RNA was detected in 50%...
September 2017: Journal of Clinical and Experimental Hepatology
https://www.readbyqxmd.com/read/28926166/continuous-production-of-ursodeoxycholic-acid-using-two-cascade-reactors-with-coimmobilized-enzymes
#17
Ming-Min Zheng, Fei-Fei Chen, Hao Li, Chun-Xiu Li, Jian-He Xu
Ursodeoxycholic acid (UDCA) is an effective drug for the treatment of hepatitis. In this study, 7α-hydroxysteroid dehydrogenase (7α-HSDH) and lactate dehydrogenase (LDH), as well as 7β-HSDH and glucose dehydrogenase (GDH), were co-immobilized onto an epoxy-functionalized resin (ES-103) for catalyzing the synthesis of UDCA from chenodeoxycholic acid (CDCA). Through optimizing the immobilization pH, time and the loading ratio of enzymes to resin, the specific activities of immobilized LDH-7αHSDH@ES-103 and 7βHSDH-GDH@ES-103 were 43...
September 19, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/28911627/assessment-of-the-pharmacokinetics-removal-rate-of-hemodialysis-and-safety-of-lactulose-in-hemodialysis-patients
#18
Cheng-Jui Lin, Chi-Feng Pan, Sy-Yeuan Ju, Hsuan-Kai Tzeng, Shen-Wei Chen, Jhu-Ting Syu, Chih-Jen Wu
Lactulose is often used to treat hepatic encephalopathy or constipation, and also exhibits benefits to chronic renal insufficiency due to reduce nitrogen-related products in serum. The present study investigated the pharmacokinetics of lactulose, its removal rate through dialysis, and safety by administering lactulose 6.5 g (Lagnos Jelly Divided Pack 16.05 g) orally to six hemodialysis patients who resided in Taiwan. As a result, the means of maximum plasma concentrations (Cmax) and Time to reach Cmax (Tmax) were 3090 ± 970 ng/mL and 6...
October 2016: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28877812/spontaneous-hepatic-hemorrhage-a-single-institution-s-16-year-experience
#19
Armando Rosales, Florencia G Que
Spontaneous hemorrhage from hepatic tumors is an uncommon but serious complication. Recently, interventional radiologic (IR) techniques are being used increasingly in the management of these patients. We report our 16-year experience in managing spontaneous hemorrhage from liver tumors. Twenty-six consecutive patients were diagnosed with spontaneous liver hemorrhage between 1995 and 2011. Initial management was operative in eight, IR in six, and supportive in 12 patients. Of those managed operatively, five were segmentectomies; one hemihepatectomy; one wedge resection; and one packing who later died from coagulopathy...
November 1, 2016: American Surgeon
https://www.readbyqxmd.com/read/28863378/right-hepatectomy-after-spontaneous-hepatic-rupture-in-a-patient-with-preeclampsia-a-case-report
#20
Carlos A Millan, Juan C Forero
INTRODUCTION: Spontaneous hepatic rupture associated with preecalmpsia or HELLP syndrome is a rare and life threatining event, only 200 cases have been reported in the literature. PRESENTATION OF CASE: We present a case of a 31 year old female with 28 weeks of gestation that presented with acute abdominal pain, elevated blood pressure and altered liver enzymes an abdominal ultrasound that showed a subcapsular hematoma occupying the whole right lobe and free abdominal fluid, she required emergent laparotomy, C-section, hepatic packing, followed by angioembolization and finally right hepatectomy...
2017: International Journal of Surgery Case Reports
keyword
keyword
71483
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"