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https://www.readbyqxmd.com/read/28070743/cardiac-ct-angiography-ccta-predicts-left-atrial-appendage-occluder-device-size-and-procedure-outcome
#1
Orly Goitein, Noam Fink, Ilan Hay, Elio Di Segni, Victor Guetta, David Goitein, Yafim Brodov, Eli Konen, Michael Glikson
AIM: To investigate the role of cardiac CT angiography (CCTA) in predicting optimal left atrial appendage (LAA) occluder size and procedure outcome. METHODS AND RESULTS: Thirty-six patients underwent pre-procedural CCTA. CCTA and TEE LAA orifice diameters and perimeters were compared with the implanted device size. CCTA 3D configuration was correlated with procedure outcome. Watchman™ device (N = 18): diameters were 21 ± 4, 26 ± 5 and 25 ± 3 mm for TEE, CCTA and inserted device, respectively...
January 9, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28013284/ct-sizing-for-left-atrial-appendage-closure-is-associated-with-favourable-outcomes-for-procedural-safety
#2
Adil Rajwani, Adam J Nelson, Masoumeh G Shirazi, Patrick J S Disney, Karen S L Teo, Dennis T L Wong, Glenn D Young, Stephen G Worthley
AIMS: We evaluated the utility of computerized tomography (CT) with respect to sizing work-up for percutaneous left atrial appendage (LAA) closure, and implications for procedural safety and outcomes. METHODS AND RESULTS: Contrast-enhanced multi-detector CT was routinely conducted to guide sizing for LAA closure in addition to transoesophageal echocardiography (TOE). Procedural safety and efficacy were prospectively assessed. Across 73 consecutive cases there were no device-related procedural complications, and no severe leaks...
December 24, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/27969998/tct-623-predictors-of-mace-with-the-watchman-device-an-intention-to-treat-analysis-in-a-real-world-experience
#3
Mohamad Lazkani, Shishir Murarka, Divya Ratan Verma, Timothy Byrne, Ashish Sadhu, Marwan Bahu, Akil Loli, Haidar Yassin, Yash Pershad, Ashish Pershad
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969997/tct-621-left-atrial-appendage-characteristics-evaluated-by-computed-tomography-following-closure-with-watchman-device
#4
Daniel Kupsky, Dee Dee Wang, Marvin Eng, Thomas Song, Milan Pantelic, Jeffrey Nadig, Adam Greenbaum, William O'Neill
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969993/tct-618-safety-and-efficacy-of-left-atrial-appendage-closure-with-the-watchman-device-in-patients-older-than-85-years-old-data-from-the-prospective-ewolution-registry
#5
Ignacio Cruz Gonzalez, Hüseyin Ince, Boris Schmidt, User, Leif-Hendrik Boldt, Robin Molitoris, Jean-Benoit Thambo, Christof Wald, Kenneth Stein, Lucas Boersma
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969992/tct-615-do-patients-with-ckd-benefit-from-left-atrial-appendage-closure-laac-with-watchman-insights-from-protect-af
#6
Miguel Valderrabano, Matthew Price, Vivek Reddy, Maurice Buchbinder, David Holmes, Horst Sievert, Zoltan Turi, Nicole Gordon, Chris Mullin, Peter Sick, Patricia Best
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969990/tct-616-medium-term-safety-and-efficacy-of-left-atrial-appendage-closure-using-the-watchman%C3%A2-device-in-260-patients-from-single-center
#7
Jiangtao Yu, Xin Xue, Shaofeng Guan, Adam Fazakas, Laszlo Halmagyi, Fanzhou Cheng, Erich Dünninger
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969610/tct-26-long-term-event-rates-for-left-atrial-appendage-closure-with-watchman-protect-af-5-year-and-prevail-3-year-follow-up
#8
Vivek Reddy, Matthew Price, Miguel Valderrabano, Jose Sanchez, Shephal Doshi, Nicole Gordon, David Holmes
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27943538/catheter-ablation-for-atrial-fibrillation-in-patients-with-watchman%C3%A2-left-atrial-appendage-occlusion-device-results-from-a-multicenter-registry
#9
Mohit K Turagam, Madhav Lavu, Muhammad R Afzal, Venkat Vuddanda, Mohammad-Ali Jazayeri, Valay Parikh, Donita Atkins, Sudharani Bommana, Luigi DI Biase, Rodney Horton, Rong Bai, Vijay Swarup, Jie Cheng, Andrea Natale, Dhanunjaya Lakkireddy
BACKGROUND: There have been an increasing number of atrial fibrillation (AF) patients with Watchman® left atrial appendage occlusion (LAAO) device, requiring catheter ablation (CA) for maintenance of normal sinus rhythm. In this study, we describe our experience with the feasibility and safety of CA in patients with a preexisting Watchman LAAO device. METHODS: This was a retrospective multicenter AF registry of 60 patients with Watchman® LAAO device who underwent CA for AF...
December 12, 2016: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/27931603/run-with-the-hare-and-hunt-with-the-hounds-watchman-device-surgical-resection-in-the-setting-of-recurrent-device-related-thrombi-in-a-patient-with-bleeding-diathesis
#10
Catherine O'Hara, Gilles E O'Hara, Frédéric Jacques, Jean Champagne, Maryse Lemyre, Lyne Charbonneau, Kim O'Connor, Mathieu Bernier, Jonathan Beaudoin, Josep Rodés-Cabau, Jean-Michel Paradis
No abstract text is available yet for this article.
December 12, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27916590/retrospective-cohort-study-examining-reduced-intensity-and-duration-of-anticoagulant-and-antiplatelet-therapy-following-left-atrial-appendage-occlusion-with-the-watchman-device
#11
Matthew K Tung, Satish Ramkumar, James D Cameron, Benjamin Pang, Nitesh Nerlekar, Emily Kotschet, Jeffrey Alison
BACKGROUND: Anticoagulant and antiplatelet therapy are recommended following WATCHMAN implantation (45 days and 6 months) to reduce the risk of embolic events. These patients are often also at high risk of recurrent bleeding complications. We aimed to assess the safety of reduced duration of treatment with anticoagulant and antiplatelet therapy in the early post implant period. METHODS: This was a retrospective cohort study assessing the duration of antiplatelet and anticoagulant therapy in 47 consecutive patients following WATCHMAN implant...
November 15, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27898435/percutaneous-left-atrial-appendage-closure-current-state-of-the-art
#12
Mohammad-Ali Jazayeri, Venkat Vuddanda, Valay Parikh, Dhanunjaya R Lakkireddy
PURPOSE OF REVIEW: The authors reviewed the seminal and more recent literature surrounding the major modalities for percutaneous left atrial appendage closure used in contemporary practice, with particular emphasis on safety and efficacy, technical challenges, and future developments. RECENT FINDINGS: Along with the continued practice of surgical left atrial appendage closure, which has evolved substantially with the advent of clipping techniques, a number of percutaneous methods have been developed to close the left atrial appendage with endocardial, epicardial, and hybrid approaches...
January 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/27884358/application-of-3-dimensional-computed-tomographic-image-guidance-to-watchman-implantation-and-impact-on%C3%A2-early-operator-learning-curve-single-center-experience
#13
Dee Dee Wang, Marvin Eng, Daniel Kupsky, Eric Myers, Michael Forbes, Mehnaz Rahman, Mohammad Zaidan, Sachin Parikh, Janet Wyman, Milan Pantelic, Thomas Song, Jeff Nadig, Patrick Karabon, Adam Greenbaum, William O'Neill
OBJECTIVES: The aim of this study was to examine the impact of 3-dimensional (3D) computed tomographic (CT) guided procedural planning for left atrial appendage (LAA) occlusion on the early operator WATCHMAN learning curve. BACKGROUND: Traditional WATCHMAN implantation is dependent on 2-dimensional transesophageal echocardiographic (TEE) sizing and intraprocedural guidance. METHODS: LAA occlusion with the WATCHMAN device was performed in 53 patients...
November 28, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27862233/transesophageal-echocardiographic-diagnosis-of-a-watchman-left-atrial-appendage-closure-device-thrombus-10%C3%A2-years-following-implantation
#14
Shariq Shamim, Anthony Magalski, Adnan K Chhatriwalla, Keith B Allen, Kenneth C Huber, Michael L Main
Left atrial appendage closure with the WATCHMAN device is an alternative to chronic oral anticoagulation for thromboembolic prophylaxis in atrial fibrillation patients. Left atrial device-related thrombus (DRT) has been described in the first year after implant with an incidence of ~6%. A 79-year-old man underwent WATCHMAN device placement in 2006. Routine protocol specified follow-up transesophageal echocardiograms (TEE) at 6 weeks, 6 months, and 1 year following implant showed no evidence for DRT or peri-device flow...
November 16, 2016: Echocardiography
https://www.readbyqxmd.com/read/27816552/post-fda-approval-initial-us-clinical-experience-with-watchman-left-atrial-appendage-closure-for-stroke-prevention-in-atrial-fibrillation
#15
Vivek Y Reddy, Douglas N Gibson, Saibal Kar, William O'Neill, Shephal K Doshi, Rodney P Horton, Maurice Buchbinder, Nicole T Gordon, David R Holmes
BACKGROUND: Left atrial appendage closure (LAAC) using the Watchman device was FDA-approved as a stroke prevention alternative to warfarin for patients with non-valvular atrial fibrillation. However, clinical decision-making is confounded by the fact that while LAAC avoids the anticoagulant-related lifetime risk of bleeding, implantation is associated with up-front complications. Thus, enthusiasm for LAAC as a treatment option has been appropriately tempered, particularly as the therapy is introduced beyond the clinical trial sites into general clinical practice...
October 27, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27815629/pulmonary-artery-perforation-and-coronary-air-embolism-two-fatal-outcomes-in-percutaneous-left-atrial-appendage-occlusion
#16
J Zwirner, R Bayer, C Hädrich, A Bollmann, N Klein, J Dreßler, B Ondruschka
Percutaneous left atrial appendage (LAA) closure is a routinely performed method to reduce the risk of stroke in patients suffering from atrial fibrillation, when an oral anticoagulation is no longer indicated due to relevant bleeding complications. Currently, the Amplatzer Amulet and the Watchman system are two equally used systems. While there is an acute success rate of more than 95 per cent for this intervention, several minor and major complications such as pericardial effusions, air embolism, vascular lesions in proximity to the heart or even death can occur...
January 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/27771552/use-of-non-warfarin-oral-anticoagulants-instead-of-warfarin-during-left-atrial-appendage-closure-with-the-watchman-device
#17
Yoshinari Enomoto, Varuna K Gadiyaram, Carola Gianni, Rodney P Horton, Chintan Trivedi, Sanghamitra Mohanty, Luigi Di Biase, Amin Al-Ahmad, J David Burkhardt, Arvin Narula, Gwen Janczyk, Matthew J Price, Muhammad R Afzal, Moustapha Atoui, Matthew Earnest, Vijay Swarup, Shephal K Doshi, Sarina van der Zee, Rebecca Fisher, Dhanunjaya R Lakkireddy, Douglas N Gibson, Andrea Natale, Vivek Y Reddy
BACKGROUND: In the stroke prevention trials of left atrial appendage closure with the Watchman device (Boston Scientific), a postimplantation antithrombotic regimen of 6 weeks of warfarin was used. OBJECTIVE: Given the clinical complexity of warfarin use, the purpose of this study was to study the relative feasibility and safety of using non-warfarin oral anticoagulants (NOACs) instead of warfarin during the peri- and initial postimplantation periods after Watchman implantation...
January 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/27745964/characterization-of-cerebrovascular-events-after-left-atrial-appendage-occlusion
#18
Xavier Freixa, Laura Llull, Sameer Gafoor, Ignacio Cruz-Gonzalez, Samera Shakir, Heyder Omran, Sergio Berti, Gennaro Santoro, Joelle Kefer, Ulf Landmesser, Jens Erik Nielsen-Kudsk, Prapa Kanagaratnam, Fabian Nietlispach, Steffen Gloekler, Adel Aminian, Paolo Danna, Marco Rezzaghi, Friederike Stock, Miroslava Stolcova, Luis Paiva, Marco Costa, Xavier Millán, Reda Ibrahim, Tobias Tichelbäcker, Wolfgang Schillinger, Jai-Wun Park, Horst Sievert, Bernhard Meier, Apostolos Tzikas
Cardioembolic strokes are generally more lethal and disabling than other source of strokes. Data from PROTECT AF (Watchman Left Atrial Appendage Closure Technology for Embolic Protection in Patients With Atrial Fibrillation) suggest that strokes after left atrial appendage occlusion (LAAO) with the Watchman device are less disabling than those in the warfarin group. No data assessing the severity of strokes after LAAO with the AMPLATZER Cardiac Plug (ACP) are available. The objective of the study was to evaluate the severity of cerebrovascular events after LAAO with the ACP in a population mostly characterized by an absolute or relative contraindication to oral anticoagulation...
September 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27706224/comparison-of-approaches-for-stroke-prophylaxis-in-patients-with-non-valvular-atrial-fibrillation-network-meta-analyses-of-randomized-controlled-trials
#19
Navkaranbir S Bajaj, Rajat Kalra, Nirav Patel, Taimoor Hashim, Hemant Godara, Sameer Ather, Garima Arora, Tilak Pasala, Thomas T Whitfield, David C McGiffin, Mustafa I Ahmed, Steven G Lloyd, Nita A Limdi, Pankaj Arora
BACKGROUND: Multiple novel oral anticoagulants and left atrial appendage closure devices (WATCHMAN) have been tested against dose-adjusted vitamin K antagonists in randomized controlled trials for stroke prophylaxis in non-valvular atrial fibrillation. No direct comparisons of these strategies are available from randomized controlled trials. We conducted the current analyses by combining efficacy and safety characteristics of all FDA approved stroke prophylaxis treatment strategies for patients with non-valvular atrial fibrillation...
2016: PloS One
https://www.readbyqxmd.com/read/27696317/left-atrial-appendage-closure-for-stroke-prevention-in-atrial-fibrillation
#20
REVIEW
Erin A Fender, Jawad G Kiani, David R Holmes
PURPOSE OF REVIEW: Anticoagulant therapy effectively reduces the incidence of stroke in patients with atrial fibrillation (AF) but is underutilized and frequently contraindicated. The left atrial appendage (LAA) is the primary site of thrombus formation in AF patients. Surgical and percutaneous appendage closure has been evaluated as a site-specific therapy to reduce systemic thromboembolism. RECENT FINDINGS: We will review LAA closure techniques, examine recent outcome data, and discuss the indications for, and potential complications of, each approach...
November 2016: Current Atherosclerosis Reports
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