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Solitary pulmonary nodule

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https://www.readbyqxmd.com/read/28932562/standardized-uptake-value-and-radiological-density-attenuation-as-predictive-and-prognostic-factors-in-patients-with-solitary-pulmonary-nodules-our-experience-on-1-592-patients
#1
Duilio Divisi, Mirko Barone, Luca Bertolaccini, Gaetano Rocco, Piergiorgio Solli, Roberto Crisci
BACKGROUND: Multislice computed tomography (MSCT) increased detection of solitary pulmonary nodules (SPNs), changing the management based on radiological and clinical factors. When 18-fluorine fluorodeoxyglucose positron emission tomography combined with computed tomography ((18)F-FDG-PET/CT) was considered for the evaluation of nodules, the maximum standardized uptake value (SUVmax) more than 2.5 is used frequently as a cut off for malignancy. The purpose of this study is to evaluate SUVmax PET/CT and pulmonary attenuation patterns at MSCT in patients with SPN according to morphological and pathological characteristics of the lesion...
August 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28910817/the-lung-in-dysregulated-states-of-humoral-immunity
#2
Yurdagül Uzunhan, Florence Jeny, Marianne Kambouchner, Morgane Didier, Diane Bouvry, Hilario Nunes, Jean-François Bernaudin, Dominique Valeyre
In common variable immunodeficiency, lung manifestations are related to different mechanisms: recurrent pneumonias due to encapsulated bacteria responsible for diffuse bronchiectasis, diffuse infiltrative pneumonia with various patterns, and lymphomas, mostly B cell extranodal non-Hodgkin type. The diagnosis relies on significant serum Ig deficiency and the exclusion of any primary or secondary cause. Histopathology may be needed. Immunoglobulin (IgG) replacement is crucial to prevent infections and bronchiectasis...
September 15, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28892401/pulmonary-cryptococcus-presenting-as-a-solitary-pulmonary-nodule
#3
Sivakumar Sudhakaran, Lara Bashoura, John Stewart, Diwakar D Balachandran, Saadia A Faiz
No abstract text is available yet for this article.
September 11, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28887727/predictors-of-primary-lung-cancer-in-a-solitary-pulmonary-lesion-after-a-previous-malignancy
#4
Akie Nakadate, Masashi Nakadate, Yasunori Sato, Tassei Nakagawa, Katsuya Yoshida, Yoshio Suzuki, Yukihiro Yoshida
OBJECTIVE: A solitary pulmonary lesion in patients with a history of malignancy may be either primary lung cancer or a metastatic lung tumor or benign nodule. We retrospectively examined the preoperative predictive factors for determining the type of pathology. METHODS: We used an exact logistic regression analysis to identify radiological and clinical predictors of primary lung cancer. The study included 187 patients who underwent pulmonary resection for a solitary pulmonary lesion and had received previous treatment for a malignancy...
September 8, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28874904/extrahepatic-metastasis-of-hepatocellular-carcinoma-arising-from-a-hepatic-adenoma-without-concurrent-intrahepatic-recurrence
#5
N Poddar, R Ramlal, S Ravulapati, S M Devlin, S Gadani, C I Vidal, D Cao, A S Befeler, J Lai
Hepatocellular carcinoma (hcc) arising from a hepatic adenoma is a rare phenomenon accounting for fewer than 5% of hcc cases; it seldom recurs after resection of the primary tumour. We report a case of extrahepatic metastasis of hcc arising from a hepatic adenoma that presented as a solitary sternal metastasis without any evidence of intrahepatic recurrence. Our patient was initially treated with radiation therapy and bland embolization, without response. Subsequently, the patient developed progressive disease while taking sorafenib...
August 2017: Current Oncology
https://www.readbyqxmd.com/read/28871589/metastasising-leiomyoma-of-the-uterus-with-pulmonary-involvement-case-report
#6
Marta Maskey-Warzęchowska, Magdalena Chojnowska, Konrad Ptaszyński, Renata Rubinsztajn, Marzena Padzik-Moczydłowska, Rafał Krenke
Benign metastasising leiomyoma (BML) is characterised by extrauterine smooth muscle tumours in women after surgical treatment for uterine leiomyoma. Usually manifested as solitary or multiple focal lesions in various organs, it imposes a scrutinous diagnostic work-up to exclude a malignant disease and requires confirmation in microscopic examination of the extrauterine focus. The authors present a case of a 56-year-old woman with BML manifesting as bilateral multiple pulmonary nodules, with a tentative diagnosis of a disseminated malignant disease of mesenchymal origin...
2017: Advances in Respiratory Medicine
https://www.readbyqxmd.com/read/28839156/diagnostic-classification-of-solitary-pulmonary-nodules-using-dual-time-18-f-fdg-pet-ct-image-texture-features-in-granuloma-endemic-regions
#7
Song Chen, Stephanie Harmon, Timothy Perk, Xuena Li, Meijie Chen, Yaming Li, Robert Jeraj
Lung cancer, the most commonly diagnosed cancer worldwide, usually presents as solid pulmonary nodules (SPNs) on early diagnostic images. Classification of malignant disease at this early timepoint is critical for improving the success of surgical resection and increasing 5-year survival rates. (18)F-fluorodeoxyglucose ((18)F-FDG) PET/CT has demonstrated value for SPNs diagnosis with high sensitivity to detect malignant SPNs, but lower specificity in diagnosing malignant SPNs in populations with endemic infectious lung disease...
August 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28834599/the-value-of-macrophage-inhibitory-cytokine-1-level-in-differentiating-benign-from-malignant-solitary-pulmonary-nodules
#8
Chun Hua Xu, Jin Shan Xue, Xiu Wei Zhang, Li Ke Yu, Yong Lin
INTRODUCTION: Macrophage inhibitory cytokine-1 (MIC-1), a transforming growth factor-β superfamily cytokine, is involved in tumor pathogenesis, and its measurement can be used as a clinical tool for the diagnosis of a wide range of cancers. OBJECTIVES: The aim of this study was to explore the diagnostic value of serum MIC-1 in patients with solitary pulmonary nodules (SPNs). METHODS: Serum specimens from 158 malignant SPN patients, 110 benign SPN patients, along with 120 healthy volunteers...
August 23, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28830222/pulmonary-mucosa-associated-lymphoid-tissue-lymphoma-18f-fdg-pet-ct-and-ct-findings-in-28-patients
#9
Domenico Albano, Andrea Borghesi, Giovanni Bosio, Mattia Bertoli, Roberto Maroldi, Raffaele Giubbini, Francesco Bertagna
OBJECTIVE: The aim of the study was to evaluate the computed tomography (CT) and fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) imaging findings of lung mucosa associated lymphoid tissue (MALT) lymphoma. METHODS: Twenty eight patients with histologically-confirmed pulmonary MALT lymphoma who underwent a chest CT and 18F-FDG PET/CT for staging were retrospectively analyzed. The CT images were evaluated to determine morphological pattern of appearance, laterality, localization, number, size, presence of thoracic lymphadenopaties and secondary/combined findings...
August 22, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28825886/use-of-volumetry-for-lung-nodule-management-theory-and-practice
#10
REVIEW
Anand Devaraj, Bram van Ginneken, Arjun Nair, David Baldwin
A consistent feature of many lung nodule management guidelines is the recommendation to evaluate nodule size by using diameter measurements and electronic calipers. Traditionally, the use of nodule volumetry applications has primarily been reserved for certain lung cancer screening trials rather than clinical practice. However, even before the first nodule management guidelines were published more than a decade ago, research has been ongoing into the use of nodule volumetry as a means of measuring nodule size, and this research has accelerated in recent years...
September 2017: Radiology
https://www.readbyqxmd.com/read/28811947/solitary-skull-metastasis-as-the-first-presentation-of-a-metachronous-primary-lung-cancer-in-a-survivor-from-pancreatic-cancer
#11
Ali Altalhy, Yazid Maghrabi, Zuhoor Almansouri, Saleh S Baeesa
Skull metastasis from lung cancer is relatively common, yet the first presentation for this malignant disease is a rare occurrence. We herein report a case of a 54-year-old female, who had a good outcome following Whipple procedure for periampullary adenocarcinoma five years before her current presentation. During a routine follow-up, she was found to have a slowly progressive painless right parietal swelling. The systemic screening workup revealed no abdominal disease, but a solitary pulmonary nodule was identified...
2017: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/28792116/management-of-indeterminate-pulmonary-nodules-1-cm-newly-detected-during-the-follow-up-of-nasopharyngeal-carcinoma-patients
#12
Chengrun Du, Caifeng Wan, Jianhui Ding, Guangyuan Zhang, Youwang Zhang, Chaosu Hu, Hongmei Ying
AIM: To investigate the management for the indeterminate pulmonary nodules newly detected during the follow-up for nasopharyngeal carcinoma (NPC) patients. METHODS: Indeterminate pulmonary lesions were identified by searching medical records of NPC patients, who were followed-up with thoracic CT between April 2008 and February 2014. Indeterminate pulmonary nodules were defined as opacities that may be solitary or multiple, which were <1 cm in size and not calcified...
August 9, 2017: Asia-Pacific Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28782248/risk-stratification-in-the-investigation-of-pulmonary-nodules-in-a-high-risk-cohort-pet-ct-outperforms-clinical-risk-prediction-algorithms
#13
Glenna Gibson, Aravind Ravi Kumar, Karin Steinke, Farzad Bashirzadeh, Rebecca Roach, Morgan Windsor, Robert Ware, David Fielding
BACKGROUND: Clinical prediction models and 18F-FDG-PET/CT are used for assessment of solitary pulmonary nodules (SPNs) however biopsy is still required before treatment which carries risk. AIM: To determine combined predictive benefit of one such model combined with modern PET/CT data to improve decision making about biopsy prior to treatment and possibly reduce costs. METHOD: Patients with a SPN undergoing 18F-FDG-PET/CT from January 2011-December 2012 were retrospectively identified...
August 7, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28768676/role-of-metastasectomy-and-chemotherapy-in-carcinoma-of-uterine-cervix
#14
Nasir Ali, Muhammad Atif Mansha, Ahmed Nadeem Abbasi, Bilal Mazhar Qureshi
Squamous cell carcinoma of uterine cervix is potentially a curable disease; however, many patients treated with definitive chemoradiotherapy develop distant metastases, with few of them having a single metastatic deposit. There are no guidelines for the treatment of patients with oligometastatic cervical cancer.We present a case of a patient with International Federation of Gynecology and Obstetrics (FIGO) Stage IIB squamous cell carcinoma of uterine cervix. She was successfully treated with concurrent chemoradiotherapy with definitive intent...
August 2, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28767602/iatrogenic-rupture-of-the-left-main-bronchus-secondary-to-repeated-surgical-lobe-torsion-during-double-lumen-tube-placement-a-case-report
#15
Zong Ming Jiang, Chu Zhang, Zhong Hua Chen
RATIONALE: Bronchial rupture is a rare but potentially life-threatening complication during double-lumen endobronchial tube placement. The rupture of the left main bronchus resulting from repeated surgical torsion is uncommon. PATIENT CONCERNS: A 70-year-old man with a history of chronic obstructive pulmonary disease (COPD), intermediate emphysema, chronic bronchitis, hypertension, type 2 diabetes mellitus, and L3-L4 lumbar intervertebral disc herniation. Chest x-ray and computed tomography revealed a solitary pulmonary nodule in the left lower lobe...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28756634/necrotizing-sarcoid-granulomatosis-a-distinctive-form-of-pulmonary-granulomatous-disease
#16
REVIEW
Georgia Karpathiou, Anna Batistatou, Panagiotis Boglou, Dimitrios Stefanou, Marios E Froudarakis
OBJECTIVES: To define the characteristics of necrotizing sarcoid granulomatosis (NGS) a very rare pulmonary disease hardly recognized by pulmonologists and pathologists. DATA SOURCE: PubMed was searched for the term necrotising or necrotizing sarcoid granulomatosis. STUDY SELECTION: All cases reported in the English literature were included. RESULTS: NGS is presented at all ages (range 8-68 years) with a median age of 42 years old...
July 29, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28744087/a-peek-into-the-future-of-radiology-using-big-data-applications
#17
Amit T Kharat, Shubham Singhal
Big data is extremely large amount of data which is available in the radiology department. Big data is identified by four Vs - Volume, Velocity, Variety, and Veracity. By applying different algorithmic tools and converting raw data to transformed data in such large datasets, there is a possibility of understanding and using radiology data for gaining new knowledge and insights. Big data analytics consists of 6Cs - Connection, Cloud, Cyber, Content, Community, and Customization. The global technological prowess and per-capita capacity to save digital information has roughly doubled every 40 months since the 1980's...
April 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/28743176/technique-of-skeletal-navigation-for-localizing-solitary-pulmonary-nodules
#18
Rui Mao, Weirong Shi, Donglai Chen, Xier Maimaiti Kadeer, Mu Li, Ke Fei, Chang Chen
We herein detail a novel method of skeletal navigation for localizing small solitary pulmonary nodules of 8-30 mm size and at a distance of less than 15 mm from visceral pleura. Thirty-four lesions found in 29 patients were successfully localized. All 34 target nodules first underwent wedge resections, and there were no cases of technical failure of the present method. This technique incurs no additional cost and complications as caused by other localization approaches. Additionally, this approach provides a backup method in cases of mark displacement...
July 25, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28734401/sampling-of-suspicious-solitary-pulmonary-nodules-electromagnetic-navigational-bronchoscopy-and-video-assisted-thoracoscopic-surgery
#19
Maria Lucia L Madariaga, Michael Lanuti
No abstract text is available yet for this article.
July 2017: Seminars in Roentgenology
https://www.readbyqxmd.com/read/28734400/sampling-of-suspicious-solitary-pulmonary-nodules-percutaneous-needle-biopsy-and-preoperative-localization
#20
Florian J Fintelmann, Amita Sharma
No abstract text is available yet for this article.
July 2017: Seminars in Roentgenology
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