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Solitary pulmonary nodule

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https://www.readbyqxmd.com/read/28522261/-pulmonary-hamartoma-as-an-example-of-solitary-pulmonary-nodule
#1
M Tejero-Mas, C Gato-Núñez, N Rivera-Jiménez, F Buitrago-Ramírez, A Palmerín-Donoso
No abstract text is available yet for this article.
May 15, 2017: Semergen
https://www.readbyqxmd.com/read/28493533/combination-diagnosis-of-multi-slice-spiral-computed-tomography-and-secretary-phospholipase-a2-iia-for-solitary-pulmonary-nodules
#2
Hongjun Hou, Zushan Xu, Hongsheng Zhang, Yan Xu
INTRODUCTION: This study was aimed to compare the diagnostic value of multi-slice spiral computed tomography (CT) and secretary phospholipase A2-IIa (sPLA2-IIa) in differentiating between malignant and benign solitary pulmonary nodules (SPNs). METHODS: A total of 223 patients with SPNs (91 patients with malignant SPNs and 132 patients with benign SPNs) were included from Weihai Central Hospital during October 2014 to December 2016. SPN diagnosis was confirmed in all patients using needle biopsy, surgery and bronchoscopy...
May 11, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28488310/use-of-tbag-pha-ratio-in-distinguishing-tuberculoma-from-cancer-in-solitary-pulmonary-nodule-or-mass
#3
Feng Wang, Hongyan Hou, Hongmin Zhou, Shiji Wu, Lie Mao, Min Huang, Botao Yin, Jing Huang, Ziyong Sun
INTRODUCTION: Differentiation of tuberculoma from cancer in solitary pulmonary nodule or mass still remains a major challenge in diagnostic laboratories. OBJECTIVES: The objective of this study is to determine the performance of T-SPOT.TB assay in discriminating these two diseases. METHODS: We prospectively enrolled 331 patients with a solitary pulmonary nodule or mass on CT scans. Conventional tests and T-SPOT.TB assay were simultaneously performed in all participants...
May 9, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28463856/multiple-pulmonary-nodules-in-malignancy
#4
Apurwa Karki, Rakesh Shah, Alan Fein
PURPOSE OF REVIEW: Multiple pulmonary nodules are a common finding especially with the implementation of lung cancer screening. Available guidelines address the management of solitary pulmonary nodules. The management of the multiple pulmonary nodules would differ based on the characteristic of the nodules, their distribution, and the history of the patients as well. RECENT FINDINGS: Most of the recent publications on multiple pulmonary nodules consist of individual case reports or case series...
May 1, 2017: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/28451022/-pleuropulmonary-metastases-originating-from-extra-thoracic-neoplasia
#5
Farid Badri, Salma Ait Batahar, Safae El Idrissi, Hafsa Sajiai, Hind Serhane, Lamyae Amro
The lungs receive the entire venous drainage of the body. This explains the high incidence of pleuropulmonary metastases originating from several cancers. The goal of this is to study the clinical manifestations of pleuro-pulmonary metastases originating from extra-thoracic cancers. We conducted a retrospective study of patients with pleuro-pulmonary metastasis whose data were collected in our department between January 2006 and december 2014. 76 patient medical records were studied. The average age was 50 years (aged 21-89 years) with a male predominance in 57...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28423576/solitary-ground-glass-opacity-nodules-of-stage-ia-pulmonary-adenocarcinoma-combination-of-18f-fdg-pet-ct-and-high-resolution-computed-tomography-features-to-predict-invasive-adenocarcinoma
#6
Jun Zhou, Yanli Li, Yiqiu Zhang, Guobing Liu, Hui Tan, Yan Hu, Jie Xiao, Hongcheng Shi
To investigate the performance of combined 18F-FDG Positron Emission Tomography/Computed Tomography with high-resolution CT for differentiating invasive adenocarcinoma from adenocarcinoma in situ (pre-invasive lesion) or minimally invasive adenocarcinoma in stage IA lung cancer patients with solitary ground-glass opacity nodules. This retrospective study enrolled 58 consecutive stage IA pulmonary adenocarcinoma patients with solitary ground-glass opacity nodules. The characteristics and measurements of the ground-glass opacity nodules as pure ground-glass opacity nodules and mixed ground-glass opacity nodules in the pre-invasive or minimally invasive adenocarcinoma and invasive adenocarcinoma groups on Positron Emission Tomography/Computed Tomography and high-resolution CT were compared and analyzed...
April 4, 2017: Oncotarget
https://www.readbyqxmd.com/read/28423346/endobronchial-ultrasound-transbronchial-biopsy-with-guide-sheath-for-the-diagnosis-of-solitary-pulmonary-nodules
#7
Chun-Hua Xu, Qi Yuan, Li-Ke Yu, Wei Wang, Yong Lin
The aim of this study was to assess the usefulness of endobronchial ultrasound transbronchial biopsy with guide-sheath (EBUS-GS-TBB) for the diagnosis of solitary pulmonary nodules (SPNs). One hundred and eighty patients, who were diagnosed with SPNs and underwent an endobronchial ultrasound procedure. The diagnostic yield, safety and the associated factors were analyzed. Mean EBUS-GS procedure time was 14±8 min. The average number of biopsy specimens obtained in each SPNs was 5±1.2. One hundred and thirty-four SPNs were diagnosed by EBUS-GS-TBB and the diagnostic rate was 74...
April 4, 2017: Oncotarget
https://www.readbyqxmd.com/read/28409370/a-plea-for-thoracoscopic-resection-of-solitary-pulmonary-nodule-in-cancer-patients
#8
Jocelyn Bellier, Jean Yannis Perentes, Etienne Abdelnour-Berchtold, Benjamin Lopez, Thorsten Krueger, Catherine Beigelman-Aubry, Hans-Beat Ris, Michel Gonzalez
BACKGROUND: Solitary pulmonary nodules (SPN) are frequently detected in cancer patients. These lesions are often considered as pulmonary metastases and increasingly treated by non-surgical techniques without histological confirmation. The aim of this study is to determine the histological nature of SPN resected by thoracoscopy and to identify risk factors of malignancy. METHODS: Single-institution retrospective analysis of all consecutive patients with previously known malignancies who underwent thoracoscopic resection of SPN with unknown diagnosis between 2001 and 2014...
April 13, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28404977/assessment-of-the-cancer-risk-factors-of-solitary-pulmonary-nodules
#9
Li Yang, Qiao Zhang, Li Bai, Ting-Yuan Li, Chuang He, Qian-Li Ma, Liang-Shan Li, Xue-Quan Huang, Gui-Sheng Qian
There are no large samples or exact prediction models for assessing the cancer risk factors of solitary pulmonary nodules (SPNs) in the Chinese population. We retrospectively analyzed the clinical and imaging data of patients with SPNs who underwent computer tomography guided needle biopsy in our hospital from Jan 1st of 2011 to March 30th of 2016. These patients were divided into a development data set and a validation data set. These groups included 1078 and 344 patients, respectively. A prediction model was developed from the development data set and was validated with the validation data set using logistic regression...
April 25, 2017: Oncotarget
https://www.readbyqxmd.com/read/28386192/study-of-lung-cancer-regulatory-network-that-involves-erbb4-and-tumor-marker-gene
#10
Xuhui Ma, Lu Li, Tongde Tian, Huaimin Liu, Qiujian Li, Qilong Gao
Our purpose is to screen out serum tumor markers closely correlated to the nature of solitary pulmonary nodule (SPN) and to draw a regulatory network containing genes correlated to lung cancer. Two hundred and sixty cases of SPN patients confirmed through pathological diagnosis were collected as subjects, factors closely correlated to the nature of SPN were screened out from eight tumor markers through Fisher discriminant method, and functional annotation and pathway analysis were conducted on erbB4 as well as its tumor marker genes by GO and KEGG databases...
March 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28377340/-combined-use-of-thin-section-ct-and-18-f-fdg-pet-ct-for-characterization-of-solitary-pulmonary-nodules
#11
Yun-Yan Ren, You-Cai Li, Hu-Bing Wu, Quan-Shi Wang, Yan-Jiang Han, Wen-Lan Zhou, Hong-Sheng Li, Zhen Wang, Mohammed Shah Alam Mohammed Shah Alam
OBJECTIVE: To investigate whether fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) combined with thin-section CT improves the diagnostic performance for solitary pulmonary nodules (SPNs). METHODS: A total of 267 patients underwent examinations with (18)F-FDG PET/CT and thin-section CT for evaluating the SPNs with undetermined nature, which was further confirmed by pathological examination or clinical follow-up. The performance of two diagnostic criteria based on findings in PET/CT alone (Criterion 1) and in PET/CT combined with thin-section CT (Criterion 2) were compared...
March 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28361002/a-case-of-lung-abscess-successfully-treated-by-transbronchial-drainage-using-a-guide-sheath
#12
Hiroki Izumi, Masahiro Kodani, Shingo Matsumoto, Yuji Kawasaki, Tadashi Igishi, Eiji Shimizu
A 51-year-old man was diagnosed with colon cancer in September 2011, and a solitary pulmonary nodule was detected by computed tomography (CT) scan. We performed a transbronchial biopsy with endobronchial ultrasonography using a guide sheath (GS) and diagnosed lung metastasis of colon cancer. The patient experienced remittent fever after the biopsy in spite of intravenous antibiotic therapies. Moreover, his CT scan showed a large lung abscess at the biopsy site. We performed transbronchial drainage using a GS as salvage therapy...
May 2017: Respirology Case Reports
https://www.readbyqxmd.com/read/28331827/transthoracic-needle-aspiration-in-solitary-pulmonary-nodule
#13
REVIEW
Wen Yang, Hongli Jiang, Ali Nawaz Khan, Carolyn Allen, Luca Bertolaccini, Tangfeng Lv, Yong Song
With improved awareness of public health and the recent advances in various imaging technologies, the detection rate of solitary pulmonary nodules (SPN) is continuously increasing. Transthoracic needle aspiration (TTNA) has represented a major approach for the diagnosis and differential diagnosis of pulmonary masses, owing to its simplicity and minimal invasiveness. This paper demonstrates the role of TTNA in SPN.
February 2017: Translational Lung Cancer Research
https://www.readbyqxmd.com/read/28301552/radiological-characteristics-of-pulmonary-cryptococcosis-in-hiv-infected-patients
#14
Zhiliang Hu, Jun Chen, Juan Wang, Qingfang Xiong, Yandan Zhong, Yongfeng Yang, Chuanjun Xu, Hongxia Wei
BACKGROUND: Current understanding of human immunodeficiency virus (HIV)-associated pulmonary cryptococcosis (PC) is largely based on studies performed about 2 decades ago which reported that the most common findings on chest radiograph were diffuse interstitial infiltrates. Few studies are available regarding the computed tomography (CT) findings. The aim of this study was to characterize chest CT features of HIV-associated PC. METHODS: HIV patients with cryptococccal infection and pulmonary abnormalities on Chest CT between September 2010 and May 2016 in the Second Affiliated Hospital of the Southeast University were retrospectively analyzed...
2017: PloS One
https://www.readbyqxmd.com/read/28250863/primary-pulmonary-lymphoepithelioma-like-carcinoma-on-fdg-pet-ct
#15
Gul Ege Aktas, Nuray Can, Selin Soyluoglu Demir, Ali Sarıkaya
A 69-year-old male smoker was referred to (18)F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET/CT) with the indication of a suspicious solitary pulmonary nodule. FDG PET/CT determined a 2.5 × 2-cm soft-tissue lesion (SUVmax, 16.2) with spiculated margins in the hilum of the right lung. A 1-cm diameter lymphadenopathy on the right hilum with an SUVmax of 3.2 was also determined. Transbronchial biopsy of the right hilar lymphadenopathy did not reveal any malignant features in histopathologic examination, and it was determined to be reactive...
March 2017: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28219077/radiopathological-features-and-identification-of-mycobacterial-infections-in-granulomatous-nodules-resected-from-the-lung
#16
Yumi Sakakibara, Yoshimi Suzuki, Toshihide Fujie, Takumi Akashi, Tadatsune Iida, Yasunari Miyazaki, Yoshinobu Eishi, Naohiko Inase
BACKGROUND: Pulmonary granulomas are sometimes resected because they resemble lung cancer and false-positive findings come through from positron emission tomography (PET) using 18fluorine-fluorodeoxyglucose (18F-FDG). Mycobacterial infection is a common cause of granulomas. OBJECTIVE: The purpose of this study was to evaluate the radiopathological features and the methods for identifying mycobacterial infections in granulomatous nodules resected from the lung. METHODS: Thirty-five solitary lesions resected because of suspected lung cancer were enrolled, including 22 nonfungal granulomatous lesions and 13 benign lesions as controls...
2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28195907/solitary-psma-positive-pulmonary-metastasis-in-biochemical-relapse-of-prostate-cancer
#17
Nils Groe Hokamp, Carsten Kobe, Eric Linzenich, David Maintz, Alexander Drzezga
A 63-year-old man with a history of prostate cancer, treated with resection, radiation, and androgen-depriving therapy over 4 years, was referred to our department with suspicion of recurrence based on increased blood PSA levels (1.60 ng/mL). Ga PSMA PET/CT identified a solitary, PSMA-positive pulmonary nodule in the right lung. After resection, histologic analysis confirmed prostatic origin, and the blood PSA level decreased to 0.13 ng/mL. Solitary pulmonary metastasis from prostate cancer is rare. The benefits of local treatment of a single metastasis even in advanced disease are disputed among oncologists...
May 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28180106/primary-intrapulmonary-thymoma-presenting-as-a-solitary-pulmonary-nodule
#18
Woohyun Jung, Chang Hyun Kang, Young Tae Kim, In Kyu Park
Primary intrapulmonary thymoma (PIT) is a very rare lesion of uncertain pathogenesis. PIT should be considered when the histopathological appearance of a lung tumor shows features that are uncommon but similar to those of a thymoma. In this case report, we discuss the case of a 59-year-old female with a solitary pulmonary nodule that was confirmed to be PIT on the basis of pathological tests. Treatment with complete resection showed good results.
February 2017: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28159371/challenges-in-interpretation-of-staging-pet-ct-in-thoracic-malignancies
#19
REVIEW
Girish S Shroff, Brett W Carter, Chitra Viswanathan, Marcelo F Benveniste, Carol C Wu, Edith M Marom, Osama R Mawlawi, Mylene T Truong
(18)F-fluorodeoxryglucose ((18)F-FDG) PET/CT imaging is routinely performed in the evaluation of patients with known or suspected thoracic malignancy. Indications for its use include staging of malignancy, assessment of response to therapy, evaluation of suspected disease recurrence, and evaluation of a solitary pulmonary nodule. In this article, we will discuss specific technical artifacts and also review potential pitfalls in the interpretation of PET/CT in thoracic malignancies including normal variations in physiologic uptake of FDG, benign conditions (such as infection, inflammation, posttreatment changes, and iatrogenic factors) that can result in increased FDG uptake, and malignancies that demonstrate scarce to no FDG uptake...
December 6, 2016: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28148271/surgical-treatment-in-non-small-cell-lung-cancer-with-pulmonary-oligometastasis
#20
Jinyuan He, Yun Li, Jun An, Liu Hu, Junhang Zhang
BACKGROUND: Previous studies have demonstrated survival benefits for local treatment in solitary metastatic non-small cell lung cancer (NSCLC).This study aimed to investigate the effect of local surgery for NSCLC with pulmonary oligometastasis. METHODS: This study included 21 patients of NSCLC with pulmonary oligometastasis between January 2003 and December 2013, which were divided into two groups, group A (11 cases) for local surgery and group B (10 cases) for systematic chemotherapy, compared the median survival time (MST) and 5-year survival rate between the two groups, and analyzed the impact of the pathological types, the TNM and pN stage of primary tumor, the site, and the mode and number of oligometastatic nodule on group A...
February 2, 2017: World Journal of Surgical Oncology
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