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Thomas L Spray

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https://www.readbyqxmd.com/read/28091570/increasing-the-potential-for-malaria-elimination-by-targeting-zoophilic-vectors
#1
Jessica L Waite, Sunita Swain, Penelope A Lynch, S K Sharma, Mohammed Asrarul Haque, Jacqui Montgomery, Matthew B Thomas
Countries in the Asia Pacific region aim to eliminate malaria by 2030. A cornerstone of malaria elimination is the effective management of Anopheles mosquito vectors. Current control tools such as insecticide treated nets or indoor residual sprays target mosquitoes in human dwellings. We find in a high transmission region in India, malaria vector populations show a high propensity to feed on livestock (cattle) and rest in outdoor structures such as cattle shelters. We also find evidence for a shift in vector species complex towards increased zoophilic behavior in recent years...
January 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28031423/neurologic-injury-and-cerebral-blood-flow-in-single-ventricles-throughout-staged-surgical-reconstruction
#2
Mark A Fogel, Christine J Li, Okan U Elci, Tom Pawlowski, Peter J Schwab, Felice B Wilson, Susan C Nicolson, Lisa M Montenegro, Laura Diaz, Thomas L Spray, J William Gaynor, Stephanie Fuller, Christopher E Mascio, Marc S Keller, Matthew A Harris, Kevin K Whitehead, James Bethel, Arastoo Vossough, Daniel J Licht
BACKGROUND: -Single ventricle patients experience a high rate of brain injury and adverse neurodevelopmental outcome, however, the incidence of brain abnormalities throughout surgical reconstruction and its relationship with cerebral blood flow, oxygen delivery and carbon dioxide reactivity remains unknown. METHODS: -Single ventricle patients were studied with MRI scans immediately prior to bidirectional Glenn (pre-BDG), prior to Fontan and then 3-9 months after Fontan reconstruction...
December 28, 2016: Circulation
https://www.readbyqxmd.com/read/28012848/detection-of-sessile-serrated-adenomas-in-proximal-colon-using-wide-field-fluorescence-endoscopy
#3
Bishnu P Joshi, Zhenzhen Dai, Zhenghong Gao, Jeong Hoon Lee, Navin Ghimire, Jing Chen, Anoop Prabhu, Erik J Wamsteker, Richard S Kwon, Grace H Elta, Elena M Stoffel, Asha Pant, Tonya Kaltenbach, Roy M Soetikno, Henry D Appelman, Rork Kuick, D Kim Turgeon, Thomas D Wang
BACKGROUND & AIMS: Many cancers in the proximal colon develop via from sessile serrated adenomas (SSAs), which have flat, subtle features that are difficult to detect with conventional white-light colonoscopy. Many SSA cells have the V600E mutation in BRAF. We investigated whether this feature could be used with imaging methods to detect SSAs in patients. METHODS: We used phage display to identify a peptide that binds specifically to SSAs, using subtractive hybridization with HT29 colorectal cancer cells containing the V600E mutation in BRAF and Hs738...
December 21, 2016: Gastroenterology
https://www.readbyqxmd.com/read/28007065/a-word-of-caution-in-public-reporting
#4
REVIEW
Thomas L Spray, J William Gaynor
Public reporting in its current form will lead to confusion amongst physicians, administrators, families, and the media. It is unclear that we are giving the families information they really need. At the current time there is no evidence that public reporting really leads to improved outcomes. Rather, it may lead to risk aversion and limit access to care. This is a problem not just for congenital heart surgery but for the entire field of medicine and the care that we provide to our patients. We must be very careful that we don't create a system where we are afraid to take on a patient with increased risk of mortality because it may affect our overall ranking...
January 2017: Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual
https://www.readbyqxmd.com/read/27919455/potential-benefits-and-consequences-of-public-reporting-of-pediatric-cardiac-surgery-outcomes
#5
EDITORIAL
J William Gaynor, Sara K Pasquali, Richard G Ohye, Thomas L Spray
No abstract text is available yet for this article.
October 28, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27834765/a-comparison-of-perioperative-management-of-anomalous-aortic-origin-of-a-coronary-artery-between-an-adult-and-pediatric-cardiac-center
#6
Jeremy L Herrmann, Leah A Goldberg, Abigail M Khan, Sara L Partington, Julie A Brothers, Christopher E Mascio, Thomas L Spray, Yuli Y Kim, Stephanie Fuller
BACKGROUND: Anomalous aortic origin of a coronary artery (AAOCA) presents in varying age-groups. Assuming management algorithms differ between pediatric and adult institutions, we compared the perioperative management of patients with AAOCA at two such centers. METHODS: A retrospective review was conducted at a pediatric and an adult institution of patients 14 years or older who underwent surgical repair of AAOCA between January 2000 and May 2014. RESULTS: Twenty patients from the pediatric center (median age: 16...
November 2016: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/27769563/comparison-of-a-novel-porous-titanium-construct-regenerex%C3%A2-to-a-well-proven-porous-coated-tibial-surface-in-cementless-total-knee-arthroplasty-a-prospective-randomized-rsa-study-with-two-year-follow-up
#7
Nikolaj S Winther, Claus L Jensen, Claus M Jensen, Thomas Lind, Henrik M Schrøder, Gunnar Flivik, Michael M Petersen
BACKGROUND: Regenerex is a novel porous titanium construct with a three-dimensional porous structure and biomechanical characteristics close to that of normal trabecular bone. The aim of this study was to compare this novel construct to a well-proven porous plasma sprayed tibial (PPS) implant after total knee arthroplasty. METHODS: Sixty-one patients scheduled for an uncemented TKA were randomized to receive either a novel highly porous titanium construct Regenerex or the PPS tibial component...
December 2016: Knee
https://www.readbyqxmd.com/read/27688219/strengthening-health-systems-while-responding-to-a-health-crisis-lessons-learned-by-a-nongovernmental-organization-during-the-ebola-virus-disease-epidemic-in-sierra-leone
#8
Corrado Cancedda, Sheila M Davis, Kerry L Dierberg, Jonathan Lascher, J Daniel Kelly, Mohammed Bailor Barrie, Alimamy Philip Koroma, Peter George, Adikali Alpha Kamara, Ronald Marsh, Manso S Sumbuya, Cameron T Nutt, Kirstin W Scott, Edgar Thomas, Katherine Bollbach, Andrew Sesay, Ahmidu Barrie, Elizabeth Barrera, Kathryn Barron, John Welch, Nahid Bhadelia, Raphael G Frankfurter, Ophelia M Dahl, Sarthak Das, Rebecca E Rollins, Bryan Eustis, Amanda Schwartz, Piero Pertile, Ilias Pavlopoulos, Allan Mayfield, Regan H Marsh, Yusupha Dibba, Danielle Kloepper, Andrew Hall, Karin Huster, Michael Grady, Kimberly Spray, David A Walton, Fodei Daboh, Cora Nally, Sahr James, Gabriel S Warren, Joyce Chang, Michael Drasher, Gina Lamin, Sherry Bangura, Ann C Miller, Annie P Michaelis, Ryan McBain, M Jana Broadhurst, Megan Murray, Eugene T Richardson, Ted Philip, Gary L Gottlieb, Joia S Mukherjee, Paul E Farmer
An epidemic of Ebola virus disease (EVD) beginning in 2013 has claimed an estimated 11 310 lives in West Africa. As the EVD epidemic subsides, it is important for all who participated in the emergency Ebola response to reflect on strengths and weaknesses of the response. Such reflections should take into account perspectives not usually included in peer-reviewed publications and after-action reports, including those from the public sector, nongovernmental organizations (NGOs), survivors of Ebola, and Ebola-affected households and communities...
October 15, 2016: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27668731/reducing-the-use-of-pesticides-with-site-specific-application-the-chemical-control-of-rhizoctonia-solani-as-a-case-of-study-for-the-management-of-soil-borne-diseases
#9
Ronan Le Cointe, Thomas E Simon, Patrick Delarue, Maxime Hervé, Melen Leclerc, Sylvain Poggi
Reducing our reliance on pesticides is an essential step towards the sustainability of agricultural production. One approach involves the rational use of pesticides combined with innovative crop management. Most control strategies currently focus on the temporal aspect of epidemics, e.g. determining the optimal date for spraying, regardless of the spatial mechanics and ecology of disease spread. Designing innovative pest management strategies incorporating the spatial aspect of epidemics involves thorough knowledge on how disease control affects the life-history traits of the pathogen...
2016: PloS One
https://www.readbyqxmd.com/read/27590602/eave-tubes-for-malaria-control-in-africa-a-modelling-assessment-of-potential-impact-on-transmission
#10
Jessica L Waite, Penelope A Lynch, Matthew B Thomas
BACKGROUND: Novel interventions for malaria control are necessary in the face of problems such as increasing insecticide resistance and residual malaria transmission. One way to assess performance prior to deployment in the field is through mathematical modelling. Modelled here are a range of potential outcomes for eave tubes, a novel mosquito control tool combining house screening and targeted use of insecticides to provide both physical protection and turn the house into a lethal mosquito killing device...
2016: Malaria Journal
https://www.readbyqxmd.com/read/27529118/leaching-of-the-neonicotinoids-thiamethoxam-and-imidacloprid-from-sugar-beet-seed-dressings-to-subsurface-tile-drains
#11
Felix E Wettstein, Roy Kasteel, Maria F Garcia Delgado, Irene Hanke, Sebastian Huntscha, Marianne E Balmer, Thomas Poiger, Thomas D Bucheli
Pesticide transport from seed dressings toward subsurface tile drains is still poorly understood. We monitored the neonicotinoid insecticides imidacloprid and thiamethoxam from sugar beet seed dressings in flow-proportional drainage water samples, together with spray applications of bromide and the herbicide S-metolachlor in spring and the fungicides epoxiconazole and kresoxim-methyl in summer. Event-driven, high first concentration maxima up to 2830 and 1290 ng/L for thiamethoxam and imidacloprid, respectively, were followed by an extended period of tailing and suggested preferential flow...
August 24, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27515306/eave-tubes-for-malaria-control-in-africa-an-introduction
#12
Bart G J Knols, Marit Farenhorst, Rob Andriessen, Janneke Snetselaar, Remco A Suer, Anne J Osinga, Johan M H Knols, Johan Deschietere, Kija R Ng'habi, Issa N Lyimo, Stella T Kessy, Valeriana S Mayagaya, Sergej Sperling, Michael Cordel, Eleanore D Sternberg, Patrick Hartmann, Ladslaus L Mnyone, Andreas Rose, Matthew B Thomas
In spite of massive progress in the control of African malaria since the turn of the century, there is a clear and recognized need for additional tools beyond long-lasting insecticide-treated bed nets (LLINs) and indoor residual spraying (IRS) of insecticides, to progress towards elimination. Moreover, widespread and intensifying insecticide resistance requires alternative control agents and delivery systems to enable development of effective insecticide resistance management strategies. This series of articles presents a novel concept for malaria vector control, the 'eave tube', which may fulfil these important criteria...
2016: Malaria Journal
https://www.readbyqxmd.com/read/27449354/historical-perspectives-of-the-american-association-for-thoracic-surgery-thomas-l-spray
#13
EDITORIAL
James S Tweddell
No abstract text is available yet for this article.
October 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27259164/iodide-residues-in-milk-vary-between-iodine-based-teat-disinfectants
#14
Elizabeth A French, Motoko Mukai, Michael Zurakowski, Bradley Rauch, Gloria Gioia, Joseph R Hillebrandt, Mark Henderson, Ynte H Schukken, Thomas C Hemling
Majority of iodine found in dairy milk comes from the diet and teat disinfection products used during milking process. The objective of this study was to evaluate the effects of 4 iodine-based teat dips on milk iodide concentrations varying in iodine level (0.25% vs. 0.5%, w/w), normal low viscosity dip versus barrier dip, and application method (dip vs. spray) to ensure safe iodine levels in dairy milk when these products are used. The iodine exposure study was performed during a 2-wk period. The trial farm was purged of all iodine-based disinfection products for 21 d during a prestudy "washout period," which resulted in baseline milk iodide range of 145 to 182 ppb...
July 2016: Journal of Food Science
https://www.readbyqxmd.com/read/27208757/manganese-concentrations-in-drinking-water-from-villages-near-banana-plantations-with-aerial-mancozeb-spraying-in-costa-rica-results-from-the-infants-environmental-health-study-isa
#15
Berna van Wendel de Joode, Benoit Barbeau, Maryse F Bouchard, Ana María Mora, Åsa Skytt, Leonel Córdoba, Rosario Quesada, Thomas Lundh, Christian H Lindh, Donna Mergler
Elevated manganese (Mn) in drinking water has been reported worldwide. While, naturally occurring Mn in groundwater is generally the major source, anthropogenic contamination by Mn-containing fungicides such as mancozeb may also occur. The main objective of this study was to examine factors associated with Mn and ethylenethiourea (ETU), a degradation product of mancozeb, in drinking water samples from villages situated near banana plantations with aerial spraying of mancozeb. Drinking water samples (n = 126) were obtained from 124 homes of women participating in the Infants' Environmental Health Study (ISA, for its acronym in Spanish), living nearby large-scale banana plantations...
August 2016: Environmental Pollution
https://www.readbyqxmd.com/read/27183886/increasing-cumulative-exposure-to-volatile-anesthetic-agents-is-associated-with-poorer-neurodevelopmental-outcomes-in-children-with-hypoplastic-left-heart-syndrome
#16
Laura K Diaz, J William Gaynor, Shannon J Koh, Richard F Ittenbach, Marsha Gerdes, Judy C Bernbaum, Elaine H Zackai, Robert R Clancy, Mohamed A Rehman, Jeffrey W Pennington, Nancy Burnham, Thomas L Spray, Susan C Nicolson
OBJECTIVES: Despite improved survival in children with hypoplastic left heart syndrome (HLHS), significant concern persists regarding their neurodevelopmental (ND) outcomes. Previous studies have identified patient factors, such as prematurity and genetic syndromes, to be associated with worse ND outcomes. However, no consistent relationships have been identified among modifiable management factors, including cardiopulmonary bypass strategies, and ND outcomes after cardiac surgery in infancy...
August 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27162962/microbial-control-of-sea-spray-aerosol-composition-a-tale-of-two-blooms
#17
Xiaofei Wang, Camille M Sultana, Jonathan Trueblood, Thomas C J Hill, Francesca Malfatti, Christopher Lee, Olga Laskina, Kathryn A Moore, Charlotte M Beall, Christina S McCluskey, Gavin C Cornwell, Yanyan Zhou, Joshua L Cox, Matthew A Pendergraft, Mitchell V Santander, Timothy H Bertram, Christopher D Cappa, Farooq Azam, Paul J DeMott, Vicki H Grassian, Kimberly A Prather
With the oceans covering 71% of the Earth, sea spray aerosol (SSA) particles profoundly impact climate through their ability to scatter solar radiation and serve as seeds for cloud formation. The climate properties can change when sea salt particles become mixed with insoluble organic material formed in ocean regions with phytoplankton blooms. Currently, the extent to which SSA chemical composition and climate properties are altered by biological processes in the ocean is uncertain. To better understand the factors controlling SSA composition, we carried out a mesocosm study in an isolated ocean-atmosphere facility containing 3,400 gallons of natural seawater...
June 24, 2015: ACS Central Science
https://www.readbyqxmd.com/read/27149205/update-ongoing-zika-virus-transmission-puerto-rico-november-1-2015-april-14-2016
#18
Emilio Dirlikov, Kyle R Ryff, Jomil Torres-Aponte, Dana L Thomas, Janice Perez-Padilla, Jorge Munoz-Jordan, Elba V Caraballo, Myriam Garcia, Marangely Olivero Segarra, Graciela Malave, Regina M Simeone, Carrie K Shapiro-Mendoza, Lourdes Romero Reyes, Francisco Alvarado-Ramy, Angela F Harris, Aidsa Rivera, Chelsea G Major, Marrielle Mayshack, Luisa I Alvarado, Audrey Lenhart, Miguel Valencia-Prado, Steve Waterman, Tyler M Sharp, Brenda Rivera-Garcia
Zika virus is a flavivirus transmitted primarily by Aedes species mosquitoes, and symptoms of infection can include rash, fever, arthralgia, and conjunctivitis (1).* Zika virus infection during pregnancy is a cause of microcephaly and other severe brain defects (2). Infection has also been associated with Guillain-Barré syndrome (3). In December 2015, Puerto Rico became the first U.S. jurisdiction to report local transmission of Zika virus, with the index patient reporting symptom onset on November 23, 2015 (4)...
May 6, 2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27134806/mineralogy-provenance-and-diagenesis-of-a-potassic-basaltic-sandstone-on-mars-chemin-x-ray-diffraction-of-the-windjana-sample-kimberley-area-gale-crater
#19
Allan H Treiman, David L Bish, David T Vaniman, Steve J Chipera, David F Blake, Doug W Ming, Richard V Morris, Thomas F Bristow, Shaunna M Morrison, Michael B Baker, Elizabeth B Rampe, Robert T Downs, Justin Filiberto, Allen F Glazner, Ralf Gellert, Lucy M Thompson, Mariek E Schmidt, Laetitia Le Deit, Roger C Wiens, Amy C McAdam, Cherie N Achilles, Kenneth S Edgett, Jack D Farmer, Kim V Fendrich, John P Grotzinger, Sanjeev Gupta, John Michael Morookian, Megan E Newcombe, Melissa S Rice, John G Spray, Edward M Stolper, Dawn Y Sumner, Ashwin R Vasavada, Albert S Yen
The Windjana drill sample, a sandstone of the Dillinger member (Kimberley formation, Gale Crater, Mars), was analyzed by CheMin X-ray diffraction (XRD) in the MSL Curiosity rover. From Rietveld refinements of its XRD pattern, Windjana contains the following: sanidine (21% weight, ~Or95); augite (20%); magnetite (12%); pigeonite; olivine; plagioclase; amorphous and smectitic material (~25%); and percent levels of others including ilmenite, fluorapatite, and bassanite. From mass balance on the Alpha Proton X-ray Spectrometer (APXS) chemical analysis, the amorphous material is Fe rich with nearly no other cations-like ferrihydrite...
January 2016: Journal of Geophysical Research. Planets
https://www.readbyqxmd.com/read/27132984/applying-surface-energy-derived-cohesive-adhesive-balance-model-in-predicting-the-mixing-flow-and-compaction-behaviour-of-interactive-mixtures
#20
Sharad Mangal, Felix Meiser, Geoffrey Tan, Thomas Gengenbach, David A V Morton, Ian Larson
OBJECTIVE: In this study, we investigated the applicability of cohesive-adhesive balance (CAB) model to predict the interactive mixing behaviour of small excipient particles. Further, we also investigated the application of this CAB model to predict the flow and compactibility of resultant blends. METHODS: Excipients created by co-spraying polyvinylpyrrolidone (PVP, a model pharmaceutical binder) with various l-leucine concentrations were used for this study. Paracetamol was used as model active pharmaceutical ingredient (API)...
July 2016: European Journal of Pharmaceutics and Biopharmaceutics
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