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Yun-Wei Guo, Hui-Biao Miao, Zhuo-Fu Wen, Jie-Ying Xuan, Hao-Xiong Zhou
AIM: To focus on procedure-related complications, evaluate their incidence, analyze the reasons and discuss the solutions. METHODS: Overall, 628 endoscopic gastric variceal obturation (EGVO) procedures (case-times) with NBC were performed in 519 patients in the Department of Endoscopy of the Third Affiliated Hospital of Sun Yat-Sen University from January 2011 to December 2016. The clinical data of patients and procedure-related complications of EGVO were retrospectively analyzed...
November 21, 2017: World Journal of Gastroenterology: WJG
Christopher Fenelon, John G Galbraith, Paul Hession, Lester G D'Souza
Achilles tendinopathy can be a chronic disabling condition affecting both athletic and sedentary patients. Multiple new treatment approaches have developed, including shock wave therapy and various types of injection. One of the novel treatment methods used is the injection of Aethoxysklerol or polidocanol, a sclerosing substance injected under ultrasound guidance targeting areas of neovascularisation. We report the case of a 78-year-old lady who suffered a complete Achilles tendon rupture following injection of Aethoxysklerol...
December 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
D J B Keene, R M Cervellione
INTRODUCTION: In the 1970s, Tauber described the antegrade sclerotherapy technique to treat varicoceles, and reported a 10% recurrence rate. The present study aimed to evaluate paediatric success rates and the effect of modifications to the surgical technique. METHODS: A prospective study was performed of all adolescent patients undergoing antegrade sclerotherapy surgery. Each patient had an idiopathic varicocele with spontaneous venous reflux on Doppler examination, and underwent cannulation of a pampiniform plexus vein via a scrotal incision under general anaesthetic...
January 29, 2017: Journal of Pediatric Urology
Resmije Ademi Abdyli, Yll Abdyli, Feriall Perjuci, Ali Gashi, Zana Agani, Jehona Ahmedi
Hemangioma is the clinical term for a benign vascular neoplasm due to proliferation of the endothelial lining of blood vessels. Their most frequent location is the body skin and oral mucosa. One of the treatment modalities for hemangiomas is intralesional injection of sclerosing agents which cause the damage of blood vessels followed by their obliteration. The objective of the study was to describe the facility of application and evaluate the efficiency of sclerotherapy with aethoxysklerol 1%. Method. The case presented with intraoral submucosal hemangioma of the cheek was treated by intralesional injection of aethoxysklerol 3% diluted in water for injections at a 4 : 1 ratio (0...
2016: Case Reports in Dentistry
Jacek Kurnicki, Marcin Osęka, Robert Tworus, Zbigniew Gałązka
INTRODUCTION: Ultrasound-guided foam sclerotherapy (UGFS) of varicose veins is a useful treatment option. It is a relatively safe method in the case of limited, small varicose veins. In theory, a justified concern could be raised that the injection of an active drug into the large superficial venous vessels may potentially cause life-threatening consequences. AIM: To assess the safety and efficacy of UGFS using a 2% solution of polidocanol (Aethoxysklerol 2%) in the case of great saphenous vein incompetence...
2016: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
Bibombe P Mwipatayi, Catherine E Western, Jackie Wong, Donna Angel
INTRODUCTION: Skin necrosis is a rare complication of foam sclerotherapy, a common form of treatment for varicose veins. PRESENTATION OF CASE: Both patients presented to the outpatient clinic within 2-14days after foam sclerotherapy with Aethoxysklerol(®) 1%, with severe soft tissue and skin necrosis. Further aggressive treatment of the ulcer was required to resolve the necrosis, resulting in marked residual scar and well granulated leg ulcer respectively. DISCUSSION: Foam sclerotherapy is a common and usually well-tolerated treatment modality for varicose veins...
2016: International Journal of Surgery Case Reports
Gülsüm Tetik Menevşe, Ali TeomanTellioglu, Nurgül Altuntas, Ayhan Cömert, Ibrahim Tekdemir
BACKGROUND AND AIM: Surgical delay is an invasive method requiring a two-stage surgical procedure. Hence, methods that may serve as an alternative to surgical delay have become the focus of interest of research studies. From a conceptual view, any technique that interrupts the blood flow along the edges of a proposed flap will render the flap ischemic and induce a delay phenomenon. Polidocanol (Aethoxysklerol(®)-Kreussler) was initially used as a local anesthetic. Nowadays, it has been used as a sclerosing agent to treat telangiectasias and varicose veins...
June 2014: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
Darío Morais, Teresa Millás, Roberto Zarrabeitia, Luisa M Botella, Ana Almaraz
Hereditary Haemorrhagic Telangiectasia or Rendu-Osler-Weber syndrome is a rare autosomal dominant vascular disease characterized by mucocutaneous and gastrointestinal telangiectases and localized arteriovenous malformations in lung, brain and liver. Epistaxis, due to rupture of telangiectases of the nasal mucosa, is the most frequent clinical manifestation, leading in many cases to severe impairment of the quality of life in the patients. Though several treatments have been used to reduce epistaxis, none have been completely effective, with the exception of polydocanol (Aethoxysklerol®) in submucosal or subpericondrial injections, which was first presented in 2000 with very good results...
March 2012: Rhinology
Jane Ashley Stuckey, William W Miller, Gregory T Almond
A case of a salivary gland mucocele in a dog causing nonpainful exopthalmos with dorsolateral deviation of the globe and protrusion of the third eyelid. Diagnosis was made via ultrasound and confirmed with computed tomography. Aspiration of the cystic material along with injection of a sclerosing agent, 1% polidocanol (Aethoxysklerol), was used to destroy the mucocele. Follow-up monthly examination post injection confirmed resolution of clinical signs to date, namely abnormal globe position, with no complications observed...
May 2012: Veterinary Ophthalmology
J Zhang, Z Jing, D E Schliephake, J Otto, G M Malouf, Y-Q Gu
OBJECTIVES: To assess efficacy and safety of polidocanol (POL) versus placebo in the treatment of C1 and C2 non-saphenous varicose veins in Chinese patients. METHODS: Patients were randomly assigned to POL or placebo. POL 0.5%, 1% and 3% were administered depending on varicose vein type. Response after 12 weeks was defined as Grade 4 or 5 on a digital imaging-based five-point scale (C1 veins) or occlusion and/or absence of reflux >0.5 second (C2 veins). Safety was evaluated with a five-point scale and standard safety assessments...
June 2012: Phlebology
Kahraman Berkhan Yilmaz, Halil Ibrahim Canter, Ibrahim Vargel, Tugrul Ormeci, Ulas Can, Ali Turk, Ozlem Saygili
Hemangiomas (proliferating endothelial tumors) are the most common benign tumors of infancy. Most often hemangiomas are self-regressing lesions without any treatment. Approximately 10% of hemangiomas cause complications such as major ulceration/destruction, distortion of involved tissues, and obstruction of a vital structure. When the situation becomes complicated, there are different treatment alternatives, ranging from systemic or local corticosteroid use to surgery. Sclerotherapy using intralesional polidocanol (Aethoxysklerol) injection may be used before surgery to decrease blood loss or when a vital structure of the face is in danger because of sudden increase in size of a surrounding hemangioma...
September 2011: Journal of Craniofacial Surgery
Jun Cui, Liu-Ye Huang, Yun-Xiang Liu, Bo Song, Long-Zhi Yi, Ning Xu, Bo Zhang, Cheng-Rong Wu
AIM: To investigate the endoscopic hemostasis for gastrointestinal bleeding due to Dieulafoy's lesion. METHODS: One hundred and seven patients with gastrointestinal bleeding due to Dieulafoy's lesion were treated with three endoscopic hemostasis methods: aethoxysklerol injection (46 cases), endoscopic hemoclip hemostasis (31 cases), and a combination of hemoclip hemostasis with aethoxysklerol injection (30 cases). RESULTS: The rates of successful hemostasis using the three methods were 71...
March 14, 2011: World Journal of Gastroenterology: WJG
Sang-Hoon Chung, Myung-su Lee, Kyung Sik Kim, Soon Ii Kim, Jong Youn Won, Do Yun Lee, Kwang-Hun Lee
PURPOSE: To evaluate the clinical safety and effectiveness of foam sclerotherapy using polidocanol for preoperative portal vein embolization (PVE) before hemihepatectomy of the liver. MATERIALS AND METHODS: From March 2006 to October 2008, foam sclerotherapy using polidocanol was performed in 16 patients (male-to-female ratio of 12:4, age range 48-75 years [mean 62]) for PVE. Patients were diagnosed with Klatskin tumor (n = 13), gallbladder (GB) cancer (n = 2), or hepatocellular carcinoma (HCC) (n = 1)...
December 2011: Cardiovascular and Interventional Radiology
Sun Young Choi, Jong Yun Won, Kyung Ah Kim, Do Yun Lee, Kwang-Hun Lee
PURPOSE: To evaluate the clinical safety and effectiveness of foam sclerotherapy using polidocanol for the treatment of gastric fundal varices by balloon-occluded retrograde transvenous obliteration (BRTO). MATERIALS AND METHODS: From November 2005 to June 2009, foam sclerotherapy using polidocanol for the treatment of gastric fundal varices by BRTO was performed in 16 patients (male/female 11:5; age range 46-84 years, median 67 years). Foam was made of 3% polidocanol (Aethoxysklerol; Kreussler Pharma, Wiesbaden, Germany), room air, and contrast media, with a ratio of 1:2:1, respectively...
January 2011: European Radiology
Stephan Kobus, Stefanie Reich-Schupke, Lukas Pindur, Peter Altmeyer, Markus Stucker
Malignancy increases the risk of thromboembolic events. Vascular events such as venous thromboses can even precede the diagnosis of cancer. A 48-year-old woman presented with an extensive thrombophlebitis of the left small saphenous vein and a perforating vein of the right leg after foam sclerotherapy with Aethoxysklerol foam 0.5% for small varicose veins of both lower legs. A few days later an unknown advanced breast cancer was diagnosed. This case shows that not only venous thromboses but also thrombophlebitis can be a warning sign for malignancy...
March 2009: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
Carlos Bermúdez, Juan Pérez-Wulff, Mauricio Arcadipane, Gesualdo Bufalino, Libardo Gómez, Luis Flores, Cristian Sosa, Patricia W Bornick, Eftichia Kontopoulos, Rubén A Quintero
OBJECTIVES: Congenital cystic adenomatoid malformation (CCAM) is a rare lesion of the developing fetal lung consisting of increased cell proliferation in the bronchial structures with lack of differentiation of the alveoli. Pregnancies may be at an increased risk for perinatal loss with type III CCAM. The purpose of this paper is to present our experience with the management of complicated types II and III CCAM with a novel technique: percutaneous ultrasound-guided fetal sclerotherapy (FST)...
2008: Fetal Diagnosis and Therapy
Bei Shi, Wei Wu, Hui Zhu, Yun-Lin Wu
Two patients with liver cirrhosis and portal hypertension related to hepatitis infection were admitted to Shanghai Ruijin Hospital due to recurrent melena and hematemesis. Isolated gastric varices were observed in the gastric fundus during the retroflexion of gastroscope. We carried out endoscopic sclerotherapy successfully for bleeding gastric varices with combined cyanoacrylate and aethoxysklerol, which disappeared dramatically several months after two courses of sclerotherapy for each patient. No complication and clinical signs of gastrointestinal re-bleeding were observed during the 6-mo endoscopic follow-up...
June 14, 2008: World Journal of Gastroenterology: WJG
B K Chilla, P R Knüsel, Ch L Zollikofer, Th Huber, R A Kubik-Huch
We describe imaging findings and interventional therapy of a 37-year old female patient suffering from chronic pelvic pain with associated vulvar varicosis. MR-angiography showed multiple varices in the left hemi-pelvis, a dilated draining vein from the left ovary as well as a left-sided vulvar varicosis, which was clinically evident. In addition, the MRI suggested insufficiency of the great saphenous vein with varicosis of its tributaries. After crossectomy and infragenual stripping of the great saphenous vein, we proceeded with a left phlebectomy and ligation of the supplying veins...
October 11, 2006: Praxis
Birgit Kahle, Katharina Leng
OBJECTIVE: The objective of this study was to investigate the efficacy of sclerotherapy for varicose veins in a randomized blinded study. METHODS: Twenty-five patients with varicose veins (C(2-4), E(P), A(SP), P(R)) were included. Fourteen subjects received polidocanol (Aethoxysklerol) and 11 patients received normal saline injections. Compression was applied for 1 week. One, 4, and 12 weeks later controls were performed using duplex ultrasonography. The quotient of venous by arterial volume flow was used as quantitative hemodynamic pattern...
May 2004: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
J Martins Pisco, João Alpendre, Daniela Dias Santos, Jorge Branco, Ricardo Jorge, J Pereira Albino, J Daniel Menezes
The female varicocile is associated to the pelvic congestion syndrome that is described. Five patients 31 to 52 years old are presented. Four of them have continuous pelvic pain and the fifth had huge vaginal and vulvar varices. Flebography of the left ovarian vein showed retrograde flux of the dilated vein. Sclerotherapy with Aethoxysklerol 3% was performed. There was an immediate relief of symptoms. During the follow up period between 9 and 12 months the five patients were asymptomatic. There are publications of embolization of the ovarian vein, however the present cases are the first ones in which the selective Sclerotherapy was the only treatment used with good results...
January 2003: Acta Médica Portuguesa
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