keyword
https://read.qxmd.com/read/38539724/opinion-models-election-data-and-political-theory
#1
JOURNAL ARTICLE
Matthias Gsänger, Volker Hösel, Christoph Mohamad-Klotzbach, Johannes Müller
A unifying setup for opinion models originating in statistical physics and stochastic opinion dynamics are developed and used to analyze election data. The results are interpreted in the light of political theory. We investigate the connection between Potts (Curie-Weiss) models and stochastic opinion models in the view of the Boltzmann distribution and stochastic Glauber dynamics. We particularly find that the q-voter model can be considered as a natural extension of the Zealot model, which is adapted by Lagrangian parameters...
February 28, 2024: Entropy
https://read.qxmd.com/read/38515199/sacral-neuromodulation-for-constipation-and-fecal-incontinence-in-children-and-adolescents-study-protocol-of-a-prospective-randomized-trial-on-the-application-of-invasive-vs-non-invasive-technique
#2
RANDOMIZED CONTROLLED TRIAL
Manuel Besendörfer, Annemarie Kirchgatter, Roman Carbon, Christel Weiss, Hanna Müller, Klaus E Matzel, Sonja Diez
BACKGROUND: A therapeutic effect of sacral neuromodulation (SNM) on fecal incontinence (FI) and quality of life has been proven in adults. SNM is, however, rarely used in pediatric cases. The aim of the study is to investigate effects of SNM in pediatric constipation in a prospective parallel-group trial. METHODS: A monocentric, randomized, unblinded, parallel-group trial is conducted. SNM is conducted in the invasive variant and in an innovative, external approach with adhesive electrodes (enteral neuromodulation, ENM)...
March 22, 2024: Trials
https://read.qxmd.com/read/38500424/-comparison-of-talonavicular-cuneiform-joint-fusion-with-bone-grafting-and-without-bone-grafting-in-treatment-of-m%C3%A3-ller-weiss-disease
#3
JOURNAL ARTICLE
Baoli Zou, Wenbo Bai, Guodong Shen, Kaiting Zhang, Jingcheng Xu, Yongzhan Zhu
OBJECTIVE: To compare the effectiveness of talonavicular-cuneiform joint fusion with iliac bone grafting and without bone grafting in the treatment of Müller-Weiss diseases (MWD). METHODS: The clinical data of 44 patients (44 feet) with MWD who received talonavicular-cuneiform joint fusion between January 2017 and November 2022 and met the selection criteria was retrospectively analyzed. Among them, 25 patients were treated with structural iliac bone grafting (bone grafting group) and 19 patients without bone grafting (non-bone grafting group)...
March 15, 2024: Chinese Journal of Reparative and Reconstructive Surgery
https://read.qxmd.com/read/38430535/consequences-of-amyloid-%C3%AE-deficiency-for-the-liver
#4
JOURNAL ARTICLE
Gayane Hrachia Buniatian, Ute Schwinghammer, Roman Tremmel, Holger Cynis, Thomas S Weiss, Ralf Weiskirchen, Volker M Lauschke, Sonia Youhanna, Isbaal Ramos, Maria Valcarcel, Torgom Seferyan, Jens-Ulrich Rahfeld, Vera Rieckmann, Kathrin Klein, Marine Buadze, Victoria Weber, Valentina Kolak, Rolf Gebhardt, Scott L Friedman, Ulrike C Müller, Matthias Schwab, Lusine Danielyan
The hepatic content of amyloid beta (Aβ) decreases drastically in human and rodent cirrhosis highlighting the importance of understanding the consequences of Aβ deficiency in the liver. This is especially relevant in view of recent advances in anti-Aβ therapies for Alzheimer's disease (AD). Here, it is shown that partial hepatic loss of Aβ in transgenic AD mice immunized with Aβ antibody 3D6 and its absence in amyloid precursor protein (APP) knockout mice (APP-KO), as well as in human liver spheroids with APP knockdown upregulates classical hallmarks of fibrosis, smooth muscle alpha-actin, and collagen type I...
March 2, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://read.qxmd.com/read/38391708/high-frequency-language-therapy-with-semantic-feature-analysis-sfa-and-transcranial-direct-current-stimulation-tdcs-a-longitudinal-single-case-report-of-semantic-variant-of-primary-progressive-aphasia-svppa
#5
Katharina Strunk, Sabine Weiss, Horst M Müller
BACKGROUND: The goal of this study was to investigate whether the combination of semantic feature analysis (SFA) and transcranial direct current stimulation (tDCS) is effective in treating word retrieval in the semantic variant of primary progressive aphasia (svPPA) and how long the potential effects last. METHODS: A 56-year-old woman diagnosed with frontotemporal dementia (FTD) and svPPA participated in this longitudinal single-subject design. A total of four 2-week stimulation phases were conducted over a 14-month period, each of which was started depending on the participant's language performance...
January 27, 2024: Brain Sciences
https://read.qxmd.com/read/38385244/m%C3%A3-ller-weiss-disease-midfoot-arthrodesis-in-reduction-vs-malreduction
#6
JOURNAL ARTICLE
Wenbo Bai, Jingcheng Xu, Hongning Zhang, Xue Li, Yunxuan Zou, Guodong Shen, Yongzhan Zhu
BACKGROUND: Midfoot arthrodesis is regarded as the main surgical approach for treating Müller-Weiss disease (MWD). This study aimed to investigate the incidence of postoperative pain during MWD treatment through midfoot reduction or malreduction during arthrodesis and to explore the factors influencing postoperative pain in patients with MWD. METHODS: A total of 67 patients with MWD were recruited and divided into two groups according to whether midfoot alignment was reduced: reduction group ( n  = 38) and malreduction group ( n  = 29)...
February 22, 2024: Foot & Ankle International
https://read.qxmd.com/read/38305079/differences-in-neonatal-gastric-tubes-during-insertion-into-a-3d-model-in-relation-to-risk-of-potential-perforation
#7
JOURNAL ARTICLE
Hilda-Brigitta Bartos, Sonja Diez, Alexander König, Jannis Görlach, Manuel Besendörfer, Andreas H Mahnken, Karla Drommelschmidt, Christel Weiss, Hanna Müller
OBJECTIVES: Perforation of esophagus or stomach is a potential complication during and after insertion of a gastric tube in neonates. The aim of this study was to analyze different types of gastric tubes in a three-dimensional (3D) model of neonatal esophagus and stomach regarding potential perforations. METHODS: A 3D model of esophagus and stomach was created based on computed tomography data of a term neonate. Three types of gastric tubes were inserted into the 3D model, the localization was examined by radioscopy and the behavior, stiffness and manageability of each gastric tube was evaluated...
February 2, 2024: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/38259113/functional-and-radiologic-outcomes-of-degenerative-versus-traumatic-full-thickness-rotator-cuff-tears-involving-the-supraspinatus-tendon
#8
JOURNAL ARTICLE
Cornelia Baum, Laurent Audigé, Thomas Stojanov, Sebastian A Müller, Christian Candrian, Andreas M Müller, Claudio Rosso, Lena Fankhauser, Gernot Willscheid, Philipp Moroder, Doruk Akgün, Victor Danzinger, Henry Gebauer, Jan-Philipp Imiolczyk, Katrin Karpinski, Lucca Lacheta, Marvin Minkus, Alp Paksoy, Eduardo Samaniego, Kathi Thiele, Isabella Weiss, Thomas Suter, Julia Müller-Lebschi, Sebastian Mueller, Markus Saner, Claudia Haag-Schumacher, Giorgio Tamborrini-Schütz, Mai Lan Dao Trong, Carlos Buitrago-Tellez, Julian Hasler, Ulf Riede, Sandra Weber, Beat Moor, Matthias Biner, Sarah Fournier, Nicolas Gallusser, Deborah Marietan, Sebastien Pawlak, Christoph Spormann, Britta Hansen, Nadja Mamisch, Holger Durchholz, Jakob Bräm, Gregory Cunningham, Abed Kourhani, Sarah Ossipow, Patricia Simao, Alexandre Lädermann, Rainer Egli, Stephanie Erdbrink, Remy Flückiger, Paolo Lombardo, Tawan Pinworasarn, Philipp Scacchi, Johannes Weihs, Matthias Zumstein, Matthias Flury, Ralph Berther, Christine Ehrmann, Larissa Hübscher, David Schwappach, Karim Eid, Susanne Bensler, Yannick Fritz, Nisha Grünberger, Philipp Kriechling, Daniel Langthaler, Richard Niehaus, Raffaela Nobs, Emanuel Benninger, Quintin de Groot, Aleksis Doert, Sebastian Ebert, Philemon Grimm, Fabian Mottier, Markus Pisan, Jan Schätz, Ariane Schwank, Julian Wiedenbach, Markus Scheibel, Laurent Audigé, Frederik Bellmann, Daniela Brune, Marije de Jong, Stefan Diermayr, David Endell, Marco Etter, Florian Freislederer, Nikitas Gkikopoulos, Michael Glanzmann, Cécile Grobet, Christian Jung, Fabrizio Moro, Philipp Moroder, Ralph Ringer, Jan Schätz, Hans-Kaspar Schwyzer, Béatrice Weber, Martina Wehrli, Barbara Wirth, Manuela Nötzli, Anne Franz, Jörg Oswald, Birgit Steiger, Yacine Ameziane, Christopher Child, Giovanni Spagna, Christian Candrian, Filippo Del Grande, Pietro Feltri, Giuseppe Filardo, Francesco Marbach, Florian Schönweger, Bernhard Jost, Michael Badulescu, Stephanie Lüscher, Fabian Napieralski, Lena Öhrström, Martin Olach, Jan Rechsteiner, Jörg Scheler, Christian Spross, Vilijam Zdravkovic, Matthias A Zumstein, Adrian Chlasta, Kate Gerber, Annabel Hayoz, Julia Müller-Lebschi, Frederick Schuster, Karl Wieser, Paul Borbas, Samy Bouaicha, Roland Camenzind, Sabrina Catanzaro, Christian Gerber, Florian Grubhofer, Anita Hasler, Bettina Hochreiter, Roy Marcus, Farah Selman, Reto Sutter, Sabine Wyss, Christian Appenzeller-Herzog, Soheila Aghlmandi, Ilona Ahlborn, Cornelia Baum, Franziska Eckers, Kushtrim Grezda, Simone Hatz, Sabina Hunziker, Thomas Stojanov, Mohy Taha, Giorgio Tamborrini-Schütz, Andreas Marc Mueller
BACKGROUND: Arthroscopic rotator cuff repair (ARCR) is among the most commonly performed orthopaedic procedures. Several factors-including age, sex, and tear severity-have been identified as predictors for outcome after repair. The influence of the tear etiology on functional and structural outcome remains controversial. PURPOSE: To investigate the influence of tear etiology (degenerative vs traumatic) on functional and structural outcomes in patients with supraspinatus tendon tears...
February 2024: American Journal of Sports Medicine
https://read.qxmd.com/read/38236786/effect-of-a-brief-psychological-intervention-for-common-mental-disorders-on-hiv-viral-suppression-a-non-randomised-controlled-study-of-the-friendship-bench-in-zimbabwe
#9
JOURNAL ARTICLE
Victoria Simms, Melanie A Abas, Monika Müller, Epiphania Munetsi, Lloyd Dzapasi, Helen A Weiss, Dixon Chibanda
BACKGROUND: For people living with co-morbid HIV and common mental disorders (CMD), it is not known whether a brief psychological intervention for CMD can improve HIV viral suppression. METHODS: We conducted a prospective cohort study in eight primary care clinics in Harare, Zimbabwe, enrolling adults with co-morbid HIV and CMD. Six clinics provided the Friendship Bench (FB), a brief psychological intervention for CMD based on problem-solving therapy, delivered by lay counsellors...
2024: PLOS Glob Public Health
https://read.qxmd.com/read/38211457/a-preliminary-study-on-the-effect-of-trauma-focused-therapies-on-sexual-dysfunctions-in-women-with-ptsd-after-childhood-abuse
#10
JOURNAL ARTICLE
Regina Steil, Judith Weiss, Pia Bornefeld-Ettmann, Kathlen Priebe, Nikolaus Kleindienst, Meike Müller-Engelmann
BACKGROUND: Posttraumatic stress disorder (PTSD) is often associated with female sexual dysfunctions (FSD). However, little is known about the impact of therapies for PTSD on FSD according to DSM-5 criteria. AIM/OBJECTIVE: To examine if sexual functioning diagnosed according to DSM-5 criteria improves after treatment for PTSD in women with a PTSD diagnosis after interpersonal child abuse. METHOD: FSD according to DSM-5 criteria were assessed with the structured clinical interview SISEX in N = 152 female participants (mean age = 36...
January 8, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38196336/associations-of-menstrual-cycle-and-progesterone-to-estradiol-ratio-with-alcohol-consumption-in-alcohol-use-disorder-a-sex-separated-multicenter-longitudinal-study
#11
JOURNAL ARTICLE
Sabine Hoffmann, Sarah Gerhardt, Christiane Mühle, Iris Reinhard, Dominic Reichert, Patrick Bach, Rafat Boroumand-Jazi, Christine Kuehner, Alvaro Aguilera, Acelya Aslan, Nadja S Bahr, Matthew Belanger, Friederike Deeken, Claudia Ebrahimi, Pascale C Fischbach, Marvin Ganz, Maria Garbusow, Charlotte M Großkopf, Marie Heigert, Angela Hentschel, Damian Karl, Shuyan Liu, Massimiliano Mazza, Patricia Pelz, Mathieu Pinger, Matthias Reichl, Carlotta Riemerschmid, Annika Rosenthal, Johannes Steffen, Jens Strehle, Friederike Wedemeyer, Franziska Weiss, Julia Wenzel, Gesine Wieder, Alfred Wieland, Judith Zaiser, Hilmar G Zech, Sina Zimmermann, Johannes Kornhuber, Christian P Müller, Wolfgang H Sommer, Rainer Spanagel, Tobias Banaschewski, Lorenz Deserno, Ulrich W Ebner-Priemer, Herta Flor, Peter Kirsch, Marcella Rietschel, Sabine Vollstädt-Klein, Henrik Walter, Andreas Meyer-Lindenberg, Michael A Rapp, Stephanie Witt, Michael N Smolka, Andreas Heinz, Heike Tost, Falk Kiefer, Markus Reichert, Bernd Lenz
OBJECTIVE: Alcohol use disorder (AUD) constitutes a critical public health issue and has sex-specific characteristics. Initial evidence suggests that progesterone and estradiol might reduce or increase alcohol intake, respectively. However, there is a need for a better understanding of how the menstrual cycle in females and the ratio of progesterone to estradiol in females and males influence alcohol use patterns in individuals with AUD. METHODS: In this sex-separated multicenter longitudinal study, the authors analyzed 12-month data on real-life alcohol use (from 21,460 smartphone entries), menstrual cycle, and serum progesterone-to-estradiol ratios (from 667 blood samples at four individual study visits) in 74 naturally cycling females and 278 males with AUD between 2020 and 2022, using generalized and general linear mixed modeling...
January 10, 2024: American Journal of Psychiatry
https://read.qxmd.com/read/38071194/sentence-completion-in-progressive-supranuclear-palsy-following-transcranial-direct-current-stimulation
#12
JOURNAL ARTICLE
Johanna Scholtz, Sabine Weiss, Christoph Redecker, Horst M Müller
Progressive supranuclear palsy (PSP) is an atypical Parkinsonian disorder which results in deterioration of motor and cognitive skills, including language disorders such as impaired word retrieval. While there is evidence of successful use of tDCS to improve word fluency in PSP, little is known about the effectiveness of brain stimulation for word retrieval in sentence context. Therefore, we investigated whether tDCS reduces sentence completion time in PSP patients. In this sham-controlled, triple-blinded crossover study, anodal tDCS (atDCS) was applied over the left Broca's area at 2 mA for 20 min (n = 23)...
December 9, 2023: NPJ Parkinson's Disease
https://read.qxmd.com/read/38061622/outcomes-of-selective-arthrodesis-based-on-joints-affected-in-33-feet-with-m%C3%A3-ller-weiss-disease
#13
JOURNAL ARTICLE
John Wong-Chung, Andrew Blythe, Matthew Lynch-Wong, Raymond McKenna, Alistair Wilson, Michael Stephens
No consensus exists regarding operative treatment of Müller-Weiss disease (MWD). Its only classification is based solely on Méary's angle and serves neither as guide to management nor prognosis. We report on 33 feet that underwent surgery following failed conservative management. Treatment was directed towards joint(s) involved, as determined by clinical examination, plain radiography and SPECT-CT. Thus, surgery consisted of isolated talonavicular in 6 feet, triple in 8, subtalar and talonavicular in 7, talonaviculocuneiform in 4, talonaviculocuneiform with interpositional tricortical iliac crest graft in 6 and pantalar arthrodesis in 2...
December 5, 2023: Journal of Foot and Ankle Surgery
https://read.qxmd.com/read/38034835/high-sensitive-cardiac-troponin-i-hs-ctni-concentrations-in-newborns-diagnosed-with-spinal-muscular-atrophy
#14
JOURNAL ARTICLE
Jessika Johannsen, Deike Weiss, Joenna Driemeyer, Jakob Olfe, Fridrike Stute, Ferdinand Müller, Marion Schütt, Regina Trollmann, Heike Kölbel, Ulrike Schara-Schmidt, Janbernd Kirschner, Astrid Pechmann, Astrid Blaschek, Veronka Horber, Jonas Denecke
BACKGROUND: Spinal muscular atrophy (SMA) is a genetic neurodegenerative disease leading to muscular weakness and premature death. Three therapeutic options are currently available including gene replacement therapy (GRT), which is potentially cardiotoxic. High-sensitive cardiac troponin I (hs-cTnI) is widely used to monitor potential cardiac contraindications or side effects of GRT, but reference data in healthy newborns are limited and lacking in neonates with SMA. The aim of this study is to determine the range of pre-therapeutic hs-cTnI concentrations in neonates with SMA and to provide guidance for the assessment of these values...
2023: Frontiers in Pediatrics
https://read.qxmd.com/read/37991136/renal-amyloid-a-amyloidosis-in-cats-characterization-of-proteinuria-and-biomarker-discovery-and-associations-with-kidney-histology
#15
JOURNAL ARTICLE
Carlo Palizzotto, Felippo Ferri, Carolina Callegari, Francesco Rossi, Marcello Manfredi, Laura Carcangiu, Gabriele Gerardi, Silvia Ferro, Laura Cavicchioli, Elizabeth Müller, Marco Weiss, Anne-Catherine Vogt, Francesca Lavatelli, Stefano Ricagno, Karyl Hurley, Eric Zini
BACKGROUND: Amyloid A (AA) amyloidosis is a protein misfolding disease arising from serum amyloid A (SAA). Systemic AA amyloidosis recently was shown to have a high prevalence in shelter cats in Italy and was associated with azotemia and proteinuria. OBJECTIVES: Investigate urine protein profiles and diagnostic biomarkers in cats with renal AA amyloidosis. ANIMALS: Twenty-nine shelter cats. METHODS: Case-control study...
November 22, 2023: Journal of Veterinary Internal Medicine
https://read.qxmd.com/read/37919292/diamond-preservation-in-the-lithospheric-mantle-recorded-by-olivine-in-kimberlites
#16
JOURNAL ARTICLE
Andrea Giuliani, David Phillips, D Graham Pearson, Soumendu Sarkar, Alex A Müller, Yaakov Weiss, Robin Preston, Michael Seller, Zdislav Spetsius
The diamond potential of kimberlites is difficult to assess due to several mantle and magmatic processes affecting diamond content. Traditionally, initial evaluations are based on the compositions of mantle-derived minerals (garnet, chromite, clinopyroxene), which allow an assessment of pressure-temperature conditions and lithologies suitable for diamond formation. Here we explore a complementary approach that considers the conditions of diamonds destruction by interaction with melts/fluids (metasomatism). We test the hypothesis that carbonate-rich metasomatism related to kimberlite melt infiltration into the deep lithosphere is detrimental to diamond preservation...
November 2, 2023: Nature Communications
https://read.qxmd.com/read/37860858/is-adherence-to-dialectic-behaviour-therapy-for-post-traumatic-stress-disorder-ptsd-and-cognitive-processing-therapy-related-to-treatment-outcome-in-ptsd-after-childhood-abuse
#17
JOURNAL ARTICLE
Regina Steil, Judith Weiss, Meike Müller-Engelmann, Clara Dittmann, Kathlen Priebe, Nikolaus Kleindienst, Thomas Fydrich, Ulrich Stangier
Background: Literature on the association between therapist adherence and treatment success in the treatment of post-traumatic stress disorder (PTSD) is scarce, and the results are mixed. Objective: To examine the relationship between therapist adherence to dialectical behaviour therapy for PTSD (DBT-PTSD) and cognitive processing therapy (CPT) on treatment outcome in women with PTSD and emotion regulation difficulties after interpersonal childhood abuse. Method: Videotaped therapy sessions from 160 female participants of a large randomized controlled trial [Bohus, M...
2023: European Journal of Psychotraumatology
https://read.qxmd.com/read/37850567/a-novel-update-on-the-management-of-m%C3%A3-ller-weiss-disease-presentation-of-a-treatment-algorithm
#18
JOURNAL ARTICLE
Chayanin Angthong, Alastair S E Younger, Bavornrit Chuckpaiwong, Thos Harnroongroj, Andrea Veljkovic
OBJECTIVE: Müller-Weiss disease (MWD) is a challenging condition involving the perinavicular region in the initial stages and subsequently the entire foot in the later stages. The goal of this article is to describe the pathomechanics, clinical evaluation, and nonoperative and operative treatment, including a treatment algorithm, based on current evidence and the combined authors' experience. DESIGN: We review the related articles and summarize the information about this condition...
October 18, 2023: Cartilage
https://read.qxmd.com/read/37794016/european-and-multi-ancestry-genome-wide-association-meta-analysis-of-atopic-dermatitis-highlights-importance-of-systemic-immune-regulation
#19
JOURNAL ARTICLE
Ashley Budu-Aggrey, Anna Kilanowski, Maria K Sobczyk, Suyash S Shringarpure, Ruth Mitchell, Kadri Reis, Anu Reigo, Reedik Mägi, Mari Nelis, Nao Tanaka, Ben M Brumpton, Laurent F Thomas, Pol Sole-Navais, Christopher Flatley, Antonio Espuela-Ortiz, Esther Herrera-Luis, Jesus V T Lominchar, Jette Bork-Jensen, Ingo Marenholz, Aleix Arnau-Soler, Ayoung Jeong, Katherine A Fawcett, Hansjorg Baurecht, Elke Rodriguez, Alexessander Couto Alves, Ashish Kumar, Patrick M Sleiman, Xiao Chang, Carolina Medina-Gomez, Chen Hu, Cheng-Jian Xu, Cancan Qi, Sarah El-Heis, Philip Titcombe, Elie Antoun, João Fadista, Carol A Wang, Elisabeth Thiering, Baojun Wu, Sara Kress, Dilini M Kothalawala, Latha Kadalayil, Jiasong Duan, Hongmei Zhang, Sabelo Hadebe, Thomas Hoffmann, Eric Jorgenson, Hélène Choquet, Neil Risch, Pål Njølstad, Ole A Andreassen, Stefan Johansson, Catarina Almqvist, Tong Gong, Vilhelmina Ullemar, Robert Karlsson, Patrik K E Magnusson, Agnieszka Szwajda, Esteban G Burchard, Jacob P Thyssen, Torben Hansen, Line L Kårhus, Thomas M Dantoft, Alexander C S N Jeanrenaud, Ahla Ghauri, Andreas Arnold, Georg Homuth, Susanne Lau, Markus M Nöthen, Norbert Hübner, Medea Imboden, Alessia Visconti, Mario Falchi, Veronique Bataille, Pirro Hysi, Natalia Ballardini, Dorret I Boomsma, Jouke J Hottenga, Martina Müller-Nurasyid, Tarunveer S Ahluwalia, Jakob Stokholm, Bo Chawes, Ann-Marie M Schoos, Ana Esplugues, Mariona Bustamante, Benjamin Raby, Syed Arshad, Chris German, Tõnu Esko, Lili A Milani, Andres Metspalu, Chikashi Terao, Katrina Abuabara, Mari Løset, Kristian Hveem, Bo Jacobsson, Maria Pino-Yanes, David P Strachan, Niels Grarup, Allan Linneberg, Young-Ae Lee, Nicole Probst-Hensch, Stephan Weidinger, Marjo-Riitta Jarvelin, Erik Melén, Hakon Hakonarson, Alan D Irvine, Deborah Jarvis, Tamar Nijsten, Liesbeth Duijts, Judith M Vonk, Gerard H Koppelmann, Keith M Godfrey, Sheila J Barton, Bjarke Feenstra, Craig E Pennell, Peter D Sly, Patrick G Holt, L Keoki Williams, Hans Bisgaard, Klaus Bønnelykke, John Curtin, Angela Simpson, Clare Murray, Tamara Schikowski, Supinda Bunyavanich, Scott T Weiss, John W Holloway, Josine L Min, Sara J Brown, Marie Standl, Lavinia Paternoster
Atopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide association studies (GWAS) have identified 71 associated loci. In the current study we conducted the largest AD GWAS to date (discovery N = 1,086,394, replication N = 3,604,027), combining previously reported cohorts with additional available data. We identified 81 loci (29 novel) in the European-only analysis (which all replicated in a separate European analysis) and 10 additional loci in the multi-ancestry analysis (3 novel)...
October 4, 2023: Nature Communications
https://read.qxmd.com/read/37753639/does-treatment-specific-disorder-specific-or-general-therapeutic-competence-predict-symptom-reduction-in-posttraumatic-stress-disorder
#20
RANDOMIZED CONTROLLED TRIAL
Regina Steil, Judith Weiss, Meike Müller-Engelmann, Clara Dittmann, Kathlen Priebe, Nikolaus Kleindienst, Thomas Fydrich, Ulrich Stangier
Background: Literature on the association between therapist competence and treatment success in posttraumatic stress disorder (PTSD) treatments is scarce and results are mixed. Aims/Objective: The relationship between different types of therapeutic competence, therapeutic alliance, and PTSD symptom reduction in patients treated with Dialectical Behaviour Therapy for PTSD (DBT-PTSD) or Cognitive Processing Therapy (CPT) was assessed. Competence types were PTSD-specific competence, treatment specific competence, and general competence in cognitive behaviour therapy (CBT)...
2023: European Journal of Psychotraumatology
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