Jordan Harp, Lisa Koehl, Kathryn Van Pelt, Elizabeth Head, Gregory Jicha, William Robertson, Donita Lightner, Ira Lott, Frederick Schmitt
Background and Objectives: To determine whether primitive reflexes serve as an indicator of dementia in adults with Down syndrome (DS), we collected neurologic examination data, cognitive and behavioral assessments, and clinical consensus diagnoses of dementia from 92 adults with DS. Methods: In a cross-sectional, observational study of a regional cohort, χ2 and Fisher exact tests examined individual reflexes across the diagnostic group (no, possible, or probable dementia)...
February 2022: Neurology. Clinical Practice