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Neuromodulation for pain

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https://www.readbyqxmd.com/read/29160571/sacral-neuromodulation-and-pregnancy-results-of-a-national-survey-carried-out-for-the-neuro-urology-committee-of-the-french-association-of-urology-afu
#1
Pauline Roulette, Evelyne Castel-Lacanal, Sylvain Sanson, Romain Caremel, Véronique Phé, Stéphane Bart, Franck Duchêne, Marianne De Sèze, Alexia Even, Andréa Manunta, Maria C Scheiber-Nogueira, Pascal Mouracade, Catherine-Marie Loche, Emmanuel Chartier-Kastler, Alain Ruffion, Gilles Karsenty, Xavier Gamé
AIMS: To assess the impact of sacral neuromodulation (SNM) on pregnancy and vice-versa, by identifying women who had received SNM for lower-urinary tract symptoms (LUTS) and had become pregnant. METHODS: A cross-sectional descriptive study was carried out based on responses to an on-line questionnaire sent to practitioners listed on the InterStim enCaptureTM National Registry. Questions were related to pre-pregnancy health and SNM efficacy, deactivation of the device, its impact on LUTS, childbirth, the infant, its reactivation and postpartum effectiveness...
November 21, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29152818/electrical-stimulation-of-dorsal-root-ganglion-in-the-context-of-pain-a-systematic-review-of-in-vitro-and-in-vivo-animal-model-studies
#2
REVIEW
Ivana Vuka, Katarina Vučić, Tihana Repić, Lejla Ferhatović Hamzić, Damir Sapunar, Livia Puljak
OBJECTIVE: Dorsal root ganglion (DRG) has recently emerged as an attractive target for neuromodulation therapy since primary sensory neurons and their soma in DRGs are important sites for pathophysiologic changes that lead to neuropathic pain. Our aim was to create evidence synthesis about the effects of electrical stimulation of DRG in the context of pain from in vitro and in vivo animal models, analyze methodology and quality of studies in the field. METHODS: For conducting systematic review we searched three data bases: MEDLINE, Embase and Web of Science...
November 20, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/29149156/survival-analysis-of-occipital-nerve-stimulator-leads-placed-under-fluoroscopic-guidance-with-and-without-ultrasonography
#3
James H Jones, Alison Brown, Daniel Moyse, Wenjing Qi, Lance Roy
BACKGROUND: Electrical stimulation of the greater occipital nerves is performed to treat pain secondary to chronic daily headaches and occipital neuralgia. The use of fluoroscopy alone to guide the surgical placement of electrodes near the greater occipital nerves disregards the impact of tissue planes on lead stability and stimulation efficacy. OBJECTIVE: We hypothesized that occipital neurostimulator (ONS) leads placed with ultrasonography combined with fluoroscopy would demonstrate increased survival rates and times when compared to ONS leads placed with fluoroscopy alone...
November 2017: Pain Physician
https://www.readbyqxmd.com/read/29127483/high-definition-transcranial-direct-current-stimulation-of-the-dorsolateral-prefrontal-cortex-for-tinnitus-modulation-a-preliminary-trial
#4
Giriraj Singh Shekhawat, Sven Vanneste
Tinnitus is the perception of sound in the absence of its external source. Non-invasive neuromodulation techniques have been used in the past decade to investigate the impact of stimulation on tinnitus perception. The objective is to invest the impact of high-definition transcranial direct current stimulation (HD-tDCS) of dorsolateral prefrontal cortex (DLPFC) stimulation on tinnitus loudness and annoyance. Thirteen participants underwent two sessions of HD-tDCS (real and sham) in a double blind, sham controlled, randomized trial...
November 10, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/29115915/neuromodulation-in-multiple-sclerosis
#5
Hesham Abboud, Eddie Hill, Junaid Siddiqui, Alessandro Serra, Benjamin Walter
Neuromodulation, or the utilization of advanced technology for targeted electrical or chemical neuronal stimulation or inhibition, has been expanding in several neurological subspecialties. In the past decades, immune-modulating therapy has been the main focus of multiple sclerosis (MS) research with little attention to neuromodulation. However, with the recent advances in disease-modifying therapies, it is time to shift the focus of MS research to neuromodulation and restoration of function as with other neurological subspecialties...
November 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/29102296/sacral-neuromodulation-for-faecal-incontinence-10-years-experience-at-a-scottish-tertiary-centre
#6
Hoey Koh, Stephen McSorley, Sarah Hunt, Martha Quinn, Graham MacKay, John Anderson
INTRODUCTION: Sacral nerve stimulation (SNS) is increasingly popular in the management of faecal incontinence. This paper reports the first 10-year experience of SNS in the management of faecal incontinence at a tertiary referral centre. Data was collected in a prospectively maintained database. RESULTS: In total 130 patients were referred. The majority were women (94%) under 75-year-old (98%). Seven patients were found to have full-thickness rectal prolapse at the initial work-up and proceeded to rectopexy...
October 25, 2017: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/29099093/functional-dyspepsia
#7
REVIEW
Paul Enck, Fernando Azpiroz, Guy Boeckxstaens, Sigrid Elsenbruch, Christine Feinle-Bisset, Gerald Holtmann, Jeffrey M Lackner, Jukka Ronkainen, Michael Schemann, Andreas Stengel, Jan Tack, Stephan Zipfel, Nicholas J Talley
Functional dyspepsia is one of the most prevalent functional gastrointestinal disorders. Functional dyspepsia comprises three subtypes with presumed different pathophysiology and aetiology: postprandial distress syndrome (PDS), epigastric pain syndrome (EPS) and a subtype with overlapping PDS and EPS features. Functional dyspepsia symptoms can be caused by disturbed gastric motility (for example, inadequate fundic accommodation or delayed gastric emptying), gastric sensation (for example, sensations associated with hypersensitivity to gas and bloating) or gastric and duodenal inflammation...
November 3, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29094305/noradrenergic-fiber-sprouting-and-altered-transduction-in-neuropathic-prefrontal-cortex
#8
Steven Cordeiro Matos, Maria Zamfir, Geraldine Longo, Alfredo Ribeiro-da-Silva, Philippe Séguéla
Functional changes in hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels have been shown to contribute to medial prefrontal (mPFC) hyperexcitability after peripheral nerve injury. A reduction in the open probability of these neuronal channels might be relevant since this can enhance membrane input resistance and synaptic summation. However, the molecular mechanisms underlying neuropathy-associated alterations in HCN channel activity remain elusive. Using the spared nerve injury model of neuropathic pain in Long-Evans rats, we first discovered a significant increase in noradrenergic innervation within the mPFC of nerve-injured compared to control animals...
November 1, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/29077143/-neuromodulation-can-be-effective-in-patients-with-medically-unexplained-symptoms
#9
M van Beilen, H Tieleman
BACKGROUND: Neuromodulation may influence abnormal brain activation patterns in medically unexplained symptoms (MUS). AIM: To assess the importance and direction of future studies on patients with MUS. METHOD: We describe the results of the first studies on patients with functional neurological symptom disorder (fNSD) and chronic pain. RESULTS: Clinically relevant improvements in the health condition of a substantial number of patients with fnsd have been reported...
2017: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/29077132/-brain-stimulation-the-most-direct-form-of-neurostimulation
#10
T A de Graaf, C Baeken, P Sienaert, A Aleman, A T Sack
BACKGROUND: Brain stimulation is the most direct form of neuromodulation. Direct brain stimulation is an older procedure that has taken various forms, but 'non-invasive brain stimulation' is a more recent development. AIM: To provide an overview of the current arsenal of non-invasive brain stimulation techniques. METHOD: We discuss the underlying principles, the pros and cons, and the applicability of non-invasive brain stimulation in experimental research and treatment of neuropsychiatric disorders...
2017: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/29042375/non-invasive-brain-stimulation-interventions-for-management-of-chronic-central-neuropathic-pain-a-scoping-review-protocol
#11
Mei Lin Chen, Lin Yao, Jennifer Boger, Kathryn Mercer, Benjamin Thompson, Ning Jiang
INTRODUCTION: Pain can affect people regardless of age, gender or ethnicity. Chronic central neuropathic pain (CCNP) is a debilitating condition that affects populations such as stroke survivors, amputees, spinal cord injury patients and patients with multiple sclerosis, with prevalence rates between 30% and 80%. This condition can be caused by a lesion or disease affecting the somatosensory system. CCNP is notoriously drug resistant, and few effective CCNP treatment or management strategies exist...
October 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29030173/a-novel-miniature-wireless-neurostimulator-in-the-management-of-chronic-craniofacial-pain-preliminary-results-from-a-prospective-pilot-study
#12
Richard L Weiner, Carlos Montes Garcia, Niek Vanquathem
OBJECTIVE: To report a novel wireless neuromodulation system for treatment of refractory craniofacial pain. BACKGROUND: Previous studies utilizing peripheral nerve stimulation (PNS) of the occipital and trigeminal nerves reported positive outcomes for alleviating neuropathic pain localized to the craniofacial and occipital areas. However several technological limitations and cosmetic concerns inhibited a more widespread acceptance and use of neuromodulation. Also, a relatively high incidence of adverse events like electrode erosions, dislocation, wire fracture and/or infection at the surgical site mandates a change in our approach to neuromodulation technology and implant techniques in the craniofacial region...
October 10, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29026048/spinal-cord-stimulation-for-chronic-non-cancer-pain-a-review-of-current-evidence-and-practice
#13
S Sc Wong, C W Chan, C W Cheung
Spinal cord stimulation provides analgesia through electrical stimulation of the dorsal column of the spinal cord via electrode leads placed into the epidural space. In traditional tonic stimulation, a painful sensation is replaced with paraesthesia. Spinal cord stimulation is effective in reducing neuropathic pain, enhancing function, and improving quality of life in different chronic pain conditions. Currently, there is most evidence to support its use for failed back surgery syndrome when multidisciplinary conventional management is unsuccessful...
October 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/29016994/neuromodulation-in-postherpetic-neuralgia-case-reports-and-review-of-the-literature
#14
Svetlana Kurklinsky, Scott C Palmer, Mack J Arroliga, Salim M Ghazi
Objective: Postherpetic neuralgia (PHN) is common in the United States. Current treatment options for PHN are fairly limited. Spinal cord stimulation (SCS) and peripheral nerve stimulation (PNS) are considered mostly experimental and still rarely performed in patients with PHN. Design: Two case reports and a review of the literature. Setting: Tertiary academic medical center. Methods: 1) Pubmed, Ovid, and EBMR databases were searched for all reports that had the following key words: postherpetic neuralgia, spinal cord stimulation, and peripheral nerve stimulation...
July 17, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29016867/the-response-of-the-primary-motor-cortex-to-neuromodulation-is-altered-in-chronic-low-back-pain-a-preliminary-study
#15
Siobhan M Schabrun, Emma Burns, Tribikram Thapa, Paul Hodges
Objective: Neuromodulation is increasingly investigated for the treatment of low back pain (LBP). However, the neurophysiological effects of common neuromodulatory techniques (anodal transcranial direct current stimulation [tDCS] and peripheral electrical stimulation [PES]) have not been investigated in people with chronic LBP. Here we aimed to compare the effect of three neuromodulatory protocols (anodal tDCS, high intensity PES, and a priming protocol of combined tDCS/PES) on primary motor cortex (M1) excitability in people with and without chronic LBP...
July 17, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28975844/microvascular-decompression-or-neuromodulation-in-patients-with-sunct-and-trigeminal-neurovascular-conflict
#16
Samih Hassan, Susie Lagrata, Andrew Levy, Manjit Matharu, Ludvic Zrinzo
Objectives To assess the effectiveness of neuromodulation and trigeminal microvascular decompression (MVD) in patients with medically-intractable short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT). Methods Two patients with medically refractory SUNCT underwent MVD following beneficial but incomplete response to neuromodulation (occipital nerve stimulation and deep brain stimulation). MRI confirmed neurovascular conflict with the ipsilateral trigeminal nerve in both patients...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28973357/a-prospective-analysis-of-neuromonitoring-for-confirmation-of-lead-placement-in-dorsal-root-ganglion-stimulation
#17
Steven M Falowski, Andreas Dianna
BACKGROUND: Dorsal root ganglion stimulation is a neuromodulation therapy used for chronic neuropathic pain. Typically, patients are awakened intraoperatively to confirm adequate placement. OBJECTIVE: To determine whether neuromonitoring can confirm placement in an asleep patient. METHODS: This is a prospective analysis of 12 leads placed in 6 patients. Lead confirmation was confirmed by awake intraoperative testing, as well as asleep testing utilizing neuromonitoring...
August 2, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28967986/long-term-functional-outcomes-of-s3-sacral-neuromodulation-for-the-treatment-of-idiopathic-overactive-bladder
#18
Salima Ismail, Emmanuel Chartier-Kastler, Marie-Aimée Perrouin-Verbe, Johan Rose-Dite-Modestine, Pierre Denys, Véronique Phé
OBJECTIVES: To assess the long-term functional outcomes of sacral neuromodulation (SNM) in the treatment of refractory idiopathic overactive bladder (IOAB) and to determine predictive factors for success. MATERIALS AND METHODS: To obtain long-term data, all consecutive patients suffering from IOAB and treated by SNM at a single tertiary care center between December 1996 and December 2004 were included. Data regarding patient demographics, past medical, and surgical history, bladder diary, complications as well as device revision and removal rates were collected...
October 2, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28961366/success-using-neuromodulation-with-burst-sunburst-study-results-from-a-prospective-randomized-controlled-trial-using-a-novel-burst-waveform
#19
Timothy Deer, Konstantin V Slavin, Kasra Amirdelfan, Richard B North, Allen W Burton, Thomas L Yearwood, Ed Tavel, Peter Staats, Steven Falowski, Jason Pope, Rafael Justiz, Alain Y Fabi, Alexander Taghva, Richard Paicius, Timothy Houden, Derron Wilson
OBJECTIVE: The purpose of the multicenter, randomized, unblinded, crossover success using neuromodulation with BURST (SUNBURST) study was to determine the safety and efficacy of a device delivering both traditional tonic stimulation and burst stimulation to patients with chronic pain of the trunk and/or limbs. METHODS: Following a successful tonic trial, 100 subjects were randomized to receive one stimulation mode for the first 12 weeks, and then the other stimulation mode for the next 12 weeks...
September 29, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28961359/prevalence-and-cost-analysis-of-complex-regional-pain-syndrome-crps-a-role-for-neuromodulation
#20
Aladine A Elsamadicy, Siyun Yang, Amanda R Sergesketter, Bilal Ashraf, Lefko Charalambous, Hanna Kemeny, Tiffany Ejikeme, Xinru Ren, Promila Pagadala, Beth Parente, Jichun Xie, Shivanand P Lad
OBJECTIVE: The diagnosis and treatment of complex regional pain syndrome (CRPS) is challenging and there is a paucity of data describing its overall cost burden and quantifying its impact on the US healthcare system. The aim of this study was to assess the prevalence and healthcare utilization costs associated with CRPS. MATERIALS AND METHODS: A retrospective longitudinal study was performed using the Truven MarketScan® database to identify patients with a new indexed diagnosis of CRPS (Type I, II, or both) from 2001 to 2012...
September 29, 2017: Neuromodulation: Journal of the International Neuromodulation Society
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