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Elastography

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https://www.readbyqxmd.com/read/28433440/spatial-compounding-technique-to-obtain-rotation-elastogram-a-feasibility-study
#1
AliArshad Kothawala, Sowmiya Chandramoorthi, N Ravi Kiran Reddy, Arun Kumar Thittai
The perception of stiffness and slipperiness of a breast mass on palpation is used by physicians to assess the level of suspicion of a lesion as being malignant or benign. However, most current ultrasound elastography imaging methods provide only stiffness-related information. There is no existing approach that provides information about the local rigid body rotation undergone by only a loosely bonded, asymmetrically oriented lesion subjected to a small quasi-static compression. The inherent poor lateral resolution in ultrasound imaging poses a limitation in estimating the local rigid body rotation...
April 19, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28431795/shear-wave-liver-elastography-with-a-propagation-map-diagnostic-performance-and-inter-observer-correlation-for-hepatic-fibrosis-in-chronic-hepatitis
#2
Eun Sun Lee, Jong Beum Lee, Hwi Ryong Park, Jeongin Yoo, Ji In Choi, Hyun Woong Lee, Hyung Joon Kim, Byung Ihn Choi, Hyun Jeong Park, Sung Bin Park
The aim of this study was to determine the performance of shear wave elastography (SWE) with a propagation map in the diagnosis of hepatic fibrosis, and to assess its reliability with transient elastography (TE) as the reference standard. Our prospective study included 115 consecutive patients with suspected or alleged chronic hepatitis. Patients underwent SWE by two different operators and TE by sonographers on the same day. The correlation coefficient of the intra-class correlation test between an experienced radiologist and a third-year radiology resident was 0...
April 18, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28428826/the-reliability-of-shear-elastic-modulus-measurement-of-the-ankle-plantar-flexion-muscles-is-higher-at-dorsiflexed-position-of-the-ankle
#3
Junya Saeki, Tome Ikezoe, Masatoshi Nakamura, Satoru Nishishita, Noriaki Ichihashi
BACKGROUND: Excessive stiffness of lower limb muscles is associated with sports injuries. Therefore, the identification of a reliable measurement of the shear elastic modulus of various ankle plantar flexion muscles is required to evaluate lower leg sports injuries. This study investigated the reliable measurement of the shear elastic modulus of the ankle plantar flexion muscles at different ankle positions. METHODS: Twenty-three healthy young men (25.3 ± 3...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/28426437/supersonic-transient-magnetic-resonance-elastography-for-quantitative-assessment-of-tissue-elasticity
#4
Yu Liu, Jingfei Liu, Brett Z Fite, Josquin Foiret, Asaf Ilovitsh, J Kent Leach, Erik Dumont, Charles F Caskey, Katherine W Ferrara
Non-invasive, quantitative methods to assess the properties of biological tissues are needed for many therapeutic and tissue engineering applications. Magnetic resonance elastography (MRE) has historically relied on external vibration to generate periodic shear waves. In order to focally assess a biomaterial or to monitor the response to ablative therapy, the interrogation of a specific region of interest by a focused beam is desirable and transient MRE (t-MRE) techniques have previously been developed to accomplish this goal...
April 20, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28425404/transient-elastography-vs-aspartate-aminotransferase-to-platelet-ratio-index-in-hepatitis-c-a-meta-analysis
#5
A Z Mattos, A A Mattos
BACKGROUND AND RATIONALE: Many different non-invasive methods have been studied with the purpose of staging liver fibrosis. The objective of this study was verifying if transient elastography is superior to aspartate aminotransferase to platelet ratio index for staging fibrosis in patients with chronic hepatitis C. MATERIAL AND METHODS: A systematic review with meta-analysis of studies which evaluated both non-invasive tests and used biopsy as the reference standard was performed...
May 2017: Annals of Hepatology
https://www.readbyqxmd.com/read/28425401/mre-in-nafld-promising-but-further-validation-is-required
#6
John D Ryan, Emmanuel A Tsochatzis
MR elastography is a novel method for non-invasive fibrosis assessment, not yet sufficiently validated. In a recent study in 104 patients Park, Gastroenterology 2017; 152: 598-602), MRE was compared to transient elastography for the diagnosis of fibrosis is nonalcoholic fatty liver disease. The current viewpoint critically appraises this study.
May 2017: Annals of Hepatology
https://www.readbyqxmd.com/read/28424923/shear-wave-velocity-of-the-healthy-thyroid-gland-in-children-with-acoustic-radiation-force-impulse-elastography
#7
Meltem Ceyhan Bilgici, Dilek Sağlam, Semra Delibalta, Serap Yücel, Leman Tomak, Muzaffer Elmalı
PURPOSE: Acoustic radiation force impulse imaging is a kind of shear wave elastography that can be used in children for differentiating thyroid pathologies. Possible changes in the healthy thyroid gland in children may create difficulties in the use of shear wave velocities (SWV) in thyroid pathologies. The aim of this study was to define the normal values of SWV for the healthy thyroid gland in children, elucidate the correlation of the SWV values with potential influencing factors, and evaluate intra-operator reproducibility of the SWV...
April 19, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/28422391/mr-elastography-detection-of-early-viscoelastic-response-of-the-murine-hippocampus-to-amyloid-%C3%AE-accumulation-and-neuronal-cell-loss-due-to-alzheimer-s-disease
#8
Tonia Munder, Anna Pfeffer, Stefanie Schreyer, Jing Guo, Juergen Braun, Ingolf Sack, Barbara Steiner, Charlotte Klein
PURPOSE: To investigate in vivo viscoelastic parameters related to early histopathological changes in the hippocampus and the cortex in early, preclinical Alzheimer's disease (AD) stages. MATERIALS AND METHODS: Magnetic resonance elastography (MRE) was applied to female APP23 mice, an established transgenic mouse model of AD, at three different stages early in disease progression. To investigate the potential therapeutic effects of physical, cognitive, and social stimulation on brain viscoelasticity and histopathological characteristics, MRE was also applied after exposing young APP23 mice to environmentally enriched cage conditions (ENR), for 1, 12, or 24 weeks, which corresponds to adolescent, young-adult, and adult age at the time of analysis...
April 19, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28422266/transient-elastography-may-improve-detection-of-liver-fibrosis-in-psoriasis-patients-treated-with-methotrexate
#9
Toomas Talme, Pernilla Nikamo, Peter Rosenberg, Mona Ståhle
No abstract text is available yet for this article.
April 19, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28422172/transient-elastography-as-a-screening-tool-for-liver-fibrosis-in-a-large-hemodialysis-population
#10
Ben-Chung Cheng, Yi-Hao Yen, Jung-Fu Chen, Cheng-Kun Wu, Kuo-Chin Chang, Po-Lin Tseng, Ming-Chao Tsai, Ming-Tsung Lin, Jung-Ting Lin, Jin-Bor Chen, Tsung-Hui Hu
Metabolic syndrome, an etiological factor in non-alcoholic fatty liver disease (NAFLD), is often present in hemodialysis patients. Little is known about the prevalence of, and factors associated with, liver fibrosis in hemodialysis populations. We used transient elastography (TE) to investigate these phenomena. 659 patients treated with chronic hemodialysis were enrolled. We excluded those with excess alcohol intake, liver stiffness measurement (LSM) failure, or unreliable LSM values. LSM ≥8.0 kPa was used as a cutoff suggesting clinically relevant fibrosis...
April 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28421905/ultrasonic-elastography-exploration-of-the-foetal-brain-a-case-of-atypical-choroid-plexus-papilloma
#11
Caroline Diguisto, Emmanuel G Simon, Samuel Callé, Redouane Ternifi, Jean-Pierre Remeniéras, Philipe Hervé, Franck Perrotin
No abstract text is available yet for this article.
May 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28419634/contrast-enhanced-ultrasound-and-elastography-imaging-of-the-neonatal-brain-a-review
#12
REVIEW
Christopher Bailey, Thierry A G M Huisman, Robert M de Jong, Misun Hwang
Neonates presenting with neurologic symptoms require rapid, noninvasive imaging with high spatial resolution and tissue contrast. Magnetic resonance imaging (MRI) is currently the most sensitive and specific imaging modality for evaluation of neurological pathology. This modality does come with several challenges in the neonatal population, namely, the need to transport a possibly critically sick neonate to the MRI suite and the necessity of the neonate to remain still for a significant length of time, occasionally requiring sedation...
April 17, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28418825/science-to-practice-quantitative-us-elastography-can-be-used-to-quantify-mechanical-and-histologic-tendon-healing-in-a-rabbit-model-of-achilles-tendon-transection
#13
Kenneth S Lee, Jack Martin, Darryl Thelen
Compression-based ultrasonographic (US) elastography is associated with time-dependent mechanical and histologic changes of the healing tendon in a transected rabbit model of the Achilles tendon. This finding will lead to continued development of quantitative US, which can be used to objectively assess a diseased or healing tendon. With advances in the method used, clinical translation of tendon elastography may enable clinicians to diagnose tendon damage and track healing, which should improve both treatment and outcome...
May 2017: Radiology
https://www.readbyqxmd.com/read/28417472/evaluation-of-liver-kidney-and-spleen-elasticity-in-healthy-newborns-and-infants-using-shear-wave-elastography
#14
Figen Bakirtas Palabiyik, Ercan Inci, Rustu Turkay, Derya Bas
OBJECTIVES: Elasticity measurements of tissues can be valuable in the diagnosis and management of various diseases. The aim of this study was to determine the elasticity values for normal liver, kidney, and spleen of healthy newborns and infants using shear wave elastography (SWE) imaging. METHODS: A total of 50 healthy term newborns and infants (19 girls and 31 boys; mean age 20.1 days, range 1 to 70 days) were examined by an experienced pediatric radiologist using SWE...
April 18, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28416221/ombitasvir-paritaprevir-and-ritonavir-plus-dasabuvir-for-8-weeks-in-previously-untreated-patients-with-hepatitis-c-virus-genotype-1b-infection-without-cirrhosis-garnet-a-single-arm-open-label-phase-3b-trial
#15
Tania M Welzel, Tarik Asselah, Emily O Dumas, Stefan Zeuzem, David Shaw, Rawi Hazzan, Xavier Forns, Tami Pilot-Matias, Wenjing Lu, Daniel E Cohen, Jordan J Feld
BACKGROUND: Clinical studies have shown high rates of sustained virological response (hepatitis C virus [HCV] RNA <15 IU/mL) at post-treatment week 12 (SVR12) in patients with genotype 1b infection with and without cirrhosis who received coformulated ombitasvir, paritaprevir, and ritonavir, plus dasabuvir, without ribavirin, for 12 weeks. In this study, we aimed to assess 8-week treatment with ombitasvir, paritaprevir, and ritonavir, plus dasabuvir, without ribavirin in patients infected with HCV genotype 1b without cirrhosis...
April 13, 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28415898/-31-phosphorus-magnetic-resonance-spectroscopy-of-the-liver-for-evaluating-inflammation-and-fibrosis-in-autoimmune-hepatitis
#16
Lauri Puustinen, Antti Hakkarainen, Reetta Kivisaari, Sonja Boyd, Urpo Nieminen, Martti Färkkilä, Nina Lundbom, Perttu Arkkila
BACKGROUND: Liver biopsy is the gold standard in evaluating inflammation and fibrosis in autoimmune hepatitis. AIMS: In search of non-invasive follow-up tools in autoimmune hepatitis, we evaluated (31)phosphorus magnetic resonance spectroscopy ((31)P MRS). METHODS: Twelve consecutive AIH patients (mean age 42.8 years, 10 women) underwent liver biopsy, routine laboratory liver function tests, which were compared to findings in (31)P MRS and transient elastography (TE)...
April 17, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/28415140/imaging-modalities-for-characterising-focal-pancreatic-lesions
#17
REVIEW
Lawrence Mj Best, Vishal Rawji, Stephen P Pereira, Brian R Davidson, Kurinchi Selvan Gurusamy
BACKGROUND: Increasing numbers of incidental pancreatic lesions are being detected each year. Accurate characterisation of pancreatic lesions into benign, precancerous, and cancer masses is crucial in deciding whether to use treatment or surveillance. Distinguishing benign lesions from precancerous and cancerous lesions can prevent patients from undergoing unnecessary major surgery. Despite the importance of accurately classifying pancreatic lesions, there is no clear algorithm for management of focal pancreatic lesions...
April 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28414822/2-dimensional-shear-wave-elastography-interobserver-agreement-and-factors-related-to-interobserver-discrepancy
#18
Kibo Yoon, Woo Kyoung Jeong, Yongsoo Kim, Min Yeong Kim, Tae Yeob Kim, Joo Hyun Sohn
PURPOSE: To evaluate the interobserver reproducibility of two-dimensional shear wave elastography (2D-SWE) in measuring liver stiffness (LS) and to investigate factors related to liver 2D-SWE. MATERIALS AND METHODS: A prospective study was conducted between August 2011 and August 2012 in rheumatoid arthritis patients who had been treated with methotrexate. Interobserver reproducibility of 2D-SWE was evaluated, and the relationship between interobserver difference in LS and related factors was analyzed using linear regression analyses...
2017: PloS One
https://www.readbyqxmd.com/read/28414057/non-invasive-assessment-of-liver-fibrosis-in-patients-with-hbv-related-chronic-liver-disease-undergoing-antiviral-treatment-a-preliminary-study
#19
Cristina Stasi, Elena Salomoni, Umberto Arena, Giampaolo Corti, Paolo Montalto, Filippo Bartalesi, Fabio Marra, Giacomo Laffi, Stefano Milani, Anna Linda Zignego, Massimo Pinzani
In chronic hepatitis B (CHB) patients, fibrosis assessment during antiviral treatment is a key step in the clinical management. Aim of this study was to evaluate the performance of elastography in assessing fibrosis stage in CHB before and after two years of nucleoside/nucleotide analogues (NUC) treatment in comparison with indirect serum markers. CHB diagnosis was made according to standard criteria. A clinical and virological evaluation was performed at baseline and again at 3, 6, 9, 12 18, and 24 months during treatment...
April 13, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28413350/mechanics-of-ultrasound-elastography
#20
REVIEW
Guo-Yang Li, Yanping Cao
Ultrasound elastography enables in vivo measurement of the mechanical properties of living soft tissues in a non-destructive and non-invasive manner and has attracted considerable interest for clinical use in recent years. Continuum mechanics plays an essential role in understanding and improving ultrasound-based elastography methods and is the main focus of this review. In particular, the mechanics theories involved in both static and dynamic elastography methods are surveyed. They may help understand the challenges in and opportunities for the practical applications of various ultrasound elastography methods to characterize the linear elastic, viscoelastic, anisotropic elastic and hyperelastic properties of both bulk and thin-walled soft materials, especially the in vivo characterization of biological soft tissues...
March 2017: Proceedings. Mathematical, Physical, and Engineering Sciences
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