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https://www.readbyqxmd.com/read/28651307/role-of-shear-wave-elastography-in-evaluating-the-risk-of-hepatocellular-carcinoma-in-patients-with-chronic-hepatitis-b
#1
Jae Yoon Jeong, Joo Hyun Sohn, Won Sohn, Chan Hyuk Park, Tae Yeob Kim, Dae Won Jun, Yongsoo Kim, Woo Kyoung Jeong
Background/Aims: To investigate the use of measurements of liver stiffness (LS) by two-dimensional real-time shear wave elastography (SWE) for predicting the development of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB). Methods: We retrospectively collected data on 291 enrolled patients with CHB whose LS had been measured using SWE. Results: The mean age of the patients was 46.8 years; males predominated (67%), and 40 of the patients (14%) had clinical cirrhosis...
June 27, 2017: Gut and Liver
https://www.readbyqxmd.com/read/28646602/comparison-of-acoustic-radiation-force-impulse-imaging-and-strain-elastography-in-differentiating-malignant-from-benign-thyroid-nodules
#2
Fengjuan Zhang, Xinming Zhao, Ruoling Han, Min Du, Ping Li, Xiaohui Ji
OBJECTIVES: This study aimed to evaluate the diagnostic value of acoustic radiation force impulse (ARFI) imaging and strain elastography in differentiating malignant from benign thyroid nodules. METHODS: This study included 128 patients (104 female and 24 male; mean age ± standard deviation, 48 ± 11 years; range, 23-76 years) with 152 pathologically proven thyroid nodules. Conventional sonography, strain ratio (SR) of strain elastography, virtual touch tissue imaging (VTI) grade, and virtual touch tissue quantification (shear wave velocity [SWV]) from ARFI imaging data were generated for each nodule...
June 24, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28644804/global-time-delay-estimation-in-ultrasound-elastography
#3
Hoda S Hashemi, Hassan Rivaz
A critical step in quasi-static ultrasound elastography is estimation of time-delay between two frames of radiofrequency (RF) data that are obtained while the tissue is undergoing deformation. This paper presents a novel technique for timedelay estimation (TDE) of all samples of RF data simultaneously, thereby exploiting all the information in RF data for TDE. A nonlinear cost function that incorporates similarity of RF data intensity and prior information of displacement continuity is formulated. Optimization of this function involves searching for TDE of all samples of the RF data, rendering the optimization intractable with conventional techniques given that the number of variables can be approximately one million...
June 21, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28643136/assessment-of-liver-fibrosis-in-chronic-hepatitis-comparison-of-shear-wave-elastography-and-transient-elastography
#4
Shashi B Paul, Prasenjit Das, Mousumi Mahanta, Vishnubhatla Sreenivas, Saurabh Kedia, Nancy Kalra, Harpreet Kaur, Maneesh Vijayvargiya, Shouriyo Ghosh, Shivanand R Gamanagatti, Shalimar, Siddhartha Dutta Gupta, Subrat K Acharya
PURPOSE: To evaluate the diagnostic accuracy of shear wave elastography (SWE) and transient elastography (TE) in the evaluation of liver fibrosis in chronic hepatitis B (CHB) and C (CHC) patients taking liver biopsy as gold standard. METHODS: Ethics committee approved this prospective cross-sectional study. Between October 2012 and December 2014, consecutive CHB/CHC patients fulfilling the inclusion criteria were included-age more than 18 years, informed written consent, willing and suitable for liver biopsy...
June 22, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28640694/assessment-of-rectal-tumors-with-shear-wave-elastography-before-surgery-comparison-with-endorectal-us
#5
Li-Da Chen, Wei Wang, Jian-Bo Xu, Jian-Hui Chen, Xin-Hua Zhang, Hui Wu, Jin-Ning Ye, Jin-Ya Liu, Zhi-Qiang Nie, Ming-De Lu, Xiao-Yan Xie
Purpose To compare the value of endorectal ultrasonography (US) with shear-wave elastography (SWE) in staging rectal tumors before surgery. Materials and Methods This prospective study was approved by the institutional review board and written informed consent was obtained. In a pilot cohort from April 2015 to January 2016, 70 patients with rectal adenocarcinomas and/or adenomas confirmed with histopathologic examination underwent both endorectal US and SWE. Tumor stiffness and three regions of reference backgrounds, as well as tumor stiffness ratios (SRs) versus these backgrounds, were analyzed...
June 21, 2017: Radiology
https://www.readbyqxmd.com/read/28640693/evaluation-of-screening-us-detected-breast-masses-by-combined-use-of-elastography-and-color-doppler-us-with-b-mode-us-in-women-with-dense-breasts-a-multicenter-prospective-study
#6
Su Hyun Lee, Jin Chung, Hye Young Choi, Seon Hyeong Choi, Eun Bi Ryu, Kyung Hee Ko, Hye Ryoung Koo, Jeong Seon Park, Ann Yi, Ji Hyun Youk, Eun Ju Son, A Jung Chu, Jung Min Chang, Nariya Cho, Myoung-Jin Jang, Shin Ho Kook, Eun Suk Cha, Woo Kyung Moon
Purpose To investigate the value of the combined use of elastography and color Doppler ultrasonography (US) with B-mode US for evaluation of screening US-detected breast masses in women with dense breasts. Materials and Methods This prospective, multicenter study included asymptomatic women with dense breasts who were referred for screening US between November 2013 and December 2014. Eligible women had a newly detected breast mass at conventional B-mode US screening, for which elastography and color Doppler US were performed...
June 21, 2017: Radiology
https://www.readbyqxmd.com/read/28639927/carotid-artery-plaque-vulnerability-assessment-using-noninvasive-ultrasound-elastography-validation-with-mri
#7
Marie-Hélène Roy Cardinal, Maarten H G Heusinkveld, Zhao Qin, Richard G P Lopata, Cyrille Naim, Gilles Soulez, Guy Cloutier
OBJECTIVE: Vulnerable and nonvulnerable carotid artery plaques have different tissue morphology and composition that may affect plaque biomechanics. The objective of this study is to evaluate plaque vulnerability with the use of ultrasound noninvasive vascular elastography (NIVE). MATERIALS AND METHODS: Thirty-one patients (mean [± SD] age, 69 ± 7 years) with stenosis of the internal carotid artery of 50% or greater were enrolled in this cross-sectional study...
July 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28639099/erratum-to-intravascular-ultrasound-elastography-analysis-of-the-elastic-mechanical-properties-of-atherosclerotic-plaque
#8
Zhaohuan Li, Lin Wang, Xiaobo Hu, Pengfei Zhang, Yifei Chen, Xinxin Liu, Mingjun Xu, Haijun Su, Mei Zhang
No abstract text is available yet for this article.
June 21, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28638943/elevated-serum-heat-shock-protein-70-and-liver-stiffness-reflect-hepatic-dysfunction-and-severity-in-postoperative-biliary-atresia
#9
Sittisak Honsawek, Wanvisa Udomsinprasert, Napaphat Jirathanathornnukul, Voranush Chongsrisawat, Yong Poovorawan
BACKGROUND: Biliary atresia (BA) is a severe chronic liver disease characterized by progressive obstructive cholangiopathy of biliary tract. Heat shock protein 70 (HSP70) is involved in protecting cells against a wide variety of stress and plays a protective role in tissue damage. The purpose of this study was to investigate serum HSP70 and liver stiffness in BA and determine the association of serum HSP70, liver stiffness, and outcome parameters in post-Kasai BA patients. METHODS: One hundred post-Kasai BA patients and 40 controls were enrolled...
June 21, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28634626/hepatic-shear-wave-elastography-in-children-under-free-breathing-and-breath-hold-conditions
#10
Caroline Jung, Michael Groth, Kay Uwe Petersen, Anna Hammel, Florian Brinkert, Enke Grabhorn, Sören Alexander Weidemann, Jasmin Busch, Gerhard Adam, Jochen Herrmann
OBJECTIVES: To compare hepatic 2D shear wave elastography (2D SWE) in children between free-breathing and breath-hold conditions, in terms of measurement agreement and time expenditure. METHODS: A cohort of 57 children (12.7±4.3 years) who underwent standardized 2D SWE between May and October 2015 were retrospectively evaluated. Liver elastograms were obtained under free-breathing and breath-hold conditions and time expenditure was measured. Median stiffness, interquartile range (IQR), and IQR/median ratio were calculated based on 12, six, and three elastograms...
June 20, 2017: European Radiology
https://www.readbyqxmd.com/read/28634041/a-machine-learning-algorithm-toward-color-analysis-for-chronic-liver-disease-classification-employing-ultrasound-shear-wave-elastography
#11
Ilias Gatos, Stavros Tsantis, Stavros Spiliopoulos, Dimitris Karnabatidis, Ioannis Theotokas, Pavlos Zoumpoulis, Thanasis Loupas, John D Hazle, George C Kagadis
The purpose of the present study was to employ a computer-aided diagnosis system that classifies chronic liver disease (CLD) using ultrasound shear wave elastography (SWE) imaging, with a stiffness value-clustering and machine-learning algorithm. A clinical data set of 126 patients (56 healthy controls, 70 with CLD) was analyzed. First, an RGB-to-stiffness inverse mapping technique was employed. A five-cluster segmentation was then performed associating corresponding different-color regions with certain stiffness value ranges acquired from the SWE manufacturer-provided color bar...
June 17, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28629395/early-experiences-from-one-of-the-first-treatment-programs-for-chronic-hepatitis-b-in-sub-saharan-africa
#12
Hanna Aberra, Hailemichael Desalegn, Nega Berhe, Girmay Medhin, Kathrine Stene-Johansen, Svein Gunnar Gundersen, Asgeir Johannessen
BACKGROUND: Treatment for chronic hepatitis B (CHB) is virtually absent in sub-Saharan Africa. Here we present early experiences from a pilot program for treatment of CHB in Ethiopia. METHODS: Adults (≥18 years) with CHB were included in a cohort study at St. Paul's Hospital Millennium Medical College, Addis Ababa, from February 2015. The baseline assessment included liver function tests, viral markers and transient elastography (Fibroscan 402, Echosense, France)...
June 19, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28629386/strain-elastography-imaging-for-early-detection-and-prediction-of-tumor-response-to-concurrent-chemo-radiotherapy-in-locally-advanced-cervical-cancer-feasibility-study
#13
Yan Xu, Lijing Zhu, Baorui Liu, Tong Ru, Huanhuan Wang, Jian He, Song Liu, Xiaofeng Yang, Zhengyang Zhou, Tian Liu
BACKGROUND: To investigate the feasibility of strain elastography imaging in early detecting and predicting treatment response in patients receiving concurrent chemo-radiotherapy (CCRT) for locally advanced cervical cancer. METHODS: Between January 2015 and June 2016, 47 patients with locally advanced cervical cancer were enrolled in a feasibility study approved by the institutional review board. All patients underwent CCRT and received strain elastography examinations at 4 time points: pre-therapy (baseline), 1 week and 2 weeks during, as well as immediately post CCRT...
June 19, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28628420/value-of-multiparametric-us-in-the-assessment-of-intratesticular-lesions
#14
Thomas Auer, Tobias De Zordo, Christian Dejaco, Leonhard Gruber, Renate Pichler, Werner Jaschke, Vikram S Dogra, Friedrich Aigner
Purpose To evaluate the diagnostic accuracy of multiparametric ultrasonography (US) consisting of gray-scale US, color Doppler US, strain elastography, and contrast agent-enhanced US in the assessment of intratesticular lesions. Materials and Methods Institutional review board approval was obtained for this retrospective study. From January 2012 to December 2015, 55 focal testicular lesions that were indeterminate on gray-scale US scans were further characterized with color Doppler US, strain elastography, and contrast-enhanced US...
June 16, 2017: Radiology
https://www.readbyqxmd.com/read/28628033/nonalcoholic-fatty-liver-disease-with-cirrhosis-increases-familial-risk-for-advanced-fibrosis
#15
Cyrielle Caussy, Meera Soni, Jeffrey Cui, Ricki Bettencourt, Nicholas Schork, Chi-Hua Chen, Mahdi Al Ikhwan, Shirin Bassirian, Sandra Cepin, Monica P Gonzalez, Michel Mendler, Yuko Kono, Irine Vodkin, Kristin Mekeel, Jeffrey Haldorson, Alan Hemming, Barbara Andrews, Joanie Salotti, Lisa Richards, David A Brenner, Claude B Sirlin, Rohit Loomba
BACKGROUND: The risk of advanced fibrosis in first-degree relatives of patients with nonalcoholic fatty liver disease and cirrhosis (NAFLD-cirrhosis) is unknown and needs to be systematically quantified. We aimed to prospectively assess the risk of advanced fibrosis in first-degree relatives of probands with NAFLD-cirrhosis. METHODS: This is a cross-sectional analysis of a prospective cohort of 26 probands with NAFLD-cirrhosis and 39 first-degree relatives. The control population included 69 community-dwelling twin, sib-sib, or parent-offspring pairs (n = 138), comprising 69 individuals randomly ascertained to be without evidence of NAFLD and 69 of their first-degree relatives...
June 19, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28624924/evaluation-of-hepatic-fibrosis-a-review-from-the-society-of-abdominal-radiology-disease-focus-panel
#16
REVIEW
Jeanne M Horowitz, Sudhakar K Venkatesh, Richard L Ehman, Kartik Jhaveri, Patrick Kamath, Michael A Ohliger, Anthony E Samir, Alvin C Silva, Bachir Taouli, Michael S Torbenson, Michael L Wells, Benjamin Yeh, Frank H Miller
Hepatic fibrosis is potentially reversible; however early diagnosis is necessary for treatment in order to halt progression to cirrhosis and development of complications including portal hypertension and hepatocellular carcinoma. Morphologic signs of cirrhosis on ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) alone are unreliable and are seen with more advanced disease. Newer imaging techniques to diagnose liver fibrosis are reliable and accurate, and include magnetic resonance elastography and US elastography (one-dimensional transient elastography and point shear wave elastography or acoustic radiation force impulse imaging)...
June 17, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28624301/ultrasound-elastography-with-imaging-overcoming-emerging-technology-reimbursement%C3%A2-challenges
#17
Courtney C Moreno, Nikhar Kinger, Pardeep K Mittal, James Spivey, Deborah A Baumgarten, Richard Duszak
No abstract text is available yet for this article.
June 14, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28622450/large-esophageal-varice-screening-by-a-sequential-algorithm-using-a-cirrhosis-blood-test-and-optionally-capsule-endoscopy
#18
Paul Calès, Sylvie Sacher-Huvelin, Dominique Valla, Christophe Bureau, Anne Olivier, Frédéric Oberti, Jérôme Boursier, Jean Paul Galmiche
BACKGROUND & AIMS: Large esophageal varice (LEV) screening is recommended in cirrhosis. We performed a prospective study to improve non-invasive LEV screening. DESIGN: 287 patients with cirrhosis had upper gastrointestinal endoscopy (LEV reference), esophageal capsule endoscopy (ECE), liver elastography and blood marker analyses. CirrhoMeter (cirrhosis blood test), the most accurate non-invasive LEV test, was segmented for cirrhosis (reference comparator) or LEV...
June 16, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/28618301/noninvasive-measurement-of-wave-speed-of-porcine-cornea-in-ex-vivo-porcine-eyes-for-various-intraocular-pressures
#19
Boran Zhou, Arthur J Sit, Xiaoming Zhang
The objective of this study was to extend an ultrasound surface wave elastography (USWE) technique for noninvasive measurement of ocular tissue elastic properties. In particular, we aim to establish the relationship between the wave speed of cornea and the intraocular pressure (IOP). Normal ranges of IOP are between 12 and 22mmHg. Ex vivo porcine eye balls were used in this research. The porcine eye ball was supported by the gelatin phantom in a testing container. Some water was pour into the container for the ultrasound measurement...
June 7, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28617884/dynamics-of-liver-stiffness-values-by-means-of-transient-elastography-in-patients-with-hcv-liver-cirrhosis-undergoing-interferon-free-treatment
#20
Ioan Sporea, Raluca Lupușoru, Ruxandra Mare, Alina Popescu, Liana Gheorghe, Speranța Iacob, Roxana Șirli
BACKGROUND AND AIMS: Liver stiffness (LS) measurement by Transient Elastography (TE) has been widely accepted as a tool for fibrosis assessment. The aim of this study was to assess LS dynamics in a group of patients with HCV liver cirrhosis after interferon free treatment (IFT). METHODS: This two-center clinical trial included 225 patients with compensated HCV cirrhosis (all genotype 1b), who received IFT for 12 weeks. All patients were evaluated by means of TE at the beginning and at the end of treatment (EOT), and a subgroup (170 patients) also 12 weeks after EOT; all of them had sustained viral response (SVR)...
June 2017: Journal of Gastrointestinal and Liver Diseases: JGLD
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