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Preventive CVD

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https://www.readbyqxmd.com/read/28350711/physical-activity-and-lifetime-risk-of-cardiovascular-disease-and-cancer
#1
Yasuhiko Kubota, Kelly R Evenson, Richard F MacLehose, Nicholas S Roetker, Corinne E Joshu, Aaron R Folsom
PURPOSE: Although the World Health Organization (WHO) has recommended moderate- to vigorous-intensity physical activity (MVPA) to prevent cardiovascular disease (CVD) and some cancers, there are no estimates of lifetime risk of these non-communicable diseases according to PA levels. We aimed to estimate the lifetime risk of CVD and cancers according to PA levels. METHODS: We followed 5,807 men and 7,252 women in the U.S. age 45-64 initially free of CVD and cancer from 1987 through 2012, and used a life table approach to estimate lifetime risks of CVD (coronary heart disease, heart failure and stroke) and total cancer according to PA levels: poor (0 minutes/week of MVPA), intermediate (1-74 minutes/week of VPA or 1-149 minutes/week of MVPA) or recommended (≥75 minutes/week of VPA or ≥150 minutes/week of MVPA)...
March 27, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28346572/effectiveness-of-cardiac-rehabilitation-for-prevention-and-treatment-of-sarcopenia-in-patients-with-cardiovascular-disease-a-retrospective-cross-sectional-analysis
#2
H Harada, H Kai, H Niiyama, Y Nishiyama, A Katoh, N Yoshida, Y Fukumoto, H Ikeda
OBJECTIVE: Sarcopenia is a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength, with the risk of frailty and poor quality of life. This study aimed to clarify the clinical characteristics of sarcopenia and to investigate the effects of comprehensive cardiac rehabilitation (CCR), including nutrition, physical exercise and medication, in patients with cardiovascular disease (CVD). METHODS: We retrospectively studied 322 inpatients with CVD (age 72±12 years)...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28342822/antiplatelet-activity-of-drugs-used-in-hypertension-dyslipidemia-and-diabetes-additional-benefit-in-cardiovascular-diseases-prevention
#3
REVIEW
Cesar Sepúlveda, Iván Palomo, Eduardo Fuentes
Beyond its function in hemostasis, platelets activation has an important role in cardiovascular diseases (CVD) development. There are different clinical conditions that can mediate abnormal platelet activation and favors pathological thrombosis and CVD. These include Hypertension, diabetes and dyslipidemia, all risks factors from CVD development. Different drugs employed in the handled of these conditions have showed decreases platelet activation and related markers. This effect is in part by improved the base condition; however someone of these drugs can modulate platelet targets...
March 22, 2017: Vascular Pharmacology
https://www.readbyqxmd.com/read/28341688/global-cardiovascular-risk-assessment-in-the-primary-prevention-of-cardiovascular-disease-in-adults-systematic-review-of-systematic-reviews
#4
Dylan R J Collins, Alice C Tompson, Igho J Onakpoya, Nia Roberts, Alison M Ward, Carl J Heneghan
OBJECTIVE: To identify, critically appraise and summarise existing systematic reviews on the impact of global cardiovascular risk assessment in the primary prevention of cardiovascular disease (CVD) in adults. DESIGN: Systematic review of systematic reviews published between January 2005 and October 2016 in The Cochrane Library, EMBASE, MEDLINE or CINAHL databases, and post hoc analysis of primary trials. PARTICIPANTS, INTERVENTIONS, OUTCOMES: Systematic reviews of interventions involving global cardiovascular risk assessment relative to no formal risk assessment in adults with no history of CVD...
March 24, 2017: BMJ Open
https://www.readbyqxmd.com/read/28337931/utilizing-nutritional-genomics-to-tailor-diets-for-the-prevention-of-cardiovascular-disease-a-guide-for-upcoming-studies-and-implementations
#5
Dolores Corella, Oscar Coltell, George Mattingley, José V Sorlí, Jose M Ordovas
Personalized diets based on an individual's genome to optimize the success of dietary intervention and reduce genetic cardiovascular disease (CVD) risk, is one of the challenges most frequently discussed in the scientific community. Areas covered: The authors gathered literature-based evidence on nutritional genomics and CVD phenotypes, our own results and research experience to provide a critical overview of the current situation of using nutritional genomics to tailor diets for CVD prevention and to propose guidelines for future studies and implementations...
March 24, 2017: Expert Review of Molecular Diagnostics
https://www.readbyqxmd.com/read/28335423/treatment-with-17%C3%AE-estradiol-reduced-body-weight-and-the-risk-of-cardiovascular-disease-in-a-high-fat-diet-induced-animal-model-of-obesity
#6
Wei-Jen Ting, Chih-Yang Huang, Chong-He Jiang, Yueh-Min Lin, Li-Chin Chung, Chia-Yao Shen, Peiying Pai, Kuan-Ho Lin, Vijaya Padma Viswanadha, Shih-Chieh Liao
Estrogen receptor α (ERα) and estrogen receptor β (ERβ) play important roles in cardiovascular disease (CVD) prevention. Recently, these estrogen receptors were reconsidered as an important treatment target of obesity leading to CVD. In this study, 17β-estradiol (17β-E) replacement therapy applied to high-fat diet-induced obese C57B male mice and ovariectomized (OVX) rats were evaluated, and the protective effects against high-fat diet-induced obesity were assessed in C57B mouse hearts. The results showed that 17β-E treatment activated both ERα and ERβ, and ERβ levels increased in a dose-dependent manner in high-fat diet C57B mouse cardiomyocytes following 17β-E treatment...
March 14, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28332417/cost-effectiveness-of-angiotensin-converting-enzyme-inhibitors-versus-angiotensin-ii-receptor-blockers-as-first-line-treatment-in-autosomal-dominant-polycystic-kidney-disease
#7
L A Clark, S Whitmire, S Patton, C Clark, C M Blanchette, R Howden
INTRODUCTION: Autosomal dominant polycystic kidney disease (ADPKD) is a rare kidney disorder impacting approximately 1:2500 individuals among the general US population. Hypertension is a significant predictor of ADPKD progression and risk factor for development of cardiovascular disease (CVD), the most common cause for mortality among ADPKD patients. Angiotensin-converting enzymes inhibitors (ACE-I) are widely used as first-line treatment in ADPKD for the management of hypertension. However, their cost-effectiveness relative to other hypertensive medications, such as angiotensin II receptor blockers (ARB) has never been assessed...
March 23, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28330394/changes-in-cardiovascular-risk-factors-after-the-great-east-japan-earthquake
#8
Tetsuya Ohira, Hironori Nakano, Masato Nagai, Yui Yumiya, Wen Zhang, Mayu Uemura, Akira Sakai, Shigeatsu Hashimoto
The Great East Japan Earthquake occurred on March 11, 2011, and was followed by a nuclear accident at the Fukushima Daiichi Nuclear Power Plant. The government ordered a mandatory evacuation from the high radioactive concentration area in Fukushima. This evacuation may have forced many evacuees to change specific aspects of their lifestyles such as diet and physical activity, which in turn may lead to future incidence of lifestyle diseases such as cardiovascular diseases (CVDs). To address this concern, the association between the evacuation and changes in CVD risk factors before and after the disaster was examined in the Fukushima Health Management Survey...
March 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28329052/acute-coronary-syndrome-in-women-rising-hospitalizations-in-middle-aged-french-women-2004-14
#9
Amélie Gabet, Nicolas Danchin, Yves Juillière, Valérie Olié
Aims: We aimed to analyse trends in annual incidence of hospitalized acute coronary syndrome (ACS) in France from 2004 to 2014. Methods and results: Primary diagnosis of ACS and subtypes on admissions were selected in national and exhaustive French Hospitalization Database from 2004 to 2014. Age-standardized rates were computed using standardization on the census of the 2010 European population and mean annual percent changes were estimated by using Poisson regression model...
March 11, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28327394/early-identification-of-familial-hypercholesterolaemia-fh-the-prevention-of-cardiovascular-disease-cvd
#10
J Lungley, Z Jayne, D Harvey, D R Nair
No abstract text is available yet for this article.
December 2016: Atherosclerosis
https://www.readbyqxmd.com/read/28326542/current-and-future-therapies-for-addressing-the-effects-of-inflammation-on-hdl-cholesterol-metabolism
#11
REVIEW
Fatima Iqbal, Wendy S Baker, Madiha I Khan, Shwetha Thukuntla, Kevin H McKinney, Nicola Abate, Demidmaa Tuvdendorj
Cardiovascular disease (CVD) is a major cause of morbidity and mortality worldwide. Inflammatory processes arising from metabolic abnormalities are known to precipitate the development of CVD. Several metabolic and inflammatory markers have been proposed for predicting the progression of CVD, including high density lipoprotein cholesterol (HDL-C). For ~50 years, HDL-C has been considered as the atheroprotective 'good' cholesterol because of its strong inverse association with the progression of CVD. Thus, interventions to increase the concentration of HDL-C have been successfully tested in animals; however, clinical trials were unable to confirm the cardiovascular benefits of pharmaceutical interventions aimed at increasing HDL-C levels...
March 22, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28322884/cardiovascular-disease-screening-in-general-practice-general-practitioner-recording-of-common-risk-factors
#12
Lyle R Turner, Flavia Cicuttini, Christopher Pearce, Danielle Mazza
The assessment and screening of individual risk factors for cardiovascular disease (CVD) is a critical component of CVD prevention strategies in general practice (GP). This study sought to examine current CVD risk factor recording as recommended by Australian guidelines for the management of absolute cardiovascular disease risk. A retrospective analysis of routine GP data from 149,306 GP patients aged 45years and above in eastern Melbourne was conducted. Data were collected from GP clinics located throughout inner east Melbourne from July 2011 to September 2014 through the Melbourne East Monash General Practice Database...
March 16, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28321266/setting-priorities-to-address-cardiovascular-diseases-through-universal-health-coverage-in-low-and-middle-income-countries
#13
REVIEW
David A Watkins, Rachel A Nugent
Over the past decade, universal health coverage (UHC) has emerged as a major policy goal for many low- and middle-income country governments. Yet, despite the high burden of cardiovascular diseases (CVD), relatively little is known about how to address CVD through UHC. This review covers three major topics. First, we define UHC and provide some context for its importance, and then we illustrate its relevance to CVD prevention and treatment. Second, we discuss how countries might select high-priority CVD interventions for a UHC health benefits package drawing on economic evaluation methods...
2017: Heart Asia
https://www.readbyqxmd.com/read/28320000/guideline-the-uspstf-recommends-low-to-moderate-dose-statins-to-prevent-cvd-in-selected-adults-40-to-75-years-of-age
#14
Neha J Pagidipati, Christopher B Granger
No abstract text is available yet for this article.
March 21, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28317481/gut-microbiota-a-new-marker-of-cardiovascular-disease
#15
Antonio Garcia-Rios, Jose David Torres-Peña, Francisco Perez-Jimenez, Pablo Perez-Martinez
Cardiovascular disease (CVD) continues to be the major cause of death in the developed countries. Moreover, the cardiovascular risk factors leading towards the development of CVD, mainly type 2 diabetes and obesity, are on the rise. The current preventive and therapeutic management, centred on the control of traditional risk factors, is clearly not enough to stop this pandemic. Therefore, the search for new biomarkers in CVD is a priority in most clinical research programs. Currently, interest in gut microbiota has peaked due to its association with cardiovascular and non-cardiovascular diseases...
March 17, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28302025/the-use-of-plant-sterols-and-stanols-as-lipid-lowering-agents-in-cardiovascular-disease
#16
Jacek Rysz, Beata Franczyk, Robert Olszewski, Maciej Banach, Anna Gluba-Brzózka
BACKGROUND: The prevalence of premature atherosclerosis and cardiovascular disease (CVD) is constantly increasing worldwide. It has been proved that LDL-cholesterol (LDL-C) plays causal role in the development of coronary atherosclerosis. The fact that atherosclerosis is a chronic and progressive disease which onsets during the first three decades of life bores questions what to do to maintain LDL-C at low levels throughout life and thus to delay and/or prevent the progress this disease...
March 16, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28301692/vitamin-c-supplementation-for-the-primary-prevention-of-cardiovascular-disease
#17
REVIEW
Lena Al-Khudairy, Nadine Flowers, Rebecca Wheelhouse, Obadah Ghannam, Louise Hartley, Saverio Stranges, Karen Rees
BACKGROUND: Vitamin C is an essential micronutrient and powerful antioxidant. Observational studies have shown an inverse relationship between vitamin C intake and major cardiovascular events and cardiovascular disease (CVD) risk factors. Results from clinical trials are less consistent. OBJECTIVES: To determine the effectiveness of vitamin C supplementation as a single supplement for the primary prevention of CVD. SEARCH METHODS: We searched the following electronic databases on 11 May 2016: the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library; MEDLINE (Ovid); Embase Classic and Embase (Ovid); Web of Science Core Collection (Thomson Reuters); Database of Abstracts of Reviews of Effects (DARE); Health Technology Assessment Database and Health Economics Evaluations Database in the Cochrane Library...
March 16, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28295377/time-restricted-feeding-for-prevention-and-treatment-of-cardiometabolic-disorders
#18
Girish C Melkani, Satchidananda Panda
The soaring prevalence of obesity and diabetes is associated with an increase in comorbidities, including elevated risk for cardiovascular diseases (CVD). CVDs continue to be among the leading causes of death and disability in the United States. While increased nutrition intake from an energy dense diet is known to disrupt metabolic homeostasis and contributes to the disease risk, circadian rhythm disruption is emerging as a new risk factor for CVD. Circadian rhythms coordinate cardiovascular health via temporal control of organismal metabolism and physiology...
March 10, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28292692/using-critical-flicker-frequency-in-the-evaluation-of-visual-impairment-in-preeclamptic-women
#19
Marina Maier, Andreas Brückmann, Ekkehard Schleußner, Dietmar Schlembach
OBJECTIVE: To assess critical flicker frequency (CFF) in normal uneventful pregnancy and preeclampsia. STUDY-DESIGN: Case-control observational study at the University Hospital Jena and Outpatient Institute for Prenatal Diagnosis and Preventive Medicine. 25 non-pregnant women, 75 uncomplicated pregnant women in first, second and third trimester, and 15 women with overt preeclampsia. For comparison with preeclamptic patients we matched 15 normal pregnant women (mNP) for age, parity, body mass index, current smoking and family history of cardiovascular disease (CVD)...
March 1, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28290805/-the-prediction-model-of-cardiovascular-events-among-the-russian-population-methodological-aspects
#20
A V Kontsevaya, S A Shalnova, E I Suvorova, Y A Balanova, S E Evstifeeva, A E Imaeva, A V Kapustina, A D Deev, Y A Karpov, O D Ostroumova, F T Ageev, O S Blinkov, I Yu Zinchuk, K A Repekto, A Boytsov S
Modeling is the common approach for predicting not only the population health, but also the social and economic burden of disease, which is an important argument while making decisions in health care and prevention. AIM: To develop the model for predicting cardiovascular risk, applicable for the assessment of clinical and socio-economic effects of preventive and therapeutic actions at the level of the whole population or part (region, city, group of patients). MATERIAL AND METHODS: An analytical model for making decision was performed by using a Markov model consisting of Markov states and probabilities of transition from one state to another within a certain time interval...
December 2016: Kardiologiia
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