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Preventive CVD

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https://www.readbyqxmd.com/read/29141072/association-of-cetp-gene-variants-with-risk-for-vascular-and-nonvascular-diseases-among-chinese-adults
#1
Iona Y Millwood, Derrick A Bennett, Michael V Holmes, Ruth Boxall, Yu Guo, Zheng Bian, Ling Yang, Sam Sansome, Yiping Chen, Huaidong Du, Canqing Yu, Alex Hacker, Dermot F Reilly, Yunlong Tan, Michael R Hill, Junshi Chen, Richard Peto, Hongbing Shen, Rory Collins, Robert Clarke, Liming Li, Robin G Walters, Zhengming Chen
Importance: Increasing levels of high-density lipoprotein (HDL) cholesterol through pharmacologic inhibition of cholesteryl ester transfer protein (CETP) is a potentially important strategy for prevention and treatment of cardiovascular disease (CVD). Objective: To use genetic variants in the CETP gene to assess potential risks and benefits of lifelong lower CETP activity on CVD and other outcomes. Design, Setting, and Participants: This prospective biobank study included 151 217 individuals aged 30 to 79 years who were enrolled from 5 urban and 5 rural areas of China from June 25, 2004, through July 15, 2008...
November 15, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29140556/withdrawn-transcendental-meditation-for-the-primary-prevention-of-cardiovascular-disease
#2
REVIEW
Louise Hartley, Angelique Mavrodaris, Nadine Flowers, Edzard Ernst, Karen Rees
BACKGROUND: A major determinant in cardiovascular disease (CVD) is stress. As transcendental meditation (TM) is thought to help in lowering negative stress indicators, it may be a beneficial strategy for the primary prevention of CVD. OBJECTIVES: To determine the effectiveness of TM for the primary prevention of CVD. SEARCH METHODS: We searched the following electronic databases: the Cochrane Central Register of Controlled Trials (CENTRAL) (2013, Issue 10); MEDLINE (Ovid) (1946 to week three November 2013); EMBASE Classic and EMBASE (Ovid) (1947 to week 48 2013); ISI Web of Science (1970 to 28 November 2013); and Database of Abstracts of Reviews of Effects (DARE) and Health Technology Assessment Database and Health Economics Evaluations Database (November 2013)...
November 15, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29138274/five-year-effectiveness-of-the-multidisciplinary-risk-assessment-and-management-program-for-primary-care-patients-with-type-2-diabetes-mellitus%C3%A2-ramp-dm-on-dm-related-complications-and-health-service-uses-a-population-based-and-propensity-matched-cohort-study
#3
Eric Yuk Fai Wan, Colman Siu Cheung Fung, Fang Fang Jiao, Esther Yee Tak Yu, Weng Yee Chin, Daniel Yee Tak Fong, Carlos King Ho Wong, Anca Ka Chun Chan, Karina Hiu Yen Chan, Ruby Lai Ping Kwok, Cindy Lo Kuen Lam
OBJECTIVE: To evaluate the 5-year effectiveness of a multidisciplinary Risk Assessment and Management Program for primary care patients with type 2 Diabetes Mellitus (RAMP-DM)‎. RESEARCH DESIGN AND METHODS: A 5-year prospective cohort study was conducted with 121,584 Chinese primary care patients with type 2 DM who were recruited between August 2009 and June 2011. Missing data were dealt with multiple imputations. After excluding patients with prior DM-related complications and one-to-one propensity score matching on all patient characteristics, 26,718 RAMP-DM participants and 26,718 matched usual-care patients were followed up for a median time of 4...
November 14, 2017: Diabetes Care
https://www.readbyqxmd.com/read/29138175/statin-prescribing-trends-for-primary-and-secondary-prevention-of-cardiovascular-disease
#4
Felicity Brown, Alexander Singer, Alan Katz, Gerald Konrad
OBJECTIVE: To determine the proportion of patients receiving statins for primary or secondary prevention of cardiovascular disease (CVD), as well as to describe lipid-screening trends. DESIGN: Retrospective chart review using the Manitoba Primary Care Research Network repository. SETTING: Manitoba. PARTICIPANTS: A total of 149 262 patients. MAIN OUTCOME MEASURES: Proportion of patients who were taking statins for primary or secondary prevention of cardiovascular disease (CVD), who did not have evidence of CVD recorded in their charts, and who underwent lipid screening; distribution of statins among age groups; and the proportion of patients eligible for lipid screening when the age cutoffs of the 2012 and 2016 Canadian Cardiovascular Society guidelines were applied...
November 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29137666/utilization-of-the-behavior-change-wheel-framework-to-develop-a-model-to-improve-cardiometabolic-screening-for-people-with-severe-mental-illness
#5
Christina Mangurian, Grace C Niu, Dean Schillinger, John W Newcomer, James Dilley, Margaret A Handley
BACKGROUND: Individuals with severe mental illness (e.g., schizophrenia, bipolar disorder) die 10-25 years earlier than the general population, primarily from premature cardiovascular disease (CVD). Contributing factors are complex, but include systemic-related factors of poorly integrated primary care and mental health services. Although evidence-based models exist for integrating mental health care into primary care settings, the evidence base for integrating medical care into specialty mental health settings is limited...
November 14, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/29135691/control-of-intestinal-lipoprotein-secretion-by-dietary-carbohydrates
#6
Priska Stahel, Changting Xiao, Gary F Lewis
PURPOSE OF REVIEW: Dyslipidemia is a major risk factor for atherosclerotic cardiovascular disease (CVD). Lipoproteins secreted by the intestine can contribute to dyslipidemia and may increase risk for CVD. This review focuses on how dietary carbohydrates can impact the production of chylomicrons, thereby influencing plasma concentrations of triglycerides and lipoproteins. RECENT FINDINGS: Hypercaloric diets high in monosaccharides can exacerbate postprandial triglyceride concentration...
November 11, 2017: Current Opinion in Lipidology
https://www.readbyqxmd.com/read/29133599/potential-u-s-population-impact-of-the-2017-american-college-of-cardiology-american-heart-association-high-blood-pressure-guideline
#7
Paul Muntner, Robert M Carey, Samuel Gidding, Daniel W Jones, Sandra J Taler, Jackson T Wright, Paul K Whelton
Background -The 2017 American College of Cardiology/American Heart Association (ACC/AHA) Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults provides recommendations for the definition of hypertension, systolic and diastolic blood pressure (BP) thresholds for initiation of antihypertensive medication and BP target goals. The objective of this study was to determine the prevalence of hypertension, implications of recommendations for antihypertensive medication and prevalence of BP above the treatment goal among US adults using criteria from the 2017 ACC/AHA and the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC7) guidelines...
November 13, 2017: Circulation
https://www.readbyqxmd.com/read/29131895/association-of-blood-pressure-lowering-with-mortality-and-cardiovascular-disease-across-blood-pressure-levels-a-systematic-review-and-meta-analysis
#8
Mattias Brunström, Bo Carlberg
Importance: High blood pressure (BP) is the most important risk factor for death and cardiovascular disease (CVD) worldwide. The optimal cutoff for treatment of high BP is debated. Objective: To assess the association between BP lowering treatment and death and CVD at different BP levels. Data Sources: Previous systematic reviews were identified from PubMed, the Cochrane Database of Systematic Reviews, and the Database of Abstracts of Reviews of Effect...
November 13, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29130714/intake-of-fibers-and-its-association-with-cardiometabolic-risk-factors-in-individuals-on-a-secondary-prevention-for-cardiovascular-diseases-a-multicenter-study
#9
Luciana Pereira Pinto Dias, Simone Raimondi de Souza, Viviane Sahade, Nayra Anielly Cabral Cantanhede, José Albuquerque De Figueiredo Neto, Bernadete Weber
INTRODUCTION: Among the non-pharmacologic measures for the prevention and treatment of cardiovascular diseases (CVD), which are the first cause of death worldwide, the adequate intake of dietary fibers (DF) has shown an important role. OBJECTIVE: To evaluate the association between the intake of DF and the cardio-metabolic risk factors in individuals on a secondary prevention for CVD. METHODS: Transversal study with basal data of the study's DICA Br participants belonging to collaborative centers in the states of Maranhão (MA), Bahia (BA) and Rio de Janeiro (RJ)...
October 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29124386/olive-oil-consumption-and-10-year-2002-2012-cardiovascular-disease-incidence-the-attica-study
#10
Georgia-Maria Kouli, Demosthenes B Panagiotakos, Ioannis Kyrou, Emanuela Magriplis, Ekavi N Georgousopoulou, Christina Chrysohoou, Constantine Tsigos, Dimitrios Tousoulis, Christos Pitsavos
PURPOSE: Olive oil, being rich in mono-unsaturated fatty acids and anti-inflammatory compounds, may have protective effects against cardiovascular disease (CVD). The aim of the present work was to examine the association of olive oil consumption with the 10-year CVD incidence in adults without pre-existing CVD. METHODS: The ATTICA Study is a prospective, population-based study conducted in the greater metropolitan area of Athens (Attica, Greece). During 2001-2002, 3042 CVD-free adults (1514 men and 1528 women) were voluntarily recruited to the ATTICA study...
November 9, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/29119482/patterns-of-comorbidity-and-disease-characteristics-among-patients-with-ankylosing-spondylitis-a-cross-sectional-study
#11
Lotta Ljung, Björn Sundström, Johan Smeds, Maria Ketonen, Helena Forsblad-d'Elia
The knowledge of the development of comorbidities in patients with ankylosing spondylitis (AS) is limited. The aim of this study was to analyse associations between AS disease characteristics and comorbidity and to evaluate patterns of comorbidities in patients with AS. Patients with AS, fulfilling the modified New York Criteria, were identified (n = 346, mean age 56 ± 15 years, 75% men, 99% HLA B27 positive). Through a review of the patient records, data on disease activity parameters, laboratory results, disease manifestations, and diagnoses of any clinically significant comorbidity was obtained...
November 8, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/29118949/cardiovascular-disease-events-and-its-predictors-in-women-isfahan-cohort-study-ics
#12
Masoumeh Sadeghi, Azam Soleimani, Hamidreza Roohafza, Safoura Yazdekhasti, Shahram Oveisgharan, Mohammad Talaei, Nizal Sarrafzadegan
Introduction: As a lack of validated data about cardiovascular (CV) events and its risk factors (RFs) in women of Eastern Mediterranean region, we aimed to evaluate common predictors of CV events among Iranian women. Methods: Isfahan cohort study (ICS) is a prospective cohort that followed 6323 residents (51.3% women, aged 35-75 years) from three counties and their rural districts in central Iran. Common cardiovascular disease (CVD) RFs namely hypertension (HTN), diabetes mellitus, dyslipidemia, abdominal obesity, smoking, low apolipoproteins A ( apo-A) and high apolipoprotein B (apo-B) were evaluated...
2017: Journal of Cardiovascular and Thoracic Research
https://www.readbyqxmd.com/read/29117723/cardiovascular-disease-risk-predicts-health-perception-in-prison-inmates
#13
Zyad T Saleh, Alison Connell, Terry A Lennie, Alison L Bailey, Rami A Elshatarat, Khalil Yousef, Debra K Moser
We hypothesized that risk factors for cardiovascular disease (CVD) would be associated with worse health perceptions in prison inmates. This study included 362 inmates recruited from four medium security prisons in Kentucky. Framingham Risk Score was used to estimate the risk of developing CVD within the next 10 years. A single item on self-rated health from the Medical Outcomes Survey-Short Form 36 was used to measure health perception. Multinomial logistic regression showed that for every 1-unit increase in Framingham Risk Score, inmates were 23% more likely to have rated their health as fair/poor and 11% more likely to rate their health as good rather than very good/excellent...
November 1, 2017: Clinical Nursing Research
https://www.readbyqxmd.com/read/29117624/the-role-of-lipids-in-the-pathogenesis-of-metabolic-syndrome-in-adolescents
#14
Shahnaz Taghizadeh, Mohammad Alizadeh
The increasing prevalence of childhood obesity is a driving force behind the increase in adolescent's metabolic syndrome (MetS). Although there is no clear consensus about the pediatric definition for MetS, this syndrome is becoming very common among adolescents. It is characterized by insulin resistance (IR), dyslipidemia, abdominal obesity and hypertension, and is associated with a high risk of type 2 diabetes mellitus and CVD in adulthood. Due to the increasing prevalence of obesity, there is strong incentive to reduce the impact of the adverse health effects associated with MetS...
November 8, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/29117146/transferability-of-the-mediterranean-diet-to-non-mediterranean-countries-what-is-and-what-is-not-the-mediterranean-diet
#15
Miguel Ángel Martínez-González, Maria Soledad Hershey, Itziar Zazpe, Antonia Trichopoulou
Substantial evidence has verified the Mediterranean diet's (MedDiet) nutritional adequacy, long-term sustainability, and effectiveness for preventing hard clinical events from cardiovascular disease (CVD), as well as increasing longevity. This article includes a cumulative meta-analysis of prospective studies supporting a strong inverse association between closer adherence to the MedDiet and the incidence of hard clinical events of CVD. The MedDiet has become an increasingly popular topic of interest when focusing on overall food patterns rather than single nutrient intake, not only in Mediterranean countries, but also globally...
November 8, 2017: Nutrients
https://www.readbyqxmd.com/read/29114197/low-levels-of-vitamin-d-an-emerging-risk-for-cardiovascular-diseases-a-review
#16
REVIEW
Farrukh Majeed
Sunlight is regarded among greatest gifts that are presented in abundance to the human beings from the God. Sunlight is also a rich source of Vitamin D (Vit D) that prevents us from numerous ailments such as autoimmune disorders, various types of cancer, and the above all cardiovascular diseases (CVD). Evident from recent research that Vit D deficiency may be the cause for hypertension, cardiac autonomic imbalance, vascular endothelial dysfunction, metabolic syndrome, and even diabetes. Concurrently, many studies present research outcomes that are contradictory to earlier results and also raised a concern not for general public but also among their treating physicians...
November 2017: International Journal of Health Sciences
https://www.readbyqxmd.com/read/29112241/periodontal-therapy-for-the-management-of-cardiovascular-disease-in-patients-with-chronic-periodontitis
#17
REVIEW
Chunjie Li, Zongkai Lv, Zongdao Shi, Ye Zhu, Yafei Wu, Longjiang Li, Zipporah Iheozor-Ejiofor
BACKGROUND: There is an association between chronic periodontitis and cardiovascular disease (CVD). However, it is not known whether periodontal therapy could prevent or manage CVD in patients with chronic periodontitis. OBJECTIVES: The objective of this systematic review was to investigate the effects of periodontal therapy in preventing the occurrence of, and management or recurrence of, CVD in patients with chronic periodontitis. SEARCH METHODS: Cochrane Oral Health's Information Specialist searched the following databases: Cochrane Oral Health's Trials Register (to 31 August 2017), the Cochrane Central Register of Controlled Trials (CENTRAL) (the Cochrane Library, 2017, Issue 7), MEDLINE Ovid (1946 to 31 August 2017), Embase Ovid (1980 to 31 August 2017) and the Cumulative Index to Nursing and Allied Health Literature (CINAHL EBSCO) (1937 to 31 August 2017) ...
November 7, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29111648/shape-uniform-high-quality-monolayer-mos2-crystals-for-gate-tuneable-photoluminescence
#18
Xiumei Zhang, Haiyan Nan, Shaoqing Xiao, Xi Wan, Zhenhua Ni, Xiaofeng Gu, Kostya Ken Ostrikov
Two-dimensional molybdenum disulfide (MoS2) has recently drawn great attention due to its promising applications in electronics and optoelectronics. Chemical vapor deposition (CVD) is a scalable method to produce large-area MoS2 monolayers, yet it is challenging to achieve shape-uniform, high-quality monolayer MoS2 grains as random, diverse crystallographic orientations and various shapes are produced in the same CVD process. Here we report the growth of high-quality MoS2 monolayers with uniform trianglular shapes dominating (up to 89%) over other shapes on both SiO2/Si and sapphire substrates...
November 7, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29110223/the-effectiveness-and-cost-effectiveness-of-plant-sterol-or-stanol-enriched-functional-foods-as-a-primary-prevention-strategy-for-people-with-cardiovascular-disease-risk-in-england-a-modeling-study
#19
Wei Yang, Heather Gage, Daniel Jackson, Monique Raats
This study appraises the effectiveness and cost-effectiveness of consumption of plant sterol-enriched margarine-type spreads for the prevention of cardiovascular disease (CVD) in people with hypercholesterolemia in England, compared to a normal diet. A nested Markov model was employed using the perspective of the British National Health Service (NHS). Effectiveness outcomes were the 10-year CVD risk of individuals with mild (4-6 mmol/l) and high (above 6 mmol/l) cholesterol by gender and age groups (45-54, 55-64, 65-74, 75-85 years); CVD events avoided and QALY gains over 20 years...
November 6, 2017: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/29105492/real-world-cardiovascular-disease-burden-in-patients-with-atherosclerotic-cardiovascular-disease-a-comprehensive-systematic-literature-review
#20
Dasha Cherepanov, Tanya Bentley, Wendy Hsiao, Pin Xiang, Frank O'Neill, Yi Qian, Nicole Yurgin, David Beenhouwer
OBJECTIVE: Based on randomized controlled trials (RCT), non-fatal myocardial infarction (MI) rates range between 9-15 events per 1,000 person-year, ischemic stroke between 4-6 per 1,000 person-year, CHD death rates between 5-7 events per 1,000 person-year, any major vascular event between 28-53 per 1,000 person-year in patients with atherosclerotic cardiovascular disease (ASCVD). We reviewed global literature on the topic to determine if the real-world burden of secondary major adverse cardiovascular events (MACEs) is higher among ASCVD patients...
November 5, 2017: Current Medical Research and Opinion
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