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Preventive CVD

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https://www.readbyqxmd.com/read/28646635/postprandial-endotoxemia-a-significant-contributor-to-chronic-diseases
#1
Andrew W Campbell
The increase of chronic diseases in the world's population continues unabated. Cardiovascular disease (CVD), type 2 diabetes (T2D), obesity, arthritis, autoimmunity, and gastrointestinal disorders are all too common and costly, and most have as their source inflammation. T2D is now considered a pandemic, and there is one commonality to many of these: They are, for the most part, preventable.
May 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28645496/determining-the-best-percent-predicted-equation-for-estimated-vo2-peak-by-a-1-km-moderate-perceptually-regulated-treadmill-walk-to-predict-mortality-in-outpatients-with-cardiovascular-disease
#2
Giovanni Grazzi, Gianni Mazzoni, Jonathan Myers, Luciano Codecà, Giovanni Pasanisi, Simona Mandini, Massimo Piepoli, Stefano Volpato, Francesco Conconi, Giorgio Chiaranda
OBJECTIVES: To determine the prognostic ability of established percent-predicted equations of peak oxygen consumption (%PRED) estimated by a moderate submaximal walking test in a large cohort of outpatients with cardiovascular disease (CVD). DESIGN: Population-based prospective study. METHODS: A total of 1442 male patients aged 25-85 years at baseline, underwent a moderate perceptually-regulated (11-13 on the 6-20 Borg scale) treadmill walk (1k-TWT) for peak oxygen consumption estimation (VO2 peak)...
June 8, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28645222/dietary-fat-and-risk-of-cardiovascular-disease-recent-controversies-and-advances
#3
Dong D Wang, Frank B Hu
Health effects of dietary fats have been extensively studied for decades. However, controversies exist on the effects of various types of fatty acids, especially saturated fatty acid (SFA), on cardiovascular disease (CVD). Current evidence supports that different types of dietary fatty acids have divergent effects on CVD risk, and the effects also depend strongly on the comparison or replacement macronutrient. A significant reduction in CVD risk can be achieved if SFAs are replaced by unsaturated fats, especially polyunsaturated fatty acids...
June 23, 2017: Annual Review of Nutrition
https://www.readbyqxmd.com/read/28644038/critical-review-on-the-analytical-techniques-for-the-determination-of-the-oldest-statin-atorvastatin-in-bulk-pharmaceutical-formulations-and-biological-fluids
#4
K S Kokilambigai, R Seetharaman, K S Lakshmi
Statins are a group of medicines that can help to lower the level of low-density-lipoprotein(LDL) cholesterol "bad cholesterol" in the blood. Having a high level of LDL cholesterol is potentially dangerous, as it can lead to a hardening and narrowing of arteries (atherosclerosis) and cardiovascular disease (CVD), Atorvastatin is one of the oldest member of the statin family and is used in the treatment of dyslipidemia and the prevention of cardiovascular disease. Atorvastatin was first made in August 1985 and from 1996 to 2012 under the trade name Lipitor, atorvastatin became the world's best selling drug...
June 23, 2017: Critical Reviews in Analytical Chemistry
https://www.readbyqxmd.com/read/28640965/atypical-depression-and-double-depression-predict-new-onset-cardiovascular-disease-in-u-s-adults
#5
Stephanie M Case, Manisha Sawhney, Jesse C Stewart
BACKGROUND: Although depression is a risk factor for cardiovascular disease (CVD), it is unknown whether this risk varies across depressive disorder subtypes. Thus, we investigated atypical major depressive disorder (MDD) and double depression as predictors of new-onset CVD in a nationally representative sample of U.S. adults. METHODS: Prospective data from 28,726 adults initially free of CVD who participated in Wave 1 (2001-2002) and Wave 2 (2004-2005) of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) were examined...
June 22, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28640118/high-normotension-is-associated-with-future-metabolic-syndrome-but-not-cardiovascular-disease-a-10-year-longitudinal-study
#6
Yen-Lin Chen, Chun-Hsien Hsu, Chang-Hsun Hsieh, Chung-Ze Wu, Jiunn-Diann Lin, Jin-Biou Chang, Yao-Jen Liang, Yi-Ting Tsai, Te-Lin Hsia, Dee Pei
Hypertension and prehypertension can increase the risk of developing cardiovascular disease (CVD) and diabetes. However, whether the harmful effects of high blood pressure (BP) are also seen with high normotension remains unknown. This 10-year longitudinal follow-up study aimed to investigate the relationships among normal-range BP, metabolic syndrome (MetS), and CVD.A total of 9133 nonmedicated normotensive participants, 4634 males and 4499 females, aged 60 years or older were enrolled in a standard health examination program at 2 academic hospitals and a health screening center in Taiwan...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28639974/an-evaluation-of-cardioprevent-a-technology-enabled-health-behavior-change-program-for-the-global-reduction-of-cardiovascular-risk
#7
Stephanie A Prince, Robert D Reid, Andrew L Pipe, Lisa A McDonnell
PURPOSE OF REVIEW: Cardiovascular diseases (CVDs) are the leading cause of mortality globally. Primary CVD prevention programs have the potential to improve risk factor profiles and, ultimately, the risk of developing CVD. The present study presents an evaluation of CardioPrevent, a global cardiovascular risk reduction program. RECENT FINDINGS: Of the 478 participants enrolled in the CardioPrevent program, 308 and 236 had complete 6-month and 12-month data, respectively at the time of evaluation...
July 20, 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/28631259/preventive-healthcare-and-health-promotion-in-local-governments-based-on-the-example-of-health-policy-programmes-concerned-with-cardiovascular-diseases-implemented-in-poland-in-2009-2014
#8
Anna Augustynowicz, Aleksandra Czerw, Mariola Kowalska, Krzysztof Bobiński, Adam Fronczak
BACKGROUND: Cardiovascular diseases (CVD) are the cause of over 4.3 million deaths in the World Health Organisation European Region and around 1.9 million deaths in the European Union member states alone. They are also the number-one cause of death in Poland. In 2010 CVDs accounted for 46% of all deaths, and in 2013 - 45.8%. AIM: The aim of the study was to evaluate the performance of the tasks of local government units in the area of preventive healthcare and health promotion on the basis of health policy programmes concerning CVD...
2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28630692/liver-fat-a-relevant-target-for-dietary-intervention-summary-of-a-unilever-workshop
#9
REVIEW
Harry P F Peters, Patrick Schrauwen, Petra Verhoef, Christopher D Byrne, David J Mela, Andreas F H Pfeiffer, Ulf Risérus, Frits R Rosendaal, Vera Schrauwen-Hinderling
Currently it is estimated that about 1 billion people globally have non-alcoholic fatty liver disease (NAFLD), a condition in which liver fat exceeds 5 % of liver weight in the absence of significant alcohol intake. Due to the central role of the liver in metabolism, the prevalence of NAFLD is increasing in parallel with the prevalence of obesity, insulin resistance and other risk factors of metabolic diseases. However, the contribution of liver fat to the risk of type 2 diabetes mellitus and CVD, relative to other ectopic fat depots and to other risk markers, is unclear...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/28626088/secondary-prevention-of-cardiovascular-disease-in-patients-with-type-2-diabetes-international-insights-from-the-tecos-trial
#10
Neha J Pagidipati, Ann Marie Navar, Karen S Pieper, Jennifer B Green, M Angelyn Bethel, Paul W Armstrong, Robert G Josse, Darren K McGuire, Yuliya Lokhnygina, Jan H Cornel, Sigrun Halvorsen, Timo E Strandberg, Tuncay Delibasi, Rury R Holman, Eric D Peterson
Background -Intensive risk factor modification significantly improves outcomes for patients with diabetes and cardiovascular disease (CVD). However, the degree to which secondary prevention treatment goals are achieved in international clinical practice is unknown. Methods -Attainment of 5 secondary prevention parameters-aspirin use, lipid control (low-density lipoprotein cholesterol <70 mg/dL or statin therapy), blood pressure control (<140 mmHg systolic, <90 mmHg diastolic), angiotensin-converting enzyme inhibitor or angiotensin receptor blocker use, and non-smoking status-was evaluated among 13,616 patients from 38 countries with diabetes and known CVD at entry into TECOS...
June 16, 2017: Circulation
https://www.readbyqxmd.com/read/28625611/comparing-sf-36%C3%A2-scores-versus-biomarkers-to-predict-mortality-in-primary-cardiac-prevention-patients
#11
EDITORIAL
Rony Lahoud, Vasutakarn Chongthammakun, Yuping Wu, Nael Hawwa, Danielle M Brennan, Leslie Cho
BACKGROUND: Risk stratification plays an important role in evaluating patients with no known cardiovascular disease (CVD). Few studies have investigated health-related quality of life questionnaires such as the Medical Outcomes Study Short Form-36 (SF-36®) as predictive tools for mortality, particularly in direct comparison with biomarkers. Our objective is to measure the relative effectiveness of SF-36® scores in predicting mortality when compared to traditional and novel biomarkers in a primary prevention population...
June 15, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28624099/cardiovascular-disease-and-cancer-evidence-for-shared-disease-pathways-and-pharmacologic-prevention
#12
REVIEW
Farzad Masoudkabir, Nizal Sarrafzadegan, Carolyn Gotay, Andrew Ignaszewski, Andrew D Krahn, Margot K Davis, Christopher Franco, Arya Mani
Cardiovascular disease (CVD) and cancer are leading causes of mortality and morbidity worldwide. Strategies to improve their treatment and prevention are global priorities and major focus of World Health Organization's joint prevention programs. Emerging evidence suggests that modifiable risk factors including diet, sedentary lifestyle, obesity and tobacco use are central to the pathogenesis of both diseases and are reflected in common genetic, cellular, and signaling mechanisms. Understanding this important biological overlap is critical and may help identify novel therapeutic and preventative strategies for both disorders...
June 2, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28623035/prevalence-and-risk-factors-associated-to-peripheral-arterial-disease-in-an-adult-population-from-colombia
#13
Lorena Urbano, Eliana Portilla, Wilson Muñoz, Albert Hofman, Carlos H Sierra-Torres
BACKGROUND: Cardiovascular diseases (CVD) are the most important cause of mortality in Latin America while peripheral arterial disease (PAD) is the third leading cause of atherosclerotic cardiovascular morbidity. OBJECTIVE: To establish the prevalence of PAD and the distribution of traditional CVD risk factors in a population from the Department of Cauca, Colombia. METHODS: A cross-sectional study was performed in a total of 10,000 subjects aged ≥40 years from 36 municipalities...
June 13, 2017: Archivos de Cardiología de México
https://www.readbyqxmd.com/read/28622958/metabolic-syndrome-in-long-term-survivors-of-hematopoietic-stem-cell-transplantation
#14
REVIEW
Sophie C Ragbourne, Martin A Crook
Since its introduction more than 50 years ago, hematopoietic stem-cell transplantation (HSCT) has transformed from an inescapably fatal procedure to one where cure from malignant and other nonmalignant hematologic diseases is becoming increasingly common. Nevertheless, longevity is not entirely restored. New causes of mortality have emerged; of particular importance is that of increased cardiovascular disease (CVD), related to metabolic syndrome and its components. Controversy exists over whether the metabolic abnormalities induced are a direct effect of HSCT itself or a consequence of other therapies involved...
June 2017: Clinical Lymphoma, Myeloma & Leukemia
https://www.readbyqxmd.com/read/28622736/vaxchora-a-single-dose-oral-cholera-vaccine
#15
Adriana Cabrera, Jayne E Lepage, Karyn M Sullivan, Sheila M Seed
OBJECTIVE: To review trials evaluating the efficacy and safety of Vaxchora, a reformulated, single-dose, oral, lyophilized Vibrio cholerae CVD 103-HgR vaccine for the prevention of travel-related cholera caused by V cholerae serogroup O1. DATA SOURCES: A literature search was conducted using MEDLINE (1946 to January week 3, 2017) and EMBASE (1996 to 2017 week 3). Keywords included oral cholera vaccine, single-dose, Vaxchora, and CVD 103-HgR. Limits included human, clinical trials published in English since 2010...
July 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/28620646/kidney-transplant-recipients-perspectives-on-cardiovascular-disease-and-related-risk-factors-after-transplantation-a-qualitative-study
#16
Fabián Ballesteros, Julie Allard, Céline Durand, Héloïse Cardinal, Lyne Lalonde, Marie-Chantal Fortin
BACKGROUND: Cardiovascular disease (CVD) is a major cause of mortality among kidney transplant recipients (KTRs). These patients have a high prevalence of risk factors, such as hypertension, diabetes, and dyslipidemia. Despite regular medical care, few of them reach the recommended therapeutic targets. The objective of this study is to describe KTRs' perspectives on CVD and related risk factors, as well as their priorities for posttransplant care. METHODS: Twenty-six KTRs participated in a semistructured interview about their personal experience and offered their perspectives on CVD risk factors posttransplant...
June 2017: Transplantation Direct
https://www.readbyqxmd.com/read/28620111/dietary-fats-and-cardiovascular-disease-a-presidential-advisory-from-the-american-heart-association
#17
REVIEW
Frank M Sacks, Alice H Lichtenstein, Jason H Y Wu, Lawrence J Appel, Mark A Creager, Penny M Kris-Etherton, Michael Miller, Eric B Rimm, Lawrence L Rudel, Jennifer G Robinson, Neil J Stone, Linda V Van Horn
Cardiovascular disease (CVD) is the leading global cause of death, accounting for 17.3 million deaths per year. Preventive treatment that reduces CVD by even a small percentage can substantially reduce, nationally and globally, the number of people who develop CVD and the costs of caring for them. This American Heart Association presidential advisory on dietary fats and CVD reviews and discusses the scientific evidence, including the most recent studies, on the effects of dietary saturated fat intake and its replacement by other types of fats and carbohydrates on CVD...
June 15, 2017: Circulation
https://www.readbyqxmd.com/read/28619779/multiple-health-behaviour-change-interventions-for-primary-prevention-of-cardiovascular-disease-in-primary-care-systematic-review-and-meta-analysis
#18
Samah Alageel, Martin C Gulliford, Lisa McDermott, Alison J Wright
BACKGROUND: It is uncertain whether multiple health behaviour change (MHBC) interventions are effective for the primary prevention of cardiovascular disease (CVD) in primary care. A systematic review and a meta-analysis were performed to evaluate the effectiveness of MHBC interventions on CVD risk and CVD risk factors; the study also evaluated associations of theoretical frameworks and intervention components with intervention effectiveness. METHODS: The search included randomised controlled trials of MHBC interventions aimed at reducing CVD risk in primary prevention population up to 2017...
June 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28619115/effectiveness-of-a-physical-activity-program-on-cardiovascular-disease-risk-in-adult-primary-health-care-users-the-pas-a-pas-community-intervention-trial
#19
Victoria Arija, Felipe Villalobos, Roser Pedret, Angels Vinuesa, Mercé Timón, Teresa Basora, Dolors Aguas, Josep Basora
BACKGROUND: Physical activity is a major, modifiable, risk factor for cardiovascular disease (CVD) that contributes to the prevention and management of CVD. The aim of this study was to assess the short- and medium-term effectiveness of 9 months of a supervised physical activity program, including sociocultural activities, on CVD risk in adults. METHODS: Multicentered, randomized, controlled community intervention involving 364 patients in four primary care centers...
June 15, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28618906/quality-assurance-and-the-need-to-evaluate-interventions-and-audit-programme-outcomes
#20
Min Zhao, Ilonca Vaartjes, Kerstin Klipstein-Grobusch, Kornelia Kotseva, Catriona Jennings, Diederick E Grobbee, Ian Graham
Evidence-based clinical guidelines provide standards for the provision of healthcare. However, these guidelines have been poorly implemented in daily practice. Clinical audit is a quality improvement tool to promote quality of care in daily practice and to improve outcomes through the systematic review of care delivery and implementation of changes. A major priority in the management of subjects with cardiovascular disease (CVD) management is secondary prevention by controlling cardiovascular risk factors and providing appropriate medical treatment...
June 2017: European Journal of Preventive Cardiology
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