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https://www.readbyqxmd.com/read/29156994/experimental-diabetes-impairs-maternal-reproductive-performance-in-pregnant-wistar-rats-and-their-offspring
#1
Leticia Bequer, Tahiry Gómez, José L Molina, Alain Álvarez, Claudia Chaviano, Sonia Clapés
The aim of this study was to determine the effect of mild hyperglycemia on metabolism during pregnancy, the maternal reproductive performance, and the characteristics of the offspring in neonatal mild diabetic-induced Wistar rats. The experimental diabetes model was generated by neonatal streptozotocin administration (100 mg of streptozotocin/Kg bw/sc) in female Wistar rats. At adulthood, the control and diabetic group were mated. At the 20th day of gestation, a maternal and fetal blood sample were collected for biochemical measurement...
November 20, 2017: Systems Biology in Reproductive Medicine
https://www.readbyqxmd.com/read/29075630/laparoscopic-adnexectomy-for-ovarian-torsion-during-late-pregnancy-case-report-of-a-non-conservative-treatment-and-literature-analysis
#2
Jean Bouquet de Joliniere, J B Dubuisson, F Khomsi, A Fadhlaoui, G Grant, N Ben Ali, A Major, A Feki
Diagnosis of adnexial torsion is difficult during pregancy (1). The time of decision and laparoscopy is that of the risk of necrosis of the adnexa and, therefore, of the ovarian prognosis. The loss of an ovary can compromise the following fertility. Even if concerns related to laparoscopy in pregnant patients include a limited surgical field, with a risk of uterine injury and negative fetal effects of CO2 insufflation. Evidence base suggests that minimally invasive surgery can be safe and better than laparotomy for management of adnexal masses during late pregnancy with good postoperative and obstetric outcomes...
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/29020788/-complete-molar-pregancy-with-development-of-non-metastatic-persistent-trophoblastic-diseasea-case-report-reflection-of-rules-of-care-and-decision-making-processes-forensic-responsibility-and-the-position-of-doctor-in-the-general-gynecologic-and-obstetric-outpatient
#3
S Zeman, P Trávník, K Dvořáková, J Zemanová
OBJECTIVE: To define the forensic responsibility and the position of doctor in the general gynecologic and obstetric outpatient practice in care of the complete molar pregancy. DESIGN: Case report and review article. SETTING: General gynecologic and obstetric outpatient practice Velké Meziříčí; Sanatorium REPROMEDA, Centre of reproductive medicine and preimplantation genetics, Brno; Histopatology department of Hospital Jihlava. CASE REPORT: The changing clinical presentation of complete molar pregnancy with development of non-metastatic gestational trophoblastic disease: management...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/29017023/maternal-iron-nutriture-as-a-critical-modulator-of-fasd-risk-in-alcohol-exposed-pregnancies
#4
Kaylee K Helfrich, Nipun Saini, Pamela J Kling, Susan M Smith
Alcohol consumption during pregnancy places the fetus at risk for permanent physical, cognitive, and behavioral impairments, collectively termed fetal alcohol spectrum disorders (FASD). However, prenatal alcohol exposure (PAE) outcomes vary widely, and growing evidence suggests that maternal nutrition is a modifying factor. Certain nutrients, such as iron, may modulate FASD outcomes. Untreated gestational iron deficiency (ID) causes persistent neurodevelopmental deficits in the offspring that affect many of the same domains damaged by PAE...
October 10, 2017: Biochemistry and Cell Biology, Biochimie et Biologie Cellulaire
https://www.readbyqxmd.com/read/28877634/certolizumab-an-anti-tnf-safe-during-pregancy-the-crib-study-results-an-interview-with-professor-xavier-mariette
#5
Xavier Mariette
Professor Xavier Mariette, MD, PhD, has served as the Head of the Rheumatology Department of Bicêtre Hospital, Paris-Sud University since 1999, a role he took following 10 years of practice of clinical immunology. Professor Mariette has initiated a number of clinical research studies on biotherapies in autoimmune diseases. He is the head of the French RATIO (Research Axed on Tolerance of Biotherapy) observatory, collecting specific rare serious adverse events in patients treated with anti-TNF. He initiated the French AIR (Autoimmunity and Rituximab) and ORA (Orencia and Rheumatoid arthritis) registries of patients with autoimmune diseases treated with rituximab and abatacept...
September 2017: Immunotherapy
https://www.readbyqxmd.com/read/28466503/gingival-enlargement-in-a-pregnant-woman-with-acute-monocytic-leukaemia-a-case-report
#6
Y-W Fu, H-Z Xu
The objective of the present study was to report the case of a pregnant woman with severe gingival enlargement for 3 months with undiagnosed acute leukaemia. The pregnant woman presented with anaemia and generalized gingival enlargement. A provisional diagnosis of gingival enlargement in pregnancy was made. Twelve days after the initial treatment, the patient was referred and admitted to the haematology department of a local hospital with clinical signs of anaemia and thrombocytopenia. Blood count showed a white blood cell count of 9...
May 3, 2017: Australian Dental Journal
https://www.readbyqxmd.com/read/28342949/use-of-thiopurines-during-conception-and-pregnancy-is-not-associated-with-adverse-pregnancy-outcomes-or-health-of-infants-at-one-year-in-a-prospective-study
#7
Shannon L Kanis, Alison de Lima-Karagiannis, Nanne K H de Boer, C Janneke van der Woude
BACKGROUND & AIMS: Most data on the safety of thiopurine therapy for inflammatory bowel disease (IBD) during pregnancy come from retrospective studies, which makes it difficult to adjust for confounding factors. We performed a prospective cohort study to determine whether thiopurine use affects pregnancy outcomes or health outcomes of children. METHODS: We performed a prospective study of all women who visited the IBD preconception outpatient clinic at our tertiary health center in The Netherlands from December 2008 through May 2016...
March 22, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28300898/pruritic-folliculitis-of-pregnancy
#8
Lilian Mathias Delorenze, Letícia Guedes Branco, Luiza Fiszon Cerqueira, Wellington Batista Vasques, Simone de Abreu Neves Salles, Enoi Guedes Vilar
Pruritic folliculitis of pregnancy is a rare disease of unknown etiology. It occcurs primarily during pregnancy, usually with spontaneous resolution postpartum. It is characterized by a benign dermatosis, with papular and pustular follicular lesions that first appear on the torso and occasionally spread throughout the body. We report the case of a patient in the 27th week of pregnancy, with a two-month evolution of pruritic and papular erythematous lesions on her lower back. Differential diagnosis includes other pregnancy-specific dermatoses: gestational pemphigoid, pruritic urticarial papules and plaques of pregnancy (PUPPP), prurigo of pregnancy, and (PUPPP) and prurigo of pregancy...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28228338/extra-and-intracellular-calcium-signaling-pathway-s-differentially-regulate-histamine-induced-myometrial-contractions-during-early-and-mid-pregnancy-stages-in-buffaloes-bubalus-bubalis
#9
Abhishek Sharma, Udayraj P Nakade, Soumen Choudhury, Rajkumar Singh Yadav, Satish Kumar Garg
This study examines the differential role of calcium signaling pathway(s) in histamine-induced uterotonic action during early and mid-pregnancy stages in buffaloes. Compared to mid pregnancy, tonic contraction, amplitude and mean-integral tension were significantly increased by histamine to produce myometrial contraction during early pregnancy with small effects on phasic contraction and frequency. Although uterotonic action of histamine during both stages of pregnancy is sensitive to nifedipine (a L-type Ca(2+) channels blocker) and NNC55-0396 (T-type Ca(2+) channels blocker), the role of extracellular calcium seems to be more significant during mid-pregnancy as in this stage histamine produced only 9...
April 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28095282/active-smoking-and-associated-behavioural-risk-factors-before-and-during-pregnancy-prevalence-and-attitudes-among-newborns-mothers-in-mures-county-romania
#10
Florina Ruta, Calin Avram, Septimiu Voidăzan, Claudiu Mărginean, Vladimir Bacârea, Zoltán Ábrám, Kristie Foley, Andrea Fogarasi-Grenczer, Melinda Pénzes, Monica Tarcea
BACKGROUND AND AIM: Smoking before, during and after pregnancy leads to detrimental outcomes on maternal and foetal health and represents an important public health issue. This study aims to evaluate the prevalence and correlates of smoking before and during pregnancy in a sample of Romanian women. METHODS: A cross-sectional survey was conducted among mothers (N=1,278) in three maternity hospitals in Tirgu-Mures, Romania, immediately after childbirth, in 2014. We evaluated the prevalence of smoking before and during pregnancy and used binary logistic regression to assess the influence of socio-demographics and other health behaviour factors in three groups of women: non-smoking pregnant women, women who continued smoking during pregnancy, and smokers who quit during pregnancy...
December 2016: Central European Journal of Public Health
https://www.readbyqxmd.com/read/27077456/thiol-disulphide-homeostasis-in-pregnant-women-with-familial-mediterranean-fever
#11
Aykan Yucel, Cem Yasar Sanhal, Korkut Daglar, Ozgur Kara, Dilek Uygur, Ozcan Erel
OBJECTIVE: To investigate the presence of oxidative stress (OS) in pregnant women with Familial Mediterranean fever (FMF) in the first trimester by evaluating thiol/disulphide homeostasis. STUDY DESIGN: A total of 31 pregnant women with a diagnosis of FMF, between 11(0) and 13(6) weeks of gestation, were compared with 51 healthy pregnant controls at the same gestational weeks. A recently defined method was used to measure plasma native thiol, total thiol and disulphide levels...
November 2016: Redox Report: Communications in Free Radical Research
https://www.readbyqxmd.com/read/27062799/-follow-up-study-in-traditional-chinese-medicine-of-reinforcing-kidney-and-resolving-stasis-and-thinking-of-improving-women-s-ability-of-high-quality-fertility-and-pregnancy
#12
Kun Ma, Min Li
High quality of fertility and pregancy is a specific presentation of family planning in this new historic environment. Our country adopted two-child policy from November, 2013. This symbolized an adjustive stage of reproduction policy in 21st century. It is a major adjustment in the development of national population. As a contry of tremendous population, it is very important to have a high- quality fertility and pregancy for the future of the whole nation, which would improve population quality and restrict development of population...
October 2015: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/27055233/different-intensities-of-glycaemic-control-for-women-with-gestational-diabetes-mellitus
#13
REVIEW
Ruth Martis, Julie Brown, Jane Alsweiler, Tineke J Crawford, Caroline A Crowther
BACKGROUND: Gestational diabetes mellitus (GDM) has major short- and long-term implications for both the mother and her baby. GDM is defined as a carbohydrate intolerance resulting in hyperglycaemia or any degree of glucose intolerance with onset or first recognition during pregnancy from 24 weeks' gestation onwards and which resolves following the birth of the baby. Rates for GDM can be as high as 25% depending on the population and diagnostic criteria used and rates are increasing globally...
April 7, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26336784/empowering-embodiment-through-belly-dancin-in-pregancy-a-phenomenological-exploration
#14
Imogen Jackson
Exercise during pregnancy has physical benefits for mother and fetus; however there has been little research into potential emotional benefits. At least 10-15 per cent of mothers suffer from ante- and postnatal depression, which can lead to extreme adverse consequences. This has been linked to self esteem, body image and isolation, amongst other factors. Belly dance has been shown to increase self esteem and body image and to provide a sense of community in non-pregnant women. This study uses phenomenology to explore how pregnant women experience belly dance using semi-structured interviews with two mothers...
May 2015: Practising Midwife
https://www.readbyqxmd.com/read/26288149/modifying-the-luteal-phase-support-in-natural-cycle-frozen-thawed-embryo-transfer-improves-cycle-outcome
#15
COMPARATIVE STUDY
Jigal Haas, Daniel Lantsberg, Noa Feldman, Daphna Manela, Ronit Machtinger, Shir Dar, Jaron Rabinovici, Raoul Orvieto
With the recent trend toward single embryo transfer (ET), cryopreservation of extraneous embryos is becoming increasingly prevalent. Several replacement protocols for frozen-thawed ET (FET) exist, with no advantage of one protocol over the others. All consecutive patients undergoing natural cycle Day-3 FET cycles between May 2012 and March 2015 in our IVF unit were evaluated. While following spontaneous ovulation, all patients received progesterone luteal support. Since June 2014, patients underwent the same aforementioned natural cycle FET cycles, with two additional injections, one of recombinant hCG (250 mcg) and the other of GnRH-agonist (triptorelin 0...
2015: Gynecological Endocrinology
https://www.readbyqxmd.com/read/26114001/gonococcal-chorioamnionitis-with-antepartum-fetal-death-in-utero
#16
B Coutanceau, J Boujenah, C Poncelet
We report the case of a patient who developed gonococcal chorioamnionitis resulting in stillbirth at 28 + 4 weeks of pregancy. As this infection is rare and potentially serious, questions remain regarding occurrence and screening for Neisseria gonorrhoeae infection.
2015: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/25987000/current-pregnancy-among-women-with-spinal-cord-injury-findings-from-the-us-national-spinal-cord-injury-database
#17
L I Iezzoni, Y Chen, A B J McLain
STUDY DESIGN: Cross-sectional study. OBJECTIVES: To examine the prevalence of pregnancy and associations with sociodemographic and clinical factors among women with spinal cord injury (SCI). SETTING: US National Spinal Cord Injury Database, an SCI registry that interviews participants 1, 5 and then every 5 years post injury. Data include SCI clinical details, functional impairments, participation measures, depressive symptoms and life satisfaction...
November 2015: Spinal Cord
https://www.readbyqxmd.com/read/25986676/deletion-of-the-serotonin-receptor-type-3a-in-mice-leads-to-sudden-cardiac-death-during-pregnancy
#18
Hyewon Park, Chang-Myung Oh, Junbeom Park, Hyelim Park, Shanyu Cui, Hyung Suk Kim, Jun Namkung, Sang-kyu Park, Hui-Nam Pak, Moon-Hyoung Lee, Hail Kim, Boyoung Joung
BACKGROUND: The serotonin receptor type 3 (Htr3) blocker is associated with QT prolongation and torsades de pointes. However, little is known about effects of Htr3 on the heart arrhythmia. METHODS AND RESULTS: An electrophysiological study Involving knock-out (KO) female mice lacking functional Htr3a (Htr3a(-/-)) and their wild-type littermates during non-pregancy (NP) and late pregnancy (LP) was performed. Htr3a mRNA was present in the wild-type, but not in the Htr3a(-/-)mouse hearts...
2015: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/25574996/identification-of-risk-factors-for-cesarean-delivery-following-induction-of-labour
#19
P Rijal
BACKGROUND: Induction of labor is one of the most common procedures in obstetrics. Induction has been found to both increase and decrease the risk of cesarean delivery. Various studies have found different factors in different studies. The purpose of this study is to increase our knowledge of factors that increase risk of cesarean delivery when labour is induced at term. METHODS: A prospective observational study was conducted from June 2006-July 2007 at an obstetric unit of Eastern Nepal...
May 2014: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/25510034/-tocolysis-with-nifedipin-its-use-in-current-practice
#20
V Karamisheva, S Ivanov, D Jordanova, B Marinov, G Dimitrov, A Nachev
AIM: The aim of the study is to establish the safety and efficacy of calcium channel blocker- Nifedipin as tocolytic agents. A wide range of tocolytics have been utilized for the management of preterm labor Calcium channel blockers, namely nifedipine, gained popularity as tocolytics due to the oral route of administration, availability of immediate- and slow-release preparations, the low incidence of maternal adverse effects associated with their use, and the fact that they are inexpensive...
2014: Akusherstvo i Ginekologii︠a︡
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