keyword
MENU ▼
Read by QxMD icon Read
search

Motor cortex plasticity

keyword
https://www.readbyqxmd.com/read/28077329/body-schema-plasticity-after-stroke-subjective-and-neurophysiological-correlates-of-the-rubber-hand-illusion
#1
Roberto Llorens, Adrián Borrego, Priscila Palomo, Ausiàs Cebolla, Enrique Noé, Sergi Bermúdez I Badia, Rosa Baños
Stroke can lead to motor impairments that can affect the body structure and restraint mobility. We hypothesize that brain lesions and their motor sequelae can distort the body schema, a sensorimotor map of body parts and elements in the peripersonal space through which human beings embody the reachable space and ready the body for forthcoming movements. Two main constructs have been identified in the embodiment mechanism: body-ownership, the sense that the body that one inhabits is his/her own, and agency, the sense that one can move and control his/her body...
January 8, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28072803/neural-correlates-of-maladaptive-pain-behavior-in-chronic-neck-pain-a-single-case-control-fmri-study
#2
Konstantin Beinert, Audrey Mouthon, Martin Keller, Michael Mouthon, Jean-Marie Annoni, Wolfgang Taube
Chronic neck pain patients display functional impairments like decreased range of motion, decreased strength, and reduced sensorimotor function. In patients without structural damage, the reason for the persistence of pain is not well understood. Therefore, it is assumed that in chronic pain states, memory processes play an important role. We have now detected and tested a patient that might help us to better understand the neural correlates of maladaptive pain expectation/memory. This patient displays chronic neck pain and restricted unilateral motion of the cervical spine to the left...
January 2017: Pain Physician
https://www.readbyqxmd.com/read/28064022/stimulus-uncertainty-enhances-long-term-potentiation-like-plasticity-in-human-motor-cortex
#3
Martin V Sale, Abbey S Nydam, Jason B Mattingley
Plasticity can be induced in human cortex using paired associative stimulation (PAS), which repeatedly and predictably pairs a peripheral electrical stimulus with transcranial magnetic stimulation (TMS) to the contralateral motor region. Many studies have reported small or inconsistent effects of PAS. Given that uncertain stimuli can promote learning, the predictable nature of the stimulation in conventional PAS paradigms might serve to attenuate plasticity induction. Here, we introduced stimulus uncertainty into the PAS paradigm to investigate if it can boost plasticity induction...
December 18, 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28063106/excitability-of-the-motor-cortex-in-patients-with-migraine-changes-with-the-time-elapsed-from-the-last-attack
#4
Francesca Cortese, Gianluca Coppola, Davide Di Lenola, Mariano Serrao, Cherubino Di Lorenzo, Vincenzo Parisi, Francesco Pierelli
BACKGROUND: Motor-evoked potentials (MEPs) produced by single-pulse transcranial magnetic stimulation (TMS) of the motor cortex can be an objective measure of cortical excitability. Previously, MEP thresholds were found to be normal, increased, or even reduced in patients with migraine. In the present study, we determined whether the level of cortical excitability changes with the time interval from the last migraine attack, thereby accounting for the inconsistencies in previous reports...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28033506/preconditioning-tdcs-facilitates-subsequent-tdcs-effect-on-skill-acquisition-in-older-adults
#5
Hakuei Fujiyama, Mark R Hinder, Azadeh Barzideh, Charis Van de Vijver, Andreea C Badache, Maria Nathalya Manrique-C, Paola Reissig, Xue Zhang, Oron Levin, Jeffery J Summers, Stephan P Swinnen
Functional motor declines that often occur with advancing age-including reduced efficacy to learn new skills-can have a substantial impact on the quality of life. Recent studies using noninvasive brain stimulation indicate that priming the corticospinal system by lowering the threshold for the induction of long-term potentiation-like plasticity before skill training may facilitate subsequent skill learning. Here, we used "priming" protocol, in which we used transcranial direct current stimulation (tDCS) applying the cathode over the primary motor cortex (M1) before the anode placed over M1 during unimanual isometric force control training (FORCEtraining)...
December 1, 2016: Neurobiology of Aging
https://www.readbyqxmd.com/read/28031148/reliability-and-minimal-detectable-change-of-transcranial-magnetic-stimulation-outcomes-in-healthy-adults-a-systematic-review
#6
REVIEW
Louis-David Beaulieu, Véronique H Flamand, Hugo Massé-Alarie, Cyril Schneider
BACKGROUND: Transcranial magnetic stimulation (TMS) is used worldwide for noninvasively testing human motor systems but its psychometric properties remain unclear. OBJECTIVE/HYPOTHESIS: This work systematically reviewed studies on the reliability of TMS outcome measures of primary motor cortex (M1) excitability in healthy humans, with an emphasis on retrieving minimal detectable changes (MDC). METHODS: The literature search was performed in three databases (Pubmed, CINAHL, Embase) up to June 2016 and additional studies were identified through hand-searching...
December 19, 2016: Brain Stimulation
https://www.readbyqxmd.com/read/28005989/action-video-game-playing-is-reflected-in-enhanced-visuomotor-performance-and-increased-corticospinal-excitability
#7
Olivier Morin-Moncet, Jean-Marc Therrien-Blanchet, Marie C Ferland, Hugo Théoret, Greg L West
Action video game playing is associated with improved visuomotor performance; however, the underlying neural mechanisms associated with this increased performance are not well understood. Using the Serial Reaction Time Task in conjunction with Transcranial Magnetic Stimulation, we investigated if improved visuomotor performance displayed in action video game players (actionVGPs) was associated with increased corticospinal plasticity in primary motor cortex (M1) compared to non-video game players (nonVGPs). Further, we assessed if actionVGPs and nonVGPs displayed differences in procedural motor learning as measured by the SRTT...
2016: PloS One
https://www.readbyqxmd.com/read/28003105/motor-cortex-plasticity-can-indicate-vulnerability-to-motor-fluctuation-and-high-l-dopa-need-in-drug-na%C3%A3-ve-parkinson-s-disease
#8
Asha Kishore, Praveen James, Syam Krishnan, Lydia Yahia-Cherif, Sabine Meunier, Traian Popa
INTRODUCTION: Motor cortex plasticity is reported to be decreased in Parkinson's disease in studies which pooled patients in various stages of the disease. Whether the early decrease in plasticity is related to the motor signs or is linked to the future development of motor complications of treatment is unclear. The aim of the study was to test if motor cortex plasticity and its cerebellar modulation are impaired in treatment-naïve Parkinson's disease, are related to the motor signs of the disease and predict occurrence of motor complications of treatment...
December 13, 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/27992103/resting-state-functional-connectivity-measures-correlate-with-the-response-to-anodal-transcranial-direct-current-stimulation
#9
Brenton Hordacre, Bahar Moezzi, Mitchell R Goldsworthy, Nigel C Rogasch, Lynton J Graetz, Michael C Ridding
Responses to non-invasive brain stimulation are highly variable between subjects. Resting state functional connectivity was investigated as a marker of plasticity induced by anodal transcranial direct current stimulation (tDCS). Twenty-six healthy adults (15 male, 26.4±6.5 years) were tested. Experiment 1 investigated whether functional connectivity could predict modulation of corticospinal excitability following anodal tDCS. Experiment 2 determined test-retest reliability of connectivity measures. Three minutes of electroencephalography was recorded and connectivity was quantified with the debiased weighted phase lag index...
December 19, 2016: European Journal of Neuroscience
https://www.readbyqxmd.com/read/27984200/multi-system-state-shifts-and-cognitive-deficits-induced-by-chronic-morphine-during-abstinence
#10
Haichen Niu, Guanqun Zhang, Haiying Li, Qiang Zhang, Tongzhou Li, Sheng Ding, Lei Wang, Zhonghai Zhang, Yuehua Qiao, Min Hu
Chronic morphine administration induces neural plasticity followed by withdraw. And clinic observation indicates that obvious cognitive deficits are found during withdrawal. However, current neural substrates that regulate dysfunction in withdrawal are unknown. In our studies, chronic morphine administration was used to induce the spontaneous withdrawal model in rats. A series of cognitive abilities was tested to explore brain function. To further evaluate the neural substrates of dysfunction, Manganese-enhanced MRI(MEMRI) was used to map the dysfunctional regions in vivo...
October 28, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27982220/amblyopia-neural-basis-and-therapeutic-approaches
#11
Caio César Peixoto Bretas, Renato Nery Soriano
Abnormalities in visual processing caused by visual deprivation or abnormal binocular interaction may induce amblyopia, which is characterized by reduced visual acuity. Occlusion therapy, the conventional treatment, requires special attention as occlusion of the fellow normal eye may reduce its visual acuity and impair binocular vision. Besides recovering visual acuity, some researchers have recommended restoration of stereoacuity and motor fusion and reverse suppression in order to prevent diplopia. Recent studies have documented that the amblyopic visual cortex has a normal complement of cells but reduced spatial resolution and a disordered topographical map...
September 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/27956400/complement-peptide-c3a-stimulates-neural-plasticity-after-experimental-brain-ischaemia
#12
Anna Stokowska, Alison L Atkins, Javier Morán, Tulen Pekny, Linda Bulmer, Michaela C Pascoe, Scott R Barnum, Rick A Wetsel, Jonas A Nilsson, Mike Dragunow, Marcela Pekna
Ischaemic stroke induces endogenous repair processes that include proliferation and differentiation of neural stem cells and extensive rewiring of the remaining neural connections, yet about 50% of stroke survivors live with severe long-term disability. There is an unmet need for drug therapies to improve recovery by promoting brain plasticity in the subacute to chronic phase after ischaemic stroke. We previously showed that complement-derived peptide C3a regulates neural progenitor cell migration and differentiation in vitro and that C3a receptor signalling stimulates neurogenesis in unchallenged adult mice...
December 12, 2016: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/27955948/array-focal-cortical-stimulation-enhances-motor-function-recovery-and-brain-remodeling-in-a-rat-model-of-ischemia
#13
Jing Yang, Lu Liu, Tao Li, Chengyan Li
OBJECTIVE: Using a new microelectrode array implanted into the cranial window employing a new stimulation protocol, we investigated the effects of the implanted electrode arrays on both motor map plasticity and neural regeneration in a rodent model of stroke. MATERIALS AND METHODS: Rats were pretrained on single-pellet retrieval task, then received focal ischemic infarction and microelectrode arrays implantation. Rats in the cortical stimulation (CS) group received daily electrical stimulation (1 hour each day) for 14 days whereas animals in the no stimulation (NS) group did not receive electrical stimulation and only underwent motor mapping...
December 9, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27939980/corticospinal-circuit-plasticity-in-motor-rehabilitation-from-spinal-cord-injury
#14
REVIEW
Najet Serradj, Sydney F Agger, Edmund R Hollis
Restoring corticospinal function after spinal cord injury is a significant challenge as the corticospinal tract elicits no substantive, spontaneous regeneration, and its interruption leaves a permanent deficit. The corticospinal circuit serves multiple motor and sensory functions within the mammalian nervous system as the direct link between isocortex and spinal cord. Maturation of the corticospinal circuit involves the refinement of projections within the spinal cord and a subsequent refinement of motor maps within the cortex...
December 6, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27927951/effects-of-the-selective-%C3%AE-5-gabaar-antagonist-s44819-on-excitability-in-the-human-brain-a-tms-emg-and-tms-eeg-phase-i-study
#15
Ghazaleh Darmani, Carl M Zipser, Gabriele M Böhmer, Karine Deschet, Florian Müller-Dahlhaus, Paolo Belardinelli, Matthias Schwab, Ulf Ziemann
: Alpha-5 gamma-aminobutyric acid type A receptors (α5-GABAARs) are located extrasynaptically, regulate neuronal excitability through tonic inhibition, and are fundamentally important for processes such as plasticity and learning. For example, pharmacological blockade of α5-GABAAR in mice with ischemic stroke improved recovery of function by normalizing exaggerated perilesional α5-GABAAR-dependent tonic inhibition. S44819 is a novel competitive selective antagonist of the α5-GABAAR at the GABA-binding site...
December 7, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27925214/acute-and-chronic-effects-of-noradrenergic-enhancement-on-transcranial-direct-current-stimulation-induced-neuroplasticity-in-humans
#16
Hsiao-I Kuo, Walter Paulus, Giorgi Batsikadze, Asif Jamil, Min-Fang Kuo, Michael A Nitsche
KEY POINTS: Chronic administration of the selective noradrenaline reuptake inhibitor (NRI) reboxetine (RBX) increased and prolonged the long-term potentiation-like plasticity induced by anodal transcranial direct current stimulation (tDCS) for over 24 h. Chronic administration of RBX converted cathodal tDCS-induced long-term depression-like plasticity into facilitation for 120 min. Chronic noradrenergic activity enhancement on plasticity of the human brain might partially explain the delayed therapeutic impact of selective NRIs in depression and other neuropsychiatric diseases...
November 7, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/27911740/the-puzzle-of-visual-development-behavior-and-neural-limits
#17
Lynne Kiorpes
The development of visual function takes place over many months or years in primate infants. Visual sensitivity is very poor near birth and improves over different times courses for different visual functions. The neural mechanisms that underlie these processes are not well understood despite many decades of research. The puzzle arises because research into the factors that limit visual function in infants has found surprisingly mature neural organization and adult-like receptive field properties in very young infants...
November 9, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27900437/bdnf-and-ltp-ltd-like-plasticity-of-the-primary-motor-cortex-in-gilles-de-la-tourette-syndrome
#18
L Marsili, A Suppa, F Di Stasio, D Belvisi, N Upadhyay, I Berardelli, M Pasquini, S Petrucci, M Ginevrino, G Fabbrini, F Cardona, G Defazio, A Berardelli
Gilles de la Tourette syndrome (GTS) is characterized by motor and vocal tics and often associated with obsessive-compulsive disorder (OCD). Responses to intermittent/continuous theta-burst stimulation (iTBS/cTBS), which probe long-term potentiation (LTP)-/depression (LTD)-like plasticity in the primary motor cortex (M1), are reduced in GTS. ITBS-/cTBS-induced M1 plasticity can be affected by brain-derived neurotrophic factor (BDNF) polymorphism. We investigated whether the BDNF polymorphism influences iTBS-/cTBS-induced LTP-/LTD-like M1 plasticity in 50 GTS patients and in 50 age- and sex-matched healthy subjects...
November 30, 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/27897671/high-intensity-interval-exercise-promotes-motor-cortex-disinhibition-and-early-motor-skill-consolidation
#19
Ellen L Stavrinos, James P Coxon
Gamma-aminobutyric acid (GABA) inhibition shapes motor cortex output, gates synaptic plasticity in the form of long-term potentiation, and plays an important role in motor learning. Remarkably, recent studies have shown that acute cardiovascular exercise can improve motor memory, but the cortical mechanisms are not completely understood. We investigated whether an acute bout of lower-limb high-intensity interval (HIT) exercise could promote motor memory formation in humans through changes in cortical inhibition within the hand region of the primary motor cortex...
November 29, 2016: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/27897203/reducing-gabaa-mediated-inhibition-improves-forelimb-motor-function-after-focal-cortical-stroke-in-mice
#20
Claudia Alia, Cristina Spalletti, Stefano Lai, Alessandro Panarese, Silvestro Micera, Matteo Caleo
A deeper understanding of post-stroke plasticity is critical to devise more effective pharmacological and rehabilitative treatments. The GABAergic system is one of the key modulators of neuronal plasticity, and plays an important role in the control of "critical periods" during brain development. Here, we report a key role for GABAergic inhibition in functional restoration following ischemia in the adult mouse forelimb motor cortex. After stroke, the majority of cortical sites in peri-infarct areas evoked simultaneous movements of forelimb, hindlimb and tail, consistent with a loss of inhibitory signalling...
November 29, 2016: Scientific Reports
keyword
keyword
71372
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"