Wirginia Krzyściak, Beata Bystrowska, Paulina Karcz, Robert Chrzan, Amira Bryll, Aleksander Turek, Paulina Mazur, Natalia Śmierciak, Marta Szwajca, Paulina Donicz, Katarzyna Furman, Fabio Pilato, Tamas Kozicz, Tadeusz Popiela, Maciej Pilecki
Given its polygenic nature, there is a need for a personalized approach to schizophrenia. The aim of the study was to select laboratory biomarkers from blood, brain imaging, and clinical assessment, with an emphasis on patients' self-report questionnaires. Metabolomics studies of serum samples from 51 patients and 45 healthy volunteers, based on the liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS/MS), led to the identification of 3 biochemical indicators (cortisol, glutamate, lactate) of schizophrenia...
February 15, 2024: International Journal of Molecular Sciences