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Mean corpuscular volume

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https://www.readbyqxmd.com/read/29770452/the-effects-of-blood-transfusion-on-red-blood-cell-distribution-width-in-critically-ill-patients-a-pilot-study
#1
Savino Spadaro, Fabio Silvio Taccone, Alberto Fogagnolo, Federico Franchi, Sabino Scolletta, Riccardo Ragazzi, Alberto Fanni, Elisabetta Marangoni, Maurizio Govoni, Roberto Reverberi, Carlo Alberto Volta
BACKGROUND: Red blood cell distribution width (RDW) is a measure of anisocytosis, generally used in the differential diagnosis of anemia. Recently, RDW was associated with increased mortality in critically ill patients. Red blood cell (RBC) transfusions are potential confounders on RDW values interpretation. The aim of this study was to analyze the changes in RDW after RBC transfusion in intensive care unit (ICU) patients. STUDY DESIGN AND METHODS: This was a prospective, observational study including patients admitted to ICU requiring 1 RBC unit...
May 16, 2018: Transfusion
https://www.readbyqxmd.com/read/29769008/biochemical-and-haematological-predictors-of-reduced-neutrophil-granulocyte-count-associated-with-intravenous-ceftriaxone-treatment
#2
Basant Puri, Anne Derham, Jean Monro
Background Intravenous treatment with ceftriaxone, a commonly used third-generation cephalosporin, is associated with a risk of the potentially fatal side-effect of neutropenia. Objective The first systematic study to determine whether six to 12 days' intravenous ceftriaxone treatment is associated with a reduction in the neutrophil count and the extent to which biochemical and/or haematological parameters routinely measured at baseline predict such a fall. Method Baseline and follow-up haematological and biochemical blood indices were measured in 86 patients (mean age 39...
May 16, 2018: Reviews on Recent Clinical Trials
https://www.readbyqxmd.com/read/29760679/hematocrit-values-predict-carotid-intimal-media-thickness-in-obese-patients-with-non-alcoholic-fatty-liver-disease-a-cross-sectional-study
#3
Giovanni Tarantino, Luigi Barrea, Domenico Capone, Vincenzo Citro, Teresa Mosca, Silvia Savastano
Background: Literature data suggest with some criticism that full-fledged cardiovascular (CV) events (acute or chronic) are likely predicted by blood components, which are reported to be associated with the presence/severity of non-alcoholic fatty liver disease (NAFLD). This study was aimed at determining which marker(s) derived from blood count, such as white blood cells, neutrophils, neutrophil/lymphocyte ratio, platelet count, hemoglobin, mean corpuscular volume, hematocrit values were associated with ear or subclinical atherosclerosis, in obese patients of various classes suffering from NAFLD...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29757873/management-of-vertebral-metastasis-in-patients-with-uterine-cervical-cancer
#4
Mustafa Kocaer, Varol Gülseren, İsa Aykut Özdemir, Özgü Güngördük, Emre Merter Mart, Muzaffer Sanci, Kemal Güngördük
AIM: We sought to identify risk factors and management options for uterine cervical cancer (UCC) patients with a vertebral metastasis (VM) treated over the course of 23 years. METHODS: Among 844 UCC patients, 18 were diagnosed with a VM. Thirty-six control patients with UCC but without recurrence were matched to these 18 in terms of stage and histological tumor type using a dependent random sampling method. A logistic regression analysis was used to identify factors prognostic of VM; the results are presented as odds ratios with 95% confidence intervals (CIs)...
May 4, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29743887/mean-corpuscular-volume-as-a-predictive-factor-of-response-to-preoperative-chemoradiotherapy-in-locally-advanced-rectal-cancer
#5
Wen-Yi Zhang, Xing-Xing Chen, Wen-Hao Chen, Hui Zhang, Chang-Lin Zou
Background: The aim of this study was to identify if blood routine parameters and serum tumor marker are potential predictive factors for tumor response to preoperative chemoradiotherapy (CRT) in locally advanced rectal cancer. Materials and Methods: 55 locally advanced rectal cancer patients were treated with preoperative CRT in this study. The total dose of preoperative radiotherapy was 45 Gy in 25 fractions of 1.8 in 5 weeks. All patients concurrently received 825 mg/m2 capecitabine orally twice daily on days 1 to 14 and 22 to 35...
2018: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/29736076/a-study-on-association-of-iron-deficiency-with-attention-deficit-hyperactivity-disorder-in-a-tertiary-care-center
#6
Kamirul Islam, Soutrik Seth, Suman Saha, Atanu Roy, Rajib Das, Asok Kumar Datta
Background: Iron is important for brain development and cognitive function. Iron deficiency may cause alteration of neurotransmitters and may be manifested by different central nervous system disorders including attention deficit hyperactivity disorder (ADHD). Aims: As studies are scarce in the Indian context, we had undertaken this study to find out the association between iron deficiency and ADHD. Settings and Design: Hospital-based cross-sectional study...
January 2018: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/29734258/red-cell-distribution-width-predicts-90-day-mortality-in-continuous-flow-left-ventricular-assist-device-patients
#7
Lauren K Truby, Lakshmi Sridharan, Raul J Flores, A Reshad Garan, Douglas Jennings, Melana Yuzefpolskaya, Koji Takeda, Hiroo Takayama, Yoshifumi Naka, Paolo C Colombo, Veli K Topkara
Red cell distribution width (RDW) measures the variance in size of circulating red blood cells and is a strong independent predictor of morbidity and mortality in cardiovascular disease and heart failure. Predictive power of RDW on mortality after continuous-flow left ventricular assist device (CF-LVAD) implantation remains largely unknown. Four hundred nine patients who underwent CF-LVAD implantation between April 2004 and December 2015 were retrospectively analyzed. The primary outcome of interest was 90 day mortality after CF-LVAD implantation...
April 19, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29722905/influence-of-biological-factors-on-hematological-and-serum-biochemistry-values-in-captive-ad%C3%A3-lie-chinstrap-gentoo-and-macaroni-penguins-in-pingtung-taiwan
#8
Shih-Yu Chen, Yi-Lun Tsai, Suen-Chuain Lin, Yeong-Huey Wu, Ming-Huei Liao, Ching-Dong Chang, Tsung-Hsien Li, Hsiao-Kuang Ho
Hematology and serum biochemistry reference values are essential for health evaluation and disease diagnosis in penguins. However, there are currently no published physiological values for captive Adélie (Pygoscelis adeliae) and Chinstrap penguins (P. antarcticus), nor for wild or captive Macaroni penguins (Eudyptes chrysolophus). The present study is the first investigation regarding hematology and serum biochemistry reference values for captive Adélie, Gentoo (P. papua), Chinstrap, and Macaroni penguins in Asia...
May 3, 2018: Zoo Biology
https://www.readbyqxmd.com/read/29722556/long-term-effect-of-sulfur-mustard-exposure-on-hematologic-and-respiratory-status-a-case-control-study
#9
Mohammad Reza Khazdair, Mohammad Hossein Boskabady
The long term effect of sulfur mustard (SM) exposure including, total and differential white blood cells (WBC), hematological parameters, pulmonary function tests (PFT), and respiratory symptoms (RS) in chemical war victims (CWV) exposed to SM 27-30 years ago were examined. Forty-six CWV and 42 control subjects with similar age from the general population were studied. Hematologic parameters, RS including; chest wheezing, night cough, night wheezing and cough, wheezing due to exercise (by Persian questionnaire), and PFT were assessed in all subjects...
May 3, 2018: Drug and Chemical Toxicology
https://www.readbyqxmd.com/read/29703633/oral-versus-intravenous-iron-supplementation-for-the-treatment-of-iron-deficiency-anemia-in-patients-on-maintenance-hemodialysis-effect-on-fibroblast-growth-factor-23-metabolism
#10
Wataru Fukao, Yukiko Hasuike, Tomo Yamakawa, Kazuhiro Toyoda, Makoto Aichi, Satoko Masachika, Mari Kantou, Shoko Ikeda Takahishi, Takahide Iwasaki, Mana Yahiro, Masatoshi Nanami, Yasuyuki Nagasawa, Takahiro Kuragano, Takeshi Nakanishi
OBJECTIVE: Iron administration affects serum levels of intact (I-) fibroblast growth factor-23 (FGF23) and its cleavage product C-terminal (C-) FGF23 in iron-deficient patients on maintenance hemodialysis (MHD). The objective of this study was to compare the effect of oral or intravenous iron administration on serum levels of I-FGF23 and C-FGF23 in iron-deficient patients on MHD. DESIGN AND METHODS: A prospective randomized study. SUBJECTS: Participants on MHD with severe iron deficiency (n = 61)...
April 24, 2018: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/29692590/hemolysis-area-a-new-parameter-of-erythrocyte-osmotic-fragility-for-screening-of-thalassemia-trait
#11
Thanusak Tatu, Denis Sweatman
BACKGROUND: One-tube osmotic fragility test (OFT) is widely used for screening thalassemia traits. Interobserver variation may occur with 0.36% NaCl-based OFT due to the naked eye result reading style. PURPOSE: The purpose of this study was to establish and evaluate the novel numerical OFT-based parameter, so-called hemolysis area (HA), in screening thalassemia traits. MATERIALS AND METHODS: The portable spectrophotometer was invented capable of calculating the HA values...
April 2018: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/29673334/full-blood-count-values-as-a-predictor-of-poor-outcome-of-pneumonia-among-hiv-infected-patients
#12
S Camon, C Quiros, N Saubi, A Moreno, M A Marcos, Y Eto, S Rofael, E Monclus, J Brown, T D McHugh, J Mallolas, R Perello
BACKGROUND: To evaluate the predictive value of analytical markers of full blood count that can be assessed in the emergency department for HIV infected patients, with community-acquired pneumonia (CAP). METHODS: Prospective 3-year study including all HIV-infected patients that went to our emergency department with respiratory clinical infection, more than 24-h earlier they were diagnosed with CAP and required admission. We assessed the different values of the first blood count performed on the patient as follows; total white blood cells (WBC), neutrophils, lymphocytes (LYM), basophils, eosinophils (EOS), red blood cells (RBC), hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin, red blood cell distribution width (RDW), platelets (PLT), mean platelet volume, and platelet distribution width (PDW)...
April 19, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29668567/anemia-in-pediatric-inflammatory-bowel-disease
#13
Ghanim Aljomah, Susan S Baker, Kenneth Schmidt, Razan Alkhouri, Rafal Kozielski, Lixin Zhu, Robert D Baker
OBJECTIVES: Anemia is the most frequent extra-intestinal finding in Inflammatory Bowel Disease. The aim of this study is to determine the prevalence and types of anemia in pediatric patients with Inflammatory Bowel Disease at diagnosis and at approximately one year follow up. METHODS: This is a retrospective chart review of patients diagnosed with Inflammatory Bowel Disease from 2005 to 2012, ages 1-18 years. Patients who had hemoglobin, hematocrit, mean corpuscular volume and iron indices obtained at the time of diagnosis and at approximately one year follow up were included in the study...
April 17, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29666560/storage-stability-of-commonly-used-haematological-parameters-at-33-%C3%A2-c-electronic-supplementary-material-available-online-for-this-article
#14
Ashish Jain, Sanchit Jain, Neha Singh, Priyanka Aswal, Shweta Pal, Sushant Kumar Meinia, Nilotpal Chowdhury
Introduction: This study aimed to investigate the analytical bias in haematological parameters induced by storage at 33 ºC. Materials and methods: Blood from the diversion pouch of 20 blood donors were collected in K 2 EDTA vials and stored at 33 ºC. Readings from each vial were taken at 0, 4, 6, 12, 24, 48 and 72 hours after collection on the Sysmex XP-100 analyser (Sysmex Corporation, Kobe, Japan). The percent difference from the baseline readings were calculated and subjected to a Wilcoxon signed rank test at a Holm corrected significance level of 0...
June 15, 2018: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/29665902/-mean-corpuscular-volume-can-be-a-predictor-for-therapeutic-response-of-patients-with-chronic-myeloid-leukemia
#15
Luo Lu, Chun Qiao, Ming Hong, Yan-Ru Li, Liang-Qin Pan, Si-Xuan Qian, Yu Zhu, Jian-Yong Li
OBJECTIVE: The past studies found that the treatment of chronic myeloid leukemia (CML) with imatinib can induce the macrocytic anemia, moreover the incidence of anemia increases along with enhancement of imatinib concentration. This study was aimed to evaluate the potential relation of erythrocyte mean corpuscular volume (MCV) increase after the treatment with tyrosine kinase inhibitors (TKI) with the therapeutic response in patients with CML-chronic phase (CML-CP). METHODS: The clinical and hematologic data including MCV, molecular and cytogenetic response of 119 patients with CML-CP were collected after treatment with TKIs, and the relation of MCV changes after treatment with the clinical characteristics and therapeutic efficacy for patients with CML-CP was analyzed...
April 2018: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/29661200/application-of-the-automated-haematology-analyzer-xn-30-in-an-experimental-rodent-model-of-malaria
#16
Takahiro Tougan, Yuhgi Suzuki, Munehisa Izuka, Kei Aono, Tomonori Okazaki, Yuji Toya, Kinya Uchihashi, Toshihiro Horii
BACKGROUND: The erythrocytic stage, where malaria parasites proliferate in human blood, is clinically significant as this causes the symptoms and illness of malaria. Experimental rodent models of malaria at the erythrocytic stage are used for the development of anti-malarial drugs and for biological analysis. An automated haematology analyzer XN-30 was developed for detection of infected red blood cells (iRBCs) in human blood samples and measurement of their parasitaemia in approximately 1 min through flow cytometry analysis...
April 16, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29660432/evaluation-of-hematological-and-biochemical-parameters-of-pesticide-retailers-following-occupational-exposure-to-a-mixture-of-pesticides
#17
Masoud Neghab, Hamed Jalilian, Shekoufeh Taheri, Mohsen Tatar, Zeynab Haji Zadeh
AIMS: Recently concern has been raised regarding possible health effects of exposure of pesticide retailers to chemicals they handle. Additionally, it is not known whether exposure to these compounds by retailers may be associated with any liver and kidney dysfunction or hematological abnormalities. This study was undertaken to address these issue. MAIN METHODS: In this cross-sectional study, 70 male pesticide retailers (cases) and 64 male subjects, randomly selected from the constructions workers of city council contractors, as the referent group, were investigated...
April 13, 2018: Life Sciences
https://www.readbyqxmd.com/read/29655636/reticulocyte-hemoglobin-content-in-a-large-sample-of-the-general-dutch-population-and-its-relation-to-conventional-iron-status-parameters
#18
A Mireille Baart, Michiel G J Balvers, Maria T E Hopman, Thijs M H Eijsvogels, Jacqueline M T Klein Gunnewiek, Corine A van Kampen
BACKGROUND: No full consensus exists on which iron status parameters to use for iron status assessment. In this study, we assessed the usefulness of measurement of the hemoglobin content of reticulocytes (CHr) in the general population. METHODS: The following iron status parameters were assessed in 1024 adults: CHr, reticulocytes, hemoglobin (Hb), ferritin, serum iron, transferrin, transferrin saturation and mean corpuscular volume (MCV). Mean parameter values and correlation coefficients for CHr and other parameters were calculated...
April 12, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29648997/interactive-effects-of-alcohol-and-chloroquine-on-hematologic-profile-of-wistar-rats
#19
Dimkpa Uchechukwu, Kelechi Loveth Ezeudensi, Babatunde Ishola Adejumo, Chinwe Obianuju Ewenighi, Elizabeth Enohnyaket Besong, Grace Ottah Umahi, Albert Nkereuwem Eteudo, Bright Uneze
BACKGROUND: There is paucity of information on the adverse effects of alcohol - chloroquine interaction on hematological parameters. To investigate the effects of concurrent administration of chloroquine and ethanol on hematologic parameters of adult Wistar rats and the ameliorative role of vitamin B12 and folic acid supplementation on any adverse effects. METHODS: Some 30 adult Wistar rats weighing 120-200 g were assigned to six major groups of five rats each according to their weights...
April 12, 2018: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/29629887/the-correlation-between-laboratory-markers-and-computed-tomography-severity-index-in-acute-appendicitis
#20
Yeliz Akturk, Serra Ozbal Gunes, Baki Hekimoglu
A M: This study aimed to evaluate and to investigate the association of some laboratory markers with the stage of the acute appendicitis. MATER AL AND METHODS: The hematological parameters (white blood cell count, red cell distribution width, platellet distribution width, mean corpuscular volume, and mean platelet volume values) and tomography scans of 200 patients who admitted to the emergency department with abdominal pain were retrospectively reviewed. Computed tomography grading about the severity of the cases was carried out by two radiologists, as grade 0 for normal appendix to grade 3 for perforated appencities...
2018: Annali Italiani di Chirurgia
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