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Mean corpuscular volume

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https://www.readbyqxmd.com/read/28920416/effects-of-aflatoxin-b1-combined-with-ochratoxin-a-and-or-zearalenone-on-metabolism-immune-function-and-antioxidant-status-in-lactating-dairy-goats
#1
Shuai Huang, Nan Zheng, CaiYun Fan, Ming Cheng, Shang Wang, Adil Jabar, JiaQi Wang, JianBo Cheng
Objective: This experiment was conducted to investigate the effects of aflatoxin B1 (AFB1) alone or mixed with ochratoxin A (OTA) and/or zearalenone (ZEA) on the metabolism, immune function, and antioxidant status of dairy goats. Methods: Fifty lactating Laoshan dairy goats were randomly assigned to one of five treatment groups (n = 10) for 14 days. Goats were fed no additive (control) or administered with 50 μg AFB1/kg DM (AFB1), 50 μg AFB1/kg DM + 100 μg OTA/kg DM (AFB1+OTA), 50 μg AFB1/kg DM + 500 μg ZEA/kg DM (AFB1+ZEA), or 50 μg AFB1/kg DM + 100 μg OTA/kg DM + 500 μg ZEA/kg DM (AFB1+OTA+ZEA)...
September 18, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28919829/age-and-sex-related-changes-in-hematological-parameters-in-healthy-malawians
#2
Wilson L Mandala, Esther N Gondwe, Jenny M MacLennan, Malcolm E Molyneux, Calman A MacLennan
AIM: The aim of the study was to determine how values for white blood cell (WBC) counts, hemoglobin (Hb), hematocrit (Hct), mean corpuscular volume (mcv), and platelet counts vary with age and sex in healthy Malawians. METHODS: We recruited 660 (316 male and 344 female) participants in 12 different age groups. An ethylenediaminetetraacetic acid-anticoagulated blood sample collected from each participant was analyzed using a hematological analyzer. RESULTS: WBC counts decreased with age with the lowest counts observed in the 20 to <60 years old group...
2017: Journal of Blood Medicine
https://www.readbyqxmd.com/read/28919711/protective-role-of-quercetin-against-manganese-induced-injury-in-the-liver-kidney-and-lung-and-hematological-parameters-in-acute-and-subchronic-rat-models
#3
Entaz Bahar, Geum-Hwa Lee, Kashi Raj Bhattarai, Hwa-Young Lee, Hyun-Kyoung Kim, Mallikarjun Handigund, Min-Kyung Choi, Sun-Young Han, Han-Jung Chae, Hyonok Yoon
Manganese (Mn) is an important mineral element required in trace amounts for development of the human body, while over- or chronic-exposure can cause serious organ toxicity. The current study was designed to evaluate the protective role of quercetin (Qct) against Mn-induced toxicity in the liver, kidney, lung, and hematological parameters in acute and subchronic rat models. Male Sprague Dawley rats were divided into control, Mn (100 mg/kg for acute model and 15 mg/kg for subchronic model), and Mn + Qct (25 and 50 mg/kg) groups in both acute and subchronic models...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28912725/enhanced-strength-and-sprint-levels-and-changes-in-blood-parameters-during-a-complete-athletics-season-in-800-m-high-level-athletes
#4
Beatriz Bachero-Mena, Fernando Pareja-Blanco, Juan J González-Badillo
The purpose of this study was to analyze changes in sprint, strength, hematological, and hormonal parameters in high-level 800 m athletes during a complete athletics season. Thirteen male athletes of national and international level in 800 m (personal best ranging from 1:43 to 1:58 min:ss) participated in this study. A total of 5 tests were conducted during a complete athletics season. Athletes performed sprint tests (20 and 200 m), countermovement jump (CMJ), jump squat (JS), and full squat (SQ) tests. Blood samples (red and white blood profile) and hormones were collected in test 1 (T1), test 3 (T3), and test 5 (T5)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28911652/microbiological-histological-and-biochemical-evidence-for-the-adverse-effects-of-food-azo-dyes-on-rats
#5
Khaled Elbanna, Osama Mohamed Sarhan, Manal Khider, Mohamed Elmogy, Hussein Hasan Abulreesh, Mohamed Rabie Shaaban
In this study, 120 lactic acid bacterial strains from different fermented dairy products as well as 10 bacterial intestinal isolates were evaluated for in vitro and in vivo degradation of various food azo dyes. Of these isolates, lactic acid bacteria (LAB) strains 13 and 100 and the intestinal isolates Ent2 and Eco5 exhibited 96-98% degradation of the tested food azo dyes within 5-6 hours. High performance liquid chromatography mass spectra of sunset yellow (E110) and carmoisine (E122) anaerobic degradation products by the intestinal isolates showed that they were structurally related to toxic aromatic amines...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28901887/microcytosis-is-associated-with-low-cognitive-outcomes-in-healthy-2-year-olds-in-a-high-resource-setting
#6
Elaine K McCarthy, Mairead E Kiely, Geraldine Hannon, Caroline Ahearne, Louise C Kenny, Jonathan O'B Hourihane, Alan D Irvine, Deirdre M Murray
Fe deficiency in early childhood is associated with long-term consequences for cognitive, motor and behavioural development; however explorations in healthy children from low risk, high-resource settings have been limited. We aimed to explore associations between Fe status and neurodevelopmental outcomes in low risk, healthy 2-year-olds. This study was a secondary analysis of a nested case-control subgroup from the prospective, maternal-infant Cork Babies after Screening for Pregnancy Endpoints: Evaluating the Longitudinal Impact using Neurological and Nutritional Endpoints (BASELINE) Birth Cohort Study...
September 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28899777/jerusalem-artichoke-enriched-diet-on-growth-performance-immuno-hematological-changes-and-disease-resistance-against-aeromonas-hydrophila-in-asian-seabass-lates-calcarifer
#7
Sajjad Syed Raffic Ali, Kondusamy Ambasankar, Mohamed Saiyad Musthafa, Ramasamy Harikrishnan
A 45 days feeding trial was conducted to study the effect of Jerusalem artichoke (JA) on growth performance, body composition, biochemical, immuno-hematological parameters and disease resistance in Asian seabass (Lates calcarifer) fingerlings against Aeromonas hydrophila. JA was supplemented at three different levels viz., control 0, 5, 10, and 20 g kg(-1) in the commercial diet (403 g kg(-1)protein and 89 g kg (-1)lipid) in L. calcarifer. The results showed that there were no significant (P > 0...
September 9, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28892906/changes-in-haematological-parameters-in-newborns-born-to-preeclamptic-mothers-a-case-control-study-in-a-rural-hospital
#8
Kalavakuru Mouna, Shilpa Manigatta Doddagowda, Krishnappa Junjegowda, Latha Krishnamurthy
INTRODUCTION: Pregnancy is a physiological phenomenon. However, some women develop problems during pregnancy period, which puts both the mother's and the foetus health at risk. Hypertensive disorders of pregnancy are the type of the maternal diseases that can cause the most detrimental effects to the mother and foetus. AIMS: To determine the haematological parameters in neonates born to preeclamptic mothers. MATERIALS AND METHODS: It was a prospective case control study carried out on neonates born to preeclamptic mothers in our institute from March 2016 to November 2016...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28872486/comparison-of-different-iron-preparations-in-the-prophylaxis-of-iron-deficiency-anemia
#9
Ali Aydin, Emel Gur, Tugba Erener-Ercan, Gunay Can, Ahmet Arvas
We compared the efficacy of ferrous sulfate (divalent) and ferric polymaltose (trivalent) compounds for the prophylaxis of iron-deficiency anemia (IDA). Study infants included exclusively breast milk-fed term infants. Subjects were divided randomly into 2 groups at 4 months of age and group 1 (n=56) received divalent and group 2 (n=56) received trivalent iron (Fe) preparation at a dose of 2 mg/kg/d for 5 months. At 9 months of age, after a 5-month prophylaxis, a significant increase was observed in hemoglobin (Hb), hematocrit, serum Fe levels, and transferrin saturation in both groups...
September 1, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28869958/management-of-nephrotic-syndrome-a-case-report-from-lao-pdr
#10
Phanekham Souvannamethy
We report the case of a 23-year-old woman with a 2-week history of swelling around the eyes and both legs, and generalized body swelling. She had a history of chronic constipation and poor diet but no fever, recent illnesses, or hematuria. Examination revealed bilateral pedal edema and mild ascites. Laboratory investigations showed low hemoglobin 79 g/L, low mean corpuscular volume 53 fL, thrombocytosis 973 × 109/L, and marked hypochromia and microcytosis, with low iron and ferritin. She had hypoalbuminemia and reduced serum protein (albumin 1...
2017: Blood Purification
https://www.readbyqxmd.com/read/28861128/pyrosequencing-quantified-methylation-level-of-mir-124-predicts-shorter-survival-for-patients-with-myelodysplastic-syndrome
#11
Hong Wang, Tong-Tong Zhang, Song Jin, Hong Liu, Xiang Zhang, Chang-Geng Ruan, De-Pei Wu, Yue Han, Xiao-Qin Wang
BACKGROUND: Aberrant CpG island methylation has been increasingly recognized as a common event in myelodysplastic syndrome (MDS). To date, most of the previous studies of miR-124 in MDS have focused on epigenetic changes and little is known about the underlying mechanism through which miR-124 regulates CDK6 expression. RESULTS: In the present study, we employed pyrosequencing analysis to quantify the methylation levels of upstream regions of the miR-124 genes (miR-124-1, miR-124-2 and miR-124-3) in 56 primary MDS patients...
2017: Clinical Epigenetics
https://www.readbyqxmd.com/read/28831229/baseline-hematology-and-serum-biochemistry-results-for-indian-leopards-panthera-pardus-fusca
#12
Arun Attur Shanmugam, Sanath Krishna Muliya, Ajay Deshmukh, Sujay Suresh, Anukul Nath, Pa Kalaignan, Manjunath Venkataravanappa, Lyju Jose
AIM: The aim of the study was to establish the baseline hematology and serum biochemistry values for Indian leopards (Panthera pardus fusca), and to assess the possible variations in these parameters based on age and gender. MATERIALS AND METHODS: Hemato-biochemical test reports from a total of 83 healthy leopards, carried out as part of routine health evaluation in Bannerghatta Biological Park and Manikdoh Leopard Rescue Center, were used to establish baseline hematology and serum biochemistry parameters for the subspecies...
July 2017: Veterinary World
https://www.readbyqxmd.com/read/28829493/effects-of-il-10-on-iron-metabolism-in-lps-induced-inflammatory-mice-via-modulating-hepcidin-expression
#13
P Huang, J Wang, X Lin, F-F Yang, J-H Tan
OBJECTIVE: Body's iron metabolism is at one dynamic balance status, and abnormal iron metabolism may lead to renal anemia. Inflammation stimuli may lead to abnormal iron metabolism and aggravation of chronic failure anemia. Hepcidin can regulate iron metabolic homeostasis, further mediating renal anemia. Interleukin-10 (IL-10) is an inflammatory inhibitor, but with an unclear function in the regulation of hepcidin expression. MATERIALS AND METHODS: BALB/c mice were randomly assigned into three groups: control group; lipid polysaccharide (LPS) group, which received 0...
August 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28820550/is-fasting-for-ramadan-safe-in-patients-with-mechanical-cardiac-valves
#14
Ersin Yildirim, Ozlem Secen, Okkes Uku, Mehmet Nail Bilen, Makbule Kutlu Karadag
BACKGROUND: The study aim was to investigate the safety and effects of fasting during Ramadan on the International Normalized Ratio (INR) in patients with mechanical cardiac valves. METHODS: A total of 105 patients admitted to the authors' hospital between June and October 2015, who had history of prosthetic valve replacement, was investigated. The patients were allocated to two groups: those fasting during Ramadan (n = 42) and those not fasting (n = 63). All patients were examined by a cardiologist, and the clinical findings and complaints for the past three months were evaluated...
March 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28819422/the-neutrophil-lymphocyte-ratio-predicts-recurrence-of-cervical-intraepithelial-neoplasia
#15
Sungwook Chun, Kyusik Shin, Ki Hyung Kim, Heung Yeol Kim, Wankyu Eo, Ji Young Lee, Jeong Namkung, Sang Hoon Kwon, Suk Bong Koh, Hong-Bae Kim
OBJECTIVE: The purpose of the present study was to determine the prognostic significance of the neutrophil-lymphocyte ratio (NLR) in recurrence of cervical intraepithelial neoplasia (CIN). METHODS: We evaluated the NLR as a prognostic marker in the entire cohort of 230 patients who had undergone surgical resection and were diagnosed with CIN. Subjects were categorized into two different groups based on the NLR (NLR-high and NLR-low) using cutoff values determined by receiver operating characteristic (ROC) analysis...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28795619/hematological-and-molecular-characterization-of-a-novel-hb-a2-variant-with-homozygous-%C3%AE-thalassemia-2-in-a-southern-thai-individual
#16
Manit Nuinoon, Nutjaree Jeenduang, Aumpika Kesornsit, Dararat Horpet, Thunyaluk Plyduang
We report here the hematological and molecular features of a novel δ-globin chain variant found in a Southern Thai woman. Her complete blood count was as follows: red blood cell (RBC) count 5.90 × 10(12)/L, hemoglobin concentration (Hb) 12.6 g/dL, packed cell volume (PCV) 0.41 L/L, mean corpuscular volume (MCV) 69.5 fL, mean corpuscular Hb (MCH) 21.4 pg, mean corpuscular Hb concentration (MCHC) 30.7 g/dL and RBC distribution width (RDW) 13.1%. The blood smear demonstrated microcytic hypochromic RBCs suggestive of thalassemia trait...
August 10, 2017: Hemoglobin
https://www.readbyqxmd.com/read/28795308/the-mean-corpuscular-volume-as-a-prognostic-factor-for-colorectal-cancer
#17
Hidemasa Nagai, Norihiro Yuasa, Eiji Takeuchi, Hideo Miyake, Yuichiro Yoshioka, Kanji Miyata
PURPOSE: The aim of the present study was to identify the factors investigated during routine blood examinations which can predict the disease outcome independent of the tumor stage. METHODS: Data from 1174 patients with stage I, II, and III CRC who underwent R0 resection were included. We investigated the correlations between the preoperative routine blood examination data, and clinicopathological factors, and disease-free survival (DFS) using univariate and multivariate analyses...
August 9, 2017: Surgery Today
https://www.readbyqxmd.com/read/28792691/increased-red-blood-cell-volume-distribution-width-important-clinical-implications-in-predicting-gastric-diseases
#18
Taijie Li, Aidan Huang, Meiyu Zhang, Fang Lan, Dawei Zhou, Huiping Wei, Zhiming Liu, Xue Qin
BACKGROUND: The red blood cell distribution width (RDW) is a blood analyzer marker showing the peripheral blood erythrocyte volume heterogeneity parameters. It is a normal diagnosis index of many diseases. This study was performed to evaluate the relationship between the RDW and gastric diseases. METHODS: A total of 189 patients with GC, 68 patients with gastric ulcers, 92 patients with chronic gastritis, and 157 healthy controls were enrolled in this study. Each patient's RDW and other biomarkers were recorded...
July 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28790546/effect-of-cigarette-smoking-on-haematological-parameters-in-healthy-population
#19
Maja Malenica, Besim Prnjavorac, Tamer Bego, Tanja Dujic, Sabina Semiz, Selma Skrbo, Amar Gusic, Ajla Hadzic, Adlija Causevic
OBJECTIVE: Tobacco cigarette smoking is one of the major leading causes of death throughout the world. Smoking has both acute and chronic effect on haematological parameters. The aim of the present study was to assess the extent of adverse effects of cigarette smoking on biochemical characteristics in healthy smokers. SUBJECTS AND METHOD: One hundred and fifty six subjects participated in this study, 56 smokers and 100 non-smokers. The smokers were regularly consuming 10-20 cigarettes per day for at least 3 years...
April 2017: Medical Archives
https://www.readbyqxmd.com/read/28783892/effect-of-hyperbaric-oxygen-therapy-on-complete-blood-count
#20
Ali Erdal Gunes, Samil Aktas
Complete blood count (CBC) is a routine diagnostic procedure for patients and a part of routine health inspection for healthy individuals. The effect of hyperbaric oxygen (HBO₂) on CBC is not known. The objective of this study was to determine the effects of HBO₂ on blood parameters in CBC with long-term HBO₂ therapy. In this study, patients received HBO₂ at the department of Underwater and Hyperbaric Clinical Medicine. CBC results were obtained at specific time points during HBO₂ therapy. The study recruited a total of 140 patients who met the research inclusion criteria...
July 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
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