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https://www.readbyqxmd.com/read/28510724/relationship-between-the-magnetic-resonance-imaging-appearance-of-adenomyosis-and-endometriosis-phenotypes
#1
Charles Chapron, Claudia Tosti, Louis Marcellin, Mathilde Bourdon, Marie-Christine Lafay-Pillet, Anne-Elodie Millischer, Isabelle Streuli, Bruno Borghese, Felice Petraglia, Pietro Santulli
STUDY QUESTION: What is the relationship between endometriosis phenotypes superficial peritoneal endometriosis (SUP), ovarian endometrioma (OMA), deep infiltrating endometriosis (DIE) and the adenomyosis appearance by magnetic resonance imaging (MRI)? SUMMARY ANSWER: Focal adenomyosis located in the outer myometrium (FAOM) was observed more frequently in women with endometriosis, and was significantly associated with the DIE phenotype. WHAT IS KNOWN ALREADY: An association between endometriosis and adenomyosis has been reported previously, although data regarding the association between MRI appearance of adenomyosis and the endometriosis phenotype are currently still lacking...
May 16, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28506797/-systematic-proposal-of-fertility-preservation-by-mature-oocyte-cryopreservation-for-recurrent-benign-ovarian-tumors
#2
Y Dadoun, H Azaïs, L Keller, E d'Orazio, P Collinet, C Decanter
OBJECTIVES: To investigate prospectively the pattern of the follicular growth and to characterize the COH outcome in terms of oocyte number and maturity in patients with voluminous recurrent benign ovarian tumors with a high surgical risk of significant reduction of the ovarian follicular content. METHODS: The inclusion criteria were: age between 18 and 36, presence of at least one benign ovarian tumor (≥ 5cm) with high risk of recurrence. The fertility preservation cycle was performed at least 3 months after the cyst surgery...
May 12, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/28501371/endometriosis-on-the-uterosacral-ligament-a-marker-of-ureteral-involvement
#3
Raquel Lima, Helizabet Abdalla-Ribeiro, Ana Luisa Nicola, Aline Eras, Anna Lobao, Paulo Ayroza Ribeiro
OBJECTIVE: To evaluate the association between ultrasound measurements of endometriosis nodules on the uterosacral ligament (USL) and the risk of ureteral involvement, as well as to assess whether associations with other ultrasound variables increase the sensitivity and specificity of the diagnosis of ureteral endometriosis. DESIGN: Cross-sectional, observational study. SETTING: University hospital. PATIENT(S): Four hundred sixty-three women with deep infiltrating endometriosis (DIE)...
May 10, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28498960/which-is-worse-comparison-of-art-outcome-between-women-with-primary-or-recurrent-endometriomas
#4
Baris Ata, Sezcan Mumusoglu, Kiper Aslan, Ayse Seyhan, Isil Kasapoglu, Berrin Avci, Bulent Urman, Gurkan Bozdag, Gurkan Uncu
STUDY QUESTİON: Are live birth rates (LBR) different after ART cycles between women with primary or recurrent endometrioma? SUMMARY ANSWER: Women with recurrent endometrioma have similar LBR as compared to patients with primary endometrioma. WHAT IS ALREADY KNOWN: Recurrence rate can be as high as 29% after endometrioma excision. Prior studies on management of endometrioma before ART involve primary endometriomas. There is limited information regarding the prognosis of women with recurrent endometriomas...
May 12, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28495852/high-throughput-mrna-sequencing-of-stromal-cells-from-endometriomas-and-endometrium
#5
Kadri Rekker, Merli Saare, Elo Eriste, Tõnis Tasa, Viktorija Kukuškina, Anne Mari Roost, Kristi Anderson, Külli Samuel, Helle Karro, Andres Salumets, Maire Peters
The aetiology of endometriosis is still unclear and to find mechanisms behind the disease development it is important to study each cell type from endometrium and ectopic lesions independently. The objective of this study was to uncover complete mRNA profiles in uncultured stromal cells from paired samples of endometriomas and eutopic endometrium. High-throughput mRNA sequencing revealed over 1,300 dysregulated genes in stromal cells from ectopic lesions, including several novel genes in the context of endometriosis...
May 11, 2017: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/28470024/ovarian-endometrioma-superinfected-with-salmonella-case-report-and-review-of-the-literature
#6
Max W Adelman, Jacob H Johnson, Elizabeth L Hohmann, Rajesh T Gandhi
We present the case of a 28-year-old woman with Salmonella serovar Schwarzengrund gastroenteritis acquired during foreign travel. Her case was complicated by superinfection of a pre-existing ovarian endometrioma with a quinolone-resistant organism; the resultant ovarian abscess ultimately required surgical removal for resolution. We review the key features of this case and the previous literature on Salmonella ovarian abscess. This report highlights (1) the potential for metastatic spread of Salmonella to the ovary in women with pre-existing cysts or endometriomas and (2) the increasing worldwide burden of quinolone-resistant Salmonella...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28454508/endometrial-flushing-%C3%AE-v%C3%AE-3-integrin-glycodelin-and-pgf2%C3%AE-levels-for-evaluating-endometrial-receptivity-in-women-with-polycystic-ovary-syndrome-myoma-uteri-and-endometrioma
#7
Mustafa Demir, Onur Ince, Bulent Ozkan, Sefa Kelekci, Recep Sutcu, Bulent Yilmaz
The aim of this cross-sectional study is to compare endometrial flushing fluid levels of αVβ3 integrin, glycodelin and PGF2α during the midluteal phase of the menstrual cycle of women with polycystic ovary syndrome (PCOS, n = 20), myoma uteri (n = 20) and endometrioma (n = 19) with the healthy controls (n = 20). After collecting samples at the midluteal phase of ovulatory volunteers and storing them at -80 °C, αVβ3 integrin, glycodelin and PGF2α levels were analyzed using ELISA. The mean ages of the groups were 28...
April 28, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28438065/reduced-expression-of-eukaryotic-translation-initiation-factor-3-subunit-e-and-its-possible-involvement-in-the-epithelial-mesenchymal-transition-in-endometriosis
#8
Xianjun Cai, Minhong Shen, Xishi Liu, Sun-Wei Guo
Epithelial-mesenchymal transition (EMT) is now well documented to be involved in the development of endometriosis through the promotion of invasion and fibrogenesis. To date, several factors have been reported to be involved in EMT in endometriosis. The eukaryotic translation initiation factor 3 subunit e (eIF3e) protein is a component of the multisubunit eIF3 complex essential for cap-dependent translation initiation. The aim of this study was to investigate whether eIF3e is involved in EMT in endometriosis...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28421599/surgery-versus-conservative-management-of-endometriomas-in-subfertile-women-a-systematic-review
#9
Jacob Brink Laursen, Jeppe Bennekou Schroll, Kirsten T Macklon, Martin Rudnicki
INTRODUCTION: Endometriomas are present in up to 44% of all women with endometriosis and have a detrimental effect on fertility. However, it is controversial whether endometriomas should be surgically removed before assisted reproduction technology (ART). Our purpose was to evaluate whether surgical stripping of endometriomas in subfertile women improves the chance of a live birth. Secondary outcomes were impact on ovarian reserve and pain. Material and methods We conducted a systematic review and metaanalysis with results reported in accordance to the PRISMA guidelines...
April 19, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28417349/a-higher-prevalence-of-endometriosis-among-asian-women-does-not-contribute-to-poorer-ivf-outcomes
#10
Ayae Yamamoto, Erica B Johnstone, Michael S Bloom, Heather G Huddleston, Victor Y Fujimoto
PURPOSE: The purpose of the study was to determine whether diagnosis of endometriosis or endometriosis with endometrioma influences in vitro fertilization (IVF) outcomes in an ethnically diverse population. METHODS: Women undergoing a first IVF cycle (n = 717) between January 1, 2008 and December 31, 2009, at a university-affiliated infertility clinic, were retrospectively assessed for an endometriosis diagnosis. Differences in prevalence of endometriosis by ethnicity were determined, as well as differences in IVF success by ethnicity, with a focus on country of origin for Asian women...
April 17, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28414865/transvaginal-sonography-in-the-diagnosis-of-deep-infiltrating-endometriosis-a-review
#11
Jenna M Turocy, Beryl R Benacerraf
This review summarizes the current evidence regarding the diagnostic accuracy of sonography (US) in women with deep infiltrating endometriosis (DIE). It is well known that transvaginal ultrasound (TVUS) can detect ovarian endometriomas with a high degree of sensitivity. In recent years, US has also been used to detect DIE. In the hands of an experienced sonologist, the sensitivity and specificity of TVUS in the detection of DIE is comparable to those of MRI. TVUS can eliminate the need for an MRI in the majority of patients and reduce the need for diagnostic laparoscopy, proving to be an important tool in preoperative planning...
April 17, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28407512/impact-of-large-ovarian-endometriomas-on-the-response-to-superovulation-for-in-vitro-fertilization-a-retrospective-study
#12
Simone Ferrero, Carolina Scala, Emanuela Tafi, Annalisa Racca, Pier Luigi Venturini, Umberto Leone Roberti Maggiore
OBJECTIVE: To assess the response to superovulation for in vitro fertilization (IVF) in patients with unilateral endometriomas with diameter ≥5cm and in the contralateral healthy ovary. STUDY DESIGN: This retrospective analysis of a prospectively collected database included patients who underwent superovulation for IVF/ICSI cycles and had unoperated single unilateral endometrioma with diameter ≥5cm and healthy contralateral ovary. The primary outcome of the study was to compare the number of oocyte retrieved in the ovary with the endometrioma and the contralateral healthy ovary...
April 2, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28403916/-conservative-management-of-endometrioma-in-women-undergoing-in-vitro-fertilization
#13
REVIEW
P Santulli, E Somigliana, M Bourdon, C Maignien, L Marcellin, V Gayet, C Chapron
Endometriosis is a chronic disease. The pathogenesis is actually still unclear. Endometriosis is responsible for infertility and/or pelvic pain. One of the most important features of the disease is the heterogeneity (clinical and anatomical). Among the different phenotypes of endometriosis, the ovarian endometrioma seems to most important lesion in the management of endometriosis-related infertility. Surgical treatment is associated to a decrease of the ovarian reserve and a potential detrimental effect on in vitro fecondation (IVF) outcomes...
March 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28400829/a-case-control-study-of-bisphenol-a-and-endometrioma-among-subgroup-of-iranian-women
#14
Batool Hossein Rashidi, Massoud Amanlou, Tahere Behrouzi Lak, Mahya Ghazizadeh, Bita Eslami
BACKGROUND: Endometriosis is a multifactorial hormonally related complex disease with unknown etiology. Epidemiologic data were suggested the possible effects of endocrine disrupting chemicals such as bisphenol A (BPA) on endometriosis. BPA is similar to endogenous estrogen and has the ability to interact with estrogen receptors and stimulate estrogen production. Our aim was to evaluate the relationship between urinary BPA concentrations in women with endometrioma. MATERIALS AND METHODS: This case-control study consisted of fifty women who have been referred to gynecology and infertility center with endometrioma and were candidates for operative laparoscopy and ovarian cystectomy as cases...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28376925/serum-and-peritoneal-fluid-concentrations-of-soluble-human-leukocyte-antigen-tumor-necrosis-factor-alpha-and-interleukin-10-in-patients-with-selected-ovarian-pathologies
#15
Olimpia Sipak-Szmigiel, Piotr Włodarski, Elżbieta Ronin-Walknowska, Andrzej Niedzielski, Beata Karakiewicz, Sylwia Słuczanowska-Głąbowska, Maria Laszczyńska, Witold Malinowski
BACKGROUND: Although immune system plays a key role in the pathogenesis of both endometriosis and ovarian cancer, its function is different. Therefore, we hypothesized, that selected immune parameters can serve as diagnostic markers of these two conditions. The aim of this study was to compare serum and peritoneal fluid concentrations of sHLA-G, IL-10 and TNF-alpha in women with selected ovarian pathologies: benign serous cysts, endometrioma and malignant tumors. Clinical significance of using them for diagnostic purposes in women with serous ovarian cysts, endometriosis, and ovarian cancer, which in the future may improve the early diagnosis of ovarian diseases...
April 4, 2017: Journal of Ovarian Research
https://www.readbyqxmd.com/read/28366418/spontaneous-fertility-after-expectant-or-surgical-management-of-rectovaginal-endometriosis-in-women-with-or-without-ovarian-endometrioma-a-retrospective-analysis
#16
Umberto Leone Roberti Maggiore, Carolina Scala, Emanuela Tafi, Annalisa Racca, Ennio Biscaldi, Valerio Gaetano Vellone, Pier Luigi Venturini, Simone Ferrero
OBJECTIVE: To investigate spontaneous pregnancy rate (SPRs) of women with rectovaginal endometriosis (RV) with/without ovarian endometrioma (OMA) and treated with the use of expectant or surgical management. DESIGN: Retrospective study. SETTING: University hospital. PATIENT(S): The study included patients with RV with or without OMA who tried to conceive spontaneously for 1 year either without undergoing surgery (group E; n = 284) or after surgery (group S; n = 221)...
April 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28348653/magnetic-resonance-imaging-mri-depiction-of-robert-s-uterus-a-rare-m%C3%A3-llerian-duct-anomaly-presenting-with-cyclical-pain-in-young-menstruating-woman
#17
Puneet Mittal, Ranjana Gupta, Amit Mittal, Arpit Taneja, Preetparkash Singh Sekhon, Sharad Gupta
BACKGROUND: Robert's uterus is a very rare müllerian duct anomaly which is characterised by septate uterus with obstruction of a one-sided cavity and formation of hematometra. Therefore, patients present with cyclical abdominal pain during menstruation along with normal menstrual flow. CASE REPORT: We present magnetic resonance imaging (MRI) findings in a case of Robert's uterus in a young woman. CONCLUSIONS: Robert's uterus is a very rare anomaly which can be very well characterized by magnetic resonance imaging (MRI)...
2017: Polish Journal of Radiology
https://www.readbyqxmd.com/read/28345488/deep-infiltrating-endometriosis-and-endometrial-adenocarcinoma-express-high-levels-of-myostatin-and-its-receptors-messenger-rnas
#18
Patrizia Carrarelli, Lucia Funghi, Pasquapina Ciarmela, Gabriele Centini, Fernando M Reis, Cynthia Dela Cruz, Alberto Mattei, Silvia Vannuccini, Felice Petraglia
Myostatin is a growth factor member of the transforming growth factor β superfamily, which is known to play major roles in cell proliferation and differentiation. The present study investigated the messenger RNA (mRNA) expression of myostatin and myostatin receptors (activin receptor-like kinase 4 [ALK4], transforming growth factor (TGF)-β type I receptor kinase [ALK5] and activin receptor type IIB [ActRIIB]) in endometrium of healthy women during menstrual cycle as well as in benign (endometriosis, polyps) and malignant (endometrial adenocarcinoma) conditions...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28342392/value-of-the-68-ga-dotatate-pet-ct-in-the-diagnosis-of-endometriosis-a-pilot-study
#19
M Fastrez, C Artigas, N Sirtaine, Z Wimana, M Caillet, S Rozenberg, P Flamen
OBJECTIVE: The non-invasive diagnosis of endometriosis remains challenging. Recent data suggested that somatostatin might be involved in its pathogenesis. High sensitive visualization of somatostatin receptors expression is possible using PET-CT imaging after the administration of a (68)Ga-labeled somatostatin analog (DOTATATE) that will bind to the somatostatin receptor sub-types 2 and 5. The aim of the present study was to assess the usefulness of (68)Ga-DOTATATE PET-CT in the diagnosis of endometriosis...
May 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28314166/effects-of-long-term-postoperative-dienogest-use-for-treatment-of-endometriosis-on-bone-mineral-density
#20
Jong-Wook Seo, Dong-Yun Lee, Byung-Koo Yoon, DooSeok Choi
OBJECTIVE: This study was conducted to evaluate the effects of long-term postoperative dienogest (DNG) use for the treatment of endometriosis on bone mineral density (BMD). STUDY DESIGN: Sixty reproductive-aged women who underwent conservative surgery for endometriomas and received postoperative DNG (2mg/day) for at least 12 months to prevent recurrence were analyzed. BMD was measured before and after DNG treatment by using dual energy X-ray absorptiometry, and changes in BMD were evaluated...
May 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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