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https://www.readbyqxmd.com/read/27911020/changes-in-resting-state-connectivity-in-musicians-with-embouchure-dystonia
#1
Bernhard Haslinger, Jonas Noé, Eckart Altenmüller, Valentin Riedl, Claus Zimmer, Tobias Mantel, Christian Dresel
OBJECTIVE: Embouchure dystonia is a highly disabling task-specific dystonia in professional brass musicians leading to spasms of perioral muscles while playing the instrument. As they are asymptomatic at rest, resting-state functional magnetic resonance imaging in these patients can reveal changes in functional connectivity within and between brain networks independent from dystonic symptoms. METHODS: We therefore compared embouchure dystonia patients to healthy musicians with resting-state functional magnetic resonance imaging in combination with independent component analyses...
December 2, 2016: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/27910134/effectiveness-of-handmade-jacky-like-catheter-as-a-single-multipurpose-catheter-in-transradial-coronary-angiography-a-randomized-comparison-with-conventional-two-catheter-strategy
#2
Ismail Erden, Ebru Golcuk, Serdar Bozyel, Emine Cakcak Erden, Yakup Balaban, Kivanc Yalın, Burak Turan
OBJECTIVE: To investigate safety and efficacy of specialized hand-modified "Jacky-Like" catheter (JLC) as a single dual-purpose catheter in transradial coronary angiography. METHODS: Patients over 18 years undergoing diagnostic CAG through right radial artery (RRA) were prospectively enrolled. Procedures were performed with a single JLC modified from a left Judkins (JL) 3.5 catheter or by using 2-catheter approach (2C). Procedures with coronary artery bypass grafts or ventricular angiographies were excluded from the study...
December 2, 2016: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/27759565/intramuscular-neurotrophin-3-normalizes-low-threshold-spinal-reflexes-reduces-spasms-and-improves-mobility-after-bilateral-corticospinal-tract-injury-in-rats
#3
Claudia Kathe, Thomas Haynes Hutson, Stephen Brendan McMahon, Lawrence David Falcon Moon
Brain and spinal injury reduce mobility and often impair sensorimotor processing in the spinal cord leading to spasticity. Here, we establish that complete transection of corticospinal pathways in the pyramids impairs locomotion and leads to increased spasms and excessive mono- and polysynaptic low threshold spinal reflexes in rats. Treatment of affected forelimb muscles with an adeno-associated viral vector (AAV) encoding human Neurotrophin-3 at a clinically-feasible time-point after injury reduced spasticity...
October 19, 2016: ELife
https://www.readbyqxmd.com/read/27651808/comparison-of-antispasmodic-effect-of-hydroalcoholic-extract-of-dracocephalum-kotschyi-boiss-in-rat-uterus-and-ileum
#4
Hassan Sadraei, Gholamreza Asghari, Mahla Alinejad
Dracocephalum kotschyi Boiss. is a traditional medicine with antispasmodic activities. The objective of this research was to study antispasmodic activities of hydroalcoholic extract of D. kotschyi on rat isolated uterus contractions for comparison with isolated ileum. Hydroalcoholic extract was obtained from aerial part of D. kotschyi using percolation method. A portion of rat ileum or uterus was suspended in Tyrode's solution at 37°C and gassed with O2. Effect of D. kotschyi extract was assessed on ileum or uterus contractions induced by KCl (80 mM), acetylcholine (ACh, 500 nM), electrical field stimulation (EFS) or oxytocin (0...
July 2016: Research in Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27515204/accommodative-spasm-might-influence-surgical-planning-and-outcomes-in-acute-acquired-distance-esotropia-in-myopia
#5
Michela Fresina, Giuseppe Giannaccare, Piera Versura, Emilio C Campos
INTRODUCTION: Acute acquired distance esotropia (AADE) is a poorly understood moderate-angle strabismus, affecting young adult myopes and determining bothersome diplopia. Symptoms can be intermittent in the early stages, becoming constant in long-lasting disease. Symptomatic therapy includes prism correction, while surgery is the only curative treatment. However, the latter is affected by high rate of symptoms recurrence with the frequent need for reoperation. HYPOTHESIS: We hypothesize that AADE could be caused by the increase of the accommodative demand, often secondary to a myopic overcorrection...
September 2016: Medical Hypotheses
https://www.readbyqxmd.com/read/27134989/limbus-vertebra-presenting-with-inflammatory-low-back-pain-a-case-report
#6
Serpil Tuna, Tayfun Özdemir, Hande Ece Öz
Limbus vertebra is a condition characterized by marginal interosseous herniation of the nucleus pulposus, and causes non specific symptoms like low back pain, back pain, muscle spasms and radiculopathy. It is frequently confused with vertebral fracture, infection, schmorl nodule or tumour because it has not a spesific symptom. It usually causes mechanical low back pain rather than inflammatory low back pain. We reported a patient presented with inflammatory low back pain and diagnosed with anterior limbus vertebra because it is rare and the patient has atypical clinical presentation...
March 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26848858/assessment-of-pelvic-floor-muscles-in-women-with-deep-endometriosis
#7
Ana Paula Santos Dos Bispo, Christine Ploger, Alessandra Fernandes Loureiro, Hélio Sato, Alexander Kolpeman, Manoel João Batista Castello Girão, Eduardo Schor
PURPOSE: To assess function and prevalence of spasms and trigger points of the pelvic floor muscles in women with deep endometriosis. METHODS: One hundred and four (104) patients were assessed. Group 1 (G1) was composed of 52 subjects diagnosed with deep endometriosis proven by magnetic resonance imaging (MRI); Group 2 (G2) was composed of 52 women with no signs of endometriosis. Subjects from both G1 and G2 were seen at the Division of Pelvic Pain and Endometriosis and at Center for Prevention of Sexually Transmitted Diseases, both at Federal University of São Paulo (UNIFESP), respectively...
September 2016: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/26571885/-the-effect-of-floating-needle-therapy-combined-with-rehabilitation-training-for-the-hand-function-recovery-of-post-stroke-patients
#8
RANDOMIZED CONTROLLED TRIAL
Jiangxia Yang, Hong Xiao
OBJECTIVE: To explore the improvement of hand motion function,spasm and self-care ability of daily life for stroke patients treated with floating-needle combined with rehabilitation training. METHODS: Eighty hand spasm patients of post-stroke within one year after stroke were randomly divided into an observation group and a control group, 40 cases in each one. In the two groups, rehabilitation was adopted for eight weeks,once a day,40 min one time. In the observation group, based on the above treatment and according to muscle fascia trigger point, 2~3 points in both the internal and external sides of forearm were treated with floating-needle...
August 2015: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/26506940/digital-periarterial-sympathectomy-in-the-management-of-post-traumatic-raynaud-syndrome
#9
Ander Letamendia, Javier López-Román, Juan Bustamante-Munguira, Jesús Herreros
OBJECTIVE: Among Basque handball players, the repeated impact of a ball on the palms of their hands hundreds of thousands of times throughout their sporting careers produces Raynaud syndrome. Treating this patient group is complex. Our objective was to assess the efficacy of digital periarterial sympathectomy in this patient group. METHODS: The study included all of the federated amateur and professional Basque handball patients who presented with Raynaud syndrome assessed in the vascular surgery service between January 2005 and December 2012...
February 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/26174511/novel-kif7-missense-substitutions-in-two-patients-presenting-with-multiple-malformations-and-features-of-acrocallosal-syndrome
#10
Sanjin Tunovic, Kristin W Barañano, James A Barkovich, Jonathan B Strober, Leila Jamal, Anne M Slavotinek
We present two children who both had two missense mutations in the Kinesin Family Member 7 (KIF7) gene. A seven year old female with severe developmental delays, failure to thrive and growth retardation, infantile spasms, a cardiac vascular ring and right-sided aortic arch, imperforate anus, hydronephrosis with a right renal cyst, syndactyly and abnormal white matter was a compound heterozygote for c.3365C > G, predicting p.(Ser1122Trp) that was maternally inherited and c.2482G > A, predicting p...
November 2015: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/26162037/reduction-in-high-frequency-hearing-loss-following-technical-modifications-to-microvascular-decompression-for-hemifacial-spasm
#11
Parthasarathy Thirumala, Andrew M Frederickson, Jeffrey Balzer, Donald Crammond, Miguel E Habeych, Yue-Fang Chang, Raymond F Sekula
OBJECT: Microvascular decompression is a safe and effective procedure to treat hemifacial spasm, but the operation poses some risk to the patient's hearing. While severe sensorineural hearing loss across all frequencies occurs at a low rate in experienced hands, a recent study suggests that as many as one-half of patients who undergo this procedure may experience ipsilateral high-frequency hearing loss (HFHL), and as many as one-quarter may experience contralateral HFHL. While it has been suggested that drill-related noise may account for this finding, this study was designed to examine the effect of a number of techniques designed to protect the vestibulocochlear nerve from operative manipulation on the incidence of HFHL...
October 2015: Journal of Neurosurgery
https://www.readbyqxmd.com/read/26037425/malignant-hyperthermia-in-a-young-adolescent-a-case-report
#12
Han Toh, Jagdish Menghraj Shahani, Ayesha Jabeen Ali
A 15-year-old girl developed symptoms suggestive of malignant hyperthermia during a laparoscopic appendicectomy for acute appendicitis. The triad of masseter spasm, hypercarbia and hyperthermia within 30 minutes of exposure to triggering factors was present and was treated successfully with dantrolene. She is among a handful of cases known locally. The problems faced in the post-acute phase included the development of thrombophlebitis due to dantrolene use in our patient, as well as paucity of testing centres for malignant hyperthermia both locally and in the region...
September 2014: National Medical Journal of India
https://www.readbyqxmd.com/read/26004935/angina-pectoris-in-patients-without-flow-limiting-coronary-artery-disease-cardiac-syndrome-x-a-forest-of-a-variety-of-trees
#13
Giuseppe Cocco, Paul Jerie
Coronary heart disease (CHD) represents an important problem worldwide. At present, more women than men are evaluated for CHD and it has been recognized that the prevalence of this pathology in women is at least the same as in men. We have learned that cardiac syndrome X (CSX) is frequent because worldwide each year millions of people (mostly women) with angina pectoris without flow-limiting epicardial pathology are identified. Data from large myocardial infarction registries suggest a 5% to 25% prevalence of cases without flow-limiting coronary pathology...
2015: Cardiology Journal
https://www.readbyqxmd.com/read/25887990/toxicological-studies-of-stem-bark-extract-from-schefflera-barteri-harms-araliaceae
#14
Serge Secco Atsafack, Jules-Roger Kuiate, Raymond Simplice Mouokeu, Martin Luther Koanga Mogtomo, Alembert Tiabou Tchinda, Tamokou Jean De Dieu, Huguette Magnifouet Nana, Rébecca Madeleine Ebelle Etame, Lucie Biyiti, Rosalie Annie Ngono Ngane
BACKGROUND: The use of herbal medicines as complements or alternatives to orthodox medicines has been on the increase. There has been the erroneous belief that these medicines are free from adverse effects. Schefflera barteri is popularly used in the West region of Cameroon for the treatment of various diseases such as diarrhea, spasm, pneumonia and animals bite. Considering the ethnopharmacological relevance of this plant, this study was designed to investigate the possible toxic effects of the stem bark extract of S...
2015: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/25835105/a-functional-study-of-the-esophagus-in-patients-with-non-cardiac-chest-pain-and-dysphagia
#15
Roberto Gullo, Angela Inviati, Piero Luigi Almasio, Valentina Di Paola, Silvia Di Giovanni, Gregorio Scerrino, Gaspare Gulotta, Sebastiano Bonventre
BACKGROUND/AIMS: Nutcracker esophagus and non-specific motility disorders are the main causes of non-cardiac chest pain (NCCP), with gastroesophageal reflux in 60% of cases. Achalasia and diffuse esophageal spasm are the most frequent anomalies described in patients with dysphagia. The goal of this study was to evaluate the occurrence of esophageal body and lower esophageal sphincter motor abnormalities in patients with dysphagia, NCCP, or both. MATERIALS AND METHODS: This study is a retrospective analysis of 716 patients with NCCP and/or dysphagia tested between January 1994 and December 2010...
March 2015: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/25790261/adrenaline-with-lidocaine-for-digital-nerve-blocks
#16
REVIEW
Hemanshu Prabhakar, Santosh Rath, Mani Kalaivani, Neel Bhanderi
BACKGROUND: Surgery on fingers is a common procedure in emergency and day care surgery. Adrenaline combined with lidocaine can prolong digital nerve block and provide a bloodless operating field. Extended postoperative pain relief can reduce the need for analgesics and can facilitate hand rehabilitation. Conventionally, adrenaline is avoided at anatomical sites with end arteries such as digits, penis and pinna because of concerns about arterial spasm, ischaemia and gangrene distal to the site of drug infiltration...
2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/25783935/toxicological-studies-of-stem-bark-extract-from-schefflera-barteri-harms-araliaceae
#17
Serge Secco Atsafack, Jules-Roger Kuiate, Raymond Simplice Mouokeu, Martin Luther Koanga Mogtomo, Alembert Tiabou Tchinda, Tamokou Jean De Dieu, Huguette Magnifouet Nana, Rébecca Madeleine Ebelle Etame, Lucie Biyiti, Rosalie Annie Ngono Ngane
BACKGROUND: The use of herbal medicines as complements or alternatives to orthodox medicines has been on the increase. There has been the erroneous belief that these medicines are free from adverse effects. Schefflera barteri is popularly used in the West region of Cameroon for the treatment of various diseases such as diarrhea, spasm, pneumonia and animals bite. Considering the ethnopharmacological relevance of this plant, this study was designed to investigate the possible toxic effects of the stem bark extract of S...
December 2015: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/25751627/de-novo-loss-or-gain-of-function-mutations-in-kcna2-cause-epileptic-encephalopathy
#18
Steffen Syrbe, Ulrike B S Hedrich, Erik Riesch, Tania Djémié, Stephan Müller, Rikke S Møller, Bridget Maher, Laura Hernandez-Hernandez, Matthis Synofzik, Hande S Caglayan, Mutluay Arslan, José M Serratosa, Michael Nothnagel, Patrick May, Roland Krause, Heidrun Löffler, Katja Detert, Thomas Dorn, Heinrich Vogt, Günter Krämer, Ludger Schöls, Primus E Mullis, Tarja Linnankivi, Anna-Elina Lehesjoki, Katalin Sterbova, Dana C Craiu, Dorota Hoffman-Zacharska, Christian M Korff, Yvonne G Weber, Maja Steinlin, Sabina Gallati, Astrid Bertsche, Matthias K Bernhard, Andreas Merkenschlager, Wieland Kiess, Michael Gonzalez, Stephan Züchner, Aarno Palotie, Arvid Suls, Peter De Jonghe, Ingo Helbig, Saskia Biskup, Markus Wolff, Snezana Maljevic, Rebecca Schüle, Sanjay M Sisodiya, Sarah Weckhuysen, Holger Lerche, Johannes R Lemke
Epileptic encephalopathies are a phenotypically and genetically heterogeneous group of severe epilepsies accompanied by intellectual disability and other neurodevelopmental features. Using next-generation sequencing, we identified four different de novo mutations in KCNA2, encoding the potassium channel KV1.2, in six isolated patients with epileptic encephalopathy (one mutation recurred three times independently). Four individuals presented with febrile and multiple afebrile, often focal seizure types, multifocal epileptiform discharges strongly activated by sleep, mild to moderate intellectual disability, delayed speech development and sometimes ataxia...
April 2015: Nature Genetics
https://www.readbyqxmd.com/read/25669008/impossible-mask-ventilation-after-an-unusually-low-dose-fentanyl-induced-muscle-rigidity-in-a-patient-with-essential-tremor-a-case-report-and-review-of-the-literature
#19
REVIEW
Vassilios Dimitriou, Ioannis Zogogiannis, Despoina Liotiri, Freddie Wambi, Nasser Tawfeeq, Adnan Koumi, Georges Geldhof
Although opioid-induced muscle rigidity occurs more commonly with large doses and rapid administration of the drugs, there is a number of cases reported, where muscle rigidity was experienced with lower doses of opioids. We present and discuss a case of muscle rigidity induced by an unusually low dose of fentanyl as primary agent during induction of anesthesia. A 79 year old male patient, scheduled for hernia repair, and with a preoperative physical examination of slight hand tremor, received a bolus of 100 mcg (1...
October 2014: Middle East Journal of Anesthesiology
https://www.readbyqxmd.com/read/25621693/complex-regional-pain-syndrome-and-acute-carpal-tunnel-syndrome-following-radial-artery-cannulation-a-neurological-perspective-and-review-of-the-literature
#20
REVIEW
Reynaldo P Lazaro
Complex regional pain syndrome (CRPS) associated with acute carpal tunnel syndrome (aCTS) developed in a 38-year-old right-handed man following radial artery cannulation (RAC) during the course of lumbar spine surgery. Inciting events and risk factors that might have led to these complications included: multiple arterial punctures and subsequent hematoma formation, radial artery spasm compounded by aggressive hemostasis, anatomical changes in the wrists related to repetitive manual activities in the workplace, and possible protracted hyperextension of the wrists during perioperative and operative procedure...
January 2015: Medicine (Baltimore)
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