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Cinnamaldehyde

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https://www.readbyqxmd.com/read/28633539/a-survey-on-chemical-constituents-and-indications-of-aromatic-waters-soft-drinks-hydrosols-used-in-persian-nutrition-culture-and-folk-medicine-for-neurological-disorders-and-mental-health
#1
Azadeh Hamedi, Ardalan Pasdaran, Zahra Zebarjad, Mahmoodreza Moein
In Persian nutrition culture, drinking aromatic waters (hydrosols, distillate) has a long history as functional beverages or therapeutic remedies. The co-distilled water with essential oils, which contains partial amounts of more water-soluble volatile compounds are diluted and used as beverages. Since the solubility of volatile components is different in water, the overall composition, and thus the biological activities of aromatic waters seem to be different from the essential oils they were co-distilled with...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/28627304/the-effects-of-selected-phytochemicals-on-biofilm-formed-by-five-methicillin-resistant-staphylococcus-aureus
#2
Barbara Kot, Kamila Wierzchowska, Agata Grużewska, Dzmitry Lohinau
The aim of this study was to evaluate the ability of 0.1% thyme oil (TO), trans-cinnamaldehyde (TC), ferulic acid (FA), p-coumaric acid (p-CA), caffeic acid (CA), lavender essential oil (LO), geranium essential oil (GO) and tee tree oil (TTO) to control biofilms formed by methicillin-resistant Staphylococcus aureus (MRSA) strains. Depending on the strains, TO reduced 59.7-85% of biofilm mass, while TC 52.9-82.4% after 48 h of treatment. Reduction of metabolic activity of biofilms in ranges 79.3-86% and 85...
June 18, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28620947/effect-of-applying-cinnamaldehyde-incorporated-in-wax-on-green-mold-decay-in-citrus-fruits
#3
Xiaofang Duan, Qiuli OuYang, Nengguo Tao
BACKGROUND: Green mold caused by Penicillium digitatum is the most damaging postharvest diseases of citrus fruit. Cinnamaldehyde (CA) is a food additive that has potential use in controlling postharvest disease of fruits and vegetables. In this study, the effectiveness of wax with CA (WCA) in controlling Ponkan (Citrus reticulata Blanco) green mold was investigated. RESULTS: The mycelial growth of P. digitatum was inhibited by CA in a dose-dependent manner. The minimum inhibitory concentration and minimum fungicidal concentration (MFC) were both 0...
June 16, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28605202/supramolecular-construction-of-an-aldehyde-cyclobutane-via-the-solid-state-combining-reversible-imine-formation-and-metal-organic-self-assembly
#4
Shalisa M Oburn, Dale C Swenson, S V Santhana Mariappan, Leonard R MacGillivray
A combination of metal-organic self-assembly and reversible imine formation is used to achieve an organic synthesis via the solid state. Imine bond formation is employed to install a pyridyl to the alkene trans-cinnamaldehyde while Ag(I) ions are used in a second step to assemble the pyridyl-functionalized alkene into a geometry in the solid state for an intermolecular [2 + 2] photodimerization. The alkene undergoes the cycloaddition reaction via a 1D coordination polymer to generate a pyridyl-functionalized cyclobutane stereoselectively and in quantitative yield...
June 15, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28600870/selective-catalytic-performances-of-noble-metal-nanoparticle-mof-composites-the-concomitant-effect-of-aperture-size-and-structural-flexibility-of-mof-matrices
#5
Luning Chen, Wenwen Zhan, Huihuang Fang, Zhenmin Cao, Chaofan Yuan, Zhaoxiong Xie, Qin Kuang, Lansun Zheng
Noble metal nanoparticles embedded in metal organic frameworks (MOFs) are new composite catalysts with enhanced or novel properties compared to the pristine counterparts. In the past years, to determine the role of MOFs during catalytic process, most of studies focus on the confinement effect of MOFs, but ignore the structural flexibility of MOFs. In this paper, we use two composite catalysts, Pt@ZIF-8 [Zn(mIM)2, mIM = 2-methyl imidazole] with flexible structure and Pt@ZIF-71 [Zn(DClIM)2, DClIM = 4,5-dichloroimidazole] with rigid structure, and hydrogenation of cinnamaldehyde as model reaction, to show the confinement effect and the structure flexibility of MOF matrices on the catalytic performance of composite catalysts...
June 10, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28585246/confining-the-nucleation-of-pt-to-in-situ-form-pt-enriched-cage-ceo2-core-shell-nanostructure-as-excellent-catalysts-for-hydrogenation-reactions
#6
Songyan Song, Xianchun Liu, Junqi Li, Jing Pan, Fan Wang, Yan Xing, Xiao Wang, Xiaogang Liu, Hongjie Zhang
Ultrathin (Pt-enriched cage)@CeO2 core@shell nanostructures are successfully fabricated via a facile hard-template method. It is found that the usage of Pd@Ag@CeO2 bi-metallic core@shell nanostructure as the hard template plays an important role in avoiding the independent nucleation of Pt metal during the galvanic replacement process between K2 PtCl4 and Ag components. This unique core@shell samples show extraordinary activity and selectivity for the cinnamaldehyde hydrogenation reaction. It can achieve over 95% conversion with 87% selectivity of hydrocinnamaldehyde in 5 h under 1 atm H2 pressure...
June 6, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28560053/volatiles-profiling-in-ceratonia-siliqua-carob-bean-from-egypt-and-in-response-to-roasting-as-analyzed-via-solid-phase-microextraction-coupled-to-chemometrics
#7
Mohamed A Farag, Dina M El-Kersh
Ceratonia siliqua is a legume tree of considerable commercial importance for the flavor and sweets industry cultivated mostly for its pods nutritive value and or several health benefits. Despite extensive studies on C. siliqua pod non-volatile metabolites, much less is known regarding volatiles composition which contributes to the flavor of its many food products. To gain insight into C. siliqua aroma, 31 volatile constituents from unroasted and roasted pods were profiled using headspace solid-phase micro extraction (HD-SPME) analyzed via quadruple mass spectrometer followed by multivariate data analyses...
July 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/28559210/cinnamaldehyde-in-diabetes-a-review-of-pharmacology-pharmacokinetics-and-safety
#8
REVIEW
Ruyuan Zhu, Haixia Liu, Chenyue Liu, Lili Wang, Rufeng Ma, Beibei Chen, Lin Li, Jianzhao Niu, Min Fu, Dongwei Zhang, Sihua Gao
Cinnamaldehyde, one of the active components derived from Cinnamon, has been used as a natural flavorant and fragrance agent in kitchen and industry. Emerging studies have been performed over the past decades to evaluate its beneficial role in management of diabetes and its complications. This review highlights recent advances of cinnamaldehyde in its glucolipid lowering effects, its pharmacokinetics, and its safety by consulting the Pubmed, China Knowledge Resource Integrated, China Science and Technology Journal, National Science and Technology Library, Wanfang Data, and the Web of Science Databases...
May 27, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/28556537/insecticidal-activities-of-their-components-derived-from-the-essential-oils-of-cinnamomum-sp-barks-and-against-ricania-sp-homoptera-ricaniidae-a-newly-recorded-pest
#9
Ye-Jin Jeon, Sang-Guei Lee, Young-Cheol Yang, Hoi Seon Lee
BACKGROUND: Insecticidal activities of Cinnamomum cassia and C. zeylanicum oils and their components are not known against Ricania sp. Insecticidal activities of major components derived from C. cassia and C. zeylanicum oils were examined in spray and leaf dipping bioassays against Ricania sp. nymphs and adults. RESULTS: LC50 value of C. cassia and C. zeylanicum oils was 37.66 and 72.62 mg/L, respectively, in the leaf dipping bioassays against Ricania sp. nymphs, and 77...
May 27, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28534638/diastereoselective-3-2-vs-4-2-cycloadditions-of-nitroprolinates-with-%C3%AE-%C3%AE-unsaturated-aldehydes-and-electrophilic-alkenes-an-example-of-total-periselectivity
#10
Verónica Selva, Olatz Larrañaga, Luis M Castelló, Carmen Nájera, José M Sansano, Abel de Cózar
Diastereoselective multicomponent reactions of enantioenriched 4-nitroprolinates, obtained by enantiocatalyzed 1,3-dipolar cycloaddition (1,3-DC) of imino esters and nitroalkenes, with α,β-unsaturated aldehydes and electrophilic alkenes proceed with total periselectivity depending on the structure of the aldehyde employed. This process evolves through a [3 + 2] 1,3-DC when cinnamaldehyde is used in the presence of an azomethine ylide, giving the corresponding highly substituted pyrrolizidines with endo selectivity...
June 7, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28526768/direct-comparison-of-the-enzymatic-characteristics-and-superoxide-production-of-the-four-aldehyde-oxidase-enzymes-present-in-mouse
#11
Gokhan Kucukgoze, Mineko Terao, Enrico Garattini, Silke Leimkuhler
Aldehyde oxidases (AOXs) are molybdoflavoenzymes with an important role in the metabolism and detoxification of heterocyclic compounds and aliphatic as well as aromatic aldehydes. The enzymes use oxygen as the terminal electron acceptor and produce reduced oxygen species during turnover. Four different enzymes, mAOX1, mAOX3, mAOX4 and mAOX2, which are the products of distinct genes, are present in the mouse. A direct and simultaneous comparison of the enzymatic properties and characteristics of the four enzymes has never been performed...
May 19, 2017: Drug Metabolism and Disposition: the Biological Fate of Chemicals
https://www.readbyqxmd.com/read/28525761/impact-of-bioactive-packaging-systems-based-on-evoh-films-and-essential-oils-in-the-control-of-aflatoxigenic-fungi-and-aflatoxin-production-in-maize
#12
Eva M Mateo, José V Gómez, Irene Domínguez, Jose V Gimeno-Adelantado, Rufino Mateo-Castro, Rafael Gavara, Misericordia Jiménez
Aspergillus flavus and A. parasiticus are the most common fungal species associated with aflatoxin (AF) contamination of cereals, especially maize, and other agricultural commodities. AFB1, the most frequent and toxic metabolite, is a powerful hepatotoxic, teratogenic and mutagenic compound. Effective strategies to control these fungal species and AFs in food and feed are required. Active packaging film containing essential oils (EO) is one of the most innovative food packaging concepts. In this study, ethylene-vinyl alcohol (EVOH) copolymer films incorporating EO from Origanum vulgare (ORE), Cinnamomum zeylanicum (CIN) or their major active constituents, carvacrol (CAR) and cinnamaldehyde (CINHO), respectively, were developed and assayed to control growth of A...
May 11, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28521511/effects-of-adaptation-to-carvacrol-on-staphylococcus-aureus-in-the-planktonic-and-biofilm-phases
#13
Antonia Nostro, Andreana Marino, Giovanna Ginestra, Luigina Cellini, Mara Di Giulio, Giuseppe Bisignano
The effect of exposure to sub-minimum inhibitory concentrations of carvacrol, for either 3-10 days, on direct (carvacrol) or cross-protection (cinnamaldehyde, eugenol, antibiotics) and the influence on planktonic and biofilm growth of four Staphylococcus aureus strains were reported. The sequential exposure to carvacrol resulted in a direct protection that was more evident in two of the four strains after 10 days. No significant cross-protection against cinnamaldehyde, eugenol and antibiotics was detected...
May 18, 2017: Biofouling
https://www.readbyqxmd.com/read/28507116/toxic-electrophiles-induce-expression-of-the-multi-drug-efflux-pump-mexef-oprn-in-pseudomonas-aeruginosa-through-a-novel-transcriptional-regulator-cmra
#14
Paulo Juarez, Katy Jeannot, Patrick Plésiat, Catherine Llanes
The multidrug efflux system MexEF-OprN is produced at low levels in wild-type strains of Pseudomonas aeruginosa. However, mutational alteration of gene mexS results in constitutive overexpression of the pump along with an increased resistance of the bacterium to chloramphenicol, fluoroquinolones and trimethoprim. In this study, analysis of in vitro selected chloramphenicol-resistant clones of strain PA14 led to the identification of a new class of mutants (called nfxC2) exhibiting alterations in a so far uncharacterized gene, PA14_38040 (homolog of PA2047 in strain PAO1)...
May 15, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28504167/antibacterial-and-antioxidative-activity-of-o-amine-functionalized-chitosan
#15
Tamer M Tamer, Mohamed A Hassan, Ahmed M Omer, Katarína Valachová, Mohamed S Mohy Eldin, Maurice N Collins, Ladislav Šoltés
Cinnamaldehyde was immobilized to O-amine functionalized chitosan via a coupling reaction. Fourier transform infrared spectroscopy confirmed N-cinnamyl substitution. Wetting analyses demonstrate more hydrophobicity in the N-cinnamyl substituted O-amine functionalized chitosan compared to chitosan or unsubstituted O-amine functionalized chitosan. Thermal gravimetric analysis and differential scanning calorimetry demonstrates that the prepared N-cinnamyl substituted O-amine functionalized chitosan exhibits higher thermostability than unmodified chitosan at temperatures in which polysaccharides are commonly stored and utilised...
August 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28495856/flavored-e-cigarette-liquids-and-cinnamaldehyde-impair-respiratory-innate-immune-cell-function
#16
Phillip Wayne Clapp, Erica Ann Pawlak, Justin Trevor Lackey, James Edward Keating, Steven L Reeber, Gary L Glish, Ilona Jaspers
Innate immune cells of the respiratory tract are the first line of defense against pathogenic and environmental insults. Failure of these cells to perform their immune functions leaves the host susceptible to infection, and may contribute to impaired resolution of inflammation. While combustible tobacco cigarettes have been shown to suppress respiratory immune cell function, the effects of flavored electronic cigarette liquids (e-liquids) and individual flavoring agents on respiratory immune cell responses are unknown...
May 11, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/28489336/antimicrobial-activity-of-natural-products-against-clostridium-difficile-in-vitro
#17
Niloufar Roshan, Thomas V Riley, Katherine A Hammer
AIMS: To investigate the antimicrobial activity of various natural products against C. difficile in vitro. METHODS AND RESULTS: The antibacterial activity of 20 natural products was determined by the agar well diffusion and broth microdilution assays against four C. difficile strains, three comparator organisms and four gastrointestinal commensal organisms. Of the raw natural products, garlic juice had the highest activity. The most active processed products were peppermint oil and the four pure compounds trans-cinnamaldehyde, allicin, menthol and zingerone...
May 10, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28487683/trans-cinnamaldehyde-carvacrol-and-eugenol-reduce-campylobacter-jejuni-colonization-factors-and-expression-of-virulence-genes-in-vitro
#18
Abhinav Upadhyay, Komala Arsi, Basanta R Wagle, Indu Upadhyaya, Sandip Shrestha, Ann M Donoghue, Dan J Donoghue
Campylobacter jejuni is a major foodborne pathogen that causes severe gastroenteritis in humans characterized by fever, diarrhea, and abdominal cramps. In the human gut, Campylobacter adheres and invades the intestinal epithelium followed by cytolethal distending toxin mediated cell death, and enteritis. Reducing the attachment and invasion of Campylobacter to intestinal epithelium and expression of its virulence factors such as motility and cytolethal distending toxin (CDT) production could potentially reduce infection in humans...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28450018/interaction-between-natural-antioxidants-derived-from-cinnamon-and-cocoa-in-binary-and-complex-mixtures
#19
Dimas Rahadian Aji Muhammad, Danar Praseptiangga, Davy Van de Walle, Koen Dewettinck
Cinnamon and cocoa are known to be valuable sources of bioactive phytochemicals, mainly the polyphenols. This paper investigates the potential antioxidant activity of cinnamon and cocoa extract and the interaction of their mixtures by various in vitro tests. Moreover, the combination effect of their constituents in a binary mixture was studied. Two representative active compounds of chocolate (epicatechin, catechin) were combined with seven of cinnamon (gallic acid, tannic acid, quercetin, sinapic acid, cinnamic acid, eugenol and cinnamaldehyde) in multilevel ratios...
September 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28449595/pharmaceutical-perspectives-of-spices-and-condiments-as-alternative-antimicrobial-remedy
#20
Savita P D'Souza, Suvarna V Chavannavar, B Kanchanashri, S B Niveditha
Medicinal values of spices and condiments are being revived by biologists through in vitro and in vivo trials providing evidence for its antimicrobial activities. The essential oils and extracts of spices like black pepper, cloves, cinnamon, and nutmeg contain active compounds like piperine, eugenol, cinnamaldehyde, and lignans. Similarly, condiments like coriander, black cumin, turmeric, garlic, and ginger are recognized for constituents like linalool, thymoquinones, curcumin, allicin, and geranial respectively...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
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