Read by QxMD icon Read


Behjat Javadi
Cancer is the second leading cause of death with profound socio-economic consequences worldwide. Growing evidence suggests the crucial role of diet on cancer prevention and treatment. In Traditional Persian Medicine (TPM) there is a major focus on contribution of special diet and foods to cancer management. In the present article, the cytotoxic and antitumor activities of several food items including plants and animal products recommended by TPM as anticancer agents are discussed. Strong evidence supports the anticancer effects of beetroot (Beta vulgris) and its major compound betanin, cinnamon and cinnamaldehyde, barley (H...
March 15, 2018: Nutrition and Cancer
Md Shahadat Hossan, Hassan Jindal, Sarah Maisha, Chandramathi Samudi Raju, Shamala Devi Sekaran, Veeranoot Nissapatorn, Fatima Kaharudin, Lim Su Yi, Teng Jin Khoo, Mohammed Rahmatullah, Christophe Wiart
CONTEXT: The resistance of bacteria to antibiotics is raising serious concern globally. Asian medicinal plants could improve the current treatment strategies for bacterial infections. The antibacterial properties of medicinal plants used by the Khyang tribe in Bangladesh have not been investigated. OBJECTIVE: The present study examines the antibacterial properties of 18 medicinal plants used by the Khyang tribe in day-to-day practice against human pathogenic bacteria...
December 2018: Pharmaceutical Biology
Saud Alanazi, Maryam Alnoman, Saeed Banawas, Ryoichi Saito, Mahfuzur R Sarker
C. perfringens type A is the causative agent of C. perfringens type A food poisoning (FP) and non-food-borne (NFB) human gastrointestinal diseases. Due to its ability to form highly heat-resistant spores, it is of great interest to develop strategies alternative to thermal processing to inactivate C. perfrinegens. Thus, in this study we evaluated the inhibitory effects of essential oil constituents (EOCs) (cinnamaldehyde, eugenol, allyl isothiocyanate (AITC), and carvacrol) against germination, outgrowth and vegetative growth of spores of C...
August 2018: Food Microbiology
Wenping Hu, Kuo Yuan, Tianqun Song, Dawei Wang, Xiaotao Zhang, Xiong Gao, Ye Zou, Huanli Dong, ZHiyong Tang
As for heterogeneous catalysis, the activity and selectivity are two key factors for evaluating catalysts. Metal-organic frameworks (MOFs) as selectivity regulators for catalytic reaction have attracted much attention, especially MOFs and metal nanoparticles (NPs) shelled structures, e.g., MOFs@NPs@MOFs. Nevertheless, the hydrophilic MOFs shell is challenging to gather hydrophobic reactants. Here, we innovate a new and viable approach to solve this problem. By employing conjugated micro- and mesoporous polymers with iron(Ⅲ) porphyrin (FeP-CMPs) as the new shell, MIL-101@Pt@FeP-CMP was fabricated firstly, which not only is hydrophobic and porous to enrich reactants, but also possesses iron sites to activate C=O bond and thereby regulate the selectivity for cinnamyl alcohol in hydrogenation of cinnamaldehyde...
March 6, 2018: Angewandte Chemie
J A Pempek, E Holder, K L Proudfoot, M Masterson, G Habing
The inherent disease susceptibility of veal calves results in frequent antimicrobial use. Improvements in antimicrobial stewardship necessitate alternative therapies to improve calf health and growth, while reducing the need for antimicrobials important to human health. This study investigated the effect of 2 alternative therapies, lactoferrin (an iron-binding protein found in colostrum) and cinnamaldehyde (an essential oil of the cinnamon plant) on growth, disease incidence, and mortality risk in special-fed veal calves...
February 28, 2018: Journal of Dairy Science
Vinod Vijayan, Avik Mazumder
Cinnamon (Cinnamomum cassia) is an important spice which is widely consumed in the Indian subcontinent as well as in several other parts of the world. In the present study, NMR spectroscopy showed the presence of cinnamaldehyde to be the major component of the bark. The possible mutagenic effects of cinnamon bark ethanolic extract (CEE, 0.01-1 mg/plate) cinnamon oil (CNO, 0.125-1 mg/plate), and its active component cinnamadehyde (CLD, 0.125-1 mg/plate) were evaluated. Antimutagenic activity of CEE, CNO, and CLD was also tested against various food borne mutagens (heterocyclic amines and aflatoxin B1 (AFB1)) and sodium azide (SA) using Ames assay...
February 26, 2018: Drug and Chemical Toxicology
Julie Charpentier, Roger Emter, Heinz Koch, Dominique Lelièvre, Xavier Pannecoucke, Samuel Couve-Bonnaire, Andreas Natsch, Agnes Bombrun
A series of three α- and three β-fluorinated representatives of the family of cinnamate-derived odorants (cinnamaldehyde (1), cinnamyl alcohol (2) and ethyl cinnamate (3)) used as fragrance ingredients is described. Olfactive evaluation shows that the fluorinated compounds exhibit a similar odor profile to their parent compounds, but the olfactive detection thresholds are clearly higher. In vitro evaluation of the skin sensitizing properties with three different assays indicates that α-fluorination of Michael acceptor systems 1 and 3 slightly improves the skin sensitization profile...
February 24, 2018: Chemistry & Biodiversity
Fei Liu, Furkan Türker Saricaoglu, Roberto J Avena-Bustillos, David F Bridges, Gary R Takeoka, Vivian C H Wu, Bor-Sen Chiou, Delilah F Wood, Tara H McHugh, Fang Zhong
Cinnamaldehyde, a natural preservative that can non-specifically deactivate foodborne pathogens, was successfully incorporated into fish skin gelatin (FSG) solutions and blow spun into uniform nanofibers. The effects of cinnamaldehyde ratios (5-30%, w / w FSG) on physicochemical properties of fiber-forming emulsions (FFEs) and their nanofibers were investigated. Higher ratios resulted in higher values in particle size and viscosity of FFEs, as well as higher values in diameter of nanofibers. Loss of cinnamaldehyde was observed during solution blow spinning (SBS) process and cinnamaldehyde was mainly located on the surface of resultant nanofibers...
February 22, 2018: International Journal of Molecular Sciences
Nawasit Chotsaeng, Chamroon Laosinwattana, Patchanee Charoenying
Thirty-seven commercial aldehydes containing aliphatic chains and aromatic rings as well as heteroaromatic rings were evaluated for their inhibitory activities against Chinese amaranth ( Amaranthus tricolor L.) and barnyardgrass ( Echinochloa crus-galli (L.) Beauv). Polysorbate 80 (Tween® 80) was used as a surfactant and the research was preliminarily conducted at 400 μM of all aldehydes. Among these aldehydes, ( E )-cinnamaldehyde ( 7 ) showed the greatest inhibitory effect on seed germination, shoot and root growth of Chinese amaranth by 54...
February 21, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Xing Yuan, Lin Han, Peng Fu, Huawu Zeng, Chao Lv, Wanlin Chang, R Scott Runyon, Momoko Ishii, Liwen Han, Kechun Liu, Taiping Fan, Weidong Zhang, Runhui Liu
The bark of Cinnamomum cassia (C. cassia) has been used for the management of coronary heart disease (CHD) and diabetes mellitus. C. cassia may target the vasculature, as it stimulates angiogenesis, promotes blood circulation and wound healing. However, the active components and working mechanisms of C. cassia are not fully elucidated. The Shexiang Baoxin pill (SBP), which consists of seven medicinal materials, including C. cassia etc., is widely used as a traditional Chinese patent medicine for the treatment of CHD...
February 20, 2018: Laboratory Investigation; a Journal of Technical Methods and Pathology
Caio Átila Prata Bezerra Souza, Breytiner Amaro de Oliveira, Sacha Aubrey Alves Rodrigues Santos, Francisco Lucas Alves Batista, Francisco Regivânio Nascimento Andrade, Eugênio Januário Ramos Neto, José de Maria Albuquerque de Melo Júnior, Francisco Rogenio da Silva Mendes, Lana Karine Vasconcelos Barroso, Kirley Marques Canuto, Francisco Ernani Alves Magalhães, Angelo Roncalli Alves E Silva, Wladimir Ronald Lobo Farias, Adriana Rolim Campos
This study aimed to evaluate the antinociceptive effect of sulphated polysaccharide from the marine algae Hypnea pseudomusciformis (PLS) using rodent models of orofacial pain. Acute pain was induced by formalin, capsaicin, cinnamaldehyde, acidified saline or glutamate (cutaneous modes) and hypertonic saline (corneal model). In one experiment, animals were pretreated with ruthenium red, glibenclamide, naloxone, L-NAME, methylene blue or ketamine to investigate the mechanism of antinociception. In another experiment, animals pretreated with PLS or saline were submitted to the temporomandibular joint formalin test...
February 19, 2018: Inflammopharmacology
P Suwanamornlert, S Sangchote, W Chinsirikul, A Sane, V Chonhenchob
The aim of this study was to find alternatives to conventional synthetic fungicides to control postharvest decay of longan fruit. The antifungal potential of thymol, carvacrol and trans-cinnamaldehyde was evaluated against four major longan pathogens, Lasiodiplodia spp., Phomopsis spp., Pestalotiopsis spp. and Geotrichum candidum, using vapor phase and direct contact methods. The vapor phase of all active compounds was more effective on fungal growth than direct contact. A volatile vapor of thymol and carvacrol had strong antifungal activity against the tested fungi, exhibiting minimum inhibitory concentration (MIC) in the range of 40 to 80 mg/L air; trans-cinnamaldehyde showed the least efficiency, with MIC ranging from 80 to 160 mg/L air for G...
February 10, 2018: International Journal of Food Microbiology
Sang-Oh Lee, Kyoung-Lyong An, Seung-Rim Shin, Kun Jun, Mergu Naveen, Young-A Son
We report the design and synthesis of a novel chemosensor (Rh6G-Cin) rhodamine-based indicator for selective detection of Zn2+ ion. Rh6G-Cin displayed high selectivity towards Zn2+ from various metal ions, including Ca2+, Ag+, Cd2+, Co2+, Cu2+, Al3+, Zn2+, Cr3+, Ba2+, Fe2+, Fe3+, Gd3+, Hg2+, Mg2+, Mn2+, Nd3+, Pb2+, Sr2+ and Ni2+, and the resultant complex is [Rh6G-Cin-Zn2+]. The obvious change from colorless to pink upon the addition of Zn2+ could make it a suitable "naked eye" indicator for Zn2+...
August 1, 2018: Journal of Nanoscience and Nanotechnology
Zinnat Shahina, Amira M El-Ganiny, Jessica Minion, Malcolm Whiteway, Taranum Sultana, Tanya E S Dahms
Background: Cinnamon ( Cinnamomum zeylanicum) bark extract exhibits potent inhibitory activity against Candida albicans but the antifungal mechanisms of this essential oil remain largely unexplored. Results: We analyzed the impact of cinnamon bark oil on C. albicans RSY150, and clinical strains isolated from patients with candidemia and candidiasis. The viability of RSY150 was significantly compromised in a dose dependent manner when exposed to cinnamon bark oil, with extensive cell surface remodelling at sub inhibitory levels (62...
2018: Fungal Biology and Biotechnology
Itay Gonda, Rachel Davidovich-Rikanati, Einat Bar, Shery Lev, Pliaa Jhirad, Yuval Meshulam, Guy Wissotsky, Vitaly Portnoy, Joseph Burger, Arthur A Schaffer, Yaakov Tadmor, James J Giovannoni, Zhangjun Fei, Aaron Fait, Nurit Katzir, Efraim Lewinsohn
Studies on the active pathways and the genes involved in the biosynthesis of L-phenylalanine-derived volatiles in fleshy fruits are sparse. Melon fruit rinds converted stable-isotope labeled L-phe into more than 20 volatiles. Phenylpropanes, phenylpropenes and benzenoids are apparently produced via the well-known phenylpropanoid pathway involving phenylalanine ammonia lyase (PAL) and being (E)-cinnamic acid a key intermediate. Phenethyl derivatives seemed to be derived from L-phe via a separate biosynthetic route not involving (E)-cinnamic acid and PAL...
February 12, 2018: Phytochemistry
Tingting Li, Dangfeng Wang, Nan Liu, Yan Ma, Ting Ding, Yongchao Mei, Jianrong Li
Pseudomonas fluorescens, an important food spoiling bacteria, uses quorum sensing to control biofilm formation and motility. To date, only a few compounds targeting the LuxR-based quorum sensing system of P. fluorescens have been identified. In the present study, the quorum sensing inhibitory effect of cinnamaldehyde at sublethal concentrations was investigated in terms of inhibition of the extracellular protease, biofilm formation, and swimming and swarming motility. The total volatile basic nitrogen value was also measured to evaluate the effect of cinnamaldehyde on quality preservation of turbot fillets stored at 4 ± 1 °C for 15 days...
February 1, 2018: International Journal of Food Microbiology
Andrea Tarazona, José V Gómez, Rafael Gavara, Rufino Mateo-Castro, José V Gimeno-Adelantado, Misericordia Jiménez, Eva M Mateo
Aspergillus steynii and Aspergillus tubingensis are possibly the main ochratoxin A (OTA) producing species in Aspergillus section Circumdati and section Nigri, respectively. OTA is a potent nephrotoxic, teratogenic, embryotoxic, genotoxic, neurotoxic, carcinogenic and immunosuppressive compound being cereals the first source of OTA in the diet. In this study bioactive ethylene-vinyl alcohol copolymer (EVOH) films containing cinnamaldehyde (CINHO), linalool (LIN), isoeugenol (IEG) or citral (CIT) which are major components of some plant essential oils (EOs) were produced and tested against A...
February 3, 2018: International Journal of Food Microbiology
Shiowshuh Sheen, Chi-Yun Huang, Rommel Ramos, Shih-Yung Chien, O Joseph Scullen, Christopher Sommers
Pathogenic Escherichia coli, intestinal (O157:H7) as well as extraintestinal types (for example, Uropathogenic E. coli [UPEC]) are commonly found in many foods including raw chicken meat. The resistance of E. coli O157:H7 to UPEC in chicken meat under the stresses of high hydrostatic Pressure (HHP, also known as HPP-high pressure processing) and trans-cinnamaldehyde (an essential oil) was investigated and compared. UPEC was found slightly less resistant than O157:H7 in our test parameter ranges. With the addition of trans-cinnamaldehyde as an antimicrobial to meat, HPP lethality enhanced both O157:H7 and UPEC inactivation...
February 7, 2018: Journal of Food Science
Ishrat Husain, Rumana Ahmad, Anu Chandra, Syed Tasleem Raza, Yogeshwer Shukla, Farzana Mahdi
ETHNOPHARMACOLOGICAL RELEVANCE: India being a multicultural nation, every region of the country offers a distinct culinary flavor and taste. These flavours are attributed to spices and condiments which form the mainstay of Indian cuisine. Most of these spices and condiments are derived from various biodiversity hotspots in India and form the crux of India's multidiverse and multicultural cuisine. Apart from their varying aromas, flavors and tastes, these spices and condiments are known to possess several medicinal properties also...
February 2, 2018: Journal of Ethnopharmacology
Shih-Chieh Lee, Shih-Yun Wang, Chien-Chun Li, Cheng-Tzu Liu
Cinnamomum osmophloeum Kanehira is a Taiwan native plant that belongs to genus Cinnamomum and is also known as pseudocinnamomum or indigenous cinnamon. Its leaf is traditionally used by local people in cooking and as folk therapy. We previously demonstrated the chemical composition and anti-inflammatory effect of leaf essential oil of Cinnamomum osmophloeum Kanehira of linalool chemotype in streptozotocin-induced diabetic rats and on endotoxin-injected mice. The aim of the present study is to evaluate whether cinnamaldehyde and linalool the active anti-inflammatory compounds in leaf essential oil of Cinnamomum osmophloeum Kanehira...
January 2018: Journal of Food and Drug Analysis
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"