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Radiation-oncology

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https://www.readbyqxmd.com/read/29027125/a-survey-of-modulated-radiotherapy-use-in-australia-new-zealand-in-2015
#1
Jeffrey Barber, Philip Vial, Paul White, Nick Menzies, Shrikant Deshpande, Regina Bromley, Nick Bennie, Shan Yau, Kristie Harrison
A survey of radiation oncology medical physics departments across Australia and New Zealand was conducted to assess the usage, commissioning and quality assurance of modulated radiotherapy techniques such as IMRT and VMAT. Survey responses were collected in April-May 2015 to snapshot current practice and historical implementation. The survey asked 142 questions, and is the most detailed survey of its kind published to date. Analysis of results at overall department level, as well as sub-analysis for different equipment and techniques in use, was performed...
October 12, 2017: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/28991813/using-discrete-event-simulation-to-promote-quality-improvement-and-efficiency-in-a-radiation-oncology-treatment-center
#2
Robin M Famiglietti, Emily C Norboge, Valentine Boving, James R Langabeer, Thomas A Buchholz, Osama Mikhail
BACKGROUND: To meet demand for radiation oncology services and ensure patient-centered safe care, management in an academic radiation oncology department initiated quality improvement efforts using discrete-event simulation (DES). Although the long-term goal was testing and deploying solutions, the primary aim at the outset was characterizing and validating a computer simulation model of existing operations to identify targets for improvement. METHODS: The adoption and validation of a DES model of processes and procedures affecting patient flow and satisfaction, employee experience, and efficiency were undertaken in 2012-2013...
October 2017: Quality Management in Health Care
https://www.readbyqxmd.com/read/28990370/importance-of-quality-in-radiation-oncology
#3
EDITORIAL
Farshad Foroudi, Tomas Kron
No abstract text is available yet for this article.
October 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/28989910/clinical-implications-of-tigrt-algorithm-for-external-audit-in-radiation-oncology
#4
Daryoush Shahbazi-Gahrouei, Mohsen Saeb, Shahram Monadi, Iraj Jabbari
BACKGROUND: Performing audits play an important role in quality assurance program in radiation oncology. Among different algorithms, TiGRT is one of the common application software for dose calculation. This study aimed to clinical implications of TiGRT algorithm to measure dose and compared to calculated dose delivered to the patients for a variety of cases, with and without the presence of inhomogeneities and beam modifiers. MATERIALS AND METHODS: Nonhomogeneous phantom as quality dose verification phantom, Farmer ionization chambers, and PC-electrometer (Sun Nuclear, USA) as a reference class electrometer was employed throughout the audit in linear accelerators 6 and 18 MV energies (Siemens ONCOR Impression Plus, Germany)...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28988660/improving-the-quality-of-radiation-oncology-10years-experience-of-quatro-audits-in-the-iaea-europe-region
#5
Joanna Izewska, Mary Coffey, Pierre Scalliet, Eduardo Zubizarreta, Tania Santos, Ioannis Vouldis, Peter Dunscombe
BACKGROUND AND PURPOSE: The IAEA has developed a methodology for comprehensive quality audits of radiotherapy practices called Quality Assurance Team for Radiation Oncology (QUATRO). This study explores the factors that impacted quality of care among QUATRO audited centres in the IAEA Europe Region. MATERIALS AND METHODS: The 31 QUATRO reports collected over 10years include extensive data describing the quality of radiotherapy at the audited centres. A coding key was developed to aggregate and review these data in terms of recommendations for improvement and positive findings (commendations)...
October 5, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28982924/handbook-of-supportive-and-palliative-radiation-oncology
#6
(no author information available yet)
No abstract text is available yet for this article.
October 2017: Anticancer Research
https://www.readbyqxmd.com/read/28980444/fostering-a-culture-of-research-within-a-clinical-radiation-oncology-department
#7
Mary-Claire Hanlon, Joanna Ludbrook, Karen Jovanovic, Peter Greer, Jarad Marcus Martin
INTRODUCTION: Support and investment in increasing a research-active culture in clinical practice needs to be translated at the department and hospital levels as well as regional, state and national levels. We aimed to improve the research culture of our department, to enable more clinical staff to become more research competent and research active. METHODS: We describe and discuss the appointment of a Director of Research and a Research Coordinator into our already-research-active department and the interactions at the research-clinical interface...
October 5, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/28975081/radiotherapy-for-oligometastatic-lung-cancer
#8
REVIEW
Derek P Bergsma, Joseph K Salama, Deepinder P Singh, Steven J Chmura, Michael T Milano
Non-small cell lung cancer (NSCLC) typically presents at an advanced stage, which is often felt to be incurable, and such patients are usually treated with a palliative approach. Accumulating retrospective and prospective clinical evidence, including a recently completed randomized trial, support the existence of an oligometastatic disease state wherein select individuals with advanced NSCLC may experience historically unprecedented prolonged survival with aggressive local treatments, consisting of radiotherapy and/or surgery, to limited sites of metastatic disease...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28974857/a-phantom-study-on-fetal-dose-reducing-factors-in-pregnant-patients-with-breast-cancer-during-radiotherapy-treatment
#9
Akın Öğretici, Aydın Çakır, Uğur Akbaş, Canan Köksal, Ümmühan Kalafat, Makbule Tambaş, Hatice Bilge
PURPOSE: This study aims to investigate the factors that reduce fetal dose in pregnant patients with breast cancer throughout their radiation treatment. Two main factors in a standard radiation oncology center are considered as the treatment planning systems (TPSs) and simple shielding for intensity modulated radiation therapy technique. MATERIALS AND METHODS: TPS factor was evaluated with two different planning algorithms: Anisotropic analytical algorithm and Acuros XB (external beam)...
July 2017: Journal of Medical Physics
https://www.readbyqxmd.com/read/28969706/improved-plan-quality-with-automated-radiotherapy-planning-for-whole-brain-with-hippocampus-sparing-a-comparison-to-the-rtog-0933-trial
#10
J Krayenbuehl, M Di Martino, M Guckenberger, N Andratschke
BACKGROUND: Whole-brain radiation therapy (WBRT) with hippocampus sparing (HS) has been investigated by the radiation oncology working group (RTOG) 0933 trial for patients with multiple brain metastases. They showed a decrease of adverse neurocognitive effects with HS WBRT compared to WBRT alone. With the development of automated treatment planning system (aTPS) in the last years, a standardization of the plan quality at a high level was achieved. The goal of this study was to evaluate the feasibility of using an aTPS for the treatment of HS WBRT and see if the RTOG 0933 dose constraints could be achieved and improved...
October 2, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28967281/radiation-fractionation-the-search-for-isoeffect-relationships-and-mechanisms
#11
John E Moulder, Colin Seymour
PURPOSE: Review the historical basis for the use of fractionated radiation in radiation oncology. CONCLUSION: The history of dose fractionation in radiation oncology is long and tortuous, and the radiobiologist's understanding of why fractionation worked came decades after radiation oncologists had adopted multi-week daily-dose fractionation as 'standard'. Central to the history is the search for 'isoeffective' formulas that would allow different radiation schedules to be compared...
October 2, 2017: International Journal of Radiation Biology
https://www.readbyqxmd.com/read/28964588/precision-oncology-and-genomically-guided-radiation-therapy-a-report-from-the-american-society-for-radiation-oncology-american-association-of-physicists-in-medicine-national-cancer-institute-precision-medicine-conference
#12
William A Hall, Carmen Bergom, Reid F Thompson, Andrew M Baschnagel, Srinivasan Vijayakumar, Henning Willers, X Allen Li, Christopher J Schultz, George D Wilson, Catharine M L West, Jacek Capala, C Norman Coleman, Javier F Torres-Roca, Joanne Weidhaas, Felix Y Feng
PURPOSE: To summarize important talking points from a 2016 symposium focusing on real-world challenges to advancing precision medicine in radiation oncology, and to help radiation oncologists navigate the practical challenges of precision, radiation oncology. METHODS AND MATERIALS: The American Society for Radiation Oncology, American Association of Physicists in Medicine, and National Cancer Institute cosponsored a meeting on precision medicine in radiation oncology...
June 9, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28951003/bladder-sparing-radiotherapy-for-muscle-invasive-bladder-cancer-a-qualitative-study-to-identify-barriers-and-enablers
#13
M Walker, R C Doiron, S D French, D Feldman-Stewart, D R Siemens, W J Mackillop, C M Booth
AIMS: Bladder-sparing radiotherapy for muscle-invasive bladder cancer (MIBC) may be underutilised in North America. To understand factors driving practice we used the Theoretical Domains Framework (TDF) to identify barriers and enablers of bladder-sparing radiotherapy utilisation. MATERIALS AND METHODS: A convenience sample of Canadian urologists, medical oncologists and radiation oncologists participated in individual semi-structured 1 h interviews. An interview guide was developed using the TDF to assess barriers and enablers of bladder-sparing radiotherapy use...
September 23, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28944980/failure-mode-and-effects-analysis-a-community-practice-perspective
#14
Bradley W Schuller, Angi Burns, Elizabeth A Ceilley, Alan King, Joan LeTourneau, Alexander Markovic, Lynda Sterkel, Brigid Taplin, Jennifer Wanner, Jeffrey M Albert
PURPOSE: To report our early experiences with failure mode and effects analysis (FMEA) in a community practice setting. METHODS: The FMEA facilitator received extensive training at the AAPM Summer School. Early efforts focused on department education and emphasized the need for process evaluation in the context of high profile radiation therapy accidents. A multidisciplinary team was assembled with representation from each of the major department disciplines. Stereotactic radiosurgery (SRS) was identified as the most appropriate treatment technique for the first FMEA evaluation, as it is largely self-contained and has the potential to produce high impact failure modes...
September 25, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28941581/use-of-frailty-to-predict-survival-in-elderly-patients-with-early-stage-non-small-cell-lung-cancer-treated-with-stereotactic-body-radiation-therapy
#15
Idalid Franco, Yu-Hui Chen, Fallon Chipidza, Vishesh Agrawal, John Romano, Elizabeth Baldini, Aileen Chen, Yolonda Colson, Ying Hou, David Kozono, Jon Wee, Raymond Mak
OBJECTIVES: Frailty has been shown to increase morbidity and mortality independent of age, but studies are lacking in radiation oncology. This study evaluates a modified frailty index (mFI) in predicting overall survival (OS) and non-cancer death for Stage I/II [N0M0] Non-Small-Cell Lung Cancer (NSCLC) patients treated with Stereotactic Body Radiation Therapy (SBRT). MATERIALS AND METHODS: Medical records for all patients with Stage I/II NSCLC treated at our institution with SBRT from 2009 to 2014 were reviewed...
September 20, 2017: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/28939574/publication-of-interventional-phase-3-and-4-clinical-trials-in-radiation-oncology-an-observational-study
#16
Jaime Pérez-Alija, Pedro Gallego, Isabel Linares, Eva Ambroa, Agustí Pedro
OBJECTIVES: Clinical trials produce the best data available for decision-making in modern evidence-based medicine. We aimed to determine the rate of non-publication of interventional phase 3 and 4 clinical trials involving patients with cancer undergoing radiotherapy. SETTING: The ClinicalTrials.gov database was searched for interventional phase 3 and 4 trials in radiotherapy with a primary completion date before 1 January 2013. We determined how many of these registry entries have not published the compulsory deposition of their results in the database and performed a systematic search for published studies in peer-reviewed journals...
September 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28927756/recent-time-trends-and-predictors-of-heart-dose-from-breast-radiation-therapy-in-a-large-quality-consortium-of-radiation-oncology-practices
#17
Lori J Pierce, Mary Feng, Kent A Griffith, Reshma Jagsi, Thomas Boike, Daniel Dryden, Gregory S Gustafson, Lisa Benedetti, Martha M Matuszak, Teamour S Nurushev, Joe Haywood, Jeffrey D Radawski, Corey Speers, Eleanor M Walker, James A Hayman, Jean M Moran
PURPOSE: Limited data exist regarding the range of heart doses received in routine practice with radiation therapy (RT) for breast cancer in the United States today and the potential effect of the continual assessment of the cardiac dose on practice patterns. METHODS AND MATERIALS: From 2012 to 2015, 4688 patients with breast cancer treated with whole breast RT at 20 sites participating in a state-wide consortium were enrolled into a registry. The importance of limiting the cardiac dose has been emphasized in the consortium since 2012, and the mean heart dose (MHD) has been reported by each institution since 2014...
July 22, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28927550/assessing-dose-variance-from-immobilization-devices-in-vmat-head-and-neck-treatment-planning-a-retrospective-case-study-analysis
#18
Alyssa Olson, Kristine Phillips, Tamara Eng, Nishele Lenards, Ashley Hunzeker, Daniel Lewis, Douglas Baumann
Immobilization devices serve several purposes in radiation oncology including improved positional reproducibility and decreased patient movement. If immobilization device beam attenuation is unaccounted for in the treatment planning process, planning target volume (PTV) coverage can be compromised. A retrospective case study was performed to evaluate beam attenuation from head and neck (HN) immobilization devices in volumetric-modulated arc therapy using the Eclipse treatment planning system and the Anisotropic Analytical Algorithm...
September 15, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28919249/dosimetric-predictors-for-acute-esophagitis-during-radiation-therapy-for-lung-cancer-results-of-a-large-statewide-observational-study
#19
Peter Paximadis, Matthew Schipper, Martha Matuszak, Mary Feng, Shruti Jolly, Thomas Boike, Inga Grills, Larry Kestin, Benjamin Movsas, Kent Griffith, Gregory Gustafson, Jean Moran, Teamour Nurushev, Jeffrey Radawski, Lori Pierce, James Hayman
PURPOSE: The purpose of this study is to identify dosimetric variables that best predict for acute esophagitis in patients treated for locally advanced non-small cell lung cancer in a prospectively accrued statewide consortium. METHODS AND MATERIALS: Patients receiving definitive radiation therapy for stage II-III non-small cell lung cancer within the Michigan Radiation Oncology Quality Consortium were included in the analysis. Dose-volume histogram data were analyzed to determine absolute volumes (cc) receiving doses from 10 to 60 Gy (V10, V20, V30, V40, V50, and V60), as well as maximum dose to 2 cc (D2cc), mean dose (MD), and generalized equivalent uniform dose (gEUD)...
July 19, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28917257/exploiting-molecular-genomics-in-precision-radiation-oncology-a-marriage-of-biological-and-physical-precision
#20
Janice S H Tan, Xiaotian Lin, Kevin L M Chua, Paula Y Lam, Khee-Chee Soo, Melvin L K Chua
Achieving local tumour control is paramount for cure in head and neck and prostate cancers. With the transition to precision radiotherapy (RT) techniques, survival rates have improved in the majority of these cancers, but a substantial proportion of 30-40% still relapse following primary treatment. Recent large-scale molecular profiling studies have revealed unique biological events that could explain for tumour aggression and resistance to therapies, redefining the molecular taxonomy of head and neck and prostate cancers...
September 2017: Chinese Clinical Oncology
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