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Radiation-oncology

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https://www.readbyqxmd.com/read/29923514/whole-body-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-18-f-fdg-pet-ct-for-staging-locally-advanced-breast-cancer-a-prospective-study-from-a-tertiary-cancer-centre-in-south-india
#1
Sivanath Reddy Gajjala, Narendra Hulikal, Silpa Kadiyala, Radhika Kottu, Tekchand Kalawat
Background & objectives: Locally advanced breast cancer (LABC) is associated with substantial risk of occult metastases. The patients with LABC have high rate of systemic relapse, suggesting inadequacy of the current conventional staging in detecting the occult metastatic spread. 18 F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET/CT) is a new modality in the staging of breast cancer patients. Hence, this study was conducted to evaluate the role of 18 F-FDG PET/CT in initial staging of LABC and to compare it with conventional methods...
March 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29916429/hyperbaric-oxygen-with-cord-blood-transplants-filling-the-donor-gap
#2
Vineet Govinda Gupta, Sameer Bakhshi
Aljitawi OS, Paul S, Ganguly A, Lin TL, Ganguly S, Vielhauer G, Capitano ML, Cantilena A, Lipe B, Mahnken JD, Wise A, Berry A, Singh AK, Shune L, Lominska C, Abhyankar S, Allin D, Laughlin M, McGuirk JP, Broxmeyer HE. (Division of Hematologic Malignancies and Cellular Therapy; Hematology and Transplantation Translational Research Laboratory ; Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas; Division of Hematology/Oncology and Bone Marrow Transplantation Program, University of Rochester Medical Center, Rochester, New York; Department of Urology, University of Kansas Medical Center, Kansas City, Kansas; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana; Cardiovascular Research Institute, Department of Biostatistics, Department of Radiation Oncology, Department of Emergency Medicine, University of Kansas Medical Center, Kansas City, Kansas; Cleveland Cord Blood Center, Cleveland, Ohio; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA...
September 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/29913252/quantitative-imaging-for-radiation-oncology
#3
Uulke A van der Heide, Daniela Thorwarth
No abstract text is available yet for this article.
June 15, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29909895/magnitude-of-benefit-for-adjuvant-radiotherapy-following-minimally-invasive-surgery-in-intermediate-to-high-risk-hpv-positive-oropharyngeal-squamous-cell-carcinoma
#4
Dario Pasalic, Ryan K Funk, Joaquín J García, Daniel L Price, Katharine A Price, William S Harmsen, Samir H Patel, Geoffrey D Young, Robert L Foote, Eric J Moore, Daniel J Ma
OBJECTIVE: To determine the outcomes and toxicities of minimally-invasive surgery with adjuvant intensity-modulated radiotherapy +/- chemotherapy (AT) compared to definitive surgical therapy (ST) in a contemporary cohort of HPV-positive oropharyngeal squamous cell carcinoma (OPSCC). METHODS: From 2005 to 2013, a consecutive cohort of 190 HPV-positive OPSCC patients was retrospectively reviewed from multi-institutional databases maintained by the Departments of Otorhinolaryngology and Radiation Oncology...
July 2018: Oral Oncology
https://www.readbyqxmd.com/read/29908787/objective-evaluation-of-a-didactic-curriculum-for-the-radiation-oncology-medical-student-clerkship
#5
Daniel W Golden, Gregory E Kauffmann, Ryan P McKillip, Jeanne M Farnan, Yoon Soo Park, Alan Schwartz
PURPOSE: A structured didactic radiation oncology clerkship curriculum for medical students is in use at multiple academic medical centers. Objective evidence supporting this educational approach over the traditional clerkship model is lacking. This study evaluated the curriculum efficacy using an objective knowledge assessment. METHODS AND MATERIALS: Medical students received the Radiation Oncology Education Collaborative Study Group (ROECSG) curriculum consisting of 3 lectures (Overview of Radiation Oncology, Radiation Biology/Physics, and Practical Aspects of Simulation/Radiation Emergencies) and a radiation oncology treatment-planning workshop...
April 26, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29907512/thoughts-on-the-american-board-of-radiology-examinations-and-the-resident-experience-in-radiation-oncology
#6
EDITORIAL
Paul E Wallner, Lisa A Kachnic, Anthony M Gerdeman
No abstract text is available yet for this article.
April 10, 2018: Practical Radiation Oncology
https://www.readbyqxmd.com/read/29907508/using-a-real-time-location-system-to-measure-patient-flow-in-a-radiation-oncology-outpatient-clinic
#7
Kevin Conley, Chester Chambers, Shereef Elnahal, Amanda Choflet, Kayode Williams, Theodore DeWeese, Joseph Herman, Maqbool Dada
PURPOSE: Common performance metrics for outpatient clinics define the time between patient arrival and entry into an examination room as "waiting time." Time spent in the room is considered processing time. This characterization systematically ignores time spent in the examination room waiting for service. If these definitions are used, performance will consistently understate total waiting times and overstate processing times. Correcting such errors will provide a better understanding of system behavior...
May 5, 2018: Practical Radiation Oncology
https://www.readbyqxmd.com/read/29907507/nrg-oncology-medical-physicists-manpower-survey-quantifying-support-demands-for-multi-institutional-clinical-trials
#8
James I Monroe, Karan Boparai, Ying Xiao, David Followill, James M Galvin, Eric E Klein, Daniel A Low, Jean M Moran, Haoyu Zhong, Jason W Sohn
PURPOSE: A survey was created by NRG to assess a medical physicists' percent full time equivalent (FTE) contribution to multi-institutional clinical trials. A 2012 American Society for Radiation Oncology report, "Safety Is No Accident," quantified medical physics staffing contributions in FTE factors for clinical departments. No quantification of FTE effort associated with clinical trials was included. METHODS: To address this lack of information, the NRG Medical Physics Subcommittee decided to obtain manpower data from the medical physics community to quantify the amount of time medical physicists spent supporting clinical trials...
February 4, 2018: Practical Radiation Oncology
https://www.readbyqxmd.com/read/29907503/real-time-management-of-incident-learning-reports-in-a-radiation-oncology-department
#9
REVIEW
Jean L Wright, Arti Parekh, Byung-Han Rhieu, Valentina Opris, Annette Souranis, Amanda Choflet, Akila N Viswanathan, Theodore L DeWeese, Todd McNutt, Stephanie A Terezakis
PURPOSE: The optimal approach to managing incident learning system (ILS) reports remains unclear. Here, we describe our experience with prospective coding of events reported to the ILS with comparisons of risk scores on the basis of event type and process map location. METHODS AND MATERIALS: Reported events were coded by type, origin, and method of discovery. Events were given a risk priority number (RPN) and near-miss risk index (NMRI) score. We compared workflow versus near-miss events with respect to origin and detection in the process map and by risk scores...
May 8, 2018: Practical Radiation Oncology
https://www.readbyqxmd.com/read/29907490/multi-institutional-study-of-carbon-ion-radiotherapy-for-locally-advanced-pancreatic-cancer-japan-carbon-ion-radiation-oncology-study-group-j-cros-study-1403-pancreas
#10
Shohei Kawashiro, Shigeru Yamada, Masahiko Okamoto, Tatsuya Ohno, Takashi Nakano, Makoto Shinoto, Yoshiyuki Shioyama, Kenji Nemoto, Yuka Isozaki, Hiroshi Tsuji, Tadashi Kamada
PURPOSE: The aim of this multi-institutional study was to evaluate the efficacy and safety of carbon-ion radiotherapy (C-ion RT) for locally advanced pancreatic cancer (LAPC). METHODS AND MATERIALS: Patients with LAPC treated with C-ion RT from April 2012 to December 2014 at 3 institutions were retrospectively analyzed. Patients with pathologically-confirmed invasive ductal adenocarcinoma of the pancreas were eligible. The prescribed dose was 52.8 Gy (relative biological effectiveness weighted absorbed dose; RBE) or 55...
May 1, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29907338/artificial-intelligence-in-radiation-oncology-a-specialty-wide-disruptive-transformation
#11
REVIEW
Reid F Thompson, Gilmer Valdes, Clifton D Fuller, Colin M Carpenter, Olivier Morin, Sanjay Aneja, William D Lindsay, Hugo J W L Aerts, Barbara Agrimson, Curtiland Deville, Seth A Rosenthal, James B Yu, Charles R Thomas
Artificial intelligence (AI) is emerging as a technology with the power to transform established industries, and with applications from automated manufacturing to advertising and facial recognition to fully autonomous transportation. Advances in each of these domains have led some to call AI the "fourth" industrial revolution [1]. In healthcare, AI is emerging as both a productive and disruptive force across many disciplines. This is perhaps most evident in Diagnostic Radiology and Pathology, specialties largely built around the processing and complex interpretation of medical images, where the role of AI is increasingly seen as both a boon and a threat...
June 12, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29904736/lung-cancer-specialists-opinions-on-treatment-for-stage-i-non-small-cell-lung-cancer-a-multidisciplinary-survey
#12
Austin Lammers, Timur Mitin, Drew Moghanaki, Charles R Thomas, Robert Timmerman, Sara E Golden, Sujata Thakurta, Rafal Dziadziuszko, Christopher G Slatore
Purpose: The current standard of care for surgically eligible stage I non-small cell lung cancer (NSCLC) is surgical resection, but emerging data suggest that stereotactic body radiation therapy (SBRT) is potentially as effective as surgery. However, specialist views of the current evidence about SBRT and how they would incorporate a randomized controlled trial (RCT) into practice is unclear. We sought to understand specialist opinions about evidence regarding treatment of stage I NSCLC and how this translates into practice and clinical trial implementation...
April 2018: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29904616/artificial-intelligence-in-medicine-and-radiation-oncology
#13
REVIEW
Vincent Weidlich, Georg A Weidlich
Artifical Intelligence (AI) was reviewed with a focus on its potential applicability to radiation oncology. The improvement of process efficiencies and the prevention of errors were found to be the most significant contributions of AI to radiation oncology. It was found that the prevention of errors is most effective when data transfer processes were automated and operational decisions were based on logical or learned evaluations by the system. It was concluded that AI could greatly improve the efficiency and accuracy of radiation oncology operations...
April 13, 2018: Curēus
https://www.readbyqxmd.com/read/29903505/randomised-phase-ii-feasibility-trial-of-image-guided-external-beam-radiotherapy-with-or-without-high-dose-rate-brachytherapy-boost-in-men-with-intermediate-risk-prostate-cancer-cctg-pr15-nct01982786
#14
E Vigneault, G Morton, W R Parulekar, T M Niazi, C W Springer, M Barkati, P Chung, W Koll, A Kamran, M Monreal, K Ding, A Loblaw
AIMS: We conducted a multicentre feasibility study to assess the ability to randomise patients between image-guided radiotherapy (IGRT) and IGRT + high dose rate (HDR) brachytherapy boost and to adhere to appropriate radiation quality assurance standards. MATERIALS AND METHODS: The primary end point was to determine the ability to randomise 60 patients over an 18 month period. Arm 1 (IGRT) patients received 78 Gy in 39 fractions or 60 Gy in 20 fractions (physician's preference), whereas arm 2 (IGRT + HDR) received 37...
June 11, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29900611/not-asking-cancer-patients-about-their-preferences-does-make-a-difference-a-cross-sectional-study-examining-cancer-patients-preferred-and-perceived-role-in-decision-making-regarding-their-last-important-cancer-treatment
#15
Anne Herrmann, Alix Hall, Rob Sanson-Fisher, Nicholas Zdenkowski, Rochelle Watson, Heidi Turon
We examined whether not having been asked by their clinicians about how involved cancer patients would like to be in their treatment decisions is related to discordance between patients' preferred and perceived involvement in treatment decision-making. This was a cross-sectional survey of adult cancer patients recruited from five medical and radiation oncology outpatient clinics in Australia. Discordance of patients' preferred and perceived decision-making roles was assessed via an adapted version of the Control Preferences Scale...
June 14, 2018: European Journal of Cancer Care
https://www.readbyqxmd.com/read/29893309/breast-specific-functional-and-symptom-analysis-in-female-breast-cancer-survivors
#16
Shaqul Qamar Wani, Talib Khan, Saiful Yamin Wani, Mohammad Ashraf Teli, Nazir Ahmad Khan, Liza Rafiq Mir, Mohammad Maqbool Lone, Fir Afroz
Context: The disease and surgery of the breast not only evoke a fear of mutilation and loss of feminity but is also responsible for psychosocial, behavioral, and sexual problems. Aim: To analyze prospectively the time trends in "breast specific functional and symptom scale scores in female breast cancer survivors." Settings and Design: The prospective study was conducted in the Department of Radiation Oncology at Tertiary Referral Hospital...
April 2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29893281/mentorship-experiences-of-early-career-academic-radiation-oncologists-in-north-america
#17
Nafisha Lalani, Kent A Griffith, Rochelle D Jones, Daniel E Spratt, Jennifer Croke, Reshma Jagsi
PURPOSE: Given concerns about attrition and career outcomes of academic radiation oncologists, we sought to gather empirical evidence regarding mentorship experiences. METHODS AND MATERIALS: We surveyed academic radiation oncologists in the United States and Canada who were within 5 years of board certification, using a pretested questionnaire that included 14 questions evaluating the following aspects of mentorship: relationship development, peer mentorship, satisfaction with mentorship, sponsorship, relationship nature, informal interactions, mentoring roles, presence of a primary mentor, and primary mentor characteristics...
July 1, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29893272/total-body-irradiation-guidelines-from-the-international-lymphoma-radiation-oncology-group-ilrog
#18
REVIEW
Jeffrey Y C Wong, Andrea Riccardo Filippi, Bouthaina Shbib Dabaja, Joachim Yahalom, Lena Specht
Total body irradiation (TBI) remains an effective myeloablative treatment in regimens used for preparation and conditioning before allogeneic stem cell transplantation for leukemia. The regimens used vary across institutions in terms of dose, dose rate, fractionation, and technique. The objective of this document is to provide comprehensive guidelines for the current practice of delivering total body irradiation.
July 1, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29891263/treatment-design-and-rationale-for-a-randomized-trial-of-prophylactic-cranial-irradiation-with-or-without-hippocampal-avoidance-for-sclc-premer-trial-on-behalf-of-the-oncologic-group-for-the-study-of-lung-cancer-spanish-radiation-oncology-group-radiation-oncology
#19
Nuria Rodríguez de Dios, Felipe Couñago, José Luis López, Patricia Calvo, Mauricio Murcia, Mikel Rico, Carmen Vallejo, Javier Luna, Itziar Trueba, Cristina Cigarral, Nuria Farre, Rosa Maria Manero, Xavier Durán, Pilar Samper
BACKGROUND: Prophylactic cranial irradiation (PCI) is part of the usual treatment in most patients with small-cell lung cancer (SCLC) and response after treatment of the primary tumor. Clinical evidence suggests that radiation dose received by the hippocampus during whole brain radiotherapy might play a role in radiation-induced neurocognitive decline. PATIENTS AND METHODS: This study is a multicenter phase III trial (NCT02397733) randomizing SCLC patients after informed consent, to receive standard PCI treatment or PCI with hippocampus avoidance (PCI-HA) by using intensity modulated radiation therapy or volumetric modulated arc therapy...
May 10, 2018: Clinical Lung Cancer
https://www.readbyqxmd.com/read/29889468/long-term-follow-up-results-of-concomitant-chemoradiotherapy-followed-by-adjuvant-temozolomide-therapy-for-glioblastoma-multiforme-patients-the-importance-of-mri-information-in-survival-single-center-experience
#20
Gábor Lukács, Zoltán Tóth, Dávid Sipos, Melinda Csima, Janaki Hadjiev, Gábor Bajzik, Zsolt Cselik, Dávid Semjén, Imre Repa, Árpád Kovács
Background and purpose: Glioblastoma multiforme (GBM) is the most common malignant primary anomaly of central nervous system. The GBM infiltrates the nearly sturctures from the initial tumor and its metastatic attribution is well known. The aim of our single-centered retrospective study was to introduce the importance of postoperative medical imaging confirmation of total tumor resection for patient with GBM combined concomitant and adjuvant chemoradiotherapy on a 10 year long patient follow up...
March 30, 2018: Ideggyógyászati Szemle
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