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Radiation-oncology

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https://www.readbyqxmd.com/read/28726045/the-use-of-psychological-supportive-care-services-and-psychotropic-drugs-in-patients-with-early-stage-breast-cancer-a-comparison-between-two-institutions-on-two-continents
#1
Orit Kaidar-Person, Icro Meattini, Allison M Deal, Giulio Francolini, Giulio Carta, Lauren Terzo, Jayne Camporeale, Hyman Muss, Lawrence B Marks, Lorenzo Livi, Deborah K Mayer, Timothy M Zagar
The aim of this study was to evaluate the mental health consumption among patients with early-stage breast cancer in two radiation oncology departments in two countries (USA and Italy). Data were extracted from the medical records of consecutive patients treated between 2014 and 2015 in two centers. Extracted data included patient's demographics, treatment, referral to psychological supportive care programs, and prescribed psychotropic drugs. Data from the two centers were compared using Student's t, Wilcoxon, Fisher's exact, and Jonckheere-Terpstra tests...
August 2017: Medical Oncology
https://www.readbyqxmd.com/read/28721910/defining-and-shattering-the-glass-ceiling-in-radiation-oncology
#2
Miriam A Knoll
No abstract text is available yet for this article.
August 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28721904/treatment-planning-system-calculation-errors-are-present-in-most-imaging-and-radiation-oncology-core-houston-phantom-failures
#3
James R Kerns, Francesco Stingo, David S Followill, Rebecca M Howell, Adam Melancon, Stephen F Kry
PURPOSE: The anthropomorphic phantom program at the Houston branch of the Imaging and Radiation Oncology Core (IROC-Houston) is an end-to-end test that can be used to determine whether an institution can accurately model, calculate, and deliver an intensity modulated radiation therapy dose distribution. Currently, institutions that do not meet IROC-Houston's criteria have no specific information with which to identify and correct problems. In the present study, an independent recalculation system was developed to identify treatment planning system (TPS) calculation errors...
August 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28721899/gaps-in-radiation-therapy-awareness-results-from-an-educational-multi-institutional-survey-of-us-internal-medicine-residents
#4
Narek Shaverdian, Sun Mi Yoo, Ryan Cook, Eric M Chang, Naomi Jiang, Ye Yuan, Kiri Sandler, Michael Steinberg, Percy Lee
PURPOSE: Internists and primary care providers play a growing role in cancer care. We therefore evaluated the awareness of radiation therapy in general and specifically the clinical utility of stereotactic body radiation therapy (SBRT) for early-stage non-small cell lung cancer (NSCLC) among current US internal medicine residents. METHODS AND MATERIALS: A web-based institutional review board-approved multi-institutional survey was distributed to US internal medicine residency programs...
August 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28717901/performance-assessment-of-a-programmable-five-degrees-of-freedom-motion-platform-for-quality-assurance-of-motion-management-techniques-in-radiotherapy
#5
Chen-Yu Huang, Paul Keall, Adam Rice, Emma Colvill, Jin Aun Ng, Jeremy T Booth
Inter-fraction and intra-fraction motion management methods are increasingly applied clinically and require the development of advanced motion platforms to facilitate testing and quality assurance program development. The aim of this study was to assess the performance of a 5 degrees-of-freedom (DoF) programmable motion platform HexaMotion (ScandiDos, Uppsala, Sweden) towards clinically observed tumor motion range, velocity, acceleration and the accuracy requirements of SABR prescribed in AAPM Task Group 142...
July 17, 2017: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/28717717/management-and-care-of-women-with-invasive-cervical-cancer-american-society-of-clinical-oncology-resource-stratified-clinical-practice-guideline
#6
Linus T Chuang, Sarah Temin, Rolando Camacho, Alfonso Dueñas-Gonzalez, Sarah Feldman, Murat Gultekin, Vandana Gupta, Susan Horton, Graciela Jacob, Elizabeth A Kidd, Kennedy Lishimpi, Carolyn Nakisige, Joo-Hyun Nam, Hextan Yuen Sheung Ngan, William Small, Gillian Thomas, Jonathan S Berek
PURPOSE: To provide evidence-based, resource-stratified global recommendations to clinicians and policymakers on the management and palliative care of women diagnosed with invasive cervical cancer. METHODS: ASCO convened a multidisciplinary, multinational panel of cancer control, medical and radiation oncology, health economic, obstetric and gynecologic, and palliative care experts to produce recommendations reflecting resource-tiered settings. A systematic review of literature from 1966 to 2015 failed to yield sufficiently strong quality evidence to support basic- and limited-resource setting recommendations; a formal consensus-based process was used to develop recommendations...
October 2016: Journal of Global Oncology
https://www.readbyqxmd.com/read/28713771/integrating-hyperthermia-into-modern-radiation-oncology-what-evidence-is-necessary
#7
REVIEW
Jan C Peeken, Peter Vaupel, Stephanie E Combs
Hyperthermia (HT) is one of the hot topics that have been discussed over decades. However, it never made its way into primetime. The basic biological rationale of heat to enhance the effect of radiation, chemotherapeutic agents, and immunotherapy is evident. Preclinical work has confirmed this effect. HT may trigger changes in perfusion and oxygenation as well as inhibition of DNA repair mechanisms. Moreover, there is evidence for immune stimulation and the induction of systemic immune responses. Despite the increasing number of solid clinical studies, only few centers have included this adjuvant treatment into their repertoire...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28712282/deformable-image-registration-in-radiation-therapy
#8
REVIEW
Seungjong Oh, Siyong Kim
The number of imaging data sets has significantly increased during radiation treatment after introducing a diverse range of advanced techniques into the field of radiation oncology. As a consequence, there have been many studies proposing meaningful applications of imaging data set use. These applications commonly require a method to align the data sets at a reference. Deformable image registration (DIR) is a process which satisfies this requirement by locally registering image data sets into a reference image set...
June 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/28712101/molecular-profiling-in-the-practice-of-radiation-oncology
#9
Brian Marples, Alan Pollack
No abstract text is available yet for this article.
July 15, 2017: Oncology (Williston Park, NY)
https://www.readbyqxmd.com/read/28712100/the-role-of-genomic-techniques-in-predicting-response-to-radiation-therapy
#10
REVIEW
Noelle L Williams, Tu Dan, Nicholas G Zaorsky, Shivank Garg, Robert B Den
The understanding of the relationship between genetic variation and an individual patient's response to radiation therapy (RT) has gained significant ground over the past several years. Genetic markers have been identified that could ultimately serve as the foundation for predictive models in clinical practice, and that hold the potential to revolutionize the delivery of precision medicine in oncology. Single nucleotide polymorphisms, single genes, and/or gene signatures could ultimately serve as the basis for patient stratification in prospective clinical trials...
July 15, 2017: Oncology (Williston Park, NY)
https://www.readbyqxmd.com/read/28704643/multidisciplinary-training-of-cancer-specialists-in-europe
#11
Kim Benstead, Nazim Serdar Turhal, Niall O'Higgins, Lynda Wyld, Magdalena Czarnecka-Operacz, Harald Gollnick, Peter Naredi, Jesper Grau Eriksen
The best care for patients with cancer is most likely to be achieved when decisions about diagnosis, staging and treatment are made at multidisciplinary and multiprofessional meetings, preferably when all the professional expertise relevant to the patient's condition is gathered together. Questionnaires were sent to National Societies of Radiation Oncology and Medical Oncology concerning similarities and differences in training programs and multidisciplinary care in member states in Europe. Results indicated wide variation in training systems and practice...
July 10, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28697786/spinal-bone-metastases-in-colorectal-cancer-a-retrospective-analysis-of-stability-prognostic-factors-and-survival-after-palliative-radiotherapy
#12
Tilman Bostel, Robert Förster, Ingmar Schlampp, Tania Sprave, Thomas Bruckner, Nils Henrik Nicolay, Stefan Ezechiel Welte, Jürgen Debus, Harald Rief
BACKGROUND: This retrospective analysis aimed to analyse the stability of spinal bone metastases in colorectal cancer (CRC) patients following radiotherapy (RT) by use of a validated score and to assess prognostic factors for stability and survival. METHODS: Ninety-four patients with osteolytic spinal bone metastases from CRC were treated at the Department of Radiation Oncology at the University Hospital Heidelberg between 2000 and 2014. The stability of each affected vertebral body was assessed according to the validated Taneichi bone stability score on the basis of the treatment planning CT scan prior to RT and also based on the follow-up CT examinations at 3 and 6 months after RT...
July 11, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28695316/interobserver-variability-in-target-volume-delineation-of-hepatocellular-carcinoma-an-analysis-of-the-working-group-stereotactic-radiotherapy-of-the-german-society-for-radiation-oncology-degro
#13
E Gkika, S Tanadini-Lang, S Kirste, P A Holzner, H P Neeff, H C Rischke, T Reese, F Lohaus, M N Duma, K Dieckmann, R Semrau, M Stockinger, D Imhoff, N Kremers, M F Häfner, N Andratschke, U Nestle, A L Grosu, M Guckenberger, T B Brunner
BACKGROUND: Definition of gross tumor volume (GTV) in hepatocellular carcinoma (HCC) requires dedicated imaging in multiple contrast medium phases. The aim of this study was to evaluate the interobserver agreement (IOA) in gross tumor delineation of HCC in a multicenter panel. METHODS: The analysis was performed within the "Stereotactic Radiotherapy" working group of the German Society for Radiation Oncology (DEGRO). The GTVs of three anonymized HCC cases were delineated by 16 physicians from nine centers using multiphasic CT scans...
July 10, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28693933/-partially-matched-us-senior-diagnostic-radiology-applicants-scope-of-the-problem-and-implications-for-applicants-residency-training-programs-and-the-academic-diagnostic-radiology-community
#14
Keith D Herr, Sravanthi Reddy, Elizabeth A Krupinski, Mark E Mullins, Christopher Straus
RATIONALE AND OBJECTIVES: Anecdotal reports have recently surfaced of an increase in the number of US senior diagnostic radiology (DR)-bound residency applicants who did not secure a preliminary year position through the Main Resident Match (the Match) of the National Resident Matching Program (NRMP), so-called "partial matches." This study sought to determine the scope of this phenomenon and address potential causes and solutions. MATERIALS AND METHODS: Publicly available and proprietary data from the National Resident Matching Program were analyzed from 2005-2016 to determine the number of partially matched US senior applicants, selectivity of DR residency training, availability of preliminary year positions, number of unique preliminary year applicants, distribution of preliminary year matches by successfully matched applicants in relevant specialties (DR, anesthesiology, dermatology, neurology, physical medicine and rehabilitation, and radiation oncology), and percentage of categorical training programs participating in the Match...
June 5, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28690104/a-clinical-perspective-on-regional-nodal-irradiation-for-breast-cancer
#15
Amy C Moreno, Simona F Shaitelman, Thomas A Buchholz
The goal of regional treatments in breast cancer should be to eradicate any disease within lymph nodes, avoid regional recurrences, minimize the risk of distant metastases, and improve survival. In addition, regional treatments should focus on reducing potential morbidities and optimizing the long-term quality of life of breast cancer survivors. While data from recent surgical and radiation trials have helped clarify many issues regarding regional treatment, there still remains controversy as to the optimal approach for patients with "intermediate risk" disease...
July 6, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28688910/burden-of-palliative-care-issues-encountered-by-radiation-oncologists-caring-for-patients-with-advanced-cancer
#16
Gregory M Parker, Virginia T LeBaron, Monica Krishnan, Ron Y Shiloh, Alexander Spektor, Lauren Hertan, Tracy A Balboni
PURPOSE: Radiation oncologists frequently provide care for patients with advanced cancer who are in their last months or weeks of life. This study examined the previously not well-characterized types and frequencies of palliative care issues encountered in consultations for palliative radiation therapy (PRT). METHODS AND MATERIALS: This prospective, survey-based study assessed consecutive consults for PRT from May 19, 2014, to September 26, 2014 at 3 Boston-area community and academic, hospital-based centers...
May 25, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28688909/are-we-making-an-impact-with-incident-learning-systems-analysis-of-quality-improvement-interventions-using-total-body-irradiation-as-a-model-system
#17
Aileen Kim, Eric Ford, Matthew Spraker, Jing Zeng, Ralph Ermoian, Loucille Jordan, Gabrielle Kane, Matthew Nyflot
PURPOSE: Despite increasing interest in incident learning systems (ILS) to improve safety and quality in radiation oncology, little is known about interventions developed in response to safety data. We used total body irradiation (TBI) as a model system to study the effectiveness of interventions from our institutional ILS. METHODS AND MATERIALS: Near-miss event reports specific to TBI were identified from a departmental ILS from March 2012 to December 2015. The near-miss risk index was rated at multidisciplinary review from 0 (no potential harm) to 4 (critical potential harm)...
June 6, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28687979/-radio-oncomics-the-potential-of-radiomics-in-radiation-oncology
#18
Jan Caspar Peeken, Fridtjof Nüsslin, Stephanie E Combs
INTRODUCTION: Radiomics, a recently introduced concept, describes quantitative computerized algorithm-based feature extraction from imaging data including computer tomography (CT), magnetic resonance imaging (MRT), or positron-emission tomography (PET) images. For radiation oncology it offers the potential to significantly influence clinical decision-making and thus therapy planning and follow-up workflow. METHODS: After image acquisition, image preprocessing, and defining regions of interest by structure segmentation, algorithms are applied to calculate shape, intensity, texture, and multiscale filter features...
July 7, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28680278/current-practice-in-total-body-irradiation-results-of-a-canada-wide-survey
#19
R C N Studinski, D J Fraser, R S Samant, M S MacPherson
BACKGROUND: Total-body irradiation (tbi) is used to condition patients before bone marrow transplant. A variety of tbi treatment strategies have been described and implemented, but no consensus on best practice has been reached. We report on the results of a survey created to assess the current state of tbi delivery in Canada. RESULTS: A 19-question survey was distributed to 49 radiation oncology programs in Canada. Responses were received from 20 centres, including 12 centres that perform tbi...
June 2017: Current Oncology
https://www.readbyqxmd.com/read/28678889/modification-and-optimization-of-an-established-prognostic-score-after-re-irradiation-of-recurrent-glioma
#20
Kerstin A Kessel, Josefine Hesse, Christoph Straube, Claus Zimmer, Friederike Schmidt-Graf, Jürgen Schlegel, Bernhard Meyer, Stephanie E Combs
INTRODUCTION: For about 30 years, researchers developed prognostic scores and searched for prognostic factors to predict outcomes for cancer patients. The "Combs Prognostic Score" for re-irradiation in recurrent glioma was recently validated and results showed that the score is a significant (p < .001) and reliable predictor for patients undergoing re-irradiation (re-RT). We sought to enhance the score and generated a novel scoring approach, taking into account the information on resection of recurrent tumors, KPS, and tumor volume...
2017: PloS One
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