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https://www.readbyqxmd.com/read/29858979/multifarious-diagnostic-possibilities-of-the-s100-protein-family-predominantly-in-pediatrics-and-neonatology
#1
REVIEW
Anna Medkova, Josef Srovnal, Jarmila Potomkova, Jana Volejnikova, Vladimir Mihal
BACKGROUND: Numerous articles related to S100 proteins have been recently published. This review aims to introduce this large protein family and its importance in the diagnostics of many pathological conditions in children and adults. DATA SOURCES: Based on original publications found in database systems, we summarize the current knowledge about the S100 protein group and highlight the most important proteins with focus on pediatric use. RESULTS: The S100 family is composed of Ca2+  and Zn2+  binding proteins, which are present only in vertebrates...
June 1, 2018: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/29806474/-perioperative-use-of-levosimendan-in-cardiac-surgery-hungarian-recommendation
#2
László Szudi, László Székely, Erzsébet Sápi, Zsolt Prodán, Jenő Szolnoky, Ákos Csomós, Noémi Nyolczas, Erzsébet Paulovich, Endre Németh, István Hartyánszky, Endre Zima, Balázs Sax, Andrea Bertalan, László Hejjel, Gábor Bogáts, Barna Babik, Károly Gombocz, Tamás Szerafin, György Koszta, Andrea Molnár
Low output syndrome significantly increases morbidity and mortality of cardiac surgery and lengthens the durations of intensive care unit and hospital stays. Its treatment by catecholamines can lead to undesirable systemic and cardiac complications. Levosimendan is a calcium sensitiser and adenosine triphosphate (ATP)-sensitive potassium channel (IK,ATP ) opener agent. Due to these effects, it improves myocardium performance, does not influence adversely the balance between O2 supply and demand, and possesses cardioprotective and organ protective properties as well...
June 2018: Orvosi Hetilap
https://www.readbyqxmd.com/read/29806196/the-use-of-light-s-criteria-in-hospitalized-children-with-a-pleural-effusion-of-unknown-etiology
#3
Matthew D McGraw, Kyle Robison, Oren Kupfer, John T Brinton, Paul C Stillwell
OBJECTIVE: Pleural effusions are common in pediatrics. When the etiology of a pleural effusion remains unknown, adult literature recommends the use of Light's criteria to differentiate a transudate from an exudate. Pediatricians may rely on adult literature for the diagnostic management of pleural effusions as Light's criteria has not been validated in children. The purpose of this study was to review the use of Light's criteria in hospitalized children with a pleural effusion of unknown etiology...
May 27, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29794950/adolescent-seizure-in-the-emergency-department-due-to-concomitant-brugada-syndrome
#4
Beau Baum, Oscar Ingaramo, David Chao
Brugada syndrome is an increasingly discussed entity in the emergency medicine and cardiology literature. However, there are few cases reported in the pediatric population. Seizure is a presentation common to pediatric emergency departments. This case report describes the clinical course, workup, and differential diagnosis of a 15-year-old male adolescent with first-time seizure and Brugada pattern on electrocardiogram. A brief review of the literature follows the case presentation.
May 23, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29761681/milestones-in-the-development-of-fetal-cardiac-interventions
#5
REVIEW
Edward G Abinader
Cardiac patients of all ages were managed in the past by internists who specialized in cardiology. During the past 50 years, the medical field has witnessed great strides in the management of congenital heart disease, and thus pediatric cardiology has become a subspecialty in many countries. This review article focuses on the advances in fetal cardiac interventions (FCI) since its inception by our group in 1975. Three major modes of FCI have evolved during the past 42 years: pharmacologic, closed FCI, and open FCI...
May 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29761136/yield-of-echocardiogram-and-predictors-of-positive-yield-in-pediatric-patients-a-study-in-an-urban-community-based-outpatient-pediatric-cardiology-clinic
#6
Ramya Deepthi Billa, Susan Szpunar, Lida Zeinali, Premchand Anne
The yield of outpatient echocardiograms varies based on the indication for the echocardiogram and the age of the patient. The purpose of this study was to determine the cumulative yield of outpatient echocardiograms by age group and reason for the test. A secondary aim was to determine the predictors of a positive echocardiogram in an outpatient cardiology clinic at a large community teaching hospital. We retrospectively reviewed the charts of 891 patients who had a first-time echocardiogram between 2011 and 2015...
2018: Global Pediatric Health
https://www.readbyqxmd.com/read/29744656/pediatric-pulmonary-artery-rehabilitation-a-review-of-our-experience-and-a-novel-approach-using-bronchial-blockers
#7
Peter D Winch, Dmitry Tumin, Jeffrey Moore, Samantha J Vizzini, Darren P Berman, Aymen N Naguib
Recent advances in the field of pediatric interventional cardiology have resulted in therapies for patients in need of augmented pulmonary artery (PA) flow. Catheter-based PA rehabilitation can be performed safely but not without the potential risk of pulmonary hemorrhage. When severe, this bleeding has the ability to contaminate the bronchi and trachea, and possibly occlude the endotracheal tube. This can result in a critical inability to ventilate and oxygenate these patients. Herein, we review our institutional experience with pulmonary hemorrhage associated with these procedures and the feasibility of predicting this outcome...
May 9, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29726431/telemedicine-in-diagnosis-treatment-and-management-of-diseases-in-children
#8
Abbas Sheikhtaheri, Farzaneh Kermani
The purpose of this study was to review different telemedicine services in diagnosis, treatment and management of various children diseases and providing an overview of systematic reviews conducted in this regard. We searched English articles published in peer-reviewed journals between 2000 to 2016. We found that tele-pediatric services have been reported in various areas such as cardiology, burn, diabetes, obesity, emergency medicine, speech and hearing loss, Ear, Nose and Throat, psychology and psychiatry, radiology, oncology, home healthcare, asthma, genetics and dentistry...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29685887/cardiopulmonary-resuscitation-in-infants-and-children-with-cardiac-disease-a-scientific-statement-from-the-american-heart-association
#9
REVIEW
Bradley S Marino, Sarah Tabbutt, Graeme MacLaren, Mary Fran Hazinski, Ian Adatia, Dianne L Atkins, Paul A Checchia, Allan DeCaen, Ericka L Fink, George M Hoffman, John L Jefferies, Monica Kleinman, Catherine D Krawczeski, Daniel J Licht, Duncan Macrae, Chitra Ravishankar, Ricardo A Samson, Ravi R Thiagarajan, Rune Toms, James Tweddell, Peter C Laussen
Cardiac arrest occurs at a higher rate in children with heart disease than in healthy children. Pediatric basic life support and advanced life support guidelines focus on delivering high-quality resuscitation in children with normal hearts. The complexity and variability in pediatric heart disease pose unique challenges during resuscitation. A writing group appointed by the American Heart Association reviewed the literature addressing resuscitation in children with heart disease. MEDLINE and Google Scholar databases were searched from 1966 to 2015, cross-referencing pediatric heart disease with pertinent resuscitation search terms...
May 29, 2018: Circulation
https://www.readbyqxmd.com/read/29656718/the-pediatric-heart-network-scholar-award-programme-a-unique-mentored-award-embedded-within-a-multicentre-network
#10
L LuAnn Minich, Victoria L Pemberton, Lara S Shekerdemian, Morgan M Millar, Jane W Newburger, Andrew C Glatz, Eric M Graham, Richard J Czosek, Sara K Pasquali, Mike Seed, William L Border
BACKGROUND: The Pediatric Heart Network designed a career development award to train the next generation of clinician scientists in paediatric-cardiology-related research, a historically underfunded area. We sought to identify the strengths/weaknesses of the programme and describe the scholars' academic achievements and the network's return on investment. METHODS: Survey questions designed to evaluate the programme were sent to applicants - 13 funded and 19 unfunded applicants - and 20 mentors and/or principal investigators...
June 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29623173/spontaneous-closure-of-a-secundum-atrial-septal-defect
#11
Stephen Y Wang, Terrence D Welch, Aryé Elfenbein, Aaron V Kaplan
Spontaneous closure of an atrial septal defect (ASD) is well described in pediatric cardiology but may be less familiar to adult internists and cardiologists. We report a moderately sized 6-mm ASD that closed spontaneously without intervention. A literature review found that a smaller defect size and an early age of diagnosis are the most important predictors of closure. Possible mechanisms of a spontaneous ASD closure include adaptive endothelial migration, limited myocardial proliferation, and fibroblast migration with extracellular matrix deposition...
January 2018: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/29561945/positron-emission-tomography-magnetic-resonance-imaging-pet-mri-an-update-and-initial-experience-at-hc-fmusp
#12
REVIEW
Marcelo A Queiroz, Felipe de Galiza Barbosa, Carlos Alberto Buchpiguel, Giovanni Guido Cerri
The new technology of PET/MRI is a prototype of hybrid imaging, allowing for the combination of molecular data from PET scanning and morphofunctional information derived from MRI scanning. Recent advances regarding the technical aspects of this device, especially after the development of MRI-compatible silicon photomultipliers of PET, permitted an increase in the diagnostic performance of PET/MRI translated into dose reduction and higher imaging quality. Among several clinical applications, PET/MRI gains ground initially in oncology, where MRI per se plays an essential role in the assessment of primary tumors (which is limited in the case of PET/CT), including prostate, rectal and gynecological tumors...
January 2018: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/29497772/sirtuins-in-the-cardiovascular-system-potential-targets-in-pediatric-cardiology
#13
Alessandro Ianni, Xuejun Yuan, Eva Bober, Thomas Braun
Cardiovascular diseases represent a major cause of death and morbidity. Cardiac and vascular pathologies develop predominantly in the aged population in part due to lifelong exposure to numerous risk factors but are also found in children and during adolescence. In comparison to adults, much has to be learned about the molecular pathways driving cardiovascular diseases in the pediatric population. Sirtuins are highly conserved enzymes that play pivotal roles in ensuring cardiac homeostasis under physiological and stress conditions...
March 2, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29484819/are-we-allowing-impact-factor-to-have-too-much-impact-the-need-to-reassess-the-process-of-academic-advancement-in-pediatric-cardiology
#14
Rohit S Loomba, Robert H Anderson
Impact factor has been used as a metric by which to gauge scientific journals for several years. A metric meant to describe the performance of a journal overall, impact factor has also become a metric used to gauge individual performance as well. This has held true in the field of pediatric cardiology where many divisions utilize impact factor of journals that an individual has published in to help determine the individual's academic achievement. This subsequently can impact the individual's promotion through the academic ranks...
March 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/29432303/utility-of-echocardiography-as-screening-for-late-onset-anthracycline-induced-cardiotoxicity-in-pediatric-cancer-survivors-observations-from-the-first-decade-after-end-of-therapy
#15
Diana J Moke, Lynn E Schubert, Heather Y Sun, Beth F Printz, Andrew C Dietz
Current screening guidelines are available for anthracycline-induced cardiotoxicity. However, the utility of echocardiogram screening for late-onset anthracycline cardiotoxicity especially in the decade immediately after end of therapy is debatable. A retrospective chart review of patients seen in the Thriving after Cancer Clinic at Rady Children's Hospital January 2006 to December 2013 was performed. Treatment data, echocardiogram results, cardiology referral notes and cardiac medication data were abstracted from anthracycline-exposed survivors...
February 9, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29406940/heart-disease-in-children
#16
REVIEW
Richard U Garcia, Stacie B Peddy
The pediatric cardiology field has developed rapidly over the past few decades. More children than ever born with congenital heart disease (CHD) are growing into adulthood. Primary care providers play a key role in diagnosis, management, and referral of children with CHD because many common cardiac complaints (eg, feeding intolerance, cyanosis, chest pain, palpitations, and syncope) are first addressed in the primary care setting. The spectrum of heart disease in children ranges from common complaints to complex single-ventricle physiology, acute myocarditis, and heart transplantation...
March 2018: Primary Care
https://www.readbyqxmd.com/read/29372615/pattern-of-inpatient-pediatric-cardiology-consultations-in-sub-saharan-africa
#17
Kriti Puri, Peter Kazembe, Treasure Mkaliainga, Msandeni Chiume, Antonio G Cabrera, Amy Sims Sanyahumbi
Malawi is one of the poorest nations in the world, ranked 151st among 195 countries by the World Bank, with an under-5-year mortality rate of 63 per 1000 live births. There are no previous studies describing the spectrum of inpatient pediatric cardiology consultations in sub-Saharan Africa. A descriptive cohort study was performed at Kamuzu Central Hospital (KCH), a tertiary care hospital in Lilongwe, Malawi. Demographic, anthropometric, and clinical information for all cardiology consults patients aged 0-18 years admitted to the children's wards over a period of 1 month was reviewed...
March 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/29329440/executive-function-and-internalizing-symptoms-in-adolescents-and-young-adults-with-congenital-heart-disease-the-role-of-coping
#18
Jamie L Jackson, Gina M Gerardo, Jennifer D Monti, Kyle A Schofield, Kathryn Vannatta
Executive functioning deficits have been documented among congenital heart disease (CHD) survivors and may contribute to emotional distress. Little research has investigated the role of coping in this association. This study examined the role of coping in accounting for the association between self-reported executive function problems and internalizing symptoms among adolescents and emerging adults (AEAs), as well as young adults (YAs) with CHD. Participants included 74 AEA ( M age  = 19.32  ±  3.47 years, range 15-25 years) and 98 YA CHD survivors ( M age  = 32...
January 10, 2018: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29286280/the-2017-seventh-world-congress-of-pediatric-cardiology-cardiac-surgery-week-in-review-electrophysiology
#19
Mitchell I Cohen, Susan Etheridge, Shubhayan Sanatani, Alpay Celiker
No abstract text is available yet for this article.
December 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/29286276/the-2017-seventh-world-congress-of-pediatric-cardiology-cardiac-surgery-week-in-review-cardiac-surgery
#20
Tom R Karl
The 2017 Seventh World Congress was held in Barcelona, Spain, 16-21 July. The week in review for this meeting is presented in the current issue of Cardiology in the Young, and herein we discuss the surgical highlights of the programme.
December 2017: Cardiology in the Young
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