keyword
MENU ▼
Read by QxMD icon Read
search

Vomiting

keyword
https://www.readbyqxmd.com/read/29928323/treatment-of-hepatic-metastases-with-computed-tomography-guided-interstitial-brachytherapy
#1
Dariusz Kieszko, Paweł Cisek, Izabela Kordzińska-Cisek, Ludmiła Grzybowska-Szatkowska
The aim of the present study was to evaluate the efficacy, safety and tolerability of local treatment of liver metastases of various types of cancer using brachytherapy with computed tomography (CT) imaging. Retrospective analysis of 61 patients with unresectable hepatic metastases treated with CT-guided interstitial high dose rate (HDR) brachytherapy of the liver between April 2014 and December 2016 was performed. Patients were treated with a single fractional dose of 15-25 Gy. Statistical analysis was performed on local relapse free survival (LRFS), progression free survival (PFS) and overall survival (OS) rates across the group...
June 2018: Oncology Letters
https://www.readbyqxmd.com/read/29926478/medi0382-a-glp-1-glucagon-receptor-dual-agonist-meets-safety-and-tolerability-endpoints-in-a-single-dose-healthy-subject-randomised-phase-1-study
#2
Philip D Ambery, Sebastian Klammt, Maximillian G Posch, Marcella Petrone, Wenji Pu, Cristina Rondinone, Lutz Jermutus, Boaz Hirshberg
AIMS: MEDI0382 is a balanced glucagon-like peptide-1/glucagon receptor dual agonist under development for the treatment of type 2 diabetes mellitus and non-alcoholic steatohepatitis. The primary objective was to assess the safety of MEDI0382 in healthy subjects. METHODS: In this placebo-controlled, double-blind, phase 1 study, healthy subjects (aged 18-45 years) were randomised (3:1) to receive a single subcutaneous dose of MEDI0382 or placebo after ≥8 hours of fasting...
June 21, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29926008/ictal-cardiorespiratory-arrest-associated-with-status-epilepticus-in-panayiotopoulos-syndrome
#3
Hirotsugu Yamamoto, Hiromichi Naito, Takaaki Osako, Kohei Tsukahara, Taihei Yamada, Tetsuya Yumoto, Atsuyoshi Iida, Yoshinori Kosaki, Makio Oka, Fumika Endo, Akira Gochi, Atsunori Nakao
A healthy 10-year-old boy vomited during sleep and later complained of abdominal pain; he became drowsy and uncommunicative. At the nearby hospital E.R., he deteriorated rapidly, and his respiratory movements were absent with cardiac arrest. He was immediately resuscitated. Brain MRI showed no abnormalities. EEG revealed an abnormal pattern with recurrent multifocal epileptiform activity over the bilateral occipital and frontal regions during sleep. Based on the clinical/radiological findings we diagnosed Panayiotopoulos syndrome (PS), a benign form of early-onset pediatric epilepsy characterized by autonomic symptoms...
June 2018: Acta Medica Okayama
https://www.readbyqxmd.com/read/29925253/using-clinical-indicators-to-reduce-perianesthesia-recovery-time-following-outpatient-tonsillectomy
#4
Habib G Zalzal, Chadi A Makary, Raquel Evans, Stacy Giardina, Tracy Underwood, Aletha Rowlands, Hassan H Ramadan
OBJECTIVE: To determine whether we could reduce the time that patients undergoing tonsillectomy are observed postoperatively without decreasing the quality of care, which would eliminate the unnecessary use of resources to monitor those patients. STUDY DESIGN: Prospective cohort. METHODS: Patients undergoing tonsillectomy were recruited for the study prior to their operation. Each patient was then monitored in perianesthesia recovery until clinical indicators for discharge readiness were met (baseline respiratory function, afebrile, ambulation per age, adequate consciousness, absence of nausea/vomiting, adequate pain control, no active bleeding, fluid toleration)...
June 1, 2018: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/29924051/consort-epidural-dexmedetomidine-improves-gastrointestinal-motility-after-laparoscopic-colonic-resection-compared-with-morphine
#5
Qiuxia Wan, Wengang Ding, Xiaoguang Cui, Xianzhang Zeng
BACKGROUND: We have previously shown that epidural dexmedetomidine, when used as an adjunct to levobupivacaine for control of postoperative pain after open colonic resection, improves recovery of gastrointestinal motility compared with morphine. METHODS: Sixty patients undergoing laparoscopic colonic resection were enrolled and allocated randomly to treatment with dexmedetomidine (group D) or morphine (group M). Group D received an epidural loading dose of dexmedetomidine (5 mL, 0...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29924009/intensity-modulated-radiotherapy-combined-with-endostar-has-similar-efficacy-but-weaker-acute-adverse-reactions-than-imrt-combined-with-chemotherapy-in-the-treatment-of-locally-advanced-nasopharyngeal-carcinoma
#6
Min Kang, Fangfang Wang, Xueyin Liao, Pingting Zhou, Rensheng Wang
The present study is to compare the efficacy and adverse effects of intensity-modulated radiotherapy (IMRT) combined with endostar and IMRT combined with concurrent chemotherapy on locally advanced nasopharyngeal carcinoma (NPC).A total of 23 patients with stage III-IVa NPC were included in the present study, and randomly divided into experimental group (10 cases treated with IMRT + endostar) and control group (13 cases treated with IMRT + chemotherapy of cis-dichlorodiamineplatinum). Endostar was intravenously administered from the first day of IMRT...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29924005/abdominal-cocoon-with-early-postoperative-small-bowel-obstruction-a-case-report-and-review-of-literature-in-china
#7
Jie Xia, WeiJia Xie, Li Chen, Daren Liu
RATIONALE: Abdominal cocoon is a condition in which intestinal obstruction results from the encasement of part or whole of the small bowel by a thick fibrous membrane, giving the appearance of a cocoon. The preoperative diagnosis is difficult to be made and the treatment is still controversial. PATIENT CONCERNS: Here we describe the case of a 62-year-old male presented with a 24-h history of continual colicky abdominal pain, which was accompanied with nausea and vomiting...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29923997/euglycemic-diabetic-ketoacidosis-caused-by-dapagliflozin-a-case-report
#8
Yu-Mou Chou, Chen-June Seak, Zhong Ning Leonard Goh, Joanna Chen-Yeen Seak, Chen-Ken Seak, Chih-Chuan Lin
RATIONALE: Diabetic ketoacidosis is a serious and potentially life-threatening acute complication of diabetes mellitus (DM). Euglycemic diabetic ketoacidosis (eDKA) is however challenging to identify in the emergency department (ED) due to absence of marked hyperglycemia, often leading to delayed diagnosis and treatment. eDKA has been recently found to be associated with sodium-glucose cotransporter 2 (SGLT2) inhibitors, one of the newest classes of antidiabetics, though there are very limited reports implicating dapagliflozin as the offending agent in ED patients...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29923992/a-phase-2-study-of-fosaprepitant-combined-with-high-dose-dexamethasone-for-japanese-cancer-patients-receiving-highly-emetogenic-chemotherapy
#9
Hozumi Kumagai, Hitoshi Kusaba, Takeharu Yamanaka, Kenta Nio, Kyoko Inadomi, Kotoe Takayoshi, Mamoru Ito, Shingo Tamura, Akitaka Makiyama, Chinatsu Makiyama, Gen Hirano, Yoshihiro Shibata, Tsuyoshi Shirakawa, Kenji Mitsugi, Hiroshi Ariyama, Taito Esaki, Koichi Akashi, Eishi Baba
PURPOSE: Combination therapy of fosaprepitant, dexamethasone (DEX) and a serotonin (5-HT3) receptor antagonist is a standard antiemetic prophylaxis for patients receiving highly emetogenic chemotherapy (HEC). However, the appropriate dose of DEX has not been established in Japan. This study determined the efficacy and safety of triplet antiemetic prophylaxis in Japanese patients receiving HEC when administered the same doses of DEX as those given in a previous international phase 3 study on this drug...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29923616/medicinal-cannabinoids-in-palliative-care
#10
REVIEW
M Agar
The treatment of symptoms in people with palliative diagnoses begins with meticulous clinical assessment with treatment choice (s) selected based on an understanding of the symptom aetiology and the evidence which underpins its treatment. Increasingly the merits of palliative care have been established earlier in the disease trajectory where treatment outcomes may include increased survival and maintenance of function. There is strong public support for the availability of medicinal cannabis, particularly for people with palliative diagnoses...
June 20, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29923298/low-incidence-of-gastrointestinal-adverse-events-over-time-with-a-fixed-ratio-combination-of-insulin-glargine-and-lixisenatide-vs-lixisenatide-alone
#11
Jennifer M Trujillo, Michelle Roberts, Terry Dex, Jason Chao, Pa-C John White, James LaSalle
This post hoc analysis of gastrointestinal (GI) adverse events (AEs) from the phase 3 LixiLan-L (NCT02058160) and LixiLan-O (NCT02058147) trials aimed to determine the frequency and timing of nausea, vomiting, and diarrhea for iGlarLixi, a titratable, fixed-ratio combination of insulin glargine 100 U/mL (iGlar) and lixisenatide, vs iGlar alone or iGlar and lixisenatide alone, in patients with type 2 diabetes uncontrolled with oral antidiabetes drugs (OADs) or basal insulin ± OADs. In iGlarLixi-treated patients, the rate of GI AEs during initial weeks of treatment was lower vs patients treated with lixisenatide alone (9...
June 19, 2018: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29923092/short-term-administration-of-mycophenolate-is-well-tolerated-in-cln3-disease-juvenile-neuronal-ceroid-lipofuscinosis
#12
Erika F Augustine, Christopher A Beck, Heather R Adams, Sara Defendorf, Amy Vierhile, Derek Timm, Jill M Weimer, Jonathan W Mink, Frederick J Marshall
Mycophenolate, an immunosuppressant, is commonly used off-label for autoimmune neurological conditions. In CLN3 disease, a neurodegenerative disorder of childhood, preclinical and clinical data suggest secondary autoimmunity and inflammation throughout the central nervous system are key components of pathogenesis. We tested the short-term tolerability of mycophenolate in individuals with CLN3 disease, in preparation for possible long-term efficacy trials of this drug. We conducted a randomized, double-blind, placebo-controlled, crossover study of mycophenolate in 19 ambulatory individuals with CLN3 disease to determine the safety and tolerability of short-term administration (NCT01399047)...
June 20, 2018: JIMD Reports
https://www.readbyqxmd.com/read/29922465/multiple-magnet-ingestion-causing-instestinal-obstruction-and-entero-enteric-fistula-which-imaging-modality-besides-radiographs-a-case-report
#13
Evangelos Blevrakis, Maria Raissaki, Sofia Xenaki, Elissavet Astyrakaki, Nelli Kholcheva, Emmanuel Chrysos
Ingested foreign bodies occur in children younger than 3 years and pass uneventfully through the gastrointestinal tract. However, multiple magnet ingestion are associated with serious complications. A 9-year old male with abdominal pain and vomiting 3 days prior to admission, underwent abdominal radiographs showing radiopaque foreign bodies. Ultrasonography (US) independently discovered one magnet floating in the jejunum. Preoperative Computed Tomography (CT) confirmed the presence of two neighbouring magnets causing obstruction and beaking of an adjacent jejunal loop...
July 2018: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/29922464/gallstone-ileus-of-the-sigmoid-colon-caused-by-cholecystocolonic-fistula-a-case-report
#14
González-Urquijo Mauricio, Hinojosa-Gonzalez David Eugenio, Quevedo-Fernandez Enrique
Introduction: A cholecystocolonic fistula (CCF) is a late complication following repeated episodes of chronic inflammation of the gallbladder in contact with the hepatic flexure, and it might cause a biliary ileus in the colon, causing an intestinal obstruction, and if left untreated, a life threatening disease. Presentation of case: a 49-year-old female patient presented with abdominal pain and bowel obstruction due to a gallstone impaction on the sigmoid colon as consequence of a cholecystocolonic fistula...
July 2018: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/29922214/clinical-features-of-headache-in-patients-with-diagnosis-of-definite-vestibular-migraine-the-vm-phenotypes-projects
#15
Roberto Teggi, Bruno Colombo, Roberto Albera, Giacinto Asprella Libonati, Cristiano Balzanelli, Angel Batuecas Caletrio, Augusto P Casani, Juan Manuel Espinosa-Sanchez, Paolo Gamba, Jose A Lopez-Escamez, Sergio Lucisano, Marco Mandalà, Giampiero Neri, Daniele Nuti, Rudi Pecci, Antonio Russo, Eduardo Martin-Sanz, Ricardo Sanz, Gioacchino Tedeschi, Paola Torelli, Paolo Vannucchi, Giancarlo Comi, Mario Bussi
Migraine is a common neurological disorder characterized by episodic headaches with specific features, presenting familial aggregation. Migraine is associated with episodic vertigo, named Vestibular Migraine (VM) whose diagnosis mainly rely on clinical history showing a temporary association of symptoms. Some patient refers symptoms occurring in pediatric age, defined "episodic symptoms which may be associated with migraine." The aim of this cross sectional observational study was to assess migraine-related clinical features in VM subjects...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29921320/phase-ia-study-of-the-indoleamine-2-3-dioxygenase-1-ido1-inhibitor-navoximod-gdc-0919-in-patients-with-recurrent-advanced-solid-tumors
#16
Asha Nayak-Kapoor, Zhonglin Hao, Ramses Sadek, Robin Dobbins, Lisa Marshall, Nicholas N Vahanian, W Jay Ramsey, Eugene Kennedy, Mario R Mautino, Charles J Link, Ray S Lin, Stephanie Royer-Joo, Xiaorong Liang, Laurent Salphati, Kari M Morrissey, Sami Mahrus, Bruce McCall, Andrea Pirzkall, David H Munn, John E Janik, Samir N Khleif
BACKGROUND: Indoleamine-2,3-dioxygenase 1 (IDO1) catalyzes the oxidation of tryptophan into kynurenine and is partially responsible for acquired immune tolerance associated with cancer. The IDO1 small molecule inhibitor navoximod (GDC-0919, NLG-919) is active as a combination therapy in multiple tumor models. METHODS: This open-label Phase Ia study assessed safety, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary anti-tumor activity of navoximod in patients with recurrent/advanced solid tumors, administered as 50-800 mg BID on a 21/28 day and at 600 mg on a 28/28 day schedule...
June 20, 2018: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/29921056/-multimodal-analgesic-analgesia-in-patients-with-obstructive-sleep-apnea-hypopnea-syndrome-with-multiple-planar-surgery
#17
J Su, J H Tian, X X Gao, Y F Wu, J M Zu, K F Dong, L G Duan
Objective: To observe the value of multimodal analgesia in patients with OSAHS undergoing multiplanar surgery. Method: A total number of 90 patients with obstructive sleep apnea hypopnea syndrome with tongue hypertrophy or hyperplasia of the root lymphoid tissue were collected. All patients underwent improved uvulatopharyngeal angioplasty (H-UPPP) and tongue root partial resection, or simultaneous tongue ablation at the same time, and they were randomly divided into two groups,45 patients in each group.In multi-modal analgesic group, the parrixibub sodium 40 mg were given intravenously 0...
June 5, 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29920955/nimotuzumab-combined-with-chemotherapy-as-first-line-treatment-for-advanced-lung-squamous-cell-carcinoma
#18
Xiaoyan Si, Shafei Wu, Hanping Wang, Xiaotong Zhang, Mengzhao Wang, Xuan Zeng, Li Zhang
BACKGROUND: This study was conducted to evaluate the efficacy and safety of nimotuzumab combined with chemotherapy as first-line therapy in advanced lung squamous cell carcinoma (LSCC), and to explore predictive biomarkers of the efficacy of nimotuzumab. METHODS: A retrospective study was conducted of patients with advanced LSCC administered nimotuzumab combined with chemotherapy as first-line therapy from June 2012 to December 2016 at the Department of Respiratory Medicine, Peking Union Medical College Hospital...
June 19, 2018: Thoracic Cancer
https://www.readbyqxmd.com/read/29920726/an-expert-consensus-to-standardise-definitions-diagnosis-and-treatment-targets-for-anti-fibrotic-stricture-therapies-in-crohn-s-disease
#19
F Rieder, D Bettenworth, C Ma, C E Parker, L A Williamson, S A Nelson, G van Assche, A Di Sabatino, Y Bouhnik, R W Stidham, A Dignass, G Rogler, S A Taylor, J Stoker, J Rimola, M E Baker, J G Fletcher, J Panes, W J Sandborn, B G Feagan, V Jairath
BACKGROUND: Fibrotic stricture is a common complication of Crohn's disease (CD) affecting approximately half of all patients. No specific anti-fibrotic therapies are available; however, several therapies are currently under evaluation. Drug development for the indication of stricturing CD is hampered by a lack of standardised definitions, diagnostic modalities, clinical trial eligibility criteria, endpoints and treatment targets in stricturing CD. AIM: To standardise definitions, diagnosis and treatment targets for anti-fibrotic stricture therapies in Chron's disease...
June 19, 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29917106/microsurgical-clipping-of-ruptured-distal-posterior-inferior-cerebellar-artery-aneurysm-3-dimensional-operative-video
#20
Ricardo Chmelnitsky Wainberg, Marcos Devanir Silva da Costa, Yair A Ugalde Hernández, Ricardo Lourenço Caramanti, César Augusto Ferreira Alves Filho, Helbert Palmiero, Ricardo Pagung Saick, Feres Chaddad-Neto
The distal posterior inferior cerebellar artery (PICA) is a rare site of aneurysm formation. Only small case series and case reports regarding surgical treatment are found in the literature.The PICA is divided into 5 segments (anterior medullary, lateral medullary, tonsilomedullary, telovelotonsillary, and cortical), and the distal ones represent the most complex, due to anatomic variations. We present a case of a 69-yr-old female patient who has suffered from a sudden and intense occipital headache, associated with nausea and vomiting...
June 18, 2018: Operative Neurosurgery (Hagerstown, Md.)
keyword
keyword
713
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"