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AYA oncology

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https://www.readbyqxmd.com/read/28417170/reduced-dose-ct-with-model-based-iterative-reconstruction-compared-to-standard-dose-ct-of-the-chest-abdomen-and-pelvis-in-oncology-patients-intra-individual-comparison-study-on-image-quality-and-lesion-conspicuity
#1
Linda Nayeli Morimoto, Aya Kamaya, Isabelle Boulay-Coletta, Dominik Fleischmann, Lior Molvin, Lu Tian, George Fisher, Jia Wang, Jürgen K Willmann
PURPOSE: To compare image quality and lesion conspicuity of reduced dose (RD) CT with model-based iterative reconstruction (MBIR) compared to standard dose (SD) CT in patients undergoing oncological follow-up imaging. METHODS: Forty-four cancer patients who had a staging SD CT within 12 months were prospectively included to undergo a weight-based RD CT with MBIR. Radiation dose was recorded and tissue attenuation and image noise of four tissue types were measured...
April 17, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28376686/-stories-take-your-role-away-from-you-understanding-the-impact-on-health-care-professionals-of-viewing-digital-stories-of-pediatric-and-adolescent-young-adult-oncology-patients
#2
Catherine M Laing, Nancy J Moules, Andrew Estefan, Mike Lang
The purpose of this philosophical hermeneutic study was to understand the effects on health care providers (HCPs) of watching digital stories made by (past and present) pediatric and adolescent/young adult (AYA) oncology patients. Twelve HCPs participated in a focus group where they watched digital stories made by pediatric/AYA oncology patients and participated in a discussion related to the impact the stories had on them personally and professionally. Findings from this research revealed that HCPs found digital stories to be powerful, therapeutic, and educational tools...
April 1, 2017: Journal of Pediatric Oncology Nursing: Official Journal of the Association of Pediatric Oncology Nurses
https://www.readbyqxmd.com/read/28370975/international-evolution-in-aya-oncology-current-status-and-future-expectations
#3
REVIEW
Andrea Ferrari, Ronald D Barr
Adolescents and Young Adults (AYAs) contribute approximately 1 million incident cases globally, but the great majority are underserved. In high-income countries, overall survival exceeds 80%, but the needs of this population during and after their treatment experience are poorly met, though specialized clinical programs are evolving. Engagement of national governments is advantageous and deployment of multidisciplinary teams essential. Collaboration between pediatric and adult healthcare providers is mandatory and AYAs must be given a strong voice in program development...
March 30, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28244694/global-assessment-of-cancer-incidence-and-survival-in-adolescents-and-young-adults
#4
Archie Bleyer, Andrea Ferrari, Jeremy Whelan, Ronald D Barr
In high-income countries, cancer remains the commonest cause of disease-related death in adolescents and young adults (AYAs) despite survival improvements. With more than 1,000,000 new diagnoses of cancer in AYAs annually worldwide, and their number of life-years affected by cancer being greatest of all ages, the global burden of cancer in AYAs exceeds that in all other ages. In low- and middle-income countries, where the great majority of the world's 3 billion AYAs reside, the needs of those with cancer have been identified and demand attention...
February 28, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28241089/adolescent-and-young-adult-oncology-patients-disparities-in-access-to-specialized-cancer-centers
#5
Elysia Alvarez, Theresa Keegan, Emily E Johnston, Robert Haile, Lee Sanders, Olga Saynina, Lisa J Chamberlain
BACKGROUND: Adolescents and young adults (AYAs) ages 15 to 39 years with cancer continue to experience disparate survival outcomes compared with their younger and older counterparts. This may be caused in part by differential access to specialized cancer centers (SCCs), because treatment at SCCs has been associated with improved overall survival. The authors examined social and clinical factors associated with AYA use of SCCs (defined as Children's Oncology Group-designated or National Cancer Institute-designated centers)...
February 27, 2017: Cancer
https://www.readbyqxmd.com/read/28209594/adolescents-and-young-adults-with-acute-lymphoblastic-leukemia-and-acute-myeloid-leukemia-impact-of-care-at-specialized-cancer-centers-on-survival-outcome
#6
Julie Wolfson, Can-Lan Sun, Laura Wyatt, Wendy Stock, Smita Bhatia
Background: Adolescents and young adults (AYA; 15-39 years) with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) experience inferior survival when compared with children. Impact of care at NCI-designated Comprehensive Cancer Centers (CCC) or Children's Oncology Group sites (COG) on survival disparities remains unstudied.Methods: Using the Los Angeles cancer registry, we identified 1,870 ALL or AML patients between 1 and 39 years at diagnosis. Cox regression analyses assessed risk of mortality; younger age + CCC/COG served as the referent group...
February 16, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28155019/the-positive-effect-of-a-dedicated-adolescent-and-young-adult-fertility-program-on-the-rates-of-documentation-of-therapy-associated-infertility-risk-and-fertility-preservation-options
#7
Jeremy Lewin, Justin Ming Zheng Ma, Laura Mitchell, Seline Tam, Natasha Puri, Derek Stephens, Amirrtha Srikanthan, Philippe Bedard, Albiruni Razak, Michael Crump, David Warr, Meredith Giuliani, Abha Gupta
PURPOSE: Minimal data exist regarding documentation of therapy-associated infertility risk (IR) and fertility preservation (FP) options during the initial oncology consultation prior to systemic therapy. This study investigated factors affecting IR/FP documentation and assessed the effect of implementation of an Adolescent and Young Adult (AYA) program on documentation rates. METHODS: A retrospective review of charts of patients receiving gonadotoxic therapy was undertaken for documentation of IR/FP pre- and post-implementation of an AYA program...
February 2, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28129743/life-situation-and-psychosocial-care-of-adolescent-and-young-adult-aya-cancer-patients-study-protocol-of-a-12-month-prospective-longitudinal-study
#8
Katja Leuteritz, Michael Friedrich, Erik Nowe, Annekathrin Sender, Yve Stöbel-Richter, Kristina Geue
BACKGROUND: In recent years, there has been an increased research focus on adolescent and young adult (AYA) cancer patients. Few longitudinal studies have taken into consideration the specifics of their life situation and the status of psychosocial care services for this population. Our ongoing study aims to determine the psychosocial life and supportive care situation of AYA cancer patients, to describe risk groups, and to develop recommendations for their psycho-oncological care and support...
January 28, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28080182/multi-professional-perspectives-on-adolescent-and-young-adult-oncology-across-europe-an-e-delphi-survey
#9
Simon A Pini, Faith Gibson, Lorna A Fern, Sue J Morgan, Robert S Phillips, Dan P Stark
The aims of this article are to describe the ongoing development of adolescent and young adult (AYA) cancer services within the European Union (EU), and to develop consensus on key areas within the field. This survey used an e-Delphi design. An initial survey was distributed via email to professionals working in Europe. A snowball sampling technique was used to promote distribution. Consensus was sought over three rounds from October 2012 to April 2015. Consensus was defined as >80% agreement ("agree" or "strongly agree")...
March 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28051344/trends-in-cancer-mortality-among-adolescents-and-young-adults-in-brazil
#10
Nathalie Vieira Balmant, Rejane de Souza Reis, Marceli de Oliveira Santos, Julio Pinto Oliveira, Beatriz de Camargo
PURPOSE: Adolescents and young adults (AYA) with cancer comprise an intermediate age group between pediatric and adult oncology, and have a spectrum of different types of cancers. Survival among this group has not improved as much as in younger children with cancer. The aim of this study was evaluate the trends in cancer mortality of AYA aged 15-29 years in Brazil. METHODS: Data were extracted from the Atlas of Cancer Mortality databases from 1979 to 2013. Age-specific mortality rates were calculated based on the deaths from each type of cancer and the period via a direct method using the proposed world population age groups...
January 4, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28040718/promoting-the-shared-care-model-for-adolescent-and-young-adults-with-cancer-optimizing-referrals-and-care-coordination-with-primary-care-providers
#11
Karen E Kinahan, Sheetal Kircher, Jessica Altman, Alfred Rademaker, John M Salsman, Aarati Didwania, Bridget O'Brien, Alpa C Patel, Stacy D Sanford
BACKGROUND: The "shared-care model" for patients with cancer involves care coordination between primary care providers (PCPs) and oncologists, with the goal of optimizing survivorship care. However, a high proportion of adolescent and young adult (AYA) cancer survivors do not have a PCP. Study objectives were to increase the percentage of AYAs with a PCP documented in the electronic medical record (EMR) via the use of a best practice advisory (BPA) or "stopgap" intervention; to increase communication between providers by the number of routed clinic notes; and to assess oncology providers' attitudes/beliefs about the model and intervention...
January 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/27995449/cytoreductive-surgery-and-hyperthermic-intraperitoneal-chemoperfusion-in-adolescent-and-young-adults-with-peritoneal-metastases
#12
Mashaal Dhir, Lekshmi Ramalingam, Yongli Shuai, Sam Pakrafter, Heather L Jones, Melissa E Hogg, Amer H Zureikat, Matthew P Holtzman, Steven A Ahrendt, Nathan Bahary, James F Pingpank, Herbert J Zeh, David L Bartlett, Haroon A Choudry
BACKGROUND: Several studies suggest that young patients may derive less oncologic benefit from surgical resection of cancers compared with older patients. We hypothesized that young patients may have worse outcomes following cytoreductive surgery with hyperthermic intraperitoneal chemoperfusion (CRS/HIPEC) for peritoneal metastases. METHODS: Perioperative and oncologic outcomes in adolescent and young adults (AYA), defined as younger than age 40 years (n = 135), undergoing CRS/HIPEC between 2001 and 2015 were reviewed and compared with middle-aged adults, defined as aged 40-65 years (n = 684)...
December 19, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27983882/building-a-national-framework-for-adolescent-and-young-adult-hematology-and-oncology-and-transition-from-pediatric-to-adult-care-report-of-the-inaugural-meeting-of-the-ajet-working-group-of-the-german-society-for-pediatric-oncology-and-hematology
#13
Gabriele Escherich, Stefan Bielack, Stephan Maier, Ralf Braungart, Tim H Brümmendorf, Mathias Freund, Regine Grosse, Anette Hoferer, Rebecca Kampschulte, Barbara Koch, Melchior Lauten, Valeria Milani, Henning Ross, Freimut Schilling, Dieter Wöhrle, Holger Cario, Uta Dirksen
Adolescents and young adults (AYAs) with hemato-oncological problems constitute a heterogenous group with characteristic particularities, specific needs, and age-related clinical and unique psychosocial features. Strong collaboration between pediatric and adult hemato-oncology settings is essential to address their needs appropriately. This is not only true for patients who first become ill during adolescence or young adulthood, but equally so for people who contract hemato-oncological diseases congenitally or as younger children and who are now becoming old enough to leave the pediatric setting and have to transit into "adult" medical care...
December 16, 2016: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/27863724/-which-approach-of-therapeutic-education-te-for-adolescents-and-young-adults-with-cancer-experience-from-the-te-working-group-of-go-aja
#14
Nadège Corradini, Loïc Dagorne, Marielle Retailleau, Françoise Rédini, Hélène Sudour-Bonnange, Leila Gofti-Laroche, Anne Le Rhun, Nathalie Gaspar
INTRODUCTION: Therapeutic education (TE) is a practice developed over 40 years at an international level to give people with chronic illness the skills necessary to help them better manage their disease. The lengthening survival time of cancer patients as well as changes in the patient-caregiver relationship have contributed to the development of TE in oncologic diseases. Every year in France, about 1900 adolescents and young adults (15-25 years old) are diagnosed with cancer which is the second leading cause of death in this age group...
December 2016: Bulletin du Cancer
https://www.readbyqxmd.com/read/27779446/a-comparison-of-extremity-thrombosis-rates-in-adolescent-and-young-adult-versus-younger-pediatric-oncology-patients-at-a-children-s-hospital
#15
James D Cooper, Aimee G Costello, Peter H Shaw
PURPOSE: To examine whether the rates of thrombosis in children (≤14 years of age) and adolescent/young adult (AYA) patients (15-22 years of age) with cancer is different. METHODS: We retrospectively studied the rates of thrombosis in children and AYA patients at the Children's Hospital of Pittsburgh during the years 2002-2010, using the tumor registry database. This list was then divided into two groups based on age at diagnosis. A review of ICD-9 codes from hospital billing records was then performed to identify patients who carried diagnoses of cancer (140...
March 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/27671919/improving-access-to-standardized-fertility-preservation-information-for-older-adolescents-and-young-adults-with-cancer-using-a-user-centered-approach-with-young-adult-patients-survivors-and-partners-to-refine-fertility-knowledge-transfer
#16
Seline Tam, Natasha Puri, Derek Stephens, Laura Mitchell, Meredith Giuliani, Janet Papadakos, Abha A Gupta
Adolescent and young adult (AYA) cancer patients under 40 should be made aware of their fertility risks and preservation options throughout their care. However, discussions on fertility preservation (FP) do not routinely occur. With a dearth of FP resources, oncology providers may lack knowledge around FP. Thus, informational needs can be unmet, leading to anxiety and distress in patients. Provision of pertinent and timely information can help patients cope better with their diagnosis. FP pamphlets were developed for men and women with cancer...
September 27, 2016: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/27606308/model-of-care-for-adolescents-and-young-adults-with-cancer-the-youth-project-in-milan
#17
Chiara Magni, Laura Veneroni, Matteo Silva, Michela Casanova, Stefano Chiaravalli, Maura Massimino, Carlo Alfredo Clerici, Andrea Ferrari
Adolescents and young adults (AYA) with cancer form a particular group of patients with unique characteristics, who inhabit a so-called "no man's land" between pediatric and adult services. In the last 10 years, the scientific oncology community has started to pay attention to these patients, implementing dedicated programs. A standardized model of care directed toward patients in this age range has yet to be developed and neither the pediatric nor the adult oncologic systems perfectly fit these patients' needs...
2016: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/27595356/collaboration-and-networking
#18
O Husson, E Manten-Horst, W T A van der Graaf
Awareness of the need for collaboration across pediatric and adult cancer to care for adolescents and young adults (AYAs) arose from the recognition of the unique characteristics of AYAs with cancer. Neither pediatric nor adult oncology hospital departments are able to provide age-appropriate care single handedly. The best way to bridge the gap in care of AYA cancer patients is to centralize aspects of their care within dedicated AYA care programs, including the following essential components: provision of developmentally appropriate and multidisciplinary (supportive) care, availability of AYA inpatient and outpatient facilities and healthcare professional AYA expertise as collaboration between adult and pediatric departments...
2016: Progress in Tumor Research
https://www.readbyqxmd.com/read/27554940/measuring-the-efficacy-of-a-project-for-adolescents-and-young-adults-with-cancer-a-study-from-the-milan-youth-project
#19
Andrea Ferrari, Matteo Silva, Laura Veneroni, Chiara Magni, Carlo Alfredo Clerici, Cristina Meazza, Monica Terenziani, Filippo Spreafico, Stefano Chiaravalli, Michela Casanova, Roberto Luksch, Serena Catania, Elisabetta Schiavello, Veronica Biassoni, Marta Podda, Luca Bergamaschi, Nadia Puma, Alice Indini, Tullio Proserpio, Maura Massimino
BACKGROUND: Various projects dedicated specifically to adolescents and young adults (AYA) with cancer have been developed in recent years. A critical aspect of such programs is the ability to demonstrate its value, and therefore how to measure desired outcomes. METHODS: A list of metrics to consider for demonstrating the advantages of an AYA program was identified and used to assess the activity of the Youth Project operating at the Pediatric Oncology Unit of the Istituto Nazionale Tumori in Milan...
August 24, 2016: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/27529573/a-review-of-the-oncology-patient-s-challenges-for-utilizing-fertility-preservation-services
#20
Dina M Flink, Jeanelle Sheeder, Laxmi A Kondapalli
PURPOSE: The American Society of Clinical Oncology issued practice guidelines in 2006 to provide critical information about fertility impact to adolescents and young adults (AYA) at the time of cancer diagnosis. Survivors continue to express concerns about their long-term reproductive health after cancer therapy even as treatment options for fertility preservation evolve. An underutilization of fertility preservation methods by cancer patients continues to persist. A review of the literature cites barriers and challenges that limit fertility information and preservation options for AYA cancer patients...
March 2017: Journal of Adolescent and Young Adult Oncology
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