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https://www.readbyqxmd.com/read/28524073/parents-attitudes-toward-clinical-genetic-testing-for-autism-spectrum-disorder-data-from-a-norwegian-sample
#1
Jarle Johannessen, Terje Nærland, Sigrun Hope, Tonje Torske, Anne Lise Høyland, Jana Strohmaier, Arvid Heiberg, Marcella Rietschel, Srdjan Djurovic, Ole A Andreassen
Clinical genetic testing (CGT) of children with autism spectrum disorder (ASD) may have positive and negative effects. Knowledge about parents' attitudes is needed to ensure good involvement of caregivers, which is crucial for accurate diagnosis and effective clinical management. This study aimed to assess parents' attitudes toward CGT for ASD. Parent members of the Norwegian Autism Society were given a previously untested questionnaire and 1455 answered. Linear regression analyses were conducted to evaluate contribution of parent and child characteristics to attitude statements...
May 18, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28523966/relationship-centered-dementia-care-insights-from-a-community-based-culture-change-coalition
#2
Lorna de Witt, Darla Fortune
This article reports on the work of a community-based culture change coalition affiliated with the Partnerships in Dementia Care Alliance, a research network committed to strengthening dementia care through supporting relationship-centered care approaches. Research to date emphasizes negative aspects of dementia care relationships. Drawing on data the culture change coalition collected as part of their culture change work using participatory action research guided by appreciative inquiry, this article examines what relationship qualities contributed to positive dementia care experiences and how positive relationships were created...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/28514670/radiation-safety-in-children-with-congenital-and-acquired-heart-disease-a-scientific-position-statement-on-multimodality-dose-optimization-from-the-image-gently-alliance
#3
REVIEW
Kevin D Hill, Donald P Frush, B Kelly Han, Brian G Abbott, Aimee K Armstrong, Robert A DeKemp, Andrew C Glatz, S Bruce Greenberg, Alexander Sheldon Herbert, Henri Justino, Douglas Mah, Mahadevappa Mahesh, Cynthia K Rigsby, Timothy C Slesnick, Keith J Strauss, Sigal Trattner, Mohan N Viswanathan, Andrew J Einstein
There is a need for consensus recommendations for ionizing radiation dose optimization during multi-modality medical imaging in children with congenital and acquired heart disease (CAHD). These children often have complex diseases and may be exposed to a relatively high cumulative burden of ionizing radiation from medical imaging procedures including cardiac computed tomography, nuclear cardiology studies and fluoroscopically guided diagnostic and interventional catheterization and electrophysiology procedures...
May 17, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28513531/who-should-lead-a-trauma-team-surgeon-or-non-surgeon-a-systematic-review-and-meta-analysis
#4
Shahab Hajibandeh, Shahin Hajibandeh
BACKGROUND: Presence of a trauma team leader (TTL) in the trauma team is associated with positive patient outcomes in major trauma. The TTL is traditionally a surgeon who coordinates the resuscitation and ensures adherence to Advanced Trauma Life Support (ATLS) guidelines. The necessity of routine surgical leadership in the resuscitative component of trauma care has been questioned by some authors. Therefore, it remains controversial who should lead the trauma team. We aimed to evaluate outcomes associated with surgeon versus non-surgeon TTLs in management of trauma patients...
June 1, 2017: Journal of Injury & Violence Research
https://www.readbyqxmd.com/read/28512551/consensus-statements-and-clinical-recommendations-on-treatment-indications-surgical-procedures-prosthetic-protocols-and-complications-following-all-on-4-standard-treatment-9th-mozo-grau-ticare-conference-in-quintanilla-spain
#5
REVIEW
Miguel Penarrocha-Diago, María Penarrocha-Diago, Regino Zaragozí-Alonso, David Soto-Penaloza, Meeting On Behalf Of The Ticare Consensus
OBJECTIVES: The present consensus report critically evaluates the scientific evidence based on a comprehensive systematic review of the All-On-4 treatment concept, focusing primarily on the treatment indications, surgical procedures and prosthetic protocols, and secondarily on the mechanical and biological complications involved. MATERIAL AND METHODS: A systematic review was made in advance of the meeting. Consensus statements, treatment guidelines and recommendations for future research were based on within-group as well as plenary debates and discussions of the systematic review...
May 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28509565/a-qualitative-meta-summary-using-sandelowski-and-barroso-s-method-for-integrating-qualitative-research-to-explore-barriers-and-facilitators-to-self-care-in-heart-failure-patients
#6
Oliver Rudolf Herber, Bettina Bücker, Maria-Inti Metzendorf, Julie Barroso
BACKGROUND: Individual qualitative studies provide varied reasons for why heart failure patients do not engage in self-care, yet articles that aggregated primary studies on the subject have methodological weaknesses that justified the execution of a qualitative meta-summary. AIM: The aim of this study is to integrate the findings of qualitative studies pertaining to barriers and facilitators to self-care using meta-summary techniques. METHODS: Qualitative meta-summary techniques by Sandelowski and Barroso were used to combine the findings of qualitative studies...
May 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28498779/evaluation-of-the-education-clinical-telemedicine-e-health-in-the-curriculum-of-medical-students-at-the-university-of-zurich
#7
Christiane Brockes, Thomas Grischott, Magdalena Dutkiewicz, Sabine Schmidt-Weitmann
BACKGROUND: Digitalization and patient empowerment result in new requirements and challenges. In response, the module "Clinical Telemedicine/e-Health" was implemented by the Faculty of Medicine of Zurich in 2008. The module was systematically evaluated to determine if the students would benefit from this course. In 2011, 2015, and 2016 further evaluations were performed. METHOD: In 2008 and 2009, students evaluated 16 statements. We calculated the combined mean value and medians for both evaluations...
May 12, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/28497912/testosterone-replacement-therapy-long-term-safety-and-efficacy
#8
REVIEW
Giovanni Corona, Alessandra Sforza, Mario Maggi
Recent position statements and guidelines have raised the distinction between a true and false, age-related hypogonadism (HG) or late-onset hypogonadism (LOH). The former is the consequence of congenital or acquired "organic" damage of the brain centers or of the testis. The latter is mainly secondary to age-related comorbidities and does not require testosterone (T) therapy (TTh). In addition, concerns related to cardiovascular (CV) safety have further increased the scepticism related to TTh. In this paper, we reviewed the available evidence supporting the efficacy of TTh in non-organic HG and its long term safety...
April 30, 2017: World Journal of Men's Health
https://www.readbyqxmd.com/read/28495861/testosterone-treatment-and-cardiovascular-and-venous-thromboembolism-risk-what-is-new
#9
G Corona, M Dicuio, G Rastrelli, E Maseroli, F Lotti, A Sforza, M Maggi
In men, testosterone (T) production declines as a function of ageing. Late-onset hypogonadism (LOH) is the most commonly used term to indicate this age-related condition. In LOH, the relative clinical significance and the potential benefit of testosterone treatment (TTh) are still the subject of strong criticisms in the scientific community. The debate is further complicated by the recent position statement of the US Food and Drug Administration (FDA) emphasizing that, in LOH, the benefits and safety of TTh have not been fully established...
May 10, 2017: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
https://www.readbyqxmd.com/read/28495452/society-of-interventional-radiology-position-statement-on-parental-leave
#10
Meridith J Englander, Christine E Ghatan, Barbara Nickel Hamilton, Shellie C Josephs, Kari J Nelson, Laura E Traube
No abstract text is available yet for this article.
May 9, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28493226/-etiology-and-pathophysiology-of-fibromyalgia-syndrome-updated-guidelines-2017-overview-of-systematic-review-articles-and-overview-of-studies-on-small-fiber-neuropathy-in-fms-subgroups
#11
N Üçeyler, M Burgmer, E Friedel, W Greiner, F Petzke, M Sarholz, M Schiltenwolf, A Winkelmann, C Sommer, W Häuser
BACKGROUND: The regular update of the guidelines on fibromyalgia syndrome, AWMF number 145/004, was planned for April 2017. METHODS: The guidelines were developed by 13 scientific societies and 2 patient self-help organizations coordinated by the German Pain Society. Working groups (n =8) with a total of 42 members were formed balanced with respect to gender, medical expertise, position in the medical or scientific hierarchy and potential conflicts of interest...
May 10, 2017: Der Schmerz
https://www.readbyqxmd.com/read/28489677/futility-of-imaging-to-stage-melanoma-patients-with-a-positive-sentinel-lymph-node
#12
Lodewijka H J Holtkamp, Rebecca L Read, Louise Emmett, John F Thompson, Omgo E Nieweg
The use of staging imaging in melanoma patients with a positive sentinel lymph node (SLN) has been reported to be of limited value. Improved accuracy resulting from the development of time-of-flight positron emission tomography (PET) and ongoing image quality improvement of computed tomography (CT) may challenge this statement. Our retrospective study assessed the clinical value of routine staging CT and PET/CT imaging in a recent cohort of asymptomatic SLN-positive patients. Between January 2011 and April 2014, 143 patients with a positive SLN were routinely staged using CT of various parts of the body or whole-body PET/CT...
May 4, 2017: Melanoma Research
https://www.readbyqxmd.com/read/28489290/obesity-a-chronic-relapsing-progressive-disease-process-a-position-statement-of-the-world-obesity-federation
#13
EDITORIAL
G A Bray, K K Kim, J P H Wilding
This paper considers the argument for obesity as a chronic relapsing disease process. Obesity is viewed from an epidemiological model, with an agent affecting the host and producing disease. Food is the primary agent, particularly foods that are high in energy density such as fat, or in sugar-sweetened beverages. An abundance of food, low physical activity and several other environmental factors interact with the genetic susceptibility of the host to produce positive energy balance. The majority of this excess energy is stored as fat in enlarged, and often more numerous fat cells, but some lipid may infiltrate other organs such as the liver (ectopic fat)...
May 10, 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28483426/diabetes-and-anemia-international-diabetes-federation-idf-southeast-asian-region-sear-position-statement
#14
REVIEW
Manisha Sahay, Sanjay Kalra, Rajesh Badani, Ganapathi Bantwal, Anil Bhoraskar, A K Das, Bharati Dhorepatil, Sujoy Ghosh, Tarun Jeloka, Deepak Khandelwal, Zafar Ahmed Latif, Milind Nadkar, Md Faruque Pathan, Banshi Saboo, Rakesh Sahay, Suleiman Shimjee, Dina Shrestha, Ali Siyan, Shamim Hayder Talukdar, Mangesh Tiwaskar, A G Unnikrishnan
Anemia is often associated with diabetes mellitus and is known to intensify the risk of developing diabetes-related microvascular and macrovascular complications. There is paucity in understanding of co-existence of these conditions, especially in Southeast Asian countries. Iron and/or erythropoietin deficiencies are the major causes of anemia in diabetes, and diabetic kidney disease plays a key role. Patients with diabetes need to be screened for anemia along with other risk factors and anemia should be corrected appropriately to improve overall clinical outcomes...
April 28, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28474488/a-q-methodology-study-to-investigate-the-experiences-of-head-and-neck-cancer-patients-from-diagnosis-to-1%C3%A2-year
#15
K J Reid, A Swift, H Mehanna
The experiences of disease and treatment for patients diagnosed with head and neck cancer (H&NC) are known to be important indicators of the quality of care but are represented poorly in the literature. Survival is a major outcome measure to which health-related quality of life (HRQoL) adds detail but outcomes are not fully representative of the patients' experiences because quality of care and reality of treatment are overlooked. This study explored the HRQoL, quality of care and reality of treatment themes using a mixed-methods approach, Q Methodology...
May 4, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28469570/a-framework-for-collaborative-curation-of-neuroscientific-literature
#16
Christian O'Reilly, Elisabetta Iavarone, Sean L Hill
Large models of complex neuronal circuits require specifying numerous parameters, with values that often need to be extracted from the literature, a tedious and error-prone process. To help establishing shareable curated corpora of annotations, we have developed a literature curation framework comprising an annotation format, a Python API (NeuroAnnotation Toolbox; NAT), and a user-friendly graphical interface (NeuroCurator). This framework allows the systematic annotation of relevant statements and model parameters...
2017: Frontiers in Neuroinformatics
https://www.readbyqxmd.com/read/28467213/interstitial-pneumonia-with-autoimmune-features-value-of-histopathology
#17
Ayodeji Adegunsoye, Justin M Oldham, Eleanor Valenzi, Cathryn Lee, Leah J Witt, Lena Chen, Steven Montner, Jonathan H Chung, Imre Noth, Rekha Vij, Mary E Strek, Aliya N Husain
CONTEXT: - Patients with idiopathic interstitial pneumonia may display evidence of autoimmunity, without meeting criteria for a defined connective tissue disease. A recent European Respiratory Society/American Thoracic Society statement proposed research criteria for interstitial pneumonia with autoimmune features (IPAF), which includes findings from the clinical, serologic, and morphologic domains. OBJECTIVES: - To investigate the importance of histopathologic criteria within the morphologic domain and to report our methodology for identifying these features...
May 3, 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28463852/substance-use-among-nurses-and-nursing-students-a-joint-position-statement-of-the-emergency-nurses-association-and-the-international-nurses-society-on-addictions
#18
Stephen Strobbe, Melanie Crowley
Alcohol and other substance use by nurses potentially places patients, the public, and nurses themselves at risk for serious injury or death. Nursing students are also at risk for problems related to substance use. When viewed and treated as a chronic medical illness, treatment outcomes for substance use disorders are comparable with those of other diseases and can result in lasting benefits. Professional monitoring programs that employ an alternative-to-discipline approach have been shown to be effective in the treatment of health professionals with substance use disorders and are considered a standard for recovery, with high rates of completion and return to practice...
May 2, 2017: Journal of Addictions Nursing
https://www.readbyqxmd.com/read/28462647/laboratory-risk-indicator-for-necrotising-fasciitis-lrinec-score-for-the-assessment-of-early-necrotising-fasciitis-a-systematic-review-of-the-literature
#19
J Bechar, S Sepehripour, J Hardwicke, G Filobbos
Introduction Early operative debridement of necrotising fasciitis is a major outcome determinant. Identification and diagnosis of such patients can be clinically difficult. The Laboratory Risk Indicator for Necrotising Fasciitis (LRINEC) score first published in 2004 is based on routinely performed parameters and offers a method for identifying early cases. No literature review has yet been performed on the application of such a score. Methods A systematic review of English-language literature was performed from 2004 to 2014 to identify articles reporting use of LRINEC score and the incidence of necrotising fasciitis...
May 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28462545/indian-college-of-physicians-icp-position-statement-on-pharmacovigilance
#20
Puneet Dhamija, Sanjay Kalra, Pramod Kumar Sharma, V Kalaiselvan, A Muruganathan, Yatan Pal Singh Balhara, Rajesh Badani, Ganapathi Bantwal, A K Das, Bharati Dhorepatil, Sujoy Ghosh, Tarun Jeloka, Deepak Khandelwal, Milind Y Nadkar, Kuppili Pooja Patnaik, Banshi Saboo, Manisha Sahay, Rakesh Sahay, Mangesh Tiwaskar, A G Unnikrishnan
Pharmacovigilance is the art and science of detection, understanding and prevention of adverse drug reactions and not merely a critical analysis of prescriptions and errors. This field starts with reporting by clinicians of a suspected adverse drug reaction (ADR) to the pharmacologist followed by joint causality analysis and ends at the application of new information by a clinician for benefit of patients. There are a number of ways, which can be utilised for reporting adverse effects using pen and paper format to software applications for smart phones...
March 2017: Journal of the Association of Physicians of India
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