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https://www.readbyqxmd.com/read/28229280/posterior-urethral-valve-in-fetuses-evidence-for-the-role-of-inflammatory-molecules
#1
Érica Leandro Marciano Vieira, Natalia Pessoa Rocha, Fernando Macedo Bastos, Kátia Daniela da Silveira, Alamanda K Pereira, Eduardo Araújo Oliveira, Débora Marques de Miranda, Ana Cristina Simões E Silva
BACKGROUND: The aim of this cross-sectional study was to investigate inflammatory biomarkers in urine samples of 24 fetuses with posterior urethral valve (PUV) collected at 22 ± 4 weeks of gestation and to compare the findings with measurements in urine samples of 22 male healthy preterm neonates at 23 ± 4 weeks (control group). METHODS: Inflammatory biomarkers in urine were measured using a cytometric bead array [interleukin (IL)-2, IL-4, IL-6, IL-10, interferon (IFN)-γ, soluable tumor necrosis factor receptor (TNFR) 1, sTNFR2, monocyte chemoattractant protein-1/chemokine ligand 2 (MCP-1/CCL2), eotaxin/CCL11 and interferon gamma-induced protein/10/C-X-C motif chemokine 10 (IP-10/CXCL10)] and ELISA assays [TNF, IL-8/CXCL8 and transforming growth factor-beta (TGF-β)]...
February 22, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28209393/commentary-on-cystometrogram-appearance-in-puv-is-reliably-quantified-by-the-swrd-score-and-presages-the-need-for-intervention
#2
Michael Mitchell
No abstract text is available yet for this article.
February 1, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28159527/cystometrogram-appearance-in-puv-is-reliably-quantified-by-the-shape-wall-reflux-and-diverticuli-swrd-score-and-presages-the-need-for-intervention
#3
A Niyogi, K Lumpkins, A Robb, L McCarthy
OBJECTIVE: Radiological bladder abnormalities in boys with posterior urethral valves (PUV) are well recognised; however, the assessment is subjective. The shape, wall, reflux and diverticuli (SWRD) score objectively assesses shape, wall, reflux and diverticuli in a simple way. This study was undertaken to demonstrate that the SWRD score is reliable, reproducible and correlates with bladder outcome and videourodynamic (VUD) assessment in boys with PUV. MATERIALS AND METHODS: Three blinded assessors determined the SWRD scores of PUV bladders from cystometrograms taken during VUD from September 2012 to October 2013...
January 12, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28072617/evaluation-of-the-response-to-breast-cancer-neoadjuvant-chemotherapy-using-18f-fdg-positron-emission-mammography-compared-with-whole-body-18f-fdg-pet-a-prospective-observational-study
#4
Mutsumi Noritake, Kazutaka Narui, Tomohiro Kaneta, Sadatoshi Sugae, Kentaro Sakamaki, Tomio Inoue, Takashi Ishikawa
PURPOSE: The aim of this study was to assess therapeutic response to breast cancer neoadjuvant chemotherapy (NAC) by F-FDG positron emission mammography (PEM) compared with that to whole-body F-FDG PET (WBPET). METHODS: Twenty patients underwent WBPET and PEM 3 times: the first time was before NAC, the second time was after 2 courses of NAC, and the third time was after all courses of NAC. A pathological complete response (pCR) was defined as no evidence of residual invasive cancer with or without ductal carcinoma in situ...
March 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28065374/predictive-value-of-ct-for-first-esophageal-variceal-bleeding-in-patients-with-cirrhosis-value-of-para-umbilical-vein-patency
#5
Paul Calame, Maxime Ronot, Sébastien Bouveresse, Jean-Paul Cervoni, Valérie Vilgrain, Éric Delabrousse
PURPOSE: To evaluate if the presence/size of a para-umbilical vein (PUV) on computed tomography (CT) are associated with a first esophageal variceal hemorrhage (EVH) in patients with cirrhosis and whether imaging features can help identify patients at increased risk of EVH. MATERIALS AND METHODS: From January 2010 to June 2012 patients with cirrhosis who underwent CT and upper gastrointestinal endoscopy within six months were included. The presence/size of PUV was noted...
February 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28031548/outcome-of-antenatally-presenting-posterior-urethral-valves-puv-in-children
#6
T P Joseph, V K Gopi, P R Babu, K V Satish Kumar
OBJECTIVE: To analyse the outcome of children with posterior urethral valves who presented with antenatal hydronephrosis. METHODS: A 10-year retrospective review of records of 70 children with posterior, urethral volves. RESULTS: The mean (SD) gestational age at diagnosis was 34 (4.48) weeks and age at intervention was 130.5 (170.9) days. The nadir creatinine was significantly raised (>1.2mg/dl) in children with oligohydramnios and diversion...
December 5, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/28009141/operative-cystoscopy-in-the-neonatal-period
#7
Salvatore Arena, Tiziana Russo, Patrizia Perrone, Carmelo Romeo
Aim of the study is to report the experience in the last three years about endourological treatment of newborns affected by genito- and urinary malformation, implying critical urinary tract dilatation and bladder mass requiring a neonatal operative management. Seven - four males and three female - patients were treated cystoscopically during the neonatal period. Three newborns with a posterior urethral valves (PUV), underwent a successful ablation of PUV. In a male with infected persistent large mullerian duct and subsequent acute urinary retention, a cystoscopically-assisted catheterization was performed...
December 20, 2016: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
https://www.readbyqxmd.com/read/27889869/left-ventricular-speckle-tracking-derived-cardiac-strain-and-cardiac-twist-mechanics-in-athletes-a-systematic-review-and-meta-analysis-of-controlled-studies
#8
REVIEW
Alexander Beaumont, Fergal Grace, Joanna Richards, John Hough, David Oxborough, Nicholas Sculthorpe
BACKGROUND: The athlete's heart is associated with physiological remodeling as a consequence of repetitive cardiac loading. The effect of exercise training on left ventricular (LV) cardiac strain and twist mechanics are equivocal, and no meta-analysis has been conducted to date. OBJECTIVE: The objective of this systematic review and meta-analysis was to review the literature pertaining to the effect of different forms of athletic training on cardiac strain and twist mechanics and determine the influence of traditional and contemporary sporting classifications on cardiac strain and twist mechanics...
November 26, 2016: Sports Medicine
https://www.readbyqxmd.com/read/27749038/bifurcation-in-the-ultrafast-dynamics-of-the-photoactive-yellow-proteins-from-leptospira-biflexa-and-halorhodospira-halophila
#9
L Tyler Mix, Julia Kirpich, Masato Kumauchi, Jie Ren, Mikas Vengris, Wouter D Hoff, Delmar S Larsen
We explored the photoisomerization mechanisms in novel homologues of photoactive yellow protein (PYP) from Leptospira biflexa (Lbif) to identify conserved features and functional diversity in the primary photochemistry of this family of photoreceptors. In close agreement with the prototypical PYP from Halorhodospira halophila (Hhal), we observe excited-state absorbance near 375 nm and stimulated emission near 500 nm, with triphasic excited-state decay. While the excited-state decay for Lbif PYP is the slowest among those of known PYPs due to the redistribution of the amplitudes of the three decay components, the quantum yield for productive photocycle entry is very similar to that of Hhal PYP...
November 8, 2016: Biochemistry
https://www.readbyqxmd.com/read/27720773/long-term-impacts-of-concurrent-posterior-urethral-valve-ablation-and-bladder-neck-incision-on-urinary-continence-and-ejaculation
#10
Sorena Keihani, Abdol-Mohammad Kajbafzadeh, Seyedeh Maryam Kameli, Reza Abbasioun
OBJECTIVE: To assess the long-term impacts of bladder neck incision (BNI) on continence and ejaculatory function of adults who underwent concurrent posterior urethral valve (PUV) ablation and BNI during childhood. MATERIALS AND METHODS: A retrospective chart review was performed to find all adult patients with relevant history. All patients had undergone BNI at 6 o'clock proximal to the verumontanum with caution to leave the adventitia and verumontanum untouched...
January 2017: Urology
https://www.readbyqxmd.com/read/27684547/parents-perceptions-of-counselling-following-prenatal-diagnosis-of-congenital-anomalies-of-the-kidney-and-urinary-tract-a-qualitative-study
#11
Sarah Marokakis, Nadine A Kasparian, Sean E Kennedy
OBJECTIVES: To explore parents' experiences of counselling after prenatal diagnosis of congenital anomalies of the kidney and urinary tract. SUBJECTS AND METHODS: Parents of a child born between September 2012 and March 2015 with posterior urethral valves (PUV) or multicystic dysplastic kidney (MCDK) completed a semi-structured telephone interview, demographic survey, and the 21-item self-report Depression, Anxiety and Stress Scales questionnaire. Qualitative data were analysed thematically using NVivo10 software...
September 29, 2016: BJU International
https://www.readbyqxmd.com/read/27680794/c3-cardiovascular-changes-from-pre-pregnancy-to-early-pregnancy-in-relation-to-viability-of-pregnancy
#12
Lin Foo, Carmel McEniery, Ian Wilkinson, Christoph Lees
INTRODUCTION: Inadequate cardiovascular adaptation to pregnancy has been postulated as a potential cause or consequence of early pregnancy loss. We sought to investigate pre- and early pregnancy cardiovascular function in women with a viable pregnancy beyond the first trimester, and those suffering a first trimester pregnancy loss. METHODS: We recruited healthy women trying for pregnancy without assisted reproductive technology into an observational pre-conception study, and recorded pregnancy loss as a clinical endpoint...
August 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27570093/fetal-bladder-outlet-obstruction-embryopathology-in-utero-intervention-and-outcome
#13
REVIEW
Marie-Klaire Farrugia
Fetal bladder outlet obstruction (BOO), most commonly caused by posterior urethral valves (PUV), remains a challenging and multi-faceted condition. Evolving techniques, and refinement in ultrasound, optics and instrumentation, have increased our rate of prenatal diagnosis, and enabled valve ablation not only in smaller newborns, but also in fetuses. Long-term outcome studies have raised our awareness of the silent damage caused by bladder dysfunction and polyuria and encouraged their proactive management. In spite of our best efforts, the proportion of boys with PUV who progress to chronic and end-stage renal disease (ESRD) has not changed in the last 25 years...
October 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27504374/spectrum-of-renal-and-urinary-tract-diseases-in-kashmiri-children
#14
Mohd Ashraf, Virender Kumar, Rifat Ara Bano, Khursheed Ahmed Wani, Javed Ahmed, Kaisar Ahmed
INTRODUCTION: Definite paucity of data pertaining to spectrum of renal and urinary tract diseases in our state and in various parts of India forms the basis of this study. Available data has emphasized more on specific clinical syndromes and chronic renal diseases rather than over all spectrums of renal and urinary tract diseases, that too in adult population. AIM: The present study a retrospective analysis, forms one of the basic data of paediatric nephrology and urology related disorders in our state...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27484256/anxiety-associated-with-diagnostic-uncertainties-in-early-pregnancy
#15
A Richardson, N Raine-Fenning, S Deb, B Campbell, K Vedhara
OBJECTIVES: To determine anxiety levels of women presenting to Early Pregnancy Assessment Units (EPAU) with abdominal pain and/or vaginal bleeding and assess how these change over time and according to ultrasonographic diagnosis. METHODS: We undertook a prospective cohort study in a EPAU in a large UK teaching hospital. Women with abdominal pain and/or vaginal bleeding in early pregnancy (less than 12 weeks gestation) presenting for the first time were eligible for inclusion in the study...
August 3, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27374758/posterior-urethral-valves-and-vesicoureteral-reflux-can-prenatal-ultrasonography-distinguish-between-these-two-conditions-in-male-fetuses
#16
Yvon Chitrit, Mathilde Bourdon, Diane Korb, Christine Grapin-Dagorno, Félicia Joinau-Zoulovits, Edith Vuillard, Annabel Paye-Jaouen, Matthieu Peycelon, Nadia Belarbi, Anne-Lyse Delezoide, Thomas Schmitz, Alaa El Ghoneimi, Olivier Sibony, Jean-François Oury
OBJECTIVE: The objective of the study was to evaluate prenatal sonographic signs that distinguish male fetuses with posterior urethral valves (PUV) from those with vesicoureteral reflux (VUR). METHODS: Prenatal data were retrospectively retrieved from all consecutive women delivering between 2003 and 2012 of a male newborn with a postnatal diagnosis of PUV or VUR. Prenatal parameters included fetal bladder characteristics, identification of a dilated posterior urethra, and change in shape and size in the fetal renal pelvis or ureter...
September 2016: Prenatal Diagnosis
https://www.readbyqxmd.com/read/27350093/detection-fate-and-inactivation-of-pathogenic-norovirus-employing-settlement-and-uv-treatment-in-wastewater-treatment-facilities
#17
M Barrett, K Fitzhenry, V O'Flaherty, W Dore, S Keaveney, M Cormican, N Rowan, E Clifford
It is accepted that discharged wastewaters can be a significant source of pathogenic viruses in receiving water bodies contributing to pollution and may in turn enter the human food chain and pose a risk to human health, thus norovirus (NoV) is often a predominant cause of gastroenteritis globally. Working with NoV poses particular challenges as it cannot be readily identified and detection by molecular methods does not assess infectivity. It has been proposed that the infectivity of NoV may be modelled through the use of an alternative virus; F-specific RNA (FRNA) bacteriophages; GA genotype and other FRNA bacteriophages have been used as a surrogate in studies of NoV inactivation...
October 15, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27344603/posterior-urethra-anterior-urethra-ratio-in-the-evaluation-of-success-following-puv-ablation
#18
R Babu, S Hariharasudhan, C Ramesh
INTRODUCTION: There are conflicting reports on the criteria with which to determine success following posterior urethral valve (PUV) ablation. The aims of this study were to assess the value of the posterior urethra: anterior urethra ratio (PAR) in predicting successful PUV ablation. MATERIALS AND METHODS: All neonates and infants with confirmed PUV on voiding cystourethrogram (VCUG) were included. Initial PAR was computed by dividing maximum posterior urethral diameter by anterior urethral diameter...
December 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27266227/positron-emission-mammography-for-breast-cancer-in-rajavithi-hospital
#19
Araya Boonyaleepan
BACKGROUND: Positron Emission Mammography (PEM) is a new modality in the investigation of breast cancer in Rajavithi Hospital, and its effectiveness has not yet been evaluated. OBJECTIVE: To study the effectiveness and characterization of breast images taken with PEM in Rajavithi Hospital. MATERIAL AND METHOD: This was a retrospective study in which data were collected and analyzed of patients who were investigated by PEM in Rajavithi Hospital between 18 September 2013 and 31 May 2014...
February 2016: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
https://www.readbyqxmd.com/read/27261184/genetic-basis-of-posterior-urethral-valves-inheritance
#20
Cinzia Chiaramonte, Denisia Bommarito, Elisa Zambaiti, Vincenzo Antona, Giuseppe Li Voti
OBJECTIVE: To highlight genetic pattern of posterior urethral valves (PUVs), we performed a genetic study on 2 siblings affected. PUVs are the most common congenital cause of lower urinary tract obstruction and an important cause of renal failure in infants (50% progress to end-stage renal disease in 10 years). PUVs occur in 1 of 5000-8000 male infants, but real incidence is arduous to determine because of the wide spectrum of possible clinical presentation. A different recurrence rate is reported in African Americans and children with Down syndrome, although usually PUVs are not found in syndromic conditions but constitute an isolated disorder...
September 2016: Urology
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