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https://www.readbyqxmd.com/read/29783971/posterior-urethral-valves-10-years-audit-of-epidemiologic-diagnostic-and-therapeutic-aspects-in-yaound%C3%A3-gynaeco-obstetric-and-paediatric-hospital
#1
Faustin Felicien Mouafo Tambo, Paul Nkemtendong Tolefac, Marcelin Ngowe Ngowe, Jacqueline Ze Minkande, Landry Mbouche, Georgette Guemkam, Neville Alemnju Telelen, Fru Fobuzshi Angwafo, Aurelien Maurice Sosso
BACKGROUND: The incidence of posterior urethral valve (PUV) is estimated at 1:5000-1:8000 males. It is the most common paediatric urologic urgency and the most common cause of male obstructive uropathy and chronic renal failure in children. The study aimed to describe the experience of Yaoundé gynaeco-obstetrics and paediatric hospital in the management of PUV. METHODS: Retrospectively, medical records were retrieved over a ten year period and all data recorded and analyzed for study objectives...
May 21, 2018: BMC Urology
https://www.readbyqxmd.com/read/29774481/predicting-and-modifying-risk-for-development-of-renal-failure-in-boys-with-posterior-urethral-valves
#2
REVIEW
Christopher J Long, Diana K Bowen
PURPOSE OF REVIEW: The purpose of this review is to bring the reader up to date on the current risk factors for the development of renal deterioration in the boys with posterior urethral valves (PUV) and approaches to modify this risk. RECENT FINDINGS: Renal bladder ultrasound (RBUS) is routinely performed in boys with PUV and recent advancements allow imaging processing that can more accurately quantify renal parenchyma and correlate this with risk for renal loss...
May 17, 2018: Current Urology Reports
https://www.readbyqxmd.com/read/29673009/in-utero-spontaneous-bladder-rupture-in-a-fetus-with-posterior-urethral-valve-a-case-report-of-prenatal-diagnosis-and-management
#3
Shoichi Magawa, Hiroaki Tanaka, Masafumi Nii, Shintaro Maki, Yuki Kamimoto, Tomoaki Ikeda
Posterior urethral valve (PUV) rarely causes bladder rupture. We experienced hydronephrosis due to ureteral obstruction after the natural repair of a ruptured bladder in a fetus with PUV. Fetal ascites and oligohydramnios were diagnosed at 26 weeks' gestational age. While we followed up with ultrasonography, we regularly removed the fetal ascites via abdominal puncture, injecting warm saline instead of amniotic fluid. At 35 weeks' gestational age, the infant was diagnosed with severe bilateral hydronephrosis, absent of ascites and oligohydramnios...
April 19, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29664229/a-classic-twin-study-of-lower-urinary-tract-obstruction-report-of-3-cases-and-literature-review
#4
Sandra Frese, Alexander Weigert, Bernd Hoppe, Markus Feldkötter, Michael Ludwig, Stefanie Weber, Katarzyna Kiliś-Pstrusińska, Marcin Zaniew, Heiko Reutter, Alina C Hilger
OBJECTIVE: The aim of the present study was to investigate genetic effects in the formation of congenital lower urinary tract obstruction (LUTO) comprising posterior urethral valves (PUV), urethral atresia, and urethras with variable degrees of stenosis. METHODS: A classic twin study was performed by assessing LUTO twin pairs from the literature. Furthermore, data regarding 3 previously unreported twin pairs with PUV from University of Bonn, Essen and Wrocławs own in-house databases were added...
April 17, 2018: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/29496422/bladder-contractility-index-in-posterior-urethral-valve-a-new-marker-for-early-prediction-of-progression-to-renal-failure
#5
M S Ansari, Sandeep Kumar Nunia, Ankur Bansal, Prempal Singh, Virender Sekhon, Dharmveer Singh, Rahul Soni, Priyank Yadav
INTRODUCTION: Posterior urethral valve (PUV) is the most common cause of pediatric end stage renal disease (ESRD), imposing a major health burden on medical community caregivers and adversely affecting the quality of life of patients. Chronic kidney disease (CKD) stage III or estimated GFR of <60 mL/min/1.73 m2 is known to be associated with more adverse renal, cardiovascular, and clinical outcomes. Thus, it is desirable to identify factors predicting the rapid and early progression of disease...
November 22, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29225122/dual-pathology-causing-congenital-bladder-outlet-obstruction
#6
Ruth Kwong, Navroop S Johal, Anand Upasani, Anu Paul, Peter Cuckow
Anterior urethral syringocele is an uncommon congenital deformity characterised by cystic dilatation of bulbo-urethral gland ducts and is usually asymptomatic. We present a case on 4-day-old male neonate who presented with bilateral antenatal hydroureteronephrosis and renal impairment and found to have urethral syringocele and posterior urethral valves (PUV).
December 7, 2017: Urology
https://www.readbyqxmd.com/read/29223674/prediction-of-need-for-intervention-in-posterior-urethral-valves-use-of-urine-osmolality
#7
Anna E Wright, Ruth Wragg, Joana Lopes, Andrew Robb, Liam McCarthy
AIM: Renal tubular dysfunction (RTD) causing obligate production of hypoosmolar urine in boys with posterior urethral valves (PUVs) has been described. It is not known how clinically significant this is. We hypothesize that a feedback loop is present in many PUV boys who suffer deterioration of their lower urinary tract (LUT). RTD results in hypoosmolar urine, obligate polyuria, and bladder stretch-injury. The increasing back-pressure worsens RTD, thus exacerbating the injury. Coexisting renal dysplasia and acquired renal scarring exacerbate this...
February 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29202392/serial-hcg-and-progesterone-levels-to-predict-early-pregnancy-outcomes-in-pregnancies-of-uncertain-viability-a-prospective-study
#8
Claire Puget, Yolaine Joueidi, Estelle Bauville, Bruno Laviolle, Claude Bendavid, Vincent Lavoué, Maela Le Lous
OBJECTIVE: To assess the value of serial hCG and progesterone serum level in the diagnosis of early pregnancy viability. METHODS: It was a prospective cohort study. Women with a pregnancy of uncertain viability (PUV), defined as the presence of an intra-uterine embryo with a crown-rump length <7mm with no cardiac activity or an intra-uterine gestational sac size <25mm with no visible embryonic structure in a transvaginal ultrasound scan (TVS) were eligible...
January 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29202099/predictors-and-consequences-of-rural-clients-satisfaction-level-in-the-district-public-private-mixed-health-system-of-bangladesh
#9
Ashim Roy, Trudy van der Weijden, Nanne de Vries
Background: We investigated predictors of the rural clients' satisfaction level (CSL), and interlinks between perceived specific service quality (PSSQ), perceived utility value (PUV), CSL, and clients' reactions (CR) towards current and future utilization of providers and facilities in the public-private mixed health system of Bangladesh. Methods: A quantitative study using interviewer-administered questionnaire was conducted among 400 rural patients. CSL was measured both directly and indirectly...
2017: Global Health Research and Policy
https://www.readbyqxmd.com/read/29159472/current-strategies-to-predict-and-manage-sequelae-of-posterior-urethral-valves-in-children
#10
Aniruddh V Deshpande
Posterior urethral valves (PUV) constitute a significant urological cause of chronic kidney disease (CKD) in children. The condition is characterised by the unique pathophysiology of the evolution of bladder dysfunction after relief of obstruction, which contributes to CKD. Improvements in prenatal diagnosis followed by selective foetal intervention have not yet produced improvement in long-term renal outcomes, although better patient selection may alter this in the future. Proactive management with surveillance, pharmacotherapy, timed voiding, double voiding, and/or assisted bladder-emptying, is being increasingly offered to those with severe bladder dysfunction and has the potential of reducing the burden of renal disease...
November 20, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29110519/caring-for-infants-with-posterior-urethral-valves-a-qualitative-study-of-parents-experiences
#11
Sarah Marokakis, Nadine A Kasparian, Sean E Kennedy
This study aimed to explore the perspectives and experiences of parents caring for an infant with posterior urethral valves (PUVs). Eight parents participated in a semi-structured, individual telephone interview, with qualitative data collected and analysed thematically using NVivo11 software. Two main themes emerged as interconnecting aspects of parents' experiences: (1) trying to face the challenges and (2) learning to cope. Parents felt challenged by the need to attend to their child's medical care, while developing a bond with their baby, trying to maintain positivity for their child's future and managing the impact of the condition on their family...
January 1, 2017: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://www.readbyqxmd.com/read/29072547/serum-concentrations-of-ang-2-and-flt-1-may-be-predictive-of-pregnancy-outcome-in-women-with-pregnancies-of-uncertain-viability-a-phase-i-exploratory-prognostic-factor-study
#12
Alison Richardson, Shilpa Deb, Bruce Campbell, Nick Raine-Fenning
The aim of this study was to determine whether serum concentrations of Ang-1, Ang-2, Flt-1, IL-15 and/or TRAIL can be used to predict outcome in women with pregnancies of uncertain viability (PUVs). Women presenting to the Early Pregnancy Unit at the Queen's Medical Centre in Nottingham between 17.06.14 and 01.09.15 were prospectively recruited. Serum concentrations of Ang-1, Ang-2, Flt-1, IL-15 and TRAIL were measured in women with PUVs. Women were followed-up according to departmental protocols until viability was determined...
April 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29071146/posterior-urethral-valves-impact-of-low-birth-weight-and-preterm-delivery-on-the-final-renal-outcome
#13
Osama M Sarhan
OBJECTIVE: To investigate the relationship between low birth weight (LBW; <2.5 kg) and preterm delivery (<37 weeks gestational age) and final renal outcome in infants with posterior urethral valves (PUVs), emphasising the risk factors for the development of chronic kidney disease (CKD). PATIENTS AND METHODS: A retrospective review was performed for all infants with PUVs who were treated between 1990 and 2010. In all, 52 infants were identified to have LBW and/or delivered preterm (Group 1)...
June 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29061539/impact-of-adjuvant-urinary-diversion-versus-valve-ablation-alone-on-progression-from-chronic-to-end-stage-renal-disease-in-posterior-urethral-valves-a-single-institution-15-year-time-to-event-analysis
#14
Michael E Chua, Jessica M Ming, Simon Carter, Yaser El Hout, Martin A Koyle, Damien Noone, Walid A Farhat, Armando J Lorenzo, Darius J Bägli
PURPOSE: Long-term progression to end stage renal disease of valve ablation alone vs ablation followed by additional urinary diversion were compared among children with stage 3 chronic kidney disease due to posterior urethral valves. MATERIALS AND METHODS: We performed a retrospective study of children with posterior urethral valves and stage 3 chronic kidney disease treated at a single institution between 1986 and 2011. The 3 treatment groups were classified as group 1-valve ablation alone, group 2-ablation plus subsequent vesicostomy and group 3-ablation followed by ureterostomies and/or pyelostomies...
October 20, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28712168/justification-for-re-look-cystoscopy-after-posterior-urethral-valve-fulguration
#15
Gul Nawaz, Ijaz Hussain, Shujah Muhammad, Muhammad Imran Jamil, Asad Ur Rehman, Nadeem Iqbal, Saeed Akhter
BACKGROUND: Posterior urethral valve (PUV) is life-threatening congenital anomaly of the urinary tract that results in vesicoureteric reflux, recurrent UTI, voiding dysfunction and renal insufficiency if not treat timely. Endoscopic ablation of posterior urethral valves using cold knife or laser is the current gold standard therapy. Many urologists go for repeat cystoscopy to see residual valve or stricture while others repeat VCUG to measure the posterior to anterior urethral ratio for residual obstruction...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28666918/urinary-tract-infection-after-retrograde-urethrogram-in-children-a-multicenter-study
#16
Neha R Malhotra, Jared R Green, Cynthia K Rigsby, Jane L Holl, Earl Y Cheng, Emilie K Johnson
INTRODUCTION: The risk of post-procedural urinary tract infection (ppUTI) after retrograde urethrogram (RUG) has not been well quantified. Prophylactic antibiotics may reduce the risk, but must be weighed against the risks of antibiotic resistance. Prior research has shown that this risk is variable after voiding cystourethrogram (0-42% reported ppUTI rate) and appears to be low after urodynamics (0-4.8%) but this risk has not been well documented for patients undergoing RUG. OBJECTIVE: We aimed to (1) describe the rate of ppUTI after RUG, and (2) examine factors associated with use of antibiotics at the time of RUG...
December 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28638819/testosterone-modifies-alterations-to-detrusor-muscle-after-partial-bladder-outlet-obstruction-in-juvenile-mice
#17
Andrew S Flum, Paula R Firmiss, Diana K Bowen, Natalie Kukulka, Grace B Delos Santos, Robert W Dettman, Edward M Gong
Lower urinary tract symptoms secondary to posterior urethral valves (PUV) arise in boys during adolescence. The reasons for this have previously been attributed to increased urine output as boys experience increased growth. Additionally, there are few choices for clinicians to effectively treat these complications. We formed the new hypothesis that increased androgen levels at this time of childhood development could play a role at the cellular level in obstructed bladders. To test this hypothesis, we investigated the role of testosterone on bladder detrusor muscle following injury from partial bladder outlet obstruction (PO) in mice...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28612060/aggressive-diagnosis-and-treatment-for-posterior-urethral-valve-as-an-etiology-for-vesicoureteral-reflux-or-urge-incontinence-in-children
#18
REVIEW
Hideo Nakai, Taiju Hyuga, Shina Kawai, Taro Kubo, Shigeru Nakamura
Vesicoureteral reflux (VUR) is one of the most common diseases in pediatric urology and classified into primary and secondary VUR. Although posterior urethral valve (PUV) is well known as a cause of the secondary VUR, it is controversial that minor urethral deformity recognized in voiding cystourethrography represents mild end of PUV spectrum and contributes to the secondary VUR. We have been studying for these ten years congenital urethral obstructive lesions with special attention to its urethrographic and endoscopic morphology as well as therapeutic response with transurethral incision...
June 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28495235/prenatal-detection-of-megacystis-not-always-an-adverse-prognostic-factor-experience-in-25-consecutive-cases-in-a-tertiary-referral-center-with-complete-neonatal-outcome-and-follow-up
#19
Marcella Pellegrino, Daniela Visconti, Vincenzo Davide Catania, Luisa D'Oria, Carlo Manzoni, Maria Giovanna Grella, Alessandro Caruso, Lucia Masini, Giuseppe Noia
INTRODUCTION: Megacystis is a condition of abnormal enlarged fetal bladder for gestational age, which is usually associated with urological malformations that may constitute a life-threatening condition for the baby. OBJECTIVE: The purpose of this study was to assess the prognostic and etiological criteria of fetal megacystis and to describe the neonatal outcome in a large series collected in a single tertiary center. STUDY DESIGN: A retrospective observational study was conducted between 2008 and 2012...
October 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28464563/shear-and-extensional-rheology-of-commercial-thickeners-used-for-dysphagia-management
#20
Muhammad Qazi Waqas, Johan Wiklund, Annika Altskär, Olle Ekberg, Mats Stading
People who suffer from swallowing disorders, commonly referred to as dysphagia, are often restricted to a texture-modified diet. In such a diet, the texture of the fluid is modified mainly by the addition of gum or starch-based thickeners. For optimal modification of the texture, tunable rheological parameters are shear viscosity, yield stress, and elasticity. In this work, the flow properties of commercial thickeners obtained from major commercial suppliers were measured both in shear and extensional flow using a laboratory viscometer and a newly developed tube viscometry technique, termed Pulsed Ultrasound Velocimetry plus Pressure Drop (PUV + PD)...
December 2017: Journal of Texture Studies
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