Philosophy of science

BACKGROUND: This study compares emergency department (ED) revisits for patients receiving hospital-based substance-use support compared to those who did not receive specialized addiction services at Health Sciences North in Sudbury, Ontario, Canada. METHODS: The study is a retrospective observational study using administrative data from all patients presenting with substance use disorder (SUD) at Health Sciences North from January 1, 2018, and August 31, 2022 with ICD-10 codes from the Discharge Abstract Database (DAD) and the National Ambulatory Care Database (NACRS)...

Contemporary mind and brain sciences provide theories and data that seem to confirm a hypothesis about human nature that we might formulate as follows. Human life is conditioned by a need that is no less important than elementary biological needs (such as survival and reproduction) or universal forms of social competition: the need to build and, indeed, defend a subjective identity whose solidity and clarity are the foundation of our intra- and inter-personal equilibrium and therefore of psychological well-being and mental health...

In line with recent proposals for experimental philosophy and philosophy of science in practice, we propose that the philosophy of medicine could benefit from incorporating empirical research, just as bioethics has. In this paper, we therefore take first steps towards the development of an empirical philosophy of medicine, that includes investigating practical and moral dimensions. This qualitative study gives insight into the views and experiences of a group of various medical professionals and patient representatives regarding the conceptualization of health and disease concepts in practice and the possible problems that surround them...

OBJECTIVES: Pediatric Hematopoietic Stem Cell Transplant (HSCT) profoundly impacts the physical, psychological, and social aspects of parents' lives. Thus, this study aimed to explore the experiences of parents living with a child with cancer who undergoes HSCT. METHODS: This qualitative study involved 20 parents of children with cancer who were undergoing HSCT at a referral hospital in Iran. Purposive sampling was used to select the participants from February 2023 to November 2023...

Observational and experimental discoveries of new factual entities such as objects, systems, or processes, are major contributors to some advances in the life sciences. Yet, whereas discovery of theories was extensively deliberated by philosophers of science, very little philosophical attention was paid to the discovery of factual entities. This paper examines historical and philosophical aspects of the experimental discovery by Carl Woese of archaea, prokaryotes that comprise one of the three principal domains of the phylogenetic tree...

Kuhnian philosophy of science implies that progress in the study of open-ended evolution (OEE) would be accelerated if the OEE science community were to agree on some examples of striking success in OEE science. This article recounts the important role of scientific paradigms and scientific exemplars in creating the productivity of what Kuhn, in The Structure of Scientific Revolutions, calls "normal" science, and it describes how the study of OEE today would benefit from exhibiting more of the hallmarks of normal science...

I argue that the question of animal consciousness is an extrapolation problem and, as such, is best tackled by deploying currently accepted methodology for validating experimental models of a phenomenon of interest. This methodology relies on an assessment of similarities and dissimilarities between experimental models, the partial replication of findings across complementary models, and evidence from the successes and failures of explanations, technologies and medical applications developed by extrapolating and aggregating findings from multiple models...

BACKGROUND: The Health Promoting Universities (HPU) concept is undertheorized, with no African university belonging to the International Network of Health Promoting Universities (IHPU). AIM: The study aimed to investigate the status of the HPU concept globally to inform emerging HPUs, more specifically in Africa, regarding its implementation. METHODS: An integrative literature review of studies conducted between 1 January 2013 and 5 November 2023 was conducted from online databases (PubMed, Scopus, Web of Science, Lilacs, CINAHL and Medline)...

No abstract text is available yet for this article.

The early history of string theory is marked by a shift from strong interaction physics to quantum gravity. The first string models and associated theoretical framework were formulated in the late 1960s and early 1970s in the context of the S-matrix program for the strong interactions. In the mid-1970s, the models were reinterpreted as a potential theory unifying the four fundamental forces. This paper provides a historical analysis of how string theory was developed out of S-matrix physics, aiming to clarify how modern string theory, as a theory detached from experimental data, grew out of an S-matrix program that was strongly dependent upon observable quantities...

The rapid growth of cultural evolutionary science, its expansion into numerous fields, its use of diverse methods, and several conceptual problems have outpaced corollary developments in theory and philosophy of science. This has led to concern, exemplified in results from a recent survey conducted with members of the Cultural Evolution Society, that the field lacks 'knowledge synthesis', is poorly supported by 'theory', has an ambiguous relation to biological evolution and uses key terms (e.g. 'culture', 'social learning', 'cumulative culture') in ways that hamper operationalization in models, experiments and field studies...

Glycosylphosphatidylinositol-anchored proteins (GPI-APs) are anchored at the outer phospholipid layer of eukaryotic plasma membranes exclusively by a glycolipid. GPI-APs are not only released into extracellular compartments by lipolytic cleavage. In addition, certain GPI-APs with the glycosylphosphatidylinositol anchor including their fatty acids remaining coupled to the carboxy-terminus of their protein components are also detectable in body fluids, in response to certain stimuli, such as oxidative stress, radicals or high-fat diet...

In this paper I discuss the first "multi-messenger" observations of a binary neutron star merger and kilonova. These observations, touted as "revolutionary," included both gravitational-wave and electromagnetic observations of a single source. I draw on analogies between astrophysics and historical sciences (e.g., paleontology) to explain the significance of this for (gravitational-wave) astrophysics. In particular, I argue that having independent lines of evidence about a target system enables the use of argumentative strategies-the "Sherlock Holmes" method and consilience-that help overcome the key challenges astrophysics faces as an observational and historical science...

Doubtlessly, kidney patients present a common challenge in endodontic practice, so specialists in this field should know and follow several key points regarding this group of medically compromised patients. This review paper aims to explain kidney disease and its complications, as well as notify and discuss the latest concepts on anesthesia, pain management, antibiotic prophylaxis/stewardship, and the risk of viral diseases for these patients, and also the oral manifestations of kidney diseases that may guide endodontists to diagnose kidney intervention and prevent hazardous consequences that may happen during or following endodontic practice on these patients...

Optimization is about finding the best available object with respect to an objective function. Mathematics and quantitative sciences have been highly successful in formulating problems as optimization problems, and constructing clever processes that find optimal objects from sets of objects. As computers have become readily available to most people, optimization and optimized processes play a very broad role in societies. It is not obvious, however, that the optimization processes that work for mathematics and abstract objects should be readily applied to complex and open social systems...

Algebraic quantum field theory (AQFT) puts forward three "causal axioms" that aim to characterize the theory as one that implements relativistic causation: the spectrum condition, microcausality, and primitive causality. In this paper, I aim to show, in a minimally technical way, that none of them fully explains the notion of causation appropriate for AQFT because they only capture some of the desiderata for relativistic causation I state or because it is often unclear how each axiom implements its respective desideratum...

The idea that the dynamical properties of quantum systems are invariably relative to other systems has recently regained currency. Using Relational Quantum Mechanics (RQM) for a case study, this paper calls attention to a question that has been underappreciated in the debate about quantum relativism: the question of whether relativity iterates. Are there absolute facts about the properties one system possesses relative to a specified reference, or is this again a relative matter, and so on? It is argued that RQM (in its best-known form) is committed to what I call the Unrestricted Iteration Principle (UIP), and thus to an infinite regress of relativisations...

We are each aware of our own experiences as they occur, but in this inner awareness our experiences do not seem to be presented to us as objects in the way that they typically are when we reflect on them. A number of philosophers, principally in the phenomenological tradition, have characterised this in terms of inner awareness being a non-objectifying mode of awareness. This claim has faced persistent objections that the notion of non-objectifying awareness is obscure or merely negatively characterised. In this paper I shall outline a positive conception of a non-objectifying mode of awareness, feature-encountering awareness...

The neuroscience of consciousness is undergoing a significant empirical acceleration thanks to several adversarial collaborations that intend to test different predictions of rival theories of consciousness. In this context, it is important to pair consciousness science with confirmation theory, the philosophical discipline that explores the interaction between evidence and hypotheses, in order to understand how exactly, and to what extent, specific experiments are challenging or validating theories of consciousness...

In the United States, there is little clarity on the qualifications and availability of equine nutritionists. Currently, no regulatory body exists for formal credentialing outside of veterinary medicine. Most equine nutritionists are not veterinarians but do have advanced scientific degrees (Master of Science and/or Doctor of Philosophy) in the field of Animal Science. However, not all reporting to be equine nutritionists have formal education in the field of equine nutrition. To discuss this, a workshop was held at the 2023 Equine Science Society (ESS) meeting...