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https://www.readbyqxmd.com/read/28933882/maternal-depressive-symptoms-mother-child-interactions-and-children-s-executive-function
#1
Noa Gueron-Sela, Marie Camerota, Michael T Willoughby, Lynne Vernon-Feagans, Martha J Cox
This study examined the independent and mediated associations between maternal depression symptoms (MDS), mother-child interaction, and child executive function (EF) in a prospective longitudinal sample of 1,037 children (50% boys) from predominantly low-income and rural communities. When children were 6, 15 and 24 months of age, mothers reported their level of depressive symptomatology. At 24 and 36 months of age, mother-child interactions during play were rated for warmth-sensitivity and harsh-intrusiveness, and dyadic joint attention and maternal language complexity were assessed from a book sharing activity...
September 21, 2017: Developmental Psychology
https://www.readbyqxmd.com/read/28927307/biological-therapy-for-non-obstructive-azoospermia
#2
Sarah C Vij, Edmund Sabanegh, Ashok Agarwal
Most male patients with non-obstructive azoospermia (NOA) have no therapeutic options outside of assisted reproductive techniques to conceive a biological child. If mature sperm cannot be obtained from the testes, these patients must rely on options of donor sperm or adoption. Several techniques are in the experimental stage to provide this patient population alternatives for conceiving. Areas covered: This review discusses three of the experimental techniques for restoring fertility in men with NOA: spermatogonial stem cell transplantation, the use of adult and embryonic stem cells to develop mature gametes and gene therapy...
September 19, 2017: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/28923533/subjective-memory-complaints-are-associated-with-brain-activation-supporting-successful-memory-encoding
#3
Jessica M Hayes, Lingfei Tang, Raymond P Viviano, Sanneke van Rooden, Noa Ofen, Jessica S Damoiseaux
Subjective memory complaints, the perceived decline in cognitive abilities in the absence of clinical deficits, may precede Alzheimer's disease. Individuals with subjective memory complaints show differential brain activation during memory encoding; however, whether such differences contribute to successful memory formation remains unclear. Here, we investigated how subsequent memory effects, activation which is greater for hits than misses during an encoding task, differed between healthy older adults aged 50 to 85 years with (n = 23) and without (n = 41) memory complaints...
August 24, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28911135/is-it-me-or-my-hormones-neuroendocrine-activation-profiles-to-visual-food-stimuli-across-the-menstrual-cycle
#4
Yardena Arnoni-Bauer, Atira Bick, Noa Raz, Tal Imbar, Shoshana Amos, Orly Agmon, Limor Marko, Netta Levin, Ram Weiss
Context: Homeostatic energy balance is controlled via the hypothalamus, whereas regions controlling reward and cognitive decision-making are critical for hedonic eating. Eating varies across the menstrual cycle peaking at the midluteal phase. Objective: To test responses of females with regular cycles during midfollicular and midluteal phase and of users of monophasic oral contraception pills (OCPs) to visual food cues. Design: Participants performed a functional magnetic resonance imaging while exposed to visual food cues in four time points: fasting and fed conditions in midfollicular and midluteal phases...
September 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28904907/microdissection-testicular-sperm-extraction
#5
REVIEW
Ryan Flannigan, Phil V Bach, Peter N Schlegel
Microdissection testicular sperm extraction (microTESE) is considered the gold standard method for surgical sperm retrieval among patients with non-obstructive azoospermia (NOA). In this review, we will discuss the optimal evaluation of NOA patients and strategies to medically optimize NOA patients prior to microTESE. In addition, we will also discuss technical principles and pearls to maximize the chances of successful sperm retrieval, sperm retrieval rates (SRR) based upon testicular histology, predictors of successful sperm retrieval, gonadal recovery following microTESE, and potential complications...
August 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28903663/the-shadows-of-the-past-effects-of-historical-group-trauma-on-current-intergroup-conflicts
#6
Noa Schori-Eyal, Yechiel Klar, Sonia Roccas, Andrew McNeill
We examined associations between two orientations based on historical group trauma, a form of enduring group victimhood (Perpetual Ingroup Victimhood Orientation [PIVO]) and the belief that one's group might itself become a victimizer (Fear of Victimizing [FOV]), and attitudes, cognitions, and emotions related to intergroup conflicts. PIVO was positively and FOV was negatively related to aggressive attitudes and emotions toward the outgroup (Studies 1a-1c, Israeli-Palestinian conflict), and to the attribution of responsibility for a series of hostilities to the outgroup (Study 3, Israeli-Palestinian conflict)...
April 2017: Personality & Social Psychology Bulletin
https://www.readbyqxmd.com/read/28900633/clinical-outcomes-in-patients-with-node-negative-breast-cancer-treated-based-on-the-recurrence-score-results-evidence-from-a-large-prospectively-designed-registry
#7
Salomon M Stemmer, Mariana Steiner, Shulamith Rizel, Lior Soussan-Gutman, Noa Ben-Baruch, Avital Bareket-Samish, David B Geffen, Bella Nisenbaum, Kevin Isaacs, Georgeta Fried, Ora Rosengarten, Beatrice Uziely, Christer Svedman, Debbie McCullough, Tara Maddala, Shmuel H Klang, Jamal Zidan, Larisa Ryvo, Bella Kaufman, Ella Evron, Natalya Karminsky, Hadassah Goldberg, Steven Shak, Nicky Liebermann
The 21-gene Recurrence Score® (RS) assay is a validated prognostic/predictive tool in ER + early-stage breast cancer. However, clinical outcome data from prospective studies in RS ≥ 11 patients are lacking, as are relevant real-life clinical practice data. In this retrospective analysis of a prospectively designed registry, we evaluated treatments/clinical outcomes in patients undergoing RS-testing through Clalit Health Services. The analysis included N0 ER + HER2-negative breast cancer patients who were RS-tested from 1/2006 through 12/2010...
2017: NPJ Breast Cancer
https://www.readbyqxmd.com/read/28900632/clinical-outcomes-in-er-her2-node-positive-breast-cancer-patients-who-were-treated-according-to-the-recurrence-score-results-evidence-from-a-large-prospectively-designed-registry
#8
Salomon M Stemmer, Mariana Steiner, Shulamith Rizel, David B Geffen, Bella Nisenbaum, Tamar Peretz, Lior Soussan-Gutman, Avital Bareket-Samish, Kevin Isaacs, Ora Rosengarten, Georgeta Fried, Debbie McCullough, Christer Svedman, Steven Shak, Nicky Liebermann, Noa Ben-Baruch
The Recurrence Score® is increasingly used in node-positive ER+ HER2-negative breast cancer. This retrospective analysis of a prospectively designed registry evaluated treatments/outcomes in node-positive breast cancer patients who were Recurrence Score-tested through Clalit Health Services from 1/2006 through 12/2011 (N = 709). Medical records were reviewed to verify treatments/recurrences/survival. Median follow-up, 5.9 years; median age, 62 years; 53.9% grade 2; 69.8% tumors ≤ 2 cm; 84.5% invasive ductal carcinoma; 42...
2017: NPJ Breast Cancer
https://www.readbyqxmd.com/read/28900478/esophageal-cancer-in-israel-has-unique-clinico-pathological-features-a-retrospective-study
#9
Michal Sarfaty, Esty Lankry, Assaf Moore, Noga Kurman, Ofer Purim, Yulia Kundel, Irit Ben-Aharon, Gali Perl, Olga Ulitsky, Noa Gordon, Aaron Sulkes, Nikolai Menasherov, Hanoch Kashtan, Baruch Brenner
Introduction: Data regarding esophageal cancer (EC) in Israel are limited. The aim of this study was hence to characterize this entity in the Israeli population and to compare it to the literature. Patients/Methods: This is a retrospective study of all consecutive EC patients treated at our institution between 1997-2013. Data were retrieved from patients' medical files. Results: Two hundred patients were included. The median age at diagnosis was 70.5 years; 63.5% were males; 63% were Ashkenazi Jews, 29% were Sephardic Jews, and 0...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28887506/introduced-ascidians-harbor-highly-diverse-and-host-specific-symbiotic-microbial-assemblages
#10
James S Evans, Patrick M Erwin, Noa Shenkar, Susanna López-Legentil
Many ascidian species have experienced worldwide introductions, exhibiting remarkable success in crossing geographic borders and adapting to local environmental conditions. To investigate the potential role of microbial symbionts in these introductions, we examined the microbial communities of three ascidian species common in North Carolina harbors. Replicate samples of the globally introduced species Distaplia bermudensis, Polyandrocarpa anguinea, and P. zorritensis (n = 5), and ambient seawater (n = 4), were collected in Wrightsville Beach, NC...
September 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28886318/new-insights-into-the-expression-profile-of-microrna-34c-and-p53-in-infertile-men-spermatozoa-and-testicular-tissue
#11
S Rahbar, M G Novin, E Alizadeh, V Shahnazi, F Pashaei-Asl, Y A AsrBadr, L Farzadi, E Ebrahimie, M Pashaiasl
Spermatogenesis is proliferation and differentiation processes of stem spermatogonia into mature spermatozoa controlled by the genes responsible for transcription and post transcription levels. MicroRNAs (miRNA) are  the key factors during gene expression in RNA silencing and post-transcriptional regulation. They play main roles in regulation of early and late spermatogenesis, and reproduction. In this study, we investigate the role of miRNAs in infertile males.The patients were assigned to five groups based on semen analysis (n=55), including normozoospermic (N), moderate oligoasthenoteratozoospermic (MOAT), severe oligoasthenoteratozoospermic (SOAT), obstructive azoospermia (OA) and non-obstructive azoospermia (NOA)...
August 30, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28884386/association-between-cardiac-autonomic-control-and-cognitive-performance-among-patients-post-stroke-and-age-matched-healthy-controls-an-exploratory-pilot-study
#12
Noa Raphaely Beer, Nachum Soroker, Nathan M Bornstein, Michal Katz Leurer
Associations between autonomic nervous system health and cognitive performance have been described in different populations. Autonomic disturbances are a common phenomenon in patients post stroke. Little is known about the relationship between post stroke disturbances of the autonomic nervous system and the commonly occurring disturbances of cognitive functions revealed by victims of stroke. To assess the association between heart rate variability (HRV) and cognitive performance among patients post ischemic stroke and healthy age-matched controls, 13 patients post first-ever ischemic stroke aged 40-80 years and 15 age-matched healthy controls were evaluated...
September 7, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28878985/task-allocation-and-site-fidelity-jointly-influence-foraging-regulation-in-honeybee-colonies
#13
Thiago Mosqueiro, Chelsea Cook, Ramon Huerta, Jürgen Gadau, Brian Smith, Noa Pinter-Wollman
Variation in behaviour among group members often impacts collective outcomes. Individuals may vary both in the task that they perform and in the persistence with which they perform each task. Although both the distribution of individuals among tasks and differences among individuals in behavioural persistence can each impact collective behaviour, we do not know if and how they jointly affect collective outcomes. Here, we use a detailed computational model to examine the joint impact of colony-level distribution among tasks and behavioural persistence of individuals, specifically their fidelity to particular resource sites, on the collective trade-off between exploring for new resources and exploiting familiar ones...
August 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28878756/analysis-of-microbial-functions-in-the-rhizosphere-using-a-metabolic-network-based-framework-for-metagenomics-interpretation
#14
Shany Ofaim, Maya Ofek-Lalzar, Noa Sela, Jiandong Jinag, Yechezkel Kashi, Dror Minz, Shiri Freilich
Advances in metagenomics enable high resolution description of complex bacterial communities in their natural environments. Consequently, conceptual approaches for community level functional analysis are in high need. Here, we introduce a framework for a metagenomics-based analysis of community functions. Environment-specific gene catalogs, derived from metagenomes, are processed into metabolic-network representation. By applying established ecological conventions, network-edges (metabolic functions) are assigned with taxonomic annotations according to the dominance level of specific groups...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28875415/connective-tissue-growth-factor-ctgf-in-age-related-vascular-pathologies
#15
REVIEW
Zoltan Ungvari, Marta Noa Valcarcel-Ares, Stefano Tarantini, Andriy Yabluchanskiy, Gábor A Fülöp, Tamas Kiss, Anna Csiszar
Connective tissue growth factor (CTGF, also known as CCN2) is a matricellular protein expressed in the vascular wall, which regulates diverse cellular functions including cell adhesion, matrix production, structural remodeling, angiogenesis, and cell proliferation and differentiation. CTGF is principally regulated at the level of transcription and is induced by mechanical stresses and a number of cytokines and growth factors, including TGFβ. In this mini-review, the role of age-related dysregulation of CTGF signaling and its role in a range of macro- and microvascular pathologies, including pathogenesis of aorta aneurysms, atherogenesis, and diabetic retinopathy, are discussed...
September 5, 2017: GeroScience
https://www.readbyqxmd.com/read/28874128/relationship-of-genetic-causes-and-inhibin-b-in-non-obstructive-azoospermia-spermatogenic-failure
#16
Qing-Jun Chu, Rui Hua, Chen Luo, Qing-Jie Chen, Biao Wu, Song Quan, Yong-Tong Zhu
BACKGROUND: Chromosomal disorders in non obstructive azoospermia (NOA) may have an important influence on spermatogenesis, which may be reflected by the serum inhibin B levels. Till now, few studies have concerned the relationship of genetic causes and inhibin B in NOA. METHODS: In this retrospective study, 322 men with NOA in Center for Reproductive Medicine, Nanfang Hospital, Southern Medical University were collected. The level of follicle stimulating hormone (FSH), inhibin B, Y chromosome microdeletion test (YCMD) and karyotype were measured...
September 6, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/28872332/the-road-to-extremism-field-and-experimental-evidence-that-significance-loss-induced-need-for-closure-fosters-radicalization
#17
David Webber, Maxim Babush, Noa Schori-Eyal, Anna Vazeou-Nieuwenhuis, Malkanthi Hettiarachchi, Jocelyn J Bélanger, Manuel Moyano, Humberto M Trujillo, Rohan Gunaratna, Arie W Kruglanski, Michele J Gelfand
The present studies examined the hypothesis that loss of personal significance fuels extremism via the need for cognitive closure. Situations of significance loss-those that make one feel ashamed, humiliated, or demeaned-are inconsistent with the desire for a positive self-image, and instill a sense of uncertainty about the self. Consequently, individuals become motivated to seek certainty and closure that affords the restoration of personal significance. Extremist ideologies should thus increase in appeal, because they promise clear-cut strategies for such restoration...
September 4, 2017: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/28865469/comics-as-an-educational-tool-for-children-with-juvenile-idiopathic-arthritis
#18
Amir Mendelson, Noa Rabinowicz, Yonit Reis, Gil Amarilyo, Liora Harel, Philip J Hashkes, Yosef Uziel
BACKGROUND: This study examined whether the comic book Neta and the Medikidz Explain JIA would improve disease-related knowledge and treatment adherence among patients with juvenile idiopathic arthritis (JIA). METHODS: In this prospective cohort study, JIA patients answered 20 multiple-choice knowledge questions about their disease, before and after reading the comic book. Demographic, clinical, health-related quality of life and adherence data were recorded and correlated to the responses...
September 2, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28860999/a-method-sustaining-the-bioelectric-biophysical-and-bioenergetic-function-of-cultured-rabbit-atrial-cells
#19
Noa Kirschner Peretz, Sofia Segal, Limor Arbel-Ganon, Ronen Ben Jehuda, Yuval Shemer, Binyamin Eisen, Moran Davoodi, Ofer Binah, Yael Yaniv
Culturing atrial cells leads to a loss in their ability to be externally paced at physiological rates and to maintain their shape. We aim to develop a culture method that sustains the shape of atrial cells along with their biophysical and bioenergetic properties in response to physiological pacing. We hypothesize that adding 2,3-Butanedione 2-monoxime (BDM), which inhibits contraction during the culture period, will preserve these biophysical and bioenergetic properties. Rabbit atrial cells were maintained in culture for 24 h in a medium enriched with a myofilament contraction inhibitor, BDM...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28860163/proximal-tubular-cannabinoid-1-receptor-regulates-obesity-induced-ckd
#20
Shiran Udi, Liad Hinden, Brian Earley, Adi Drori, Noa Reuveni, Rivka Hadar, Resat Cinar, Alina Nemirovski, Joseph Tam
Obesity-related structural and functional changes in the kidney develop early in the course of obesity and occur independently of hypertension, diabetes, and dyslipidemia. Activating the renal cannabinoid-1 receptor (CB1R) induces nephropathy, whereas CB1R blockade improves kidney function. Whether these effects are mediated via a specific cell type within the kidney remains unknown. Here, we show that specific deletion of CB1R in the renal proximal tubule cells did not protect the mice from obesity, but markedly attenuated the obesity-induced lipid accumulation in the kidney and renal dysfunction, injury, inflammation, and fibrosis...
August 31, 2017: Journal of the American Society of Nephrology: JASN
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