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https://www.readbyqxmd.com/read/28795537/proteomics-investigations-into-serum-proteins-adsorbed-by-high-flux-and-low-flux-dialysis-membranes
#1
Shuai Han, Kaiguang Yang, Jingdi Sun, Jianhui Liu, Lihua Zhang, Jiuyang Zhao
PURPOSE: Hemodialysis is one of the most important therapies for patients with uremia, and the dialysis membrane is the predominant factor that impacts the efficiency of dialysis. Here, we investigated protein adsorption on two different membranes to provide a basis for improving dialysis materials. METHODS: Two cases treated with the Polyflux 14L low-flux dialyzer and the Polyflux 140H high-flux dialyzers during two continuous therapies were selected. Four used dialyzers from selected patients were infused with C12Im-Cl to elute the adsorbed proteins...
August 10, 2017: Proteomics. Clinical Applications
https://www.readbyqxmd.com/read/28782347/the-diurnal-pattern-of-salivary-il-1%C3%AE-in-healthy-young-adults
#2
Nur Basirah Ghazali, Michael Steele, David Koh, Adi Idris
Disruption in circadian rhythm affects the production of inflammatory cytokines. Understanding how it behaves in diseased conditions is essential. Despite the role of the interleukin-1β (IL-1β), a potent inflammatory cytokine, in human diseases, little is known about the steady-state circadian rhythm of IL-1β in healthy individuals. This short study investigates the diurnal pattern of salivary IL-1β throughout the day in healthy young adults. Twelve participants provided saliva samples at various times throughout the day...
August 1, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28768500/long-term-safety-and-tolerability-of-tafluprost-0-0015-vs-timolol-0-1-preservative-free-in-ocular-hypertensive-and-in-primary-open-angle-glaucoma-patients-a-cross-sectional-study
#3
Teresa Rolle, Roberta Spinetta, Raffaele Nuzzi
BACKGROUND: The effects of preservatives of antiglaucoma medications on corneal surface and tear function have been widely shown in literature; it's not the same as regards the active compounds themselves. The purpose of our study was to compare Ocular Surface Disease (OSD) signs and symptoms of Tafluprost 0.0015% versus preservative free (PF) Timolol 0.1% eyedrops in ocular hypertensive (OH) and in primary open-angle glaucoma (POAG) patients. METHODS: A cross-sectional study included patients in monotherapy for at least 36 months with Tafluprost 0...
August 3, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28763917/-analysis-of-the-patterns-of-female-breast-cancer-incidence-in-shanghai-2003-2012
#4
C X Wu, Y Zheng, P P Bao, Z Z Huang, M L Zhang, K Gu, Y M Xiang, P Peng, Y M Gong, W J Zhong
Objective: To analyze the patterns of female breast cancer and their incidence in Shanghai during 2003-2012, and to compare them with international data. Methods: The data of female breast cancer cases diagnosed between 2003 and 2012 were collected from the Shanghai Cancer Registry. The record of cancer cases included the patient's name, gender, date of birth, permanent and residential address, diagnosis site or name, histological type, date of first diagnosis, diagnostic basis and diagnostic stage, etc. Data source of cancer incidence of World, Developed Countries, Developing Countries, East Asia and China in 2012 sourced from GLOBOCAN 2012 database of the WHO International Agency for Research on Cancer (IARC); and the data of USA during 2008-2012 was collected from SEER 18 database from Surveillance, Epidemiology, and End Results Program of the National Cancer Institute (NCI)...
August 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28743424/blood-eosinophil-to-basophil-ratio-in-patients-with-sinonasal-polyps-does-it-have-a-clinical-role
#5
Giuseppe Brescia, Umberto Barion, Claudia Zanotti, Francesco Cinetto, Luciano Giacomelli, Alessandro Martini, Gino Marioni
BACKGROUND: In a recent preliminary study, eosinophil and basophil counts were calculated in chronic rhinosinusitis with nasal polyps (CRSwNP) using conventional histologic and immunohistochemical methods. The tissue eosinophil-to-basophil ratio differed in the CRSwNP endotypes considered. OBJECTIVE: To compare the blood eosinophil-to-basophil ratio (bEBR) in a large series of patients with CRSwNP with that in a control group of consecutive rhinological patients with no evidence of nasal, paranasal, or systemic inflammatory disorders...
July 22, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28731072/-evaluation-of-the-results-of-the-prevention-program-protect-your-voice-implemented-by-the-greater-poland-center-of-occupational-medicine-of-poznan
#6
Magdalena Jałowska, Grażyna Wośkowiak, Bożena Wiskirska-Woźnica
BACKGROUND: The aim of the study was to evaluate the rationale for training in voice emission and voice prophylaxis among teachers and to assess the effects of voice disorders rehabilitation in the selected group of teachers participating in the program "Protect your voice." MATERIAL AND METHODS: An anonymous survey was conducted among 463 teachers participating in the training part of the program. The effectivness of rehabilitation of teachers with occupational voice disorders was evaluated among 51 subjects (average age: 43 years) taking part in diagnostic and rehabilitation part of the program...
July 26, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28727128/transvaginal-six-arm-mesh-opur-in-women-with-apical-pelvic-organ-prolapse-analysis-of-short-term-results-pelvic-floor-ultrasound-evaluation
#7
Tomasz Kluz, Edyta Wlaźlak, Grzegorz Surkont
OBJECTIVES: Analysis of feasibility, efficacy and short-term results after six-arm transvaginal mesh OPUR implantation in women with apical prolapse. MATERIAL AND METHODS: The same surgeon operated all of 39 women using mesh OPUR. Preoperatively patients had a standardized interview and clinical examination. Intraoperative and postoperative complications were analyzed. Postoperative evaluation included standardized interview, clinical examination and standardized pelvic floor ultrasound performed with 2D transvaginal probe and 4D abdominal probe...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28714830/efficiency-of-inpatient-orthopedic-surgery-in-japan-a-medical-claims-database-analysis
#8
Yoshinori Nakata, Tatsuya Yoshimura, Yuichi Watanabe, Hiroshi Otake, Giichiro Oiso, Tomohiro Sawa
Purpose The purpose of this paper is to determine the characteristics of healthcare facilities that produce the most efficient inpatient orthopedic surgery using a large-scale medical claims database in Japan. Design/methodology/approach Reimbursement claims data were obtained from April 1 through September 30, 2014. Input-oriented Banker-Charnes-Cooper model of data envelopment analysis (DEA) was employed. The decision-making unit was defined as a healthcare facility where orthopedic surgery was performed...
July 10, 2017: International Journal of Health Care Quality Assurance
https://www.readbyqxmd.com/read/28709613/a-regional-registry-study-of-216-patients-investigating-if-patient-satisfaction-after-total-knee-arthroplasty-changes-over-a-time-period-of-five-to-20years
#9
Odei Shannak, Jeya Palan, Colin Esler
AIMS: To determine the temporal changes in patient dissatisfaction following primary knee arthroplasty surgery (TKA). PATIENTS AND METHODS: Three hundred and ninety patients that had previously indicated they were either dissatisfied or unsure with their TKA at one-year post-surgery in our region were mailed a simple questionnaire in addition to the Oxford Knee Score and EQ-5D. RESULTS: A 55% response rate was achieved. The mean follow-up time period was 9...
August 2017: Knee
https://www.readbyqxmd.com/read/28702055/evaluation-of-sensibility-threshold-for-interocclusal-thickness-of-patients-wearing-complete-dentures
#10
Kujtim Sh Shala, Linda J Dula, Teuta Pustina-Krasniqi, Teuta Bicaj, Enis F Ahmedi, Zana Lila-Krasniqi, Arlinda Tmava-Dragusha
OBJECTIVE: The aim of this study was to evaluate sensibility threshold for interocclusal thickness in experienced and nonexperienced denture wearers after the insertion of new complete dentures. MATERIALS AND METHODS: A total of 88 patients with complete dentures have participated in this study. The research was divided into two experimental groups, compared with the previous experience prosthetic dental treatment. The sensibility threshold for interocclusal thickness was measured with metal foil with 8 μm thickness and width of 8 mm, placed between the upper and lower incisor region...
2017: International Journal of Dentistry
https://www.readbyqxmd.com/read/28700022/permanent-education-in-healthcare-services-educational-activities-developed-in-the-state-of-minas-gerais-brazil
#11
Roseni Rosângela de Sena, Maria José Cabral Grillo, Lizziane d'Ávila Pereira, Stephanie Marques Moura Franco Belga, Bruna Dias França, Camila Poliana de Freitas
Objective: To analyse educational activities carried out in the state of Minas Gerais, Brazil, considered permanent education in healthcare. Method: This is a mixed methods study with a qualitative approach and the participation of 492 municipal health departments. Data were collected in March and October 2014 through interviews available online. The data were tabulated using Excel software. The data were subjected to thematic content analysis and statistic descriptive analysis...
July 6, 2017: Revista Gaúcha de Enfermagem
https://www.readbyqxmd.com/read/28699163/conventional-sunscreen-application-does-not-lead-to-sufficient-body-coverage
#12
Z Jovanovic, Th Schornstein, A Sutor, G Neufang, R Hagens
OBJECTIVE: This study aimed to assess sunscreen application habits and relative body coverage after single whole body application. METHODS: Fifty-two healthy volunteers were asked to use the test product once, following their usual sunscreen application routine. Standardized UV photographs (UVP), which were evaluated by Image Analysis (IA), were conducted before and immediately after product application to evaluate relative body coverage. In addition to these procedures, the volunteers completed an online self-assessment questionnaire (SAS) to assess sunscreen usage habits...
July 12, 2017: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/28691410/the-risk-of-plasma-vitamin-a-c-e-and-d-deficiency-in-patients-with-metabolic-syndrome-a-case-control-study
#13
Małgorzata Maria Godala, Izabela Materek-Kuśmierkiewicz, Dariusz Moczulski, Maciej Rutkowski, Franciszek Szatko, Ewelina Gaszyńska, Sławomir Tokarski, Jan Kowalski
BACKGROUND: The increasing incidence of metabolic diseases such as obesity or diabetes made them a major public health problem. Increasing oxidative stress induced by reactive oxygen species , which initiate the oxidative adverse changes in the cell, is mentioned, among other risk factors, to underlie these diseases. Vitamin A, C and E are listed among non-enzymatic mechanisms counteracting this phenomenon. Vitamin D deficiency is also associated with cardiovascular diseases. OBJECTIVES: The aim of the study was to assess the risk of vitamin A, C, E and D deficit in plasma of metabolic syndrome (MS) patients...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28685720/effect-of-platelet-derived-p-selectin-on-neutrophil-recruitment-in-a-mouse-model-of-sepsis-induced-acute-kidney-injury
#14
Xiu-Hua Li, Yong-Bing Qian, Xiao-Xiao Meng, Rui-Lan Wang
BACKGROUND: Acute kidney injury (AKI) is a severe disease in critically ill patients. Neutrophil infiltration into kidney was associated with the development of AKI, and P-selectin may be involved in the process of neutrophil recruitment in kidney. This study aimed to explore the potential effect of platelet-derived P-selectin on neutrophil recruitment in a mouse model of sepsis-induced AKI. METHODS: A total of 30 C57BL/6 male mice were divided into five groups (n = 6 in each): sham group, sepsis group, anti-Ly6G group, anti-P-selectin group, and platelet depletion group...
July 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28684901/comparison-of-posttransplant-outcomes-in-patients-with-no-acute-or-chronic-amiodarone-use-before-heart-transplantation
#15
Rasmus Rivinius, Matthias Helmschrott, Arjang Ruhparwar, Fabrice F Darche, Dierk Thomas, Tom Bruckner, Hugo A Katus, Andreas O Doesch
BACKGROUND: Major concerns about the safety of pretransplant amiodarone use have been raised. As a result of its long half-life, the cardiac allograft is exposed to amiodarone posing potential risks such as bradycardia, requirement for pacemaker implantation, or increased mortality after heart transplantation (HTX). OBJECTIVE: The aim of this study is to investigate the posttransplant outcomes of patients with no, acute, or chronic amiodarone use before HTX. METHODS: This retrospective single-center study included 530 adult patients who received HTX between 06/1989 and 12/2012...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28683829/%C3%AE-glucosidase-inhibitor-miglitol-attenuates-glucose-fluctuation-heart-rate-variability-and-sympathetic-activity-in-patients-with-type-2-diabetes-and-acute-coronary-syndrome-a-multicenter-randomized-controlled-macs-study
#16
Michio Shimabukuro, Atsushi Tanaka, Masataka Sata, Kazuoki Dai, Yoshisato Shibata, Yohei Inoue, Hiroki Ikenaga, Shinji Kishimoto, Kozue Ogasawara, Akira Takashima, Toshiyuki Niki, Osamu Arasaki, Koichi Oshiro, Yutaka Mori, Masaharu Ishihara, Koichi Node
BACKGROUND: Little is known about clinical associations between glucose fluctuations including hypoglycemia, heart rate variability (HRV), and the activity of the sympathetic nervous system (SNS) in patients with acute phase of acute coronary syndrome (ACS). This pilot study aimed to evaluate the short-term effects of glucose fluctuations on HRV and SNS activity in type 2 diabetes mellitus (T2DM) patients with recent ACS. We also examined the effect of suppressing glucose fluctuations with miglitol on these variables...
July 6, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/28662266/cost-effectiveness-of-regorafenib-as-second-line-therapy-for-patients-with-advanced-hepatocellular-carcinoma
#17
Neehar D Parikh, Amit G Singal, David W Hutton
BACKGROUND: Regorafenib, a multikinase inhibitor, has demonstrated prolonged survival by 2.8 months as a second-line agent in patients with hepatocellular carcinoma (HCC) who progress on sorafenib therapy. The objective of the current study was to examine the cost effectiveness of regorafenib for the treatment of HCC. METHODS: The authors constructed a Markov simulation model of patients with unresectable HCC and Child-Pugh A cirrhosis who received treatment with regorafenib versus best supportive care...
June 29, 2017: Cancer
https://www.readbyqxmd.com/read/28662209/narrow-band-imaging-nbi-for-improving-the-assessment-of-vocal-fold-leukoplakia-and-overcoming-the-umbrella-effect
#18
H Klimza, J Jackowska, M Tokarski, K Piersiala, M Wierzbicka
BACKGROUND: It is crucial to find a balance between functional and oncological outcome when choosing an adequate method for the management of vocal fold leukoplakia. Therefore, a detailed examination is a milestone in the decision-making process. AIM: To examine whether narrow-band imaging (NBI) can be helpful in vocal fold assessment in the case of leukoplakia and how to overcome the "umbrella effect"- understood as the submucosal vascular pattern hidden under the plaque...
2017: PloS One
https://www.readbyqxmd.com/read/28646919/determinants-of-modern-contraceptive-practice-in-yaound%C3%A3-cameroon-a-community-based-cross-sectional-study
#19
Philip Nana Njotang, Martin Ndinakie Yakum, Atem Bethel Ajong, Marie José Essi, Ebile Walter Akoh, Nzene Edmond Mesumbe, Simon Ako, Enow Robinson Mbu
BACKGROUND: Despite numerous efforts put in place to increase modern contraceptive use in Cameroon as a means to fight maternal and infant mortality, the prevalence of modern contraception has shown only a slow increase and maternal mortality is constantly rising. This paper attempts to identify barriers to contraceptive use in Biyem-Assi, Yaoundé-Cameroon so as to clearly define in which domain and how to intervene concerning contraceptive use in Cameroon. METHODS: It was a community-based cross sectional study involving a two-steps cluster sampling...
June 24, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28639871/an-innovative-streaming-video-system-with-a-point-of-view-head-camera-transmission-of-surgeries-to-smartphones-and-tablets-an-educational-utility
#20
Rafael Oliveira Chaves, Pedro Armando Valente de Oliveira, Luciano Chaves Rocha, Joacy Pedro Franco David, Sanmari Costa Ferreira, Alex de Assis Santos Dos Santos, Rômulo Müller Dos Santos Melo, Edson Yuzur Yasojima, Marcus Vinicius Henriques Brito
PURPOSE: In order to engage medical students and residents from public health centers to utilize the telemedicine features of surgery on their own smartphones and tablets as an educational tool, an innovative streaming system was developed with the purpose of streaming live footage from open surgeries to smartphones and tablets, allowing the visualization of the surgical field from the surgeon's perspective. The current study aims to describe the results of an evaluation on level 1 of Kirkpatrick's Model for Evaluation of the streaming system usage during gynecological surgeries, based on the perception of medical students and gynecology residents...
June 1, 2017: Surgical Innovation
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