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Intraocular pressure

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https://www.readbyqxmd.com/read/28098737/increased-intraocular-pressure-is-a-risk-factor-for-unexplained-visual-loss-during-silicone-oil-endotamponade
#1
Marvin Marti, Richard Walton, Christian Böni, Sandrine A Zweifel, Marc Stahel, Daniel Barthelmes
PURPOSE: To identify the incidence rate and risk factors for unexplained visual loss associated with silicone oil endotamponade used during primary repair of macula-sparing rhegmatogenous retinal detachments. METHODS: This retrospective cohort study included patients undergoing pars plana vitrectomy for primary surgical repair of macula-sparing rhegmatogenous retinal detachments in whom silicone oil endotamponade was used. The primary outcome measure was the incidence rate of unexplained visual loss and identification of risk factors associated with vision loss...
January 16, 2017: Retina
https://www.readbyqxmd.com/read/28098579/xen-gel-stent-internal-ostium-occlusion-ab-interno-revision
#2
Nuno Pinto Ferreira, Luis Abegão Pinto, Carlos Marques-Neves
Minimally invasive glaucoma surgery aims to provide a safer and less-invasive means of reducing IOP compared with traditional surgery, with the goal of reducing the need for topical medications. The XEN gel stent is an ab-interno minimally invasive glaucoma surgery device that approaches intraocular pressure reduction by creating a subconjunctival drainage pathway. As with any new device there is lack of experience and knowledge about its long-term results in terms of efficacy, technique, and complications...
January 16, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28097295/association-of-systemic-medication-use-with-intraocular-pressure-in-a-multiethnic-asian-population-the-singapore-epidemiology-of-eye-diseases-study
#3
Henrietta Ho, Yuan Shi, Jacqueline Chua, Yih-Chung Tham, Sing Hui Lim, Tin Aung, Tien Yin Wong, Ching-Yu Cheng
Importance: There is limited understanding of the associations between systemic medication use and intraocular pressure (IOP) in the general population. Objective: To examine the association between systemic medication use and IOP in a multiethnic Asian population. Design, Setting, and Participants: In this post hoc analysis of the Singapore Epidemiology of Eye Diseases study, a population-based study of 10 033 participants (78.7% response rate) from 3 racial/ethnic groups (Chinese [recruited from February 9, 2009, through December 19, 2011], Malays [recruited from August 16, 2004, though July 10, 2006], and Indians [recruited from May 21, 2007, through December 29, 2009]), participants with glaucoma, previous ocular surgery, or trauma and an IOP asymmetry greater than 5 mm Hg between eyes were excluded...
January 12, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28097290/the-association-of-systemic-medication-and-disease-with-intraocular-pressure
#4
Paul J Foster, Anthony P Khawaja
No abstract text is available yet for this article.
January 12, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28096654/comparison-of-visian-toric-collamer-lens-and-toric-acrylic-intraocular-lens-implantation-for-the-treatment-of-myopia-with-astigmatism
#5
Hatem Ammar, Mohamed Anbar, Marwa M Abdellah
PURPOSE: To compare the efficacy and outcome of phakic toric implantable collamer lens (TICL) and refractive clear lens extraction with AcrySof Toric intraocular lens (TIOL) implantation for the treatment of myopic astigmatism. PATIENTS AND METHODS: This study assessed eyes with myopic astigmatism >-1 D and ≤-4 D with a spherical equivalent >10 D or <10 D if the patients were unsuitable for corneal refractive surgery. These eyes were divided into group A, in which Visian Toric ICL™ Phakic TICL was implanted, and group B, which involved clear lens extraction with implantation of an AcrySof IQ toric SN60T3-9™ IOL...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28095506/a-comparison-of-the-corrected-intraocular-pressure-obtained-by-the-corvis-st-and-reichert-7cr-tonometers-in-glaucoma-patients
#6
Yoshitaka Nakao, Yoshiaki Kiuchi, Satoshi Okimoto
The purpose of the study was to investigate the accuracy of two corrected intraocular pressure (IOP) measurements by Corvis Scheimpflug Technology (CST)-IOPpachy and by corneal-compensated IOP (IOPcc) using the Reichert 7CR (7CR) tonometers. We also investigated the effects of corneal anatomical and structural parameters on the IOP measurements. The participants included 90 primary open-angle glaucoma patients. We assessed the IOP measurements, obtained by the CST, 7CR, and Goldmann applanation tonometer (GAT), using a paired t-test with Bonferroni correction, Bland-Altman plots, and multiple regression analyses...
2017: PloS One
https://www.readbyqxmd.com/read/28094584/cytoskeletal-alteration-and-change-of-retinal-nerve-fiber-layer-birefringence-in-hypertensive-retina
#7
Xiang-Run Huang, Robert W Knighton, Ye Z Spector, William J Feuer
PURPOSE: Glaucoma damages the retinal nerve fiber layer (RNFL). Both RNFL thickness and retardance can be used to assess the damage, but birefringence, the ratio of retardance to thickness, is a property of the tissue itself. This study investigated the relationship between axonal cytoskeleton and RNFL birefringence in retinas with hypertensive damage. MATERIALS AND METHODS: High intraocular pressure (IOP) was induced unilaterally in rat eyes. RNFL retardance in isolated retinas was measured...
January 17, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28094315/the-usefulness-of-corvisst-tonometry-and-the-ocular-response-analyzer-to-assess-the-progression-of-glaucoma
#8
Masato Matsuura, Kazunori Hirasawa, Hiroshi Murata, Shunsuke Nakakura, Yoshiaki Kiuchi, Ryo Asaoka
Corneal Visualization Scheimpflug Technology (CST) and Ocular Response Analyzer (ORA) measurements were carried out in 105 eyes of 69 patients with primary open-angle glaucoma. All patients had axial length (AL), central corneal thickness (CCT), intraocular pressure (IOP) with Goldmann applanation tonometry (GAT) and eight visual fields (VF)s with the Humphrey Field Analyzer. VF progression was summarized using a time trend analysis of mean total deviation (mTD) and the association between mTD progression rate and a number of ocular parameters (including CST and ORA measurements) was assessed using mixed linear regression analysis...
January 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28092395/intraocular-pressure-changes-following-intravitreal-melphalan-and-topotecan-for-the-treatment-of-retinoblastoma-with-vitreous-seeding
#9
Matthew D Karl, Jasmine H Francis, Saipriya Iyer, Brian Marr, David H Abramson
PURPOSE: To investigate the impact of intravitreal chemotherapy on intraocular pressure (IOP) in children with retinoblastoma. METHODS: This was a retrospective study of 10 eyes of 10 patients with retinoblastoma (7 males, 3 females, mean age: 33.6 ± 9.4 months) with vitreous seeding injected with intravitreal melphalan and topotecan. IOP was measured with Tono-pen (Reichert, Inc., Buffalo, NY) at baseline prior to injecting and then repeatedly following each intravitreal injection...
January 13, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28092314/novel-technique-for-subretinal-fluid-drainage-with-chandelier-assisted-scleral-buckle-surgery-cannula-controlled-drainage
#10
Abdulelah A Al-Abdullah
PURPOSE: To report a novel technique for subretinal fluid drainage in scleral buckle surgery. METHODS: A 26-gauge intravenous cannula with its needle was used to puncture the sclera; then, the needle (metallic part) was withdrawn to further introduce the cannula into the subretinal space. In addition, we describe using the 25-gauge microcannula of the chandelier light to inject the balanced salt solution to help restore the intraocular pressure and push the subretinal fluid through the intravenous cannula under direct visualization...
January 13, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28088634/chitosan-g-poly-n-isopropylacrylamide-copolymers-as-delivery-carriers-for-intracameral-pilocarpine-administration
#11
Jui-Yang Lai, Li-Jyuan Luo
This study reports, for the first time, the development of a chitosan-g-poly(N-isopropylacrylamide) (Chi-PN) biodegradable in situ gelling delivery system for ocular pilocarpine administration through intracameral injection. The number of thermo-responsive polymer segments grafted onto the chitosan via carbodiimide-mediated formation of amide linkages was greatly affected by varying the feeding amount of carboxyl-terminated poly(N-isopropylacrylamide) in the synthesis, thereby determining the phase transition temperature and enzymatic degradability of Chi-PN materials...
January 11, 2017: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/28088510/association-between-nocturnal-blood-pressure-dips-and-optic-disc-hemorrhage-in-patients-with-normal-tension-glaucoma
#12
Junki Kwon, Jinyoung Lee, Jaewan Choi, Dawoon Jeong, Michael S Kook
PURPOSE: To investigate the effect of nocturnal blood pressure (BP) dips on the occurrence of optic disc hemorrhage (ODH) in normal-tension glaucoma (NTG) patients and determine whether ODH is associated with greater likelihood of visual field progression (VFP). DESIGN: Prospective case-control study. METHODS: This study enrolled 698 eyes of 349 consecutive NTG patients who were ≥40 years old, underwent 24 hour intraocular pressure and ambulatory BP monitoring in the habitual position, were examined for ODH every 4-6 months with optic disc photography, and had ≥ five reliable VF tests with minimum follow-up of 3 years...
January 11, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28087345/steroid-induced-glaucoma-in-the-pediatric-population
#13
REVIEW
Brenda Nuyen, Robert N Weinreb, Shira L Robbins
Steroid medications may cause elevation of intraocular pressure, sometimes with permanent damage to the optic nerve. These therapies, via various routes of administration, are commonly prescribed for children, but the potential sequelae of elevated intraocular pressure and glaucomatous optic nerve damage can be even more severe and devastating in children than in adults. This review discusses the pathophysiology and potential risk factors, including the impact of intraocular pressure elevation via the different common routes of administration of steroids, clinical evaluation, and management of steroid response and steroid-induced glaucoma in children...
January 10, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28081326/the-effect-of-deep-sclerectomy-on-ocular-blood-flow-a-6-month-clinical-trial
#14
Arzu Özsoy, Murat Sinan Sarıcaoğlu, Mehtap Çavuşoğlu
BACKGROUND/AIM: To investigate the effect of deep sclerectomy on retrobulbar blood flow. MATERIALS AND METHODS: This prospective study included 20 eyes of 20 patients with open angle glaucoma. Color Doppler imaging (CDI) examinations were performed before and 2, 12, and 24 weeks after deep sclerectomy. Peak systolic velocity (PSV), end diastolic velocity (EDV), and resistance index (RI) were measured for the ophthalmic artery (OA), central retinal artery (CRA), and temporal and nasal short posterior ciliary arteries (SPCAs) at each examination and the results were compared...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28081305/biocompatible-multifunctional-black-silicon-for-implantable-intraocular-sensor
#15
Jeong Oen Lee, Vinayak Narasimhan, Juan Du, Blaise Ndjamen, David Sretavan, Hyuck Choo
Multifunctional black-silicon (b-Si) integrated on the surface of an implantable intraocular pressure sensor significantly improves sensor performance and reliability in six-month in vivo studies. The antireflective properties of b-Si triples the signal-to-noise ratio and increases the optical readout distance to a clinically viable 12 cm. Tissue growth and inflammation response on the sensor is suppressed demonstrating desirable anti-biofouling properties.
January 12, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28081184/intraocular-pressure-lowering-effect-of-latanoprost-is-hampered-by-defective-cervical-lymphatic-drainage
#16
Young Kook Kim, Kyeong Ik Na, Jin Wook Jeoung, Ki Ho Park
PURPOSE: To evaluate whether defects in cervical lymphatic drainage influence the intraocular pressure (IOP)-lowering effect of latanoprost in patients with primary open-angle glaucoma (POAG) who have undergone unilateral radical neck dissection (uRND). METHODS: We enrolled (1) bilateral POAG patients who had started (bilateral) latanoprost (0.005%) monotherapy prior to their uRND and (2) treatment-naïve, bilateral glaucoma suspects (GSs) who had undergone the same surgery...
2017: PloS One
https://www.readbyqxmd.com/read/28081172/influence-of-corneal-opacity-on-intraocular-pressure-assessment-in-patients-with-lysosomal-storage-diseases
#17
Joanna Wasielica-Poslednik, Giuseppe Politino, Irene Schmidtmann, Katrin Lorenz, Katharina Bell, Norbert Pfeiffer, Susanne Pitz
AIMS: To investigate an influence of mucopolysaccharidosis (MPS)- and Morbus Fabry-associated corneal opacities on intraocular pressure (IOP) measurements and to evaluate the concordance of the different tonometry methods. METHODS: 25 MPS patients with or without corneal clouding, 25 Fabry patients with cornea verticillata ≥ grade 2 and 25 healthy age matched controls were prospectively included into this study. Outcome measures: Goldmann applanation tonometry (GAT); palpatory assessment of IOP; Goldmann-correlated intraocular pressure (IOPg), corneal-compensated intraocular pressure (IOPcc), corneal resistance factor (CRF) and corneal hysteresis (CH) assessed by Ocular Response Analyzer (ORA); central corneal thickness (CCT) and density assessed with Pentacam...
2017: PloS One
https://www.readbyqxmd.com/read/28079655/microarchitecture-of-schlemm-canal-before-and-after-selective-laser-trabeculoplasty-in-enhanced-depth-imaging-optical-coherence-tomography
#18
Alon Skaat, Michael S Rosman, Jason L Chien, Mark P Ghassibi, Jeffrey M Liebmann, Robert Ritch, Sung Chul Park
PURPOSE: To characterize the in vivo effect of selective laser trabeculoplasty (SLT) on the Schlemm canal (SC) in eyes with primary open-angle glaucoma (POAG). MATERIALS AND METHODS: Eighty-one serial horizontal enhanced depth imaging optical coherence tomograph B-scans (interval between B-scans, ∼35 μm) of the nasal corneoscleral limbus were obtained before and 4 weeks after SLT. Fifty B-scans in the overlapping regions before and after SLT were selected for analysis based on the structures of aqueous and blood vessels as landmarks...
January 10, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28075618/rodent-models-of-glaucoma-and-their-applicability-for-drug-discovery
#19
Renu Agarwal, Puneet Agarwal
Rodents have widely been used to represent glaucomatous changes both in the presence and absence of elevated intraocular pressure (IOP) as they offer clear advantages over other animal species. IOP elevation is commonly achieved by creating an obstruction in the aqueous outflow pathways, consequently leading to retinal ganglion cell (RGCs) and optic nerve (ON) damage, the hallmark of glaucoma. These changes may also be achieved in the absence of elevated IOP by directly inflicting injury to retina or ON. Areas covered: This paper presents a summary of currently used rodent models of glaucoma...
January 11, 2017: Expert Opinion on Drug Discovery
https://www.readbyqxmd.com/read/28074538/ultrasound-biomicroscopy-and-tonometry-in-ophthalmologically-normal-pigeon-eyes
#20
Sangwan Park, Seonmi Kang, Jaegook Lim, Eunjin Park, Taekjin Nam, Seowoo Jeong, Kangmoon Seo
OBJECTIVE: To evaluate the feasibility of ultrasound biomicroscopy (UBM) and tonometry in pigeons and to provide biometric reference ranges for normal pigeon eyes. ANIMALS STUDIED: Ten pigeons (Columba livia var. domestica) with ophthalmologically normal eyes. PROCEDURES: Ophthalmic examinations, including slit-lamp biomicroscopy and tonometry, were performed to confirm that the eyes were normal. UBM was then performed on the left eye. On each obtained image, the ciliary cleft (CC) length, CC width, and CC area, and iridocorneal angle (ICA) were measured...
January 11, 2017: Veterinary Ophthalmology
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