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https://www.readbyqxmd.com/read/28323675/30-day-readmission-after-pancreatic-resection-a-systematic-review-of-the-literature-and-meta-analysis
#1
Alexander V Fisher, Sara Fernandes-Taylor, Stephanie A Campbell-Flohr, Sam J Clarkson, Emily R Winslow, Daniel E Abbott, Sharon M Weber
OBJECTIVE: The aim of this study was to identify and compare common reasons and risk factors for 30-day readmission after pancreatic resection. BACKGROUND: Hospital readmission after pancreatic resection is common and costly. Many studies have evaluated this problem and numerous discrepancies exist regarding the primary reasons and risk factors for readmission. METHODS: Multiple electronic databases were searched from 2002 to 2016, and 15 relevant articles identified...
March 20, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28323527/design-synthesis-and-anticancer-evaluation-of-novel-pyrazole-pyrazolo-3-4-d-pyrimidine-and-their-glycoside-derivatives
#2
Ibrahim F Nassar, Ahmed F El Farargy, Fathy M Abdelrazek, Nasser S M Ismail
The chalcone derivatives 3a,b were cyclized upon reaction with thiourea to give the pyrazolo[3,4-d]pyrimidine derivatives 5a,b. Condensation of 5a,b and their hydrazide derivatives 8a,b with cyclic and acyclic glucose gave the condensed S- and N-glycosides 7a,b and 9a,b, respectively. Reaction of 3b with ethyl cyanoacetate followed by reaction with cyclic glucose afforded a mixture of the O- and/or N-glycoside isomers 12 and 13, respectively. The pyrazolo[3,4-c]pyrazole derivative 14 was also obtained from the reaction of 3b with hydrazine hydrate...
March 21, 2017: Nucleosides, Nucleotides & Nucleic Acids
https://www.readbyqxmd.com/read/28323423/bioinspired-layer-by-layer-microcapsules-based-on-cellulose-nanofibers-with-switchable-permeability
#3
Thomas Paulraj, Anastasia V Riazanova, Kun Yao, Richard L Andersson, Anette Müllertz, Anna J Svagan
Green, all-polysaccharide based microcapsules with mechanically robust capsule walls and fast, stimuli-triggered and switchable permeability behaviour show great promise in applications based on selective and timed permeability. Taking cue from nature, the build-up and composition of plant primary cell wall inspired the capsule wall assembly, because the primary cell walls in plants exhibit high mechanical properties despite being in a highly hydrated state, primarily owing to cellulose microfibrils. The microcapsules (16 ± 4 µm in diameter) were fabricated using the Layer-by-Layer technique on sacrificial CaCO3 templates, using plant polysaccharides (pectin, cellulose nanofibers and xyloglucan) only...
March 21, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28319679/evaluation-of-body-composition-with-bioimpedence-a-comparison-between-athletic-and-non-athletic-children
#4
Domenico Meleleo, Nicola Bartolomeo, Liliana Cassano, Alessandro Nitti, Giovanna Susca, Giuseppina Mastrototaro, Umberto Armenise, Annapaola Zito, Fiorella Devito, Pietro Scicchitano, Marco Matteo Ciccone
PURPOSE: Conventional Bioelectrical Impedance Analysis (BIA) or Bioelectrical Impedance Vector Analysis (BIVA) can provide direct evaluations of body composition. The purpose of this study was to evaluate lean and fat mass (FM), and hydration of children involved in daily competitive sports. METHODS: 190 non-athletic [8.2-10.5 years] and 29 competitive children [8.0-10.5 years] were enrolled. They were evaluated: at baseline (t0), 6 months (t1) and one year (t2)...
March 20, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28319313/co-creating-a-peer-education-program-to-improve-skin-health-in-older-people-from-diverse-communities-an-innovation-in-health-promotion
#5
Rajna Ogrin, Kathleen Brasher, Jessica Occleston, Jennifer Byrne
OBJECTIVE: Chronic wounds, debilitating and costly to manage, are more common in older people. Prevention is possible through improving skin health. We developed, implemented and evaluated an innovative health promotion program to improve skin health of older adults. METHODS: A one-hour, peer education program was co-created and delivered to culturally diverse community-dwelling older people. A mixed-methods evaluation approach comprised objective measures of skin health and barrier function at commencement and six weeks posteducation, and focus groups posteducation...
March 20, 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/28318362/carbonic-anhydrase-inhibitors-modify-intracellular-ph-transients-and-contractions-of-rat-middle-cerebral-arteries-during-co2-hco3-fluctuations
#6
Jacob K Rasmussen, Ebbe Boedtkjer
The CO2/HCO3(-) buffer minimizes pH changes in response to acid-base loads, HCO3(-) provides substrate for Na(+),HCO3(-)-cotransporters and Cl(-)/HCO3(-)-exchangers, and H(+) and HCO3(-) modify vasomotor responses during acid-base disturbances. We show here that rat middle cerebral arteries express cytosolic, mitochondrial, extracellular, and secreted carbonic anhydrase isoforms that catalyze equilibration of the CO2/HCO3(-) buffer. Switching from CO2/HCO3(-)-free to CO2/HCO3(-)-containing extracellular solution results in initial intracellular acidification due to hydration of CO2 followed by gradual alkalinization due to cellular HCO3(-) uptake...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28317716/a-nano-delivery-system-for-bioactive-ingredients-using-supercritical-carbon-dioxide-and-its-release-behaviors
#7
Wenbei Situ, Xianliang Song, Shucan Luo, Yan Liang
For the purpose of ensuring the bioavailability of bioactive ingredients, a nano-delivery system with low toxicity was developed using supercritical carbon dioxide (SC-CO2). Compared to thin-film hydration (TFH), obtaining nano-scale liposomes is easier using SC-CO2. The characteristic of these liposomes was also demonstrated by the analysis of particle size and morphology. An in vitro release study showed that liposomes produced using SC-CO2 were resistant to low pH in simulated gastric conditions. In a simulated intestinal environment, enteric solubility of these liposomes was enhanced, which are important properties for controlled releasing bioactive ingredient...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28317241/organogels-from-double-chained-vitamin-c-amphiphilic-derivatives
#8
Pierandrea Lo Nostro, Elia Tempestini, Martina Bucci, Vincenzo Mastromartino, Marianna Gori, Damiano Tanini, Moira Ambrosi, Emiliano Fratini, Antonella Capperucci
We report on the synthesis and physico-chemical characterization of double chained amphiphilic compounds obtained from vitamin C: Di-alkanoyl-5,6-O-ascorbic acid esters, Di-ASCn, with n = 8, 10 and 12. The acetyl-5-dodecanoyl-6-ascorbic acid ester was synthesized and investigated for comparison. These products are quite insoluble in water and in polar solvents, while they form homogeneous dispersions in cyclohexane. By cooling, these dispersions turn into a gel-like phase. DSC, FTIR, and SAXS/WAXS experiments were carried out to investigate the properties of the pure solids and of their liquid dispersions...
March 20, 2017: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/28316361/iminophosphanes-synthesis-rhodium-complexes-and-ruthenium-ii-catalyzed-hydration-of-nitriles
#9
Mark K Rong, Koen van Duin, Tom van Dijk, Jeroen J M de Pater, Berth-Jan Deelman, Martin Nieger, A W Ehlers, J Chris Slootweg, Koop Lammertsma
Highly stable iminophosphanes, obtained from alkylating nitriles and reaction of the resulting nitrilium ions with secondary phosphanes, were explored as tunable P-monodentate and 1,3-P,N bidentate ligands in rhodium complexes. X-ray crystal structures are reported for both κ(1) and κ(2) complexes with the counterion in one of them being an unusual anionic coordination polymer of silver triflate. The iminophosphane-based ruthenium(II)-catalyzed hydration of benzonitrile in 1,2-dimethoxyethane (180 °C, 3 h) and water (100 °C, 24 h) and under solvent free conditions (180 °C, 3 h) results in all cases in the selective formation of benzamide with yields of up to 96%, thereby outperforming by far the reactions in which the common 2-pyridyldiphenylphosphane is used as the 1,3-P,N ligand...
March 13, 2017: Organometallics
https://www.readbyqxmd.com/read/28316239/facile-preparation-of-titanium-iv-immobilized-hierarchically-porous-hybrid-monoliths
#10
Haiyang Zhang, Junjie Ou, Yating Yao, Hongwei Wang, Zhongshan Liu, Yinmao Wei, Mingliang Ye
Hierarchically porous materials have become a key feature of biological materials and have been widely applied for adsorption or catalysis. Herein, we presented a new approach to directly prepare a phosphate-functionalized hierarchically porous hybrid monolith (HPHM), which simultaneously contained mesopores and macropores. The design was based on the copolymerization of polyhedral oligomeric vinylsilsesquioxanes (vinylPOSS) and vinylphosphonic acid (VPA) by adding degradable polycaprolactone (PCL) additive...
March 18, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28315878/dexamethasone-modifies-cystatin-c-based-diagnosis-of-acute-kidney-injury-during-cisplatin-based-chemotherapy
#11
Timothy J Pianta, John W Pickering, Lena Succar, Melvin Chin, Trent Davidson, Nicholas A Buckley, Fahim Mohamed, Zoltan H Endre
BACKGROUND/AIMS: Plasma cystatin C (pCysC) may be superior to serum creatinine (sCr) as a surrogate of GFR. However, the performance of pCysC for diagnosing acute kidney injury (AKI) after cisplatin-based chemotherapy is potentially affected by accompanying corticosteroid anti-emetic therapy and hydration. METHODS: In a prospective observational study pCysC, sCr, urinary kidney injury molecule-1 (KIM-1), and urinary clusterin were measured over 2 weeks in 27 patients given first-cycle chemotherapy...
March 17, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/28315876/angiotensin-converting-enzyme-ins-del-polymorphism-and-body-composition-the-intermediary-role-of-hydration-status
#12
Laura Bordoni, Valerio Napolioni, Francesca Marchegiani, Emilio Amadio, Rosita Gabbianelli
BACKGROUND: The well-known insertion/deletion polymorphism (rs4646994) of the angiotensin-converting enzyme (ACE) gene has been previously associated with obesity, blood flow, muscular strength, and ACE enzyme activity. Despite the relevant role of ACE in homeostasis, few data are currently available on the relationship between rs4646994 and hydration status. Thus, we tested the association between the ACE Ins/Del polymorphism, body composition, and hydration status in a young Italian population...
March 18, 2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28315446/targeted-delivery-of-morin-a-dietary-bioflavanol-encapsulated-mannosylated-liposomes-to-the-macrophages-of-adjuvant-induced-arthritis-rats-inhibits-inflammatory-immune-response-and-osteoclastogenesis
#13
Farhath Sultana, Manoj Kumar Neog, MahaboobKhan Rasool
The purpose of the study was to develop a liposomal drug delivery system for morin, a dietary polyphenol, in order to target the synovial macrophages and investigate the remission of disease severity in the adjuvant-induced arthritic (AIA) rats. To do so, mannose decorated liposomal morin (ML-Morin) was prepared using the thin film hydration method and the physicochemical properties were characterized. The particle size and zeta potential of liposomal morin (L-Morin) was found to be 127.9nm ± 2.6 and -24.5mV ± 0...
March 14, 2017: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/28306420/ventriculo-ureteral-shunt-insertion-using-percutaneous-nephrostomy-a-novel-minimally-invasive-option-in-a-patient-with-chronic-hydrocephalus-complicated-by-multiple-distal-ventriculoperitoneal-shunt-failures
#14
Ashok Pillai, Georgie Mathew, Sivasankaran Nachimuthu, Sanjeevan Vasudevan Kalavampara
The management of ventriculoperitoneal (VP) shunt failure is a common problem in neurosurgical practice. On occasion, extraperitoneal sites for CSF diversion are required when shunting to the peritoneal cavity has failed after multiple attempts. The authors report a novel minimally invasive procedure allowing cannulation of the ureter for the purpose of ventriculo-ureteral (VU) shunting. Sixteen years prior to presentation, this 46-year-old woman had contracted tuberculous meningitis and had chronic hydrocephalus, with multiple distal shunt failures in recent months...
March 17, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28306250/co2-selective-absorbents-in-air-reverse-lipid-bilayer-structure-forming-neutral-carbamic-acid-in-water-without-hydration
#15
Fuyuhiko Inagaki, Chiaki Matsumoto, Takashi Iwata, Chisato Mukai
Emission gas and air contain not only CO2 but also plentiful moisture, making it difficult to achieve selective CO2 absorption without hydration. To generate absorbed CO2 (wet CO2) under heating, the need for external energy to release the absorbed water has been among the most serious problems in the fields of carbon dioxide capture and storage (CCS) and direct air capture (DAC). We found that the introduction of the hydrophobic phenyl group into alkylamines of CO2 absorbents improved the absorption selectivity between CO2 and water...
March 17, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28306180/selective-nanoscale-mass-transport-across-atomically-thin-single-crystalline-graphene-membranes
#16
Piran R Kidambi, Michael S H Boutilier, Luda Wang, Doojoon Jang, Jeehwan Kim, Rohit Karnik
Atomically thin single crystals, without grain boundaries and associated defect clusters, represent ideal systems to study and understand intrinsic defects in materials, but probing them collectively over large area remains nontrivial. In this study, the authors probe nanoscale mass transport across large-area (≈0.2 cm(2) ) single-crystalline graphene membranes. A novel, polymer-free picture frame assisted technique, coupled with a stress-inducing nickel layer is used to transfer single crystalline graphene grown on silicon carbide substrates to flexible polycarbonate track etched supports with well-defined cylindrical ≈200 nm pores...
March 17, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28304172/-i-ab-initio-i-studies-on-the-clathrate-hydrates-of-some-nitrogen-and-sulfur-containing-gases
#17
Ningru Sun, Zewen Li, Nianxiang Qiu, Xiaohui Yu, Xuran Zhang, Yanjun Li, Longbin Yang, Kan Luo, Qing Huang, Shiyu Du
<i>Ab initio<i> calculations are performed to investigate the host-guest interactions and multiple occupancies of some sulfide (H<sub>2</sub>S, CS<sub>2</sub>) and nitrogen-containing (N<sub>2</sub>, NO and NH<sub>3</sub>) molecules in dodecahedral, tetrakaidecahedral and hexakaidecahedral water cages in this work. Five functionals in the framework of density functional theory are compared and the M06-2X method appears to be the best to predict the binding energies as well as the geometries...
March 17, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28301773/progress-and-potential-of-electron-cryotomography-as-illustrated-by-its-application-to-bacterial-chemoreceptor-arrays
#18
Ariane Briegel, Grant Jensen
Electron cryotomography (ECT) can produce three-dimensional images of biological samples such as intact cells in a near-native, frozen-hydrated state to macromolecular resolution (∼4 nm). Because one of its first and most common applications has been to bacterial chemoreceptor arrays, ECT's contributions to this field illustrate well its past, present, and future. Although X-ray crystallography and nuclear magnetic resonance spectroscopy have revealed the structures of nearly all the individual components of chemoreceptor arrays, ECT has revealed the mesoscale information about how the components are arranged within cells...
February 23, 2017: Annual Review of Biophysics
https://www.readbyqxmd.com/read/28301293/signatures-of-dna-target-selectivity-by-ets-transcription-factors
#19
Gregory M K Poon, Hye Mi Kim
The ETS family of transcription factors is a functionally heterogeneous group of gene regulators that share a structurally conserved, eponymous DNA-binding domain. DNA target specificity derives from combinatorial interactions with other proteins as well as intrinsic heterogeneity among ETS domains. Emerging evidence suggests molecular hydration as a fundamental feature that defines the intrinsic heterogeneity in DNA target selection and susceptibility to epigenetic DNA modification. This perspective invokes novel hypotheses in the regulation of ETS proteins in physiologic osmotic stress, their pioneering potential in heterochromatin, and the effects of passive and pharmacologic DNA demethylation on ETS regulation...
March 16, 2017: Transcription
https://www.readbyqxmd.com/read/28300856/halobetasol-propionate-lotion-0-05-provides-superior-hydration-compared-to-halobetasol-propionate-cream-0-05-in-a-double-blinded-study-of-occlusivity-and-hydration
#20
Gary Grove, Charles Zerweck, Tim Houser, Anthony Andrasfay, Bob Gauthier, Charles Holland, Daniel Piacquadio
BACKGROUND: This study measured skin hydration and occlusivity of two test products [halobetasol propionate lotion, 0.05% (HBP Lotion) and Ultravate® (halobetasol propionate) cream, 0.05% (HBP Cream)] at 2, 4, and 6 hours after application to skin test sites previously challenged by dry shaving, which was performed to compromise the integrity of the stratum corneum barrier. METHODS: Trans-epidermal water loss (TEWL), an indicator of skin barrier function, was measured using cyberDERM, inc...
February 1, 2017: Journal of Drugs in Dermatology: JDD
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