Read by QxMD icon Read

Newcastle disease virus

Panpan Zhao, Lingshuang Sun, Xiao Sun, Siwen Li, Wen Zhang, Laura A Pulscher, Hongliang Chai, Mingwei Xing
Newcastle disease virus (NDV) is a pathogen that most often infects poultry species. In investigating a 2014 outbreak of encephalitis and death among farmed mink (Mustela vison), we found pathological and later experimental evidence that NDV can infect and cause severe encephalitic and pneumonic disease in these animals. Our findings confirm the host range of NDV.
January 2017: Veterinary Microbiology
Maricarmen García
Infectious laryngotracheitis (ILT) is an economically important respiratory disease of poultry that affects the industry worldwide. Vaccination is the principal tool in the control of the disease. Two types of vaccines, live attenuated and recombinant viral vector, are commercially available. The first generation of GaHV-1 vaccines available since the early 1960's are live viruses, attenuated by continuous passages in cell culture or embryos. These vaccines significantly reduce mortalities and, in particular, the chicken embryo origin (CEO) vaccines have shown to limit outbreaks of the disease...
December 24, 2016: Veterinary Microbiology
Qingzhong Yu, Stephen Spatz, Yufeng Li, Jilong Yang, Wei Zhao, Zhenyu Zhang, Guoyuan Wen, Maricarmen Garcia, Laszlo Zsak
Newcastle disease virus (NDV) recombinants expressing the infectious laryngotracheitis virus (ILTV) glycoproteins B and D have previously been demonstrated to confer complete clinical protection against virulent ILTV and NDV challenges in naive chickens. We extended this study to assess whether maternally derived antibody (MDA) against NDV and ILTV would interfere with protection in vaccinated broiler chickens. Chickens with a mean NDV MDA hemagglutination inhibition (HI) titer of 6.4 (log2) and detectable ILTV neutralization (VN) antibodies at hatch were vaccinated with rLS/ILTV-gB or rLS/ILTV-gD at 1 or 10day of age (DOA) or on both days...
January 2, 2017: Vaccine
Qingsong Han, Xiaolong Gao, Pengpeng Wu, Sa Xiao, Xinglong Wang, Peng Liu, Lina Tong, Huafang Hao, Shuxia Zhang, Ruyi Dang, Zengqi Yang
Newcastle disease virus (NDV) infection causes serious problems in laying chickens, like reducing egg production, increasing rate of abnormal eggs in spite of strict vaccination in layer farms program. A new evaluation system is needed to show complete protection of the immunization in laying chickens based on the egg-laying performance, rather than clinical signs of the disease. In this study, laying chickens with different anti-NDV HI (hemagglutination-inhibition) antibody titer after vaccination were divided into different groups...
December 20, 2016: Research in Veterinary Science
Moushumee Das, Sachin Kumar
Despite the prevalence of Newcastle disease virus (NDV) outbreaks in India through the decades, there has been little genetic characterisation of the virulent strains circulating in Northeast India. In 2014, a poultry farm in the Kamrup district of Assam reported an ND outbreak. In this study, genetic analysis and clinicopathological tests showed the virulent nature of the isolate Kamrup. Based on prudent classification criteria, the virulent strain Kamrup was found to be most closely related to members of genotype XIII of class II NDV...
December 29, 2016: Archives of Virology
Guoyuan Wen, Min Wang, Honglin Wang, Lintao Li, Qingping Luo, Tengfei Zhang, Guofu Cheng, Huabin Shao
Here, we report the complete genome sequence of a virulent Newcastle disease virus (NDV) strain HN1007, isolated from diseased duck flocks in Henan, China, in 2010. The isolate has a genome length of 15,186 nucleotides, and was classified as a member of genotype III of class II.
December 29, 2016: Genome Announcements
Kiril M Dimitrov, Claudio L Afonso, Qingzhong Yu, Patti J Miller
Newcastle disease (ND) has been defined by the World Organisation for Animal Health as infection of poultry with virulent strains of Newcastle disease virus (NDV). Lesions affecting the neurological, gastrointestinal, respiratory, and reproductive systems are most often observed. The control of ND must include strict biosecurity that prevents virulent NDV from contacting poultry, and also proper administration of efficacious vaccines. When administered correctly to healthy birds, ND vaccines formulated with NDV of low virulence or viral-vectored vaccines that express the NDV fusion protein are able to prevent clinical disease and mortality in chickens upon infection with virulent NDV...
December 16, 2016: Veterinary Microbiology
Solveig Runge, Marita Olbert, Christiane Herden, Sara Malberg, Angela Römer-Oberdörfer, Peter Staeheli, Dennis Rubbenstroth
Avian bornaviruses are causative agents of proventricular dilatation disease (PDD), a chronic neurologic and often fatal disorder of psittacines including endangered species. To date no causative therapy or immunoprophylaxis is available. Our previous work has shown that viral vector vaccines can delay the course of homologous bornavirus challenge infections but failed to protect against PDD when persistent infection was not prevented. The goal of this study was to refine our avian bornavirus vaccination and infection model to better represent natural bornavirus infections in order to achieve full protection against a heterologous challenge infection...
December 22, 2016: Vaccine
D Kumar, T K S Chauhan, R K Agarwal, K Dhama, P P Goswami, A K Mariappan, A K Tiwari, B P Mishra
We applied a probe-based real-time loop-mediated isothermal amplification (Cy5-RTqLAMP) technique targeting the avian reovirus (ARV) S3 gene to develop a rapid, sensitive, and specific method for virus detection and quantification. This test specifically detected the presence of ARV, but not other viruses or bacteria present in clinical or artificially spiked samples, including Newcastle disease virus, infectious bursal disease virus, fowl adenovirus, Marek's disease virus, Escherichia coli, and Salmonella spp...
December 24, 2016: Archives of Virology
Yingjie Sun, Luna Dong, Shengqing Yu, Xiaoxu Wang, Hang Zheng, Pin Zhang, Chunchun Meng, Yuan Zhan, Lei Tan, Cuiping Song, Xusheng Qiu, Guijun Wang, Ying Liao, Chan Ding
Mammalian cells respond to various environmental stressors to form stress granules (SGs) by arresting cytoplasmic mRNA, protein translation element, and RNA binding proteins. Virus-induced SGs function in different ways, depending on the species of virus; however, the mechanism of SG regulation of virus replication is not well understood. In this study, Newcastle disease virus (NDV) triggered stable formation of bona fide SGs on HeLa cells through activating the protein kinase R (PKR)/eIF2α pathway. NDV-induced SGs contained classic SG markers T-cell internal antigen (TIA)-1, Ras GTPase-activating protein-binding protein (G3BP)-1, eukaryotic initiation factors, and small ribosomal subunit, which could be disassembled in the presence of cycloheximide...
December 23, 2016: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
Majid Esmaelizad, Vafa Mayahi, Maryam Pashaei, Hossein Goudarzi
Newcastle disease virus (NDV) is believed to be the cause of fatal poultry disease worldwide. The fusion (F) protein plays a key role in virus pathogenesis, and it is also used for Newcastle disease virus classification. In this study, we determined the complete coding sequence of the F gene in new velogenic NDV isolates with an intravenous pathogenicity index (IVPI) of 1.8 and a mean death time (MDT) of 72 or 48 h. Complete sequences of the F genes of new Iranian isolates were amplified and sequenced in both directions...
December 21, 2016: Archives of Virology
Ismaila Shittu, Tony M Joannis, Georgina N Odaibo, Olufemi D Olaleye
Over the years, Newcastle disease (ND) has defied all available control measures. The disease has remained at the forefront of infectious diseases afflicting poultry production after avian influenza. Despite the continuous global use of million doses of ND vaccine annually, the causative pathogen, avian paramyxovirus type 1 also known as Newcastle disease virus (NDV) has continued to evolve causing, even more, a threat not only to the unvaccinated but the vaccinated flocks inclusive. The disease has been well studied in the developed countries where the virus is found in circulation...
December 2016: Virusdisease
Alireza Seidavi, Mohammad Dadashbeiki, Mohammad-Hossein Alimohammadi-Saraei, René van den Hoven, Rita Payan-Carreira, Vito Laudadio, Vincenzo Tufarelli
The current study was conducted to analyse the effect of a mixture of probiotic cultures and enzymes (Probio Enzyme, XVET GmbH, Germany) on the immune response and weight of central lymphoid organs and liver in broilers. A total of 270 male chickens were randomly divided into nine groups, with three replicates of 10 birds each. Treatment groups were fed for either 22 or 42 days with different levels of Probio Enzyme 250, 500, 750 and 1000 g/ton, whereas the control group fed a basal diet without Probio Enzyme...
December 13, 2016: Environmental Science and Pollution Research International
Dilan A Satharasinghe, Kavitha Murulitharan, Sheau W Tan, Swee K Yeap, Muhammad Munir, Aini Ideris, Abdul R Omar
Newcastle disease virus (NDV) is a prototype member of avian paramyxovirus serotype 1 (APMV-1), which causes severe and contagious disease in the commercial poultry and wild birds. Despite extensive vaccination programs and other control measures, the disease remains endemic around the globe especially in Asia, Africa, and the Middle East. Being a single serotype, genotype II based vaccines remained most acceptable means of immunization. However, the evidence is emerging on failures of vaccines mainly due to evolving nature of the virus and higher genetic gaps between vaccine and field strains of APMV-1...
2016: Frontiers in Microbiology
Nathalie Turgeon, Marie-Josée Toulouse, Jim Ho, Dongqing Li, Caroline Duchaine
Little information is available regarding the effectiveness of air samplers to collect viruses and regarding the effects of sampling processes on viral integrity. The neuraminidase enzyme is present on the surface of viruses that are of agricultural and medical importance. It has been demonstrated that viruses carrying this enzyme can be detected using commercial substrates without having to process the sample by methods such as RNA extraction. This project aims at evaluating the effects of 3 aerosol-sampling devices on the neuraminidase enzyme activity of airborne viruses...
September 27, 2016: Canadian Journal of Microbiology
Wentao Fan, Yang Wang, Shenghua Wang, Ziqiang Cheng, Huijun Guo, Xiaona Zhao, Jianzhu Liu
In our research, the molecular evolutions of NDV F and HN genes were analyzed. The phylogenetic analyses of NDV sequences indicated that NDV could be divided into two genotypes: Class I (lentogenic strains) and Class II (velogenic or mesogenic strains). Each genotype possesses high gene homology. Furthermore, the selected pressure analysis showed that the dN/dS of velogenic, mesogenic NDV strains F gene was significantly high and the ω(dN/dS) is 1.1725>1. These results imply that mutations in velogenic, mesogenic NDV F gene are favored by positive natural selection and it has acted to diversify NDV virulence at the nucleotide and amino acid level...
December 7, 2016: Research in Veterinary Science
Tianyuan Zhang, Yunye Liu, Hui Wang, Xu Zhang, Shenglong Zhu, Pengfei Xu, Jiechao Yin, Guiping Ren, Jingli Liu, Deshan Li
Currently, there are two major bottleneck problems which seriously affect prevention of the Newcastle disease (ND): interference of maternal antibody on NDV vaccination and slow production of neutralization antibody. To overcome these problems, in present study, four rNDV vaccine strains expressing bio-adjuvants chIL2, chIL15, chGM-CSF or fliC gene were constructed and rescued using reverse genetics approach. The HI antibody titers of SPF birds immunized with rNDV reached to 5.5log2, 4.7log2, 6.5log2 and 5...
November 30, 2016: Veterinary Microbiology
Marsel R Kabilov, Tatyana Y Alikina, Kseniya S Yurchenko, Alexandra V Glushchenko, Konstantin V Gunbin, Alexander M Shestopalov, Natalya V Gubanova
Here, we report the complete genome sequences of two Newcastle disease virus (NDV) isolates, Adygea/duck/12/2008, from a wild duck in Russia, and Altai/pigeon/777/2010, from a pigeon in Russia. Based on comparative sequence analysis of the F gene, these strains were classified as NDV class II, genotypes VIId and VIb/2, respectively.
December 8, 2016: Genome Announcements
Yan Hu, Zhiqiang Duan, Xinqin Ji, Jiafu Zhao, Houqiang Xu, Shunlin Hu, Xiufan Liu
Here, we report the complete genome sequences of two Newcastle disease viruses, Sheldrake duck/China/Guizhou/01/2016 and Sheldrake duck/China/Guizhou/02/2016, isolated from Sansui Sheldrake ducks in Guizhou Province, China. The genome of the isolates is 15,198 nucleotides in length. Phylogenetic analysis revealed that the isolates are clustered into subgenotype 1b in class I.
December 8, 2016: Genome Announcements
Reta D Abdi, Kassaw Amssalu Tadesse, Olana Merera, Yilkal Asfaw, Eseyas Gelaye, Marta Yami, Teshale Sori
No abstract text is available yet for this article.
December 8, 2016: BMC Veterinary Research
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"