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https://www.readbyqxmd.com/read/29473880/assessment-and-treatment-of-pediatric-sleep-problems-knowledge-skills-attitudes-and-practices-in-a-group-of-community-child-psychiatrists
#1
Ali Anwar, Michael D Yingling, Alicia Zhang, Ujjwal Ramtekkar, Ginger E Nicol
As part of a university-based quality improvement project, we aimed to evaluate child psychiatrists' knowledge, skills, attitudes, and practices regarding assessment and treatment of pediatric sleep problems. We developed a nine-question survey of knowledge, skills, attitudes, and practices regarding assessing for and treating sleep complaints in pediatric patients, and administered this survey to child psychiatrists in training and in practice in the state of Missouri. Respondents reported sleep hygiene as the first-line treatment strategy, followed by the use of supplements or over-the-counter remedies...
February 23, 2018: Medical Sciences: Open Access Journal
https://www.readbyqxmd.com/read/29467818/knowledge-transfer-a-worldwide-challenge-in-child-mental-health-a-recommendation-to-the-readership-of-capmh-concerning-the-revised-version-of-the-iacapap-textbook-of-child-and-adolescent-mental-health
#2
Anna T Maier, Rebecca C Brown, Joerg M Fegert
Background: Transfer of knowledge is an important issue throughout all scientific disciplines, especially in the medical and psycho-social field. The issue of worldwide knowledge transfer in child mental health is one of the aims and goals of the journal Child and Adolescent Psychiatry and Mental Health (CAPMH). The demand for mental health training is high worldwide, and especially in low- to lower-middle income countries, where inadequate access to knowledge resources in the field of child and adolescent mental health (CAMH) is prevalent...
2018: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/29466090/enhanced-external-counterpulsation-and-short-term-recovery-from-high-intensity-interval-training
#3
Pedro L Valenzuela, Guillermo Sánchez-Martínez, Elaia Torrentegi, Zigor Montalvo, Alejandro Lucia, Pedro de la Villa
PURPOSE: The use of enhanced external counter-pulsation (EECP) as a recovery strategy has increased in recent years owing to its benefits in the clinical setting. However, its claimed effectiveness for the enhancement of exercise recovery has not been analyzed in athletes. The aim of this study was to determine the effectiveness of EECP on short-term recovery after a fatiguing exercise bout. METHODS: 12 elite junior triathletes (16 ± 2 years) participated in this cross-over counterbalanced study...
February 21, 2018: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29460655/clinical-evidence-for-washing-and-cleansers-in-acne-vulgaris-a-systematic-review
#4
Thomas Stringer, Arielle Nagler, Seth J Orlow, Vikash S Oza
PURPOSE: Washing and over-the-counter cleansers are common interventions in acne vulgaris (AV), but the clinical evidence for their benefit is poorly understood. This systematic review presents clinical studies of washing and cleanser efficacy in acne vulgaris to guide treatment recommendations of dermatologists. MATERIALS AND METHODS: We surveyed English-language articles indexed in MEDLINE (1951-March 2017) and EMBASE (1974-March 2017). Articles were required to be prospective studies of a single over-the-counter cleanser or washing intervention in AV with an objective AV outcome measurement published in a peer-reviewed journal...
February 20, 2018: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29460083/kidney-function-and-use-of-nonsteroidal-anti-inflammatory-drugs-among-elderly-people-a-cross-sectional-study-on-potential-hazards-for-an-at-risk-population
#5
Sara Modig, Sölve Elmståhl
Background Renal elimination normally decreases with age. Nonsteroidal antiinflammatory drugs (NSAIDs) carry a risk of additional kidney damage. Objective The aims of this study were to assess the prevalence of NSAIDs in the elderly (aged ≥ 65) population in Sweden, explore reasons for any possible differences in the level of use and assess their kidney functions. Setting Data were obtained from the cohort study Good Aging in Skåne, Sweden. Patients aged 65 or more were included. Methods Medication lists were collected as well as variables such as cognition and education levels...
February 19, 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29457141/extrahepatic-toxicity-of-acetaminophen-critical-evaluation-of-the-evidence-and-proposed-mechanisms
#6
Stefanie Kennon-McGill, Mitchell R McGill
Research on acetaminophen (APAP) toxicity over the last several decades has focused on the pathophysiology of liver injury, but increasing attention is being paid to other known and possible adverse effects. It has been known for decades that APAP causes acute kidney injury, but confusion exists regarding prevalence, and the mechanisms have not been well investigated. More recently, a number of experimental, clinical and epidemiological studies have reported evidence for pulmonary, endocrine, neurological and neurodevelopmental toxicity, but the quality of evidence from those studies varies...
January 15, 2018: Journal of Clinical and Translational Research
https://www.readbyqxmd.com/read/29456156/a-multilayer-coil-in-type-i-counter-current-chromatography
#7
Yi Yang, Jiao Yang, Chen Fang, Dongyu Gu, Ying Ma, Yoichiro Ito
In the present study, a novel model of type-I counter-current chromatography was developed to simplify the separation column manufacture and extend its application ranges. In this system, a multilayer coil was used as the separation column of type-I counter-current chromatography for the first time. The chromatographic performance of this apparatus was evaluated in terms of retention of the stationary phase (Sf), theoretical plate (N) and peak resolution (Rs) using dipeptides and DNP-amino acids as test samples with two classic solvent systems composed of 1-butanol-acetic acid-water (4:1:5, v/v) (BAW) and hexane-ethyl acetate-methanol-0...
February 13, 2018: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29451468/health-care-resource-use-and-costs-pre-and-post-treatment-initiation-with-linaclotide-retrospective-analyses-of-a-u-s-insured-population
#8
Douglas Ca Taylor, Jessica L Abel, Tim Bancroft, Paul Buzinec, Alyssa Goolsby Hunter, Robyn T Carson, Carolyn Martin
As expected, pharmacy costs increased with the introduction of this new treatment in a market dominated by over-the-counter and generic treatments. On the other hand, outpatient GI-related and irritable bowel disease health care resource use and costs substantially decreased among commercial and Medicare patients following linaclotide treatment initiation.
February 2018: Managed Care
https://www.readbyqxmd.com/read/29450196/recruitment-and-lessons-learned-from-a-community-based-intervention-program-the-learning-families-project-in-hong-kong
#9
Joanna T W Chu, Alice Wan, Sunita M Stewart, Kwok Tung Ng, Tai Hing Lam, Sophia S Chan
Background: Recruitment is central to any research project, and recruitment itself should be well documented and researched. We describe our recruitment efforts for a community-based research project-entitled the Learning Families Project-conducted in Hong Kong. Methods: In collaboration with community stakeholders, residents from a public housing estate were recruited to participate in family programs aimed at enhancing family well-being. Various recruitment strategies were employed including the distribution of 19,200 leaflets, 688 posters, a banner, a kick-off ceremony, 10 promotion activities, 1,000 direct calls, word of mouth, 51 mobile counters, and 10 door-to-door visits...
2018: Frontiers in Public Health
https://www.readbyqxmd.com/read/29449651/beyond-streptococcus-mutans-clinical-implications-of-the-evolving-dental-caries-aetiological-paradigms-and-its-associated-microbiome
#10
N Philip, B Suneja, L Walsh
Aetiological concepts of dental caries have evolved over the years from being considered as a disease initiated by nonspecific microorganisms, to being regarded as an 'infectious' disease caused by specific bacteria, to the current paradigms that emphasise a 'mixed bacterial-ecological approach' as being responsible for lesion initiation and pathogenesis. These aetiological paradigms are not just intellectual concepts but have important implications on how clinicians manage this age-old disease in the twenty-first century...
February 16, 2018: British Dental Journal
https://www.readbyqxmd.com/read/29449377/haploid-embryonic-stem-cells-can-be-enriched-and-maintained-by-simple-filtration
#11
Chao Qu, Meng Yan, Suming Yang, Lingbo Wang, Qi Yin, Yuan Liu, Yeguang Chen, Jinsong Li
Haploid mammalian embryonic stem cells (haESCs) serve as a powerful tool for genetic analyses at both cellular and organismal levels. However, spontaneous diploidization of haESCs limits their use in these analyses. Addition of small molecules to culture medium to control the cell cycle can slow down diploidization, but cell-sorting methods such as FACS are still required to enrich haploid cells for long-term maintenance in vitro. Here, acting on our observation that haploid and diploidized cells differ in diameter, we developed a simplified filtration method to enrich haploid cells from cultured haESCs...
February 15, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29449296/gp-and-parent-dissonance-about-the-assessment-and-treatment-of-childhood-eczema-in-primary-care-a-qualitative-study
#12
Kingsley Powell, Emma Le Roux, Jonathan Banks, Matthew J Ridd
OBJECTIVES: To compare parents' and clinicians' perspectives on the assessment and treatment of children with eczema in primary care. DESIGN: Qualitative interview study with purposive and snowball sampling and thematic analysis. SETTING: 14 general practices in the UK. PARTICIPANTS: 11 parents of children with eczema and 15 general practitioners (GPs) took part in semistructured individual interviews. RESULTS: We identified several areas of dissonance between parents and GPs...
February 15, 2018: BMJ Open
https://www.readbyqxmd.com/read/29446932/separation-of-xylene-isomers-through-multiple-metal-site-interactions-in-metal-organic-frameworks
#13
Miguel I Gonzalez, Matthew T Kapelewski, Eric D Bloch, Phillip J Milner, Douglas A Reed, Matthew R Hudson, Jarad A Mason, Gokhan Barin, Craig M Brown, Jeffrey R Long
Purification of the C 8 alkylaromatics o-xylene, m-xylene, p-xylene, and ethylbenzene remains among the most challenging industrial separations, owing to the similar shapes, boiling points, and polarities of these molecules. Herein, we report the evaluation of the metal-organic frameworks Co 2 (dobdc) (dobdc 4- = 2,5-dioxido-1,4-benzenedicarboxylate) and Co 2 (m-dobdc) (m-dobdc 4- = 4,6-dioxido-1,3-benzenedicarboxylate) for the sepa-ration of xylene isomers using single-component adsorption isotherms and multi-component breakthrough measurements...
February 15, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29446457/toward-a-multifactorial-model-of-expertise-beyond-born-versus-made
#14
David Z Hambrick, Alexander P Burgoyne, Brooke N Macnamara, Fredrik Ullén
The debate over the origins of individual differences in expertise has raged for over a century in psychology. The "nature" view holds that expertise reflects "innate talent"-that is, genetically determined abilities. The "nurture" view counters that, if talent even exists, its effects on ultimate performance are negligible. While no scientist takes seriously a strict nature-only view of expertise, the nurture view has gained tremendous popularity over the past several decades...
February 15, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29435794/emergency-contraceptive-pills-ecp-knowledge-attitudes-and-practices-among-women-working-in-the-entertainment-industry-and-men-in-the-trucking-industry-bhutan
#15
Deki Pem, Tshewang Nidup, Ugyen Wangdi, Dorji Pelzom, Ali Mirzazadeh, Willi McFarland
Emergency contraceptive pills (ECP) were recently made available over the counter in Bhutan. We evaluated knowledge, attitudes, and practices concerning ECP in 2 populations at risk for HIV and STI (sexually transmitted infections): entertainment women (drayang) and male truck drivers and helpers (truckers). Of 179 drayang and 437 truckers intercepted at venues, 73.7 and 21.1%, respectively, had heard of ECP; 47.0% of drayang had used them. Their concerns about ECP use included harm to the body, impact on future pregnancy, side effects, and HIV/STI risk...
February 12, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29435278/enhanced-analgesic-effects-of-nefopam-in-combination-with-acetaminophen-in-rodents
#16
Qian Li, Quankun Zhuang, Yaru Gu, Cailing Dai, Xiaoxiao Gao, Xiaomin Wang, Huimin Wen, Xin Li, Yuyang Zhang
Nefopam, an analgesic drug, effectively elicits antinociception in the majority of noxious and thermal models in rodents. Acetaminophen is among the most commonly used analgesic and antipyretic drugs worldwide, either on prescription or over the counter. The present study aimed to investigate the analgesic activity of nefopam combined with acetaminophen, which was expected to maximize the potency of analgesia and decrease the dose of nefopam required. Three series of experiments, namely acetic acid-induced writhing tests in mice, hot plate tests in mice and tail flick tests in rats, were used to evaluate the analgesic effect...
February 2018: Biomedical Reports
https://www.readbyqxmd.com/read/29432091/influenza-a-h7n9-virus-antibody-responses-in-survivors-1-year-after-infection-china-2017
#17
Mai-Juan Ma, Cheng Liu, Meng-Na Wu, Teng Zhao, Guo-Lin Wang, Yang Yang, Hong-Jing Gu, Peng-Wei Cui, Yuan-Yuan Pang, Ya-Yun Tan, Hui Hang, Bao Lin, Jiang-Chun Qin, Li-Qun Fang, Wu-Chun Cao, Li-Ling Cheng
Avian influenza A(H7N9) virus has caused 5 epidemic waves in China since its emergence in 2013. We investigated the dynamic changes of antibody response to this virus over 1 year postinfection in 25 patients in Suzhou City, Jiangsu Province, China, who had laboratory-confirmed infections during the fifth epidemic wave, Oct 1, 2016-February 14, 2017. Most survivors had relatively robust antibody responses that decreased but remained detectable at 1 year. Antibody response was variable; several survivors had low or undetectable antibody titers...
April 17, 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29431977/hemorrhoids-diagnosis-and-treatment-options
#18
Timothy Mott, Kelly Latimer, Chad Edwards
Many Americans between 45 and 65 years of age experience hemorrhoids. Hemorrhoidal size, thrombosis, and location (i.e., proximal or distal to the dentate line) determine the extent of pain or discomfort. The history and physical examination must assess for risk factors and clinical signs indicating more concerning disease processes. Internal hemorrhoids are traditionally graded from I to IV based on the extent of prolapse. Other factors such as degree of discomfort, bleeding, comorbidities, and patient preference should help determine the order in which treatments are pursued...
February 1, 2018: American Family Physician
https://www.readbyqxmd.com/read/29431371/palpitations-evaluation-in-the-primary-care-setting
#19
Randell K Wexler, Adam Pleister, Subha V Raman
Palpitations are a common problem in the ambulatory primary care setting, and cardiac causes are the most concerning etiology. Psychiatric illness, adverse effects of prescription and over-the-counter medications, and substance use should also be considered. Distinguishing cardiac from noncardiac causes is important because of the risk of sudden death in those with an underlying cardiac etiology. A thorough history and physical examination, followed by targeted diagnostic testing, can distinguish cardiac conditions from other causes of palpitations...
December 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/29428578/treatment-practices-of-households-and-antibiotic-dispensing-in-medicine-outlets-in-developing-countries-the-case-of-ghana
#20
Mary-Anne Ahiabu, Pascal Magnussen, Ib Christian Bygbjerg, Britt Pinkowski Tersbøl
INTRODUCTION: Antibiotic resistance, associated with inappropriate drug use, is a global public health threat. The pharmaceutical sectors in developing countries are poorly regulated leading to antibiotic sales and use without a prescription. The study documents the treatment of acute illnesses in households and the antibiotic dispensing practices of medicine sales outlets in Eastern region, Ghana. METHOD: Twice-weekly illness recall visits were made to 12 households in three rural communities over eight consecutive weeks...
February 7, 2018: Research in Social & Administrative Pharmacy: RSAP
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