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https://www.readbyqxmd.com/read/29235853/general-synthetic-route-toward-highly-dispersed-ultrafine-pd-au-alloy-nanoparticles-enabled-by-imidazolium-based-organic-polymers
#1
Yaqiong Gong, Hong Zhong, Wenhui Liu, Bingbing Zhang, Shuangqi Hu, Ruihu Wang
Bimetallic Pd-Au nanoparticles (NPs) usually show superior catalytic performances over their single component counterparts, the general and facile synthesis of subnanometer-scaled Pd-Au NPs still remains a great challenge, especially for electronegative ultrafine bimetallic NPs. Here, we develop an anion-exchange strategy for the preparation of ultrafine Pd-Au alloy NPs. Simple treatment of main-chain imidazolium-based organic polymer (IOP) with HAuCl4 and Na2PdCl4, and followed by reduction with NaBH4 generated Pd-Au alloy NPs (Pd-Au/IOP)...
December 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29235174/big-data-and-medicine-a-big-deal
#2
Viktor Mayer-Schönberger, Erik Ingelsson
Big Data promises huge benefits for medical research. Looking beyond superficial increases in the amount of data collected, we identify three key areas where Big Data differs from conventional analyses of data samples: (1) data is captured more comprehensively relative to the phenomenon under study; this reduces some bias but surfaces important tradeoffs, such as between data quantity and data quality; (2) data is often analyzed using machine learning tools, such as neural networks rather than conventional statistical methods resulting in systems that over time capture insights implicit in data, but remain black boxes, rarely revealing causal connections; and (3) the purpose of the analyses of data is no longer simply answering existing questions, but hinting at novel ones and generating promising new hypotheses...
December 13, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/29234207/over-the-counter-products-in-line-for-user-fee-program
#3
Stephen Barlas
Over-the-counter products in line for user fee program.
December 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29233395/knowledge-attitudes-and-beliefs-regarding-human-immunodeficiency-virus-and-in-home-testing-among-a-regional-sample-of-student-pharmacists
#4
Alvina Tran, Autumn L Stewart, Jordan R Covvey
INTRODUCTION: Pharmacists identify the importance of education on human immunodeficiency virus (HIV); however, research suggests deficits in knowledge regarding recommendations and testing devices. With proper training, student pharmacists can play an important role in counseling patients on the importance of HIV testing and providing instruction on in-home testing. The objective of the study was to assess student pharmacists' knowledge, attitudes and beliefs of HIV and the use of an in-home, over-the-counter HIV testing device...
November 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29233276/comparison-of-long-term-knowledge-retention-in-lecture-based-versus-flipped-team-based-learning-course-delivery
#5
Catherine Taglieri, David Schnee, Lana Dvorkin Camiel, Kathy Zaiken, Amee Mistry, Stefanie Nigro, Gary Tataronis, Dhiren Patel, Susan Jacobson, Jennifer Goldman
OBJECTIVES: To determine whether team based learning (TBL) is superior to traditional lecture -based learning in confidence and knowledge retention one year later. DESIGN: A survey was administered 17 months after a completion of a required over-the-counter /self-care (OTC) course to two different cohorts of students. The survey assessed confidence and knowledge related to OTC topics. The lecture group had a traditional lecture based classroom experience; the intervention group experienced a TBL format throughout the entire course...
May 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29232433/over-the-counter-topical-musculoskeletal-pain-relievers-used-with-a-heat-source-a-dangerous-combination
#6
Shayna C Rivard, Megan A Brelsford, Neil F Gibbs
No abstract text is available yet for this article.
November 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/29229227/the-importance-of-the-circadian-system-sleep-for-bone-health
#7
Christine M Swanson, Wendy M Kohrt, Orfeu M Buxton, Carol A Everson, Kenneth P Wright, Eric S Orwoll, Steven A Shea
Adequate sleep timed appropriately during the circadian night is important for numerous biological processes and systems. New evidence suggests that both sleep timing and duration may be important for optimal bone health as well. This review examines the diurnal variation of bone turnover markers (BTMs) and the importance of circadian clock genes in regulating bone mass. In addition, this review explores the evidence for a link between shift work (and its associated disturbances in sleep duration/quality and circadian alignment) and alterations in bone metabolism and bone health...
December 8, 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29228409/short-term-effects-of-combined-high-intensity-strength-and-sprint-interval-training-on-anthropometric-characteristics-and-physical-performance-of-elite-team-handball-players
#8
Souhail Hermassi, Mohamed Souhail Chelly, Georg Fieseler, Thomas Bartels, Stephan Schulze, Karl-Stefan Delank, Roy J Shepard, René Schwesig
Muscular strength and speed are critical physical factors in determining the technical and tactical skills of elite team handball players. This study thus investigated the effect of high-intensity muscular strength and sprint interval training (SIT) on lower limb explosive performance and anthropometric characteristics in 22 male handball athletes aged 20.2 ± 0.1 years. A training group (TG, n = 12) and a control group (CG, n = 10) were followed over 8 weeks parallel to regular handball training...
December 2017: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
https://www.readbyqxmd.com/read/29227521/pediatric-poisonings-the-risk-of-over-the-counter-pharmaceuticals
#9
Elizabeth Quaal Hines
Every week in the United States, 56% of children younger than age 18 years and 82% of adults take at least one medication. Nonprescription medications, including acetaminophen and ibuprofen, are among the most commonly used pharmaceuticals across all age groups. Use of nonprescription medications, traditionally available over-the-counter, has become ubiquitous. Unfortunately, with such abundant use there is an associated risk for therapeutic misuse, intentional misuse, and even abuse. [Pediatr Ann. 2017;46(12):e454-e458...
December 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/29226023/evaluating-the-whitening-and-microstructural-effects-of-a-novel-whitening-strip-on-porcelain-and-composite-dental-materials
#10
Thair Takesh, Anik Sargsyan, Matthew Lee, Afarin Anbarani, Jessica Ho, Petra Wilder-Smith
Aims: The aim of this project was to evaluate the effects of 2 different whitening strips on color, microstructure and roughness of tea stained porcelain and composite surfaces. Methods: 54 porcelain and 72 composite chips served as samples for timed application of over-the-counter (OTC) test or control dental whitening strips. Chips were divided randomly into three groups of 18 porcelain and 24 composite chips each. Of these groups, 1 porcelain and 1 composite set served as controls...
August 2017: Dentistry: Current Research
https://www.readbyqxmd.com/read/29224920/-cognitive-doping-in-students-a-chim-er-ical-way-to-get-full-head
#11
Louise Carton, Nicolas Cabé, Olivier Ménard, Sylvie Deheul, Anne-Sylvie Caous, David Devos, Olivier Cottencin, Régis Bordet
For students, the requirements for memorization, increased performance and peer competition may encourage cognitive doping behaviors. We aimed to describe recent practices and the benefit/risk ratio of such behavior to discuss the different issues. The prevalence of cognitive doping among students was 1.3% to 33% according to the studies, depending on the country concerned and the definition of cognitive doping used. The therapeutic classes most frequently cited as being diverted were psychostimulants and nootropics (methylphenidate, modafinil, piracetam), corticosteroids, sedative drugs and beta-blockers...
November 22, 2017: Thérapie
https://www.readbyqxmd.com/read/29224770/pain-control-following-tonsillectomy-in-children-a-survey-of-patients
#12
Philip R Persino, Lena Saleh, David L Walner
OBJECTIVE: This prospective study aimed to survey pediatric patients and their parents after tonsillectomy to assess their pain management utilization and satisfaction. INTRODUCTION: Tonsillectomy is the second most common surgical procedure performed in pediatric patients. Postoperative recovery is often associated with high levels of pain and severe functional limitations. There is currently no consensus on pain control regimens. Additionally, a recent FDA Black Box Warning on narcotic use has caused more uncertainty in appropriate pain control regimens...
December 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29224633/over-the-counter-medicines-and-diabetes-care
#13
Jeff Taylor
OBJECTIVES: People with diabetes turn to over-the-counter (OTC) medicines for many ailments. The focus of this brief review is the impact common OTC medicines might have on this group of patients. METHODS: Three types of OTC medicines were selected as most deserving of attention: 3 herbal agents, nonsteroidal anti-inflammatory drugs (NSAIDs) and cough/cold products. Existing literature was used to determine precautions that might be in order. RESULTS: Herbal/natural agents with the potential to impact blood sugar have been identified in various reports...
December 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29223966/advancing-point-of-care-diagnostics-for-the-control-and-prevention-of-stis-the-way-forward
#14
Igor Toskin, Karel Blondeel, Rosanna W Peeling, Carolyn Deal, James Kiarie
WHO recognises the global impact of sexually transmitted infections (STIs) on global public health and individual sexual and reproductive health and well-being. As a component of the WHO Global Health Sector Strategy for the control and prevention of STIs, there has been a growing recognition of the importance of integrating point-of-care tests (POCTs) into overall strategic planning. The process of integrating STI POCTs, in addition to providing a definitive diagnosis and appropriate treatment in a single visit, also includes innovative delivery options, such as on-site delivery, community-based testing (including screening), as well as self-testing at home after purchase of a test online or over-the-counter...
December 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29223349/the-effect-of-cerebellar-transcranial-direct-current-stimulation-on-a-throwing-task-depends-on-individual-level-of-task-performance
#15
Nobuaki Mizuguchi, Takashi Katayama, Kazuyuki Kanosue
The effect of cerebellar transcranial direct current stimulation (tDCS) on motor performance remains controversial. Some studies suggest that the effect of tDCS depends upon task-difficulty and individual level of task performance. Here, we investigated whether the effect of cerebellar tDCS on the motor performance depends upon the individual's level of performance. Twenty-four naïve participants practiced dart throwing while receiving 2mA-cerebellar tDCS for 20min under three stimulus conditions (anodal-, cathodal-, and sham-tDCS) on separate days with a double-blind, counter-balanced cross-over design...
December 6, 2017: Neuroscience
https://www.readbyqxmd.com/read/29221834/emotion-and-sex-of-facial-stimuli-modulate-conditional-automaticity-in-behavioral-and-neuronal-interference-in-healthy-men
#16
Nils Kohn, Guillén Fernández
Our surrounding provides a host of sensory input, which we cannot fully process without streamlining and automatic processing. Levels of automaticity differ for different cognitive and affective processes. Situational and contextual interactions between cognitive and affective processes in turn influence the level of automaticity. Automaticity can be measured by interference in Stroop tasks. We applied an emotional version of the Stroop task to investigate how stress as a contextual factor influences the affective valence-dependent level of automaticity...
December 5, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/29218681/management-strategies-to-facilitate-optimal-outcomes-for-patients-treated-with-delayed-release-dimethyl-fumarate
#17
Lori Mayer, Mary Kay Fink, Carrie Sammarco, Lisa Laing
Delayed-release dimethyl fumarate is an oral disease-modifying therapy that has demonstrated significant efficacy in adults with relapsing-remitting multiple sclerosis. Incidences of flushing and gastrointestinal adverse events are common in the first month after delayed-release dimethyl fumarate initiation. Our objective was to propose mitigation strategies for adverse events related to initiation of delayed-release dimethyl fumarate in the treatment of patients with multiple sclerosis. Studies of individually developed mitigation strategies and chart reviews were evaluated...
December 7, 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/29217682/overexpression-of-the-histone-dimethyltransferase-g9a-in-nucleus-accumbens-shell-increases-cocaine-self-administration-stress-induced-reinstatement-and-anxiety
#18
Ethan M Anderson, Erin B Larson, Daniel Guzman, Anne Marie Wissman, Rachael L Neve, Eric J Nestler, David W Self
Repeated exposure to cocaine induces lasting epigenetic changes in neurons that promote the development and persistence of addiction. One epigenetic alteration involves reductions in levels of the histone dimethyltransferase, G9a, in nucleus accumbens (NAc) after chronic cocaine administration. This reduction in G9a may enhance cocaine reward since overexpressing G9a in the NAc decreases cocaine-conditioned place preference. Thus, we hypothesized that HSV-mediated G9a overexpression in the NAc shell (NAcSh) would attenuate cocaine self-administration and cocaine-seeking behavior...
December 7, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29211054/barriers-and-facilitators-for-information-exchange-during-over-the-counter-consultations-in-community-pharmacy-a-focus-group-study
#19
Liza J Seubert, Kerry Whitelaw, Fabienne Boeni, Laetitia Hattingh, Margaret C Watson, Rhonda M Clifford
Consumers are confident managing minor ailments through self-care, often self-medicating from a range of over-the-counter (OTC) medicines available from community pharmacies. To minimise risks, pharmacy personnel endeavour to engage in a consultation when consumers present with OTC enquiries however they find consumers resistant. The aim was to determine stakeholder perspectives regarding barriers and facilitators for information exchange during OTC consultations in community pharmacies and to understand the elicited themes in behavioural terms...
December 6, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/29207687/variation-in-morphometry-of-vastus-medialis-muscle
#20
Hina B Rajput, Sangeeta J Rajani, Vasant H Vaniya
Introduction: The Vastus Medialis (VM) muscle divides into two parts, proximal Vastus Medialis Longus (VML) and distal Vastus Medialis Obliquus (VMO). The VMO originates from the tendon of adductor magnus and insert into the medial border of patella and these fibers are nearly horizontal. It exerts medial force vector to counter the lateral force vector of Vastus Lateralis (VL) hence the VM presents a biomechanical advantage over the VL. The functional importance of VML and VMO is well explained but the anatomical evidence of separate identity of VMO is lacking...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
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