keyword
https://read.qxmd.com/read/38535707/childbirth-preparation-knowledge-of-the-use-of-non-pharmacological-pain-relief-methods-during-childbirth-in-tshwane-district-south-africa-a-cross-sectional-study
#1
JOURNAL ARTICLE
Seemole Eniffer Matabane, Maurine Rofhiwa Musie, Mavis Fhumulani Mulaudzi
Effective management of labour pain is an essential aspect of care provided to women during childbirth. The aim of this study was to assess pregnant women's knowledge of using non-pharmacological pain relief methods during childbirth. Methods: This quantitative descriptive cross-sectional study was conducted at four hospitals in the Tshwane District of South Africa. The sample consisted of 384 pregnant women. Results: The results show that ( n = 200, 52.1%) pregnant women lack knowledge regarding non-pharmacological pain relief methods, while a minority ( n = 101, 26...
December 21, 2023: Nursing Reports
https://read.qxmd.com/read/38535109/atypical-progeria-primarily-manifesting-as-premature-cardiac-valvular-disease-segregates-with-lmna-gene-variants
#2
Hoi W Wu, Ivo P Van de Peppel, Julie W Rutten, J Wouter Jukema, Emmelien Aten, Ingrid M Jazet, Tamara T Koopmann, Daniela Q C M Barge-Schaapveld, Nina Ajmone Marsan
Mutations in the LMNA -gene can cause a variety of 'laminopathies'. These laminopathies are associated with a range of phenotypes, including disorders affecting the adipose tissue, peripheral nerves, the heart, such as dilated cardiomyopathy and conduction system abnormalities, and less commonly, progeroid disorders. This case series describes two families in which two novel LMNA-gene variants were identified, and who presented with an atypical progeroid phenotype with primarily premature aortic and mitral valve stenosis...
March 5, 2024: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/38535069/correlation-between-structural-and-functional-changes-in-patients-with-raised-intraocular-pressure-due-to-graves-orbitopathy
#3
JOURNAL ARTICLE
Freja Bagatin, Ante Prpić, Jelena Škunca Herman, Ognjen Zrinšćak, Renata Iveković, Zoran Vatavuk
This study explores the complication of secondary intraocular pressure (IOP) elevation and consequent glaucoma development in Graves' orbitopathy (GO), an autoimmune disorder associated with hyperthyroidism. Utilizing Octopus 900 visual field testing and optical coherence tomography (OCT), the research established correlations between functional and structural changes in optic nerve regions in patients with GO and patients with GO with elevated IOP (GO IOP) groups. A comparison with primary open-angle glaucoma (POAG) was conducted in a cohort of 182 subjects...
March 20, 2024: Diagnostics
https://read.qxmd.com/read/38534785/cellular-organelle-related-transcriptomic-profile-abnormalities-in-neuronopathic-types-of-mucopolysaccharidosis-a-comparison-with-other-neurodegenerative-diseases
#4
JOURNAL ARTICLE
Karolina Wiśniewska, Lidia Gaffke, Magdalena Żabińska, Grzegorz Węgrzyn, Karolina Pierzynowska
Mucopolysaccharidoses (MPS) are a group of diseases caused by mutations in genes encoding lysosomal enzymes that catalyze reactions of glycosaminoglycan (GAG) degradation. As a result, GAGs accumulate in lysosomes, impairing the proper functioning of entire cells and tissues. There are 14 types/subtypes of MPS, which are differentiated by the kind(s) of accumulated GAG(s) and the type of a non-functional lysosomal enzyme. Some of these types (severe forms of MPS types I and II, MPS III, and MPS VII) are characterized by extensive central nervous system disorders...
March 21, 2024: Current Issues in Molecular Biology
https://read.qxmd.com/read/38533894/long-term-intake-of-thermo-induced-oxidized-oil-results-in-anxiety-like-and-depression-like-behaviors-involvement-of-microglia-and-astrocytes
#5
JOURNAL ARTICLE
Meishan Lu, Jiachen Shi, Xue Li, Yanjun Liu, Yuanfa Liu
Frequent consumption of fried foods has been strongly associated with a higher risk of anxiety and depression, particularly among young individuals. The existing evidence has indicated that acrylamide produced from starchy foods at high temperatures can induce anxious behavior. However, there is limited research on the nerve damage caused by thermo-induced oxidized oil (TIOO). In this study, we conducted behavioral tests on mice and found that prolonged consumption of TIOO led to significant anxiety behavior and a tendency toward depression...
March 27, 2024: Food & Function
https://read.qxmd.com/read/38533833/trans-carotid-artery-revascularization-versus-carotid-endarterectomy-in-patients-with-carotid-artery-disease-systematic-review-and-meta-analysis-of-30-day-outcomes
#6
REVIEW
Georgios Loufopoulos, Vasiliki Manaki, Panagiotis Tasoudis, Nina-Rafailia Karela, Christophe Sénéchaud, Argirios Giannopoulos, Kiriakos Ktenidis, Konstantinos Spanos
This systematic review and meta-analysis compared trans-carotid artery revascularization (TCAR) as an alternative approach to carotid endarterectomy (CEA) in patients with carotid artery disease. An electronic search was conducted using PubMed, Scopus, and Cochrane databases including comparative studies with patients who underwent either TCAR or CEA. This meta-analysis is according to the recommendations of the PRISMA statement. Eight studies met our eligibility criteria, incorporating 7,606 and 7,048 patients in the TCAR and CEA groups, respectively...
March 27, 2024: Angiology
https://read.qxmd.com/read/38533721/new-developments-in-cosmetic-applications-of-electromagnetic-fields-client-and-occupational-hazard-assessment
#7
REVIEW
Rianne Stam
Energy-based devices are used to improve features of appearance for aesthetic reasons while avoiding more invasive methods. Examples of treatment targets are the reduction of wrinkles, sagging, unwanted skin lesions, body hair and excess fatty tissue, and the enhancement of muscle tissue. One treatment modality is the use of electromagnetic fields (EMF, 0‒300 GHz). The present work aims to give an up-to-date survey of cosmetic applications of EMF for professional use with an assessment of client and worker exposure and possible adverse effects...
March 27, 2024: Bioelectromagnetics
https://read.qxmd.com/read/38533631/spatio-temporal-image-based-encoded-atlases-for-eeg-emotion-recognition
#8
JOURNAL ARTICLE
Danilo Avola, Luigi Cinque, Angelo Di Mambro, Alessio Fagioli, Marco Raoul Marini, Daniele Pannone, Bruno Fanini, Gian Luca Foresti
Emotion recognition plays an essential role in human-human interaction since it is a key to understanding the emotional states and reactions of human beings when they are subject to events and engagements in everyday life. Moving towards human-computer interaction, the study of emotions becomes fundamental because it is at the basis of the design of advanced systems to support a broad spectrum of application areas, including forensic, rehabilitative, educational, and many others. An effective method for discriminating emotions is based on ElectroEncephaloGraphy (EEG) data analysis, which is used as input for classification systems...
May 2024: International Journal of Neural Systems
https://read.qxmd.com/read/38533199/study-on-the-clinical-and-electrophysiological-characteristics-of-nerve-function-in-myasthenia-gravis-patients-in-vietnam
#9
JOURNAL ARTICLE
Tho Kieu Anh Pham, Phuong Van Pham, Tung Dinh Le, Binh Thanh Nguyen, Trung Kien Nguyen, Tam Thai Thanh Tran, Sam Phan Hai Nguyen, Minh Van Le
BACKGROUND: In Vietnam, there is limited research on the role of nerve conduction in myasthenia gravis and its association with clinical features. OBJECTIVE: This study aims to describe the electrophysiological features in patients with myasthenia gravis. METHODS: This descriptive study was conducted from September 2019 to December 2021. The study included 33 myasthenia gravis patients who sought medical consultation or received inpatient treatment during this period...
2024: SAGE Open Medicine
https://read.qxmd.com/read/38533175/the-comparative-efficacy-of-palmitoylethanolamide-pea-with-the-combination-of-pregabalin-and-nortriptyline-on-post-extraction-trigeminal-neuropathy-by-using-magnetic-resonance-mr-neurography-a-randomized-clinical-trial
#10
JOURNAL ARTICLE
Amlendu Shekhar, Adit Srivastava, Nimisha Verma, Ashish Verma, T P Chaturvedi
Aim The aim of this randomized clinical trial is to compare the efficacy of palmitoylethanolamide (PEA) with the combination of pregabalin and nortriptyline in treating post-extraction trigeminal neuropathy using magnetic resonance neurography (MRN). Methods The present prospective, randomized controlled trial was conducted on 60 patients (20 in each group). In group I (positive control group), a combination of 75 mg of pregabalin and 10 mg of nortriptyline was administered once daily for the duration of 12 weeks...
February 2024: Curēus
https://read.qxmd.com/read/38533170/keto-clarity-a-comprehensive-systematic-review-exploring-the-efficacy-safety-and-mechanisms-of-ketogenic-diet-in-pediatric-epilepsy
#11
REVIEW
Youmna Faheem, Amisha Jaiswal, Kainaat Shergill, Kusalik Boppana, Naiela E Almansouri, Saloni Bakkannavar, Ann Kashmer Yu
Epilepsy, a widespread neurological disorder characterized by recurrent seizures, affects millions globally, with a significant impact on the pediatric population. Antiepileptic drugs (AEDs) constitute the primary treatment; however, drug-resistant epilepsy (DRE), especially in children, poses a therapeutic challenge. Alternative interventions, such as surgery, vagus nerve stimulation, and the ketogenic diet (KD), have been explored. This systematic review aims to investigate various types of KDs, their distinctions, their effectiveness, and their safety concerning the reduction of seizure frequency, achieving seizure freedom, and the occurrence of adverse events...
February 2024: Curēus
https://read.qxmd.com/read/38532858/anthranilic-acid-a-gpr109a-agonist-and-schizophrenia
#12
JOURNAL ARTICLE
Gregory Oxenkrug, Brent Forester
INTRODUCTION: Limited clinical efficiency of current medications warrants search for new antipsychotic agents. Deorphanized G-protein coupled receptor (GPR)109A has not attracted much of attention of schizophrenia researchers. We analyzed literature and our data on endogenous agonists of GPR109A, beta-hydroxybutyrate (BHB), anthranilic (AA), butyric (BA), and nicotinic (NA) acids, in individuals with schizophrenia. DATA: Sex specific differences: plasma AA levels were 27% higher in female than in male patients and correlated with PANSS before 6 weeks of antipsychotics treatment ( r  = ...
2024: International Journal of Tryptophan Research: IJTR
https://read.qxmd.com/read/38532638/factors-affecting-the-topography-of-nitrous-oxide-induced-neurological-complications
#13
JOURNAL ARTICLE
Eva Sole Cruz, Etienne Fortanier, Frederic Hilezian, Adil Maarouf, Clémence Boutière, Sarah Demortière, Audrey Rico, Emilien Delmont, Jean Pelletier, Shahram Attarian, Bertrand Audoin
BACKGROUND: The factors underlying the topography of nitrous oxide (N2 O)-induced neurological complications are unknown. METHODS: We included all consecutive patients admitted to the university hospital of Marseille for N2 O-induced neurological complications in a prospective observational study. Patients underwent neurological examination, spinal cord magnetic resonance imaging, and nerve conduction studies within the first 4 weeks after admission. RESULTS: In total, 61 patients were included: 45% with myeloneuropathy, 34% with isolated myelopathy, and 21% with isolated neuropathy...
March 26, 2024: European Journal of Neurology
https://read.qxmd.com/read/38532327/dermoscopic-features-of-nails-in-leprosy-patients-in-a-tertiary-referral-hospital-in-west-java-indonesia
#14
JOURNAL ARTICLE
Hendra Gunawan, Namira Bening Nurani
INTRODUCTION: Leprosy is a chronic granulomatous infectious disease, mainly affecting the skin and peripheral nerves, caused by the obligate intracellular bacteria Mycobacterium leprae. The disease has been discussed in several review articles in recent research, but as far as we know, only a few have addressed the effects of leprosy on nails, especially those who examine the dermoscopic features of nails in leprosy patients. PURPOSES: We aimed to document nail changes in leprosy patients and identify any particular findings through dermoscopic examination...
March 26, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38532189/encephalitis-like-episodes-with-cortical-edema-and-enhancement-in-patients-with-neuronal-intranuclear-inclusion-disease
#15
JOURNAL ARTICLE
Yu Shen, Kaiyan Jiang, Hanlin Liang, Ying Xiong, Ziwei Song, Bo Wang, Min Zhu, Yusen Qiu, Dandan Tan, Chengsi Wu, Jianwen Deng, Zhaoxia Wang, Daojun Hong
OBJECTIVES: Neuronal intranuclear inclusion disease (NIID) exhibited significant clinical heterogeneities. However, the clinical features, radiographic changes, and prognosis of patients with encephalitis-like NIID have yet to be systematically elucidated. METHODS: Clinical data including medical history, physical examination, and laboratory examinations were collected and analyzed. Skin and sural nerve biopsies were conducted on the patient. Repeat-primed PCR (RP-PCR) and fluorescence amplicon length PCR (AL-PCR) were used to detect the expansion of CGG repeat...
March 26, 2024: Neurological Sciences
https://read.qxmd.com/read/38532142/efgartigimod-in-the-treatment-of-guillain-barr%C3%A3-syndrome
#16
JOURNAL ARTICLE
Huiqiu Zhang, Jing Ma, Yingna Feng, Hui Ma, Dan Liu, Xiaomin Pang, Xueli Chang, Rongjuan Zhao, Juan Wang, Junhong Guo, Wei Zhang
BACKGROUND: Guillain-Barré Syndrome (GBS) is caused by immunoglobulin G (IgG) autoantibodies. Efgartigimod, a human IgG antibody Fc fragment that acts as a natural ligand for the FcRn, can increase IgG degradation, which thus may be a promising therapeutic drug for GBS. CASE PRESENTATION: The two patients presented with postinfectious and acute flaccid paralysis. On admission, they were bedridden. Nerve conduction studies indicated peripheral neuropathy. GBS was suspected and they are treated with two doses of efgartigimod (10 mg/kg) within 5 days...
March 26, 2024: Journal of Neurology
https://read.qxmd.com/read/38531122/enhanced-deep-unrolling-networks-for-snapshot-compressive-hyperspectral-imaging
#17
JOURNAL ARTICLE
Xinran Qin, Yuhui Quan, Hui Ji
Snapshot compressive hyperspectral imaging necessitates the reconstruction of a complete hyperspectral image from its compressive snapshot measurement, presenting a challenging inverse problem. This paper proposes an enhanced deep unrolling neural network, called EDUNet, to tackle this problem. The EDUNet is constructed via the deep unrolling of a proximal gradient descent algorithm and introduces two innovative modules for gradient-driven update and proximal mapping reflectivity. The gradient-driven update module leverages a memory-assistant descent approach inspired by momentum-based acceleration techniques, for enhancing the unrolled reconstruction process and improving convergence...
March 19, 2024: Neural Networks: the Official Journal of the International Neural Network Society
https://read.qxmd.com/read/38530974/conductive-and-enhanced-mechanical-strength-of-mo-2-ti-2-c-3-mxene-based-hydrogel-promotes-neurogenesis-and-bone-regeneration-in-bone-defect-repair
#18
JOURNAL ARTICLE
Hongyu Wang, Yu-Ching Hsu, Chune Wang, Xiao Xiao, Zhengbin Yuan, Yong Zhu, Dazhi Yang
Bone defects are common with increasing high-energy fractures, tumor bone invasion, and implantation revision surgery. Bone is an electroactive tissue that has electromechanical interaction with collogen, osteoblasts, and osteoclasts. Hydrogel provides morphological plasticity and extracellular matrix (ECM) 3D structures for cell survival, and is widely used as a bone engineering material. However, the hydrogels have poor mechanical intensity and lack of cell adhesion, slow gelation time, and limited conductivity...
March 26, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38530452/mri-evaluation-of-cranial-nerve-abnormalities-and-extraocular-muscle-fibrosis-in-duane-retraction-syndrome-and-congenital-extraocular-muscle-fibrosis
#19
JOURNAL ARTICLE
Tiantian Yang, Xiaotong Li, Kailei Wang, Quan Zhang, Rui Hao, Wei Zhang
PURPOSE: To investigate the alterations in extraocular muscles (EOMs) by magnetic resonance imaging (MRI) among patients diagnosed with Duane retraction yndrome (DRS) and congenital fibrosis of the extraocular muscles (CFEOM), who present with various cranial nerve anomalies in an attempt to enhance the clinical diagnostic process. METHODS: A case-control study was conducted to evaluate 27 patients with DRS and 14 patients with CFEOM. All patients underwent MRI scans of the brainstem and orbital examination...
March 26, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38529872/-neuropathy-in-n-hexane-poisoning
#20
JOURNAL ARTICLE
E S Druzhinina, A A Kozyreva, R T Bembeeva, A S Kozlovsky, V E Sokolova, I V Isaev, A G Narbutov, N N Zavadenko, O A Tikhonova
N-Hexane is a solvent widely used in manufacturing as a cleaner, degreaser and component of rubber cement. Chronic exposure to n -hexane either through contact with unprotected skin or inhalation can lead to the development of clinical symptoms and electrophysiological changes similar to those of inflammatory demyelinating polyneuropathy which requires careful differential diagnosis. This article presents three cases of severe predominantly motor polyneuropathy with demyelinating features in 15- and 16-year-old adolescents...
2024: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
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