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https://www.readbyqxmd.com/read/29036213/the-value-of-real-time-continuous-glucose-monitoring-in-premature-infants-of-diabetic-mothers
#1
Hean-Pat Saw, Nai-Wei Yao, Cheng-Di Chiu, Jia-Yuh Chen
To determine the feasibility of using a real-time continuous glucose monitoring system (RTGMS) in intensive care units, our study focus on preterm infants with diabetic mothers owing to their high risk of blood sugar abnormalities. Thirty preterm babies (M = 15 and F = 15; ≤ 36 week gestation age) were studied from within 72 hours of delivery. These babies were admitted to the newborn intensive care and were further categorized into groups based on whether their mothers with or without diabetic mellitus. Blood sugar levels were monitored by both RTGMS and the traditional intermittent arterial line (A-Line) glucose method...
2017: PloS One
https://www.readbyqxmd.com/read/29034019/hybrid-repair-of-an-abdominal-aortic-aneurysm-debranching-with-endovascular-aneurysm-repair-in-a-patient-with-horseshoe-kidney
#2
Keiwa Kin, Hiroshi Takano, Takaya Nakagawa, Yukitoshi Shirakawa
Abdominal aortic aneurysm (AAA) with associated horseshoe kidney (HSK) poses a technical challenge when performing conventional open surgical repair because of possible complications including renal infarction, neuralgia, and collecting system disruption. Endovascular aortic repair (EVAR) is considered the first-line treatment for this pathology, allowing for aneurysm repair without isthmus bisection. However, whether to sacrifice commonly presenting aberrant renal arteries during EVAR is a point of controversy...
March 24, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29033290/nonvascularized-cartilage-grafts-versus-vascularized-cartilage-flaps-comparison-of-cartilage-quality-6%C3%A2-months-after-transfer-and-isolated-from-surrounding%C3%A2-bone-ingrowth
#3
James P Higgins, Farzad Borumandi, Heinz K Bürger, Mehmet Emre Benlidayı, Anna Vasilyeva, Leman Sencar, Sait Polat, Alexander J Gaggl
PURPOSE: Subchondral perfusion of osteochondral grafts has been shown to be important in preventing long-term cartilage degeneration. In carpal reconstruction, subchondral perfusion from the graft bed is limited. This study's purpose was to compare the histological characteristics of cartilage in osteochondral grafts supported by synovial imbibition alone to cartilage of vascularized osteochondral flaps that have both synovial and vascular pedicle perfusion. METHODS: Two adjacent osteochondral segments were harvested on the medial femoral trochlea in domestic 6- to 8-month-old pigs...
October 12, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29032219/emergency-extracranial-intracranial-bypass-to-revascularize-salvageable-brain-tissue-in-acute-ischemic-stroke-patients
#4
Jan-Karl Burkhardt, Sebastian Winklhofer, Jorn Fierstra, Susanne Wegener, Giuseppe Esposito, Andreas Luft, Oliver Bozinov, Luca Regli
INTRODUCTION: To present an algorithm based on clinical and radiological factors including MR perfusion/diffusion mismatch (MR-PDM) for the indication of urgent cerebral bypass in patients with acute ischemic stroke METHODS: Analysis of clinical and radiological data on eight consecutive patients undergoing urgent cerebral revascularization for acute ischemic stroke due to occlusion of the internal carotid or middle cerebral artery between 2012 and 2015. All patients were either not eligible or failed first line treatment with emergent endovascular revascularization...
October 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29032217/preoperative-prediction-of-the-necessity-for-anterior-clinoidectomy-during-microsurgical-clipping-of-ruptured-posterior-communicating-artery-aneurysms
#5
Tomoya Kamide, Jan-Karl Burkhardt, Halima Tabani, Michael Safaee, Michael T Lawton
BACKGROUND: Although most posterior communicating artery (PCoA) aneurysms can be clipped easily with excellent results, some require anterior clinoidectomy for safe and complete clipping. OBJECTIVE: To review our microsurgical series of ruptured PCoA aneurysms and identify the preoperative predictors for anterior clinoidectomy during microsurgical clipping for PCoA aneurysms METHODS: Results from microsurgical clipping of 104 patients with ruptured PCoA aneurysms were retrospectively reviewed...
October 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29030929/infection-prevention-in-pediatric-anesthesia-practice
#6
REVIEW
Lizabeth D Martin, Michael Kallile, Siri Kanmanthreddy, Danielle M Zerr
Healthcare-associated infections are an important source of morbidity and mortality in pediatric patients. Anesthesiologists have a unique role in infection prevention. Hand hygiene and anesthesia workspace decontamination decrease infection rates in surgical patients. Standard protocols exist for insertion and handling of central lines, arterial lines, and regional procedures, which should be strictly adhered to in order to prevent infectious complications. Temperature control and timely administration of antibiotics contribute to the prevention of surgical site infections...
November 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/29029777/-management-of-high-risk-pulmonary-embolism-with-pulmonary-artery-trunk-mobile-thrombus
#7
A Rougé, L Perriollat, M Abdellaoui, B Faurie, J Monségu
The presence of a right intraventricular thrombus is a marker of severity of pulmonary embolism (PE), and is associated with high mortality. We report the case of a young patient with a PE postoperative of patellar tendon surgery. The cardiac echocardiography at its admission revealed a voluminous mobile thrombus of 1.7cm diameter located on the pulmonary trunk. Systemic thrombolysis was performed because of respiratory deterioration allowing a rapid disappearance of the thrombus and recovery. Our case emphasizes the value of a complete ultrasound analysis centered on the pulmonary trunk in the case of intermediate-risk PE...
October 10, 2017: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29029237/cpap-does-not-reduce-inflammatory-biomarkers-in-patients-with-coronary-artery-disease-and-nonsleepy-obstructive-sleep-apnea-a-randomized-controlled-trial
#8
Erik Thunström, Helena Glantz, Tülay Yucel-Lindberg, Kristin Lindberg, Mustafa Saygin, Yüksel Peker
Objectives: Obstructive sleep apnea (OSA) and enhanced vascular inflammation coexist in patients with coronary artery disease (CAD). Continuous positive airway pressure (CPAP) is first-line treatment for OSA with daytime sleepiness. This analysis of data from the RICCADSA trial investigated the effects of CPAP on inflammatory markers in patients with CAD and nonsleepy OSA. Methods: This single-center, randomized, controlled, open-label trial enrolled consecutive revascularized patients with nonsleepy OSA (apnea-hypopnea index >15/h; Epworth Sleepiness Scale score <10)...
October 5, 2017: Sleep
https://www.readbyqxmd.com/read/29025710/opposing-actions-of-akt-protein-kinase-b-isoforms-in-vascular-smooth-muscle-injury-and-therapeutic-response
#9
Yu Jin, Yi Xie, Allison C Ostriker, Xinbo Zhang, Renjing Liu, Monica Y Lee, Kristen L Leslie, Waiho Tang, Jing Du, Seung Hee Lee, Yingdi Wang, William C Sessa, John Hwa, Jun Yu, Kathleen A Martin
OBJECTIVE: Drug-eluting stent delivery of mTORC1 (mammalian target of rapamycin complex 1) inhibitors is highly effective in preventing intimal hyperplasia after coronary revascularization, but adverse effects limit their use for systemic vascular disease. Understanding the mechanism of action may lead to new treatment strategies. We have shown that rapamycin promotes vascular smooth muscle cell differentiation in an AKT2-dependent manner in vitro. Here, we investigate the roles of AKT (protein kinase B) isoforms in intimal hyperplasia...
October 12, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/29024947/human-trophoblast-derived-hydrogen-sulfide-stimulates-placental-artery-endothelial-cell-angiogenesis
#10
Dongbao Chen, Lin Feng, Jennifer K Hodges, Thomas J Lechuga, Honghai Zhang
Endogenous hydrogen sulfide (H2S), mainly synthesized by cystathionine β-synthase (CBS) and cystathionineγ-lyase (CTH), has been implicated in regulating placental angiogenesis; however, the underlying mechanisms are unknown. This study was to test a hypothesis that trophoblasts synthesize H2S to promote placental angiogenesis. Human choriocarcinoma-derived BeWo cells expressed both CBS and CTH proteins while the first trimester villous trophoblast-originated HTR-8/SVneo cells expressed CTH protein only. The H2S producing ability of BeWo cells was significantly inhibited by either inhibitors of CBS (CHH) or CTH (BCA) and that in HTR-8/SVneo cells was inhibited by CHH only...
August 28, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/29021615/a-new-pedicled-internal-mammary-osteomyocutaneous-chimeric-flap-pimoc-for-salvage-head-and-neck-reconstruction-anatomic-study-and-clinical-application
#11
Guilherme C Barreiro, Chelsea C Snider, Flavio H F Galvão, Rachel R Baptista, Kiril E Kasai, Daniel M Dos Anjos, Marcus C Ferreira
Well-vascularized composite tissue offers improved outcomes for complex head and neck reconstruction. Patients with vessel-depleted necks and failed reconstructions require alternative reconstructive options. We describe a pedicled internal mammary artery osteomyocutaneous chimeric flap (PIMOC) for salvage head and neck reconstruction. Bilateral dissections of 35 fresh cadavers were performed to study individual tissue components and vascular pedicles to develop the PIMOC technique. The flap was then utilized in a series of patients with vessel-depleted neck anatomy...
October 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29019017/leptospirosis-associated-catastrophic-respiratory-failure-supported-by-extracorporeal-membrane-oxygenation
#12
Tamara Cantwell, Andrés Ferre, Nicolette Van Sint Jan, Rodrigo Blamey, Jorge Dreyse, Cristian Baeza, Rodrigo Diaz, Tomás Regueira
A previously healthy, 39-year-old obese farmer, arrived hypotensive and tachycardic, with fever, myalgia, headache, abdominal pain, diarrhea, and progressive dyspnea. Ten days before symptoms onset, he was in direct contact with mice and working in a contaminated drain. Patient laboratory showed acute kidney injury and thrombocytopenia. Chest X-ray exhibited bilateral diffuse interstitial infiltrates. First-line empirical antibiotics were started and influenza discarded. Patient evolved with severe respiratory failure, associated with hemoptysis, and rapidly severe hemodynamic compromise...
October 10, 2017: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29018535/left-ventricular-longitudinal-systolic-function-analysed-by-2d-speckle-tracking-echocardiography-in-heart-failure-with-preserved-ejection-fraction-a-meta-analysis
#13
Daniel Armando Morris, Xin-Xin Ma, Evgeny Belyavskiy, Radhakrishnan Aravind Kumar, Martin Kropf, Robin Kraft, Athanasios Frydas, Engin Osmanoglou, Esteban Marquez, Erwan Donal, Frank Edelmann, Carsten Tschöpe, Burkert Pieske, Elisabeth Pieske-Kraigher
BACKGROUND: The purpose of this meta-analysis was to confirm if the global longitudinal systolic function of the left ventricle (LV) is altered in patients with heart failure with preserved ejection fraction (HFpEF). METHODS: We searched in different databases (Medline, Embase and Cochrane) studies that analysed LV global longitudinal systolic strain (GLS) in patients with HFpEF and in controls (such as healthy subjects or asymptomatic patients with arterial hypertension, diabetes mellitus or coronary artery disease)...
2017: Open Heart
https://www.readbyqxmd.com/read/29018081/platelet-interaction-with-activated-endothelium-mechanistic-insights-from-microfluidics
#14
Daniëlle M Coenen, Tom G Mastenbroek, Judith M E M Cosemans
Traditionally, in vitro flow chamber experiments and in vivo arterial thrombosis studies have been proven to be of vital importance to elucidate the mechanisms of platelet thrombus formation after vessel wall injury. In recent years, it has become clear that platelets also act as modulators of inflammatory processes, such as atherosclerosis. A key element herein is the complex crosstalk between platelets, the coagulation system, leukocytes and the activated endothelium. This review provides insight into the platelet-endothelial interface, based on in vitro flow chamber studies and cross referenced with in vivo thrombosis studies...
October 10, 2017: Blood
https://www.readbyqxmd.com/read/29018024/circulatory-dynamics-during-pulmonary-vein-isolation-using-the-second-generation-cryoballoon
#15
Takatsugu Kajiyama, Shinsuke Miyazaki, Tomonori Watanabe, Kazuya Yamao, Shigeki Kusa, Miyako Igarashi, Hiroaki Nakamura, Hitoshi Hachiya, Yoshito Iesaka
BACKGROUND: Circulatory dynamics change during pulmonary vein (PV) isolation using cryoballoons. This study sought to investigate the circulatory dynamics during cryoballoon-based PV isolation procedures and the contributing factors. METHODS AND RESULTS: This study retrospectively included 35 atrial fibrillation patients who underwent PV isolation with 28-mm second-generation cryoballoons and single 3-minute freeze techniques. Blood pressures were continuously monitored via arterial lines...
October 10, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29016510/comparative-effectiveness-of-uterine-leiomyoma-procedures-using-a-large-insurance-claims-database
#16
Bijan J Borah, Xiaoxi Yao, Shannon K Laughlin-Tommaso, Herbert C Heien, Elizabeth A Stewart
OBJECTIVE: To compare risk of reintervention, long-term clinical outcomes, and health care utilization among women who have bulk symptoms from leiomyoma and who underwent the following procedures: hysterectomy, myomectomy, uterine artery embolization, and magnetic resonance-guided, focused ultrasound surgery. METHODS: This was a retrospective analysis of administrative claims from a large U.S. commercial insurance database. Women aged 18-54 years undergoing any of the previously mentioned leiomyoma procedures between 2000 and 2013 were included...
October 6, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28993755/extracranial-internal-carotid-artery-tortuosity-and-body-mass-index
#17
Hai-Feng Wang, Da-Ming Wang, Jun-Jie Wang, Li-Jun Wang, Jun Lu, Peng Qi, Shen Hu, Xi-Meng Yang, Kun-Peng Chen
BACKGROUND: Extracranial internal carotid artery (eICA) tortuosity may trigger cerebral ischemia, and body mass index (BMI) is a measure of body mass based on height and weight. The main purpose of this study is to determine the influence of BMI on the tortuosity of eICA. METHODS: A total of 926 carotid artery angiograms were performed in 513 patients, of which 116 cases and matched controls were selected. Arterial tortuosity was defined as simple tortuosity, kinking, or coiling...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28993230/the-importance-of-blood-platelet-lipid-signaling-in-thrombosis-and-in-sepsis
#18
REVIEW
Fanny Vardon Bounes, Abdulrahman Mujalli, Claire Cenac, Sonia Severin, Pauline Le Faouder, Gaëtan Chicanne, Frédérique Gaits-Iacovoni, Vincent Minville, Marie-Pierre Gratacap, Bernard Payrastre
Blood platelets are the first line of defense against hemorrhages and are also strongly involved in the processes of arterial thrombosis, a leading cause of death worldwide. Besides their well-established roles in hemostasis, vascular wall repair and thrombosis, platelets are now recognized as important players in other processes such as inflammation, healing, lymphangiogenesis, neoangiogenesis or cancer. Evidence is accumulating they are key effector cells in immune and inflammatory responses to host infection...
September 29, 2017: Advances in Biological Regulation
https://www.readbyqxmd.com/read/28992881/cost-effectiveness-analysis-of-transcatheter-arterial-chemoembolization-with-or-without-sorafenib-for-the-treatment-of-unresectable-hepatocellular-carcinoma
#19
Rong-Ce Zhao, Jing Zhou, Yong-Gang Wei, Fei Liu, Ke-Fei Chen, Qiu Li, Bo Li
BACKGROUND: Transcatheter arterial chemoembolization (TACE) and TACE in combination with sorafenib (TACE-sorafenib) have shown a significant survival benefit for the treatment of unresectable hepatocellular carcinoma (HCC). Adopting either as a first-line therapy carries major cost and resource implications. The objective of this study was to estimate the relative cost-effectiveness of TACE against TACE-sorafenib for unresectable HCC using a decision analytic model. METHODS: A Markov cohort model was developed to compare TACE and TACE-sorafenib...
October 15, 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28986709/uterine-artery-pseudoaneurysm-in-the-setting-of-deep-endometriosis-an-uncommon-cause-of-hemoperitoneum-in-pregnancy
#20
Zoe Feld, Tami Rowen, Andrew Callen, Ruth Goldstein, Liina Poder
Uterine, ovarian, and placental pathologies are among the differential considerations for a pregnant woman presenting with abdominal and pelvic pain. Imaging plays a key role in the initial work-up of these patients. Sonography is often the first line test; however, evaluation of pelvic pathology can be limited in the gravid state, especially in mid- or late-term pregnancy. We present a case of a pregnant woman who came to the emergency room at 25 weeks with acute abdominal and pelvic pain. Both ultrasound and MR imaging findings revealed intraperitoneal hemorrhage, initially of unknown origin, as well as endometriomas and deep endometriosis...
October 6, 2017: Emergency Radiology
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