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Philip steig

Kurt Reifenberg, Hans-Anton Lehr, Michael Torzewski, Gisela Steige, Elena Wiese, Ines Küpper, Christoph Becker, Sibylle Ott, Petra Nusser, Ken-Ichi Yamamura, Gerd Rechtsteiner, Tobias Warger, Andrea Pautz, Hartmut Kleinert, Albrecht Schmidt, Burkert Pieske, Philip Wenzel, Thomas Münzel, Jürgen Löhler
Chronic heart failure is associated with an activation of the immune system characterized among other factors by the cardiac synthesis and serum expression of proinflammatory cytokines. There is unequivocal clinical and experimental evidence that the cytokine tumor necrosis factor-alpha is involved in the development of chronic heart failure, but a putative cardiotoxic potential of the proinflammatory cytokine interferon (IFN)-gamma remains primarily unknown. To investigate this issue we analyzed the cardiac phenotype of SAP-IFN-gamma transgenic mice, which constitutively express IFN-gamma in their livers and hence exhibit high circulating serum levels of this cytokine...
August 2007: American Journal of Pathology
Kuo H Chao, Howard A Riina, Linda Heier, Philip E Steig, Y Pierre Gobin
Congenital or nonatherosclerotic dolichoectasia is a rare condition; its etiology, natural history, and indications and technique of treatment are not yet clarified. During a workup for recent headaches and left-sided paresthesia in a 48 year-old female patient, brain MR imaging and cerebral angiography showed a large dolichoectasia of the P2 segment of the right posterior cerebral artery (PCA). The patient passed endovascular testing for occlusion of P2 with both balloon test occlusion and selective amytal testing...
November 2004: AJNR. American Journal of Neuroradiology
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