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https://www.readbyqxmd.com/read/29775958/a-systematic-review-of-community-based-interventions-to-improve-oral-chronic-disease-medication-regimen-adherence-among-individuals-with-substance-use-disorder
#1
REVIEW
Karen M Clements, Tasmina Hydery, Mark A Tesell, Bonnie C Greenwood, Michael C Angelini
BACKGROUND: Poor medication adherence has been shown to cause medical complications, death, and increased healthcare costs and may be of particular importance in patients with substance use disorder (SUD). Concerns regarding adherence in this population may influence a healthcare provider's decision to prescribe a medication requiring high adherence. Guidance defining best practices that promote adherence among individuals with SUD is lacking. METHODS: A review of English articles in Medline and PsycINFO databases, published between October 1, 1994 and October 31, 2017, was conducted in order to identify studies of interventions intended to improve adherence to oral chronic disease medication regimens among patients with SUD...
May 1, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29775876/childhood-abuse-and-depression-in-adulthood-the-mediating-role-of-allostatic-load
#2
Sandra Scheuer, Nicole Wiggert, Tanja Maria Brückl, Yvonne Awaloff, Manfred Uhr, Susanne Lucae, Stefan Kloiber, Florian Holsboer, Marcus Ising, Frank H Wilhelm
BACKGROUND: Traumatic experiences during childhood are considered a major risk factor for depression in adulthood. Childhood trauma may induce physiological dysregulation with long-term effects of increased allostatic load until adulthood, which may lead to depression. Thus, our aim was to investigate whether allostatic load - which represents a multi-system measure of physiological dysregulation - mediates the association between childhood trauma and adult depression. METHODS: The study sample consisted of 324 depressed inpatients participating in the Munich Antidepressant Response Signature (MARS) project and 261 mentally healthy control participants...
April 22, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29775793/analysis-of-dna-methylation-at-specific-loci-in-stool-samples-detects-colorectal-cancer-and-high-grade-dysplasia-in-patients-with-inflammatory-bowel-disease
#3
John B Kisiel, Pasquale Klepp, Hatim T Allawi, William R Taylor, Maria Giakoumopoulos, Tamara Sander, Tracy C Yab, Bjorn A Moum, Graham P Lidgard, Stephan Brackmann, Douglas W Mahoney, Arne Roseth, David A Ahlquist
BACKGROUND & AIMS: Patients with inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), are at increased risk for colorectal cancer (CRC). Analyses of DNA methylation patterns in stool samples have been reported to detect CRC in patients with IBD. We sought to validate these findings in larger cohorts and assess the accuracy of analysis of DNA methylation patterns in stool for detection of CRC and high-grade dysplasia (HGD) normalized to methylation level at ZDHHC1...
May 15, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29775697/prodrome-and-non-prodrome-phenotypes-of-bladder-pain-syndrome-interstitial-cystitis
#4
John W Warren, Ningbo Jian, Lisa Gallicchio, David Wu, Daniel J Clauw
OBJECTIVE: To test the hypothesis that risk factors for BPS/IC in women differ between those with and without the BPS/IC prodrome. METHODS: Incident cases of BPS/IC and healthy controls were recruited nationally. More than half the BPS/IC cases reported subsyndromal urinary symptoms for decades before onset of BPS/IC and were identified as having the prodrome. Risk factors for BPS/IC were examined separately for cases with and without the prodrome using a set of matched controls...
May 15, 2018: Urology
https://www.readbyqxmd.com/read/29775680/assessing-the-effects-of-daily-commuting-in-two-patch-dengue-dynamics-a-case-study-of-cali-colombia
#5
Edwin Barrios, Sunmi Lee, Olga Vasilieva
There are many infectious diseases that can be spread by daily commuting of people and dengue fever is one of them. The absence of vaccine and irregularities in ongoing vector control programs make this disease the most frequent and persistent in many tropical and subtropical regions of the world. This paper targets to access the effects of daily commuting on dengue transmission dynamics by using a deterministic two-patch model fitted to observed data gathered in Cali, Colombia where dengue fever is highly persistent and exhibits endemo-epidemic patterns...
May 15, 2018: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/29775675/associations-between-angiotensinogen-m235t-polymorphisms-and-the-risk-of-diabetic-nephropathy-a-meta-analysis
#6
Bo Zhou, Min Wen, Ling Mi, Cu-Jiao Hu, Yi Zhang, Jian-Tar Wang, Lei Tang
AIMS: The aim of the present study was to clarify the potential relationship of angiotensinogen (AGT) M235T polymorphism and diabetic nephropathy (DN) risk. METHODS: Comprehensive electronic search in Pubmed, Web of Science, EBSCO, Embase, the Cochrane Library and China National Knowledge Infrastructure (CNKI) to find original articles about the association between AGT M235T polymorphism and DN risk published before 27 September 2017. Literature quality assessment was performed with the Newcastle-Ottawa Scale...
May 15, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29775618/association-between-klotho-expression-and-malignancies-risk-and-progression-a-meta-analysis
#7
Song Mao, Xiaopeng Wang, Liangxia Wu, Dou Zang, Wenjing Shi
BACKGROUND: We assessed the association between tissue klotho protein expression and the risk and progression of malignancies. METHODS: We searched the electronic databases for the studies regarding the relationship between tissue klotho protein expression and risk/progression of malignancies through January 2018. We calculated the pooled odds ratios (ORs) and corresponding 95% confidence intervals (CIs) to evaluate the impact of tissue klotho protein expression on malignancies...
May 15, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29775482/risk-of-venous-thromboembolism-in-association-with-factor-v-leiden-in-cancer-patients-the-edith-case-control-study
#8
Adeline Heraudeau, Aurélien Delluc, Mickaël Le Henaff, Karine Lacut, Christophe Leroyer, Benoit Desrues, Francis Couturaud, Cécile Tromeur
BACKGROUND: Cancer and factor V Leiden mutation are both risk factors for venous thromboembolism (VTE). Cancer critically increases the thrombotic risk whereas Factor V Leiden is the most common pro-thrombotic mutation. The impact of the factor V Leiden on the risk of VTE in cancer patients remains uncertain. OBJECTIVE: To assess the impact of factor V Leiden mutation in cancer-associated thrombosis. METHODS: The EDITH hospital-based case-control study enrolled 182 patients with cancer and VTE as well as 182 control patients with cancer, matched for gender, age and cancer location, between 2000 and 2012, in the University Hospital of Brest...
2018: PloS One
https://www.readbyqxmd.com/read/29775426/impact-of-a-native-streptomyces-flavovirens-from-mushroom-compost-on-green-mold-control-and-yield-of-agaricus-bisporus
#9
Ljiljana Šantrić, Ivana Potočnik, Ljiljana Radivojević, Jelena Gajić Umiljendić, Emil Rekanović, Bojan Duduk, Svetlana Milijašević-Marčić
Thirty-five actinobacterial isolates, obtained from button mushroom (Agaricus bisporus) substrates (i.e., compost in different phases of composting, black peat or casing layer) in Serbia in 2014-2016 were tested in vitro against the causal agents of green mold in cultivated mushroom. Out of six most promising isolates, A06 induced 42.4% in vitro growth inhibition of Trichoderma harzianum T54, and 27.6% inhibition of T. aggressivum f. europaeum T77. The novel strain A06 was identified as Streptomyces flavovirens based on macroscopic and cultural characteristics and 16S rDNA sequence and used in mushroom growing room experiments...
May 18, 2018: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
https://www.readbyqxmd.com/read/29775379/decision-to-return-to-sport-participation-after-anterior-cruciate-ligament-reconstruction-part-ii-self-reported-and-functional-performance-outcomes
#10
Jennifer L Werner, Julie P Burland, Carl G Mattacola, Jenny Toonstra, Robert A English, Jennifer S Howard
CONTEXT:   Anterior cruciate ligament (ACL) reconstruction (ACLR) is the most commonly used method for helping athletes regain function and return to preinjury activity levels after ACL injury. Outcomes after ACLR have suggested that athletes return to a level of function that would support a return to sport participation; however, in a recent meta-analysis, pooled return rates were only 55%. It is unclear whether this discrepancy is a result of functional impairments. OBJECTIVE:   To compare patient-reported outcomes (PROs), dynamic balance, dynamic functional performance, strength, and muscular endurance in athletes who have returned to sport (RTS) and athletes who have not returned to sport (NRTS) after ACLR...
May 18, 2018: Journal of Athletic Training
https://www.readbyqxmd.com/read/29775307/selective-hydrogenations-and-dechlorinations-in-water-mediated-by-anionic-surfactant-stabilized-pd-nanoparticles
#11
Giorgio La Sorella, Laura Sperni, Patrizia Canton, Lisa Coletti, Fabrizio Fabris, Giorgio Strukul, Alessandro Scarso
We report a facile, inexpensive and green method for the preparation of Pd nanoparticles in aqueous medium stabilized by anionic sulfonated surfactants sodium 1-dodecanesulfonate 1a, sodium dodecylbenzenesulfonate 1b, dioctyl sulfosuccinate sodium salt 1c and poly(ethylene glycol) 4-nonylphenyl-3-sulfopropyl ether potassium salt 1d simply obtained by stirring aqueous solutions of Pd(OAc)2 with the commercial anionic surfactants further treated under hydrogen atmosphere for variable times. The aqueous Pd nanoparticles solutions were tested in the selective hydrogenation reactions of aryl-alcohols, -aldehydes and -ketones leading to complete conversion to the deoxygenated products even in the absence of strong Brønsted acids in the reduction of aromatic aldehydes and ketones, in the controlled semi-hydrogenation of alkynes leading to alkenes and in the efficient hydro-dechlorination of aromatic substrates...
May 18, 2018: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29775170/rationale-design-and-protocol-of-a-randomized-controlled-trial-of-the-safety-and-efficacy-of-dabigatran-etexilate-versus-dose-adjusted-warfarin-in-patients-with-cerebral-venous-thrombosis
#12
José M Ferro, Francesco Dentali, Jonathan M Coutinho, Adam Kobayashi, Jorge Caria, Marc Desch, Mandy Fraessdorf, Holger Huisman, Hans-Christoph Diener
Rationale To prevent recurrent venous thrombotic events after acute cerebral venous or dural sinus thrombosis, guidelines recommend long-term oral anticoagulation with vitamin K antagonists. Non-vitamin K oral anticoagulant experience in cerebral venous or dural sinus thrombosis is limited to case reports and series. Aim To compare dabigatran with dose-adjusted warfarin in patients with cerebral venous or dural sinus thrombosis for the prevention of recurrent venous thrombotic event. Sample size One hundred and twenty patients...
January 1, 2018: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/29775152/semi-automated-application-for-estimating-subthalamic-nucleus-boundaries-and-optimal-target-selection-for-deep-brain-stimulation-implantation-surgery
#13
John A Thompson, Salam Oukal, Hagai Bergman, Steven Ojemann, Adam O Hebb, Sara Hanrahan, Zvi Israel, Aviva Abosch
OBJECTIVE Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become standard care for the surgical treatment of Parkinson's disease (PD). Reliable interpretation of microelectrode recording (MER) data, used to guide DBS implantation surgery, requires expert electrophysiological evaluation. Recent efforts have endeavored to use electrophysiological signals for automatic detection of relevant brain structures and optimal implant target location. The authors conducted an observational case-control study to evaluate a software package implemented on an electrophysiological recording system to provide online objective estimates for entry into and exit from the STN...
May 18, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29775026/-clinical-study-on-serum-25-oh-d-level-in-patients-with-moderate-to-severe-allergic-rhinitis
#14
J Y Tan, T Liu, L X Zhang
Objective: Through the detection of the serum 25 (OH) D level of patients with moderate to severe allergic rhinitis (AR), we preliminarily explored the mechanism of vitamin D on AR and provided evidence for the control of AR. Method: Eighty cases of moderate to severe AR and 65 healthy adults were selected as the subjects. The level of 25 (OH) D was detected by enzyme-linked immunosorbent assay (ELISA), and the serum 25 (OH) D level of eight common serum allergens in patients with moderate to severe AR was analyzed...
February 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29775025/-study-on-the-mutation-of-filaggrin-gene-in-nasal-polyps
#15
Q Zhou, W L Bai, J X Li
Objective: The aim of this study is to investigate the relationship between Filaggrin ( FLG ) gene mutations and nasal polyps. Method: Genomic DNA was extract from 48 nasal polyps tissues, and 30 samples of inferior turbinate tissues from normal human controls. Two FLG gene mutation points (R501X and 3321delA) were detected by polymerase chain reaction (PCR) first, then detected by polypropylene gel electrophoresis, and finally gene sequencing. Result: The FLG gene c. 3321delA was found in 2 cases (4.17%) of nasal polyps, both of them were heterozygous mutations...
February 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29775024/-sleep-quality-analysis-in-patients-with-unilateral-idiopathic-sudden-sensorineural-hearing-loss
#16
Y J Wang, M M Wang, Z Q Hou, Z M Fang, H B Wang
Objective: To analyze the characteristics of sleep quality and its correlation with the clinical features and hearing curative effects in patients with unilateral idiopathic sudden sensorineural hearing loss (ISSHL). Method: Pittsburgh sleep quality index (PSQI) was applied to evaluate the sleep quality of unilateral ISSHL patients in our department. Patient group is divided into poor sleep quality subgroup (total PSQI score>7 points) and normal sleep subgroup (total PSQI score≤7 points). The differences of Patient group and two subgroups between hearing curative effect in the 30 days after treatment and sleep quality scores were compared and analyzed...
February 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29775015/-the-safety-study-of-percutaneous-dilational-tracheostomy-in-a-large-sample
#17
X Zhai, J L Zhang, J C He, G Liu
Objective: The aim of this study is to analyze the safety of a large number cases of percutaneous dilatation tracheostomy. Method: Retrospective analyzed the clinical data of PDT (1 200 cases) and TT (326 cases) patients which were recruited. The postoperative complications were analyzed statistically. PDT and TT randomized controlled trials (PDT and TT) were conducted with 80 cases in each group. The intraoperative conditions (including operative time, intraoperative bleeding volume and incision size) and postoperative complications in the two groups were statistically analyzed...
February 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29775013/-effects-of-highly-selective-branches-neurotomy-of-vidian-nerve-with-low-temperature-plasma-on-vasoactive-intestinal-peptide-in-nasal-mucosal-cells-of-patients-with-allergic-rhinitis
#18
P He, X J Jin, H Zhao
Objective: The aim of this study is to investigate the effect of highly selective branches neurotomy of vidian nerve with low temperature plasma on the level of vasoactive intestinal peptide in nasal mucosa of patients with allergic rhinitis. Method: Fifty patients with allergic rhinitis were selected as the experimental group. At the same time, 50 normal adults in our hospital were selected as the control group. Highly selective branches neurotomy of vidian nerve with low temperature plasma was performed to observe the changes of vascular intestinal peptide levels in patients with nasal mucosa and the clinical efficacy...
February 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29775005/-determination-and-significance-of-serum-mpo-and-amylin-in-adult-patients-with-osahs-after-short-range-noninvasive-positive-pressure-ventilation
#19
X H Chen, P J Chen, Y Long, Q P Huang
Objective: The aim of this study to investigate the determination and significance of serum MPO and amylin in adult patients with OSAHS after short-range noninvasive positive pressure ventilation. Method: Eighty-seven OSAHS patients were divided into severe group (30 cases), moderate group (30 cases) and mild group (27 cases) according to the AHI range. Twenty-seven outpatient health persons were selected as the control group. Serum amylin and myeloperoxidase were measured by ELISA; Amyloid and myeloperoxidase were reassessed in 30 patients with severe OSAHS after 6 months of combined therapy, and the relationship between amylin, myeloperoxidase and PSG was analyzed...
June 5, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29775001/-expression-and-significance-of-serum-hepatocyte-growth-factor-and-myeloperoxidase-in-patients-with-obstructive-sleep-apnea-hypopnea-syndrome
#20
L B Liao, J M Zhai, G G Chen, Z E Ma, X B Yang, J G Zhang
Objective: The aim of this study is to explore the expression and significance of serum HGF and MPO in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) in adults. Method: Ninety-six cases of OSAHS patients diagnosed by PSG were divided into 3 groups: Heavy, medium and light according to the range of AHI; 32 cases of outpatients were healthy persons as the control group. The serum HGF and MPO were determined by ELISA; HGF and MPO were measured after comprehensive treat with CPAP in patients with severe OSAHS, and the correlation between HGF, MPO and PSG were analyzed...
June 5, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
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