keyword
MENU ▼
Read by QxMD icon Read
search

Posterior fossa tumors

keyword
https://www.readbyqxmd.com/read/28430083/hydrocephalus-treatment-in-children-long-term-outcome-in-975-consecutive-patients
#1
Pierre-Aurelien Beuriat, Stephanie Puget, Giuseppe Cinalli, Thomas Blauwblomme, Kevin Beccaria, Michel Zerah, Christian Sainte-Rose
OBJECTIVE Hydrocephalus remains one of the more common pathologies managed in pediatric neurosurgical units. Endoscopic third ventriculostomy (ETV) has an advantage over ventriculoperitoneal shunting as it enables patients to remain device free. Multiple shunt devices with various valve designs exist, with no one valve proven to be superior to another. The aim of this study was to describe the management of hydrocephalus and its long-term outcome. METHODS The authors retrospectively reviewed the medical records of all patients who had been treated for hydrocephalus at the Hôpital Necker-Enfants Malades in the period from 1985 to 1995...
April 21, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28405869/long-term-neuropsychological-follow-up-of-young-children-with-medulloblastoma-treated-with-sequential-high-dose-chemotherapy-and-irradiation-sparing-approach
#2
Taryn B Fay-McClymont, Danielle M Ploetz, Don Mabbott, Karin Walsh, Amy Smith, Susan N Chi, Elizabeth Wells, Jennifer Madden, Ashley Margol, Jonathan Finlay, Mark W Kieran, Douglas Strother, Girish Dhall, Roger J Packer, Nicholas K Foreman, E Bouffet, Lucie Lafay-Cousin
High-dose chemotherapy (HDC) strategies were developed in brain tumor protocols for young children to prevent neuropsychological (NP) impairments associated with radiotherapy. However, comprehensive NP evaluations of these children treated with such strategies remain limited. We examined the long-term neurocognitive outcomes of young children (<6 years) with medulloblastoma, treated similarly, with a HDC strategy "according to" the chemotherapy regimen of the protocol CCG 99703. This retrospective study included young children less than 6 years of age at diagnosis of medulloblastoma treated from 1998 to 2011 at 7 North American institutions...
April 12, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28399105/-treatment-of-syringomyelia-associated-with-chiari-1-malformation
#3
A A Zuev, G V Kostenko
Syringomyelia (SM) develops due to the disturbance of cerebrospinal fluid dynamics, spinal fixation or a spinal tumor. The disturbance of cerebrospinal fluid dynamics in the area of the foramen magnum leads to the progression of SM in Chiari 1 malformation (CM1). CM1 is the most prevalent pathology of craniovertebral junction associated with SM. The prevalence of CM1 varies from 3 to 8 per 100 000 population but SM is diagnosed in 65% of patients with CM1. Clinical symptoms of CM1 and SM include pain in the occipital area, gait disturbances due to sensitive ataxia, dissociated sensory disorders, dysphagia, paresis of the extremities...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28382975/radiation-induces-progenitor-cell-death-microglia-activation-and-blood-brain-barrier-damage-in-the-juvenile-rat-cerebellum
#4
Kai Zhou, Martina Boström, C Joakim Ek, Tao Li, Cuicui Xie, Yiran Xu, Yanyan Sun, Klas Blomgren, Changlian Zhu
Posterior fossa tumors are the most common childhood intracranial tumors, and radiotherapy is one of the most effective treatments. However, irradiation induces long-term adverse effects that can have significant negative impacts on the patient's quality of life. The purpose of this study was to characterize irradiation-induced cellular and molecular changes in the cerebellum. We found that irradiation-induced cell death occurred mainly in the external germinal layer (EGL) of the juvenile rat cerebellum. The number of proliferating cells in the EGL decreased, and 82...
April 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28371821/telomerase-activation-in-posterior-fossa-group-a-ependymomas-is-associated-with-dismal-prognosis-and-chromosome-1q-gain
#5
Johannes Gojo, Daniela Lötsch, Sabine Spiegl-Kreinecker, Kristian W Pajtler, Katharina Neumayer, Pia Korbel, Asuka Araki, Anita Brandstetter, Thomas Mohr, Volker Hovestadt, Lukas Chavez, Dominik Kirchhofer, Gerda Ricken, Harald Stefanits, Andrey Korshunov, Stefan M Pfister, Karin Dieckmann, Amedeo A Azizi, Thomas Czech, Martin Filipits, Marcel Kool, Andreas Peyrl, Irene Slavc, Walter Berger, Christine Haberler
Background.: Ependymomas account for up to 10% of childhood CNS tumors and have a high rate of tumor recurrence despite gross total resection. Recently, classification into molecular ependymoma subgroups has been established, but the mechanisms underlying the aggressiveness of certain subtypes remain widely enigmatic. The aim of this study was to dissect the clinical and biological role of telomerase reactivation, a frequent mechanism of cancer cells to evade cellular senescence, in pediatric ependymoma...
March 24, 2017: Neuro-oncology
https://www.readbyqxmd.com/read/28342060/glycogen-rich-clear-cell-squamous-cell-carcinoma-originating-in-the-oral-cavity
#6
Zaid H Khoury, Amr Bugshan, Joshua E Lubek, John C Papadimitriou, John R Basile, Rania H Younis
Clear cell squamous cell carcinoma (CCSCC) is a rare histological subtype of squamous cell carcinoma (SCC) that was originally described in the skin. Here, we report a case of a 66-year-old female patient who presented with a fungating ulcerative mass of the left lateral tongue extending anteriorly to the floor of the mouth, and posteriorly to the left retromolar fossa and the oropharynx. The patient had a history of SCC of the left posterior tongue that was treated with partial glossectomy and adjuvant radiotherapy...
March 24, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28301882/infantile-hemangioma-of-the-posterior-fossa-in-a-newborn-early-management-and-long-term-follow-up
#7
Elsa Haine, Annick Sevely, Sergio Boetto, Marie-Bernadette Delisle, Claude Cances
A 21-day-old male infant was admitted with signs of intracranial hypertension. Brain magnetic resonance imaging (MRI) revealed a voluminous mass in the posterior fossa with an intense peripheral enhancement on T1 images with gadolinium. The child was treated secondarily by surgical decompression of the posterior fossa and the lesion was biopsied. The pathological findings indicated infantile hemangioma. Treatment with oral prednisolone was initiated at 3 months, given the lack of tumor involution. Six months after corticotherapy was stopped, repeated MRIs indicated a significant reduction in tumor size and then complete disappearance...
March 16, 2017: Neuropediatrics
https://www.readbyqxmd.com/read/28291428/the-durability-of-endoscopic-third-ventriculostomy-and-ventriculoperitoneal-shunts-in-children-with-hydrocephalus-following-posterior-fossa-tumor-resection-a-systematic-review-and-time-to-failure-analysis
#8
Michael C Dewan, Jaims Lim, Chevis N Shannon, John C Wellons
OBJECTIVE Up to one-third of patients with a posterior fossa brain tumor (PFBT) will experience persistent hydrocephalus mandating permanent CSF diversion. The optimal hydrocephalus treatment modality is unknown; the authors sought to compare the durability between endoscopic third ventriculostomy (ETV) and ventriculoperitoneal shunt (VPS) therapy in the pediatric population. METHODS The authors conducted a systematic review of articles indexed in PubMed between 1986 and 2016 describing ETV and/or VPS treatment success/failure and time-to-failure rate in patients < 19 years of age with hydrocephalus related to a PFBT...
March 10, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28279513/cisterna-magna-meningiomas-without-dural-attachment-report-of-two-cases
#9
Masaaki Kohta, Takashi Sasayama, Tomoaki Nakai, Masaaki Taniguchi, Hiroaki Nagashima, Kazuhiro Tanaka, Katsu Mizukawa, Tomoo Itoh, Eiji Kohmura
Meningiomas within the cisterna magna without dural attachment are extremely rare. To the best of our knowledge, only three cases of meningiomas within the cisterna magna have been reported in the literature. The authors present two cases of patient with the cisterna magna meningioma without dural attachment. (Case 1) A 36-year-old female presented with a 10-month history of numbness in the left hand. Magnetic resonance imaging (MRI) disclosed the presence of a contrast-enhanced tumor in the posterior fossa...
March 2, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/28267399/single-stage-socket-reconstruction-with-vascularised-temporalis-muscle-flap-following-total-orbital-exenteration-description-of-3-surgical-approaches
#10
Kasturi Bhattacharjee, Harsha Bhattacharjee, Ganesh Kuri, Manpreet Singh, Manab Jyoti Barman
We describe the techniques and outcome of three different approaches to transfer the posterior 2/3(rd) temporalis muscle pedicle flap for orbital socket reconstruction following total orbital exenteration. A retrospective interventional series of 9 patients operated between February of 2000 and 2006. We describe three different techniques, namely supraorbital, transorbital and transorbitectomy approach. All patients were followed for minimum of 3 years and muscle trophism with periorbital contour was clinically studied for outcome...
April 2017: Orbit
https://www.readbyqxmd.com/read/28230588/how-to-expose-the-entire-sella-floor-with-minimal-manipulation-during-an-endoscopic-endonasal-transsphenoidal-approach
#11
Do Hyun Kim, Yong-Kil Hong, Sin-Soo Jeun, Yong Jin Park, Soo Whan Kim, Jin Hee Cho, Boo-Young Kim, Sung Won Kim
OBJECTIVE: A method of opening the posterior ethmoid air cells with minimal manipulation is important for adequate exposure of the sella floor and minimal nasal morbidity. METHODS: Between February 2009 and August 2016, 373 patients with skull-base tumors underwent surgery via endoscopic endonasal transsphenoidal approach with the 2-nostrils/4-hands technique using this technique. RESULTS: A linear incision was made laterally toward one-third of the superior turbinate along the superior border of the sphenoid sinus ostium...
February 22, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28212886/primary-ameloblastoma-of-the-temporal-bone
#12
Andro Košec, Jakov Ajduk, Mihael Ries, Robert Trotić
Ameloblastoma is a locally aggressive tumor derived from odontogenic epithelium. Although benign, its clinical behavior can often exhibit malignant characteristics. It is marked by slow and persistent growth with infiltration of adjacent tissues. Almost 70% occur in the mandible in patients older than 30 years. Recurrence of ameloblastoma from inadequate treatment is frequent. Because of its slow growth, recurrences can present decades after primary surgery. A primary ameloblastoma in an area outside the mandibular, maxillary, and infratemporal fossa regions has not been described in detail to date, with only 1 possible case mentioned in the literature...
January 24, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28192784/extra-axial-cerebellopontine-angle-medulloblastoma-in-an-infant
#13
Mukesh Kumar Bhaskar, Manish Jaiswal, Bal Krishna Ojha, Sunil Kumar Singh, Anil Chandra, Mukta Meel, Mohd Faheem
Medulloblastoma is a common tumor of the posterior fossa, representing 20-25% of all pediatric neoplasms. It commonly occurs in the midline (cerebellar vermis) and rarely at the cerebellopontine angle. Most of them are intra-axial, and an extra-axial location of this tumor is very rare. Extra-axial cerebellopontine angle medulloblastoma is extremely uncommon and has never been reported in an infant. We report an extra-axial cerebellopontine angle medulloblastoma in a 1-year-old child.
2017: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28187964/brain-perfusion-and-diffusion-abnormalities-in-children-treated-for-posterior-fossa-brain-tumors
#14
Matthew D Li, Nils D Forkert, Palak Kundu, Cheryl Ambler, Robert M Lober, Terry C Burns, Patrick D Barnes, Iris C Gibbs, Gerald A Grant, Paul G Fisher, Samuel H Cheshier, Cynthia J Campen, Michelle Monje, Kristen W Yeom
OBJECTIVE: To compare cerebral perfusion and diffusion in survivors of childhood posterior fossa brain tumor with neurologically normal controls and correlate differences with cognitive dysfunction. STUDY DESIGN: We analyzed retrospectively arterial spin-labeled cerebral blood flow (CBF) and apparent diffusion coefficient (ADC) in 21 patients with medulloblastoma (MB), 18 patients with pilocytic astrocytoma (PA), and 64 neurologically normal children. We generated ANCOVA models to evaluate treatment effects on the cerebral cortex, thalamus, caudate, putamen, globus pallidus, hippocampus, amygdala, nucleus accumbens, and cerebral white matter at time points an average of 5...
February 7, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28180040/evaluation-of-ventriculoperitoneal-shunt-related-complications-in-intracranial-meningioma-with-hydrocephalus
#15
Shyamal C Bir, Shabal Sapkota, Tanmoy K Maiti, Subhas Konar, Papireddy Bollam, Anil Nanda
Objective Meningioma is a common intracranial tumor that predisposes patients to hydrocephalus which may require a permanent cerebrospinal fluid (CSF) diversion procedure such as ventriculoperitoneal (VP) shunts. We reviewed our long-term experience with VP shunts for the management of hydrocephalus in patients with meningioma. Methods and Materials A total of 48 Patients with meningioma who underwent VP shunt insertion for hydrocephalus from 1990 to 2013 was included in our case series. The study population was evaluated clinically and radiographically after VP shunt placement...
February 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28179177/advantage-of-high-b-value-diffusion-weighted-imaging-for-differentiation-of-hemangioblastoma-from-brain-metastases-in-posterior-fossa
#16
Shumpei Onishi, Takanori Hirose, Takeshi Takayasu, Ryo Nosaka, Manish Kolakshyapati, Taiichi Saito, Yuji Akiyama, Kazuhiko Sugiyama, Kaoru Kurisu, Fumiyuki Yamasaki
OBJECTIVE: It is sometimes difficult to make differential diagnosis between brain metastases and hemangioblastoma in posterior fossa. We assessed whether high b-value diffusion weighted image (DWI) at b-4000 could differentiate these tumors. METHODS: We acquired DWI at 3T magnetic resonance imaging (MRI) with b = 1000 and b = 4000 s/mm(2) in histologically confirmed 12 patients of hemangioblastoma without von-Hippel Lindau disease and 16 patients of brain metastases originating at posterior fossa...
February 4, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28175474/197%C3%A2-considerations-in-relationship-to-the-approach-for-the-treatment-of-lateralized-posterior-fossa-tumors-in-children
#17
Mark Calayag, Brandon C Gabel, David S Hong, Dustin Hatefi, David D Gonda, Hal S Meltzer, Michael L Levy
No abstract text is available yet for this article.
August 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28131206/pik3ca-mutation-in-a-mixed-dysembryoplastic-neuroepithelial-tumor-and-rosette-forming-glioneuronal-tumor-a-case-report-and-literature-review
#18
Philip George Eye, Laurence Davidson, Patrick J Malafronte, Sarah Cantrell, Brett J Theeler
BACKGROUND: Rosette forming glioneuronal tumors are rare, World Health Organization (WHO) grade I novel tumors frequently affecting the fourth ventricle or posterior fossa with typical neuronal pseudorosettes. RGNTs have been described as possessing additional histologic features of DNETs or pilocytic astrocytomas. Activating PIK3CA mutations have been identified as recurring genetic event in RGNTs. METHODS: We report a 35year old man who presented with binocular diplopia, headache, and was found to have a third ventricle tumor...
February 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28109103/-value-of-diffusion-weighted-imaging-1-h-magnetic-resonance-spectroscopy-and-3d-whole-brain-arterial-spin-labeling-in-the-diagnosis-of-medulloblastoma
#19
Dong-Liang Cheng, Wen-Sheng Wang, Yi-Xin Hu, Meng-Lin Chen, Ge Wen, Li-Na Cheng, Jing Wu, Liu-Qing Yan
OBJECTIVE: To explore the value of diffusion-weighted imaging (DWI), (1)H-magnetic resonance spectroscopy (1H-MRS) and 3D whole-brain arterial spin labeling (3D ASL) in the diagnosis of medulloblastoma in the posterior cranial fossa. METHODS: The magnetic resonance imaging (MRI) findings of 16 patients with pathologically confirmed medulloblastoma in the posterior cranial fossa were analyzed retrospectively. All the patients were examined with plane and enhanced brain MRI scans; 5 patients also underwent examinations with DWI, 12 with MRS, and 5 with 3D ASL...
January 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28089417/venous-sinus-compromise-after-pre-sigmoid-transpetrosal-approach-for-skull-base-tumors-a-study-on-the-asymptomatic-incidence-and-report-of-a-rare-dural-arteriovenous-fistula-as-symptomatic-manifestation
#20
Walter C Jean, Daniel R Felbaum, Andrew B Stemer, Michael Hoa, H Jeffrey Kim
The sigmoid sinus is routinely exposed and manipulated during pre-sigmoid, transpetrosal approaches to the skull base, but there is scant data available on the incidence of venous sinus compromise after surgery. We encountered a dural arteriovenous fistula as a result of sigmoid sinus occlusion and examined the incidence of venous sinus thrombosis or narrowing after transpetrosal surgeries. We performed a retrospective analysis of a series of patients treated by the senior surgeons (WCJ, MH, HJK), who underwent either a posterior petrosectomy or translabyrinthine approach for various skull base tumors...
January 12, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
keyword
keyword
71223
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"