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Junhui Law, Ka Wai Kong, Ho-Yin Chan, Winston Sun, Wen Jung Li, Eric Boa Fung Chau, George Kak Man Chan
The development of a novel lead-free microelectromechanical-system (MEMS)-based atomizer using the principle of thermal bubble actuation is presented. It is a low-cost, lead-free design that is environmentally friendly and harmless to humans. It has been tested to be applicable over a wide range of fluid viscosities, ranging from 1 cP (e.g., water) to 200 cP (e.g., oil-like fluid) at room temperature, a range that is difficult to achieve using ordinary atomizers. The results demonstrate that the average power consumption of the atomizer is approximately 1 W with an atomization rate of 0...
January 11, 2017: Scientific Reports
Aleksandr A Sapianik, Ekaterina N Zorina-Tikhonova, Mikhail A Kiskin, Denis G Samsonenko, Konstantin A Kovalenko, Alexey A Sidorov, Igor L Eremenko, Danil N Dybtsev, Alexander J Blake, Stephen P Argent, Martin Schröder, Vladimir P Fedin
The tetranuclear heterometallic complex [Li2Zn2(piv)6(py)2] (1, where piv(-) = pivalate and py = pyridine) has been successfully employed as a presynthesized node for the construction of four porous metal-organic frameworks (MOFs) [Li2Zn2(R-bdc)3(bpy)]·solv (2-R, R-bdc(2-); R = H, Br, NH2, NO2) by reaction with 4,4'-bipyridine (bpy) and terephthalate anionic linkers. The [Li2Zn2] node is retained in the products, representing a rare example of the rational step-by-step design of isoreticular MOFs based on complex heterometallic building units...
January 10, 2017: Inorganic Chemistry
Masoumeh MoayeriKashani, Lai Sai Hin, Shaliza Ibrahim, Nik Meriam Nik Sulaiman
  Detention ponds are one type of stormwater best management practices (BMPs) that can be used for the quantity control of stormwater. The pond works by reducing peak discharge downstream through temporary storage and gradual release. In this paper, a new experimental procedure using particle image velocimetry (PIV) is introduced for a two-dimensional study of the hydrodynamic behavior of fine particles in a specially designed sediment basin. The hydrodynamic behavior of fine particles under different hydraulics parameters was achieved by shifting outlet placement, using different particle-size diameters, varying the distance of the inlet from the water surface, and varying the flow rate...
December 1, 2016: Water Environment Research: a Research Publication of the Water Environment Federation
Adriana Weinberg, Marisa M Mussi-Pinhata, Qilu Yu, Rachel A Cohen, Volia C Almeida, Fabiana Amaral, Jorge Pinto, Maria L B Teixeira, Regina C M Succi, Laura Freimanis, Jennifer S Read, George Siberry
OBJECTIVE: HIV-exposed uninfected infants (HEUs) have frequent severe infection, hospitalization and death. We performed a serologic investigation to determine the role of common childhood respiratory pathogens in the excess incidence of infections in HEUs. DESIGN: Prospective cohort study of mother-infant pairs. METHODS: Among 247 HEUs and 88 HIV-unexposed uninfected (HUU) infant-mother pairs, we measured maternal antibodies to respiratory syncytial virus (RSV) and pneumococcus (PNC 1, 5, 6B, 14); infant antibodies to RSV, influenza A (Flu), parainfluenza viruses (PIV 1, 2, 3), and PNC 1, 5, 6B and 14 were measured at 0 and 6 months, and anti-tetanus antibodies at 6 months...
January 4, 2017: AIDS
Emmett E Whitaker, Fievos L Christofi, Kristen M Quinn, Brianne Z Wiemann, Jason C Xia, Joseph D Tobias, Bruno Bissonnette
PURPOSE: To determine if isoflurane anesthesia without surgery causes systemic inflammation in children. Inflammation is targeted as responsible for the development of many neurologic pathologies. The effect will be evaluated by measuring serum cytokine levels before and after isoflurane anesthesia. The possible neurotoxic effect of anesthetic agents is a concern in pediatric anesthesia. Questions remain as to the true effects of anesthesia alone on systemic inflammation. The current study assesses systemic inflammatory response to general anesthesia in children not exposed to surgical stress...
January 3, 2017: Journal of Anesthesia
Vani Krishnamurthy, Srinivasa Murthy Doreswamy, Sushma Krishnagowda
INTRODUCTION: Peripheral Intravenous Catheters (PIV) are extensively used in sick neonates for administration of medicines and nutrition. When these PIVs are used on intermittent basis, they are flushed with saline in order to keep the hub of the catheter free from blood. Presence of blood in the hub of the catheter can be potentially dangerous as it could facilitate infection. AIM: The aim of this study was to find the magnitude of blood contamination of PIV catheter hub after routine flushing...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
A Desai, Eric Ku, D Fang, C Lawrence, C Iannuzzi, C Shi
PURPOSE: To investigate the effect of contouring the whole breast on reducing the radiation dose to the heart and affected lung in tangential field-in-field 3D breast planning. We hypothesize that contouring the whole breast will simplify the plan normalization process, reduce dose to critical structures, while maintaining treatment plan quality and consistency. METHODS: Twenty previously treated breast cancer patients using tangential field-in-field 3D planning technique were randomly selected...
June 2016: Medical Physics
A Sandu, S Thompson, A Ayan, J Woollard, N Gupta
PURPOSE: To retrospectively evaluate the planning quality of a sample of intracranial, linac-based, dynamic arc MLC and VMAT stereotactic plans by calculating the effective gradient, Conformity Score (CGIc) and Gradient Score Index (CGIg), and determine if the Conformity/Gradient Index (CGI) may be a useful metric to guide our current treatment planning process. METHODS: We evaluated single lesion VMAT, single lesion dynamic arc, and single isocenter, 2-lesion linac-based, intracranial, VMAT treatment plans originally created in Eclipse™...
June 2016: Medical Physics
K Jassal, B Sarkar, T Ganesh, H Kaur, U Giri, B Mohanti, A Munshi
PURPOSE: The study investigates the effect of fluence smoothing parameter on VMAT plans for ten head-neck cancer patients using Monaco5.00.04. METHODS: VMAT plans were created using Monaco5.00.04 planning system for 10 head-neck patients. Four plans were generated for each patient using available smoothing parameters i.e. high, medium, low and off. The number of monitor units required to deliver 1 cGy was defined as a modulation degree; and was taken as a measure of plan complexity...
June 2016: Medical Physics
Y Chen, C Li, C Yang
PURPOSE: Safe treatment of the maximum tolerable brain metastases with GK in single patient-clinical findings METHODS: A patient diagnosed with stage IV NSCLC has received 6 courses of Gamma Knife radiosurgery (GKRS) treatments. The plans were generated with GammaPlan (version 10.1.1), six courses of treatment were administered in 2.5 years. A total of 53 metastases were treated with retreatment foci (n = 5) and planned on newly identified lesions (n = 48). Individual prescription dose varied from 12 Gy to 24 Gy...
June 2016: Medical Physics
K Li
PURPOSE: To evaluate the clinical rationale for Truebeam and Trilogy Linac machines from Varian Medical System as exchangeable treatment modalities in the same radiation oncology department. METHODS: Intensity Modulated Radiotherapy (IMRT) plans for different diseases were selected for this study. These disease sites included brain, head and neck, breast, lung, and prostate. The parameters selected for this study were the energy amount, Monitor Unit (MU); dose coverage of target reflected by prescription isodose volume(PIV); dose spillage described by the volume of 50% isodoseline of the prescription; and dose homogeneities represented by the maximum dose (MaxD) and the minimum dose (MinD) of target volume (TV) and critical structure (CS)...
June 2016: Medical Physics
Mariachiara Siciliano, Federico Migliore, Luigi Badano, Emanuele Bertaglia, Gianni Pedrizzetti, Stefano Cavedon, Alessandro Zorzi, Domenico Corrado, Sabino Iliceto, Denisa Muraru
AIMS: To characterize the effect of multipoint pacing (MPP) compared to biventricular pacing (BiV) on left ventricle (LV) mechanics and intraventricular fluid dynamics by three-dimensional echocardiography (3DE) and echocardiographic particle imaging velocimetry (Echo-PIV). METHODS AND RESULTS: In 11 consecutive patients [8 men; median age 65 years (57-75)] receiving cardiac resynchronization therapy (CRT) with a quadripolar LV lead (Quartet,St.Jude Medical,Inc...
December 26, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Yoshimasa Mori, Naoki Kaneda, Masahiro Hagiwara, Tuneo Ishiguchi
OBJECTIVE: The efficacy of stereotactic radiosurgery (SRS) using Gamma Knife (GK) (Elekta, Tokyo) is well known. Recently, Automatic Brain Metastases Planning (ABMP) Element (BrainLAB, Tokyo) for a LINAC-based radiation system was commercially released. It covers multiple off-isocenter targets simultaneously inside a multi-leaf collimator field and enables SRS / stereotactic radiotherapy (SRT) with a single group of LINAC-based dynamic conformal multi-arcs (DCA) for multiple brain metastases...
November 15, 2016: Curēus
François Goehringer, Fabrice Bonnet, Dominique Salmon, Patrice Cacoub, Aissatou Paye, Genevieve Chêne, Philippe Morlat, Thierry May
OBJECTIVE: To describe causes of death and their trends from 2000 to 2010 among treated HIV-infected patients with immunovirologic success (PIVS) in France. DESIGN: Prospective multi-center observational survey Participants: Deceased HIV-infected people from a French national sample of 90 clinical sites providing HIV care and treatment, representing a cohort of 82,000 patients in 2010. MEASUREMENT: Underlying causes of death and characteristics of deceased patients were prospectively recorded in 2000, 2005 and 2010 using a standardized form...
December 16, 2016: AIDS Research and Human Retroviruses
Brad J Gemmell, Stephanie M Fogerson, John H Costello, Jennifer R Morgan, John O Dabiri, Sean P Colin
Swimming animals commonly bend their bodies to generate thrust. For undulating animals such as eels and lampreys, their bodies bend in the form of waves that travel from head to tail. These kinematics accelerate the flow of adjacent fluids, which alters the pressure field in a manner that generates thrust. We used a comparative approach to evaluate the cause-and-effect relationships in this process by quantifying the hydrodynamic effects of body kinematics at the body-fluid interface of the lamprey, Petromyzon marinus, during steady-state swimming...
December 15, 2016: Journal of Experimental Biology
Nikolai V Rostovskii, Julia O Ruvinskaya, Mikhail S Novikov, Alexander F Khlebnikov, Ilia A Smetanin, Anastasiya V Agafonova
4-Aminopyrrole-3-carboxylates and pyrazine-2-carboxylates were synthesized from 5-alkoxyisoxazoles and 1-sulfonyl-1,2,3-triazoles by tuning the Rh(II) catalyst and the reaction conditions. The reaction in chloroform at 100 °C under Rh2(OAc)4 catalysis provides 4-aminopyrrole-3-carboxylates in good yields. The use of Rh2(Piv)4 in refluxing toluene results in the formation of 1,2-dihydropyrazine-2-carboxylates as the main products, which can be converted by a one-pot procedure to pyrazine-2-carboxylates by heating with catalytic amounts of TsOH...
December 14, 2016: Journal of Organic Chemistry
V M Parfenyev, S S Vergeles, V V Lebedev
Recently a theoretical scheme explaining the vorticity generation by surface waves in liquids was developed [Phys. Rev. Lett. 116, 054501 (2016)PRLTAO0031-900710.1103/PhysRevLett.116.054501]. Here we study how a thin (monomolecular) film presented on the surface of liquid affects the generated vorticity. We demonstrate that the vorticity becomes parametrically larger than for the case of liquid with a free surface, and the parameter is the quality factor of surface waves up to numerical factor. We also discuss the PIV experimental scheme intended to observe the generated vorticity and find that Stokes drift influences the measured velocity field...
November 2016: Physical Review. E
Pitambar Patel, Gongutri Borah
Herein we disclose the first report on the synthesis of oxindole derivatives from acetanilide via Ir(iii)-catalyzed intermolecular C-H functionalization with diazotized Meldrum's acid. A broad range of substituted anilides were found to react smoothly under the Ir(iii)-catalytic system to afford the corresponding N-protected oxindoles. The N-protecting groups, such as Ac, Bz or Piv, can be easily removed to furnish the oxindole. Various synthetic applications of the synthesized oxindole were also demonstrated...
December 22, 2016: Chemical Communications: Chem Comm
A Campos Marin, T Grossi, E Bianchi, G Dubini, D Lacroix
Transport properties of 3D scaffolds under fluid flow are critical for tissue development. Computational fluid dynamics (CFD) models can resolve 3D flows and nutrient concentrations in bioreactors at the scaffold-pore scale with high resolution. However, CFD models can be formulated based on assumptions and simplifications. μ-Particle image velocimetry (PIV) measurements should be performed to improve the reliability and predictive power of such models. Nevertheless, measuring fluid flow velocities within 3D scaffolds is challenging...
December 12, 2016: Annals of Biomedical Engineering
Sourav Biswas, Sourav Das, Tulika Gupta, Saurabh Kumar Singh, Michael Pissas, Gopalan Rajaraman, Vadapalli Chandrasekhar
A family of five isostructural butterfly complexes with a tetranuclear [Ln4 ] core of the general formula [Ln4 (LH)2 (μ2 -η(1) η(1) Piv)(η(2) -Piv)(μ3 -OH)2 ]⋅x H2 O⋅y MeOH⋅z CHCl3 (1: Ln=Dy(III) , x=2, y=2, z=0; 2: Ln=Tb(III) , x=0, y=0, z=6; 3: Ln=Er(III) , x=2, y=2, z=0; 4: Ln=Ho(III) , x=2, y=2, z=0; 5: Ln=Yb(III) , x=2, y=2, z=0; LH4 =6-{[bis(2-hydroxyethyl)amino]methyl}-N'-(2-hydroxy-3-methoxybenzylidene)picolinohydrazide; PivH=pivalic acid) was isolated and characterized both structurally and magnetically...
December 19, 2016: Chemistry: a European Journal
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