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https://www.readbyqxmd.com/read/28702715/-the-eu-portal-implementation-importance-and-features
#1
REVIEW
Harald von Aschen, Hartmut Krafft
The European Medicines Agency (EMA) is developing a web-based EU portal with a database "at Union level as a single entry point for the submission of data and information relating to clinical trials in accordance with" the new EU regulation No. 536/2014. The specifications are mostly published, but some documents are still missing. Because the project is integrated and has dependencies on other projects, this could result in other specification upgrades. The IT solution is under ongoing development until project completion in quarter III of 2019...
July 12, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/28700368/regional-anesthesia-and-analgesia-in-cancer-care-is-it-time-to-break-the-bad-news
#2
Mir W Sekandarzad, André A J van Zundert, Chris W Doornebal, Markus W Hollmann
PURPOSE OF REVIEW: There is ongoing controversy regarding the tumor-protective effects of regional anesthesia in patients undergoing cancer surgery. Evidence of up-to-date systematic reviews will be presented alongside recent updates on the effects of opioids and local anesthetics. RECENT FINDINGS: In recent years, the literature regarding the effects of regional anesthesia techniques on cancer recurrence has raised many unanswered questions. Ongoing randomized controlled trials may not be able to shed light on the controversial discussion regarding the tumor protective effects of regional anesthesia because the expected effect size and event rate in those studies may be overstated...
July 11, 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/28690460/analysis-of-player-statistics-in-major-league-baseball-players-before-and-after-achilles-tendon-repair
#3
Bryan M Saltzman, Matthew W Tetreault, Daniel D Bohl, Danielle Tetreault, Simon Lee, Bernard R Bach
BACKGROUND: No currently available literature evaluates the effect of Achilles tendon repair on professional baseball players in the Major League Baseball (MLB). QUESTIONS/PURPOSES: The purpose of this study was to determine the impact of Achilles tendon rupture and repair on MLB players in terms of return to play and batting/fielding performance metrics. METHODS: Achilles tendon rupture data were retrospectively collected using information from the MLB disabled list, injury reports, MLB game summaries, player profiles, and publicly available news articles...
July 2017: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://www.readbyqxmd.com/read/28682246/breakingnews-article-annotation-by-image-and-text-processing
#4
Arnau Ramisa, Fei Yan, Francesc Moreno-Noguer, Krystian Mikolajczyk
Current approaches lying in the intersection of computer vision and NLP have achieved unprecedented breakthroughs in tasks like automatic captioning or image retrieval. Most of these methods, though, rely on training sets of images associated with annotations that specifically describe the visual content. This paper proposes going a step further and explores more complex cases where textual descriptions are loosely related to images. We focus on the particular domain of News. We introduce new deep learning methods that address source and popularity prediction, article illustration, and article geolocation...
June 30, 2017: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28666771/physicians-psychophysiological-stress-reaction-in-medical-communication-of-bad-news-a-critical-literature-review
#5
REVIEW
Regina Katharina Studer, Brigitta Danuser, Patrick Gomez
INTRODUCTION: Stress is a common phenomenon in medical professions. Breaking bad news (BBN) is reported to be a particularly distressing activity for physicians. Traditionally, the stress experienced by physicians when BBN was assessed exclusively using self-reporting. Only recently, the field of difficult physician-patient communication has used physiological assessments to better understand physicians' stress reactions. METHOD: This paper's goals are to (a) review current knowledge about the physicians' psychophysiological stress reactions in BBN situations, (b) discuss methodological aspects of these studies and (c) suggest directions for future research...
June 27, 2017: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/28663137/online-news-media-reporting-of-football-related-fatalities-in-australia-a-matter-of-life-and-death
#6
Lauren V Fortington, Sheree Bekker, Caroline F Finch
OBJECTIVES: While deaths in sports settings are rare, they do occur. To develop an understanding of the sports and people most at risk, and to identify opportunities for prevention, routine and systematic data detailing the occurrence of these fatalities is required. There is currently no routine reporting of data of this nature in Australia. As there is often strong community interest in these incidents, the media offers an opportunity for surveillance. However before this can occur, understanding of the terminology used by the media is required...
June 21, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28635189/a-new-deal-for-the-monaldi-archives-for-chest-disease
#7
The Editors
The Editors: Antonio Spanevello, Bruno Balbi, Francesco Fattirolli, Furio Colivicchi.This issue marks a change in the Editorial Board of Monaldi Archives for Chest Disease. We would like to take this opportunity to impart some news on the current status of the journal. Our submissions are increasing, citations to our papers are rising, and recognition of the journal is broadening. Overall, 2016 has been a good year for the journal. Several changes are being made and several more are coming soon. Yet, focussing on the results achieved only is not our main goal, hence we now direct our efforts toward reaching an even greater impact...
May 18, 2017: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/28622038/see-something-say-something-correction-of-global-health-misinformation-on-social-media
#8
Leticia Bode, Emily K Vraga
Social media are often criticized for being a conduit for misinformation on global health issues, but may also serve as a corrective to false information. To investigate this possibility, an experiment was conducted exposing users to a simulated Facebook News Feed featuring misinformation and different correction mechanisms (one in which news stories featuring correct information were produced by an algorithm and another where the corrective news stories were posted by other Facebook users) about the Zika virus, a current global health threat...
June 16, 2017: Health Communication
https://www.readbyqxmd.com/read/28621753/media-coverage-of-alcohol-issues-a-critical-political-economy-framework-a-case-study-from-ireland
#9
Julien Mercille
There is a growing literature on news media representations of alcohol-related issues. However, current scholarship has neglected critical political economic frameworks to interpret media coverage of alcohol. This paper presents such a framework that conceives of news organisations as corporations that share the values and interests of political and economic elites. The media are thus expected to present viewpoints that are more aligned with the alcohol industry than the scientific consensus on public health policy would warrant...
June 16, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28592542/gender-parity-trends-for-invited-speakers-at-four-prominent-virology-conference-series
#10
Robert F Kalejta, Ann C Palmenberg
Scientific conferences are most beneficial to participants when they showcase significant new experimental developments, accurately summarize the current state of the field, and provide strong opportunities for collaborative networking. A top-notch slate of invited speakers, assembled by conference organizers or committees, is key to achieving these goals. The perceived underrepresentation of female speakers at prominent scientific meetings is currently a popular topic for discussion, but one that often lacks supportive data...
June 7, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28588013/building-a-visual-aid-for-a-triage-tool-in-a-developing-health-service
#11
Mir Saaduddin Ahmad, Darryl R Wood
Resources in the modern day emergency department are often stretched, and this holds true more so in developing services. With limited manpower, it is essential that efficient tools are created so that processes can be run safely. Here we pilot the use of a vital signs matrix in a medical camp in Dhaka to screen patients at triage. We further modified this matrix to include the National Early Warning Score as our recording of the NEWS have remained poor in triage. A trial and validation study for the use of this matrix in an NHS setting is currently underway...
June 6, 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/28562100/developments-with-experimental-and-investigational-drugs-for-axial-spondyloarthritis
#12
REVIEW
Gaëlle Clavel, Marie-Christophe Boissier, Johanna Sigaux, Luca Semerano
Axial spondyloarthritis (AxS pA) is a chronic inflammatory disease for which, until recently, there were no valid therapeutic alternatives to TNF-α blocking agents. This unmet clinical need led to explore several therapeutic targets, from proinflammatory cytokines to intracellular signaling systems. The recent approval of Secukinumab, an anti-IL-17A monoclonal antibody, marked a new step in the evolution of AxSpA treatment. Areas covered: the authors review and discuss all the biological or synthetic agents that are currently developed or that have been tested in AxSpA...
July 2017: Expert Opinion on Investigational Drugs
https://www.readbyqxmd.com/read/28557549/clinician-targeted-mobile-apps-in-palliative-care-a-systematic-review
#13
Salimah H Meghani, Meredith A MacKenzie, Brianna Morgan, Youjeong Kang, Anum Wasim, Saleem Sayani
BACKGROUND: The availability of smartphone applications has increased rapidly including applications related to palliative care. The scope of these available apps has not been synthesized. OBJECTIVE: The purpose of this study was to identify and review available palliative care-related smartphone applications for clinicians. DESIGN: Smartphone application platform stores, for example, App Store iOS, Google Play Store, Windows App-Microsoft Store, and Blackberry World App store were searched (December 2016) using relevant key words...
May 30, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28522165/a-new-legal-treatment-for-psychopaths-perplexities-for-legal-thinkers
#14
REVIEW
Maria Isabel Gonzalez-Tapia, Ingrid Obsuth, Rachel Heeds
Public perception, fueled not only by popular and news media but also by expert claims that psychopaths are archetypes of evil: incorrigible, remorseless, cold-blooded criminals, whose crimes manifest in the most extreme levels of violence. But is there empirical evidence that psychopaths truly are what they are portrayed to be? If so, should the law respond, and adjust its treatment of psychopaths in court - permitting psychopathy to be admitted under an insanity defense and/or resulting in mitigation? In this paper, we demonstrate that fundamental questions from the law to science remain unanswered and must be addressed before any alternative treatment of psychopathy can be considered...
May 15, 2017: International Journal of Law and Psychiatry
https://www.readbyqxmd.com/read/28465272/global-diversity-and-academic-success-of-foreign-trained-academic-neurosurgeons-in-the-united-states
#15
Akshitkumar M Mistry, Nishant Ganesh Kumar, Rebecca A Reynolds, Andrew T Hale, John C Wellons, Robert P Naftel
OBJECTIVE: To quantify the proportion of academic neurosurgeons practicing in the United States who acquired residency training outside of the United States and compare their training backgrounds and academic success with those who received their residency training in the United States. METHODS: We identified 1338 clinically active academic neurosurgeons from 104 programs that participated in the neurosurgery residency match in the United States in January-February 2015...
April 30, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28451562/designing-a-medical-tourism-website-a-qualitative-study
#16
Mahnaz Samadbeik, Heshmatollah Asadi, Mohammad Mohseni, Afsaneh Takbiri, Ahmad Moosavi, Ali Garavand
BACKGROUND: Informing plays a prominent role in attracting medical tourists. The enjoyment of proper medical information systems is one of the most important tools for the attraction of medical tourists. Iran's ability in designing and implementing information networks has remained largely unknown. The current study aimed to explore information needs for designing a medical tourism website. METHODS: This qualitative study was conducted in 2015 for designing Hospital Medical-Tourism Website (HMTW)...
February 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28450127/carcinogenicity-of-consumption-of-red-meat-and-processed-meat-a-review-of-scientific-news-since-the-iarc-decision
#17
REVIEW
José L Domingo, Martí Nadal
In October 2015, the International Agency for Research on Cancer (IARC) issued a press release on the results of the evaluation of the carcinogenicity of red and processed meat. Based on the accumulated scientific literature, the consumption of red meat was classified as "probably carcinogenic to humans" and processed meat as "carcinogenic to humans". Given the importance of this topic, this review was aimed at revising the current state-of-the-art on the carcinogenicity of red and processed meat, some time after the IARC decision...
April 24, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28443376/remote-ischemic-conditioning-and-renal-protection
#18
Georgios Giannopoulos, Dimitrios A Vrachatis, Vasiliki Panagopoulou, Manolis Vavuranakis, Michael W Cleman, Spyridon Deftereos
Over the course of the last 2 decades, the concept of remote ischemic conditioning (RIC) has attracted considerable research interest, because RIC, in most of its embodiments offers an inexpensive way of protecting tissues against ischemic damage inflicted by a number of medical conditions or procedures. Acute kidney injury (AKI) is a common side effect in the context of various medical procedures, and RIC has been suggested as a means of reducing its incidence. Outcomes regarding kidney function have been reported in numerous studies that evaluated the effects of RIC in a variety of settings (eg, cardiac surgery, interventions requiring intravenous administration of contrast media)...
July 2017: Journal of Cardiovascular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28431767/the-new-drug-conditional-approval-process-in-china-challenges-and-opportunities
#19
REVIEW
Xuefang Yao, Jinxi Ding, Yingfang Liu, Penghui Li
PURPOSE: Our aim was to characterize the newly established new drug conditional approval process in China and discuss the challenges and opportunities with respect to new drug research and development and registration. METHODS: We examined the new approval program through literature review, law analysis, and data analysis. Data were derived from published materials, such as journal articles, government publications, press releases, and news articles, along with statistical data from INSIGHT-China Pharma Databases, the China Food and Drug Administration website, the Center for Drug Evaluation website, the US Food and Drug Administration website, and search results published by Google...
April 18, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28407525/mind-the-gap-exploring-information-gaps-for-the-development-of-an-online-resource-hub-for-epilepsy-and-depression
#20
Rachel E Crooks, Meaghan Bell, Scott B Patten, Samuel Wiebe, Jayna Holroyd-Leduc, Andrew G Bulloch, Sophia Macrodimitris, Aaron Mackie, Khara M Sauro, Paolo Federico, Nathalie Jetté
PURPOSE: Depression is common in epilepsy, and is often under-detected and under-treated. The motivation to create a depression eHub for persons with epilepsy is to connect them to the best available online resources to effectively manage their depression. The study sought to: 1) identify facilitators and barriers to accessing resources related to management of epilepsy and/or depression and 2) discuss gaps in available resources (free and in the public domain) and 3) identify suggestions for future content...
May 2017: Epilepsy & Behavior: E&B
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