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https://www.readbyqxmd.com/read/29808443/improving-evidence-dissemination-and-accessibility-through-a-mobile-based-resource-platform
#1
Zheng Zhu, Weijie Xing, Yan Hu, Yingfeng Zhou, Ying Gu
Current mobile information technologies fundamentally influence evidence dissemination from the perspective of both evidence seekers and evidence providers. However, there is no related study which tried using a mobile-based platform to disseminate evidence in China. The main object of this study is to develop a mobile-based evidence resource platform and to evaluate its effects of improving nurses' access to evidence-based practice resources and meeting users' demands. The mobile-based evidence resource platform was developed in 2014...
May 28, 2018: Journal of Medical Systems
https://www.readbyqxmd.com/read/29799343/the-history-of-therapeutic-hypothermia-and-its-use-in-neurosurgery
#2
Michael A Bohl, Nikolay L Martirosyan, Zachary W Killeen, Evgenii Belykh, Joseph M Zabramski, Robert F Spetzler, Mark C Preul
Despite an overwhelming history demonstrating the potential of hypothermia to rescue and preserve the brain and spinal cord after injury or disease, clinical trials from the last 50 years have failed to show a convincing benefit. This comprehensive review provides the historical context needed to consider the current status of clinical hypothermia research and a view toward the future direction for this field. For millennia, accounts of hypothermic patients surviving typically fatal circumstances have piqued the interest of physicians and prompted many of the early investigations into hypothermic physiology...
May 25, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29795578/public-reaction-to-chikungunya-outbreaks-in-italy-insights-from-an-extensive-novel-data-streams-based-structural-equation-modeling-analysis
#3
Naim Mahroum, Mohammad Adawi, Kassem Sharif, Roy Waknin, Hussein Mahagna, Bishara Bisharat, Mahmud Mahamid, Arsalan Abu-Much, Howard Amital, Nicola Luigi Bragazzi, Abdulla Watad
The recent outbreak of Chikungunya virus in Italy represents a serious public health concern, which is attracting media coverage and generating public interest in terms of Internet searches and social media interactions. Here, we sought to assess the Chikungunya-related digital behavior and the interplay between epidemiological figures and novel data streams traffic. Reaction to the recent outbreak was analyzed in terms of Google Trends, Google News and Twitter traffic, Wikipedia visits and edits, and PubMed articles, exploiting structural modelling equations...
2018: PloS One
https://www.readbyqxmd.com/read/29790197/establishing-a-publicly-available-national-database-of-us-news-articles-reporting-agriculture-related-injuries-and-fatalities
#4
Bryan Weichelt, Marsha Salzwedel, Scott Heiberger, Barbara C Lee
BACKGROUND: The AgInjuryNews system and dataset are a news report repository and information source for agricultural safety professionals, policymakers, journalists, and law enforcement officials. METHODS: AgInjuryNews was designed as a primary storage and retrieval system that allows users to: identify agricultural injury/fatality events; identify injury agents and emerging issues; provide safety messages for media in anticipation of trends; and raise awareness and knowledge of agricultural injuries and prevention strategies...
May 22, 2018: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/29782309/in-memoriam-assistant-professor-kre%C3%A5-imir-kostovi%C3%A4-md-phd-16-october-1969-15-october-2017
#5
Branka Marinović
On a Sunday afternoon almost six months ago, we were deeply moved by the news that our Krešimir is no longer with us. The sad news spread from Sarajevo with the speed only most horrible and saddest news can achieve. And everybody who was reached by these news wondered whether it was possible and whether it was true. Because our professor Kostović left us a day before his 48th birthday. Krešimir Kostović was born on the 16th October 1969 in Zagreb, where he completed primary and secondary education. He enrolled at the University of Zagreb School of Medicine in 1988, and got his medical degree in 1995...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29751526/molecular-responses-to-the-zika-virus-in-mosquitoes
#6
REVIEW
Catalina Alfonso-Parra, Frank W Avila
The Zika virus (ZIKV), originally discovered in 1947, did not become a major concern until the virus swept across the Pacific and into the Americas in the last decade, bringing with it news of neurological complications and birth defects in ZIKV affected areas. This prompted researchers to dissect the molecular interactions between ZIKV and the mosquito vector in an attempt to better understand not only the changes that occur upon infection, but to also identify molecules that may potentially enhance or suppress a mosquito’s ability to become infected and/or transmit the virus...
May 3, 2018: Pathogens
https://www.readbyqxmd.com/read/29703477/treatment-of-venous-thromboembolism-in-patients-with-cancer-what-news-from-clinical-trials
#7
Melina Verso, Laura Franco, Michela Giustozzi, Cecilia Becattini, Giancarlo Agnelli
About 15% of patients with cancer experience one or more episodes of venous thromboembolism (VTE) during the course of their disease. In patients with cancer, VTE has a substantial impact on the quality of life and care. Current guidelines recommend low-molecular-weight heparin (LMWH) as first choice therapy for long-term anticoagulation in cancer patients with VTE. However, there are several practical issues concerning the long-term use of these anticoagulants. In the last years, several direct oral anticoagulants (DOACs) have emerged as alternatives to heparins and vitamin K antagonists for the treatment of VTE, but data regarding both efficacy and safety of DOACs in the subgroup of patients with cancer treatments were limited...
April 2018: Thrombosis Research
https://www.readbyqxmd.com/read/29698086/the-environmental-protection-agency-in-the-early-trump-administration-prelude-to-regulatory-capture
#8
Lindsey Dillon, Christopher Sellers, Vivian Underhill, Nicholas Shapiro, Jennifer Liss Ohayon, Marianne Sullivan, Phil Brown, Jill Harrison, Sara Wylie
We explore and contextualize changes at the Environmental Protection Agency (EPA) over the first 6 months of the Trump administration, arguing that its pro-business direction is enabling a form of regulatory capture. We draw on news articles, public documents, and a rapid response, multisited interview study of current and retired EPA employees to (1) document changes associated with the new administration, (2) contextualize and compare the current pro-business makeover with previous ones, and (3) publicly convey findings in a timely manner...
April 2018: American Journal of Public Health
https://www.readbyqxmd.com/read/29683782/impact-of-an-early-exposure-geriatrics-curriculum-in-an-accelerated-baccalaureate-md-program
#9
Yuya Hagiwara, Juan Pagan-Ferrer, Sandra Sanchez-Reilly
Current standard geriatric curricula and exposure of students to the elderly may be insufficient to influence students' interest in geriatric medicine. We developed an innovative curriculum to address this gap. This study aimed to identify knowledge, skill, and attitude changes of first-year students in an accelerated baccalaureate-MD program toward geriatrics after participation in an early-exposure geriatrics curriculum (GC). The GC consisted of fifteen 3-hr interactive teaching sessions facilitated by various health professionals...
April 23, 2018: Gerontology & Geriatrics Education
https://www.readbyqxmd.com/read/29667872/detecting-european-rabbit-oryctolagus-cuniculus-disease-outbreaks-by-monitoring-digital-media
#10
David E Peacock, Tiggy L Grillo
  Digital media and digital search tools offer simple and effective means to monitor for pathogens and disease outbreaks in target organisms. Using tools such as Rich Site Summary feeds, and Google News and Google Scholar specific key word searches, international digital media were actively monitored from 2012 to 2016 for pathogens and disease outbreaks in the taxonomic order Lagomorpha, with a specific focus on the European rabbit ( Oryctolagus cuniculus). The primary objective was identifying pathogens for assessment as potential new biocontrol agents for Australia's pest populations of the European rabbit...
April 18, 2018: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/29661172/mth1-deficiency-selectively-increases-non-cytotoxic-oxidative-dna-damage-in-lung-cancer-cells-more-bad-news-than-good
#11
Hussein H K Abbas, Kheloud M H Alhamoudi, Mark D Evans, George D D Jones, Steven S Foster
BACKGROUND: Targeted therapies are based on exploiting cancer-cell-specific genetic features or phenotypic traits to selectively kill cancer cells while leaving normal cells unaffected. Oxidative stress is a cancer hallmark phenotype. Given that free nucleotide pools are particularly vulnerable to oxidation, the nucleotide pool sanitising enzyme, MTH1, is potentially conditionally essential in cancer cells. However, findings from previous MTH1 studies have been contradictory, meaning the relevance of MTH1 in cancer is still to be determined...
April 16, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29628513/hot-news-impact-of-low-level-viremia-on-treatment-outcomes-during-art-is-it-time-to-revise-the-definition-of-virological-failure
#12
Eva Poveda, Manuel Crespo
The level of HIV-RNA in plasma (HIV viral load) is the main marker used to monitor the virological response to antiretroviral therapy (ART) in HIV-infected patients. The threshold used to define virological suppression has historically been dictated by the limits of detection of the commercial assays used to quantify the plasma viral load. Thus, as more sensitive assays have proliferated and become more widely available, the definition has shifted from < 400 cop/mL with the first generation assays, to < 50 cop/mL, to < 20 cop/mL currently...
January 2018: AIDS Reviews
https://www.readbyqxmd.com/read/29607245/future-of-health-findings-from-a-survey-of-stakeholders-on-the-future-of-health-and-healthcare-in-england
#13
Jennie Corbett, Camilla d'Angelo, Lorenzo Gangitano, Jon Freeman
This article presents findings from a survey conducted by RAND Europe at the request of the National Institute for Health Research (NIHR) to gather and synthesise stakeholder views on the future of health and healthcare in England in 20 to 30 years' time. The aim of the research was to generate an evidenced-based picture of the future health and healthcare needs, and how it might differ from today, in order to inform strategic discussions about the future priorities of the NIHR and the health and social care research communities more broadly...
April 2018: Rand Health Quarterly
https://www.readbyqxmd.com/read/29598752/a-neglected-population-media-consumption-perceived-risk-and-fear-of-crime-among-international-students
#14
Luzi Shi
The 4.5 million international students worldwide bring in multifold benefits to the advancement of culture, economy, and national security in education host countries. Surprisingly, few prior studies have explored international students' fear of crime, which may harm their mental and physical health and undermine their educational achievements. The current study aims to fill in this research void by investigating international students' fear of crime in line with the cultivation theoretical framework, which postulates that media consumption cultivates fear of crime...
March 1, 2018: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29574605/climate-change-and-the-impact-on-respiratory-and-allergic-disease-2018
#15
REVIEW
Jeffrey G Demain
PURPOSE OF REVIEW: The purpose of this paper is to review allergic respiratory disease related to indoor and outdoor exposures and to examine the impact of known and projected changes in climate. The global burden of disease directly attributed to climate change is very difficult to measure and becomes more challenging when the capacity of humans to adapt to these changes is taken into consideration. Allergic respiratory disease, such as asthma, is quite heterogenous, though closely associated with environmental and consequently immunologic interaction...
March 24, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29571952/an-evaluation-of-trends-in-patient-and-public-awareness-of-ir
#16
David Heister, Susan Jackson, Margaret Doherty-Simor, Isabel Newton
PURPOSE: To evaluate patient and public awareness of interventional radiology (IR). MATERIALS AND METHODS: This single-center study prospectively administered voluntary paper surveys to 80 patients in an academic hospital radiology waiting room. Separate, Internet-based surveys were administered to the general public. Additionally, Internet metadata were used to evaluate relative search engine activity and IR-related news coverage compared with similar procedural specialties...
May 2018: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29564256/a-comparative-study-of-epidemiological-investigations-of-malaria-outbreaks-and-related-deaths-in-two-districts-of-jharkhand-during-the-same-prewinter-season-using-shoe-leather-epidemiology
#17
Dewesh Kumar, Shashi Bhushan Singh, Abhishek Kumar, Anupam Kishore, Vivek Kashyap
Background: Following news of deaths in two districts of Jharkhand (West Singhbum and Garhwa) in November 2016, epidemiological investigations were contemplated to investigate any current outbreak of falciparum malaria and deaths attributed to it. Methodology: The epidemiological investigations, verbal autopsy of suspected deaths attributed to malaria and keys interviews were conducted in the 2nd and 4th week of November 2016 in Khuntpani and Dhurki block of West Singhbum and Garhwa districts, respectively, following a strict protocol...
October 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29558944/intelligent-judgements-over-health-risks-in-a-spatial-agent-based-model
#18
Shaheen A Abdulkareem, Ellen-Wien Augustijn, Yaseen T Mustafa, Tatiana Filatova
BACKGROUND: Millions of people worldwide are exposed to deadly infectious diseases on a regular basis. Breaking news of the Zika outbreak for instance, made it to the main media titles internationally. Perceiving disease risks motivate people to adapt their behavior toward a safer and more protective lifestyle. Computational science is instrumental in exploring patterns of disease spread emerging from many individual decisions and interactions among agents and their environment by means of agent-based models...
March 20, 2018: International Journal of Health Geographics
https://www.readbyqxmd.com/read/29553937/tackling-an-epidemic-new-and-emerging-opioid-addiction-treatments-offer-hope-for-solutions-to-this-crisis
#19
Mary Bates
The opioid epidemic is dominating news headlines and inspiring greater calls for political action in the United States. While opioid addiction isn't a new issue, its devastating consequences are now being felt across the country. "What's got everybody's attention is that so many people are dying," says Dr. Richard Ries (Figure 1), director of the University of Washington School of Medicine?s addictions divisions and medical director of the Outpatient Addictions Program at Harborview Medical Center, Seattle...
March 2018: IEEE Pulse
https://www.readbyqxmd.com/read/29541161/3c-and-3c-based-techniques-the-powerful-tools-for-spatial-genome-organization-deciphering
#20
REVIEW
Jinlei Han, Zhiliang Zhang, Kai Wang
It is well known that the chromosomes are organized in the nucleus and this spatial arrangement of genome play a crucial role in gene regulation and genome stability. Different techniques have been developed and applied to uncover the intrinsic mechanism of genome architecture, especially the chromosome conformation capture (3C) and 3C-derived methods. 3C and 3C-derived techniques provide us approaches to perform high-throughput chromatin architecture assays at the genome scale. However, the advantage and disadvantage of current methodologies of C-technologies have not been discussed extensively...
2018: Molecular Cytogenetics
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