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Limb proportion

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https://www.readbyqxmd.com/read/28320133/rest-tremor-in-parkinson-s-disease-body-distribution-and-time-of-appearance
#1
Angelo Fabio Gigante, Roberta Pellicciari, Giovanni Iliceto, Daniele Liuzzi, Paola Vincenza Mancino, Giacomo Emanuele Custodero, Marco Guido, Paolo Livrea, Giovanni Defazio
OBJECTIVE: To assess body distribution and timing of appearance of rest tremor in Parkinson's disease. METHODS: Information was obtained by a computerized database containing historical information collected at the first visit and data collected during the subsequent follow-up visits. Information on rest tremor developed during the follow-up could be therefore obtained by our own observation in a proportion of patients. RESULTS: Among 289 patients, rest tremor was reported at disease onset in 65...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28319251/limb-bone-allometry-in-modern-euro-americans
#2
R L Jantz, L Meadows Jantz
OBJECTIVES: The pattern of static and secular allometry was examined in a time series of limb bone lengths from individuals with birth years ranging from 1840 to 1989. The main hypothesis investigated was that secular changes in limb proportions, as seen in changes in the brachial and crural indices, can be explained by allometric responses to increasing size. MATERIALS AND METHODS: Maximum lengths of humerus, radius, femur, and tibia were obtained from 19th and 20th centuries identified skeletons...
March 20, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28315005/effect-of-nitric-oxide-on-renal-autoregulation-during-hypothermia-in-the-rat
#3
Lars Mikael Broman, Mattias Carlström, Örjan Källskog, Mats Wolgast
Hypothermia-induced reduction of metabolic rate is accompanied by depression of both glomerular perfusion and filtration. The present study investigated whether these changes are linked to changes in renal autoregulation and nitric oxide (NO) signalling. During hypothermia, renal blood flow (RBF) and glomerular filtration rate (GFR) were reduced and urine production was increased, and this was linked with reduced plasma cGMP levels and increased renal vascular resistance. Although stimulation of NO production decreased vascular resistance, blood pressure and urine flow, intravenous infusion of the NO precursor L-arginine or the NO donor sodium nitroprusside did not alter RBF or GFR...
March 17, 2017: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/28302696/achievement-of-saturation-targets-in-preterm-infants-32%C3%A2-weeks-gestational-age-in-the-delivery-room
#4
Lani Nui White, Marta Thio, Louise S Owen, C Omar Kamlin, Samantha Sloss, Stuart B Hooper, Peter G Davis, Jennifer A Dawson
BACKGROUND: To reduce the risks of hypoxia and hyperoxia in preterm infants in the delivery room; national and international guidelines recommend titrating supplemental oxygen delivery to achieve specific oxygen saturation (SpO2) targets. Our aim was to measure the proportion of time infants <32 weeks' gestation spent within and outside prescribed SpO2 targets during the first 10 min after birth. METHOD: Prospective observational study using data from a preductal SpO2 sensor and oxygen analyser measuring fraction of inspired oxygen (FiO2) in the inspiratory limb of the respiratory circuit...
March 16, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28294284/the-aetiology-of-chronic-vulval-pain-and-entry-dyspareunia-a-retrospective-review-of-525-cases
#5
Victoria Harris, Gayle Fischer, Jennifer A Bradford
BACKGROUND: There are few published data about the incidence of diagnoses or treatment outcomes, for chronic vulval pain. AIMS: To document diagnoses and treatment outcomes in a cohort of chronic vulval pain presentations. MATERIALS AND METHODS: A retrospective case review of the patient database of a private vulval clinic between January 2011 and March 2015. RESULTS: Five hundred and twenty-five out of 3360 patients (15...
March 13, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28288686/outcomes-of-dysvascular-partial-foot-amputation-and-how-these-compare-to-transtibial-amputation-a-systematic-review-for-the-development-of-shared-decision-making-resources
#6
Michael P Dillon, Matthew Quigley, Stefania Fatone
BACKGROUND: Dysvascular partial foot amputation (PFA) is a common sequel to advanced peripheral vascular disease. Helping inform difficult discussions between patients and practitioners about the level of PFA, or the decision to have a transtibial amputation (TTA) as an alternative, requires an understanding of the current research evidence on a wide range of topics including wound healing, reamputation, quality of life, mobility, functional ability, participation, pain and psychosocial outcomes, and mortality...
March 14, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28284666/anthropometric-and-biomechanical-characteristics-of-body-segments-in-persons-with-spinal-cord-injury
#7
Y Fang, L R Morse, N Nguyen, N G Tsantes, K L Troy
People with spinal cord injury (SCI) experience bone and muscle loss in their paralyzed limbs that is most rapid and severe in the first 3years after injury. Restoration of mechanical loading through therapeutic physical activity may potentially slow or reverse post-SCI bone loss, however, therapeutic targets cannot be developed without accurate biomechanical models. Obesity is prevalent among SCI population, and it alters body composition and further affects parameters of these models. Here, clinical whole body dual-energy X-ray absorptiometry data from people with acute (n=39) and chronic (n=61) SCI were analyzed to obtain anthropometric parameters including segment masses, center of mass location, and radius of gyration for both obese and non-obese individuals...
February 3, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28283596/safety-and-efficacy-of-incobotulinumtoxina-doses-up-to-800-u-in-limb-spasticity-the-tower-study
#8
Jörg Wissel, Djamel Bensmail, Joaquim J Ferreira, Franco Molteni, Lalith Satkunam, Susana Moraleda, Tiina Rekand, John McGuire, Astrid Scheschonka, Birgit Flatau-Baqué, Olivier Simon, Edward T J Rochford, Dirk Dressler, David M Simpson
OBJECTIVE: To evaluate safety (primary objective) and efficacy of increasing doses (400 U up to 800 U) of incobotulinumtoxinA (Xeomin, Merz Pharmaceuticals GmbH) for patients with limb spasticity. METHODS: In this prospective, single-arm, dose-titration study (NCT01603459), patients (18-80 years) with spasticity due to cerebral causes, who were clinically deemed to require total doses of 800 U incobotulinumtoxinA, received 3 consecutive injection cycles (ICs) with 400 U, 600 U, and 600-800 U incobotulinumtoxinA, respectively, each followed by 12-16 weeks' observation...
March 10, 2017: Neurology
https://www.readbyqxmd.com/read/28274772/a-double-blind-randomised-controlled-trial-of-ibuprofen-compared-with-placebo-for-uncomplicated-cellulitis-of-the-upper-or-lower-limb
#9
Joshua S Davis, Carol Mackrow, Paula Binks, Wendy Fletcher, Pascale Dettwiller, Catherine Marshall, Jane Day, William Pratt, Steven Yc Tong
OBJECTIVES: Cellulitis is a common skin infection resulting in inflammation that may take weeks to resolve despite appropriate antibiotics. It is unclear whether the adjunctive use of non-steroidal anti-inflammatory drugs hastens the resolution of inflammation in patients with cellulitis. METHODS: We conducted a double-blind, randomised controlled trial comparing ibuprofen 400mg three times daily for five days with identical placebo in adults with uncomplicated cellulitis of the upper or lower limb who were treated with intravenous cefazolin via an outpatient parenteral antibiotic treatment service at one of two Australian hospitals...
March 5, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28268345/properties-of-the-motor-unit-action-potential-shape-in-proximal-and-distal-muscles-of-the-upper-limb-in-healthy-and-post-stroke-individuals
#10
Laura Miller McPherson, Francesco Negro, Chris K Thompson, Laura Sanchez, C J Heckman, Jules Dewald, Dario Farina
Spectral analysis of surface electromyograms (sEMG) is often used to estimate central and peripheral characteristics of a motor unit (MU) population, such as average conduction velocity, proportion of muscle fiber types, and pattern of MU recruitment. This estimation is based on the assumption that the sEMG adequately reflects the frequency characteristics of the underlying MU action potentials (MUAP). However, sEMG has limitations in this respect, based on physiological and non-physiological factors that influence its frequency content...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28263283/running-technique-is-an-important-component-of-running-economy-and-performance
#11
Jonathan P Folland, Sam J Allen, Matthew I Black, Joseph C Handsaker, Stephanie E Forrester
Despite an intuitive relationship between technique and both running economy (RE) and performance, and the diverse techniques employed by runners to achieve forward locomotion, the objective importance of overall technique and the key components therein remain to be elucidated. PURPOSE: To determine the relationship between individual and combined kinematic measures of technique with both RE and performance. METHODS: Ninety-seven endurance runners (47 female) of diverse competitive standards performed a discontinuous protocol of incremental treadmill running (4 min stages, 1 km...
March 3, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28259239/long-term-comparative-outcomes-of-patients-with-peripheral-artery-disease-with-and-without-concomitant-coronary-artery-disease
#12
Debbie C Chen, Gagan D Singh, Ehrin J Armstrong, Stephen W Waldo, John R Laird, Ezra A Amsterdam
There are limited contemporary data on guideline-directed medical therapy (GDMT) utilization and long-term clinical outcomes in patients with peripheral artery disease (PAD) with and without concomitant coronary artery disease (CAD). From 2006 to 2013, 879 patients with claudication or critical limb ischemia (CLI) underwent diagnostic angiography or therapeutic endovascular intervention at our multidisciplinary vascular center. GDMT use was assessed at the time of angiography, and major adverse cardiovascular and cerebrovascular events (MACCE) and all-cause mortality were determined during 5 years of follow-up...
January 25, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28258891/directly-improving-the-quality-of-radiation-treatment-through-peer-review-a%C3%A2-cross-sectional-analysis-of-cancer-centers-across-a-provincial-cancer-program
#13
Julie Rouette, Eric Gutierrez, Jennifer O'Donnell, Lindsay Reddeman, Margaret Hart, Sophie Foxcroft, Gunita Mitera, Padraig Warde, Michael D Brundage
PURPOSE: To describe the outcomes of peer review across all 14 cancer centers in Ontario. METHODS AND MATERIALS: We identified all peer-reviewed, curative treatment plans delivered in Ontario within a 3-month study period from 2013 to 2014 using a provincial cancer treatment database and collected additional data on the peer-review outcomes. RESULTS: Considerable variation was found in the proportion of peer-reviewed plans across the centers (average 70...
October 20, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28249791/an-evaluation-of-forearm-deformities-in-hereditary-multiple-exostoses-factors-associated-with-radial-head-dislocation-and-comprehensive-classification
#14
Ah Reum Jo, Sung Taek Jung, Myung Sun Kim, Chang Seon Oh, Byung Ju Min
PURPOSE: This study attempted to evaluate a series of patients with hereditary multiple exostoses (HME) who could not be categorized according to the widely accepted Masada classification and to identify radiographic variables such as radial bowing, ulnar shortening, ulnar variance, radial articular angle, and carpal slip predictive of deformity. METHODS: We retrospectively reviewed data on 102 upper limbs of 53 pediatric patients with HME. Demographics, site of forearm involvement, and radiographic parameters were documented...
February 27, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28242396/aggressive-wound-care-by-a-multidisciplinary-team-improves-wound-healing-after-infrainguinal-bypass-in-patients-with-critical-limb-ischemia
#15
Shinsuke Mii, Kiyoshi Tanaka, Ryoichi Kyuragi, Hiroshi Ishimura, Shinsuke Yasukawa, Atsushi Guntani, Eisuke Kawakubo
BACKGROUND: A long period is generally required for ischemic ulcer to heal after revascularization. The strategy of postoperative wound care can affect wound healing. This study was conducted to investigate the degree to which aggressive wound care (AWC) by a team of multidisciplinary specialists actually shortens the time to wound healing and increases the rate of wound healing in limbs undergoing surgical bypass for ischemic tissue loss in a real clinical setting. METHODS: A total of consecutive 126 patients undergoing infrainguinal bypass for tissue loss from April 2011 to March 2015 were reviewed...
February 24, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28238406/the-effect-of-trauma-on-neanderthal-culture-a-mathematical-analysis
#16
W Nakahashi
Traumatic lesions are often observed in ancient skeletal remains. Since ancient medical technology was immature, severely traumatized individuals may have frequently lost the physical ability for cultural skills that demand complex body movements. I develop a mathematical model to analyze the effect of trauma on cultural transmission and apply it to Neanderthal culture using Neanderthal fossil data. I estimate from the data that the proportion of adult individuals who suffered traumatic injuries before death was approximately 0...
February 4, 2017: Homo: Internationale Zeitschrift Für die Vergleichende Forschung Am Menschen
https://www.readbyqxmd.com/read/28236917/outcomes-of-native-superficial-femoral-artery-chronic-total-occlusion-recanalization-after-failed-femoropopliteal-bypass
#17
Mark G Davies, Hosam F El-Sayed
OBJECTIVE: When a bypass fails, the options are lysis, redo bypass, or endovascular intervention. If lysis of the original bypass is not considered an option, which is better-redo bypass or attempts at endovascular recanalization of the native system? This retrospective study examined the outcomes of native superficial femoral artery (SFA) chronic total occlusion (CTO) recanalization compared with redo bypass after failed femoropopliteal bypass. METHODS: Patients presenting with a symptomatic failed femoropopliteal bypass that underwent attempted CTO endovascular (EV) recanalization of the native SFA or a redo femoropopliteal bypass (BP) from 2000 to 2015 were analyzed...
March 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28226506/properties-of-the-motor-unit-action-potential-shape-in-proximal-and-distal-muscles-of-the-upper-limb-in-healthy-and-post-stroke-individuals
#18
Laura Miller McPherson, Francesco Negro, Chris K Thompson, Laura Sanchez, C J Heckman, Jules Dewald, Dario Farina, Laura Miller McPherson, Francesco Negro, Chris K Thompson, Laura Sanchez, C J Heckman, Jules Dewald, Dario Farina, Chris K Thompson, Laura Miller McPherson, Laura Sanchez, Cj Heckman, Jules Dewald, Dario Farina, Francesco Negro
Spectral analysis of surface electromyograms (sEMG) is often used to estimate central and peripheral characteristics of a motor unit (MU) population, such as average conduction velocity, proportion of muscle fiber types, and pattern of MU recruitment. This estimation is based on the assumption that the sEMG adequately reflects the frequency characteristics of the underlying MU action potentials (MUAP). However, sEMG has limitations in this respect, based on physiological and non-physiological factors that influence its frequency content...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224708/out-on-a-limb-bandicoot-limb-co-variation-suggests-complex-impacts-of-development-and-adaptation-on-marsupial-forelimb-evolution
#19
Kathleen Garland, Ariel Marcy, Emma Sherratt, Vera Weisbecker
Marsupials display far less forelimb diversity than placentals, possibly because of the laborious forelimb-powered climb to the pouch performed by most marsupial neonates. This is thought to result in stronger morphological integration (i.e., higher co-variance) within the marsupial forelimb skeleton, and lower integration between marsupial fore- and hind limbs, compared to other mammals. Possible mechanisms for this constraint are a fundamental developmental change in marsupial limb patterning, or alternatively more immediate perinatal biomechanical and metabolic requirements...
February 22, 2017: Evolution & Development
https://www.readbyqxmd.com/read/28224443/report-of-the-clinical-and-functional-primary-outcomes-in-men-of-the-acl-sports-trial-similar-outcomes-in-men-receiving-secondary-prevention-with-and-without-perturbation-training-1-and-2-years-after-acl-reconstruction
#20
Amelia J H Arundale, Kathleen Cummer, Jacob J Capin, Ryan Zarzycki, Lynn Snyder-Mackler
BACKGROUND: Athletes often are cleared to return to activities 6 months after anterior cruciate ligament (ACL) reconstruction; however, knee function measures continue to improve up to 2 years after surgery. Interventions beyond standard care may facilitate successful return to preinjury activities and improve functional outcomes. Perturbation training has been used in nonoperative ACL injury and preoperative ACL reconstruction rehabilitation, but has not been examined in postoperative ACL reconstruction rehabilitation, specifically return to sport rehabilitation...
February 21, 2017: Clinical Orthopaedics and related Research
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