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Limb proportion

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https://www.readbyqxmd.com/read/29032905/analysis-of-wound-healing-time-and-wound-free-period-as-outcomes-after-surgical-and-endovascular-revascularization-for-critical-lower-limb-ischemia
#1
Jin Okazaki, Daisuke Matsuda, Kiyoshi Tanaka, Masaru Ishida, Sosei Kuma, Koichi Morisaki, Tadashi Furuyama, Yoshihiko Maehara
BACKGROUND: Traditional end points, such as amputation-free survival, used to assess the clinical effectiveness of lower limb revascularization have shortcomings because they do not account independently for wound nonhealing and recurrence or patient survival. Wound healing process and maintenance of a wound-free state after revascularization were not well-studied. The aim of this study was to elucidate the long-term clinical course of ischemic wounds after revascularization. We focused on initial wound healing process as well as the maintenance of a wound-free state after achievement of wound healing...
October 9, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29026385/a-randomized-controlled-trial-to-assess-the-effect-of-a-ketamine-infusion-on-tourniquet-hypertension-during-general-anaesthesia-in-patients-undergoing-upper-and-lower-limb-surgery
#2
Joyce Ongaya, Vitalis Mung'ayi, Thikra Sharif, Jimmie Kabugi
BACKGROUND: Tourniquet hypertension arising from tourniquet inflation remains a primary concern to the anaesthetist. One drug commonly used to manage tourniquet hypertension is ketamine. No studies have examined the effect of ketamine on tourniquet hypertension for a period of more than one hour or an infusion of the same. OBJECTIVE: To compare the effect of an intravenous infusion of ketamine versus placebo on tourniquet induced hypertension in patients undergoing upper and lower limb surgery under general anaesthesia...
March 2017: African Health Sciences
https://www.readbyqxmd.com/read/29025427/adaptive-hybrid-robotic-system-for-rehabilitation-of-reaching-movement-after-a-brain-injury-a-usability-study
#3
F Resquín, J Gonzalez-Vargas, J Ibáñez, F Brunetti, I Dimbwadyo, L Carrasco, S Alves, C Gonzalez-Alted, A Gomez-Blanco, J L Pons
BACKGROUND: Brain injury survivors often present upper-limb motor impairment affecting the execution of functional activities such as reaching. A currently active research line seeking to maximize upper-limb motor recovery after a brain injury, deals with the combined use of functional electrical stimulation (FES) and mechanical supporting devices, in what has been previously termed hybrid robotic systems. This study evaluates from the technical and clinical perspectives the usability of an integrated hybrid robotic system for the rehabilitation of upper-limb reaching movements after a brain lesion affecting the motor function...
October 12, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28992180/integrating-evo-and-devo-the-limb-as-model-structure
#4
Nathan M Young
Reconciling the origins of morphological diversity with the deep homology of underlying mechanisms is a question fundamental to the goals of evolutionary developmental biology ("evo-devo" or EDB). In this paper I argue that differing research agendas in evolutionary and developmental biology have hindered how we address this question, but that the limb provides ideal "common ground" for their fuller integration. To support this idea, I review two previous analyses of limb variation in mammal, bird, and reptile taxa that offer complementary approaches to explaining diversity...
September 6, 2017: Integrative and Comparative Biology
https://www.readbyqxmd.com/read/28990491/young-athletes-after-anterior-cruciate-ligament-reconstruction-cleared-for-sports-participation-how-many-actually-meet-recommended-return-to-sport-criteria-cutoffs
#5
Allison R Toole, Matthew P Ithurburn, Mitchell J Rauh, Timothy E Hewett, Mark V Paterno, Laura C Schmitt
Study Design Prospective cohort study. Background While meeting objective criteria cutoffs are recommended prior to return-to-sport (RTS) following ACL reconstruction (ACLR), the number of young athletes meeting recommended cutoffs and their impact on longitudinal sports participation are unknown. Objectives To test the hypothesis that a higher proportion of young athletes who met recommended cutoffs would maintain the same level of sports participation over the year following RTS clearance compared to those who did not...
October 7, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28988268/epidemiology-of-dance-related-injuries-presenting-to-emergency-departments-in-the-united-states-2000-2013
#6
Amy J Vassallo, Claire Hiller, Emmanuel Stamatakis, Evangelos Pappas
Dance is a popular activity associated with many physical and mental health benefits, but injuries are a concern for all skill levels. Previous studies have focused on professional dancers or particular genres, meaning the population-wide characteristics of injuries is unknown. This study's objective was to identify the incidence and types of dance-related injuries evaluated in emergency departments in the United States over the 14-year period 2000-2013. METHODS: Data were obtained from the nationally representative National Electronic Injury Surveillance System from 2000-2013...
September 2017: Medical Problems of Performing Artists
https://www.readbyqxmd.com/read/28987672/volume-fractions-of-dce-mri-parameter-as-early-predictor-of-histologic-response-in-soft-tissue-sarcoma-a-feasibility-study
#7
Wei Xia, Zhuangzhi Yan, Xin Gao
OBJECTIVE: To find early predictors of histologic response in soft tissue sarcoma through volume transfer constant (K(trans)) analysis based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). MATERIALS AND METHODS: 11 Patients with soft tissue sarcoma of the lower extremity that underwent preoperative chemoradiotherapy followed by limb salvage surgery were included in this retrospective study. For each patient, DCE-MRI data sets were collected before and two weeks after therapy initiation, and histologic tumor cell necrosis rate (TCNR) was reported at surgery...
October 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28983219/reliability-and-reproducibility-of-subject-positioning-with-eos-low-dose-biplanar-x-ray
#8
Christine Goodbody, Paz Kedem, Michaela Thompson, Huong T Do, Douglas N Mintz, Roger F Widmann, Emily R Dodwell
BACKGROUND: EOS low-dose biplanar X-ray used with tantalum bead implantation is an appealing imaging modality to evaluate limb length and physeal growth due its relatively low radiation exposure, excellent inter- and intra-observer reliability, and minimal magnification/shrinkage error. QUESTIONS/PURPOSES: The purpose of this study was to establish the error in total length and inter-bead distances using EOS and tantalum beads due to variable positioning in the EOS gantry, by assessing variation in measurements made on the same subject repeatedly positioning by one positioner (intra-positioner measurement error) and variation in measurements made on the same subject with positioning by multiple positioners (inter-positioner measurement error)...
October 2017: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://www.readbyqxmd.com/read/28978866/two-year-clinical-outcomes-post-implantation-of-epic-tm-self-expanding-nitinol-stents-for-the-aortoiliac-occlusive-disease-in-patients-with-peripheral-arterial-disease
#9
Takuya Tsujimura, Osamu Iida, Masashi Fujita, Masaharu Masuda, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Takashi Kanda, Shota Okuno, Yasuhiro Matsuda, Masahiko Fujihara, Yoshiaki Yokoi, Toshiaki Mano
AIM: We investigated 2-year clinical outcomes after implantaton of Epic(TM) self-expanding nitinol stents for patients with peripheral artery disease (PAD) due to the aortoiliac occlusive disease (AIOD). METHODS: This study was a multicenter and retrospective study. From February 2013 through October 2014, 292 lesions (chronic total occlusion, 21%; TASC Ⅱ C/D, 35%) in 217 consecutive patients (74±8 years; male, 81%; diabetes mellitus, 47%; dialysis, 21%; critical limb ischemia, 29%) who had undergone endovascular therapy (EVT) with Epic(TM) self-expanding nitinol stents for PAD with AIOD were analyzed...
October 5, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/28977603/androgen-action-via-the-androgen-receptor-in-neurons-within-the-brain-positively-regulates-muscle-mass-in-male-mice
#10
Rachel A Davey, Michele V Clarke, Patricia K Russell, Kesha Rana, Jane Seto, Kelly N Roeszler, Jackie M Y How, Ling Yeong Chia, Kathryn North, Jeffrey D Zajac
Although it is well established that exogenous androgens have anabolic effects on skeletal muscle mass in humans and mice, data from muscle-specific androgen receptor (AR) knockout (ARKO) mice indicate that myocytic expression of the AR is dispensable for hind-limb muscle mass accrual in males. To identify possible indirect actions of androgens via the AR in neurons to regulate muscle, we generated neuron-ARKO mice in which the dominant DNA binding-dependent actions of the AR are deleted in neurons of the cortex, forebrain, hypothalamus, and olfactory bulb...
October 1, 2017: Endocrinology
https://www.readbyqxmd.com/read/28977598/rac1-dosage-is-crucial-for-normal-endochondral-bone-growth
#11
Dai Suzuki, Jason R Bush, Dawn-Marie Bryce, Ryutaro Kamijo, Frank Beier
Rac1, a member of the small Rho GTPase family, plays multiple cellular roles. Studies of mice conditionally lacking Rac1 have revealed essential roles for Rac1 in various tissues, including cartilage and limb mesenchyme, where Rac1 loss produces dwarfism and long bone shortening. To gain further insight into the role of Rac1 in skeletal development, we have used transgenic mouse lines to express a constitutively active (ca) Rac1 mutant protein in a Cre recombinase-dependent manner. Overexpression of caRac1 in limb bud mesenchyme or chondrocytes leads to reduced body weight and shorter bones compared with control mice...
October 1, 2017: Endocrinology
https://www.readbyqxmd.com/read/28974400/the-effect-of-knee-flexor-and-extensor-fatigue-on-shock-absorption-during-cutting-movements-after-a-jump-landing
#12
Youkyung Kim, Changhong Youm, Minji Son, Jinhee Kim, Myeounggon Lee
BACKGROUND: Sporting situations include instances of continuous and/or integrated movements. However, the effect of fatigue on the performance of these movements remains unclear. PURPOSE: To investigate the effect of knee flexor and extensor fatigue on the shock absorption strategy of the lower limb during cutting movements performed after jump landings. METHODS: Twenty-four healthy participants performed cutting movements following jump landings from two heights - 30cm and 40cm - and under three levels of lower limb fatigue: pre-fatigue (100% peak knee extension torque), and post-fatigue 50% (post-50%) and 30% (post-30%) peak knee extension torque...
September 30, 2017: Knee
https://www.readbyqxmd.com/read/28964919/prospective-assessment-of-patients-knowledge-and-informational-needs-and-of-surgeon-to-patient-information-transfer-before-and-after-knee-or-hip-arthroplasty
#13
L Billon, B Dcaudin, G Pasquier, A Lons, V Deken-Delannoy, A-F Germe, P Odou, H Migaud
BACKGROUND: Patients are playing an increasingly large role in their own management and must therefore receive clear, complete, and comprehensible information. In the field of hip and knee arthroplasty, little is known about the level of patient knowledge and effectiveness of surgeon-to-patient information transfer. We therefore designed a prospective observational study with the objective of assessing four factors: patient knowledge during management, quality of information transfer, informational needs, and factors associated with the level of knowledge...
September 27, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28963153/do-varus-or-valgus-outliers-have-higher-forces-in-the-medial-or-lateral-compartments-than-those-which-are-in-range-after-a-kinematically-aligned-total-knee-arthroplasty-limb-and-joint-line-alignment-after-kinematically-aligned-total-knee-arthroplasty
#14
T J Shelton, A J Nedopil, S M Howell, M L Hull
AIMS: The aims of this study were to determine the proportion of patients with outlier varus or valgus alignment in kinematically aligned total knee arthroplasty (TKA), whether those with outlier varus or valgus alignment have higher forces in the medial or lateral compartments of the knee than those with in-range alignment and whether measurements of the alignment of the limb, knee and components predict compartment forces. PATIENTS AND METHODS: The intra-operative forces in the medial and lateral compartments were measured with an instrumented tibial insert in 67 patients who underwent a kinematically aligned TKA during passive movement...
October 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28952193/lymphatic-mapping-of-the-upper-limb-with-lymphedema-before-lymphatic-supermicrosurgery-by-mirroring-of-the-healthy-limb
#15
Stefano Gentileschi, Maria Servillo, Roberta Albanese, Francesca De Bonis, Girolamo Tartaglione, Marzia Salgarello
INTRODUCTION: Supermicrosurgical lymphatic-venous anastomosis (LVA) can improve limbs lymphedema. We describe a technique that we employ for preoperative lymphatic mapping of the upper limb (UL), when indocyanine green (ICG) lymphography shows only dermal backflow (DB) and no lymphatic vessel is detectable. PATIENTS AND METHODS: Sixteen patients undergoing LVA for unilateral UL lymphedema, showing "stardust" or "diffuse" DB pattern, were included. Demographic, clinical data, and limbs measurements were recorded...
September 27, 2017: Microsurgery
https://www.readbyqxmd.com/read/28951440/a-sports-based-youth-development-program-teen-mental-health-and-physical-fitness-an-rct
#16
RANDOMIZED CONTROLLED TRIAL
Frederick Ka Wing Ho, Lobo Hung Tak Louie, Wilfred Hing-Sang Wong, Ko Ling Chan, Agnes Tiwari, Chun Bong Chow, Walter Ho, William Wong, Meanne Chan, Eric Yu Hai Chen, Yiu Fai Cheung, Patrick Ip
OBJECTIVES: To assess the effectiveness of a positive youth development (PYD)-based sports mentorship program on the physical and mental well-being of adolescents recruited in a community setting. METHODS: This is a randomized controlled trial in which we recruited students from 12 secondary schools in Hong Kong, China. Participants were randomly assigned in a 1:1 ratio to an intervention or a control arm after stratification for school from October 2013 to June 2014...
October 2017: Pediatrics
https://www.readbyqxmd.com/read/28951156/black-patients-present-with-more-severe-vascular-disease-and-a-greater-burden-of-risk-factors-than-white-patients-at-time-of-major-vascular-intervention
#17
Peter A Soden, Sara L Zettervall, Sarah E Deery, Kakra Hughes, Michael C Stoner, Philip P Goodney, Ageliki G Vouyouka, Marc L Schermerhorn
BACKGROUND: Although many studies have demonstrated racial disparities after major vascular surgery, few have identified the reasons for these disparities, and those that did often lacked clinical granularity. Therefore, our aim was to evaluate differences in initial vascular intervention between black and white patients. METHODS: We identified black and white patients' initial carotid, abdominal aortic aneurysm (AAA), and infrainguinal peripheral artery disease (PAD) interventions in the Vascular Quality Initiative (VQI) registry from 2009 to 2014...
September 23, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28951009/a-retrospective-cohort-study-to-assess-adjuvant-concurrent-chemoradiation-ccrt-compared-to-adjuvant-radiation-therapy-rt-in-the-treatment-of-grade-2-and-3-extremity-soft-tissue-sarcomas
#18
Jean Philippe Nesseler, Julia Salleron, Maria Rios, Philippe Nickers, Frederic Marchal, Fabien Brocard, Didier Peiffert, Guillaume Vogin
PURPOSE: To evaluate the efficacy and tolerance of adjuvant concurrent chemoradiation (CCRT) as treatment of grade 2 and 3 (G2-3) localized extremity soft tissue sarcomas (STS) by comparing CCRT with standard adjuvant radiation therapy (RT). PATIENTS AND METHODS: This monocentric retrospective study included non-pediatric patients (>16years) treated by adjuvant RT with or without chemotherapy (CT) after conservative resection of non-recurrent G2-3 extremity STS...
September 23, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28940152/osteomyelitis-risk-in-patients-with-transfemoral-amputations-treated-with-osseointegration-prostheses
#19
Jonatan Tillander, Kerstin Hagberg, Örjan Berlin, Lars Hagberg, Rickard Brånemark
BACKGROUND: Percutaneous anchoring of femoral amputation prostheses using osseointegrating titanium implants has been in use for more than 25 years. The method offers considerable advantages in daily life compared with conventional socket prostheses, however long-term success might be jeopardized by implant-associated infection, especially osteomyelitis, but the long-term risk of this complication is unknown. QUESTIONS/PURPOSES: (1) To quantify the risk of osteomyelitis, (2) to characterize the clinical effect of osteomyelitis (including risk of implant extraction and impairments to function), and (3) to determine whether common patient factors (age, sex, body weight, diabetes, and implant component replacements) are associated with osteomyelitis in patients with transfemoral amputations treated with osseointegrated titanium implants...
September 22, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28938392/segmental-bone-loss-reconstruction-using-ring-fixation
#20
Stephen M Quinnan
Ring fixation is a powerful tool in the treatment of bone defects. The ability to create high-quality, biologically normal new bone of even massive proportions using distraction osteogenesis is a major reason for its success. In addition, ring fixation provides the ability to limit the risk of deep infection, improves flexibility in limb length control and alignment, and increases soft tissue coverage options. The drawbacks of ring fixation include long frame times, pin problems, risk of joint contractures, and difficult usage in areas with a large soft tissue envelope such as the thigh...
October 2017: Journal of Orthopaedic Trauma
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