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Developmental science

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https://www.readbyqxmd.com/read/28095647/new-generation-mass-spectrometry-expands-the-toolbox-of-cell-and-developmental-biology
#1
REVIEW
Camille Lombard-Banek, Erika P Portero, Rosemary M Onjiko, Peter Nemes
Systems cell biology understanding of development requires characterization of all the molecules produced in the biological system. Decades of research and new-generation sequencing provided functional information on key genes and transcripts. However, there is less information available on how differential gene expression translates into the domains of functionally important proteins, peptides, and metabolites, and how changes in these molecules impact development. Mass spectrometry (MS) is the current technology of choice for the detection and quantification of large numbers of proteins and metabolites, because it requires no use of antibodies, functional probes, or a priori knowledge of molecules produced in the system...
January 17, 2017: Genesis: the Journal of Genetics and Development
https://www.readbyqxmd.com/read/28079529/leveraging-the-skills-of-nurses-and-the-power-of-language-nutrition-to-ensure-a-better-future-for-children
#2
Ashley Darcy Mahoney, Lauren Head Zauche, Sunny Hallowell, Arianne Weldon, Jennifer Stapel-Wax
BACKGROUND: Early language exposure is critical for language acquisition and significantly influences a child's literacy skills. However, preterm infants may experience language deprivation in the neonatal intensive care unit. Nurses are vital to helping parents understand their critical role in early language development. PURPOSE: To discuss the impact of language-rich interactions and interventions that promote early language exposure, or Language Nutrition, by parents and caregivers on the long-term developmental, language, and educational outcomes of high-risk infants...
January 11, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28067083/-examination-of-psychomotor-development-in-relation-to-social-environmental-factors-in-preterm-children-at-2-years-old
#3
Flóra Kenyhercz, Beáta Nagy
INTRODUCTION: The development of children born prematurely is an important aspect in public health, because preterm birth rates are not decreasing with the development of medical sciences. AIM: Description of psychomotor development of preterm children related to potentially influencing environmental factors. METHOD: Children born below 2.500 grams at the age of two (n = 75). Psychomotor development, quality of home environment, socio-demographic background were measured...
January 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28065192/cognition-and-culture-in-evolutionary-context
#4
Fernando Colmenares, María Victoria Hernández-Lloreda
In humans and other animals, the individuals' ability to adapt efficiently and effectively to the niches they have actively contributed to construct relies heavily on an evolved psychology which has been shaped by biological, social, and cultural processes over evolutionary time. As expected, although many of the behavioral and cognitive components of this evolved psychology are widely shared across species, many others are species-unique. Although many animal species are known to acquire group-specific traditions (or cultures) via social learning, human culture is unique in terms of its contents and characteristics (observable and unobservable products, cumulative effects, norm conformity, and norm enforcement) and of its cognitive underpinnings (imitation, instructed teaching, and language)...
January 9, 2017: Spanish Journal of Psychology
https://www.readbyqxmd.com/read/28060300/kinematic-analysis-of-cell-division-and-expansion-quantifying-the-cellular-basis-of-growth-and-sampling-developmental-zones-in-zea-mays-leaves
#5
Katrien Sprangers, Viktoriya Avramova, Gerrit T S Beemster
Growth analyses are often used in plant science to investigate contrasting genotypes and the effect of environmental conditions. The cellular aspect of these analyses is of crucial importance, because growth is driven by cell division and cell elongation. Kinematic analysis represents a methodology to quantify these two processes. Moreover, this technique is easy to use in non-specialized laboratories. Here, we present a protocol for performing a kinematic analysis in monocotyledonous maize (Zea mays) leaves...
December 2, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28042900/severe-youth-violence-developmental-perspectives-introduction-to-the-special-section
#6
Tina Malti, Margit Averdijk
In this article, the authors introduce the special section on severe youth violence (SYV). As severe violence has significant negative consequences and youth commit more violence than other age groups, a developmental science approach is important to (a) understand pathways to SYV, (b) guide attempts to screen and assess SYV risk, and (c) inform novel, developmentally sensitive practices and policies to prevent and reduce SYV. The authors establish the theoretical and empirical contexts for the articles in this special section and explain how this developmental research on SYV can inform new lines of theoretical and empirical inquiry and innovative approaches to detect and respond to the risk of SYV...
January 2017: Child Development
https://www.readbyqxmd.com/read/28032479/the-role-of-nutrition-in-integrated-early-child-development-in-the-21st-century-contribution-from-the-maternal-and-child-nutrition-journal
#7
EDITORIAL
Rafael Pérez-Escamilla, Victoria Hall Moran
Even though it is widely recognized that early childhood development (ECD) is one of the most important predictors of future social capital and national productivity, the recently published ECD Lancet Series reports that about 250 million children under 5 years are at risk of not reaching their developmental potential, mainly as a result of poverty and social injustice. So why is this and what will it take to reverse this situation? The purpose of this special issue is to highlight important contributions from previously published articles in Maternal & Child Nutrition to the field of nutrition and ECD...
January 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/28026188/editorial
#8
Eric F Dubow
Developmental Psychology (DP) has long been in the forefront of shaping the field of life span developmental science by advancing theory, research design, and statistical methodology and applying these to timely topics. My overarching goal as editor is to ensure that DP continues to play a leading role in charting the future of developmental science research by maintaining the highest theoretical and methodological standards and to further extend our reach by continuing to encourage international and multidisciplinary researchers to submit manuscripts...
January 2017: Developmental Psychology
https://www.readbyqxmd.com/read/28024174/biology-meets-physics-reductionism-and-multi-scale-modeling-of-morphogenesis
#9
Sara Green, Robert Batterman
A common reductionist assumption is that macro-scale behaviors can be described "bottom-up" if only sufficient details about lower-scale processes are available. The view that an "ideal" or "fundamental" physics would be sufficient to explain all macro-scale phenomena has been met with criticism from philosophers of biology. Specifically, scholars have pointed to the impossibility of deducing biological explanations from physical ones, and to the irreducible nature of distinctively biological processes such as gene regulation and evolution...
December 23, 2016: Studies in History and Philosophy of Biological and Biomedical Sciences
https://www.readbyqxmd.com/read/27989988/novel-mutations-and-structural-deletions-in-tubb8-expanding-mutational-and-phenotypic-spectrum-of-patients-with-arrest-in-oocyte-maturation-fertilization-or-early-embryonic-development
#10
Biaobang Chen, Bin Li, Da Li, Zheng Yan, Xiaoyan Mao, Yao Xu, Jian Mu, Qiaoli Li, Li Jin, Lin He, Yanping Kuang, Qing Sang, Lei Wang
STUDY QUESTION: Are there any new type of mutations and novel phenotypes in patients with arrest in oocyte maturation, fertilization or early embryonic development having tubulin beta eight class VIII (TUBB8) mutations? SUMMARY ANSWER: We identified new types of mutations in TUBB8 associated with maturation, fertilization and developmental arrest. WHAT IS KNOWN ALREADY: We previously found heterozygous mutations and a homozygous frameshift/internal seven amino acid deletion in TUBB8 that are responsible for oocyte maturation arrest...
December 17, 2016: Human Reproduction
https://www.readbyqxmd.com/read/27979632/cortisol-and-dhea-in-development-and-psychopathology
#11
REVIEW
Hayley S Kamin, Darlene A Kertes
Dehydroepiandrosterone (DHEA) and cortisol are the most abundant hormones of the human fetal and adult adrenals released as end products of a tightly coordinated endocrine response to stress. Together, they mediate short- and long-term stress responses and enable physiological and behavioral adjustments necessary for maintaining homeostasis. Detrimental effects of chronic or repeated elevations in cortisol on behavioral and emotional health are well documented. Evidence for actions of DHEA that offset or oppose those of cortisol has stimulated interest in examining their levels as a ratio, as an alternate index of adrenocortical activity and the net effects of cortisol...
December 12, 2016: Hormones and Behavior
https://www.readbyqxmd.com/read/27968870/developmental-profile-of-ocular-refraction-in-patients-with-congenital-cataract-a-prospective-cohort-study
#12
Zhenzhen Liu, Erping Long, Jingjing Chen, Zhuoling Lin, Duoru Lin, Xiaohang Wu, Qianzhong Cao, Xiaoyan Li, Dongni Wang, Lixia Luo, Bo Qu, Runzhong Liu, Xiaopin Liu, Haotian Lin, Weirong Chen, Yizhi Liu
BACKGROUND: Refractive status is crucial to visual function and can change throughout life. For patients with congenital cataract, the developmental profile of refraction is complicated owing to the potential influence of diverse clinical manifestations and various treatments, and has not yet been fully characterised. METHODS: In this prospective cohort study, we enrolled patients with congenital cataract from the Childhood Cataract Program of the Chinese Ministry of Health (CCPMOH)...
October 2016: Lancet
https://www.readbyqxmd.com/read/27968824/relationships-between-physicians-psychological-contract-and-job-satisfaction-intention-to-leave-medical-practice-and-professionalism-a-cross-sectional-survey-in-china
#13
Zhou Ping, Shi Jian-Wei, Zhang Yu, Bai Fei, Wei Xue-Feng, Xue Di
BACKGROUND: Physician motivation to maintain public welfare has become the key for the New Public Hospital Reform in China. This study aimed to apply a different perspective, the psychological contract (a popular concept in business management research) and explore the correlations between physicians' psychological contract and their job satisfaction, intention to leave medical practice, and professionalism. METHODS: A cross-sectional survey was conducted using a stratified sampling method in Shanghai, Hubei, and Gansu in China from June 10 to October 30, 2013...
October 2016: Lancet
https://www.readbyqxmd.com/read/27957444/a-novel-mutation-in-the-ofd1-gene-in-a-family-with-oral-facial-digital-syndrome-type-1-a-case-report
#14
Masoud Dehghan Tezerjani, Reza Maroofian, Mohammad Yahya Vahidi Mehrjardi, Barry A Chioza, Shiva Zamaninejad, Seyed Mehdi Kalantar, Mahmoud Nori-Shadkam, Hamidreza Ghadimi, Emma L Baple, Andrew H Crosby, Mohammadreza Dehghani
Oral-facial-digital syndrome as heterogeneous developmental conditions is characterized by abnormalities in the oral cavity, facial features and digits. Furthermore, central nervous system (CNS) abnormalities can also be part of this developmental disorder. At least 13 forms of OFDS based on their pattern of signs and symptoms have been identified so far. Type 1 which is now considered to be a ciliopathy accounts for the majority of cases. It is transmitted in an X-linked dominant pattern and caused by mutations in OFD1 gene, which can result in embryonic male lethality...
October 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/27957258/prevalence-and-distribution-of-selected-dental-anomalies-among-saudi-children-in-abha-saudi-arabia
#15
Syed M Yassin
BACKGROUND: Dental anomalies are not an unusual finding in routine dental examination. The effect of dental anomalies can lead to functional, esthetic and occlusal problems. The Purpose of the study was to determine the prevalence and distribution of selected developmental dental anomalies in Saudi children. MATERIAL AND METHODS: The study was based on clinical examination and Panoramic radiographs of children who visited the Pediatric dentistry clinics at King Khalid University College of Dentistry, Saudi Arabia...
December 2016: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/27943323/i-executive-control-in-early-childhood
#16
C A C Clark, N Chevalier, J M Nelson, T D James, J P Garza, H-J Choi, K A Espy
Executive control (EC) is a central construct in developmental science, although measurement limitations have hindered understanding of its nature and development in young children, relation to social risk, and prediction of important outcomes. Disentangling EC from the foundational cognitive abilities it regulates and that are inherently required for successful executive task completion (e.g., language, visual/spatial perception, and motor abilities) is particularly challenging at preschool age, when these foundational abilities are still developing and consequently differ substantially among children...
December 2016: Monographs of the Society for Research in Child Development
https://www.readbyqxmd.com/read/27942087/twenty-first-century-macro-trends-in-the-institutional-fabric-of-science-bibliometric-monitoring-and-analysis
#17
Robert J W Tijssen, Jos Winnink
Some say that world science has become more 'applied', or at least more 'application-oriented', in recent years. Replacing the ill-defined distinction between 'basic research' and 'applied research', we introduce 'research application orientation' domains as an alternative conceptual and analytical framework for examining research output growth patterns. To distinguish possible developmental trajectories we define three institutional domains: 'university', 'industry', 'hospitals'. Our macro-level bibliometric analysis takes a closer look at general trends within and across some 750 of the world's largest research-intensive universities...
2016: Scientometrics
https://www.readbyqxmd.com/read/27939721/a-bioenergetics-assay-for-studying-the-effects-of-environmental-stressors-on-mitochondrial-function-in-vivo-in-zebrafish-larvae
#18
Tara D Raftery, Nishad Jayasundara, Richard T Di Giulio
Mitochondria, an integral component of cellular energy metabolism and other key functions, are extremely vulnerable to damage by environmental stressors. Although methods to measure mitochondrial function in vitro exist, sensitive, medium- to high-throughput assays that assess respiration within physiologically-relevant whole organisms are needed to identify drugs and/or chemicals that disrupt mitochondrial function, particularly at sensitive early developmental stages. Consequently, we have developed and optimized an assay to measure mitochondrial bioenergetics in zebrafish larvae using the XF(e)24 Extracellular Flux Analyzer...
February 2017: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP
https://www.readbyqxmd.com/read/27938597/-diagnosis-of-a-case-with-williams-beuren-syndrome-with-nephrocalcinosis-using-chromosome-microarray-analysis
#19
S J Jin, M Liu, W J Long, X P Luo
Objective: To explore the clinical phenotypes and the genetic cause for a boy with unexplained growth retardation, nephrocalcinosis, auditory anomalies and multi-organ/system developmental disorders. Method: Routine G-banding and chromosome microarray analysis were applied to a child with unexplained growth retardation, nephrocalcinosis, auditory anomalies and multi-organ/system developmental disorders treated in the Department of Pediatrics of Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology in September 2015 and his parents to conduct the chromosomal karyotype analysis and the whole genome scanning...
December 2, 2016: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/27929318/family-involvement-and-parent-teacher-relationships-for-students-with-autism-spectrum-disorders
#20
S Andrew Garbacz, Laura Lee McIntyre, Rachel T Santiago
Family educational involvement and parent-teacher relationships are important for supporting student outcomes and have unique implications for families of children with autism spectrum disorder (ASD). However, little research has examined child and family characteristics among families of children with ASD as predictors of family involvement and parent-teacher relationships. The present study examined child and family variables that may affect family involvement and parent-teacher relationships for families of children with ASD...
December 2016: School Psychology Quarterly
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