keyword
MENU ▼
Read by QxMD icon Read
search

Developmental science

keyword
https://www.readbyqxmd.com/read/28435745/a-consult-service-to-support-and-promote-community-based-research-tracking-and-evaluating-a-community-based-research-consult-service
#1
Clara M Pelfrey, Katrice D Cain, Mary Ellen Lawless, Earl Pike, Ashwini R Sehgal
PURPOSE: This study describes the design, operation and evaluation of a community-based research (CBR) consult service within the setting of a Clinical and Translational Science Award (CTSA) institution. To our knowledge, there are no published evaluations of a CBR consult service at a CTSA hub. METHODS: A community-based research Consult Service was created to support faculty, health care providers/research coordinators, trainees, community-based organizations and community members...
February 2017: J Clin Transl Sci
https://www.readbyqxmd.com/read/28431241/akt-pkb-signaling-navigating-the-network
#2
REVIEW
Brendan D Manning, Alex Toker
The Ser and Thr kinase AKT, also known as protein kinase B (PKB), was discovered 25 years ago and has been the focus of tens of thousands of studies in diverse fields of biology and medicine. There have been many advances in our knowledge of the upstream regulatory inputs into AKT, key multifunctional downstream signaling nodes (GSK3, FoxO, mTORC1), which greatly expand the functional repertoire of AKT, and the complex circuitry of this dynamically branching and looping signaling network that is ubiquitous to nearly every cell in our body...
April 20, 2017: Cell
https://www.readbyqxmd.com/read/28427445/parasites-pathogens-and-commensals-in-the-low-impact-non-native-amphipod-host-gammarus-roeselii
#3
Jamie Bojko, Karolina Bącela-Spychalska, Paul D Stebbing, Alison M Dunn, Michał Grabowski, Michał Rachalewski, Grant D Stentiford
BACKGROUND: Whilst vastly understudied, pathogens of non-native species (NNS) are increasingly recognised as important threats to native wildlife. This study builds upon recent recommendations for improved screening for pathogens in NNS by focusing on populations of Gammarus roeselii in Chojna, north-western Poland. At this location, and in other parts of continental Europe, G. roeselii is considered a well-established and relatively 'low-impact' invader, with little understanding about its underlying pathogen profile and even less on potential spill-over of these pathogens to native species...
April 20, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28420222/how-sensors-might-help-define-the-external-exposome
#4
REVIEW
Miranda Loh, Dimosthenis Sarigiannis, Alberto Gotti, Spyros Karakitsios, Anjoeka Pronk, Eelco Kuijpers, Isabella Annesi-Maesano, Nour Baiz, Joana Madureira, Eduardo Oliveira Fernandes, Michael Jerrett, John W Cherrie
The advent of the exposome concept, the advancement of mobile technology, sensors, and the "internet of things" bring exciting opportunities to exposure science. Smartphone apps, wireless devices, the downsizing of monitoring technologies, along with lower costs for such equipment makes it possible for various aspects of exposure to be measured more easily and frequently. We discuss possibilities and lay out several criteria for using smart technologies for external exposome studies. Smart technologies are evolving quickly, and while they provide great promise for advancing exposure science, many are still in developmental stages and their use in epidemiology and risk studies must be carefully considered...
April 18, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28410120/snp_tata_comparator-genomewide-landmarks-for-preventive-personalized-medicine
#5
Mikhail Ponomarenko, Dmitry Rasskazov, Irina Chadaeva, Ekaterina Sharypova, Petr Ponomarenko, Olga Arkova, Elena Kashina, Nikita Ivanisenko, Dmitry Zhechev, Ludmila Savinkova, Nikolay Kolchanov
Year after year, conditions, quality, and duration of human lives have been improving due to the progress of science, technology, education, and medicine, which however has a downside. Owing to improvement in children's nutrition, developmental acceleration occurs that imbalances a child's system. Because of virtual worlds of the Internet, social experience of teenagers expands and clashes with puberty of adolescents. Due to the comfort of cities, urbanization emerges and causes stress to adults because of artificial light, noise, pollution, violations of personal space, and family disruption...
June 1, 2017: Frontiers in Bioscience (Scholar Edition)
https://www.readbyqxmd.com/read/28397398/proteomic-profile-of-mabuya-sp-squamata-scincidae-ovary-and-placenta-during-gestation
#6
Nathaly Hernández-Díaz, Rodrigo Torres, Martha Patricia Ramírez-Pinilla
Reptiles are one of the most diverse groups of vertebrates, providing an integrated system for comparative studies on metabolic, animal physiology, and developmental biology. However, the molecular data available are limited and only recently have started to call attention in the "omics" sciences. Mabuya sp. is a viviparous placentrotrophic skink with particular reproductive features, including microlecithal eggs, early luteolysis, prolonged gestation, and development of a highly specialized placenta. This placenta is responsible for respiratory exchange and the transference of all nutrients necessary for embryonic development...
April 11, 2017: Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution
https://www.readbyqxmd.com/read/28388275/costs-of-selective-attention-when-children-notice-what-adults-miss
#7
Daniel J Plebanek, Vladimir M Sloutsky
One of the lawlike regularities of psychological science is that of developmental progression-an increase in sensorimotor, cognitive, and social functioning from childhood to adulthood. Here, we report a rare violation of this law, a developmental reversal in attention. In Experiment 1, 4- to 5-year-olds ( n = 34) and adults ( n = 35) performed a change-detection task that included externally cued and uncued shapes. Whereas the adults outperformed the children on the cued shapes, the children outperformed the adults on the uncued shapes...
April 1, 2017: Psychological Science
https://www.readbyqxmd.com/read/28386178/support-vector-machine-based-open-crop-model-sbocm-case-of-rice-production-in-china
#8
Ying-Xue Su, Huan Xu, Li-Jiao Yan
Existing crop models produce unsatisfactory simulation results and are operationally complicated. The present study, however, demonstrated the unique advantages of statistical crop models for large-scale simulation. Using rice as the research crop, a support vector machine-based open crop model (SBOCM) was developed by integrating developmental stage and yield prediction models. Basic geographical information obtained by surface weather observation stations in China and the 1:1000000 soil database published by the Chinese Academy of Sciences were used...
March 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28379982/measuring-the-mass-volume-and-density-of-microgram-sized-objects-in-fluid
#9
Shirin Mesbah Oskui, Heran C Bhakta, Graciel Diamante, Huinan Liu, Daniel Schlenk, William H Grover
Measurements of an object's fundamental physical properties like mass, volume, and density can offer valuable insights into the composition and state of the object. However, many important biological samples reside in a liquid environment where it is difficult to accurately measure their physical properties. We show that by using a simple piece of glass tubing and some inexpensive off-the-shelf electronics, we can create a sensor that can measure the mass, volume, and density of microgram-sized biological samples in their native liquid environment...
2017: PloS One
https://www.readbyqxmd.com/read/28371859/classification-criteria-for-diffuse-idiopathic-skeletal-hyperostosis-a-lack-of-consensus
#10
Jonneke S Kuperus, Erin E A de Gendt, F Cumhur Oner, Pim A de Jong, Stan C F M Buckens, Alie E van der Merwe, George J R Maat, Elizabeth A Regan, Donald L Resnick, Reuven Mader, Jorrit-Jan Verlaan
Objectives.: DISH is a condition characterized by flowing ossifications of the spine with or without ossifications of entheses elsewhere in the body. Studies on the prevalence and pathogenesis of DISH use a variety of partly overlapping combinations of classification criteria, making meaningful comparisons across the literature difficult. The aim of this study was to systematically summarize the available criteria to support the development of a more uniform set of diagnostic/classification criteria...
March 27, 2017: Rheumatology
https://www.readbyqxmd.com/read/28366718/the-physics-of-development-100years-after-d-arcy-thompson-s-on-growth-and-form
#11
REVIEW
James Briscoe, Anna Kicheva
By applying methods and principles from the physical sciences to biological problems, D'Arcy Thompson's On Growth and Form demonstrated how mathematical reasoning reveals elegant, simple explanations for seemingly complex processes. This has had a profound influence on subsequent generations of developmental biologists. We discuss how this influence can be traced through twentieth century morphologists, embryologists and theoreticians to current research that explores the molecular and cellular mechanisms of tissue growth and patterning, including our own studies of the vertebrate neural tube...
March 30, 2017: Mechanisms of Development
https://www.readbyqxmd.com/read/28365593/development-and-dynamics-of-cell-polarity-at-a-glance
#12
REVIEW
Joseph P Campanale, Thomas Y Sun, Denise J Montell
Cells exhibit morphological and molecular asymmetries that are broadly categorized as cell polarity. The cell polarity established in early embryos prefigures the macroscopic anatomical asymmetries characteristic of adult animals. For example, eggs and early embryos have polarized distributions of RNAs and proteins that generate global anterior/posterior and dorsal/ventral axes. The molecular programs that polarize embryos are subsequently reused in multiple contexts. Epithelial cells require apical/basal polarity to establish their barrier function...
April 1, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28362435/a-guide-to-light-sheet-fluorescence-microscopy-for-multiscale-imaging
#13
Rory M Power, Jan Huisken
The impact of light-sheet fluorescence microscopy (LSFM) is visible in fields as diverse as developmental and cell biology, anatomical science, biophysics and neuroscience. Although adoption among biologists has been steady, LSFM has not displaced more traditional imaging methods despite its often-superior performance. One reason for this is that the field has largely conformed to a do-it-yourself ethic, although the challenges of big image data cannot be overstated. With the most powerful implementations of LSFM available to only a few groups worldwide, the scope of this technique is unnecessarily limited...
March 31, 2017: Nature Methods
https://www.readbyqxmd.com/read/28362264/small-magnitude-effect-sizes-in-epigenetic-end-points-are-important-in-children-s-environmental-health-studies-the-children-s-environmental-health-and-disease-prevention-research-center-s-epigenetics-working-group
#14
Carrie V Breton, Carmen J Marsit, Elaine Faustman, Kari Nadeau, Jaclyn M Goodrich, Dana C Dolinoy, Julie Herbstman, Nina Holland, Janine M LaSalle, Rebecca Schmidt, Paul Yousefi, Frederica Perera, Bonnie R Joubert, Joseph Wiemels, Michele Taylor, Ivana V Yang, Rui Chen, Kinjal M Hew, Deborah M Hussey Freeland, Rachel Miller, Susan K Murphy
BACKGROUND: Characterization of the epigenome is a primary interest for children's environmental health researchers studying the environmental influences on human populations, particularly those studying the role of pregnancy and early-life exposures on later-in-life health outcomes. OBJECTIVES: Our objective was to consider the state of the science in environmental epigenetics research and to focus on DNA methylation and the collective observations of many studies being conducted within the Children's Environmental Health and Disease Prevention Research Centers, as they relate to the Developmental Origins of Health and Disease (DOHaD) hypothesis...
April 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28353656/volatiles-emitted-at-different-flowering-stages-of-jasminum-sambac-and-expression-of-genes-related-to-%C3%AE-farnesene-biosynthesis
#15
Ying Yu, Shiheng Lyu, Dan Chen, Yi Lin, Jianjun Chen, Guixin Chen, Naixing Ye
Fresh jasmine flowers have been used to make jasmine teas in China, but there has been no complete information about volatile organic compound emissions in relation to flower developmental stages and no science-based knowledge about which floral stage should be used for the infusion. This study monitored volatile organic compounds emitted from living flowers of Jasminum sambac (L.) Ait. 'Bifoliatum' at five developmental stages and also from excised flowers. Among the compounds identified, α-farnesene, linalool, and benzyl acetate were most abundant...
March 29, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28352244/the-child-attachment-interview-a-narrative-review
#16
REVIEW
Antonella Privizzini
Attachment theory promoted an impressive body of research on the psychic developmental processes, resulting in studies on both typical and atypical development. Much of the diffusion of the attachment theory in the clinical field was related to the design of reliable instruments to evaluate the organization of attachment in infancy as well as in adulthood. Until recently, the lack of a suitable instrument to assess attachment in middle childhood as well as in adolescence hindered the expansion of research in these developmental phases during which the parent-child relationship takes on a different, albeit still crucial, role...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28350985/macrophages-help-cells-connect-to-pattern-zebrafish-stripes
#17
Thomas B Kornberg
Mechanisms that disseminate the proteins that orchestrate organ and tissue development have been a major focus of cell and developmental biology. Reporting in Science, Eom and Parichy (2017) characterize the role that macrophages play in facilitating long-distance signaling between the cells that make stripes in the adult zebrafish.
March 27, 2017: Developmental Cell
https://www.readbyqxmd.com/read/28346755/editorial-child-psychology-and-psychiatry-using-science-to-make-a-difference
#18
EDITORIAL
R M Pasco Fearon
The Journal of Child Psychology and Psychiatry has, I think it is fair to say, a special place in the hearts of scientists and scientist-practitioners working broadly in the field of developmental psychopathology. How would you put into words what it is we all love about the journal? Answers on a postcard please! For me, in addition to the high quality of the science, there is something unique about JCPP's open-minded, eclectic yet rigorous and methodologically pluralistic style that makes it stand out from the rest...
April 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28343098/developmental-validation-of-qiagen-investigator-%C3%A2-24plex-qs-kit-and-investigator-%C3%A2-24plex-go-kit-two-6-dye-multiplex-assays-for-the-extended-codis-core-loci
#19
Melanie Kraemer, Anke Prochnow, Michael Bussmann, Mario Scherer, Ralf Peist, Carolyn Steffen
The original CODIS database based on 13 core STR loci has been overwhelmingly successful for matching suspects with evidence. In order to increase the power of discrimination, reduce the possibility of adventitious matches, and expand global data sharing, the CODIS Core Loci Working Group determined the expansion of the CODIS core loci to 20 STR plus three additional "highly recommended" loci (SE33, DY391, Amelogenin) Hares, 2015, 2012 [1,2]. The QIAGEN Investigator 24plex QS and Investigator 24plex GO! Kits are 6-dye multiplex assays that contain all markers of the expanded 23 CODIS core loci along with a unique internal performance control that is co-amplified with the STR markers...
March 12, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/28335519/translating-developmental-origins-improving-the-health-of-women-and-their-children-using-a-sustainable-approach-to-behaviour-change
#20
Mary Barker, Janis Baird, Tannaze Tinati, Christina Vogel, Sofia Strömmer, Taylor Rose, Rufia Begum, Megan Jarman, Jenny Davies, Sue Thompson, Liz Taylor, Hazel Inskip, Cyrus Cooper, Don Nutbeam, Wendy Lawrence
Theories of the developmental origins of health and disease imply that optimising the growth and development of babies is an essential route to improving the health of populations. A key factor in the growth of babies is the nutritional status of their mothers. Since women from more disadvantaged backgrounds have poorer quality diets and the worst pregnancy outcomes, they need to be a particular focus. The behavioural sciences have made a substantial contribution to the development of interventions to support dietary changes in disadvantaged women...
March 20, 2017: Healthcare (Basel, Switzerland)
keyword
keyword
71202
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"