keyword
https://read.qxmd.com/read/38537084/personal-versus-therapist-perioperative-music-intervention-a-randomized-controlled-trial
#1
JOURNAL ARTICLE
Fan Jiang, Tingting Wang, Liqiong Hu, Shangui Chen, Lijian Chen, Xuesheng Liu, Yao Lu, Erwei Gu, Luis Ulloa
INTRODUCTION: Music interventions can alleviate patient anxiety and improve post-surgical satisfaction. However, it remains uncertain whether music personal preferences affect efficacy. We tested whether personal music intervention with patient-selected songs played ad libitum is more effective than standard therapist-designed treatment with classical music. METHODS: A prospective, parallel-group, single-blinded, randomized controlled trial with 229 participants (aged 18 to 60 y) previously scheduled for elective surgery...
April 3, 2024: International Journal of Surgery
https://read.qxmd.com/read/38535846/plasma-concentrations-of-oral-ondansetron-in-hospitalized-dogs-exhibiting-clinical-signs-of-nausea
#2
JOURNAL ARTICLE
Kristin M Zersen, Angela Molli, Brooke G Weisbeck, Samantha Fedotova, Jessica M Quimby, Daniel L Gustafson, Sarah B Shropshire
The purpose of this study was to evaluate plasma ondansetron (OND) concentrations in a population of dogs with naturally occurring nausea after oral OND administration. Twenty-four dogs were randomly assigned to receive one of the following doses of oral OND: 0.5 mg/kg q8h, 0.5 mg/kg q12h, 1 mg/kg q8h, or 1 mg/kg q12h. Blood samples for plasma OND measurements were collected at baseline and 2, 4, and 8 h after administration of the first dose of OND. OND concentrations averaged over an 8 h time period were not significantly different between dose groups (0...
March 3, 2024: Veterinary Sciences
https://read.qxmd.com/read/38534927/high-symptom-burden-in-patients-receiving-radiotherapy-and-factors-associated-with-being-offered-an-intervention
#3
JOURNAL ARTICLE
Allison Rau, Demetra Yannitsos, Petra Grendarova, Siwei Qi, Linda Watson, Lisa Barbera
Patient report outcomes are commonly collected during oncology visits to elicit symptom burden and guide management. We aimed to determine the frequency of intervention for patients undergoing radiotherapy with high symptom complexity scores and identify which factors are associated with being offered an intervention. A retrospective chart audit was completed of adult patients with cancer who had at least one radiotherapy appointment and were assigned a high symptom complexity. A total of 200 patients were included; 150 (75...
February 27, 2024: Current Oncology
https://read.qxmd.com/read/38533530/are-measures-and-related-symptoms-of-cachexia-recorded-as-outcomes-in-gastrointestinal-cancer-chemotherapy-clinical-trials
#4
JOURNAL ARTICLE
Ross Valaire, Frances Garden, Valentina Razmovski-Naumovski
BACKGROUND: Cachexia is prevalent in gastrointestinal cancers and worsens patient outcomes and chemotherapy compliance. We examined to what extent registered gastrointestinal cancer chemotherapy clinical trials record measures and related symptoms of cachexia as outcomes, and whether these were associated with trial characteristics. METHODS: Four public trial registries (2012-2022) were accessed for Phase II and/or III randomized controlled pancreatic, gastric, and colorectal cancer chemotherapy trial protocols...
March 27, 2024: Journal of Cachexia, Sarcopenia and Muscle
https://read.qxmd.com/read/38532937/the-association-between-intradialytic-symptom-clusters-and-recovery-time-in-patients-undergoing-maintenance-hemodialysis-an-exploratory-analysis
#5
JOURNAL ARTICLE
Arrti A Bhasin, Jennifer M MacRae, Braden Manns, Kelvin C W Leung, Amber O Molnar, Jason W Busse, David Collister, K Scott Brimble, Christian G Rabbat, Jessica Tyrwhitt, Andrea Mazzetti, Michael Walsh
BACKGROUND: Individuals receiving hemodialysis often experience concurrent symptoms during treatment and frequently report feeling unwell after dialysis. The degree to which intradialytic symptoms are related, and which specific symptoms may impair health-related quality of life (HRQoL) is uncertain. OBJECTIVES: To explore intradialytic symptoms clusters, and the relationship between intradialytic symptom clusters with dialysis treatment recovery time and HRQoL...
2024: Canadian Journal of Kidney Health and Disease
https://read.qxmd.com/read/38532868/the-effects-of-drainage-tube-on-pain-and-functional-recovery-after-unicompartmental-knee-arthroplasty
#6
JOURNAL ARTICLE
Ting Fu, Shuzhen Ren, Yu Nie
OBJECTIVE: The objective of this study was to evaluate the impact of drainage tube placement on postoperative pain, recovery, and opioid consumption within a 72-hour period following unicompartmental knee arthroplasty (UKA). METHODS: Patients with medial knee osteoarthritis who underwent UKA from January 2019 to August 2020 were enrolled in the study and divided into two groups based on whether they received a drain postoperatively. RESULTS: The drainage group had significantly lower VAS scores on day 1, day 2, and day 3, in addition to significantly smaller changes in the circumference of the knee joint within 3 days postoperatively (P <0...
2024: Acta Ortopedica Brasileira
https://read.qxmd.com/read/38532799/coexisting-primary-sclerosing-cholangitis-and-autoimmune-hepatitis-overlapping-challenges-in-diagnosis-and-treatment
#7
Hannah W Fiske, Firrah Saeed, Christopher Ward, Boris Sinayuk, Veronica Ulici, Michael Curry, Edward Feller, Samir A Shah
INTRODUCTION: Hepatobiliary overlap syndromes describe the coinciding presentation of more than one immune-mediated biliary and liver disease in a single patient and present complex challenges in diagnosis and treatment. We report a case of ulcerative colitis with primary sclerosing cholangitis and autoimmune hepatitis overlap syndrome responsive to vancomycin. CASE PRESENTATION: The patient is a 30-year-old female with known ulcerative pancolitis and autoimmune hepatitis...
2024: Case Reports in Gastroenterology
https://read.qxmd.com/read/38532541/case-report-of-overlapping-pyloric-obstruction-due-to-dichlorvos-poisoning-and-cholelithiasis-with-choledocholithiasis
#8
JOURNAL ARTICLE
Jie Peng, Yalu Zhang, Qin Ling, Liang Zhu, Hanhui Yao
BACKGROUND Pyloric obstruction after dichlorvos poisoning causes repeated vomiting and inability to eat. Choledocholithiasis and cholelithiasis are the common digestive diseases, with high morbidity and relapse in elderly patients. However, the complex situation of these diseases' coexistence is a clinically intractable problem, and literature on selecting optimal surgical planning is scarce. CASE REPORT A thin 79-year-old woman took dichlorvos due to family conflicts. She improved after being urgently sent to local hospital for gastric lavage and detoxification...
March 27, 2024: American Journal of Case Reports
https://read.qxmd.com/read/38532121/symptom-burden-and-relief-in-palliative-care-units-of-german-comprehensive-cancer-center-and-other-hospitals
#9
JOURNAL ARTICLE
Julia Berendt, Sarah Brunner, Maria Heckel, Mitra Tewes, Christoph Ostgathe, Susanne Gahr
PURPOSE: The National Hospice and Palliative Registry contains patient data from German hospice and palliative care facilities about symptoms. The aim of the study at hand is to differentiate symptom burden of patients in palliative care units between Comprehensive Cancer Center (CCC) and other hospitals regarding symptom burden and relief of patients in palliative care units. METHODS: The registry analysis provided data of patients in palliative care units (2014-2018)...
March 27, 2024: Journal of Cancer Research and Clinical Oncology
https://read.qxmd.com/read/38531572/effects-of-cannabidiol-on-psychosocial-stress-situational-anxiety-and-nausea-in-a-virtual-reality-environment-a-protocol-for-a-single-centre-randomised-clinical-trial
#10
JOURNAL ARTICLE
Zeeta Bawa, Danielle McCartney, Miguel Bedoya-Pérez, Namson S Lau, Richard Fox, Hamish MacDougall, Iain S McGregor
INTRODUCTION: The non-intoxicating plant-derived cannabinoid, cannabidiol (CBD), has demonstrated therapeutic potential in a number of clinical conditions. Most successful clinical trials have used relatively high (≥300 mg) oral doses of CBD. Relatively few studies have investigated the efficacy of lower (<300 mg) oral doses, typical of those available in over-the-counter CBD products. METHODS: We present a protocol for a randomised, double-blind, placebo-controlled, parallel-group clinical trial investigating the effects of a low oral dose (150 mg) of CBD on acute psychosocial stress, situational anxiety, motion sickness and cybersickness in healthy individuals...
March 25, 2024: BMJ Open
https://read.qxmd.com/read/38531283/quadratus-lumborum-block-vs-transversus-abdominis-plane-block-for-postoperative-pain-control-in-patients-with-nephrectomy-a-systematic-review-and-network-meta-analysis
#11
REVIEW
Tianyu Gao, Yigang Wang, Yuxin Zheng, Yonghao Yu, Qing Li, Linlin Zhang
STUDY OBJECTIVE: This systematic review and network meta-analysis aimed to compare the analgesic efficacy of transversus abdominis plane block (TAPB) and quadratus lumborum block (QLB) on nephrectomy. DESIGN: Systematic review and network meta-analysis. PATIENTS: Patients undergoing nephrectomy. INTERVENTIONS: TAPB and QLB for postoperative analgesia. MEASUREMENTS: The primary outcome was 24 h morphine-equivalent consumptions after surgery...
March 25, 2024: Journal of Clinical Anesthesia
https://read.qxmd.com/read/38531179/perioperative-intravenous-infusion-of-dexmedetomidine-for-alleviating-postpartum-depression-after-cesarean-section-a-meta-analysis-and-systematic-review
#12
REVIEW
Shouyu Xu, Yingyong Zhou, Saiying Wang, Qiuwen Li, Yunfei Feng, Liang Chen, Kaiming Duan
The efficacy of perioperative dexmedetomidine (DEX) infusion as a precaution against postpartum depression (PPD) in women undergoing cesarean section has not been substantiated systematically. A literature search for RCTs on DEX against PPD was retrieved in the following databases from inception to January 3, 2024: PubMed, Embase, Web of Science, the Cochrane Library, CNKI, Wanfang, CBM, VIP, etc. A total of 13 RCTs with 1711 participants were included. Meta-analysis was performed by RevMan5.3 and Stata16 using a random-effects model...
March 21, 2024: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/38531058/the-effects-of-emotional-freedom-techniques-implemented-during-early-pregnancy-on-nausea-vomiting-severity-and-anxiety-a-randomized-controlled-trial
#13
JOURNAL ARTICLE
Sinem Güven Santur, Zeliha Özşahin
Objective: This randomized controlled trial investigated the effect of emotional freedom techniques (EFT) on the severity of nausea-vomiting and anxiety in early pregnancy. Design: The sample consisted of 131 pregnant women in the experimental and control groups between 6 and 16 weeks of pregnancy attending an antenatal clinic. Participants were randomly assigned to receive training on EFT or a control group. Data were collected using a personal information form, subjective experiences, the Pregnancy-Related Anxiety Questionnaire, and the Pregnancy-Unique Quantification of Emesis...
March 27, 2024: J Integr Complement Med
https://read.qxmd.com/read/38530162/the-effect-of-nurse-led-remote-telephone-triage-on-symptom-management-of-patients-with-cancer-a-systematic-review-and-meta-analysis
#14
REVIEW
Merve Gozde Sezgin, Hicran Bektas
BACKGROUND: Cancer patients experience many symptoms. Nurse-led remote telephone triage can improve their quality of life by contributing to the management of these symptoms. AIMS: This study aimed to investigate the effects of nurse-led remote telephone triage on symptom management of patients with cancer. METHODS: The searches were conducted in 10 databases and gray literature from May 2023 to July 2023 without any year limitations. A fixed-effects model was used in the meta-analysis...
March 26, 2024: Worldviews on Evidence-based Nursing
https://read.qxmd.com/read/38530160/a-phase-0-1-pharmacokinetic-and-pharmacodynamics-and-safety-and-tolerability-study-of-letrozole-in-combination-with-standard-therapy-in-recurrent-high-grade-gliomas
#15
JOURNAL ARTICLE
Pankaj B Desai, Aniruddha Karve, Misam Zawit, Priyanka Arora, Nimita Dave, Joy Awosika, Ningjing Li, Bethany Fuhrman, Mario Medvedovic, Larry Sallans, Ady Kendler, Biplab DasGupta, David Plas, Richard Curry, Mario Zuccarello, Rekha Chaudhary, Soma Sengupta, Trisha M Wise-Draper
PURPOSE: High grade gliomas (HGGs) carry a poor prognosis, with glioblastoma accounting for almost 50% of primary brain malignancies in the elderly. Unfortunately, despite the use of multiple treatment modalities, the prognosis remains poor in this population. Our pre-clinical studies suggest that the presence of aromatase expression, encoded by CYP19A1, is significantly upregulated in HGGs. Remarkably, we find that letrozole (LTZ), an FDA approved aromatase inhibitor, has marked activity against HGGs...
March 26, 2024: Clinical Cancer Research
https://read.qxmd.com/read/38529438/unveiling-the-enigma-of-a-colonic-neuroendocrine-tumor-causing-ileocolic-intussusception-a-case-report
#16
Natalie Mesa, Lizis O Rodriguez, Mitchel Lacey, Rupa Seetharamaiah
Intussusception in adults is rare and is often associated with a pathologic lead point. While colonic adenocarcinoma is a common cause, well-differentiated colonic neuroendocrine tumors are exceedingly rare. We present a unique case of an ileocolic intussusception due to a distal ascending colonic neuroendocrine tumor, emphasizing the diagnostic challenges and importance of prompt intervention. A 60-year-old male with a previous screening colonoscopy in June of 2022 presented to the Emergency Department with two days of cramping, right upper abdominal pain with associated nausea and two episodes of emesis...
February 2024: Curēus
https://read.qxmd.com/read/38529378/management-of-trastuzumab-deruxtecan-related-nausea-and-vomiting-in-real-world-practice
#17
JOURNAL ARTICLE
Giulia Notini, Matteo Maria Naldini, Lorenzo Sica, Giulia Viale, Alessia Rognone, Stefania Zambelli, Patrizia Zucchinelli, Marta Piras, Carlo Bosi, Marco Mariani, Daniela Aldrighetti, Giampaolo Bianchini, Luca Licata
BACKGROUND: Nausea and vomiting are common side effects of Trastuzumab Deruxtecan (T-DXd), but guidelines for optimal management were not initially available. This retrospective single-center study aimed at evaluating the efficacy of two antiemetic regimens in patients receiving T-DXd. METHODS: Data from metastatic breast cancer patients receiving T-DXd were collected. Two groups were defined: patients treated with 5-HT3 receptor antagonists (RA) ± dexamethasone (5-HT3-group) and patients treated with a fixed oral combination of netupitant (NK1RA) and palonosetron ± dexamethasone (NK1 group)...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38529122/the-perilous-consequences-of-bowel-preparation-a-case-study-with-literature-review-of-boerhaave-syndrome
#18
Ruo-Yu Gao, Xiao-Lan Wei, Jin-Feng Wu, Zhi-Wei Zhou, Xi-Qiu Yu
Colonoscopy is widely acknowledged as a prevalent and efficacious approach for the diagnosis and treatment of gastrointestinal disorders. In order to guarantee an effective colonoscopy, it is imperative for patients to undergo an optimal bowel preparation regimen. This entails the consumption of a substantial volume of a non-absorbable solution to comprehensively purge the colon of any fecal residue. Nevertheless, it is noteworthy to acknowledge that the bowel preparation procedure may occasionally elicit adverse symptoms such as nausea and vomiting...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38528196/nonocclusive-mesenteric-ischemia-nomi-on-roux-limb-after-biliary-reconstruction-successfully-treated-by-interventional-radiology-ivr
#19
JOURNAL ARTICLE
Makoto Kawamoto, Yoshihiro Miyasaka, Nobuhiko Koreeda, Yousuke Hirano, Ryotaro Yamamoto, Masato Watanabe
Nonocclusive mesenteric ischemia (NOMI) is a life-threatening disorder. Early diagnosis is challenging because NOMI lacks specific symptoms. A 52-year-old man who received extended cholecystectomy with Roux-en-Y hepaticojejunostomy for gallbladder cancer (GBC) presented to our hospital with nausea and vomiting. Neither tender nor peritoneal irritation sign was present on abdominal examination. Blood test exhibited marked leukocytosis (WBC:19,800/mm3). A contrast-enhanced abdominal computed tomography (CT) scan revealed remarkable wall thickening and lower contrast enhancement effect localized to Roux limb...
March 25, 2024: Clinical Journal of Gastroenterology
https://read.qxmd.com/read/38527735/use-of-thiamine-supplementation-in-pregnant-women-diagnosed-with-hyperemesis-gravidarum-and-wernicke-encephalopathy
#20
JOURNAL ARTICLE
Angela Feagan Clark
Hyperemesis gravidarum is the most common condition requiring hospital care for women during the first 20 weeks of pregnancy and may lead to malnutrition, dehydration, and vitamin deficiencies. Depletion of vitamins such as thiamine may result in the development of Wernicke encephalopathy, a severe neurological disorder that can increase the risk for mortality and morbidity for the mother and fetus. A lack of awareness regarding the relationship of hyperemesis gravidarum and Wernicke encephalopathy may result in delayed treatment and disease management...
March 22, 2024: Nursing for Women's Health
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