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Daniel S Churgin, Kimberly D Tran, Ninel Z Gregori, Ryan C Young, Chrisfouad Alabiad, Harry W Flynn
Purpose: To describe a case of Multi-drug resistant Mycobacterium chelonae scleral buckle infection. Observations: A 56 year-old male with history of retinal detachment repair with scleral buckle 20 years prior presented with 8 months of intermittent pain and redness in the left eye. The patient was diagnosed with scleral buckle infection, the buckle was removed, and cultures revealed multi-drug resistant Mycobacterium chelonae. The postoperative course included orbital cellulitis treated with systemic linezolid, clarithromycin, and imipenem...
June 2018: American Journal of Ophthalmology Case Reports
Arezu Haghighi, Jiun Do, Hossein Ameri
Purpose: To describe the clinical course of a patient with persistent subretinal fluid (SRF) after primary scleral buckle surgery for a rhegmatogenous retinal detachment (RRD) repair who was subsequently treated with oral eplerenone for resolution of SRF. Observations: A 34 year-old-male presented with a large bullous macula-involving RRD of unknown duration and underwent primary scleral buckle and retinotomy for drainage of subretinal fluid (SRF). His post-operative course was characterized by persistent macular SRF for 1...
June 2018: American Journal of Ophthalmology Case Reports
Nathan L Scott, Jayanth Sridhar, Harry W Flynn
Purpose: To describe the management of a giant retinal tear with retinal detachment in a patient with active toxoplasmosis retinochoroiditis. Results: While receiving systemic medications for toxoplasmosis, the patient underwent scleral buckling, pars plana vitrectomy, and C3F8 gas tamponade without removal of the lens. At last follow-up, best corrected visual acuity was 20/20 with an attached retina and the toxoplasmosis lesion was inactive. Conclusions: and Importance: Using modern surgical techniques, anatomic and clinical success is possible during active retinochoroiditis...
June 2018: American Journal of Ophthalmology Case Reports
David G Kidd, Jeremiah Singer, Richard Huey, Laura Kerfoot
INTRODUCTION: Seat belts reduce the risk of fatal injury in a crash, yet in 2015, nearly 10,000 people killed in passenger vehicles were unrestrained. Enhanced seat belt reminders increase belt use, but a gearshift interlock that prevents the vehicle from being placed into gear unless the seat belt is used may prove more effective. METHOD: Thirty-two people with a recent seat belt citation and who admitted to not always using a seat belt as a driver were recruited as part-time belt users and asked to evaluate two new vehicles...
June 2018: Journal of Safety Research
Hanqing Nan, Long Liang, Guo Chen, Liyu Liu, Ruchuan Liu, Yang Jiao
Three-dimensional (3D) collective cell migration in a collagen-based extracellular matrix (ECM) is among one of the most significant topics in developmental biology, cancer progression, tissue regeneration, and immune response. Recent studies have suggested that collagen-fiber mediated force transmission in cellularized ECM plays an important role in stress homeostasis and regulation of collective cellular behaviors. Motivated by the recent in vitro observation that oriented collagen can significantly enhance the penetration of migrating breast cancer cells into dense Matrigel which mimics the intravasation process in vivo [Han et al...
March 2018: Physical Review. E
Xu Zhang, Xiaoyu Du, Dejian Li, Rongguang Ao, Bin Yu, Baoqing Yu
Pearl has great potential as a natural biomaterial for bone tissue engineering, but it suffers from low porosity, difficulty in molding, and poor anti-buckling property. In this study, we used the 3-D printing technique to fabricate original pearl powder and PCL composite scaffolds with different concentrations of pearl powder. The four groups of scaffolds were termed PCL, 30% Pearl/PCL, 50% Pearl/PCL and 80% Pearl/PCL scaffolds according to the proportion of pearl powder. The samples were systematically investigated by scanning electron microscopy (SEM), wide-angle XRD, liquid substitution, Zwick static materials testing, and energy dispersive X-ray analysis...
May 16, 2018: Journal of Biomaterials Science. Polymer Edition
J M Kim, S Choi, S W Lee, K Park
Branching morphogenesis is a crucial part of early developmental processes in diverse organs, but the detailed mechanism of this morphogenic event remains to be elucidated. Here we introduce an unknown mechanism leading to branching morphogenesis using mouse embryonic organotypic cultures with time-lapse live imaging. We found spatially expressed L-type voltage-dependent Ca2+ channels (VDCCs) in the peripheral layers of developing epithelial buds and identified the VDCCs as a core signaling mediator for patterning branching architecture...
May 15, 2018: Scientific Reports
Caner Öztürk, Almila Sarıgül Sezenöz, Gürsel Yılmaz, İmren Akkoyun
Here we present the long-term anatomical and visual outcomes of bilateral asymmetric rhegmatogenous retinal detachment repair in a patient with Stickler syndrome. A 17-year-old girl presented with decreased visual acuity in both eyes for more than one year. Her best-corrected visual acuity (BCVA) was 0.1 in the right eye and 0.05 in the left eye. Slit-lamp anterior segment examination revealed subcapsular cataract in both eyes. Fundus examination showed bilateral rhegmatogenous retinal detachment, chronic retinal detachment accompanied by multiple retinal holes, tears and membranous fibrillary vitreous in the peripheral retina...
April 2018: Turkish Journal of Ophthalmology
Jacob A Klapper
No abstract text is available yet for this article.
April 14, 2018: Journal of Thoracic and Cardiovascular Surgery
Sen Zhang, Xiaoyu Luo, Zongxi Cai
We study the collapsible behaviour of a vessel conveying viscous flows subject to external pressure, a scenario that could occur in many physiological applications. The vessel is modelled as a three-dimensional cylindrical tube of nonlinear hyperelastic material. To solve the fully coupled fluid-structure interaction, we have developed a novel approach based on the Arbitrary Lagrangian-Eulerian (ALE) method and the frontal solver. The method of rotating spines is used to enable an automatic mesh adaptation...
May 9, 2018: Biomechanics and Modeling in Mechanobiology
Seonjoo Lee, Molly E Zimmerman, Atul Narkhede, Sara E Nasrabady, Giuseppe Tosto, Irene B Meier, Tammie L S Benzinger, Daniel S Marcus, Anne M Fagan, Nick C Fox, Nigel J Cairns, David M Holtzman, Virginia Buckles, Bernardino Ghetti, Eric McDade, Ralph N Martins, Andrew J Saykin, Colin L Masters, John M Ringman, Stefan Fӧrster, Peter R Schofield, Reisa A Sperling, Keith A Johnson, Jasmeer P Chhatwal, Stephen Salloway, Stephen Correia, Clifford R Jack, Michael Weiner, Randall J Bateman, John C Morris, Richard Mayeux, Adam M Brickman
INTRODUCTION: White matter hyperintensity (WMH) volume on MRI is increased among presymptomatic individuals with autosomal dominant mutations for Alzheimer's disease (AD). One potential explanation is that WMH, conventionally considered a marker of cerebrovascular disease, are a reflection of cerebral amyloid angiopathy (CAA) and that increased WMH in this population is a manifestation of this vascular form of primary AD pathology. We examined whether the presence of cerebral microbleeds, a marker of CAA, mediates the relationship between WMH and estimated symptom onset in individuals with and without autosomal dominant mutations for AD...
2018: PloS One
Amit Agarwal, Miriam S Vitiello, Leonardo Viti, Anna Cupolillo, Antonio Politano
Herein, we explore the main features and the prospect of plasmonics with two-dimensional semiconductors. Plasmonic modes in each class of van der Waals semiconductors have their own peculiarities, along with potential technological capabilities. Plasmons of transition-metal dichalcogenides share features typical of graphene, due to their honeycomb structure, but with damping processes dominated by intraband rather than interband transitions, unlike graphene. Spin-orbit coupling strongly affects the plasmonic spectrum of buckled honeycomb lattices (silicene and germanene), while the anisotropic lattice of phosphorene determines different propagation of plasmons along the armchair and zigzag directions...
May 9, 2018: Nanoscale
Toyo Kazu Yamada, Hidetp Fukuda, Taizo Fujiwara, Polin Liu, Kohji Nakamura, Seiya Kasai, Amadeo Lopez Vazquez de Parga, Hirofumi Tanaka
Band gap opening of a single-layer graphene nanoribbon (sGNR) sitting on another sGNR, fabricated by drop casting GNR solution on Au(111) substrate in air, was studied by means of scanning tunneling microscopy (STM) and spectroscopy (STS) in ultra-high vacuum (UHV) at 78 K and 300 K. GNRs with a width of ~45 nm were prepared by unzipping double-walled carbon nanotubes (diameter ~15 nm) with ultrasonic method. In contrast to atomically-flat GNRs fabricated via the bottom-up process, the drop cast sGNRs were buckled on Au(111), i...
May 9, 2018: Nanotechnology
Taisiya Sigaeva, Robert Mangan, Luigi Vergori, Michel Destrade, Les Sudak
We study what is clearly one of the most common modes of deformation found in nature, science and engineering, namely the large elastic bending of curved structures, as well as its inverse, unbending, which can be brought beyond complete straightening to turn into eversion. We find that the suggested mathematical solution to these problems always exists and is unique when the solid is modelled as a homogeneous, isotropic, incompressible hyperelastic material with a strain-energy satisfying the strong ellipticity condition...
April 2018: Proceedings. Mathematical, Physical, and Engineering Sciences
B Szafran, D Żebrowski, Alina Mreńca-Kolasińska
We study electrostatic quantum dot confinement for charge carriers in silicene. The confinement is formed by vertical electric field surrounding the quantum dot area. The resulting energy gap in the outside of the quantum dot traps the carriers within, and the difference of electrostatic potentials on the buckled silicene sublattices produces nonzero carrier masses outside the quantum dot. We study the electrostatic confinement defined inside a silicene flake with both the atomistic tight-binding approach as well as with the continuum approximation for a circularly symmetric electrostatic potential...
May 8, 2018: Scientific Reports
Zhi Jiang, Kenjiro Fukuda, Xiaomin Xu, Sungjun Park, Daishi Inoue, Hanbit Jin, Masahiko Saito, Itaru Osaka, Kazuo Takimiya, Takao Someya
Mechanically durable transparent electrodes are needed in flexible optoelectronic devices to realize their long-term stable functioning, for applications in various fields such as energy, healthcare, and soft robotics. Several promising transparent electrodes based on nanomaterials have been previously reported to replace the conventional and fragile indium-tin oxide (ITO); however, obtaining feasible printed transparent electrodes for ultraflexible devices with a multistack structure is still a great challenge...
May 7, 2018: Advanced Materials
Jingjing Liu, Yang Yang, Pengbo Lyu, Petr Nachtigall, Yuxi Xu
Silicene, a 2D silicon allotrope with unique low-buckled structure, has attracted increasing attention in recent years due to its many superior properties. So far, epitaxial growth is one of the very limited ways to obtain high-quality silicene, which severely impedes the research and application of silicene. Therefore, large-scale synthesis of silicene is a great challenge, yet urgently desired. Herein, the first scalable preparation of free-standing high-quality silicene nanosheets via liquid oxidation and exfoliation of CaSi2 is reported...
May 7, 2018: Advanced Materials
James Fodor, Blake T Riley, Natalie A Borg, Ashley M Buckle
A structural characterization of the interaction between αβ TCRs and cognate peptide-MHC (pMHC) is central to understanding adaptive T cell-mediated immunity. X-ray crystallography, although the source of much structural data, traditionally provides only a static snapshot of the protein. Given the emerging evidence for the important role of conformational dynamics in protein function, we interrogated 309 crystallographic structures of pMHC complexes using ensemble refinement, a technique that can extract dynamic information from the x-ray data...
May 4, 2018: Journal of Immunology: Official Journal of the American Association of Immunologists
Mukesh Tripathi, Alexander V Markevich, Roman Boettger, Stefan Facsko, Elena Besley, Jani Kotakoski, Toma Susi
Incorporating heteroatoms into the graphene lattice may be used to tailor its electronic, mechanical and chemical properties, although directly observed substitutions have thus far been limited to incidental Si impurities and P, N and B dopants introduced using low-energy ion implantation. We present here the heaviest impurity to date, namely $^{74}$Ge$^+$ ions implanted into monolayer graphene. Although sample contamination remains an issue, atomic resolution scanning transmission electron microscopy imaging and quantitative image simulations show that Ge can either directly substitute single atoms, bonding to three carbon neighbors in a buckled out-of-plane configuration, or occupy an in-plane position in a divacancy...
May 4, 2018: ACS Nano
Olga Yakubovich, Galina Kiriukhina, Larisa Shvanskaya, Olga Maximova, Anatoliy Volkov, Olga Dimitrova, Evgeniy Ovchenkov, Oleg Yumashev, Asif Iqbal, Badiur Rahaman, Tanusri Saha-Dasgupta, Alexander Vasiliev
Rubidium tetramanganese tris(phosphate), RbMn4 (PO4 )3 , has been synthesized as single crystals under hydrothermal conditions. The crystal structure was refined in the space group Pnnm (D2h 12 ). It is argued that the size factor RM /RA , i.e. the ratio of the A+ ionic radius to the M2+ ionic radius, within the morphotropic series AM4 (TO4 )3 corresponds to a specific type of crystal structure. At low temperatures, the antiferromagnet superimposed on a buckled kagomé network in RbMn4 (PO4 )3 experiences a transition into a long-range ordered state with finite spontaneous magnetization...
May 1, 2018: Acta Crystallographica. Section C, Structural Chemistry
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