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Captopril renography

Ping-Ju Hsieh, Yen-Shu Kuo, Meng-Lin Chen, Ching-Ling Lin, Hung-Yi Su
A positive captopril renography indicates that patient's hypertension is renin dependent, most commonly caused by renal artery stenosis. The authors reported a case of positive captopril renography; however, CT demonstrated that renal arteries were intact, but there was a huge chromophobe renal cell carcinoma. Renin-dependent hypertension was relieved soon after nephrectomy. It is an uncommon cause of positive captopril renography.
September 11, 2017: Clinical Nuclear Medicine
Malin Andersson, Karl Jägervall, Per Eriksson, Anders Persson, Göran Granerus, Chunliang Wang, Örjan Smedby
BACKGROUND: Although it is well known that renal artery stenosis may cause renovascular hypertension, it is unclear how the degree of stenosis should best be measured in morphological images. The aim of this study was to determine which morphological measures from Computed Tomography Angiography (CTA) and Magnetic Resonance Angiography (MRA) are best in predicting whether a renal artery stenosis is hemodynamically significant or not. METHODS: Forty-seven patients with hypertension and a clinical suspicion of renovascular hypertension were examined with CTA, MRA, captopril-enhanced renography (CER) and captopril test (Ctest)...
2015: BMC Medical Imaging
Ali F AbuRahma, Michael Yacoub
Renal artery stenosis (RAS) is one of the most common causes of severe hypertension (approximately 1-5% of all patients with hypertension). Presently, there is no universally accepted screening test for RAS. However, most clinicians use renal duplex ultrasound (RDU) imaging; while others use magnetic resonance angiography (MRA) or contrast computed tomography angiography in selected patients. This review will highlight various imaging modalities and discuss the pros and cons of each.
December 2013: Seminars in Vascular Surgery
T Suzuki, M Nangaku, S Oku, H Takemura, Y Yokoyama, Y Takahashi, T Fujita
We describe a 19-year-old man who developed muscle weakness due to hypokalemia. His blood pressure on admission was considered to be relatively high, and we performed captopril renography. His baseline renogram was normal, while the results of captopril renography showed delayed patterns similar to those of renovascular hypertension. However, his blood pressure level decreased and returned to the normal range without medication 2 weeks after admission. Our final diagnosis in this patient was Barter's syndrome...
September 2002: Clinical and Experimental Nephrology
A Granata, F Fiorini, S Andrulli, F Logias, M Gallieni, G Romano, E Sicurezza, C E Fiore
Renovascular disease is a complex disorder, most commonly caused by fibromuscular dysplasia and atherosclerotic diseases. It can be found in one of three forms: asymptomatic renal artery stenosis (RAS), renovascular hypertension, and ischemic nephropathy. Particularly, the atherosclerotic form is a progressive disease that may lead to gradual and silent loss of renal function. Thus, early diagnosis of RAS is an important clinical objective since interventional therapy may improve or cure hypertension and preserve renal function...
December 2009: Journal of Ultrasound
Gerson Alves Pereira Júnior, Valdair Francisco Muglia, Antônio Carlos Dos Santos, Cecilia Hissae Miyake, Fernando Nobre, Mery Kato, Marcus Vinicius Simões, José Ivan de Andrade
OBJECTIVE: To evaluate the anatomical and functional renal alterations and the association with post-traumatic arterial hypertension. METHODS: The studied population included patients who sustained high grades renal injury (grades III to V) successfully non-operative management after staging by computed tomography over a 16-year period. Beyond the review of medical records, these patients were invited to the following protocol: clinical and laboratory evaluation, abdominal computed tomography, magnetic resonance angiography, DMSA renal scintigraphy, and ambulatory blood pressure monitoring...
2012: World Journal of Emergency Surgery: WJES
Chia-Ter Chao
A 22-year-old healthy woman visited our clinic for seizure and consciousness loss. A thorough history taking and physical examination was negative except for persistent high blood pressure. Serial workup for suspicious secondary hypertension revealed secondary hyperaldosteronism. Further image study showed diminished unilateral kidney size, but the computed tomographic angiogram was unremarkable. Radionuclide renography disclosed a specific pattern of compromised unilateral renal function after captopril challenge, suggesting a high probability of renal artery stenosis...
2011: Internal Medicine
Manolis S Kallistratos, Andreas Giannakopoulos, Vasilios German, Athanasios J Manolis
No abstract text is available yet for this article.
November 2010: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
Per Eriksson, Ahmed Abdulilah Mohammed, Jakob De Geer, Johan Kihlberg, Anders Persson, Göran Granerus, Fredrik Nyström, Örjan Smedby
BACKGROUND: The diagnostic value of non-invasive methods for diagnosing renal artery stenosis in patients with renal insufficiency is incompletely known. METHODS: Forty-seven consecutive patients with moderately impaired renal function and a clinical suspicion of renal artery stenosis were investigated with computed tomography angiography (CTA), gadolinium-enhanced magnetic resonance angiography (MRA), contrast-enhanced Doppler ultrasound and captopril renography...
November 2010: Nephrology, Dialysis, Transplantation
S Ajmi, K Ben Ali, M Guezguez, R Sfar, M Nouira
Hydronephrotic kidney with a differential renal function greater than 55% is defined as supranormal. The signification of this finding remains controversial. In this article, the authors reported a case of supranormal function in obstructive hydronephrosis. Differential renal functions were evaluated after administration of captopril and after pyeloplasty. The role of captopril renography as a prognostic factor for surgery is discussed.
January 2010: Revista Española de Medicina Nuclear
György Sandor Reusz, Eva Kis, Orsolya Cseprekál, Attila Jozsef Szabó, Eva Kis
Hypertension in childhood is no longer a rare condition mainly secondary to renal, or renovascular diseases, as a growing proportion of children are obese and hypertensive, with the phenotype of metabolic syndrome. Thus, we need to reconsider our practice in the examination of the hypertensive child and redefine the place of non-invasive methods for screening of renovascular hypertension, and specifically, to evaluate the value of captopril-enhanced renal scintigraphy at the two ends of the palette: the obese child with hypertension and the severely hypertensive prepubertal child...
February 2010: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
Erling Bjerregaard Pedersen, Ulrik Bjørn Andersen
Screening for renal artery stenosis (RAS) should be restricted to patients with a high RAS risk. Captopril renography, computed tomography (CT)-angiography, magnetic resonance (MR)-angiography and ultrasound (US) Doppler can be used. Most patients should receive medical treatment. If predictive tests suggest a good outcome, revascularisation with percutaneous transluminal renal angioplasty (PTRA) should be considered in patients with refractory hypertension, fibromuscular dysplasia, recurrent pulmonary oedema, bilateral renal artery stenosis or progressive azotaemia, and in patients with a narrow stenosis to a single kidney...
June 15, 2009: Ugeskrift for Laeger
Ola Thorsson, Agneta Bjuväng, Göran Granerus
BACKGROUND: The aim of this study was to evaluate the efficiency of captopril renography to detect renovascular hypertension (RVH) using the standardized test criteria established at the consensus conference in Santa Fe 1995. The evaluation was made prospectively and in a clinical situation. METHODS: Renal scintigraphy was performed with Tc-MAG3 according to a 2-day protocol in patients receiving 25 mg captopril 1 h before the test. A baseline study was added only in patients showing abnormal findings in the captopril-stimulated study...
June 2009: Nuclear Medicine Communications
Bilge Volkan-Salanci, Selcuk Dagdelen, Mehmet Alikasifoglu, Tomris Erbas, Mutlu Hayran, Belkis Erbas
INTRODUCTION: The aim of this study was to document the impact of renin-angiotensin system (RAS) polymorphisms on renal haemodynamics and renal hormones in type 2 diabetes mellitus. MATERIALS AND METHODS: Fifty-nine adult patients were studied. Renal haemodynamics were evaluated using 99mTc-MAG3 clearance (MAG3( Cle)) using Bubeck's method and captopril renogram. RAS hormones and angiotensin-converting enzyme (ACE) levels were measured before and after captopril...
March 2009: Journal of the Renin-angiotensin-aldosterone System: JRAAS
M E Schachter, N Zalunardo, C Rose, P Taylor, C Buller, M Kiaii, J Duncan, A Levin
BACKGROUND: Cardiologists often identify atherosclerotic renal artery stenosis (ARAS) during cardiac angiography. The importance of such 'incidental' ARAS (iARAS) is not known. The present study sought to describe renal perfusion using non-captopril (baseline) nuclear renograms in patients with iARAS, and to determine characteristics associated with a positive captopril renogram. METHODS: Patients presenting for non-emergent coronary angiography between June 2001 and February 2006 were angiographically screened for iARAS...
2009: American Journal of Nephrology
William J Elliott
Renovascular hypertension, the most common remediable cause of elevated blood pressure, is a controversial topic, but most authorities agree on several principles. The absolute risk of renovascular hypertension for a specific patient can be estimated using only clinical information, thereby sparing many patients further expensive and potentially dangerous evaluations. Patients with a high absolute risk of renovascular hypertension should have angiography only if they are willing to undergo revascularization if warranted...
July 2008: Journal of Clinical Hypertension
Lars Burchardt, Jan Abrahamsen
A patient story regarding a young man with hypertension and bilateral renal artery stenosis is presented. The value of renography/captopril renography in connection with selective renal vein renin sampling is discussed.
June 2, 2008: Ugeskrift for Laeger
Takafumi Okura, Jun Irita, Daijiro Enomoto, Seiko Manabe, Mie Kurata, Ken-Ichi Miyoshi, Tomikazu Fukuoka, Jitsuo Higaki
A 34-year-old woman was admitted to our hospital because of hypertension with hypokalemia. Her past medical history revealed that at age 24 she had been diagnosed with left renal lithiasis and had undergone extracorporeal shock-wave lithotripsy (ESWL). Physical examination showed that her peripheral pulses were intact and no peripheral edema or audible bruits were detected. Her serum potassium concentration was 2.7 mEq/mL, her plasma aldosterone concentration (PAC) was 96.7 ng/dL, and her plasma renin activity (PRA) was 28...
February 2008: Hypertension Research: Official Journal of the Japanese Society of Hypertension
V Kempi
AIM: Multivariate statistical methods can be used for objective analysis. The emphasis is on analysing renal function parameters together, not one at a time. The aim is to identify curve parameters useful in making predictions in kidneys with and without renal artery stenosis (RAS). PATIENTS, METHODS: 68 patients with resistant hypertension were subjected to captopril renography with (99m)Tc-DTPA. Variants of background areas and background subtraction methods were employed...
2007: Nuklearmedizin. Nuclear Medicine
H Eklöf, H Ahlström, A Magnusson, L-G Andersson, B Andrén, A Hägg, D Bergqvist, R Nyman
PURPOSE: To prospectively compare the diagnostic accuracy of duplex ultrasonography, captopril renography, computed tomography angiography (CTA), and 3D Gd magnetic resonance angiography (MRA) in diagnosing hemodynamically significant renal artery stenosis (RAS). MATERIAL AND METHODS: The standard of reference was measurement of transstenotic pressure gradient. Fifty-eight hypertensive patients with suspicion of RAS were evaluated, when possible, by all five techniques...
October 2006: Acta Radiologica
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